Xenobiotica

In silico predictions of the human pharmacokinetics/toxicokinetics of 65 chemicals from various classes using conformal prediction methodology.

Fagerholm U, Hellberg S, Alvarsson J, Spjuth O

Xenobiotica 52 (2) 113-118 [2022-02-00; online 2022-03-16]

In silico prediction of volume of distribution of drugs in man using conformal prediction performs on par with animal data-based models.

Fagerholm U, Hellberg S, Alvarsson J, Arvidsson McShane S, Spjuth O

Xenobiotica 51 (12) 1366-1371 [2021-12-00; online 2021-12-08]

Comparison between lab variability and in silico prediction errors for the unbound fraction of drugs in human plasma.

Fagerholm U, Spjuth O, Hellberg S

Xenobiotica 51 (10) 1095-1100 [2021-10-00; online 2021-08-13]

The downfall of TBA-354 - a possible explanation for its neurotoxicity via mass spectrometric imaging.

Ntshangase S, Shobo A, Kruger HG, ..., Govender T, Baijnath S

Xenobiotica 48 (9) 938-944 [2018-09-00; online 2017-10-13]

Affiliated researcher

Regulation of cerebral CYP2D alters tramadol metabolism in the brain: interactions of tramadol with propranolol and nicotine.

Wang Q, Han X, Li J, ..., Dong G, Yue J

Xenobiotica 45 (4) 335-344 [2015-04-00; online 2014-11-12]

DDLS Fellow Qiaoli Wang