Compartmentalizing damaged DNA: A double-edged sword.

Georgiades E, Crosetto N, Bienko M

Mol. Cell 84 (1) 12-13 [2024-01-04; online 2024-01-06]

A recent publication in Nature by Arnould et al.1 describes a novel chromatin compartment, termed "damaged" or "D compartment," that facilitates the repair of DNA double-strand breaks but also increases the risk of potentially oncogenic translocation formation.

PubMed 38181754

DOI 10.1016/j.molcel.2023.12.001

Crossref 10.1016/j.molcel.2023.12.001

pii: S1097-2765(23)01020-1


Publications 9.5.1