Fredrik Edfors

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DDLS Fellow: Precision medicine and diagnostics

Primary: Shown in the list of current labels.

Year 2026

PubMed DOI Crossref
Proteome-scale autoantibody profiling in PSC: Associations with clinical phenotypes and evidence for neuroendocrine deregulations.
Cornillet M, Båve AL, Sun D, ..., Halfvarson J, Bergquist A
JHEP Rep 8 (3) 101719 [2026-03-00; online 2025-12-23]
DDLS Fellow Fredrik Edfors

Year 2025

PubMed DOI Crossref
Systems analysis of clinical malaria reveals proteomic perturbation and innate-adaptive crosstalk linked to disease severity.
Lautenbach MJ, Wyss K, Yman V, ..., Sundling C, Färnert A
Immunity 58 (8) 2120-2136.e5 [2025-08-12; online 2025-07-14]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
A resource for whole-body gene expression map of human tissues based on integration of single cell and bulk transcriptomics.
Shi M, Méar L, Karlsson M, ..., Uhlén M, Zhang C
Genome Biol. 26 (1) 152 [2025-06-03; online 2025-06-03]
Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow
DOI Crossref
Advancing Chronic Liver Disease Diagnoses: Targeted Proteomics for the Non-Invasive Detection of Fibrosis
Villanueva Raisman A, Kotol D, Altay O, ..., Zeybel M, Edfors F
Livers 5 (1) 2 [2025-01-14; online 2025-01-14]
Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow

Year 2024

PubMed DOI Crossref
The Circulating Proteome─Technological Developments, Current Challenges, and Future Trends.
Geyer PE, Hornburg D, Pernemalm M, ..., Deutsch EW, Schwenk JM
J. Proteome Res. 23 (12) 5279-5295 [2024-12-06; online 2024-10-31]
DDLS Fellow Fredrik Edfors
DOI Crossref
Longitudinal analysis of genetic and environmental interplay in human metabolic profiles and the implication for metabolic health
Wang J, Zenere A, Wang X, ..., Uhlén M, Zhong W
- - (-) - [2024-09-24; online 2024-09-24]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
Longitudinal Exposomics in a Multiomic Wellness Cohort Reveals Distinctive and Dynamic Environmental Chemical Mixtures in Blood.
Sdougkou K, Papazian S, Bonnefille B, ..., Martin LJ, Martin JW
Environ. Sci. Technol. 58 (37) 16302-16315 [2024-09-17; online 2024-09-05]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
Characterization of reduced astrocyte creatine kinase levels in Alzheimer's disease.
Zheng T, Kotol D, Sjöberg R, ..., Edfors F, Mulder J
Glia 72 (9) 1590-1603 [2024-09-00; online 2024-06-10]
DDLS Fellow Fredrik Edfors
DOI Crossref
Longitudinal Exposomics in a Multiomic Wellness Cohort Reveals Distinctive and Dynamic Environmental Chemical Mixtures in Blood
Sdougkou K, Papazian S, Bonnefille B, ..., Martin LJ, Martin JW
- - (-) - [2024-04-17; online 2024-04-17]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
Patient-Centric Quantitative Microsampling for Accurate Determination of Urine Albumin to Creatinine Ratio (UACR) in a Clinical Setting.
Löfgren L, von Euler Chelpin M, Bhat M, ..., Davidsson P, Miliotis T
J Appl Lab Med 9 (2) 329-341 [2024-03-01; online 2023-12-19]
DDLS Fellow Fredrik Edfors

Year 2023

PubMed DOI Crossref
Author Correction: Elevated plasma complement factor H related 5 protein is associated with venous thromboembolism.
Iglesias MJ, Sanchez-Rivera L, Ibrahim-Kosta M, ..., Trégouët DA, Odeberg J
Nat Commun 14 (1) 7752 [2023-11-27; online 2023-11-27]
DDLS Fellow Fredrik Edfors
DOI Crossref
Blood Proteins are Associated with Aneurysm Growth in Men with Screening Detected Abdominal Aortic Aneurysm
Siika A, Edfors F, Obeberg J, ..., Hultgren R, Roy J
Aorta (Stamford) 11 (05) 1-18 [2023-10-00; online 2024-06-11]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
Metabolite interactions in the bacterial Calvin cycle and implications for flux regulation.
Sporre E, Karlsen J, Schriever K, ..., Edfors F, Hudson EP
Commun Biol 6 (1) 947 [2023-09-18; online 2023-09-18]
DDLS Fellow Fredrik Edfors Paul Hudson SciLifeLab Fellow
PubMed DOI Crossref
Assessing the Role of Trypsin in Quantitative Plasma and Single-Cell Proteomics toward Clinical Application.
Woessmann J, Petrosius V, Üresin N, ..., Edfors F, Schoof EM
Anal. Chem. 95 (36) 13649-13658 [2023-09-12; online 2023-08-28]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
Next generation pan-cancer blood proteome profiling using proximity extension assay.
Álvez MB, Edfors F, von Feilitzen K, ..., Fagerberg L, Uhlén M
Nat Commun 14 (1) 4308 [2023-07-18; online 2023-07-18]
Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow
PubMed DOI Crossref
Orthogonal proteomics methods warrant the development of Duchenne muscular dystrophy biomarkers.
Johansson C, Hunt H, Signorelli M, ..., Uhlén M, Szigyarto CA
Clin Proteomics 20 (1) 23 [2023-06-12; online 2023-06-12]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
Elevated plasma complement factor H related 5 protein is associated with venous thromboembolism.
Iglesias MJ, Sanchez-Rivera L, Ibrahim-Kosta M, ..., Trégouët DA, Odeberg J
Nat Commun 14 (1) 3280 [2023-06-07; online 2023-06-07]
DDLS Fellow Fredrik Edfors
DOI Crossref
Assessing the role of trypsin in quantitative plasma- and single-cell proteomics towards clinical application
Woessmann J, Petrosius V, Üresin N, ..., Edfors F, Schoof EM
- - (-) - [2023-05-26; online 2023-05-26]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
Targeted proteomics using stable isotope labeled protein fragments enables precise and robust determination of total apolipoprotein(a) in human plasma.
Hober A, Rekanovic M, Forsström B, ..., Edfors F, Miliotis T
PLoS ONE 18 (2) e0281772 [2023-02-15; online 2023-02-15]
DDLS Fellow Fredrik Edfors
DOI Crossref
Genome-Wide Annotation of the Human Protein-Coding Genes Using Co-Expression Clustering
Bueno Álvez M, Karlsson M, Shi M, ..., Fagerberg L, Lindskog C
- - (-) - [2023-00-00; online 2023-00-00]
Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow

Year 2022

DOI Crossref
Orthogonal proteomics methods warrants development of Duchenne Muscular Dystrophy biomarkers
Johansson C, Hunt H, Signorelli M, ..., Uhlén M, Szigyarto CAK
- - (-) - [2022-12-05; online 2022-12-05]
DDLS Fellow Fredrik Edfors
DOI Crossref
Next generation pan-cancer blood proteome profiling using proximity extension assay
Uhlen M, Álvez MB, Edfors F, ..., Pontén F, Fagerberg L
- - (-) - [2022-11-01; online 2022-11-01]
Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow
PubMed DOI Crossref
Addressing the Protease Bias in Quantitative Proteomics.
Woessmann J, Kotol D, Hober A, Uhlén M, Edfors F
J. Proteome Res. 21 (10) 2526-2534 [2022-10-07; online 2022-08-31]
DDLS Fellow Fredrik Edfors
DOI Crossref
Genome-wide single cell annotation of the human protein-coding genes
Karlsson M, Álvez MB, Shi M, ..., Fagerberg L, Uhlén M
- - (-) - [2022-08-04; online 2022-08-04]
Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow
PubMed DOI Crossref
Harnessing secretory pathway differences between HEK293 and CHO to rescue production of difficult to express proteins.
Malm M, Kuo CC, Barzadd MM, ..., Hatton D, Rockberg J
Metab. Eng. 72 (-) 171-187 [2022-07-00; online 2022-03-14]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
Enhanced metabolism and negative regulation of ER stress support higher erythropoietin production in HEK293 cells.
Saghaleyni R, Malm M, Moruzzi N, ..., Robinson JL, Rockberg J
Cell Reports 39 (11) 110936 [2022-06-14; online 2022-06-16]
Aleksej Zelezniak DDLS Fellow Fredrik Edfors SciLifeLab Fellow
DOI Crossref
Metabolite interactions in the bacterial Calvin cycle and implications for flux regulation
Sporre E, Karlsen J, Schriever K, ..., Edfors F, Hudson EP
- - (-) - [2022-03-15; online 2022-03-15]
DDLS Fellow Fredrik Edfors Paul Hudson SciLifeLab Fellow
PubMed DOI Crossref
Proteomics in thrombosis research.
Edfors F, Iglesias MJ, Butler LM, Odeberg J
Res Pract Thromb Haemost 6 (3) e12706 [2022-03-00; online 2022-04-25]
DDLS Fellow Fredrik Edfors

Year 2021

PubMed DOI Crossref
Next generation plasma proteome profiling of COVID-19 patients with mild to moderate symptoms.
Zhong W, Altay O, Arif M, ..., Uhlen M, Fagerberg L
EBioMedicine 74 (-) 103723 [2021-12-00; online 2021-11-27]
Adil Mardinoglu DDLS Fellow Fredrik Edfors Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Rapid and sensitive detection of SARS-CoV-2 infection using quantitative peptide enrichment LC-MS analysis.
Hober A, Tran-Minh KH, Foley D, ..., Engstrand L, Edfors F
Elife 10 (-) - [2021-11-08; online 2021-11-08]
DDLS Fellow Fredrik Edfors
DOI Crossref
Author response: Rapid and sensitive detection of SARS-CoV-2 infection using quantitative peptide enrichment LC-MS analysis
Hober A, Tran-Minh KH, Foley D, ..., Engstrand L, Edfors F
- - (-) - [2021-10-19; online 2021-10-19]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
Targeted proteomics analysis of plasma proteins using recombinant protein standards for addition only workflows.
Kotol D, Hober A, Strandberg L, ..., Uhlén M, Edfors F
BioTechniques 71 (3) 473-483 [2021-09-00; online 2021-08-25]
DDLS Fellow Fredrik Edfors
DOI Crossref
Harnessing secretory pathway differences between HEK293 and CHO to rescue production of difficult to express proteins
Malm M, Kuo CC, Barzadd MM, ..., Hatton D, Rockberg J
- - (-) - [2021-08-17; online 2021-08-17]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
A single-cell type transcriptomics map of human tissues.
Karlsson M, Zhang C, Méar L, ..., Uhlén M, Lindskog C
Sci Adv 7 (31) - [2021-07-00; online 2021-07-28]
Adil Mardinoglu DDLS Fellow Fredrik Edfors Muhammad Arif SciLifeLab Fellow
DOI Crossref
Next generation plasma proteome profiling of COVID-19 patients with mild to moderate symptoms
Zhong W, Altay O, Arif M, ..., Uhlén M, Fagerberg L
- - (-) - [2021-06-21; online 2021-06-21]
Adil Mardinoglu DDLS Fellow Fredrik Edfors Muhammad Arif SciLifeLab Fellow
DOI Crossref
Rapid and Sensitive Detection of SARS-CoV-2 Infection Using Quantitative Peptide Enrichment LC-MS Analysis
Hober A, Hua TMK, Foley D, ..., Engstrand L, Edfors F
- - (-) - [2021-06-04; online 2021-06-04]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
Next generation plasma proteome profiling to monitor health and disease.
Zhong W, Edfors F, Gummesson A, ..., Fagerberg L, Uhlén M
Nat Commun 12 (1) 2493 [2021-05-03; online 2021-05-03]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
Longitudinal plasma protein profiling of newly diagnosed type 2 diabetes.
Gummesson A, Björnson E, Fagerberg L, ..., Uhlén M, Bergström G
EBioMedicine 63 (-) 103147 [2021-01-00; online 2020-12-03]
DDLS Fellow Fredrik Edfors

Year 2020

PubMed DOI Crossref
Longitudinal Plasma Protein Profiling Using Targeted Proteomics and Recombinant Protein Standards.
Kotol D, Hunt H, Hober A, ..., Uhlén M, Edfors F
J. Proteome Res. 19 (12) 4815-4825 [2020-12-04; online 2020-09-04]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
Profiles of histidine-rich glycoprotein associate with age and risk of all-cause mortality.
Hong MG, Dodig-Crnković T, Chen X, ..., Magnusson PK, Schwenk JM
Life Sci. Alliance 3 (10) - [2020-10-00; online 2020-07-31]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
High throughput generation of a resource of the human secretome in mammalian cells.
Tegel H, Dannemeyer M, Kanje S, ..., Uhlén M, Hober S
N Biotechnol 58 (-) 45-54 [2020-09-25; online 2020-06-02]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
Integration of molecular profiles in a longitudinal wellness profiling cohort.
Tebani A, Gummesson A, Zhong W, ..., Uhlen M, Fagerberg L
Nat Commun 11 (1) 4487 [2020-09-08; online 2020-09-08]
Adil Mardinoglu DDLS Fellow Fredrik Edfors Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
SAMHD1 phosphorylation and cytoplasmic relocalization after human cytomegalovirus infection limits its antiviral activity.
De Meo S, Dell'Oste V, Molfetta R, ..., Santoni A, Cerboni C
PLoS Pathog 16 (9) e1008855 [2020-09-00; online 2020-09-28]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
Facets of individual-specific health signatures determined from longitudinal plasma proteome profiling.
Dodig-Crnković T, Hong MG, Thomas CE, ..., Uhlén M, Schwenk JM
EBioMedicine 57 (-) 102854 [2020-07-00; online 2020-07-03]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
Whole-genome sequence association analysis of blood proteins in a longitudinal wellness cohort.
Zhong W, Gummesson A, Tebani A, ..., Fagerberg L, Uhlén M
Genome Med 12 (1) 53 [2020-06-23; online 2020-06-23]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
National Cancer Institute Think-Tank Meeting Report on Proteomic Cartography and Biomarkers at the Single-Cell Level: Interrogation of Premalignant Lesions.
Kagan J, Moritz RL, Mazurchuk R, ..., Smith RD, Srivastava S
J. Proteome Res. 19 (5) 1900-1912 [2020-05-01; online 2020-04-02]
DDLS Fellow Fredrik Edfors
DOI Crossref
Facets of individual-specific health signatures determined from longitudinal plasma proteome profiling
Dodig-Crnković T, Hong MG, Thomas CE, ..., Uhlén M, Schwenk JM
- - (-) - [2020-03-15; online 2020-03-15]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
An atlas of the protein-coding genes in the human, pig, and mouse brain.
Sjöstedt E, Zhong W, Fagerberg L, ..., Uhlén M, Mulder J
Science (New York, N.Y.) 367 (6482) eaay5947 [2020-03-06; online 2020-03-07]
Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow

Year 2019

PubMed DOI Crossref
A genome-wide transcriptomic analysis of protein-coding genes in human blood cells.
Uhlen M, Karlsson MJ, Zhong W, ..., Fagerberg L, Brodin P
Science (New York, N.Y.) 366 (6472) eaax9198 [2019-12-20; online 2019-12-21]
Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow
PubMed DOI Crossref
Absolute Quantification of Apolipoproteins Following Treatment with Omega-3 Carboxylic Acids and Fenofibrate Using a High Precision Stable Isotope-labeled Recombinant Protein Fragments Based SRM Assay.
Hober A, Edfors F, Ryaboshapkina M, ..., Oscarsson J, Miliotis T
Mol. Cell Proteomics 18 (12) 2433-2446 [2019-12-00; online 2019-10-07]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
The human secretome.
Uhlén M, Karlsson MJ, Hober A, ..., Fagerberg L, Sivertsson Å
Sci Signal 12 (609) eaaz0274 [2019-11-26; online 2019-11-26]
Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow
PubMed DOI Crossref
Systematic Development of Sandwich Immunoassays for the Plasma Secretome.
Häussler RS, Bendes A, Iglesias M, ..., Qundos U, Schwenk JM
Proteomics 19 (15) e1900008 [2019-08-00; online 2019-07-22]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
Screening a Resource of Recombinant Protein Fragments for Targeted Proteomics.
Edfors F, Forsström B, Vunk H, ..., Schwenk JM, Uhlen M
J. Proteome Res. 18 (7) 2706-2718 [2019-07-05; online 2019-06-07]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
Development of parallel reaction monitoring assays for cerebrospinal fluid proteins associated with Alzheimer's disease.
Andersson A, Remnestål J, Nellgård B, ..., Nilsson P, Fredolini C
Clin Chim Acta 494 (-) 79-93 [2019-07-00; online 2019-03-09]
DDLS Fellow Fredrik Edfors
DOI Crossref
Systematic Development of Sandwich Immunoassays for the Plasma Secretome
Häussler RS, Bendes A, Iglesias M, ..., Qundos U, Schwenk JM
- - (-) - [2019-01-08; online 2019-01-08]
DDLS Fellow Fredrik Edfors

Year 2018

DOI Crossref
The human secretome – the proteins secreted from human cells
Uhlen M, Tegel H, Sivertsson Å, ..., Schiavone LH, Hober S
- - (-) - [2018-11-26; online 2018-11-26]
Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow
DOI Crossref
Screening a Resource of Recombinant Protein Fragments for Targeted Proteomics
Edfors F, Forsström B, Vunk H, ..., Schwenk JM, Uhlen M
- - (-) - [2018-11-19; online 2018-11-19]
DDLS Fellow Fredrik Edfors
DOI Crossref
Profiles of circulating histidine-rich glycoprotein associate with chronological age and risk of all-cause mortality
Hong MG, Dodig-Crnković T, Chen X, ..., Magnusson PKE, Schwenk JM
- - (-) - [2018-11-09; online 2018-11-09]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
Growth of Cyanobacteria Is Constrained by the Abundance of Light and Carbon Assimilation Proteins.
Jahn M, Vialas V, Karlsen J, ..., Käll L, Hudson EP
Cell Reports 25 (2) 478-486.e8 [2018-10-09; online 2018-10-12]
DDLS Fellow Fredrik Edfors Paul Hudson SciLifeLab Fellow
PubMed DOI Crossref
Enhanced validation of antibodies for research applications.
Edfors F, Hober A, Linderbäck K, ..., Forsström B, Uhlen M
Nat Commun 9 (1) 4130 [2018-10-08; online 2018-10-08]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
High Cell Density Perfusion Culture has a Maintained Exoproteome and Metabolome.
Zamani L, Lundqvist M, Zhang Y, ..., Rockberg J, Chotteau V
Biotechnol J 13 (10) e1800036 [2018-10-00; online 2018-07-13]
Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow
PubMed DOI Crossref
A Protein Standard That Emulates Homology for the Characterization of Protein Inference Algorithms.
The M, Edfors F, Perez-Riverol Y, ..., Forsström B, Käll L
J. Proteome Res. 17 (5) 1879-1886 [2018-05-04; online 2018-04-16]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
Targeting CDK2 overcomes melanoma resistance against BRAF and Hsp90 inhibitors.
Azimi A, Caramuta S, Seashore-Ludlow B, ..., Uhlen M, Maddalo G
Mol Syst Biol 14 (3) e7858 [2018-03-05; online 2018-03-05]
DDLS Fellow Fredrik Edfors

Year 2017

DOI Crossref
A protein standard that emulates homology for the characterization of protein inference algorithms
The M, Edfors F, Perez-Riverol Y, ..., Forsström B, Käll L
- - (-) - [2017-12-19; online 2017-12-19]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
A pathology atlas of the human cancer transcriptome.
Uhlen M, Zhang C, Lee S, ..., Mardinoglu A, Ponten F
Science (New York, N.Y.) 357 (6352) eaan2507 [2017-08-18; online 2017-08-19]
Adil Mardinoglu Affiliated researcher DDLS Fellow Fredrik Edfors Muhammad Arif SciLifeLab Fellow

Year 2016

PubMed DOI Crossref
Gene-specific correlation of RNA and protein levels in human cells and tissues.
Edfors F, Danielsson F, Hallström BM, ..., Forsström B, Uhlén M
Mol Syst Biol 12 (10) 883 [2016-10-20; online 2016-10-20]
DDLS Fellow Fredrik Edfors
SciLifeLab Data Centre
Publications 9.5.1