iScience

Inference of drug off-target effects on cellular signaling using interactome-based deep learning.

Meimetis N, Lauffenburger DA, Nilsson A

iScience 27 (4) 109509 [2024-04-19; online 2024-03-14]

Avlant Nilsson DDLS Fellow

Characterization of an in vitro steatosis model simulating activated de novo lipogenesis in MAFLD patients.

Kim W, Li M, Jin H, ..., Zhang C, Mardinoglu A

iScience 26 (10) 107727 [2023-10-20; online 2023-08-25]

Adil Mardinoglu SciLifeLab Fellow

Evolutionary consequences of genomic deletions and insertions in the woolly mammoth genome.

van der Valk T, Dehasque M, Chacón-Duque JC, ..., Díez-Del-Molino D, Dalén L

iScience 25 (8) 104826 [2022-08-19; online 2022-08-01]

DDLS Fellow Tom van der Valk

Genome-scale metabolic modelling of the human gut microbiome reveals changes in the glyoxylate and dicarboxylate metabolism in metabolic disorders.

Proffitt C, Bidkhori G, Lee S, ..., Moyes DL, Shoaie S

iScience 25 (7) 104513 [2022-07-15; online 2022-06-02]

Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow

A network-based approach reveals the dysregulated transcriptional regulation in non-alcoholic fatty liver disease.

Yang H, Arif M, Yuan M, ..., Zhang C, Mardinoglu A

iScience 24 (11) 103222 [2021-11-19; online 2021-10-05]

Adil Mardinoglu SciLifeLab Fellow

Stratification of patients with clear cell renal cell carcinoma to facilitate drug repositioning.

Li X, Kim W, Juszczak K, ..., Zhang C, Mardinoglu A

iScience 24 (7) 102722 [2021-07-23; online 2021-06-12]

Adil Mardinoglu SciLifeLab Fellow

Acute kidney injury leading to CKD is associated with a persistence of metabolic dysfunction and hypertriglyceridemia

Harzandi A, Lee S, Bidkhori G, ..., Shoaie S, Sharpe CC

iScience 24 (2) 102046 [2021-02-00; online 2021-02-00]

Saeed Shoaie SciLifeLab Fellow

Low Shear Stress Increases Recombinant Protein Production and High Shear Stress Increases Apoptosis in Human Cells.

Zhan C, Bidkhori G, Schwarz H, ..., Rockberg J, Chotteau V

iScience 23 (11) 101653 [2020-11-20; online 2020-10-07]

Adil Mardinoglu SciLifeLab Fellow

Current Status of COVID-19 Therapies and Drug Repositioning Applications.

Altay O, Mohammadi E, Lam S, ..., Uhlen M, Mardinoglu A

iScience 23 (7) 101303 [2020-07-24; online 2020-06-20]

Adil Mardinoglu SciLifeLab Fellow