Plasma Mannose Levels Are Associated with Incident Type 2 Diabetes and Cardiovascular Disease.

Mardinoglu A, Stančáková A, Lotta LA, Kuusisto J, Boren J, Blüher M, Wareham NJ, Ferrannini E, Groop PH, Laakso M, Langenberg C, Smith U

Cell Metab. 26 (2) 281-283 [2017-08-01; online 2017-08-03]

Plasma mannose levels are elevated in subjects with insulin resistance independently of obesity. Here, we found that elevated plasma mannose levels are strong markers of future risk of several chronic diseases including T2D, CVD, and albuminuria, and that it may contribute to their development rather than just being a novel biomarker.

Adil Mardinoglu

Fellows programme

PubMed 28768165

DOI 10.1016/j.cmet.2017.07.006

Crossref 10.1016/j.cmet.2017.07.006

pii: S1550-4131(17)30427-8