Leveraging circulating microbial DNA for early cancer detection.

Kataria R, Shoaie S, Grigoriadis A, Wan JCM

Trends Cancer 9 (11) 879-882 [2023-11-00; online 2023-09-01]

Microbial cell-free DNA (microbial cfDNA) offers a minimally invasive approach for profiling the microbiome. Despite technical and biological challenges, the potential of microbial cfDNA for cancer detection is increasingly being evaluated using deep sequencing, novel laboratory approaches, and computational methods. Targeting the microbiome using liquid biopsies could improve early cancer detection.

PubMed 37659908

DOI 10.1016/j.trecan.2023.08.001

Crossref 10.1016/j.trecan.2023.08.001

pmc: PMC10873208
pii: S2405-8033(23)00157-7


Publications 9.5.1