Oncogenesis

Mitotic MTH1 inhibitor TH1579 induces PD-L1 expression and inflammatory response through the cGAS-STING pathway.

Shen J, Guillén Mancina E, Chen S, ..., Sanjiv K, Helleday T

Oncogenesis 13 (1) 17 [2024-05-25; online 2024-05-25]

MYCN induces cell-specific tumorigenic growth in RB1-proficient human retinal organoid and chicken retina models of retinoblastoma.

Blixt MKE, Hellsand M, Konjusha D, ..., Ring H, Hallböök F

Oncogenesis 11 (1) 34 [2022-06-21; online 2022-06-21]

LXRα limits TGFβ-dependent hepatocellular carcinoma associated fibroblast differentiation.

Morén A, Bellomo C, Tsubakihara Y, ..., Heldin CH, Moustakas A

Oncogenesis 8 (6) 36 [2019-05-16; online 2019-05-16]

The deubiquitinating enzymes USP4 and USP17 target hyaluronan synthase 2 and differentially affect its function.

Mehić M, de Sa VK, Hebestreit S, Heldin CH, Heldin P

Oncogenesis 6 (6) e348 [2017-06-12; online 2017-06-12]

The spliceosome U2 snRNP factors promote genome stability through distinct mechanisms; transcription of repair factors and R-loop processing.

Tanikawa M, Sanjiv K, Helleday T, Herr P, Mortusewicz O

Oncogenesis 5 (12) e280 [2016-12-19; online 2016-12-19]

hMYH and hMTH1 cooperate for survival in mismatch repair defective T-cell acute lymphoblastic leukemia.

Eshtad S, Mavajian Z, Rudd SG, ..., Altun M, Helleday T

Oncogenesis 5 (12) e275 [2016-12-05; online 2016-12-05]