Publications 2025

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1327 publications

DOI Crossref
Drugs that act on both GPCRs and kinases: Potentiation of effects, side effects and general aspects of drug pleiotropy
Ljunggren H, Sokolov A, Ballante F, ..., Jonsson J, Schiöth HB
- - (-) - [2025-12-31; online 2025-12-31]
PubMed DOI Crossref
Template-based RNA structure prediction advanced through a blind code competition.
Lee Y, He S, Oda T, ..., Zhang S, Das R
bioRxiv - (-) - [2025-12-30; online 2025-12-30]
DOI Crossref
Targeted proteome analysis of extracellular vesicles from gastric cancer cell lines
Sinha TK, Harinck GM, Doulabi EM, ..., Shen Q, Kamali-Moghaddam M
BMC Methods 2 (1) - [2025-12-29; online 2025-12-29]
PubMed DOI Crossref
Plasma protein profiling predicts cancer in patients with non-specific symptoms.
Wannberg F, Álvez MB, Qvick A, ..., Rosell A, Thålin C
Nat Commun 17 (1) 151 [2025-12-29; online 2025-12-29]
PubMed DOI Crossref
Exploratory study linking plasma proteomics to cardiotoxicity in Hodgkin lymphoma.
Ulfstedt JM, Risebro R, Freyhult E, ..., Enblad G, Molin D
Cardiooncology 12 (1) 13 [2025-12-26; online 2025-12-26]
DOI Crossref
Timing matters: exon skipping therapy is most effective when initiated early in a mouse model of Duchenne muscular dystrophy
Stenler S, Huang J, van Westering TLE, ..., Wood MJA, Roberts TC
- - (-) - [2025-12-25; online 2025-12-25]
DOI Crossref
The collision of two genomes threatens global food security
North HL, Montejo-Kovacevich G, Amado D, ..., Omoto C, Jiggins CD
- - (-) - [2025-12-25; online 2025-12-25]
Gabriela Montejo-Kovacevich SciLifeLab Fellow
PubMed DOI Crossref
Retrospective validation of an artificial intelligence system for diagnostic assessment of prostate biopsies on the ProMort cohort: study protocol.
Ji X, Zelic R, Aspegren O, ..., Akre O, Kartasalo K
BMJ Open 15 (12) e111361 [2025-12-24; online 2025-12-24]
DDLS Fellow Kimmo Kartasalo
PubMed DOI Crossref
Maturation of human intestinal epithelial cell layers fortifies the apical surface against Salmonella attack.
van Rijn JM, Lopes ACC, Dienhart FSV, ..., Di Martino ML, Sellin ME
Cell Reports 44 (12) 116579 [2025-12-23; online 2025-11-21]
Mikael Sellin SciLifeLab Fellow
DOI Crossref
Data availability impacts the predictive accuracy of pressure-based biodiversity models
Nyström J, Smith JR, Mandle L, ..., Schön TB, Andermann T
- - (-) - [2025-12-23; online 2025-12-23]
DDLS Fellow Tobias Andermann
PubMed DOI Crossref
Accelerating SCF Orbital Optimization with S-GEK/RVO: Efficient Subspace Compression and Robust Convergence.
Fdez Galván I, Weßling D, Lindh R
J Chem Theory Comput 21 (24) 12674-12685 [2025-12-23; online 2025-12-07]
PubMed DOI Crossref
The gut microbiome in early pregnancy is associated with the severity of nausea and vomiting: a nested case‒control study.
González-Valdivia C, Tong B, Hjalmarsson S, ..., Brusselaers N, Hugerth LW
Gut Microbes Rep 3 (1) 2603861 [2025-12-22; online 2025-12-22]
DDLS Fellow Luisa Hugerth
PubMed DOI Crossref
LIPA, a risk locus for coronary artery disease: decoding the variant-to-function relationship.
Li F, Flynn E, Ha P, ..., Lappalainen T, Zhang H
Eur. Heart J. 46 (48) 5273-5288 [2025-12-22; online 2025-08-19]
DOI Crossref
The effect of genome organisation on selection efficiency in two contrasted plant species
James JE, Lascoux M
- - (-) - [2025-12-20; online 2025-12-20]
DDLS Fellow Jennifer James
PubMed DOI Crossref
Protocol for image-based monitoring of de novo RNA synthesis at DNA double-strand breaks in human cell lines.
Pappas G, Gram HH, Bartek J, Galanos P
STAR Protoc 6 (4) 104157 [2025-12-19; online 2025-10-22]
PubMed DOI Crossref
Protocol for generation of endothelial cells from human-derived iPSCs and integration into mouse brain explants.
Erzar I, Noll N, Lugano R, ..., Arce M, Magnusson PU
STAR Protoc 6 (4) 104239 [2025-12-19; online 2025-12-05]
PubMed DOI Crossref
OAS1 and OAS3 genetic variants enhance inflammatory responses to SARS-CoV-2.
DeDiego ML, López-Fernández-Sobrino R, Pedragosa J, ..., Pérez-Tur J, Planas AM
iScience 28 (12) 113966 [2025-12-19; online 2025-11-11]
PubMed DOI Crossref
Insight into Malt1 activation mechanism through synergetic approach of AlphaFold, MD Simulation and NMR dynamic analyses.
Lesovoy D, Agback T, Roshchin K, ..., Orekhov V, Agback P
bioRxiv - (-) - [2025-12-19; online 2025-12-19]
PubMed DOI Crossref
Development of DARPin T cell engagers for specific targeting of tumor-associated HLA/peptide complexes.
Venetz-Arenas N, Schulte T, Müller S, ..., Walser M, Achour A
iScience 28 (12) 113926 [2025-12-19; online 2025-11-03]
PubMed DOI Crossref
ZEB1, a novel junctional adhesion molecule A regulator, impacts sensitivity of pancreatic cancer-associated fibroblasts to reovirus.
Dam N, Harryvan TJ, Dang H, ..., Hawinkels LJAC, Kemp V
Mol Ther Oncol 33 (4) 201071 [2025-12-18; online 2025-10-17]
PubMed DOI Crossref
Improved Identification of Large-effect Rare Genetic Variants using Haplotype Aggregated Allele-specific Expression Data.
Ganapathy KR, Broly M, Silverstein S, ..., Lappalainen T, Mohammadi P
medRxiv - (-) - [2025-12-18; online 2025-12-18]
PubMed DOI Crossref
A human pan-disease blood atlas of the circulating proteome.
Álvez MB, Bergström S, Kenrick J, ..., Edfors F, Uhlén M
Science (New York, N.Y.) 390 (6779) eadx2678 [2025-12-18; online 2025-12-18]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Prenatal Exposure to Phthalates, Bisphenols and Their Mixtures and Early Childhood Allergic Conditions and Asthma: Results from the APrON Cohort.
Bartram E, England-Mason G, Martin JW, ..., Soomro MH, APrON Study Team
Int J Environ Res Public Health 22 (12) - [2025-12-17; online 2025-12-17]
PubMed DOI Crossref
Blood-based biomarkers of Alzheimer's disease and olfactory decline over 15 years in older adults.
Ekström I, Vetrano DL, Valletta M, ..., Grande G, Laukka EJ
Geroscience - (-) - [2025-12-17; online 2025-12-17]
DOI Crossref
The vaginal microbiota and gynaecological health study - VaMiGyn - description of a population-based Swedish cohort
Norenhag J, Edfeldt G, Stålberg K, ..., Engstrand L, Olovsson M
npj Womens Health 3 (1) - [2025-12-16; online 2025-12-16]
DDLS Fellow Luisa Hugerth
PubMed DOI Crossref
SARS-CoV-2 Spike Protein Amyloid Fibrils Impair Fibrin Formation and Fibrinolysis.
Westman H, Hammarström P, Nyström S
Biochemistry 64 (24) 4818-4829 [2025-12-16; online 2025-11-26]
PubMed DOI Crossref
Macrophages as central mediators of sympathetic neuro-immune interplay in autoimmunity.
Muntjewerff EM, Josyula VS, Lehmair F, Christoffersson G
Front Immunol 16 (-) 1654382 [2025-12-16; online 2025-12-16]
Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
Vascular Bed-Specific Endothelial Dysfunction and Age-Dependent Circadian Hypertension in Mice Lacking the Resolvin D2 Receptor GPR18.
de Moudt S, Sitek B, Bar A, ..., Mercier N, Bäck M
FASEB J. 39 (23) e71245 [2025-12-15; online 2025-12-01]
PubMed DOI Crossref
Sudden Arrhythmic Death Syndrome in the Young: Risk Factors are Identifiable Prior to Sudden Cardiac Arrest.
Torell MF, Svennblad B, Wisten A, ..., Stattin EL, Börjesson M
Am J Cardiol 257 (-) 193-199 [2025-12-15; online 2025-10-09]
PubMed DOI Crossref
Minimal structural perturbation of Histatin 5 in crowded environments: Insights from small-angle X-ray scattering, dynamic light scattering, and computer simulations.
Fagerberg E, Holmqvist P, Lenton S, Pernot P, Skepö M
J Colloid Interface Sci 700 (Pt 1) 138310 [2025-12-15; online 2025-07-07]
PubMed DOI Crossref
PDGFRß targeted positron emission tomography as a non-invasive biomarker for activated hepatic stellate cells: lasts steps before clinical translation.
Yashaswini CN, Mitran B, Papadopoulos N, ..., Friedman SL, Eriksson O
EJNMMI Radiopharm Chem 10 (1) 80 [2025-12-13; online 2025-12-13]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Leveraging network motifs to improve artificial neural networks.
Zhang H, Yang CH, Zenil H, ..., Kiani NA, Tegnér JN
Nat Commun 16 (1) 11495 [2025-12-13; online 2025-12-13]
PubMed DOI Crossref
Can we infer excitation-inhibition balance from the spectrum of population activity?
Chakravarty K, Roy S, Sinha A, Kumar A
Commun Biol 9 (1) 51 [2025-12-13; online 2025-12-13]
PubMed DOI Crossref
Widespread potential for phototrophy and convergent reduction of lifecycle complexity in the dimorphic order Caulobacterales.
Hallgren J, Dharamshi JE, Rodríguez-Gijón A, ..., Garcia SL, Jonas K
Nat Commun 16 (1) 11003 [2025-12-12; online 2025-12-12]
Kristina Jonas Sarahi Garcia SciLifeLab Fellow
PubMed DOI Crossref
Mapping the circulating proteome across neurodegeneration: A harmonized, consortium-scale framework for uncovering molecular pathophysiology.
Finney CA, An L, Winchester LM, ..., Saloner R, Shvetcov A
bioRxiv - (-) - [2025-12-12; online 2025-12-12]
PubMed DOI Crossref
The Advanced Therapies model of Lund an integrated approach to accelerate access for many patients.
Helenius G, Jovinge S, Falk A
Mol Ther Methods Clin Dev 33 (4) 101637 [2025-12-11; online 2025-11-25]
DOI Crossref
RNA BaseCode: Long-Read RNA Sequences with Short-Read Accuracy
Hendriks GJ, Larsson AJM, de Castroviejo Teba PR, ..., Ziegenhain C, Sandberg R
- - (-) - [2025-12-11; online 2025-12-11]
PubMed DOI Crossref
Inter- and intra-individual differences in brain sex map to neuroendocrine profiles.
Bon GM, Kimmig AS, Comasco E, Derntl B, Kaufmann T
bioRxiv - (-) - [2025-12-11; online 2025-12-11]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Meat Intake in Relation to Metabolomic Signatures, Gut Microbiome, and Cardiovascular Disease Risk: A Narrative Review.
Yoshida E, Arage G, Rašo LM, ..., Larsson SC, Ahmad S
Nutr Rev - (-) - [2025-12-10; online 2025-12-10]
PubMed DOI Crossref
Insulin-regulated aminopeptidase inhibitor C9 restores cellular activity in methadone-damaged primary cell cultures.
Stam F, Bjurling S, Nylander E, ..., Grönbladh A, Hallberg M
Neurosci. Lett. 869 (-) 138415 [2025-12-10; online 2025-10-10]
PubMed DOI Crossref
Chromosome-level assembly of the club-legged grasshopper (Gomphocerus sibiricus) genome.
Palacios-Gimenez OM, Varma M, Cheng X, ..., Suh A, Schielzeth H
G3 15 (12) - [2025-12-10; online 2025-10-01]
PubMed DOI Crossref
A morphology-based machine learning model for scoring epithelial-mesenchymal plasticity using organelle dynamics.
Slager J, Gatto F, Frey B, ..., Parniewska MM, Fuxe J
Commun Biol 9 (1) 59 [2025-12-10; online 2025-12-10]
PubMed DOI Crossref
A co-speciation dilemma and a lifestyle transition with genomic consequences in Wolbachia of Neotropical Drosophila.
Papachristos K, Miller WJ, Klasson L
BMC Genomics 27 (1) 41 [2025-12-10; online 2025-12-10]
PubMed DOI Crossref
Ultra-large virtual screening unveils potent agonists of the neuromodulatory orphan receptor GPR139.
Cabeza de Vaca I, Trapkov B, Shen L, ..., Hauser AS, Carlsson J
Nat Commun 17 (1) 129 [2025-12-09; online 2025-12-09]
Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Integrating extensive functional annotations and multiomics of cattle enhances climate resilience prediction and mapping.
Xiang R, Breen E, Bolormaa S, ..., Chamberlain AJ, Goddard ME
Proc. Natl. Acad. Sci. U.S.A. 122 (49) e2514736122 [2025-12-09; online 2025-11-24]
PubMed DOI Crossref
Hair follicle gene expression profiling in the SubPopulations and InteRmediate Outcome Measures in COPD Study (SPIROMICS).
Buschur KL, Martorella M, Garcia-Flores R, ..., Barr RG, Lappalainen T
BMC Med Genomics 18 (1) 192 [2025-12-09; online 2025-12-09]
PubMed DOI Crossref
Discovery of Previously Unreported Per- and Polyfluoroalkyl Substances (PFAS) in Pooled Australian Human Serum Using Nontarget Analysis.
Dewapriya P, Nilsson S, Ghorbani Gorji S, ..., Kaserzon SL, Thomas KV
Environ. Sci. Technol. 59 (48) 26081-26091 [2025-12-09; online 2025-11-26]
DOI Crossref
A modular lentiviral system for multiplexed gene perturbation and functional analysis suggests interdependence of hormone receptors in breast cancer growth in vivo
Alam S, Matvienko D, Boström J, ..., Brisken C, Altun M
- - (-) - [2025-12-09; online 2025-12-09]
DOI Crossref
A Critical Review and Evaluation of Blood Microsampling Devices for Exposomics
Thiele S, Martin JW
Environ Sci Technol Lett 12 (12) 1595-1610 [2025-12-09; online 2025-11-07]
PubMed DOI Crossref
Pharmacological activation of p53 induces dose-dependent changes in endothelial cell fate during angiogenic sprouting.
Al-Radi O, Ingelshed K, Eichhorn L, ..., Lane DP, Kannan P
Cell Death Dis 16 (1) 883 [2025-12-08; online 2025-12-08]
PubMed DOI Crossref
Evolvability: progress and key questions
Pélabon C, Agudelo-Cantero GA, Araya Ajoy YG, ..., Walling C, Wright J
Bioscience 75 (12) 1042-1057 [2025-12-08; online 2025-09-09]
DDLS Fellow Lisandro Milocco
PubMed DOI Crossref
Tissue-resident microbiota impacts colorectal cancer progression and prognosis.
Shi Z, Ren H, Lin C, ..., Sjöblom T, Zhong H
Nat Commun 17 (1) 346 [2025-12-07; online 2025-12-07]
PubMed DOI Crossref
Predicting allergy and postpartum depression from an incomplete compositional microbiome.
Shternshis A, Tong B, Skalkidou A, ..., Hugerth LW, Singh P
BMC Genomics 26 (1) 1092 [2025-12-06; online 2025-12-06]
DDLS Fellow Luisa Hugerth Prashant Singh SciLifeLab Fellow
PubMed DOI Crossref
PLGA Nanoencapsulation Enhances Immunogenicity of Heat-Shocked Melanoma Tumor Cell Lysates.
Matheu KC, Araya BC, Diaz FT, ..., Salazar-Onfray F, Tittarelli A
Cells 14 (24) - [2025-12-06; online 2025-12-06]
DOI Crossref
Impact of fluctuating environments on the fitness and robustness of evolving laboratory and industrial Saccharomyces cerevisiae strains
Trivellin C, Ekman D, Persson K, ..., Olsson L, Desai MM
- - (-) - [2025-12-06; online 2025-12-06]
PubMed DOI Crossref
YAP-Induced Glycolysis Drives Fibroinflammation and Disrupts Fibroblast Fidelity.
Tsai CR, Liu L, Zhao Y, ..., Li X, Martin JF
Circ. Res. 137 (12) 1443-1458 [2025-12-05; online 2025-10-30]
PubMed DOI Crossref
Structural basis of specific lysine transport by Pseudomonas aeruginosa permease LysP.
Bicer D, Matsuoka R, Moumbock AFA, ..., Griese JJ, Nji E
Nat Commun 17 (1) 37 [2025-12-04; online 2025-12-04]
DOI Crossref
Safe-and-sustainable-by-design approach to polyesters from non-oestrogenic bisphenols
Margarita C, Pierozan P, Subramaniyan S, ..., Karlsson O, Lundberg H
Nat Sustain 9 (1) 86-95 [2025-12-04; online 2025-12-04]
Oskar Karlsson SciLifeLab Fellow
PubMed DOI Crossref
Evolving frontiers in bladder cancer immunotherapy: integrating BCG, immune checkpoints, viral vectors, nanotechnology, and CAR-based therapies.
Di Spirito A, Zuccolotto G, Tosi A, ..., Baci D, Mortara L
Front Cell Dev Biol 13 (-) 1719978 [2025-12-04; online 2025-12-04]
PubMed DOI Crossref
Evaluation of CD44v6-targeted radionuclide therapy on bone marrow, skin and esophageal epithelium using a novel internal dosimetry model.
Hemmingsson J, Nestor M, Mortensen AL, Frejd FY, Bernhardt P
Phys Med Biol 70 (23) - [2025-12-04; online 2025-12-04]
PubMed DOI Crossref
Microbial model communities exhibit widespread metabolic interdependencies.
Pacheco-Valenciana A, Tausch A, Veseli I, ..., Andersson AF, Garcia SL
Commun Biol 8 (1) 1752 [2025-12-03; online 2025-12-03]
Sarahi Garcia SciLifeLab Fellow
PubMed DOI Crossref
Trait- versus state- grey matter volume alterations in premenstrual dysphoric disorder.
Stiernman L, Dubol M, Sundström-Poromaa I, Bixo M, Comasco E
BMC Psychiatry 25 (1) 1139 [2025-12-02; online 2025-12-02]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Results of a non-randomized, open-label phase I study evaluating the novel immunomodulatory peptide TCP-25 for treatment of dystrophic epidermolysis bullosa.
Wallblom K, Holmgren K, Lundgren S, ..., Sonkoly E, Schmidtchen A
Orphanet J Rare Dis 21 (1) 4 [2025-12-02; online 2025-12-02]
DOI Crossref
Killing by Proximity
Zawacka JE
- - (-) - [2025-12-02; online 2025-12-02]
PubMed DOI Crossref
Growth hormone regulates the stem cell population in the growth plate.
Chu NTL, Zhou B, Heinonen JO, ..., Ohlsson C, Chagin AS
Proc. Natl. Acad. Sci. U.S.A. 122 (48) e2512316122 [2025-12-02; online 2025-11-25]
PubMed DOI Crossref
Engineered calcium-regulated affinity protein for efficient internalization and lysosomal toxin delivery.
Jönsson M, Möller M, Schierholz L, ..., Brismar H, Hober S
Proc. Natl. Acad. Sci. U.S.A. 122 (48) e2509081122 [2025-12-02; online 2025-11-25]
DOI Crossref
Engineered Fab glycosylation of a blood-brain barrier transporter single-chain variable fragment preserved functionality but did not impact anti-drug antibody formation
Hederoth G, Liu J, Godec A, ..., Rethi B, Hultqvist G
- - (-) - [2025-12-02; online 2025-12-02]
PubMed DOI Crossref
Characterization of five environmental phages infecting Escherichia coli K-12 isolated during a phage biology training course.
Shyrokova L, Egorov AA, Cole A, ..., Hauryliuk V, Johansson MJO
Microbiol Spectr 13 (12) e0227425 [2025-12-02; online 2025-11-06]
PubMed DOI Crossref
A deep learning-derived digital biomarker of dysglycemia and its association with genetic risk of type 2 diabetes.
Shao J, Pan Y, Xue J, ..., Feng H, Zhou K
NPJ Metab Health Dis 3 (1) 46 [2025-12-02; online 2025-12-02]
PubMed DOI Crossref
Transcriptomic Patterns in Adult and Pediatric Patients with IgA Nephropathy or IgA Vasculitis with Nephropathy.
Levin A, Schwarz A, van Hoef V, ..., Witasp A, Wernerson A
J. Am. Soc. Nephrol. 36 (12) 2392-2409 [2025-12-01; online 2025-07-01]
DOI Crossref
Tissue architecture and immune niches govern ctDNA release in colorectal cancer
Kühberger S, Sallinger K, Müller CT, ..., El-Heliebi A, Heitzer E
- - (-) - [2025-12-01; online 2025-12-01]
PubMed DOI Crossref
Structural diversity and conservation among CRESS-DNA bacilladnaviruses revealed through cryo-EM and computational modelling.
Gebhard LJ, Tomaru Y, Okamoto K, Munke A
Virol. J. 22 (1) 391 [2025-12-01; online 2025-12-01]
PubMed DOI Crossref
Occupational exposure to chemicals and particles and incidence of myocardial infarction-a nationwide cohort study in Sweden.
Grahn K, Lissåker C, Andersson T, ..., Albin M, Selander J
Environ. Res. 286 (Pt 1) 122783 [2025-12-01; online 2025-09-05]
PubMed DOI Crossref
Linker modifications in radiolabeled RM26-based antagonists to gastrin-releasing peptide receptor (GRPR) improved tracers' pharmacokinetics.
Bezverkhniaia E, Abouzayed A, Kanellopoulos P, ..., Rosenström U, Orlova A
Eur J Pharm Sci 215 (-) 107325 [2025-12-01; online 2025-10-13]
PubMed DOI Crossref
Hormonal Contraceptive Formulations and Breast Cancer Risk in Adolescents and Premenopausal Women.
Hadizadeh F, Koteci A, Karlsson T, Ek WE, Johansson Å
JAMA Oncol 11 (12) 1497-1506 [2025-12-01; online 2025-10-30]
PubMed DOI Crossref
Ga-68-Labeled Affibody Molecule-Based Radiopharmaceutical Targeting Platelet Derived Growth Factor Receptor Beta for Detection of Active Fibrosis in Patients with Myocardial Infarction.
Velikyan I, Grinnemo KH, Flodin V, ..., Korsgren O, Eriksson O
Pharmaceuticals (Basel, Switzerland) 18 (12) - [2025-12-01; online 2025-12-01]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Ca2+ signal dynamics in maturing ureteric bud- and collecting duct-derived organoid tubules.
Carrisoza-Gaytán R, Daily A, Wolf KJ, ..., Lewis JA, Satlin LM
Am. J. Physiol., Cell Physiol. 329 (6) C1842-C1856 [2025-12-01; online 2025-09-30]
PubMed DOI Crossref
Breast cancer risk during oral contraceptive use in women with high polygenic risk.
Chatsatourian C, Lo Faro V, Karlsson T, Hadizadeh F, Johansson Å
Breast Cancer Res. 27 (1) 215 [2025-12-01; online 2025-12-01]
PubMed DOI Crossref
Association Between Chronic Kidney Disease and Glaucoma: Results From the Lifelines Cohort Study and UK Biobank.
Liu W, Guo R, Wang S, ..., Snieder H, Jansonius NM
Invest. Ophthalmol. Vis. Sci. 66 (15) 17 [2025-12-01; online 2025-12-03]
PubMed DOI Crossref
All-optical strategies to minimize photobleaching in reversibly switchable fluorescent proteins.
Marín-Aguilera G, Pennacchietti F, Volpato A, ..., Widengren J, Testa I
Nat Commun 16 (1) 10843 [2025-12-01; online 2025-12-01]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
What is in a name? Rethinking SMUG1 in genome maintenance.
Rudolfova N, Skjetne AM, Montaldo NP, ..., Nilsen HL, Michel M
NAR Cancer 7 (4) zcaf050 [2025-12-00; online 2025-12-12]
PubMed DOI Crossref
Toward Process-Driven Research in Astrobiology: Stepping Away from the Binary Biogenicity Versus Abiogenicity Approach.
Borges SR, Schaible GA, Sagasti AJ, ..., Soares GG, Gangidine A
Astrobiology 25 (12) 822-828 [2025-12-00; online 2025-11-24]
DOI Crossref
The utility of combining deep learning with metabarcoding to model biodiversity dynamics at a national scale
Baggström A, Goodsell R, van Dijk L, ..., Tack AJM, Andermann T
Ecological Informatics 90 (-) 103318 [2025-12-00; online 2025-12-00]
DDLS Fellow Tobias Andermann
PubMed DOI Crossref
The relationship between circulating and tissue biomarkers and OA-related pain: A systematic literature review.
Mathieu S, Kuhi L, Binvignat M, ..., Sellam J, GO-PAIN working group
Osteoarthr Cartil Open 7 (4) 100684 [2025-12-00; online 2025-09-17]
PubMed DOI Crossref
The late stages of yeast mitoribosome large subunit biogenesis.
Rathore S, Conrad J, De Silva D, ..., Ott M, Barrientos A
Biochim Biophys Acta Mol Cell Res 1872 (8) 120051 [2025-12-00; online 2025-08-25]
PubMed DOI Crossref
The implementation of internet-delivered cognitive behaviour therapy for adolescents with insomnia comorbid to psychiatric conditions at two child and adolescent psychiatry clinics.
Lundén C, Khalifa N, Ramklint M, ..., Jernelöv S, Zetterqvist V
Psychiatry Res 354 (-) 116815 [2025-12-00; online 2025-10-28]
PubMed DOI Crossref
The effects of insulin-regulated aminopeptidase inhibition with HA08 on recognition memory acquisition and spatial working memory under reversed circadian conditions in male rats.
Stam F, Bjurling S, Zelleroth S, ..., Hallberg M, Grönbladh A
IBRO Neurosci Rep 19 (-) 854-861 [2025-12-00; online 2025-11-02]
PubMed DOI Crossref
That's So Last Season: Unraveling the Genomic Consequences of Fur Farming in Arctic Foxes (Vulpes lagopus).
Cockerill CA, Chacón-Duque JC, Bergfeldt N, ..., Dalén L, Norén K
Mol. Ecol. 34 (24) e70166 [2025-12-00; online 2025-11-13]
PubMed DOI Crossref
Targeting murine metastatic cancers with cholera toxin A1-adjuvanted peptide vaccines.
Paul S, Kaya M, Johnsson O, ..., Hellstrand K, Martner A
Hum Vaccin Immunother 21 (1) 2455240 [2025-12-00; online 2025-01-23]
PubMed DOI Crossref
TTSS-2 virulence drives inflammatory destruction of the gut epithelial barrier and modulates inflammatory response profiles in the Salmonella-infected mouse gut.
Enz U, Gül E, Maurer L, ..., Fattinger SA, Hardt WD
PLoS Pathog 21 (12) e1013733 [2025-12-00; online 2025-12-10]
PubMed DOI Crossref
Spatially resolved microRNA expression in tissues: technologies, challenges, and opportunities.
Robles-Remacho A, Zou Y, Grillo M, Nilsson M
Trends in Genetics 41 (12) 1131-1143 [2025-12-00; online 2025-07-11]
PubMed DOI Crossref
Spatial mapping of DNA synthesis reveals dynamics and geometry of human replication nanostructures.
Hawgood M, Urién B, Agostinho A, ..., Blom H, Lemmens B
EMBO J. 44 (23) 7263-7294 [2025-12-00; online 2025-10-07]
DOI Crossref
Spatial Transcriptomics Analysis of Histopathological Growth Patterns in Colorectal Liver Metastases Using In Situ Sequencing
Nyström H, Andersson A, Esciva Conde M, Nilsson M, Vermeulen P
European Journal of Surgical Oncology 51 (-) 110918 [2025-12-00; online 2025-12-00]
PubMed DOI Crossref
Selisistat, a SIRT1 inhibitor, enhances paclitaxel activity in luminal and triple-negative breast cancer: in silico, in vitro, and in vivo studies.
Wawruszak A, Luszczki J, Bartuzi D, ..., Czerwonka A, Stepulak A
J Enzyme Inhib Med Chem 40 (1) 2458554 [2025-12-00; online 2025-02-12]
PubMed DOI Crossref
Reprogramming Stars #25: Modeling Brain Aging with Direct Reprogramming of Skin Cells into Neurons-An Interview with Dr. Jerome Mertens.
Mertens J, Lopes M, Pereira CF
Cell Reprogram 27 (6) 207-212 [2025-12-00; online 2025-11-17]
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Reference proteins to improve performance of core 1 and core 2 Alzheimer's disease CSF and plasma biomarkers
Karlsson L, Janelidze S, Barthélemy NR, ..., Mattsson‐Carlgren N, Hansson O
Alzheimers Dement 21 (S2) - [2025-12-00; online 2025-12-24]
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Majidian S, Hadziahmetovic A, Langschied F, ..., Ouangraoua A, Julca I
J. Mol. Evol. 93 (6) 702-719 [2025-12-00; online 2025-10-14]
DDLS Fellow Sina Majidian
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Cumplido‐Mayoral I, Hristovska I, Binette AP, ..., Mattsson‐Carlgren N, Hansson O
Alzheimers Dement 21 (S2) - [2025-12-00; online 2026-01-08]
PubMed DOI Crossref
Prognostic Value of the Circulating Tumor DNA Fraction in Metastatic Castration-resistant Prostate Cancer: Results from the ProBio Platform Trial.
Crippa A, Laere B, Discacciati A, ..., Eklund M, ProBio Investigators
Eur Urol Oncol 8 (6) 1486-1495 [2025-12-00; online 2025-04-21]
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Pro-inflammatory differentiation by GM-CSF reduces prostanoid release and phagocytic activity in murine bone marrow-derived macrophages.
Liu J, Idborg H, Korotkova M, Jakobsson PJ
Prostaglandins Other Lipid Mediat 181 (-) 107044 [2025-12-00; online 2025-11-19]
PubMed DOI Crossref
Primary Human Tissue Models for Metabolic Dysfunction-Associated Liver Disease - toward Streamlining Drug Discovery with Patient-Derived Assays.
Youhanna S, Taebnia N, Liang Y, ..., Michel M, Lauschke VM
Adv Biol (Weinh) 9 (12) e00337 [2025-12-00; online 2025-11-07]
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Positron emission tomography to assess drug occupancy at peripheral and central incretin receptors.
Khalil A, Velikyan I, Xiong M, ..., Wagner M, Eriksson O
EBioMedicine 122 (-) 106033 [2025-12-00; online 2025-11-21]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Pangenomes as a framework for adaptive radiation, speciation, and adaptation.
Tellini N, Tørresen OK, Edwards D, ..., Jakobsen KS, Cerca J
American journal of botany 112 (12) e70130 [2025-12-00; online 2025-12-04]
DDLS Fellow José Cerca
PubMed DOI Crossref
PRIAMOS: A technique for mixing embedding media for freely adjusting pH value and refractive index (RI) for optical clearing (OC) of whole tissue samples.
Leischner U, Reifarth M, Brill MS, ..., Schubert US, Heintzmann R
J Microsc 300 (3) 302-314 [2025-12-00; online 2025-08-08]
PubMed DOI Crossref
OGG1 activation improves T cell resilience to oxidative stress after allo-SCT and T cell engager exposure.
Saul D, Lischer C, Bruns H, ..., Michel M, Mougiakakos D
Leukemia 39 (12) 3037-3041 [2025-12-00; online 2025-10-15]
DOI Crossref
Molecular classification of microsatellite-instable colorectal cancers reveals distinct predictors of immunotherapy response
Lin C, Luo T, Wu M, ..., Wu K, Sjöblom T
ESMO Gastrointestinal Oncology 10 (-) 100268 [2025-12-00; online 2025-12-00]
PubMed DOI Crossref
Misclassification of TP53 germline variants: implications for survival analysis in AML transplant studies.
Rodriguez L, Delhommeau F, Soussi T
Leukemia 39 (12) 3054-3055 [2025-12-00; online 2025-09-28]
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Metagenomic insights into the diet and past Kolyma Lowland habitat from the intestinal content of a Late Pleistocene steppe bison
Jin C, Forsythe A, Bálint M, ..., Guschanski K, van der Valk T
Quaternary Science Reviews 369 (-) 109604 [2025-12-00; online 2025-12-00]
PubMed DOI Crossref
Low Rate of Germline Investigation for Variants of Suspected Germline Origin Detected During the Diagnostic Work-Up of Myeloid Neoplasms.
Al-Djaber A, Munters A, Cammenga J, ..., Olsen TK, Baliakas P
EJHaem 6 (6) e70206 [2025-12-00; online 2025-12-16]
DOI Crossref
Individual functional connectivity constraints on spatial progression of tau pathology in Alzheimer's disease
Behjat HH, Vogel JW, Strandberg O, ..., Hansson O, Ossenkoppele R
Alzheimers Dement 21 (S2) - [2025-12-00; online 2026-01-08]
PubMed DOI Crossref
Improving accuracy in genome-wide association studies: a two-step approach for handling below limit of detection biomarker measurements.
Deng YA, Karlsson T, Johansson Å
NAR Genomics and Bioinformatics 7 (4) lqaf201 [2025-12-00; online 2025-12-31]
PubMed DOI Crossref
IgE-activated human lung mast cells preferentially release prostaglandin D2, thromboxane A2, and cysteinyl-leukotrienes.
Johnsson AK, Kolmert J, Rönnberg E, ..., Dahlén SE, Nilsson GP
J. Allergy Clin. Immunol. 156 (6) 1669-1678 [2025-12-00; online 2025-08-11]
DOI Crossref
How IT-specialized majors pay off: Evidence from an IT industry shock
Liu T
Labour Economics 97 (-) 102785 [2025-12-00; online 2025-12-00]
DOI Crossref
Hemispheric Asymmetry of Amyloid Deposition Influences Asymmetric Tau Pathology in Alzheimer’s Disease
Anijärv TE, Smith R, Collij LE, ..., Spotorno N, Hansson O
Alzheimers Dement 21 (S8) - [2025-12-00; online 2025-12-23]
DOI Crossref
Hemispheric Asymmetry of Amyloid Deposition Influences Asymmetric Tau Pathology in Alzheimer's Disease
Anijärv TE, Smith R, Collij LE, ..., Spotorno N, Hansson O
Alzheimers Dement 21 (S2) - [2025-12-00; online 2025-12-25]
PubMed DOI Crossref
Genome Variation in Three Anthophora Bee Species Reflects Divergent Demographic Histories.
Taliadoros D, Soares AER, Dias G, ..., Lindblad-Toh K, Webster MT
Mol. Ecol. 34 (24) e70204 [2025-12-00; online 2025-12-12]
PubMed DOI Crossref
Genetic composition and evolutionary trajectories of brain metastasis in non-small-cell lung cancer.
Nicoś M, Galant N, Kowalczyk A, ..., Jassem J, Crosetto N
Lung Cancer 210 (-) 108842 [2025-12-00; online 2025-11-14]
PubMed DOI Crossref
From slices to deep dishes: spatial transcriptomics and translatomics of thick tissue blocks.
Pleška M, Vickovic S
Nat. Methods 22 (12) 2500-2502 [2025-12-00; online 2025-11-25]
Sanja Vickovic SciLifeLab Fellow
PubMed DOI Crossref
From Nuclear Transplantation to Cellular Reprogramming-A Scientist Who Transformed Our View of Cell Identity.
Pereira F
Cell Reprogram 27 (6) 205-206 [2025-12-00; online 2025-11-18]
DOI Crossref
Estimating national Red List statuses for fungi in Sweden - An improved deep learning approach to account for unbalanced data
de Almeida FG, Baggström A, Andermann T
Ecological Informatics 92 (-) 103476 [2025-12-00; online 2025-12-00]
DDLS Fellow Tobias Andermann
DOI Crossref
EE710 The Hidden Clinical and Economic Costs of PPI Treatment Failures in Severe Erosive Esophagitis
Svangren P, Miller P
Value in Health 28 (12) S250 [2025-12-00; online 2025-12-00]
PubMed DOI Crossref
Dual roles of exostosin glycosyltransferase 1 in Zika virus infection.
Ling J, Khan A, Denkewitz M, ..., Li JP, Li J
Virulence 16 (1) 2458681 [2025-12-00; online 2025-02-10]
PubMed DOI Crossref
Diversity and evolution of alphaproteobacterial dimorphism.
Hallgren J, Jonas K
Curr Opin Microbiol 88 (-) 102661 [2025-12-00; online 2025-09-09]
Kristina Jonas SciLifeLab Fellow
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Disease timeline modelling of amyloid and tau PET reveals dynamic timescales of amyloid and tau accumulation in Alzheimer's disease
Young AL, Wijeratne PA, Aksman LM, ..., Vogel JW, Hansson O
Alzheimers Dement 21 (S2) - [2025-12-00; online 2026-01-07]
DOI Crossref
Derivatization of Small Molecules using Deuterated Analog of Reactive Matrix to Facilitate Identification in Mass Spectrometry Imaging
Vallianatou T, Balestri LJI, Nilsson A, ..., Andrén PE, Shariatgorji R
Chemistry Methods 5 (12) - [2025-12-00; online 2025-09-12]
DOI Crossref
Coordinated multi‐cellular responses to Alzheimer's disease pathology reveal sex‐specific resilience signatures
Vilkaite G, An L, Xiao Y, ..., Mattsson‐Carlgren N, Vogel JW
Alzheimers Dement 21 (S1) - [2025-12-00; online 2025-12-24]
PubMed DOI Crossref
Clinical and transcriptomic characterization of patients with chronic lymphocytic leukemia harboring t(14;19): an ERIC study.
Visentin A, Gaffo E, Fürstenau M, ..., Trentin L, Bortoluzzi S
Leukemia 39 (12) 2957-2967 [2025-12-00; online 2025-09-19]
PubMed DOI Crossref
Clinical Validation of Novel Immunoassays for Plasma Phosphorylated Tau 217, 212, 181, 231, and Brain-Derived Tau Across the Biochemical Spectrum of Alzheimer's Disease.
Dulewicz M, Kac PR, Ortiz FG, ..., Blennow K, Lewczuk P
J. Neurochem. 169 (12) e70313 [2025-12-00; online 2025-12-01]
PubMed DOI Crossref
Calcium stabilizes the flexible N-terminal domain of the bacterial ion channel DeCLIC.
Fan C, Lycksell M, Zhuang Y, Howard RJ, Lindahl E
J Struct Biol X 12 (-) 100139 [2025-12-00; online 2025-11-12]
DOI Crossref
CSF and plasma proteomic insights into the pathophysiology of cerebral small vessel disease and cerebrovascular event risk prediction
Hristovska I, Binette AP, Kumar A, ..., Vogel JW, Hansson O
Alzheimers Dement 21 (S2) - [2025-12-00; online 2025-12-24]
DOI Crossref
Brain connectivity drives tau presence while regional vulnerability drives tau load in Alzheimer's disease
Xiao Y, Spotorno N, An L, ..., Hansson O, Vogel JW
Alzheimers Dement 21 (S2) - [2025-12-00; online 2025-12-25]
DOI Crossref
Biological staging of Alzheimer's disease with the novel plasma eMTBR‐tau243 and %p‐tau217
Salvadó G, Horie K, Barthélemy NR, ..., Ossenkoppele R, Hansson O
Alzheimers Dement 21 (S2) - [2025-12-00; online 2025-12-24]
PubMed DOI Crossref
Biodiversity Genomics Research Practices Require Harmonising to Meet Stakeholder Needs in Conservation.
Buzan E, de Guttry C, Bortoluzzi C, ..., Mazzoni CJ, Waterhouse RM
Mol. Ecol. 34 (23) e70001 [2025-12-00; online 2025-06-26]
DOI Crossref
Benchmarking the AI‐based diagnostic potential of plasma proteomics for neurodegenerative disease in 17,710 people
An L, Xiao Y, Hristovska I, ..., Hansson O, Vogel JW
Alzheimers Dement 21 (S2) - [2025-12-00; online 2025-12-24]
PubMed DOI Crossref
Autosomal dominant primary hyperparathyroidism in the Keeshond dog breed is strongly associated with a missense variant in sirtuin-6.
Wade CM, Burmeister LM, Skelly BJ, ..., Lindblad-Toh K, Mellersh CS
Anim. Genet. 56 (6) e70056 [2025-12-00; online 2025-10-24]
PubMed DOI Crossref
Antigenic peptide delivery to antigen-presenting cells using a CD40-coiled coil affinity-based platform.
Nyesiga B, Hägerbrand K, Varas L, ..., Ellmark P, von Schantz L
Drug Deliv 32 (1) 2486340 [2025-12-00; online 2025-05-26]
DOI Crossref
APOE ε4 ‐related proteomic profiles in plasma and CSF
Lu L, Binette AP, Janelidze S, ..., Hansson O, Mattsson‐Carlgren N
Alzheimers Dement 21 (S2) - [2025-12-00; online 2025-12-26]
DOI Crossref
AI Superresolution: Converting T1‐weighted MRI from 3T to 7T resolution toward enhanced imaging biomarkers for Alzheimer’s disease
Gicquel M, Flood G, Zhao R, ..., Hansson O, Vogel JW
Alzheimers Dement 21 (S8) - [2025-12-00; online 2025-12-23]
DOI Crossref
AI Superresolution: Converting T1‐weighted MRI from 3T to 7T resolution toward enhanced imaging biomarkers for Alzheimer's disease
Gicquel M, Flood G, Zhao R, ..., Hansson O, Vogel JW
Alzheimers Dement 21 (S2) - [2025-12-00; online 2026-01-08]
DOI Crossref
A conditional two‐step approach for detecting Lewy Body pathology: smell function testing and α‐synuclein seed amplification
Mastenbroek SE, Collij LE, Vogel JW, ..., Ossenkoppele R, Hansson O
Alzheimers Dement 21 (S2) - [2025-12-00; online 2025-12-26]
DOI Crossref
Bayesian three-point water models
Nordman AT, Engblom S, van der Spoel D
npj Comput Mater 11 (1) - [2025-11-30; online 2025-11-30]
DOI Crossref
The histone methyltransferase SDG26 shapes cold stress responses in Arabidopsis through chromatin-based regulation of ABA-dependent and ABA-independent pathways
Zhang X, Zumsteg J, Erhardt M, Shen WH, Berr A
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DOI Crossref
Tangerine: a new family of Starships from lichen-forming fungi
Tagirdzhanova G, Brown NE, Bucknell AH, ..., Gluck-Thaler E, Talbot NJ
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SciLifeLab Fellow
PubMed DOI Crossref
Living on the edge: Temperature and salinity performance curves across levels of biological organization in a shallow water shrimp.
Missionário M, Bertalan R, Calado R, ..., Vinagre C, Madeira D
Mar Environ Res 214 (-) 107749 [2025-11-27; online 2025-11-27]
PubMed DOI Crossref
Human plasma proteomic profile of clonal hematopoiesis.
Yu Z, Vromman A, Nguyen NQH, ..., Gupta RM, Natarajan P
Nat Commun 16 (1) 11688 [2025-11-27; online 2025-11-27]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
Dynamic assembly of a large multidomain ribozyme visualized by cryo-electron microscopy.
Jadhav S, Maiorca M, Manigrasso J, ..., Topf M, Marcia M
Nat Commun 16 (1) 10195 [2025-11-27; online 2025-11-27]
PubMed DOI Crossref
Deleterious variants in the autophagy-related gene RB1CC1/FIP200 impair immunity to SARS-CoV-2.
Hu L, van der Sluis RM, Castelino KB, ..., Paludan SR, Mogensen TH
Nat Commun 16 (1) 10618 [2025-11-27; online 2025-11-27]
DOI Crossref
Structural basis for ATP regulation of human 5-lipoxygenase
Teder T, Pozzani F, Schulte T, ..., Orellana L, Haeggström JZ
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DOI Crossref
OncoRisk: A state-of-the-art Web Server for bridging the oncogenic databases and pan-cancer cohorts to the translational oncology
Mardinoglu A, Song X, Green E, ..., Uhlén M, Zhang C
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Adil Mardinoglu SciLifeLab Fellow
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Intrinsic heterogeneity of primary cilia revealed through spatial proteomics.
Hansen JN, Sun H, Kahnert K, ..., Axelsson U, Lundberg E
Cell 188 (24) 6804-6824.e16 [2025-11-26; online 2025-09-26]
PubMed DOI Crossref
Extending the shelf life of ⁶⁸Ge/⁶⁸Ga generators via preconcentration of [⁶⁸Ga]GaCl₃ for preclinical application.
Mallapura H, Eriksson O
EJNMMI Radiopharm Chem 10 (1) 76 [2025-11-26; online 2025-11-26]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Evidence for a functional interaction between yeast Pol ε and PCNA in vivo.
Singh N, Odai R, Persson U, ..., Atkinson GC, Johansson E
Nucleic Acids Res. 53 (22) - [2025-11-26; online 2025-12-17]
PubMed DOI Crossref
Chromogranin A and catestatin regulate pancreatic islet homeostasis, endocrine function, and neurotransmitter signaling.
Muntjewerff EM, Epremidze D, Nezhyva M, ..., Mahata SK, Christoffersson G
Commun Biol 8 (1) 1684 [2025-11-26; online 2025-11-26]
Daniel Espes Gustaf Christoffersson SciLifeLab Fellow
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The AML cellular state space unveils NPM1 immune evasion subtypes with distinct clinical outcomes.
Lilljebjörn H, Peña-Martínez P, Thorsson H, ..., Orsmark-Pietras C, Fioretos T
Nat Commun 16 (1) 10592 [2025-11-25; online 2025-11-25]
PubMed DOI Crossref
Seal milk oligosaccharides rival human milk complexity and exhibit functional dynamics during lactation.
Jin C, Lundstrøm J, Cori CR, ..., Khoo KH, Bojar D
Nat Commun 16 (1) 10067 [2025-11-25; online 2025-11-25]
DDLS Fellow
DOI Crossref
Nonlinear transcriptional responses to gradual modulation of transcription factor dosage
Domingo J, Minaeva M, Morris JA, ..., Sanjana NE, Lappalainen T
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DOI Crossref
The Swedish Reference Genome Portal: A Hub for Non-Human Eukaryotic Genomic Data Visualisation, Discovery, and Reuse
Lantz H, Brink D, Crean R, ..., Rung J, Fuentes-Pardo A
BISS 9 (-) - [2025-11-24; online 2025-11-24]
PubMed DOI Crossref
Proteomics discovery of MTDH and SND1 interaction vulnerabilities in ovarian cancer.
Esmaeili P, Nasimian A, Werner L, ..., Kazi JU, Levander F
Sci Rep 15 (1) 41818 [2025-11-24; online 2025-11-24]
PubMed DOI Crossref
Blood biomarkers of Alzheimer's disease and progression across different stages of cognitive decline in the community.
Valletta M, Vetrano DL, Gregorio C, ..., Fratiglioni L, Grande G
Nat Commun 16 (1) 10412 [2025-11-23; online 2025-11-23]
PubMed DOI Crossref
Paleogenomic evidence on the temporal continuity of indigenous goat exploitation in the Canary Islands.
Díaz-Pérez C, Santana J, Daly KG, ..., Arnay M, Fregel R
iScience 28 (11) 113771 [2025-11-21; online 2025-10-13]
PubMed DOI Crossref
Multi-cellular phenotypic dynamics during the progression of an immunocompetent breast cancer model.
Gsell L, Watson SS, Sutevski I, ..., Joyce JA, Hausser J
iScience 28 (11) 113808 [2025-11-21; online 2025-10-23]
Jean Hausser SciLifeLab Fellow
PubMed DOI Crossref
Depression is an independent risk factor for stroke reccurence and cognitive impairment in stroke patients.
Cankaya S, Safa SS, Karakus A, ..., Kumral E, Yulug B
Transl Psychiatry 15 (1) 492 [2025-11-21; online 2025-11-21]
Adil Mardinoglu SciLifeLab Fellow
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Spatially heterogeneous inhibition projects sequential activity onto unique neural subspaces
Lehr AB, Kumar A, Tetzlaff C
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DOI Crossref
Spatially heterogeneous inhibition projects sequential activity onto unique neural subspaces
Lehr AB, Kumar A, Tetzlaff C
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PubMed DOI Crossref
Single cell long read whole genome sequencing reveals somatic transposon activity in human brain.
Izydorczyk MB, Kalef-Ezra E, Horner DW, ..., Sedlazeck FJ, Proukakis C
Commun Biol 8 (1) 1627 [2025-11-20; online 2025-11-20]
DOI Crossref
NUDT5 regulates the global efficacy of nucleoside analog drugs by coordinating purine synthesis and PRPP allocation
Valerie NCK, Alam S, Hormann FM, ..., Arvidsson PI, Altun M
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PubMed DOI Crossref
Genomic and biogeographic patterns of endemic geckos in the Galapagos Islands reveal population structure and species delimitation on inhabited islands.
Pozo G, Guadalupe JJ, Pozo MJ, ..., Velasco-Cedeño D, Torres ML
Sci Rep 15 (1) 41016 [2025-11-20; online 2025-11-20]
DDLS Fellow José Cerca
PubMed DOI Crossref
Characterization of the bone marrow architecture of multiple myeloma using spatial transcriptomics.
Muiños-Lopez E, Lopez-Perez AR, Sudupe L, ..., Gomez-Cabrero D, Prosper F
Commun Biol 8 (1) 1620 [2025-11-20; online 2025-11-20]
PubMed DOI Crossref
Myxococcus xanthus for active matter studies: a tutorial for its growth and potential applications.
Antúnez Domínguez JM, Pérez García L, Rivera-Yoshida N, ..., Adiels CB, Volpe G
Soft Matter 21 (45) 8602-8623 [2025-11-19; online 2025-11-19]
PubMed DOI Crossref
Local, calcium- and reward-based synaptic learning rule that enhances dendritic nonlinearities can solve the nonlinear feature binding problem.
Khodadadi Z, Trpevski D, Lindroos R, Hellgren Kotaleski J
Elife 13 (-) - [2025-11-17; online 2025-11-17]
DOI Crossref
Local, calcium- and reward-based synaptic learning rule that enhances dendritic nonlinearities can solve the nonlinear feature binding problem
Khodadadi Z, Trpevski D, Lindroos R, Hellgren Kotaleski J
Elife 13 (-) - [2025-11-17; online 2025-11-17]
PubMed DOI Crossref
Maternal exposure to trace elements and perfluoroalkyl acids and their associations with alterations of the hypothalamic-pituitary-adrenal axis.
Soomro MH, England-Mason G, Giesbrecht GF, ..., Martin JW, Dewey D
Environ. Res. 285 (Pt 2) 122379 [2025-11-15; online 2025-07-16]
PubMed DOI Crossref
Differences in the faecal microbiome of obese and non-obese pregnant women: a matched cohort study in Sweden.
Patavoukas E, Tong B, Guðnadóttir U, ..., Wiberg-Itzel E, Hugerth L
BMC Microbiol. 25 (1) 750 [2025-11-15; online 2025-11-15]
DDLS Fellow Luisa Hugerth
PubMed DOI Crossref
Progress and future outlook towards a safe and sustainable production and use of chemicals.
Munthe J, Bergström L, Bolinius D, ..., Witala M, Syrén PO
Commun Chem 8 (1) 350 [2025-11-14; online 2025-11-14]
PubMed DOI Crossref
Identification of protein biomarkers to differentiate between gram-negative and gram-positive infections in adults suspected of sepsis
Irani Shemirani M, Pernestig AK, Björkman J, ..., Ejdebäck M, Ståhlberg A
BMC Infect Dis 25 (1) 1576 [2025-11-14; online 2025-11-14]
Astrid von Mentzer DDLS Fellow
PubMed DOI Crossref
Noscapine-bile acid hybrids as novel anticancer agents.
Babanezhad Harikandei K, Salehi P, Hasanpour Z, ..., Asghari SM, Mardinoglu A
RSC Med Chem 16 (11) 5511-5533 [2025-11-13; online 2025-08-29]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Improving GRPR-targeting peptides for radiotheranostics application: insights from chelator modifications and α-methyl-L tryptophan substitution.
Obeid K, Bezverkhniaia E, Tolmachev V, Orlova A, Kanellopoulos P
EJNMMI Radiopharm Chem 10 (1) 74 [2025-11-13; online 2025-11-13]
PubMed DOI Crossref
Giving an Enzyme Scissors: Serotonin Derivatives as Potent Organocatalytic Switches for DNA Repair Enzyme OGG1.
Varga M, Ortis F, Del Prado A, ..., Watson AJB, Michel M
J Med Chem 68 (21) 22455-22483 [2025-11-13; online 2025-10-15]
PubMed DOI Crossref
Ancient host-associated microbes obtained from mammoth remains.
Guinet B, Oskolkov N, Moreland K, ..., Dalén L, van der Valk T
Cell 188 (23) 6606-6619.e24 [2025-11-13; online 2025-09-02]
DDLS Fellow Tom van der Valk
PubMed DOI Crossref
Molecular insights into nucleocapsid assembly and transport in Marburg and Ebola viruses.
Takamatsu Y, Dolnik O, Hirabayashi A, ..., Oda Harumi C, Noda T
MBio 16 (11) e0155725 [2025-11-12; online 2025-09-22]
PubMed DOI Crossref
CD46 is a cellular receptor for species D human adenovirus.
Danskog K, Petersen F, Frängsmyr L, ..., Lenman A, Arnberg N
MBio 16 (11) e0158725 [2025-11-12; online 2025-09-22]
DOI Crossref
A streamlined nanopore-compatible 5PSeq protocol for rapid phenotypic antimicrobial sensitivity testing
Liu H, Huch S, Hull R, ..., Du J, Pelechano V
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SciLifeLab Fellow
PubMed DOI Crossref
Underestimated input of terrestrial dissolved organic carbon to the ocean.
Yi Y, Tanentzap AJ, He C, ..., Zhao M, He D
Proc. Natl. Acad. Sci. U.S.A. 122 (45) e2505838122 [2025-11-11; online 2025-11-03]
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Persistence-Directed Testing of Chemicals Discharged from Offshore Oil Platforms Combined with Nontargeted Analysis.
Møller MT, Birch H, Sjøholm KK, ..., Martin JW, Mayer P
Environ. Sci. Technol. 59 (44) 24000-24011 [2025-11-11; online 2025-10-29]
PubMed DOI Crossref
Correction to: Investigating recurrence in pilonidal sinus disease: results of a nationwide, multicenter study in Turkey (PISI TURKEY).
Yalcinkaya A, Yalcinkaya A, Sahin C, ..., Leventoglu S, PISI TURKEY Study Collaboration
Int J Colorectal Dis 40 (1) 229 [2025-11-11; online 2025-11-11]
PubMed DOI Crossref
Anti-Tumoral Treatment with Thioredoxin Reductase 1 Inhibitor Auranofin Fosters Regulatory T Cell and B16F10 Expansion in Mice.
Bonner MY, Vancsik T, Oliveira-Coelho A, ..., Arnér ESJ, Holmdahl R
Antioxidants (Basel) 14 (11) - [2025-11-11; online 2025-11-11]
PubMed DOI Crossref
Targeting the parietal memory network with tDCS in MCI: study protocol for a randomized controlled trial.
Cankaya S, Akturk A, Karakus A, ..., Mardinoglu A, Yulug B
Front. Hum. Neurosci. 19 (-) 1661790 [2025-11-10; online 2025-11-10]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Optimization of a synoviocyte-targeted biologic for inflammatory arthritis in combination or bispecific administration with TNF inhibitors.
Ramsey SH, Zhao Z, Lee MC, ..., Stanford SM, Bottini N
JCI Insight 10 (21) - [2025-11-10; online 2025-09-30]
DOI Crossref
ALC1 Finds a New Foothold on the Nucleosome’s Super-Groove
Bridges HR, Bacic L, Deindl S, Gaullier G
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Molecular profiling of ex vivo prostate cancer CAF models captures stromal heterogeneity and drug vulnerabilities.
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Does human cytomegalovirus provide a novel therapeutic target for patients with glioblastoma?
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Spatial single-cell atlas reveals regional variations in healthy and diseased human lung.
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Longitudinal development of sex differences in the limbic system is associated with age, puberty and mental health.
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Commun Biol 8 (1) 1524 [2025-11-05; online 2025-11-05]
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Unraveling the conformational landscape of amyloid precursor protein intracellular domain.
Mandal N, Skepö M
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Keeping Wnt in check for efficient checkpoint blockade in glioblastoma.
Melssen M, Dimberg A
Proc. Natl. Acad. Sci. U.S.A. 122 (44) e2523639122 [2025-11-04; online 2025-10-27]
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FibrilPaint to determine the length of Tau amyloids in fluids.
Aragonès Pedrola J, Dekker FA, Garfagnini T, ..., Friedler A, Rüdiger SGD
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Denitrifier activity drives diurnal N 2 O flux dynamics in a thawing arctic permafrost
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Comparative evaluation of Olink Explore 3072 and mass spectrometry with peptide fractionation for plasma proteomics.
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Commun Chem 8 (1) 327 [2025-11-04; online 2025-11-04]
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T2T-CHM13 improves read mapping and detection of clinically relevant genetic variation in the Swedish population.
Schmitz D, Ameur A, Johansson Å
Genome Res 35 (11) 2377-2388 [2025-11-03; online 2025-11-03]
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Single-cell multi-omics uncovers differentiation-dependent transcriptional programs shaping epigenetic subgroups in AML
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Blood 146 (Supplement 1) 5005-5005 [2025-11-03; online 2025-11-03]
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Enhanced spatial clustering of single-molecule localizations with graph neural networks.
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Nat Commun 16 (1) 9693 [2025-11-03; online 2025-11-03]
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Blind prediction of complex water and ion ensembles around RNA in CASP16.
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Adaptive introgression from Pacific herring to Atlantic herring in the brackish Baltic Sea
Ferreira MS, Felkel S, Fuentes-Pardo AP, ..., Pettersson M, Andersson L
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Mafalda Sousa Ferreira SciLifeLab Fellow
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Neuroimmune interactions in the pancreas in health and disease- Identifying the components of nerve-macrophage association 2911
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J. Immunol. 214 (Supplement_1) - [2025-11-01; online 2025-11-20]
Gustaf Christoffersson SciLifeLab Fellow
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Longitudinal gut microbial trajectories show differences in early life LPS exposure and IFNγ responses 4153
Arzoomand A, Lou TE, Sahi M, ..., Schwenk J, Brodin P
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IntegrAlign: a comprehensive tool for multi-immunofluorescence panel integration through image alignment.
Hermet L, Laoubi L, Scavino M, ..., Caux C, Hubert M
Bioinformatics 41 (11) - [2025-11-01; online 2025-10-16]
Jean Hausser SciLifeLab Fellow
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Clonal Hematopoiesis and Risk of New-Onset Myocarditis and Pericarditis.
Schuermans A, Flynn S, Niroula A, ..., Natarajan P, Honigberg MC
JAMA Cardiol 10 (11) 1147-1156 [2025-11-01; online 2025-09-01]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
pHyph, a novel antibiotic-free treatment for bacterial vaginosis, promotes Lactobacillus growth and reduces the abundance of pathogens in the vagina.
Lahtinen E, Hugerth LW, Edfeldt G, ..., Strevens H, Schuppe-Koistinen I
AJOG Glob Rep 5 (4) 100566 [2025-11-00; online 2025-09-14]
DDLS Fellow Luisa Hugerth
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White Matter Regional Volumes in Relation to Menstrual Cycle Phase and Premenstrual Dysphoric Disorder.
Stenhammar E, Dubol M, Stiernman L, ..., Bixo M, Comasco E
Biol Psychiatry Glob Open Sci 5 (6) 100573 [2025-11-00; online 2025-07-28]
Erika Comasco SciLifeLab Fellow
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The pcnB gene sustains Shigella flexneri virulence.
Frisch T, Geiser P, Komi M, ..., Sellin ME, Di Martino ML
PLoS Pathog 21 (11) e1013727 [2025-11-00; online 2025-11-20]
Mikael Sellin SciLifeLab Fellow
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The circulating dihydrotestosterone/testosterone ratio is increased by gut microbial 5α-reductase activity in females.
Ohlsson C, Li L, Horkeby K, ..., Fall T, Grahnemo L
EBioMedicine 121 (-) 105978 [2025-11-00; online 2025-10-21]
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Spatiotemporal gene expression and cellular dynamics of the developing human heart.
Lázár E, Mauron R, Andrusivová Ž, ..., Adameyko I, Lundeberg J
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Skalierbares Darmorganoidmodell enthüllt humanpathogene Infektionsfaktoren
Jenniches L, Di Martino ML, Sellin ME, Barquist L
Biospektrum 31 (7) 712-714 [2025-11-00; online 2025-11-22]
Mikael Sellin SciLifeLab Fellow
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SF3B1-mutant models of RNA mis-splicing uncover UBA1 as a therapeutic target in myelodysplastic neoplasms.
Thier J, Hofmann S, Kirchhof KM, ..., Moura PL, Lundin V
Leukemia 39 (11) 2801-2811 [2025-11-00; online 2025-08-26]
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SAG1.3-derived Frizzled-targeting small-molecule compounds.
Grätz L, Turku A, Kozielewicz P, ..., Gmeiner P, Schulte G
J Biol Chem 301 (11) 110751 [2025-11-00; online 2025-09-22]
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Reticulate and Hybrid Speciation is Promoted by Environmental Instability in an Indo-Pacific Species Complex of Whistlers (Aves: Pachycephala).
Irestedt M, Müller IA, Thörn F, ..., van der Valk T, Jønsson KA
Mol. Ecol. 34 (21) e70018 [2025-11-00; online 2025-07-12]
DDLS Fellow Tom van der Valk
PubMed DOI Crossref
Report on the 2nd MObility for Vesicle research in Europe (MOVE) symposium-2024.
Rodrigues-Junior DM, Kocholata M, Lekka ME, ..., Yadid M, Kosanovic M
FEBS Open Bio 15 (11) 1726-1737 [2025-11-00; online 2025-08-29]
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Proximity extension assay inflammatory profiling cannot distinguish the presence of residual C-peptide in patients with long-standing type 1 diabetes.
Anvari E, Lundkvist P, Singh K, Espes D
Acta diabetologica 62 (11) 1987-1996 [2025-11-00; online 2025-06-05]
Daniel Espes SciLifeLab Fellow
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Prenatal exposure to endocrine disrupting chemicals and the association with behavioural difficulties in 7-year-old children in the SELMA study.
Stratmann M, Özel F, Marinopoulou M, ..., Gennings C, Bornehag CG
J Expo Sci Environ Epidemiol 35 (6) 981-991 [2025-11-00; online 2024-12-19]
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Perspective of Brazilian biochemistry and molecular biology professors about ethical training
Rodrigues-Junior DM
International Journal of Ethics Education 10 (2) 389-397 [2025-11-00; online 2025-08-06]
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Modulation of OGG1 enzymatic activity by the cellular machinery - have all the boxes been ticked?
Eddershaw A, Rudolfová N, Dawson H, Benítez-Buelga C, Michel M
DNA Repair (Amst.) 155 (-) 103904 [2025-11-00; online 2025-10-15]
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MALNC: a new mutant NPM1/IDH2R140 and PML-RARA-associated lncRNA with impact on AML cell proliferation, maturation and drug response.
Cozzi E, Neddermeyer A, Zhong X, ..., Lennartsson A, Lehmann S
Cancer Gene Ther. 32 (11) 1191-1205 [2025-11-00; online 2025-08-23]
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Inflammatory Mediators Related to Vascular Dysfunction are Linked to ICP, PRx, and CPP Following Human Severe Traumatic Brain Injury.
Smith CA, Lindblad C, Needham E, ..., Thelin E, Helmy A
J. Neurotrauma 42 (21-22) 1974-1984 [2025-11-00; online 2025-08-04]
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Impact of socio-economic and patient-centered characteristics on access to Alzheimer's disease medication in primary care: A population-based study in the Stockholm county, Sweden.
Shaker A, Ljunggren G, Vossen LE, Religa D, Raaschou P
J. Alzheimers Dis. 108 (1) 180-192 [2025-11-00; online 2025-09-16]
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Heparan sulfate N-deacetylase/N-sulfotransferase-1 regulates glioblastoma cell migration and invasion.
Spyrou A, Roy A, Xiong A, ..., Kjellén L, Forsberg-Nilsson K
Matrix Biol. 141 (-) 1-15 [2025-11-00; online 2025-08-10]
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HAPP: High-accuracy pipeline for processing deep metabarcoding data.
Sundh J, Granqvist E, Iwaszkiewicz-Eggebrecht E, ..., Andersson AF, Ronquist F
PLoS Comput Biol 21 (11) e1013558 [2025-11-00; online 2025-11-07]
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Genomic analysis of a Neisseria meningitidis patient isolate causing a false-positive result in the Abbott Alinity m STI, Sweden: a case report.
Herrmann B, Sälléber A, Kaden R
ASM Case Rep 1 (6) - [2025-11-00; online 2025-09-30]
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Genetic mapping in the red mason bee implicates ANTSR as an ancient sex-determining locus in bees and ants.
Rönneburg T, Taliadoros D, Olsson A, ..., Seidelmann K, Webster MT
PLoS Biol. 23 (11) e3003458 [2025-11-00; online 2025-11-03]
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Epigenetic alterations facilitate transcriptional and translational programs in hypoxia.
Watt K, Dauber B, Szkop KJ, ..., Larsson O, Postovit LM
Nat. Cell Biol. 27 (11) 1965-1981 [2025-11-00; online 2025-10-16]
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Ephemeral Speciation in a New Guinean Honeyeater Complex (Aves: Melidectes).
Müller IA, Thörn F, Rajan S, ..., Irestedt M, Jønsson KA
Mol. Ecol. 34 (21) e17760 [2025-11-00; online 2025-04-11]
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Differences in the Fecal Metabolome of Autoimmune Pancreatitis Patients
Nikolić S, Dovhalyuk V, Yang F, ..., Löhr JM, Globisch D
Pancreatology 25 (7) 1325 [2025-11-00; online 2025-11-00]
Daniel Globisch SciLifeLab Fellow
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Decoding the ankle-brachial index in peripheral artery disease: coronary versus valvular calcification.
Petri MH, Haftbaradaran Esfahani P, Plunde O, Bäck M
Eur Heart J Open 5 (6) oeaf134 [2025-11-00; online 2025-10-22]
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Continuous Glucose Monitoring Data Analysis 2.0: Functional Data Pattern Recognition and Artificial Intelligence Applications.
Klonoff DC, Bergenstal RM, Cengiz E, ..., Ho CN, Healey E
J Diabetes Sci Technol 19 (6) 1515-1527 [2025-11-00; online 2025-08-14]
Daniel Espes SciLifeLab Fellow
PubMed DOI Crossref
Cardiovascular Morbidity in Patients Undergoing Successful Surgery for Primary Hyperparathyroidism.
Nilsson M, Smith JG, Thier M, ..., Bergenfelz A, Almquist M
Clin. Endocrinol. (Oxf) 103 (5) 669-681 [2025-11-00; online 2025-08-12]
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Aquatic fungal diversity assessment through metagenomics is still limited to current databases
Sanyal A, Kluge M, Redondo MA, ..., Bertilsson S, Peura S
Limnol. Oceanogr. 70 (11) 3249-3260 [2025-11-00; online 2025-09-12]
Sarahi Garcia Sari Peura SciLifeLab Fellow
PubMed DOI Crossref
An anti-CEA affibody showing high-definition staining in human pancreatic cancer tissue sections and selective tumor targeting in vivo.
Nilvebrant J, Moro CF, Papalanis E, ..., Björnstedt M, Nygren PÅ
Transl Oncol 61 (-) 102512 [2025-11-00; online 2025-08-28]
PubMed DOI Crossref
Allosteric control of the bacterial ClpC/ClpP protease and its hijacking by antibacterial peptides.
Jenne T, Engelhardt L, Baronaite I, ..., Carroni M, Mogk A
EMBO J. 44 (21) 6273-6296 [2025-11-00; online 2025-09-29]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Abnormalities in the functional activity of neural networks in a human iPSC model of Dravet syndrome.
Mzezewa R, Hyvärinen T, Kulta O, ..., Dahl N, Narkilahti S
Neurosci Res 220 (-) 104958 [2025-11-00; online 2025-09-19]
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5P Artificial intelligence-driven spatial proteomics analysis identifies prognostic markers of mucinous differentiation in rectal cancer
Fan C, Zhao K, Vernmark K, ..., Stadler C, Sun XF
ESMO Real World Data and Digital Oncology 10 (-) 100204 [2025-11-00; online 2025-11-00]
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466 Cancer intrinsic protein neddylation reprograms macrophage metabolism to constrain immune checkpoint blockade therapy
Papakyriacou I, Lu Y, Bedos MR, ..., Puigvert JC, Mao Y
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SciLifeLab Fellow Yumeng Mao
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Spatial transcriptomics reveals an unexpected impact of tau and tau pathology on the expression of transthyretin.
Croteau DL, Navarro JF, Comptdaer T, ..., Lundeberg J, Galas MC
Front Aging Neurosci 17 (-) 1656850 [2025-10-31; online 2025-10-31]
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Large-scale causal discovery using interventional data sheds light on gene network structure in k562 cells.
Brown BC, Tokolyi A, Morris JA, Lappalainen T, Knowles DA
Nat Commun 16 (1) 9628 [2025-10-31; online 2025-10-31]
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Hidden network preserved in Slide-tags data allows reference-free spatial reconstruction.
Dahlberg SK, Bonet DF, Franzén L, Ståhl PL, Hoffecker IT
Nat Commun 16 (1) 9652 [2025-10-31; online 2025-10-31]
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Exploring penetrance of clinically relevant variants in over 800,000 humans from the Genome Aggregation Database.
Gudmundsson S, Singer-Berk M, Stenton SL, ..., MacArthur DG, O'Donnell-Luria A
Nat Commun 16 (1) 9623 [2025-10-31; online 2025-10-31]
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Comparative analysis of whole genome amplification kits for single-cell genome analysis
Hernández-Hernández A, Höjer P, Ljungmark M, ..., Nordlund J, Mezger A
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Modeling cryo-EM structures in alternative states with AlphaFold2-based models and density-guided simulations.
Shugaeva T, Howard RJ, Haloi N, Lindahl E
Commun Chem 8 (1) 317 [2025-10-30; online 2025-10-30]
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Cryo-specimen preparation and imaging of highly-structured and dynamic large non-coding RNAs
Jadhav S, Marcia M
BMC Methods 2 (1) - [2025-10-30; online 2025-10-30]
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Comparative analysis of the uptake of the H+/OC antiporter substrate oxycodone across and into brain endothelial and parenchymal cells with in vitro-in vivo extrapolation.
Bällgren F, Svane N, Ginosyan A, ..., Brodin B, Loryan I
Fluids Barriers CNS 22 (1) 109 [2025-10-30; online 2025-10-30]
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An evo-devo resource for wood: Comparative regulomics across dicot and conifer trees
Hvidsten T, Rodriguez E, Birkeland S, ..., Mellerowicz E, Street N
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Evolution of Large Polymorphic Inversions in a Panmictic Songbird.
Pei Y, Forstmeier W, Suh A, ..., Wolf J, Kempenaers B
Mol. Biol. Evol. 42 (11) - [2025-10-29; online 2025-10-17]
PubMed DOI Crossref
Accumulation of a Biparentally Inherited Neptune Transposable Element in Natural Killifish Hybrids (Fundulus diaphanus × F. heteroclitus).
Roussel AJ, Suh A, Ruiz-Ruano FJ, Dion-Côté AM
Mol. Biol. Evol. 42 (11) - [2025-10-29; online 2025-10-16]
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A dual genetic constraint underlies the conservation of early brains in vertebrates
Senovilla-Ganzo R, Bekiari C, Rueda-Alaña E, ..., Kaessmann H, García-Moreno F
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PubMed DOI Crossref
A Novel Supergene Controls Queen Size and Colony Social Organization in the Ant Myrmica ruginodis.
Sigeman H, Seppä P, Downing PA, ..., Helanterä H, Viljakainen L
Mol. Biol. Evol. 42 (11) - [2025-10-29; online 2025-10-13]
PubMed DOI Crossref
Pooled overexpression screening identifies PIPPI as a novel microprotein involved in the ER stress response.
Lafranchi L, Raja GL, Arenas AM, ..., Branca RMM, Elsӓsser SJ
Nucleic Acids Res. 53 (20) - [2025-10-28; online 2025-11-09]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
A denaturation-free protocol for in situ visualization of short nuclear DNA sequences using padlock probes with rolling-circle amplification.
Ikebuchi R, Xi L, Bouri D, ..., Dumanski JP, Landegren U
PLoS ONE 20 (10) e0335619 [2025-10-28; online 2025-10-28]
PubMed DOI Crossref
Time-resolved Mendelian randomization detects substantial variation in the detrimental effect of obesity throughout life.
Karlsson T, Hadizadeh F, Rask-Andersen M, Schmitz D, Johansson Å
Sci Adv 11 (43) eadv0926 [2025-10-24; online 2025-10-24]
PubMed DOI Crossref
Comparing methods collecting mucosal secretions and detecting SARS-CoV-2 spike IgA in three laboratories across three countries.
Bladh O, Aguilera K, Sheikh-Mohamed S, ..., Thålin C, Simon V
Vaccine 65 (-) 127792 [2025-10-24; online 2025-10-04]
PubMed DOI Crossref
Targeted proteomics identifies differentially expressed proteins in Sjögren's disease with incident lymphoma.
Imgenberg-Kreuz J, Fugmann C, Molin AM, ..., Nordmark G, Steering committee
RMD Open 11 (4) - [2025-10-23; online 2025-10-23]
PubMed DOI Crossref
Patient-specific sequencing panels enable sensitive circulating tumor DNA analysis in rhabdomyosarcoma independent of genetic profile.
Rahmqvist I, Dahlstrand Rudin A, Mellström E, ..., Ståhlberg A, Dalin M
NPJ Precis Oncol 9 (1) 327 [2025-10-21; online 2025-10-21]
DOI Crossref
Lymphatics unload VEGFR3 in response to the alteration of VEGFR2-mediated transcriptional programs
Li T, Cao X, Zhou F, ..., Claesson-Welsh L, He Y
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ELASTO-INERTIAL SPIRAL MICROFLUIDICS FOR SIZE-BASED PARTICLE SEPARATION APPLIED IN SEPSIS DIAGNOSTICS
Chávez-Ramos K, Tanriverdi S, Zaremba D, ..., Jönsson H, Russom A
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PubMed DOI Crossref
Ultrafast, remote-controlled protonation reaction enables structural changes in a phytochrome.
Shankar MK, Grunewald L, Wahlgren WY, ..., Ihalainen JA, Westenhoff S
Sci Adv 11 (42) eady0499 [2025-10-17; online 2025-10-17]
PubMed DOI Crossref
Structure-guided allosteric modulation of the delta opioid receptor.
Mobbs JI, Nguyen MD, Deo O, ..., Valant C, Thal DM
bioRxiv - (-) - [2025-10-17; online 2025-10-17]
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Prodan-based solvatochromic probes for polarity imaging of organelles
Aknine N, Holban P, Ragaller F, ..., Sezgin E, Klymchenko AS
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Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Statistical Superiority Without Clinical Relevance: A Critical Appraisal of Recent Hyaluronic Acid Filler Studies.
Hicks J, Bromée T, Andriopoulos B
Aesthet Surg J 45 (11) NP208-NP209 [2025-10-16; online 2025-07-25]
PubMed DOI Crossref
Distribution of photosensitive fagopyrin in buckwheat flowers and its potential biological relevance.
Hornyák M, Kula-Maximenko M, Miszalski Z, ..., Göransson U, Slazak B
Sci Rep 15 (1) 36279 [2025-10-16; online 2025-10-16]
PubMed DOI Crossref
Association of estrogen receptor single nucleotide polymorphisms and perinatal depression.
Björvang RD, Gumbo LF, Årdahl A, ..., Fransson E, Skalkidou A
PLoS ONE 20 (10) e0334705 [2025-10-16; online 2025-10-16]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Adverse Cardiometabolic Outcomes in Men With Sisters With Polycystic Ovary Syndrome.
Kanina A, Stener-Victorin E, Butwicka A, ..., Rosenqvist MA, Cesta CE
J. Clin. Endocrinol. Metab. 110 (11) e3810-e3817 [2025-10-16; online 2025-03-04]
PubMed DOI Crossref
A mosaic of modular variation at a single gene underpins convergent plumage coloration.
Lutgen D, Peona V, Chase MA, ..., Schielzeth H, Burri R
Science (New York, N.Y.) 390 (6770) eado8005 [2025-10-16; online 2025-10-16]
PubMed DOI Crossref
A generative deep learning approach to de novo antibiotic design.
Krishnan A, Anahtar MN, Valeri JA, ..., Wong F, Collins JJ
Cell 188 (21) 5962-5979.e22 [2025-10-16; online 2025-08-14]
Andreas Luttens DDLS Fellow
DOI Crossref
“Universal Hyb-Seq kits capture considerable intraspecific variation: Less is more in herbarium-inclusive molecular ecology”
Woudstra Y, Quatela AS, Wagemaker NC, ..., Gravendeel B, Verhoeven KJ
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SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
The potential role of environmentally associated DNA methylation in childhood acute lymphoblastic leukaemia subtypes.
Saville JR, Russell LJ, Padget K, ..., Nordlund J, McKay JA
Int. J. Cancer 157 (8) 1600-1612 [2025-10-15; online 2025-06-09]
PubMed DOI Crossref
Retinal tau phosphorylation in Alzheimer's disease: A mass spectrometry study.
Santiago J, Pocevičiūtė D, Vogel J, ..., Brinkmalm G, Wennström M
Neurobiol. Dis. 215 (-) 107057 [2025-10-15; online 2025-08-18]
PubMed DOI Crossref
Reference genome bias in light of species-specific chromosomal reorganization and translocations.
Maurstad MF, Hoff SNK, Cerca J, ..., Præbel K, Jentoft S
Genome Biol. 26 (1) 355 [2025-10-15; online 2025-10-15]
DDLS Fellow José Cerca
PubMed DOI Crossref
PAT-on-a-chip: Miniaturization of analytical assays towards data-driven bioprocess development and optimization.
Pinto IF, Abeille F, Giehring S, ..., Chotteau V, Russom A
Biosens Bioelectron 286 (-) 117625 [2025-10-15; online 2025-05-23]
PubMed DOI Crossref
Novel macrocyclic peptidomimetics targeting the insulin-regulated aminopeptidase (IRAP): design, synthesis and evaluation.
Olaniran Håkansson E, Balestri LJI, Puthiyaparambath S, ..., Skillinghaug B, Odell LR
RSC Med Chem 16 (10) 5059-5069 [2025-10-15; online 2025-08-06]
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Force-Triggered Thermodynamically Uphill Disulfide Reduction through Sulfur Oxidation State Control.
Mora M, Cohen G, Cranton W, ..., Stirnemann G, Garcia-Manyes S
Journal of the American Chemical Society 147 (41) 37701-37707 [2025-10-15; online 2025-10-01]
PubMed DOI Crossref
Erratum to "Reply to letter to the editor for the "Relationship between iron deficiency and expression of genes involved in iron metabolism in human myocardium and skeletal muscle" " [International Journal of Cardiology Volume 385, 15 August 2023, Page 43].
Cabrera C, Frisk C, Löfström U
Int. J. Cardiol. 437 (-) 133473 [2025-10-15; online 2025-06-11]
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DDLS Fellow Kimmo Kartasalo
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Parajuli A, Bendes A, Byvald F, ..., Schwenk JM, Flodström-Tullberg M
Diabetologia 68 (10) 2277-2289 [2025-10-00; online 2025-08-04]
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Haars J, Wallin F, Elfving K, ..., Palanisamy N, Lennerstrand J
Infect Dis (Lond) 57 (10) 956-965 [2025-10-00; online 2025-05-26]
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Klycheva K, Gyger J, Frund M, ..., Cava F, Fumeaux C
PLoS Pathog 21 (10) e1013633 [2025-10-00; online 2025-10-21]
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Björvang RD, Vrettou M, Bujanda Cundin X, ..., Comasco E, Skalkidou A
Mol. Psychiatry 30 (10) 4736-4748 [2025-10-00; online 2025-06-05]
Erika Comasco SciLifeLab Fellow
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Dovhalyuk V, Yang F, Nikolic S, ..., Löhr JM, Globisch D
United European Gastroenterol J 13 (8) 1560-1570 [2025-10-00; online 2025-04-17]
Daniel Globisch SciLifeLab Fellow
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Phytochemistry Letters 69 (-) 103442 [2025-10-00; online 2025-10-00]
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Missima NG, Hill H, Aioanei CS, Liss P, Espes D
Endocrine 90 (1) 140-148 [2025-10-00; online 2025-07-12]
Daniel Espes SciLifeLab Fellow
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A standardized framework for circulating blood proteomics.
Cai X, Geyer PE, Perez-Riverol Y, ..., Völker U, Guo T
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A roadmap for equitable reuse of public microbiome data.
Hug LA, Hatzenpichler R, Moraru C, ..., Data Reuse Consortium , Probst AJ
Nat. Microbiol 10 (10) 2384-2395 [2025-10-00; online 2025-09-26]
DDLS Fellow Luisa Hugerth
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Structural uncertainty in mapping Euro-Atlantic atmospheric rivers obscures understanding of associated meteorological extremes.
Thandlam V, Rutgersson A, Sahlée E
Sci Rep 15 (1) 33325 [2025-09-29; online 2025-09-29]
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Sexual dimorphism in zebrafish liver proteins and implications for hepatic regeneration and diseases.
Niksirat H, Mengal K, Kor G, Steinbach C, Levander F
Sci Rep 15 (1) 33565 [2025-09-29; online 2025-09-29]
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Plasma proteomic and metabolomic profiling of coronary and carotid atherosclerosis in the SCAPIS study-differences and similarities.
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Cardiovasc Res 121 (11) 1649-1652 [2025-09-29; online 2025-05-06]
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Maternal aggression driven by the transient mobilisation of a dormant hormone-sensitive circuit.
Stagkourakis S, Williams P, Spigolon G, ..., Fisone G, Broberger C
Nat Commun 16 (1) 8553 [2025-09-29; online 2025-09-29]
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PKSmart: an open-source computational model to predict intravenous pharmacokinetics of small molecules.
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J Cheminform 17 (1) 147 [2025-09-26; online 2025-09-26]
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Liquid biomarkers associate with TGF-β Type I receptor and hypoxia in kidney cancer.
Mallikarjuna P, Erdem C, Beorlegui RI, ..., Kamali-Moghaddam M, Landström M
Signal Transduct Target Ther 10 (1) 309 [2025-09-26; online 2025-09-26]
Cemal Erdem DDLS Fellow
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Childhood brain tumours instruct cranial haematopoiesis and immunotolerance
Cooper E, Posner DA, Lee CYC, ..., Clatworthy MR, Gilbertson RJ
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An injury-associated lobular microniche is associated with the classical tumor cell phenotype in pancreatic cancer.
Söderqvist S, Viljamaa A, Geyer N, ..., Fernández Moro C, Gerling M
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The molecular infrastructure of glutamatergic synapses in the mammalian forebrain.
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Elife 13 (-) - [2025-09-25; online 2025-09-25]
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Targeting PKLR and lipogenic enzymes through JNK inhibition to develop a therapeutic strategy for MASLD and MASH
Mardinoglu A, Kim W, Li M, ..., Zhang C, Turkez H
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Adil Mardinoglu SciLifeLab Fellow
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Resilience of the Gut Microbiome to Short Proton Pump Inhibitor Therapy With or Without High-Dosage L. reuteri in H. pylori-Infected Adults.
Bibbò S, Ahlström G, Pes GM, ..., Merola E, Dore MP
Helicobacter 30 (5) e70064 [2025-09-25; online 2025-09-25]
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Idiopathic inflammatory myopathies lack neutralising autoantibodies to type- I, II and III interferons.
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RMD Open 11 (3) - [2025-09-25; online 2025-09-25]
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Author response: The molecular infrastructure of glutamatergic synapses in the mammalian forebrain
Peukes J, Lovatt C, Leistner C, ..., Grant SG, Frank RA
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Online reinforcement learning of state representation in recurrent network supported by the power of random feedback and biological constraints.
Tsurumi T, Kato A, Kumar A, Morita K
Elife 14 (-) - [2025-09-24; online 2025-09-24]
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Online reinforcement learning of state representation in recurrent network supported by the power of random feedback and biological constraints
Tsurumi T, Kato A, Kumar A, Morita K
Elife 14 (-) - [2025-09-24; online 2025-09-24]
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Retrospective Validation of an Artificial Intelligence System for Diagnostic Assessment of Prostate Biopsies on the ProMort Cohort: Study Protocol
Ji X, Zelic R, Aspegren O, ..., Akre O, Kartasalo K
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DDLS Fellow Kimmo Kartasalo
PubMed DOI Crossref
Long-read sequencing reveals the RNA isoform repertoire of neuropsychiatric risk genes in human brain.
De Paoli-Iseppi R, Joshi SS, Gleeson J, ..., Parker BL, Clark MB
Genome Biol. 26 (1) 298 [2025-09-23; online 2025-09-23]
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POMC-specific modulation of metabolic and immune pathways via melanocortin-3 receptor signaling.
Nezhyva M, Sandbaumhüter FA, Andrén PE, Jansson ET
Mol Omics 21 (5) 456-463 [2025-09-22; online 2025-09-22]
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Metagenomic analysis of viral diversity in Portuguese bats.
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Vet Res Commun 49 (6) 319 [2025-09-20; online 2025-09-20]
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Low-Dose Aspirin for PI3K-Altered Localized Colorectal Cancer.
Martling A, Hed Myrberg I, Nilbert M, ..., Lindberg J, ALASCCA Study Group
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LipiGo: A Versatile DNA-Lipid Nanoparticle Hybrid for Precision Drug Delivery
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Erdinc Sezgin SciLifeLab Fellow
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GRK-biased adrenergic agonists for the treatment of type 2 diabetes and obesity.
Motso A, Pelcman B, Kalinovich A, ..., Wright SC, Bengtsson T
Cell 188 (19) 5142-5156.e23 [2025-09-18; online 2025-06-23]
Jens Carlsson SciLifeLab Fellow
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Targeted ferroptosis induction enhances chemotherapy efficacy in chemoresistant neuroblastoma.
Mañas A, Seger A, Adamska A, ..., Aaltonen K, Bexell D
NPJ Precis Oncol 9 (1) 311 [2025-09-16; online 2025-09-16]
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Impact of early-life human microbiota on the murine host metabolome: insights from a two-generation HMA mouse model and implications for allergic disease.
de Jong YA, Seren RM, Ramšak Marčeta V, ..., Qazi KR, Sverremark-Ekström E
BMC Microbiol. 25 (1) 575 [2025-09-16; online 2025-09-16]
Sarahi Garcia SciLifeLab Fellow
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Gene copy number variation (gCNV) contributes to adaptation along environmental gradient
Zhou Q, Lascoux M, Milesi P
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Pascal Milesi SciLifeLab Fellow
PubMed DOI Crossref
Effects of Oligolysine-Polyethylene Glycol Coating on the Biodistribution of Wireframe DNA Origami Nanosheets in Zebrafish Embryos.
Kolonelou C, Engström E, Bräutigam L, ..., Andersson O, Teixeira AI
ACS Nano 19 (36) 32145-32157 [2025-09-16; online 2025-09-03]
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Gain-of-function enhancer variant near KCNB1 causes familial ST-depression syndrome.
Christensen AH, Pan G, Marvig RL, ..., Wadelius C, Bundgaard H
Eur. Heart J. 46 (35) 3486-3497 [2025-09-15; online 2025-04-10]
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Discovery of novel triphenylphosphonium conjugated pleuromutilin with enhanced anti-MRSA effect and broaden antibacterial spectrum.
Feng B, Hu H, Xiang J, ..., Li T, Wu S
Eur J Med Chem 294 (-) 117731 [2025-09-15; online 2025-05-11]
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4D flow MRI enhances prototype testing of a total artificial heart.
Bakker T, Najar A, Finocchiaro T, ..., Lantz J, Ebbers T
Sci Rep 15 (1) 32533 [2025-09-15; online 2025-09-15]
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Genetic background of neurological disorders with basal ganglia calcification.
Yektay Farahmand M, Wallenius J, Wasselius J, ..., Puschmann A, Ilinca A
J Neurol 272 (9) 632 [2025-09-14; online 2025-09-14]
PubMed DOI Crossref
Temporal control of human DNA replication licensing by CDK4/6-RB signalling and chemical genetics.
Sosenko Piscitello A, Nilsson AS, Hawgood M, ..., Halazonetis TD, Lemmens B
Nat Commun 16 (1) 8268 [2025-09-12; online 2025-09-12]
PubMed DOI Crossref
Lab-on-PCB with integrated DNA amplification and electroanalytical detection for point-of-care diagnostics.
Thorapalli Muralidharan S, Hanze M, Ainla A, ..., Hamedi MM, Toldrà A
Sci Rep 15 (1) 32418 [2025-09-12; online 2025-09-12]
DOI Crossref
Interdisciplinary Study on Drug-Induced-Phospholipidosis of Repurposing Libraries through Machine Learning and Experimental Evaluation in Different Cell Lines
Wendt J, Kuzikov M, Kalman A, ..., Gribbon P, Zaliani A
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DOI Crossref
Fundamental Limits of Inferring Dynamical Gene Regulatory Models from Single-Cell Data
Balubaid A, Bernal Tamyo JP, Kumar R, ..., Kiani N, Tegner J
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DOI Crossref
Benchmarking long-read RNA-sequencing technologies with LongBench: a cross-platform reference dataset profiling cancer cell lines with bulk and single-cell approaches
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Accurate Protein Dynamic Conformational Ensembles: Combining AlphaFold, MD, and Amide 15N(1H) NMR Relaxation.
Lesovoy D, Roshchin K, Sala BM, ..., Agback P, Orekhov V
Int J Mol Sci 26 (18) - [2025-09-12; online 2025-09-12]
PubMed DOI Crossref
Investigating recurrence in pilonidal sinus disease: results of a nationwide, multicenter study in Turkey (PISI TURKEY).
Yalcinkaya A, Yalcinkaya A, Sahin C, ..., Leventoglu S, PISI TURKEY Study Collaboration
Int J Colorectal Dis 40 (1) 194 [2025-09-11; online 2025-09-11]
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Genome sequences of six clinical isolates of Candida parapsilosis exhibiting different degrees and temporal regulation of biofilm formation.
Shafeeq S, Pannanusorn S, Dainat J, ..., Nystedt B, Römling U
Microbiol Resour Announc 14 (9) e0130024 [2025-09-11; online 2025-08-11]
PubMed DOI Crossref
Follow-up of incidentally detected mild to moderate ascending aortic dilation and risk factors for rapid progression in a Swedish middle-aged population.
Kylhammar D, Nilsson F, Dyverfeldt P, ..., Engvall J, Swahn E
Heart 111 (19) 904-909 [2025-09-11; online 2025-09-11]
DOI Crossref
Flexible and rapid validation of structural variation using adaptive sampling
Feuk L, Paivandy A, Lenner F, ..., Lindstrand A, Scherer S
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DOI Crossref
Epithelial dysfunction as a driver of symptoms in gastrointestinal disorders
Denadai-Souza A, Denadai-Souza A, Modave E, ..., Voet T, Boeckxstaens G
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Local, calcium- and reward-based synaptic learning rule that enhances dendritic nonlinearities can solve the nonlinear feature binding problem
Khodadadi Z, Trpevski D, Lindroos R, Hellgren Kotaleski J
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Narrow band imaging complements eosinophilic esophagitis reference score in predicting inflammatory infiltration in patients with dysphagia.
Truskaite K, Vossen Engblom L, Lindberg G, Dlugosz A
Endosc Int Open 13 (-) a26857610 [2025-09-09; online 2025-09-09]
PubMed DOI Crossref
Immunogenicity and innate immunity to high-dose and repeated vaccination of modified mRNA versus unmodified mRNA.
Engstrand O, Joas G, Miranda MC, ..., Reinhardt A, Loré K
Mol Ther Nucleic Acids 36 (3) 102588 [2025-09-09; online 2025-06-09]
PubMed DOI Crossref
Computational pathology annotation enhances the resolution and interpretation of breast cancer spatial transcriptomics data.
Li T, Yang Q, Acs B, ..., Chen X, Hartman J
NPJ Precis Oncol 9 (1) 310 [2025-09-09; online 2025-09-09]
Camilla Engblom SciLifeLab Fellow
PubMed DOI Crossref
Chemoenzymatic cascade depolymerization of plastics.
Sun S, Syrén PO
Commun Chem 8 (1) 272 [2025-09-09; online 2025-09-09]
DOI Crossref
Accurate characterization of CRISPR-Cas9 genome editing outcomes and mosaicism with near-perfect long reads
Höijer I, van Schendel R, Emmanouilidou A, ..., den Hoed M, Ameur A
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PubMed DOI Crossref
Virulence factors and outcomes in bacteremia caused by extended-spectrum β-lactamase-producing uropathogenic Escherichia coli ST131-H30Rx in a Swedish county.
Möller V, Welander J, Nilsson M, ..., Östholm Å, Berglund B
BMC Infect Dis 25 (1) 1103 [2025-09-08; online 2025-09-08]
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Rapid label-free identification of seven bacterial species using microfluidics, single-cell time-lapse phase-contrast microscopy, and deep learning-based image and video classification.
Hallström E, Kandavalli V, Wählby C, Hast A
PLoS ONE 20 (9) e0330265 [2025-09-08; online 2025-09-08]
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Polygenic scores in Familial breast cancer cases with and without pathogenic variants and the risk of contralateral breast cancer.
Kvist A, Kämpe A, Törngren T, ..., Borg Å, Eriksson D
Breast Cancer Res. 27 (1) 160 [2025-09-08; online 2025-09-08]
PubMed DOI Crossref
Thiazole-fused thiazoliniums with ketone warheads as covalent inhibitors targeting Cys44 of SARS-CoV-2 3CLpro.
Cao Q, Zhang Z, Zhu G, ..., Ge G, Li B
Chem. Biol. Interact. 418 (-) 111620 [2025-09-05; online 2025-06-24]
Ruisheng Xiong SciLifeLab Fellow
PubMed DOI Crossref
Hemispheric asymmetry of tau pathology is related to asymmetric amyloid deposition in Alzheimer's Disease.
Anijärv TE, Ossenkoppele R, Smith R, ..., Spotorno N, Hansson O
Nat Commun 16 (1) 8232 [2025-09-05; online 2025-09-05]
PubMed DOI Crossref
The Earth BioGenome Project Phase II: illuminating the eukaryotic tree of life.
Blaxter M, Lewin HA, DiPalma F, ..., Waterhouse RM, EBP Community of Scientists
Front Sci 3 (-) - [2025-09-04; online 2026-02-02]
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ProbeST: a custom probe design pipeline for Spatial Transcriptomics
Rouot S, van Dolderen I, Andreassen PR, ..., Vorholt JA, Giacomello S
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Pre- and Post-synaptic Mechanisms of Neuronal Inhibition Assessed Through Biochemically Detailed Modeling of GABAB Receptor Signaling.
Mäki-Marttunen T, Kismul JF, Pajo K, ..., Andreassen OA, Kotaleski JH
J. Neurosci. 45 (36) - [2025-09-03; online 2025-09-03]
PubMed DOI Crossref
Unravelling the Complexity of Sarcopenia Through a Systems Biology Approach.
Ceyhan AB, Altay O, Zhang C, ..., Turkez H, Mardinoglu A
Int J Mol Sci 26 (17) - [2025-09-02; online 2025-09-02]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
An In Vivo Fluorescence Image Analysis Tool for Esterase Activity Quantification in Daphnia: Using Calcein AM in Ecotoxicological Studies.
Perez-Liñan A, Abele C, Pierozan P, Breitholtz M, Karlsson O
Environ. Sci. Technol. 59 (34) 18023-18032 [2025-09-02; online 2025-08-21]
Oskar Karlsson SciLifeLab Fellow
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U-FISH: a fluorescent spot detector for imaging-based spatial-omics analysis and AI-assisted FISH diagnosis.
Xu W, Cai H, Zhang Q, ..., Ouyang W, Cao G
Genome Biol. 26 (1) 261 [2025-09-01; online 2025-09-01]
DDLS Fellow Wei Ouyang
PubMed DOI Crossref
Subjective cognitive decline in major depressive patients is associated with altered entropy and connectivity changes of temporal and insular region.
Yulug B, Yalcinkaya A, Safa SS, ..., Hanoglu L, Mardinoglu A
Transl Psychiatry 15 (1) 335 [2025-09-01; online 2025-09-01]
Adil Mardinoglu SciLifeLab Fellow
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Peer Review Report For: From Recruitment to Retirement: Research Infrastructure Staff Views on the Diversification of Scientific Career Paths at Universities in Sweden in 2024 [version 1; peer review: 1 approved, 3 approved with reservations]
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PKP1 promotes lung cancer by modulating energy metabolism through stabilization of PFKP.
Ritoré-Salazar F, Arenas AM, Matia-González AM, ..., Noguera NI, Medina PP
Biomark Res 13 (1) 112 [2025-09-01; online 2025-09-01]
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Immune-coagulation dynamics in severe COVID-19 revealed by autoantibody profiling and multi-omics integration.
Ambikan AT, Cederholm A, Rezene S, ..., Landegren N, Gupta S
Sci Rep 15 (1) 32149 [2025-09-01; online 2025-09-01]
PubMed DOI Crossref
Understanding the transport of drugs across biomimetic barriers of various phospholipid compositions using a combined experimental and computational approach.
Kabedev A, Tønning MH, Teleki A, Bauer-Brandl A, Jacobsen AC
Colloids Surf B Biointerfaces 253 (-) 114706 [2025-09-00; online 2025-04-21]
Alexandra Teleki SciLifeLab Fellow
PubMed DOI Crossref
The association between antenatal SARS-CoV-2 exposure and infant neurodevelopment at four months of age: A prospective multicenter cohort survey within the COPE study.
Berg J, Linden K, Zaigham M, ..., Sengpiel V, Andersson O
Int J Infect Dis 158 (-) 107973 [2025-09-00; online 2025-07-03]
PubMed DOI Crossref
Tertiary lymphoid structures in Merkel cell carcinoma facilitate naïve and central memory T-cell infiltration linked to immunotherapy response
Srinivas N, Spassova I, Lei KC, ..., Lui WO, Becker JC
J Immunother Cancer 13 (9) e012224 [2025-09-00; online 2025-09-23]
Camilla Engblom SciLifeLab Fellow
PubMed DOI Crossref
Systematic profiling of cancer-fibroblast interactions reveals drug combinations in ovarian cancer.
Gudoityte G, Sharma O, Leuenberger L, ..., Kallioniemi O, Seashore-Ludlow B
Mol Oncol 19 (9) 2574-2593 [2025-09-00; online 2025-05-24]
DOI Crossref
Synthesis of Two Neutrophil Elastase Inhibitors by Palladium-mediated [11C]cyanations
Wilson V, Zhang H, Estrada S, ..., Eriksson O, Antoni G
Nuclear medicine and biology 148-149 (-) 109076 [2025-09-00; online 2025-09-00]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Streptomyces uses both polar and dispersed cell wall synthesis during exploratory growth.
Zambri MP, Baglio CR, Irazoki O, ..., Cava F, Elliot MA
Nat. Microbiol 10 (9) 2245-2256 [2025-09-00; online 2025-08-08]
PubMed DOI Crossref
Small Bugs, Big Data: Metagenomics for Arthropod Biodiversity Monitoring.
López Clinton S, Iwaszkiewicz-Eggebrecht E, Miraldo A, ..., Ronquist F, van der Valk T
Ecol Evol 15 (9) e72163 [2025-09-00; online 2025-09-16]
DDLS Fellow Tom van der Valk
PubMed DOI Crossref
SKI regulates rRNA transcription and pericentromeric heterochromatin to ensure centromere integrity and genome stability.
Pola-Véliz V, Carrero D, Sagredo EA, ..., Armisén R, Marcelain K
Neoplasia 67 (-) 101204 [2025-09-00; online 2025-07-02]
PubMed DOI Crossref
Reply to J Drouin-Chartier and J Lessard-Lord.
Zhang S, Smith JG, Borné Y, Sonestedt E
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Protein-ligand data at scale to support machine learning.
Edwards AM, Owen DR, Structural Genomics Consortium Target 2035 Working Group
Nat Rev Chem 9 (9) 634-645 [2025-09-00; online 2025-07-23]
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POSTER: AML-570 Predictive Value of Microbiome and Metabolomic Biomarkers in Myeloid Neoplasms
Campagna A, Clasen F, Garcia-Guevara F, ..., Porta MGD, Shoaie S
Clinical Lymphoma Myeloma and Leukemia 25 (-) S190 [2025-09-00; online 2025-09-00]
Saeed Shoaie SciLifeLab Fellow
DOI Crossref
P32-07 Can we unravel cocktail effects in skin sensitization? A proteomics-centred approach
de Ávila RI, Carreira-Santos S, Siino V, ..., Levander F, Zeller KS
Toxicol. Lett. 411 (-) S426 [2025-09-00; online 2025-09-00]
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Oral contraceptive use increases bone density and reduces the risk of osteoporosis.
Ivansson EL, Johansson T, Karlsson T, Johansson Å
Eur. J. Epidemiol. 40 (9) 1123-1131 [2025-09-00; online 2025-07-09]
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Multilayered Epigenetic Analysis Identifies a Molecular Portrait for Psychological Resilience in Patients With Breast Cancer.
Richter C, Dethlefsen O, Axelsson U, ..., Hallberg IR, Borrebaeck CAK
Biol Psychiatry Glob Open Sci 5 (5) 100545 [2025-09-00; online 2025-06-03]
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Mechanical control of breast cancer malignancy by promotion of mevalonate pathway enzyme synthesis.
Göransson S, Olofsson H, Johansson HJ, ..., Lehtiö J, Strömblad S
Matrix Biol. 140 (-) 1-15 [2025-09-00; online 2025-06-12]
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Longitudinal big biological data in the AI era.
Mardinoglu A, Turkez H, Shong M, ..., Hood L, Uhlen M
Mol Syst Biol 21 (9) 1147-1165 [2025-09-00; online 2025-08-05]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Interaction between haploinsufficiency of PTPN2 and patient microbiome promotes autoimmune arthritis in mice.
Sendo S, Vela AJ, Ro M, ..., Stanford SM, Bottini N
J. Autoimmun. 156 (-) 103452 [2025-09-00; online 2025-08-01]
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Increased risk of skin cancer in mastocytosis: A large-scale retrospective cohort study of over 20,000 patients.
Bergström A, Lambe M, Nilsson G, ..., Ludwig RJ, Curman P
J Am Acad Dermatol 93 (3) 835-837 [2025-09-00; online 2025-05-19]
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In-depth patient-specific analysis of tumor heterogeneity in melanoma brain metastasis: Insights from spatial transcriptomics and multi-region bulk sequencing.
Sharma N, Rájová J, Mermelekas G, ..., Pernemalm M, Eriksson H
Transl Oncol 59 (-) 102468 [2025-09-00; online 2025-07-15]
PubMed DOI Crossref
Illuminating druggable dark matter in RNA virus replication using in situ cryo-EM.
Sharma H, Sorin MN, Sharma KB, Carlson LA
Curr Opin Virol 72 (-) 101475 [2025-09-00; online 2025-07-09]
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Genomic studies in Linum shed light on the evolution of the distyly supergene and the molecular basis of convergent floral evolution.
Zervakis PI, Postel Z, Losvik A, ..., Churcher A, Slotte T
New Phytol. 247 (6) 2964-2981 [2025-09-00; online 2025-07-18]
SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Genomic profiling of enterotoxigenic Escherichia coli toxins and adhesins in livestock isolates from Kenya.
Njoroge SM, Kulohoma BW, Falzon LC, ..., von Mentzer A, Fèvre EM
Microb Genom 11 (9) - [2025-09-00; online 2025-09-25]
Astrid von Mentzer DDLS Fellow
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Genomic determinants of therapy response in ETV6::RUNX1 leukemia.
Oksa L, Moisio S, Maqbool K, ..., Lohi O, Heinäniemi M
Leukemia 39 (9) 2125-2139 [2025-09-00; online 2025-07-09]
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Genomic and morphological analysis reveals long-term mammoth hybridization in British Columbia, Canada.
Dehasque M, van der Valk T, Chacón-Duque JC, ..., Lister A, Dalén L
Biol. Lett. 21 (9) 20250305 [2025-09-00; online 2025-09-24]
DDLS Fellow Tom van der Valk
PubMed DOI Crossref
Gene and pathway analysis of genome-wide genetic associations of bladder cancer.
Shi M, Meng X, Xu X, Wang Q
Curr Urol 19 (5) 321-330 [2025-09-00; online 2025-06-05]
DDLS Fellow Qiaoli Wang
PubMed DOI Crossref
Fluctuating DNA methylation tracks cancer evolution at clinical scale.
Gabbutt C, Duran-Ferrer M, Grant HE, ..., Martin-Subero JI, Graham TA
Nature 645 (8081) 764-773 [2025-09-00; online 2025-09-10]
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Distinct Phenotypes of Peripheral Innate Lymphoid Cells and T Cells in Type 2 and Non-Type 2 Asthma.
Kere MM, Björkander S, Merid SK, ..., Tibbitt CA, Melén E
Clin Transl Allergy 15 (9) e70108 [2025-09-00; online 2025-09-18]
PubMed DOI Crossref
Disease-specific U1 spliceosomal RNA mutations in mature B-cell neoplasms.
Nadeu F, Shuai S, Clot G, ..., Puente XS, Campo E
Leukemia 39 (9) 2076-2086 [2025-09-00; online 2025-06-30]
PubMed DOI Crossref
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence.
Liblova Z, Maurencova D, Salovska B, ..., Vajrychova M, Hodny Z
Mol Oncol 19 (9) 2619-2647 [2025-09-00; online 2025-04-27]
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Contextualizing Telomere Biology Through Biopsychological Plasticity: Insights From the Differential Susceptibility Hypothesis.
Comasco E
Biol Psychiatry Glob Open Sci 5 (5) 100548 [2025-09-00; online 2025-06-07]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Competition and cooperation of assembly sequences in recurrent neural networks.
Stöber TM, Lehr AB, Nikzad A, ..., Fyhn M, Kumar A
PLoS Comput Biol 21 (9) e1013403 [2025-09-00; online 2025-09-12]
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Comorbid posttraumatic stress disorder complicates eating disorder treatment: A nationwide study.
Hübel C, Johansson T, Mundy J, ..., Isomaa R, Birgegård A
Psychiatry Res 351 (-) 116563 [2025-09-00; online 2025-05-24]
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Building immunoglobulin and T cell receptor gene databases for the future
Watson CT, Collins AM, Ohlin M, ..., Lees WD, Yaari G
ImmunoInformatics 19 (-) 100059 [2025-09-00; online 2025-09-00]
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Bispecific brain-penetrant antibodies for treatment of Alzheimer's disease.
Sehlin D, Hultqvist G, Michno W, ..., Lopes van den Broek S, Syvänen S
J Prev Alzheimers Dis 12 (8) 100214 [2025-09-00; online 2025-05-26]
SciLifeLab Fellow Wojciech Michno
PubMed DOI Crossref
Biased signaling via serotonin 5-HT2A receptor: From structural aspects to in vitro and in vivo pharmacology.
Jastrzębski MK, Wójcik P, Grudzińska A, ..., Targowska-Duda KM, Kaczor AA
Acta Pharm Sin B 15 (9) 4438-4455 [2025-09-00; online 2025-07-05]
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Author Correction: Estrogen receptor activation remodels TEAD1 gene expression to alleviate hepatic steatosis.
Sommerauer C, Gallardo-Dodd CJ, Savva C, ..., Williams C, Kutter C
Mol Syst Biol 21 (9) 1282-1283 [2025-09-00; online 2025-06-12]
Claudia Kutter Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Author Correction: A universal language for finding mass spectrometry data patterns.
Damiani T, Jarmusch AK, Aron AT, ..., Dorrestein PC, Wang M
Nat. Methods 22 (9) 1995 [2025-09-00; online 2025-08-09]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
Aurora 2.0: A fluorogenic dye library for expanding the capability of protein-adaptive differential scanning fluorimetry (paDSF).
Charvat AF, Mason-Chalmers K, Grabinska-Rogala A, ..., Vinueza NR, Gestwicki JE
SLAS Discov 35 (-) 100259 [2025-09-00; online 2025-08-08]
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A novel PML germline variant as a candidate predisposing genetic aberration in familial acute myeloid leukaemia.
Soussi T, Kundu S, Gerbaud P, ..., Sjöblom T, Baliakas P
Br. J. Haematol. 207 (3) 1118-1121 [2025-09-00; online 2025-07-07]
DOI Crossref
A Diastereoselective Mizoroki–Heck Reaction for Synthesis of Spirooxindole-Based Nonnatural Amino Acids Using a Boc-Protected Amine Chiral Auxiliary
Larhed M, Lindman J, Puthiyaparambath S, Gising J, Odell LR
Synlett 36 (14) 2009-2013 [2025-09-00; online 2025-04-29]
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A Base-Mediated Rearrangement of the Benzylic 1,5-Hexadipyridynyl Moiety.
Remmerswaal WA, Nguyen TT, Han Z, ..., Zhu W, Erdelyi M
Chempluschem 90 (9) e202500252 [2025-09-00; online 2025-08-04]
Ruisheng Xiong SciLifeLab Fellow
DOI Crossref
Interferon-α–Driven Stratification of B Cell Reveals Metabolic Reprogramming of Double Negative, Naive and Transitional cell subsets and Refines Molecular Classification in Sjögren’s Disease
Iperi C, Rekha AA, Arvidsson G, ..., Jamin C, Bordron A
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Hybrid Sequencing Characterization of Complex Chromosomal Rearrangements.
Lindstrand A, Eisfeldt J
Methods in molecular biology (Clifton, N.J.) 2968 (-) 151-159 [2025-08-30; online 2025-08-30]
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On being (not so) different: perceptions of gender dysphoria and neurodiversity among people aged 15-35 in Sweden.
Özel F, Griffin G
Front Sociol 10 (-) 1610206 [2025-08-29; online 2025-08-29]
PubMed DOI Crossref
Colchicine and Longitudinal Dynamics of Clonal Hematopoiesis: An Exploratory Substudy of the LoDoCo2 Trial.
Mohammadnia N, Xue L, Vestjens LTW, ..., El Messaoudi S, Honigberg MC
J. Am. Coll. Cardiol. - (-) - [2025-08-29; online 2025-08-29]
Abhishek Niroula DDLS Fellow
DOI Crossref
A novel mechanism for bacterial sporulation based on programmed peptidoglycan degradation
Ramírez Carbó CA, Irazoki O, Venkatesan S, ..., Cava F, Nan B
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PubMed DOI Crossref
Spatial TCR clonality and clonal expansion in the in situ microenvironment of non-small cell lung cancer.
Yu H, Magoulopoulou A, Amini RM, ..., Strell C, Micke P
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Germline genetic variation impacts clonal hematopoiesis landscape and progression to malignancy.
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Detection of antibodies against the African parasite Trypanosoma brucei using synthetic glycosylphosphatidylinositol oligosaccharide fragments.
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A stratified treatment algorithm in psychiatry: a program on stratified pharmacogenomics in severe mental illness (Psych-STRATA): concept, objectives and methodologies of a multidisciplinary project funded by Horizon Europe.
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Ex Vivo Drug Sensitivity of Pleural Effusion-Derived Cells from Lung Cancer and Pleural Mesothelioma Patients Is Linked to Clinical Response.
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Validation of Guidelines for Genetic Investigation of Myeloid Neoplasms with Germline Predisposition: Results from a Prospective Cohort Study.
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Lord E, Feinauer IS, Soares AER, ..., Dalén L, Díez-Del-Molino D
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Crawford CJ, Tomlinson CWE, Gunawan C, ..., Williams SJ, Cartmell A
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Cancer Cell 43 (7) 1328-1346.e8 [2025-07-14; online 2025-05-29]
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Eur. Heart J. 46 (27) 2691-2701 [2025-07-14; online 2025-04-28]
Clemens Wittenbecher DDLS Fellow
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BMC Genomics 26 (1) 665 [2025-07-14; online 2025-07-14]
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Anticancer effects and mechanisms of Pulsatilla chinensis, Bupleurum chinense and Polyporus umbellatus on human lung carcinoma and hepatoma cells.
Li M, Kim W, Jin H, ..., Zhang C, Mardinoglu A
Comput Struct Biotechnol J 27 (-) 3066-3078 [2025-07-13; online 2025-07-13]
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PARP9-PARP13-PARP14 axis tunes colorectal cancer response to radiotherapy.
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Intestinal estrogen receptor beta modulates the murine colon tumor immune microenvironment.
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Claudia Kutter SciLifeLab Fellow
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MBio 16 (7) e0091125 [2025-07-09; online 2025-05-30]
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Serum Exosomal Multi-Omic Signatures Stratify Glucose Tolerance in Cystic Fibrosis and Reveal Partial Therapeutic Reprogramming by CFTR Modulators
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Sequence, structure, and affinity of miR-34a binding sites determine repression efficacy.
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DDLS Fellow Luisa Hugerth
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Plasma protein biomarkers of Plasmodium falciparum infection in pregnant women: a high-throughput proteomics study.
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Front. Cell. Infect. Microbiol. 15 (-) 1594088 [2025-07-08; online 2025-07-08]
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FeatureForest: the power of foundation models, the usability of random forests.
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Auditory-Perceptual Analysis of Speech Outcomes Following HiCommunication Intervention in Parkinson's Disease-A Secondary Analysis of a Randomized Controlled Trial.
Steurer H, Gustafsson JK, Franzén E, Schalling E
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Optimized Artificial Colonic Mucus Enabling Physiologically Relevant Diffusion Studies of Drugs, Particles, and Delivery Systems.
Tjakra M, Chakrapeesirisuk N, Jacobson M, ..., Teleki A, Bergström CAS
Mol. Pharm. 22 (7) 4032-4045 [2025-07-07; online 2025-06-10]
Alexandra Teleki Mikael Sellin SciLifeLab Fellow
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Factor XII-driven coagulation traps bacterial infections.
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Development and retrospective validation of an artificial intelligence system for diagnostic assessment of prostate biopsies: study protocol.
Mulliqi N, Blilie A, Ji X, ..., Kartasalo K, Eklund M
BMJ Open 15 (7) e097591 [2025-07-07; online 2025-07-07]
DDLS Fellow Kimmo Kartasalo
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In Situ Inference of Copy Number Variations in Image-Based Spatial Transcriptomics
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Genetic mapping in the red mason bee implicates ANTSR as an ancient sex-determining locus in bees and ants
Rönneburg T, Taliadoros D, Olsson A, ..., Seidelmann K, Webster MT
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Toll-like receptor 4 (TLR-4) polymorphisms and asthma risk in rural and urban settings: findings from the UK biobank.
Kisiel MA, Rask-Andersen M, Johansson Å, Ek WE, Rask-Andersen A
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Pairwise Attention: Leveraging Mass Differences to Enhance De Novo Sequencing of Mass Spectra.
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J. Proteome Res. 24 (7) 3722-3730 [2025-07-04; online 2025-06-02]
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From Recruitment to Retirement: Research Infrastructure Staff Views on the Diversification of Scientific Career Paths at Universities in Sweden in 2024.
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F1000Res 14 (-) 652 [2025-07-04; online 2025-07-04]
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Sci Adv 11 (27) eadv4558 [2025-07-04; online 2025-07-04]
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Shungube M, Reddy N, Ghazi T, ..., Govender T, Naicker T
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Brain macrophages and pial fibroblasts promote inflammation in a hypomyelination model.
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Acta Neuropathol Commun 13 (1) 145 [2025-07-04; online 2025-07-04]
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Highly Multiplexed Immunoassays for the Validation of Anti-GPCR Antibodies.
Bendes A, Dahl L, Sakmar TP, Schwenk JM, Kotliar IB
Methods in molecular biology (Clifton, N.J.) 2937 (-) 189-199 [2025-07-02; online 2025-07-02]
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Bladder cancer subtypes exhibit limited plasticity across different microenvironments and in metastases.
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Exp Hematol Oncol 14 (1) 91 [2025-07-02; online 2025-07-02]
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Survival and Quality of Life After Isolated Hepatic Perfusion With Melphalan as a Treatment for Uveal Melanoma Liver Metastases: Final Results From the Phase III Randomized Controlled Trial SCANDIUM.
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Quantification of Endogenous Steroids and Hormonal Contraceptives in Human Plasma via Surrogate Calibration and UHPLC-MS/MS.
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Anal. Chem. 97 (25) 13496-13503 [2025-07-01; online 2025-06-20]
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Otte LB, Hogstrand C, Mardinoglu A, Guo M
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Essén M, Franciskovic E, Sele C, Godzwon M, Ohlin M
Front Immunol 16 (-) 1600778 [2025-07-01; online 2025-07-01]
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High-throughput DNA melt measurements enable improved models of DNA folding thermodynamics.
Ke Y, Sharma E, Wayment-Steele HK, ..., Marklund E, Greenleaf WJ
Nat Commun 16 (1) 5572 [2025-07-01; online 2025-07-01]
Emil Marklund SciLifeLab Fellow
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Exploration of fecal microbiota in newly diagnosed patients with inflammatory bowel disease using shotgun metagenomics.
Orejudo M, Gómez MJ, Riestra S, ..., Gisbert JP, Chaparro M
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Elevated KRAS protein level is associated with better survival in pancreatic cancer.
Stålberg SM, Silwal-Pandit L, Hamfjord J, ..., Skålhegg BS, Kure EH
BMC Cancer 25 (1) 1080 [2025-07-01; online 2025-07-01]
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Divergence of Leptin Receptor and Interleukin-6 Receptor Subunit b in Early Vertebrate Evolution and Physiological Insights from the Sea Lamprey.
Gong N, Barany A, Norstog JL, ..., McCormick SD, Sheridan MA
Mol. Biol. Evol. 42 (7) - [2025-07-01; online 2025-07-01]
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Benchmarking the AI-based diagnostic potential of plasma proteomics for neurodegenerative disease in 17,170 people.
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medRxiv - (-) - [2025-07-01; online 2025-07-01]
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Activation of the ChvG-ChvI pathway promotes survival during cell wall stress in Agrobacterium tumefaciens.
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Mol. Biol. Cell 36 (7) ar84 [2025-07-01; online 2025-05-15]
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A high polygenic risk score is associated with SSA/SSB antibody positivity and early onset in primary Sjögren's disease.
Fugmann C, Reid S, Pucholt P, ..., Imgenberg-Kreuz J, Nordmark G
Rheumatology (Oxford) 64 (7) 4341-4346 [2025-07-01; online 2024-12-18]
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A genome-wide association study in 10,000 individuals links plasma N-glycome to liver disease and anti-inflammatory proteins.
Sharapov S, Timoshchuk A, Zaytseva O, ..., Lauc G, Aulchenko YS
Nat Commun 16 (1) 5525 [2025-07-01; online 2025-07-01]
Clemens Wittenbecher DDLS Fellow
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When numbers matter: Rethinking the role of gene duplication on short evolutionary timescales.
Lindstedt F, Zhou Q, Milesi P
American journal of botany 112 (7) e70072 [2025-07-00; online 2025-07-09]
Pascal Milesi SciLifeLab Fellow
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Uncemented hip arthroplasty and denosumab: increased postoperative dipeptide concentrations and identification of potential new bone turnover biomarkers.
Kultima K, Ashtiani SH, Erngren I, ..., Mallmin H, Hailer NP
JBMR Plus 9 (7) ziaf091 [2025-07-00; online 2025-05-19]
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UYSD: a novel data repository accessible via public website for worldwide population frequencies of Y-SNP haplogroups.
Ralf A, Zandstra D, van Wersch B, ..., Schneider PM, Kayser M
Eur. J. Hum. Genet. 33 (7) 904-912 [2025-07-00; online 2025-05-08]
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Tumor hypoxia shapes natural killer cell anticancer activities.
Retamal MA, Salazar-Onfray F, González FE, Tittarelli A
J. Mol. Med. 103 (7) 755-777 [2025-07-00; online 2025-05-30]
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The value of mental science: we publish what matters.
Malhi GS, Adlington K, Al-Diwani A, ..., Zisman-Ilani Y, Fernandez-Egea E
Br J Psychiatry 227 (1) 429-433 [2025-07-00; online 2025-06-09]
Erika Comasco SciLifeLab Fellow
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The spatiotemporal distribution of human pathogens in ancient Eurasia.
Sikora M, Canteri E, Fernandez-Guerra A, ..., Iversen AKN, Willerslev E
Nature 643 (8073) 1011-1019 [2025-07-00; online 2025-07-09]
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Systematically identification of survival-associated eQTLs in a Japanese kidney cancer cohort.
Song X, Jin H, Li X, ..., Zhang C, Mardinoglu A
PLoS Genet 21 (7) e1011770 [2025-07-00; online 2025-07-07]
Adil Mardinoglu SciLifeLab Fellow
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Structural and functional insights into extreme thermal stability and activity of two GH12 domains of a multidomain glycosidase from a hyperthermophilic euryarchaeon.
Zayulina KS, Frolov EN, Stracke C, ..., Shugaeva TE, Kublanov IV
FEBS J. 292 (14) 3771-3794 [2025-07-00; online 2025-04-21]
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Stepwise ATP translocation into the endoplasmic reticulum by human SLC35B1.
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Nature 643 (8072) 855-864 [2025-07-00; online 2025-05-21]
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Sex programs functional protein level dimorphism in the zebrafish gastrointestinal tract
Niksirat H, Siino V, Steinbach C, Levander F
Aquaculture Reports 42 (-) 102775 [2025-07-00; online 2025-07-00]
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Rescue of loss-of-function long QT syndrome-associated mutations in KV7.1/KCNE1 by the endocannabinoid N-arachidonoyl-L-serine (ARA-S).
Hiniesto-Iñigo I, Sridhar A, Louradour J, ..., Ottosson NE, Liin SI
Br J Pharmacol 182 (13) 2861-2877 [2025-07-00; online 2025-03-14]
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Plasma metabolite profiles of meat intake and their association with cardiovascular disease risk: A population-based study in Swedish cohorts.
Arage G, Dekkers KF, Rašo LM, ..., Fall T, Ahmad S
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Niu G, Toma MA, Geara J, ..., Sommar P, Xu Landén N
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SciLifeLab Fellow Simon Elsässer
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Glasgow RIC, Singh V, Peña-Pérez L, ..., Amunts A, Wredenberg A
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IEEE Comput Graph Appl 45 (5) 64-77 [2025-06-20; online 2025-06-20]
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Cell Commun. Signal 23 (1) 298 [2025-06-20; online 2025-06-20]
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Malmgren H, Kvarnung M, Gustafsson P, ..., Lindstrand A, Lagerstedt-Robinson K
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Hellbacher E, van Hoef V, Johansson A, ..., Rantapää-Dahlqvist S, Dahlqvist J
Front Immunol 16 (-) 1600754 [2025-06-18; online 2025-06-18]
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Mol Ther Oncol 33 (2) 200954 [2025-06-18; online 2025-02-20]
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ACS Chem Neurosci 16 (12) 2295-2311 [2025-06-18; online 2025-05-15]
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Genome Med 17 (1) 68 [2025-06-17; online 2025-06-17]
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Fossi MC, Limonta G, Baini M, ..., Rosso M, Panti C
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Panara V, Arnold H, Gloger M, ..., Smialowska A, Koltowska K
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Valli D, Ooi SA, Kaya I, ..., Andrén PE, Maj M
Biochemistry 64 (12) 2583-2595 [2025-06-17; online 2025-05-26]
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Maheshwari A, Dookie R, Gaytán MO, Henriques-Normark B, Sotiriou GA
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Olof Eriksson SciLifeLab Fellow
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Sato K, Lyu J, van den Berg J, ..., Elsässer SJ, Knipscheer P
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SciLifeLab Fellow Simon Elsässer
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Kehler M, Zhou K, Kemas AM, ..., Lauschke VM, Michel M
Chemistry 31 (33) e202500382 [2025-06-12; online 2025-05-15]
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Deep plasma proteomics identifies and validates an eight-protein biomarker panel that separate benign from malignant tumors in ovarian cancer.
Moskov M, Hedlund Lindberg J, Lycke M, ..., Stålberg K, Enroth S
Commun Med (Lond) 5 (1) 230 [2025-06-12; online 2025-06-12]
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Genomic insights into the genetic basis of the seed size and weight revealed by the Chinese peanut key landraces.
Wang J, Jiao B, Qu C, ..., Li C, Shan S
Theor Appl Genet 138 (7) 144 [2025-06-11; online 2025-06-11]
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Moraes Zenker M, Portella TP, Pessoa FAC, Bengtsson-Palme J, Galetti PM
Sci Rep 15 (1) 20045 [2025-06-11; online 2025-06-11]
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Revised Diffusion Law Permits Quantitative Nanoscale Characterization of Membrane Organization.
Svobodová B, Št'astný D, Blom H, ..., Hof M, Šachl R
Anal. Chem. 97 (22) 11478-11485 [2025-06-10; online 2025-05-29]
Erdinc Sezgin SciLifeLab Fellow
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Flame-Made Doped Iron Oxide Nanoparticles as Tracers for Magnetic Particle Imaging.
Ansari SR, Imhoff ED, Suárez-López YDC, ..., Rinaldi-Ramos CM, Teleki A
Chem Mater 37 (11) 4071-4084 [2025-06-10; online 2025-05-20]
Alexandra Teleki SciLifeLab Fellow
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The burning glass effect of water droplets triggers a high light-induced calcium response in the chloroplast stroma.
Kuang D, Romand S, Zvereva AS, ..., Costa A, Stael S
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Li Q, Wiita E, Helleday T, Bryant P
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DDLS Fellow Patrick Bryant
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Contrasting Becker and Duchenne muscular dystrophy serum biomarker candidates by using data independent acquisition LC-MS/MS.
Johansson C, Schrama EJ, Kotol D, ..., Spitali P, Al-Khalili Szigyarto C
Skelet Muscle 15 (1) 15 [2025-06-07; online 2025-06-07]
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Disruption of undecaprenyl phosphate recycling suppresses ampC beta-lactamase induction in Pseudomonas aeruginosa
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Prusty BM, Srimayee S, Karn R, ..., Winterhalter M, Manna D
Chemistry 31 (31) e202501013 [2025-06-03; online 2025-04-27]
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Quantitative Mass Spectrometry Imaging Protocols for Spatially Heterogeneous Samples.
Shariatgorji R, Niehues M, Nilsson A, ..., Svenningsson P, Andrén PE
Anal. Chem. 97 (21) 10957-10961 [2025-06-03; online 2025-05-22]
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Pooled optical screening in bacteria using chromosomally expressed barcodes.
Soares RRG, García-Soriano DA, Larsson J, ..., Nilsson M, Elf J
Commun Biol 8 (1) 851 [2025-06-03; online 2025-06-03]
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Pathway activation model for personalized prediction of drug synergy.
Trac QT, Huang Y, Erkers T, ..., Pawitan Y, Vu TN
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Pathway activation model for personalized prediction of drug synergy
Trac QT, Huang Y, Erkers T, ..., Pawitan Y, Vu TN
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Evaluation of automatic cell free DNA extraction metrics using different blood collection tubes.
Andersson D, Kristiansson H, Luna Santamaría M, ..., Torinsson Naluai Å, Ståhlberg A
Sci Rep 15 (1) 19364 [2025-06-03; online 2025-06-03]
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Visnes T, Zhou K, Kemas AM, ..., Lauschke VM, Michel M
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A resource for whole-body gene expression map of human tissues based on integration of single cell and bulk transcriptomics.
Shi M, Méar L, Karlsson M, ..., Uhlén M, Zhang C
Genome Biol. 26 (1) 152 [2025-06-03; online 2025-06-03]
Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow
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Wastewater surveillance of SARS-CoV-2 from aircraft to citywide monitoring.
Perez-Zabaleta M, Berg C, Latorre-Margalef N, ..., Hugerth LW, Cetecioglu Z
Nat Commun 16 (1) 5125 [2025-06-02; online 2025-06-02]
DDLS Fellow Luisa Hugerth
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ColBuilder: flexible structure generation of crosslinked collagen fibrils.
Monego D, Brosz M, Buck J, ..., Sugita Y, Gräter F
Bioinformatics 41 (6) - [2025-06-02; online 2025-05-05]
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BiGSM: Bayesian inference of gene regulatory network via sparse modelling.
Qin H, Garbulowski M, Sonnhammer ELL, Chatterjee S
Bioinformatics 41 (6) - [2025-06-02; online 2025-06-09]
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A Biological-Systems-Based Analyses Using Proteomic and Metabolic Network Inference Reveals Mechanistic Insights into Hepatic Lipid Accumulation: An IMI-DIRECT Study.
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medRxiv - (-) - [2025-06-02; online 2025-06-02]
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Behrendt-Møller I, Vomstein TK, Pereira M, ..., Hugerth LW, Nielsen HS
Hum. Reprod. 40 (Supplement_1) - [2025-06-01; online 2025-06-23]
DDLS Fellow Luisa Hugerth
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P-129 Oxygen levels alter energy metabolism in bovine preimplantation embryos
Boskovic N, Ivask M, Yazgeldi Gunaydin G, ..., Daub CO, Kere J
Hum. Reprod. 40 (Supplement_1) - [2025-06-01; online 2025-06-23]
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Effects of the choice of the continuous phase in droplet microfluidics on internal particle manipulation with acoustophoresis.
Shi Q, Baasch T, Liu Z, ..., Barbe L, Tenje M
J Acoust Soc Am 157 (6) 4262-4272 [2025-06-01; online 2025-06-06]
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YCharOS protocol for antibody validation.
Monteiro FL, Voskuil JLA, Williams C
Nat Protoc 20 (6) 1389-1390 [2025-06-00; online 2024-12-18]
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What does oxidative stress look like? Visualizing expression of redox-associated proteins with imaging-based spatial proteomics
Sigaeva A, Gnann C, Lundberg E
Free Radic. Biol. Med. 233 (-) S69 [2025-06-00; online 2025-06-00]
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Vestibular modulation by stimulant derivatives in a pentameric ligand-gated ion channel.
Karlsson E, Andén O, Fan C, ..., Delarue M, Lindahl E
Br J Pharmacol 182 (12) 2790-2802 [2025-06-00; online 2025-03-11]
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Using TCR-CAR dual signaling for precise cancer targeting.
Shahbazy M, Leo IR, Faridi P, Caron E
Trends Immunol. 46 (6) 435-437 [2025-06-00; online 2025-05-13]
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Trajectories and dimensional phenotypes of depressive symptoms throughout pregnancy and postpartum in relation to prior premenstrual symptoms.
Schleimann-Jensen E, Sundström-Poromaa I, Meltzer-Brody S, ..., Skalkidou A, Comasco E
Br J Psychiatry 226 (6) 401-409 [2025-06-00; online 2025-06-20]
Erika Comasco SciLifeLab Fellow
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Toward clinical long-read genome sequencing for rare diseases.
Eisfeldt J, Ek M, Nordenskjöld M, Lindstrand A
Nat. Genet. 57 (6) 1334-1343 [2025-06-00; online 2025-05-07]
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The blood response to subway-derived iron nanoparticles.
Ekdahl KN, Monie L, Juárez-Facio AT, ..., Nilsson B, Fromell K
Environ Toxicol Pharmacol 116 (-) 104717 [2025-06-00; online 2025-05-14]
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Subjective, behavioural and physiological correlates of stress in women using hormonal contraceptives.
Bürger Z, Kordowich C, Kübbeler J, ..., Derntl B, Kogler L
Br J Psychiatry 226 (6) 392-400 [2025-06-00; online 2025-06-13]
Erika Comasco SciLifeLab Fellow
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Shaping the future of precision medicine: plasma proteomics to uncover insights in thrombosis.
Johansson E, Iglesias MJ, Odeberg J, Edfors F
Expert Rev Proteomics 22 (6) 237-254 [2025-06-00; online 2025-06-13]
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Resolving the conformational ensemble of a membrane protein by integrating small-angle scattering with AlphaFold.
Lidbrink SE, Howard RJ, Haloi N, Lindahl E
PLoS Comput Biol 21 (6) e1013187 [2025-06-00; online 2025-06-27]
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Drouin-Ouellet J, Lopes M, Pereira CF
Cell Reprogram 27 (3) 95-101 [2025-06-00; online 2025-05-20]
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Psychiatric symptoms on the ovarian hormone roller-coaster.
Comasco E, Epperson CN, Kulkarni J
Br J Psychiatry 226 (6) 329-330 [2025-06-00; online 2025-06-18]
Erika Comasco SciLifeLab Fellow
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Proteomic signatures for fibrosis in MASLD: a biopsy-proven dual-cohort study.
Blomdahl J, Åberg M, Fridén M, ..., Ekstedt M, Vessby J
Scand. J. Gastroenterol. 60 (6) 597-605 [2025-06-00; online 2025-04-16]
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Preserving Neuronal Chemical Messengers: Heat Stabilization Versus Snap Freezing for Improved MALDI Mass Spectrometry Imaging of Brain Tissues.
Salviati E, Luptáková D, Nilsson A, ..., Roman E, Andrén PE
J. Neurochem. 169 (6) e70122 [2025-06-00; online 2025-06-16]
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Kämpe A, Gudmundsson S, Walsh CP, ..., Lindstrand A, Lappalainen T
Nat. Med. 31 (6) 1730-1732 [2025-06-00; online 2025-04-05]
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Postdiagnosis physical activity and dietary inflammatory and insulinemic potential with overall survival in men with nonmetastatic prostate cancer.
Lee DH, Rezende LFM, Ferrari G, ..., Mucci LA, Giovannucci EL
Eur. J. Epidemiol. 40 (6) 669-679 [2025-06-00; online 2025-05-28]
DDLS Fellow Qiaoli Wang
PubMed DOI Crossref
Occurrence and risks of pharmaceuticals in Mahdia's coastline (Tunisia): distribution, antibiotic resistance, and ecotoxicological impact.
Fenni F, Sunyer-Caldú A, Mansour HB, Diaz-Cruz MS
Environ Sci Pollut Res Int 32 (30) 18419-18433 [2025-06-00; online 2025-07-24]
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NAT2 activity increases cytotoxicity of anthracycline antibiotics and HDAC inhibitors.
Rameika N, Tsiara I, Zhang X, ..., Globisch D, Sjöblom T
Biochim Biophys Acta Mol Basis Dis 1871 (5) 167755 [2025-06-00; online 2025-03-13]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
Multimorbidity patterns and blood biomarkers of Alzheimer's disease in community-dwelling cognitively unimpaired older adults.
Marengoni A, Grande G, Valletta M, ..., Winblad B, Vetrano DL
Alzheimers Dement 21 (6) e70411 [2025-06-00; online 2025-06-23]
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Multimodal cell maps as a foundation for structural and functional genomics.
Schaffer LV, Hu M, Qian G, ..., Lundberg E, Ideker T
Nature 642 (8066) 222-231 [2025-06-00; online 2025-04-09]
PubMed DOI Crossref
Magnetic microfiber hyperthermia for synergistic antimicrobial activity against methicillin-resistant Staphylococcus aureus.
Ansari SR, Grimm D, Ramachandran RV, ..., Sotiriou GA, Teleki A
Mater Today Bio 32 (-) 101862 [2025-06-00; online 2025-05-12]
Alexandra Teleki SciLifeLab Fellow
PubMed DOI Crossref
Large-scale network analysis of the cerebrospinal fluid proteome identifies molecular signatures of frontotemporal lobar degeneration.
Saloner R, Staffaroni AM, Dammer EB, ..., Casaletto KB, ALLFTD Consortium
Nat Aging 5 (6) 1143-1158 [2025-06-00; online 2025-05-16]
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Green Listed v2.0: A Web Application for Streamlined Design of Custom CRISPR Screens.
Henkel E, Li Z, Uvehag D, ..., Henkel M, Wermeling F
CRISPR J 8 (3) 216-223 [2025-06-00; online 2025-05-07]
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Genome-wide analyses identify 30 loci associated with obsessive-compulsive disorder.
Strom NI, Gerring ZF, Galimberti M, ..., Derks EM, Mattheisen M
Nat. Genet. 57 (6) 1389-1401 [2025-06-00; online 2025-05-13]
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Genetically Determined Inflammation-Related Proteins in Asthma and Type-2 Signatures.
Hernandez-Pacheco N, Björkander S, Merid SK, ..., Schwenk JM, Melén E
Allergy 80 (6) 1702-1714 [2025-06-00; online 2025-06-04]
PubMed DOI Crossref
Genetic liability for anxiety and treatment response to the monoamine stabilizer OSU6162 in alcohol dependence: a retrospective secondary analysis.
Hong MG, Khemiri L, Guterstam J, ..., Jayaram-Lindström N, Melas PA
Pharmacol Rep 77 (3) 840-849 [2025-06-00; online 2025-03-12]
PubMed DOI Crossref
Frequent Hybridisation Between Parapatric Lekking Bird-of-Paradise Species.
Thörn F, Müller IA, Soares AER, ..., Blom MPK, Irestedt M
Mol. Ecol. 34 (11) e17780 [2025-06-00; online 2025-04-29]
PubMed DOI Crossref
Fish are poor sentinels for surveillance of riverine antimicrobial resistance.
Tskhay F, Köbsch C, Elena AX, ..., Berendonk TU, Klümper U
One Health 20 (-) 101026 [2025-06-00; online 2025-04-01]
DDLS Fellow
PubMed DOI Crossref
Enduring modulation of dorsal raphe nuclei regulates (R,S)-ketamine-mediated resilient stress-coping behavior.
Camargo A, Nilsson A, Shariatgorji R, ..., Andren PE, Svenningsson P
Mol. Psychiatry 30 (6) 2504-2516 [2025-06-00; online 2024-11-26]
PubMed DOI Crossref
Emerging multi-drug resistant and extended-spectrum β-lactamase (ESBL)-positive enterotoxigenic E. coli (ETEC) clones circulating in aquatic environments and in patients.
Joffré E, Martín-Rodríguez AJ, Justh de Neczpal A, von Mentzer A, Sjöling Å
One Health 20 (-) 100968 [2025-06-00; online 2025-01-10]
Astrid von Mentzer DDLS Fellow
PubMed DOI Crossref
Emergency critical care - life-saving critical care before ICU admission: A consensus statement of a Group of European Experts.
Dünser MW, Leach R, Al-Haddad M, ..., Behringer W, Critical Care in Emergency Medicine Interest Group
J Crit Care 87 (-) 155035 [2025-06-00; online 2025-02-05]
PubMed DOI Crossref
Direct and indirect pathways linking the Lon protease to motility behaviors in the pathogen Pseudomonas aeruginosa.
Kallazhi A, Rahman A, Römling U, Jonas K
PLoS Pathog 21 (6) e1013288 [2025-06-00; online 2025-06-25]
Kristina Jonas SciLifeLab Fellow
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Diel Bacterioplankton Community Dynamics Under Contrasting Light Regimes.
Papadopoulou S, Linkhorst A, Balmonte JP, ..., Bertilsson S, Székely AJ
Environ Microbiol Rep 17 (3) e70099 [2025-06-00; online 2025-05-09]
DOI Crossref
Control of redox signaling by TXNRD1 studied at single cell level
Scholzen KC, Zeisel L, Diekmann C, ..., Ziegenhain C, Arnér ESJ
Free Radic. Biol. Med. 233 (-) S15-S16 [2025-06-00; online 2025-06-00]
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Blood-based biomarkers of Alzheimer's disease and incident dementia in the community.
Grande G, Valletta M, Rizzuto D, ..., Fratiglioni L, Vetrano DL
Nat. Med. 31 (6) 2027-2035 [2025-06-00; online 2025-03-26]
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Bioinspired Nanochitin-Based Porous Constructs for Light-Driven Whole-Cell Biotransformations.
Arumughan V, Medipally H, Torris A, ..., Kourist R, Kontturi E
Adv. Mater. Weinheim 37 (22) e2413058 [2025-06-00; online 2025-02-03]
PubMed DOI Crossref
Bacterial transcriptional repressor NrdR - a flexible multifactorial nucleotide sensor.
Rozman Grinberg I, Bimaï O, Shahid S, ..., Sjöberg BM, Logan DT
FEBS J. 292 (12) 3091-3112 [2025-06-00; online 2025-03-03]
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AI-first structural identification of pathogenic protein target interfaces.
Saluri M, Landreh M, Bryant P
PLoS Comput Biol 21 (6) e1013168 [2025-06-00; online 2025-06-26]
DDLS Fellow Patrick Bryant
PubMed DOI Crossref
A universal language for finding mass spectrometry data patterns.
Damiani T, Jarmusch AK, Aron AT, ..., Dorrestein PC, Wang M
Nat. Methods 22 (6) 1247-1254 [2025-06-00; online 2025-05-12]
Daniel Globisch SciLifeLab Fellow
DOI Crossref
329 | CIRCULATING PROTEIN BIOMARKERS CAN AID DIFFERENTIAL DIAGNOSIS OF PRIMARY CNS LYMPHOMAS AND GLIOMAS
Babačić H, Chowdhury NM, Niemi J, ..., Glimelius I, Hellström M
Hematological Oncology 43 (S3) - [2025-06-00; online 2025-06-16]
PubMed DOI Crossref
No evidence of transposable element bursts in the Galápagos Scalesia adaptive radiation despite hybridization, diversification and ecological niche shifts.
Cerca J, Díaz PJ, Goubert C, ..., Rieseberg LH, Martin MD
Mobile DNA 16 (1) 23 [2025-05-31; online 2025-05-31]
DDLS Fellow José Cerca
PubMed DOI Crossref
Human LY9 governs CD4+ T cell IFN-γ immunity to Mycobacterium tuberculosis.
Ogishi M, Puchan J, Yang R, ..., Boisson-Dupuis S, Casanova JL
Sci Immunol 10 (107) eads7377 [2025-05-30; online 2025-05-30]
PubMed DOI Crossref
Comprehensive transcriptome assessment in PBMCs of post-COVID patients at a median follow-up of 28 months after a mild COVID infection reveals upregulation of JAK/STAT signaling and a prolonged immune response.
Fineschi S, Klar J, Lopez Egido JR, ..., Kaden R, Dahl N
Front Immunol 16 (-) 1589589 [2025-05-30; online 2025-05-30]
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KRIT1 heterozygous mutations are sufficient to induce a pathological phenotype in patient-derived iPSC models of cerebral cavernous malformation.
Arce M, Erzar I, Yang F, ..., Latini R, Magnusson PU
Cell Reports 44 (5) 115576 [2025-05-27; online 2025-04-14]
DOI Crossref
Accumulation of a biparentally-inherited Neptune transposable element in natural Killifish hybrids ( Fundulus diaphanus × F. heteroclitus )
Roussel AJ, Suh A, Ruiz-Ruano FJ, Dion-Côté AM
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Widespread potential for phototrophy and convergent reduction of lifecycle complexity in the dimorphic order Caulobacterales
Hallgren J, Dharamshi JE, Rodríguez-Gijón A, ..., Garcia SL, Jonas K
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Kristina Jonas Sarahi Garcia SciLifeLab Fellow
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Environmental reservoir of resistance genes for the last resort antibiotic Cefiderocol
Gschwind R, Bonnet M, Abramova A, ..., Bengtsson-Palme J, Ruppe E
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DDLS Fellow
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1000 conifer genomes: Genome innovation, organisation and diversity
Nilsson O, Kalman TA, Delhomme N, ..., Nystedt B, Street N
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DDLS Fellow Tom van der Valk
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Age and Alzheimer's disease affect functional connectivity along separate axes of functional brain organization.
Rittmo J, Franzmeier N, Strandberg O, ..., Hansson O, Vogel JW
bioRxiv - (-) - [2025-05-25; online 2025-05-25]
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RareFold: Structure Prediction and Design of Proteins with Noncanonical Amino Acids
Li Q, Daumiller D, Zuo F, ..., Pan-Hammarström Q, Bryant P
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DDLS Fellow Patrick Bryant
DOI Crossref
From Structure to Immunogenicity: Decoding Correlated Dynamics at the Peptide MHC interface to Understand TCR Recognition
Resink T, Sala BM, Sun R, ..., Ljunggren HG, Achour A
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Library-based single-cell analysis of CAR signaling reveals drivers of in vivo persistence.
Perez CR, Garmilla A, Nilsson A, ..., Lauffenburger DA, Birnbaum ME
Cell Syst 16 (5) 101260 [2025-05-21; online 2025-04-10]
Avlant Nilsson DDLS Fellow
PubMed DOI Crossref
Data of the Insect Biome Atlas: a metabarcoding survey of the terrestrial arthropods of Sweden and Madagascar.
Miraldo A, Sundh J, Iwaszkiewicz-Eggebrecht E, ..., Roslin T, Ronquist F
Sci Data 12 (1) 835 [2025-05-21; online 2025-05-21]
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Association of matrix metalloproteinase 7 and the alpha-chain of fibrinogen at baseline with response to methotrexate at 3 months in patients with early rheumatoid arthritis.
Hambardzumyan K, Hamsten C, Lourido L, ..., Jakobsson PJ, Idborg H
BMC Rheumatol 9 (1) 56 [2025-05-21; online 2025-05-21]
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The ACBD3 protein coordinates ER-Golgi contacts to enable productive TBEV infection.
Yau W-L, Peters MBA, Rönfeldt S, ..., Överby AK, Lundmark R
J. Virol. 99 (5) e0222424 [2025-05-20; online 2025-04-10]
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Pathway activation model for personalized prediction of drug synergy
Trac QT, Huang Y, Erkers T, ..., Pawitan Y, Vu TN
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Error in Affiliations.
JAMA 333 (19) 1733 [2025-05-20; online 2025-04-23]
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Caveolin assemblies displace one bilayer leaflet to organize and bend membranes.
Doktorova M, Daum S, Reagle TR, ..., Kenworthy AK, Levental I
Proc. Natl. Acad. Sci. U.S.A. 122 (20) e2417024122 [2025-05-20; online 2025-05-13]
DDLS Fellow Milka Doktorova
PubMed DOI Crossref
Machine Learning for Toxicity Prediction Using Chemical Structures: Pillars for Success in the Real World.
Seal S, Mahale M, García-Ortegón M, ..., Carpenter AE, Bender A
Chem. Res. Toxicol. 38 (5) 759-807 [2025-05-19; online 2025-05-02]
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Inkjet-Printed Graphene Multielectrode Arrays: An Accessible Platform for In Vitro Cardiac Electrophysiology.
Lumpuy-Castillo J, Fu Y, Avila Ramirez AE, ..., Zeglio E, Garma LD
ACS Appl Bio Mater 8 (5) 3708-3716 [2025-05-19; online 2025-04-26]
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Gender differences in global antimicrobial resistance.
Salehi M, Laitinen V, Bhanushali S, ..., Pärnänen K, Lahti L
NPJ Biofilms Microbiomes 11 (1) 79 [2025-05-19; online 2025-05-19]
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PubMed DOI Crossref
Genetic Isolation among Four Lineages of Silene nutans.
Postel Z, Martin H, Roux C, ..., Vekemans X, Touzet P
Plant Cell Physiol. 66 (4) 514-528 [2025-05-17; online 2024-09-26]
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Modelling Population-Level Hes1 Dynamics: Insights from a Multi-framework Approach.
Menz G, Engblom S
Bull. Math. Biol. 87 (6) 74 [2025-05-16; online 2025-05-16]
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Chromosome-level genome assembly of Norwegian wild alpine reindeer ( Rangifer tarandus tarandus )
Tørresen OK, Tooming-Klunderud A, Skage M, ..., Mysterud A, Jakobsen KS
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DDLS Fellow José Cerca
PubMed DOI Crossref
Cell shapes decode molecular phenotypes in image-based spatial proteomics.
Le T, Leineweber WD, Viana MP, ..., Rafelski SM, Lundberg E
bioRxiv - (-) - [2025-05-16; online 2025-05-16]
DDLS Fellow Wei Ouyang
PubMed DOI Crossref
Uracil-induced replication stress drives mutations, genome instability, anti-cancer treatment efficacy, and resistance.
Mortusewicz O, Haslam J, Gad H, Helleday T
Mol. Cell 85 (10) 1897-1906 [2025-05-15; online 2025-05-17]
PubMed DOI Crossref
Ribosomes modulate transcriptome abundance via generalized frameshift and out-of-frame mRNA decay.
Zhang Y, Nersisyan L, Fürst E, ..., Piazza I, Pelechano V
Mol. Cell 85 (10) 2017-2031.e7 [2025-05-15; online 2025-05-17]
SciLifeLab Fellow
PubMed DOI Crossref
Nanoscale DNA tracing reveals the self-organization mechanism of mitotic chromosomes.
Beckwith KS, Brunner A, Morero NR, Jungmann R, Ellenberg J
Cell 188 (10) 2656-2669.e17 [2025-05-15; online 2025-03-24]
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Cyanobacterial Argonautes and Cas4 family nucleases cooperate to interfere with invading DNA.
Bobadilla Ugarte P, Halter S, Mutte SK, ..., Westphal AH, Swarts DC
Mol. Cell 85 (10) 1920-1937.e10 [2025-05-15; online 2025-04-26]
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Connecting Academia and Industry Through Communities of Practice in the Informatics Domain.
Peltonen LM, Gaudet-Blavignac C, Lindsköld L, Hofdijk J
Stud Health Technol Inform 327 (-) 303-307 [2025-05-15; online 2025-05-17]
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Community-promoted antibiotic resistance genes show increased dissemination among pathogens
Lund D, Johnning A, Holmström M, ..., Bengtsson-Palme J, Kristiansson E
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DDLS Fellow
PubMed DOI Crossref
Cell membranes sustain phospholipid imbalance via cholesterol asymmetry.
Doktorova M, Symons JL, Zhang X, ..., Levental KR, Levental I
Cell 188 (10) 2586-2602.e24 [2025-05-15; online 2025-04-02]
DDLS Fellow Erdinc Sezgin Milka Doktorova SciLifeLab Fellow
PubMed DOI Crossref
A systematic implementation of padlock probing-based rolling circle amplification in an integrated microfluidic device for quantitative biomolecular analyses.
Caneira CRF, Rosa RR, Chu V, ..., Soares RRG, Conde JP
Anal. Chim. Acta 1351 (-) 343834 [2025-05-15; online 2025-02-23]
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Uridine cytidine kinases dictate the therapeutic response of molnupiravir via its bioactivation
Shu H, Sharm S, Alam S, ..., Rudd SG, Zhang SM
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PubMed DOI Crossref
Revised phylogeny of mouflon based on expanded sampling of mitogenomes.
Mereu P, Pirastru M, Morell Miranda P, ..., Günther T, Leoni GG
PLoS ONE 20 (5) e0323354 [2025-05-14; online 2025-05-14]
PubMed DOI Crossref
Metagenomic biodiversity assessment within an offshore wind farm.
Serivichyaswat PT, Scholte T, Wilms T, Stranddorf L, van der Valk T
Sci Rep 15 (1) 16786 [2025-05-14; online 2025-05-14]
DDLS Fellow Tom van der Valk
PubMed DOI Crossref
Extensively acquired antimicrobial-resistant bacteria restructure the individual microbial community in post-antibiotic conditions.
Baek JW, Lim S, Park N, ..., Koh A, Lee S
NPJ Biofilms Microbiomes 11 (1) 78 [2025-05-14; online 2025-05-14]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
DOI Crossref
AI4CellFate: Interpretable Early Cell Fate Prediction with Generative AI
Cunha I, Panconi L, Bauer S, ..., Le Marois A, Griffié J
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DDLS Fellow Juliette Griffie
PubMed DOI Crossref
The developmental factor TBX3 engages with the Wnt/β-catenin transcriptional complex in colorectal cancer to regulate metastasis genes.
Jauregi-Miguel A, Söderholm S, Weiss T, ..., Sheng G, Cantù C
Proc. Natl. Acad. Sci. U.S.A. 122 (19) e2419691122 [2025-05-13; online 2025-05-09]
DOI Crossref
Plasma membrane labelling efficiency, internalization and partitioning of functionalized fluorescent lipids as a function of lipid structure
Sezgin E
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Erdinc Sezgin SciLifeLab Fellow
DOI Crossref
Molecular insights into nucleocapsid assembly and transport in Marburg and Ebola viruses
Takamatsu Y, Dolnik O, Hirabayashi A, ..., Harumi CO, Noda T
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PubMed DOI Crossref
Loss of lipid asymmetry facilitates plasma membrane blebbing by decreasing membrane lipid packing.
Wang HY, Rumin A, Doktorova M, ..., Levental KR, Levental I
Proc. Natl. Acad. Sci. U.S.A. 122 (19) e2417145122 [2025-05-13; online 2025-05-05]
DDLS Fellow Milka Doktorova
DOI Crossref
Elevated KRAS protein level is associated with better survival in pancreatic cancer
Stålberg SM, Silwal-Pandit L, Hamfjord J, ..., Skålhegg BS, Kure EH
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PubMed DOI Crossref
Combining spatial transcriptomics with tissue morphology.
Chelebian E, Avenel C, Wählby C
Nat Commun 16 (1) 4452 [2025-05-13; online 2025-05-13]
PubMed DOI Crossref
Combining live fluorescence imaging with in situ cryoelectron tomography sheds light on the septation process in Deinococcus radiodurans.
Gaifas L, Kleman JP, Lacroix F, ..., Gutsche I, Timmins J
Proc. Natl. Acad. Sci. U.S.A. 122 (19) e2425047122 [2025-05-13; online 2025-05-06]
DOI Crossref
Proximity proteomics of primary cilia in human hypothalamic neurons
Macarelli V, Sroka TJ, Hansen JN, ..., Mick DU, Merkle FT
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PubMed DOI Crossref
Correction: Senataxin prevents replicative stress induced by the Myc oncogene.
Sberna S, Filipuzzi M, Bianchi N, ..., Curti L, Campaner S
Cell Death Dis 16 (1) 377 [2025-05-12; online 2025-05-12]
DOI Crossref
Chemically Recyclable and Enzymatically Degradable Thermostable Polyesters with Inherent Strain from α-Pinene-Derived Chiral Diols
Ranjani G, Subramaniyan S, Lopez-Lorenzo X, Hakkarainen M, Syrén PO
ACS Sustainable Chem. Eng. 13 (18) 6696-6705 [2025-05-12; online 2025-04-25]
DOI Crossref
Bridging 3D Molecular Structures and Artificial Intelligence by a Conformation Description Language
Xiong J, Shi Y, Zhang W, ..., Xiong Z, Zheng M
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PubMed DOI Crossref
The effectiveness of selection in a species affects the direction of amino acid frequency evolution.
McShea H, Wheeler AL, Goodman P, ..., Huttley G, Masel J
bioRxiv - (-) - [2025-05-10; online 2025-05-10]
DDLS Fellow Jennifer James
PubMed DOI Crossref
Phenotypic drug susceptibility testing for Mycobacterium tuberculosis variant bovis BCG in 12 hours.
Tran BM, Larsson J, Grip A, Karempudi P, Elf J
Nat Commun 16 (1) 4366 [2025-05-10; online 2025-05-10]
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Streamlining Multiplexed Tissue Image Analysis with PIPΣX: An Integrated Automated Pipeline for Image Processing and EXploration for Diverse Tissue Types.
Mardamshina M, Navarro FB, Casals AM, ..., Wählby C, Lundberg E
bioRxiv - (-) - [2025-05-09; online 2025-05-09]
PubMed DOI Crossref
Multiplex quantification of endocrine proteins in volumetric dried blood spots.
Stauch W, Olausson J, Bendes A, Beck O, Schwenk JM
Clin Proteomics 22 (1) 18 [2025-05-09; online 2025-05-09]
PubMed DOI Crossref
Mechanisms of autoimmune-mediated paraneoplastic syndromes: immune tolerance and disease pathogenesis.
Pérez-Bucio C, Behere A, Landegren N
Front Immunol 16 (-) 1608934 [2025-05-09; online 2025-05-09]
PubMed DOI Crossref
Evaluation of unsupervised learning algorithms for the classification of behavior from pose estimation data.
Mlost J, Dawli R, Liu X, Costa AR, Pollak Dorocic I
Patterns (N Y) 6 (5) 101237 [2025-05-09; online 2025-04-22]
Iskra Pollak Dorocic SciLifeLab Fellow
PubMed DOI Crossref
The Central Role of Ribosomal Proteins in p53 Regulation.
Lindström MS
Cancers (Basel) 17 (10) - [2025-05-08; online 2025-05-08]
PubMed DOI Crossref
INLAomics for Scalable and Interpretable Spatial Multiomic Data Integration.
Arnroth L, Vickovic S
bioRxiv - (-) - [2025-05-08; online 2025-05-08]
Sanja Vickovic SciLifeLab Fellow
PubMed DOI Crossref
Genome-wide association study of myocarditis and pericarditis following COVID-19 vaccination.
Cavalli M, Eriksson N, Baron T, ..., Hallberg P, Wadelius M
NPJ Vaccines 10 (1) 88 [2025-05-08; online 2025-05-08]
PubMed DOI Crossref
Challenging the "Undruggable"─Targeting STAT3 but Identifying Potent TrkA-Targeted Inhibitors.
Iliev P, McCutcheon C, Admas TH, ..., Frank DA, Page BDG
J Med Chem 68 (9) 9501-9524 [2025-05-08; online 2025-04-17]
DOI Crossref
Adapter dilution and input optimization for Qiagen QIAseq miRNA Library kit
Hasby F, Bachmann J, Wang C, Contreras-Lopez O, Mezger A
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PubMed DOI Crossref
Topology-based metrics for finding the optimal sparsity in gene regulatory network inference.
Lundqvist N, Garbulowski M, Hillerton T, Sonnhammer ELL
Bioinformatics 41 (5) - [2025-05-06; online 2025-03-24]
PubMed DOI Crossref
De novo clustering of large long-read transcriptome datasets with isONclust3.
Petri AJ, Sahlin K
Bioinformatics 41 (5) - [2025-05-06; online 2025-04-23]
Kristoffer Sahlin SciLifeLab Fellow
PubMed DOI Crossref
Antisense-mediated regulation of exon usage in the elastic spring region of Titin modulates sarcomere function.
Celik S, Hyrefelt L, Czuba T, ..., Smith JG, Gidlöf O
Cardiovasc Res 121 (4) 629-642 [2025-05-06; online 2025-03-05]
DOI Crossref
Single-Shot Design of a Cyclic Peptide Inhibitor of HIV-1 Membrane Fusion with EvoBind
Daumiller D, Giammarino F, Li Q, ..., Ceña Diez R, Bryant P
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DDLS Fellow Patrick Bryant
PubMed DOI Crossref
Oligodendroglia vulnerability in the human dorsal striatum in Parkinson's disease.
Barba-Reyes JM, Harder L, Marco Salas S, ..., Serrano-Pozo A, Muñoz-Manchado AB
Acta Neuropathol. 149 (1) 46 [2025-05-05; online 2025-05-05]
DOI Crossref
Limits of deep-learning-based RNA prediction methods
Ludaic M, Elofsson A
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DOI Crossref
Gene regulatory networks linked to GABA signalling emerge as relevant for glioblastoma pathogenesis
Nissen I, Dakhel S, Chakraborty C, ..., Erdem C, Remeseiro S
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Cemal Erdem DDLS Fellow
PubMed DOI Crossref
Unexpectedly low recombination rates and presence of hotspots in termite genomes.
Everitt T, Rönneburg T, Elsner D, ..., Korb J, Webster MT
Genome Res 35 (5) 1124-1137 [2025-05-02; online 2025-05-02]
DOI Crossref
Spatial transcriptomics and genetically implicated genes identify putative causal tissue structures for complex traits
Kvastad L, Kollotzek A, Saghaleyni R, ..., Cao T, Lappalainen T
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PubMed DOI Crossref
Open-Source and FAIR Research Software for Proteomics.
Perez-Riverol Y, Bittremieux W, Noble WS, ..., Käll L, Fondrie WE
J. Proteome Res. 24 (5) 2222-2234 [2025-05-02; online 2025-04-23]
PubMed DOI Crossref
Mosaic loss of Y chromosome and mortality after coronary angiography.
Weyrich M, Zewinger S, Sarakpi T, ..., Speer T, Zeiher AM
Eur. Heart J. 46 (17) 1603-1616 [2025-05-02; online 2025-02-12]
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How to Train a Postprocessor for Tandem Mass Spectrometry Proteomics Database Search While Maintaining Control of the False Discovery Rate.
Freestone J, Käll L, Noble WS, Keich U
J. Proteome Res. 24 (5) 2266-2279 [2025-05-02; online 2025-03-31]
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Dual-Nuclide Biodistribution and Therapeutic Evaluation of a Novel Antibody-Based Radiopharmaceutical in Anaplastic Thyroid Cancer Xenografts.
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Cortical response to proprioceptive stimulation in primary orthostatic tremor - a magnetoencephalography study.
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Analysis of canine gene constraint identifies new variants for orofacial clefts and stature.
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Genome Res 35 (5) 1080-1093 [2025-05-02; online 2025-05-02]
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Suppression of the Anti-inflammatory Cytokine Il-38 in Moderate to Severe COPD
Etienne S, Bandeira E, Lazarinis N, ..., Sköld M, Linden A
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Spatial metabolomics platform combining mass spectrometry imaging and in-depth chemical characterization with capillary electrophoresis.
Mavroudakis L, Golubova A, Lanekoff I
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IL-26 as a Potential Biomarker in Moderate to Severe COPD at a Tertiary Center
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Cryo-EM structure of the human monocarboxylate transporter 10.
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Autoantibodies towards HFE and SYT5 in anti-neutrophil cytoplasm antibody-associated vasculitis relapse.
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Using machine learning to investigate the influence of the prenatal chemical exposome on neurodevelopment of young children.
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Unraveling the influence of astrocytes on endothelial cell transcription: Towards understanding blood-brain barrier in vitro models' dynamics.
Zamproni LN, Gökçe B, Venckute Larsson J, ..., Porcionatto MA, Herland A
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The multifaceted role of post-translational modifications of LSD1 in cellular processes and disease pathogenesis.
Li Y, Wang B, Zheng Y, ..., Gao Y, Chen X
Genes Dis 12 (3) 101307 [2025-05-00; online 2024-04-15]
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The Role of Artificial Intelligence in the Evaluation of Prostate Pathology.
Egevad L, Camilloni A, Delahunt B, ..., Eklund M, Kartasalo K
Pathol Int 75 (5) 213-220 [2025-05-00; online 2025-04-14]
DDLS Fellow Kimmo Kartasalo
PubMed DOI Crossref
The Epstein-Barr virus deubiquitinase BPLF1 regulates stress-induced ribosome UFMylation and reticulophagy.
Liu J, Nagy N, Ayala-Torres C, ..., Larsson O, Masucci MG
Autophagy 21 (5) 996-1018 [2025-05-00; online 2025-01-22]
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TOR1AIP2 as a candidate gene for dystonia-hemichorea/hemiballism.
Kafantari E, Hernandez VJ, Necpál J, ..., Schwartz TU, Puschmann A
Parkinsonism Relat Disord 134 (-) 107781 [2025-05-00; online 2025-03-11]
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Sustained Release of Proteins Using Region‐Specific Tunable Degradability in Hydrogels through 3D Photopatterning and Complimentary Labile Bond Chemistry
Kivijärvi T, Cerrato CP, Kohlan TB, ..., Arsenian‐Henriksson M, Finne‐Wistrand A
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Structural and antigen-binding surface definition of an anti-CD93 monoclonal antibody for the treatment of degenerative vascular eye diseases.
Raucci L, Perrone CD, Barbera S, ..., Galvagni F, Orlandini M
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Spatial miRNomics: towards the integration of microRNAs in spatial biology.
Robles-Remacho A, Nilsson M
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Single-cell sequencing reveals shared clonal signatures in nonmalignant B and tumor cells in T-prolymphocytic leukemia.
Hesselager C, Thörn I, Marincevic M, ..., Baliakas P, Amini RM
Blood Neoplasia 2 (2) 100076 [2025-05-00; online 2025-02-16]
PubMed DOI Crossref
Reply to the Letter to the Editor regarding "Early detection of pancreatic cancer: Study design and analytical considerations in biomarker discovery and early phase validation studies".
Mahoney DM, Smith LM, Wang QL, ..., Oberg AL, PCDC Biostatistics Subcommittee
Pancreatology 25 (3) 487-488 [2025-05-00; online 2025-05-10]
DDLS Fellow Qiaoli Wang
PubMed DOI Crossref
Rare and low-frequency variants in families with otitis media.
Santos-Cortez RLP, Elling CL, Gomez HZ, ..., Hafrén L, Ryan AF
J. Mol. Med. 103 (5) 559-570 [2025-05-00; online 2025-04-04]
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Psychiatric genetics in the diverse landscape of Latin American populations.
Bruxel EM, Rovaris DL, Belangero SI, ..., Giusti-Rodríguez P, Montalvo-Ortiz JL
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Precision nutrition for cardiometabolic diseases.
Guasch-Ferré M, Wittenbecher C, Palmnäs M, ..., Sargent JL, Merino J
Nat. Med. 31 (5) 1444-1453 [2025-05-00; online 2025-04-30]
Clemens Wittenbecher DDLS Fellow
PubMed DOI Crossref
Plasticity of the mammalian integrated stress response.
Chen CW, Papadopoli D, Szkop KJ, ..., Topisirovic I, Hatzoglou M
Nature 641 (8065) 1319-1328 [2025-05-00; online 2025-03-26]
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Physical Color Calibration of Digital Pathology Scanners for Robust Artificial Intelligence-Assisted Cancer Diagnosis.
Ji X, Salmon R, Mulliqi N, ..., Eklund M, Kartasalo K
Mod. Pathol. 38 (5) 100715 [2025-05-00; online 2025-01-16]
DDLS Fellow Kimmo Kartasalo
PubMed DOI Crossref
Osteonecrosis not exclusively confined to the jawbones.
Stattin EL, Wikström J, Ojmaya W, Lerner UH
Br Dent J 238 (10) 750-751 [2025-05-00; online 2025-05-23]
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Multi-instance learning with attention mechanism for coronary artery stenosis detection on coronary computed tomography angiography.
Gupta V, Petursson P, Hilgendorf L, ..., Pirazzi C, Rawshani A
Eur Heart J Digit Health 6 (3) 382-391 [2025-05-00; online 2025-04-01]
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MEA-seqX: High-Resolution Profiling of Large-Scale Electrophysiological and Transcriptional Network Dynamics.
Emery BA, Hu X, Klütsch D, ..., Kempermann G, Amin H
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Large Inversions Shape Diversification and Genome Evolution in Common Quails.
Ravagni S, Montero-Mendieta S, Leonard JA, ..., Sanchez-Donoso I, Vilà C
Mol. Ecol. 34 (9) e17740 [2025-05-00; online 2025-04-04]
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Investigating the Microbiome in Relation to Mental Distress Across Two Points During Pregnancy: Data From U.S. and Swedish Cohorts.
Kimmel M, Tong B, Devall AE, ..., Skalkidou A, Hugerth LW
Biol Psychiatry Glob Open Sci 5 (3) 100453 [2025-05-00; online 2025-01-30]
DDLS Fellow Luisa Hugerth
PubMed DOI Crossref
In Vitro Elimination of Highly Multidrug-Resistant Bacteria by the Lactic Acid Bacterial Drug Candidate ILP100.
Lofton-Tomenius H, Pang Y, Pallin A, ..., Roos S, Phillipson M
Infect Dis Ther 14 (5) 1119-1131 [2025-05-00; online 2025-03-31]
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Identification and interpretation of risk factors for Charcot foot. Reply to Milbourn VEL, Bus SA, Game F, van Netten JJ [letter].
Tsatsaris G, Ekberg NR, Fall T, Catrina SB
Diabetologia 68 (5) 1078-1079 [2025-05-00; online 2025-02-20]
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High-throughput biodiversity surveying sheds new light on the brightest of insect taxa.
Iwaszkiewicz-Eggebrecht E, Goodsell RM, Bengsson BÅ, ..., Roslin T, Ronquist F
Proc. Biol. Sci. 292 (2046) 20242974 [2025-05-00; online 2025-05-14]
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From transdiagnostic risk prediction to personalized prevention in psychiatry: Designing studies to determine heterogeneity of treatment effects.
Cervenka S, Sundström J
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Error Reduction in Leukemia Machine Learning Classification With Conformal Prediction.
Lysenkova Wiklander M, Zachariah D, Krali O, Nordlund J
JCO Clin Cancer Inform 9 (-) e2400324 [2025-05-00; online 2025-05-28]
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Dairy intake, plasma metabolome, and risk of type 2 diabetes in a population-based cohort.
Zhang S, Janzi S, Du Y, ..., Borné Y, Sonestedt E
Am. J. Clin. Nutr. 121 (5) 1137-1148 [2025-05-00; online 2025-04-03]
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Cell-intrinsic metabolic phenotypes identified in patients with glioblastoma, using mass spectrometry imaging of 13C-labelled glucose metabolism.
Tsyben A, Dannhorn A, Hamm G, ..., Mair R, Brindle KM
Nat Metab 7 (5) 928-939 [2025-05-00; online 2025-05-19]
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Advancing transdisciplinary research on Madagascar's grassy biomes to support resilience in ecosystems and livelihoods
Phelps LN, Razanatsoa E, Davis DS, ..., Vorontsova MS, Lehmann CER
Ecological Monographs 95 (2) - [2025-05-00; online 2025-07-15]
DDLS Fellow Tobias Andermann
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Small molecule bioactivity benchmarks are often well-predicted by counting cells
Seal S, Dee W, Shah A, ..., Bender A, Carpenter AE
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Maternal uniparental disomy of chromosome 7: how chromosome 7-encoded imprinted genes contribute to the Silver-Russell phenotype.
Begemann M, Lengyel A, Pinti E, ..., Kraft F, Eggermann T
Clin Epigenetics 17 (1) 70 [2025-04-30; online 2025-04-30]
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High Content Imaging Applications of Advanced and Translational Disease Models in Drug Discovery and Development
Cui W, Haffa M, Massai F, ..., Axelsson H, Seashore-Ludlow B
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Engineering cardiolipin binding to an artificial membrane protein reveals determinants for lipid-mediated stabilization.
Abramsson ML, Corey RA, Skerle JL, ..., Stansfeld PJ, Landreh M
Elife 14 (-) - [2025-04-30; online 2025-04-30]
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Engineering cardiolipin binding to an artificial membrane protein reveals determinants for lipid-mediated stabilization
Abramsson ML, Corey RA, Skerle JL, ..., Stansfeld PJ, Landreh M
Elife 14 (-) - [2025-04-30; online 2025-04-30]
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Author response: Engineering cardiolipin binding to an artificial membrane protein reveals determinants for lipid-mediated stabilization
Abramsson ML, Corey RA, Skerle JL, ..., Stansfeld PJ, Landreh M
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The overlooked trio: sleep duration, sampling time and physical exercise alter levels of olink-assessed blood biomarkers of cardiovascular risk.
Brandão LEM, Zhang L, Grip A, ..., Benedict C, Cedernaes J
Biomark Res 13 (1) 67 [2025-04-29; online 2025-04-29]
Daniel Espes SciLifeLab Fellow
PubMed DOI Crossref
Structure and Inhibition of the Human Na+/H+ Exchanger SLC9B2.
Jung S, Kokane S, Li H, ..., Nomura N, Drew D
Int J Mol Sci 26 (9) - [2025-04-29; online 2025-04-29]
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Met-ID: An Open-Source Software for Comprehensive Annotation of Multiple On-Tissue Chemical Modifications in MALDI-MSI.
Bjärterot P, Nilsson A, Shariatgorji R, ..., Käll L, Andrén PE
Anal. Chem. 97 (16) 9033-9041 [2025-04-29; online 2025-04-20]
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GenePioneer: a comprehensive Python package for identification of essential genes and modules in cancer.
Haerianardakani A, Taheri G
Bioinform Adv 5 (1) vbaf094 [2025-04-29; online 2025-04-29]
DDLS Fellow Golnaz Taheri
PubMed DOI Crossref
Quantifying Acyl Chain Interdigitation in Simulated Bilayers via Direct Transbilayer Interactions.
Chaisson EH, Heberle FA, Doktorova M
J Chem Inf Model 65 (8) 3879-3885 [2025-04-28; online 2025-04-16]
DDLS Fellow Milka Doktorova
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Mitochondrial Dysfunction Induces Hepatic Lipid Accumulation and Inflammatory Responses in mtDNA Mutator Mice
Ross JM, Kim A, Berthod K, ..., Olson L, Coppotelli G
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Low anabolic independence emerges when cultivating more than three bacterial species together
Pacheco-Valenciana A, Tausch A, Veseli I, ..., Andersson AF, Garcia SL
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Sarahi Garcia SciLifeLab Fellow
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Multiplexed Deep Visual Proteomics Unveils Spatial Heterogeneity and Rare Endocrine States in Human Adult Pancreatic Islets
Mardamshina M, Dorka N, Thielert M, ..., Mann M, Lundberg E
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Dear Diary: A Randomized Controlled Trial of Generative AI Coding Tools in the Workplace
Butler J, Suh J, Haniyur S, Hadley C
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The time dimension matters: Improving mode of action classification with live-cell imaging
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Local, calcium- and reward-based synaptic learning rule that enhances dendritic nonlinearities can solve the nonlinear feature binding problem
Khodadadi Z, Trpevski D, Lindroos R, Hellgren Kotaleski J
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Conformal prediction enables disease course prediction and allows individualized diagnostic uncertainty in multiple sclerosis.
Sreenivasan AP, Vaivade A, Noui Y, ..., Spjuth O, Kultima K
NPJ Digit Med 8 (1) 224 [2025-04-24; online 2025-04-24]
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Author response: Local, calcium- and reward-based synaptic learning rule that enhances dendritic nonlinearities can solve the nonlinear feature binding problem
Khodadadi Z, Trpevski D, Lindroos R, Hellgren Kotaleski J
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Astrocytic lipid droplets contain MHCII and may act as cogs in the antigen presentation machinery.
Beretta C, Dakhel A, Eltom K, ..., Michno WP, Erlandsson A
J Neuroinflammation 22 (1) 117 [2025-04-24; online 2025-04-24]
SciLifeLab Fellow Wojciech Michno
PubMed DOI Crossref
A CRISPR homing screen finds a chloroquine resistance transporter-like protein of the Plasmodium oocyst essential for mosquito transmission of malaria.
Balakrishnan A, Hunziker M, Tiwary P, ..., Drew D, Billker O
Nat Commun 16 (1) 3895 [2025-04-24; online 2025-04-24]
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The evaluation of biogenic silica in brackish and freshwater strains reveals links between phylogeny and silica accumulation in picocyanobacteria.
Aguilera A, Lundin D, Charalampous E, ..., Farnelid H, Pinhassi J
Applied and environmental microbiology 91 (4) e0252724 [2025-04-23; online 2025-03-27]
PubMed DOI Crossref
Simultaneous polyclonal antibody sequencing and epitope mapping by cryo electron microscopy and mass spectrometry.
Schulte D, Šiborová M, Käll L, Snijder J
Elife 14 (-) - [2025-04-23; online 2025-04-23]
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Simultaneous polyclonal antibody sequencing and epitope mapping by cryo electron microscopy and mass spectrometry
Schulte D, Šiborová M, Käll L, Snijder J
Elife 14 (-) - [2025-04-23; online 2025-04-23]
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Mechanisms of chemotherapy failure in refractory/relapsed acute myeloid leukemia: the role of cytarabine resistance and mitochondrial metabolism.
Yeon Chae S, Jang SY, Kim J, ..., Kim JS, Kim HI
Cell Death Dis 16 (1) 331 [2025-04-23; online 2025-04-23]
PubMed DOI Crossref
A rich conformational palette underlies human CaV2.1-channel availability.
Wang K, Nilsson M, Angelini M, ..., Elinder F, Pantazis A
Nat Commun 16 (1) 3815 [2025-04-23; online 2025-04-23]
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Sex differences in DNMT3A-mutant clonal hematopoiesis and the effects of estrogen.
Stomper J, Niroula A, Belizaire R, ..., Bandaru TS, Ebert BL
Cell Reports 44 (4) 115494 [2025-04-22; online 2025-04-02]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
Omics Approach for Personalised Prevention of Type 2 Diabetes Mellitus for African and European Populations (OPTIMA): a protocol paper.
Goedecke JH, Danquah I, Abidha CA, ..., Landberg R, Olsson T
BMJ Open 15 (4) e099108 [2025-04-22; online 2025-04-22]
Clemens Wittenbecher DDLS Fellow
PubMed DOI Crossref
Mapping effective microRNA pairing beyond the seed using abasic modifications.
Kosek DM, Petzold K, Andersson ER
Nucleic Acids Res. 53 (8) - [2025-04-22; online 2025-04-29]
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Genetics of canine cancer: a guide for the veterinary oncologist
Arendt ML, van der Heiden AD, Pensch R, Lindblad-Toh K
Vet. Oncol. 2 (1) - [2025-04-22; online 2025-04-22]
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Discovery of an ene-reductase initiating resveratrol catabolism in gut microbiota and its application in disease treatment.
Dong Z, Yu P, Li J, ..., Gu Y, Yang Y
Cell Reports 44 (4) 115517 [2025-04-22; online 2025-04-04]
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Abstract 5300: Spatially resolved integrated omics profiling for ADC targets in urothelial carcinoma
Panshikar P, O´Roberts E, Krantz D, ..., Ullén A, Stadler C
Cancer Res. 85 (8_Supplement_1) 5300-5300 [2025-04-21; online 2025-04-21]
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Abstract 176: Simultaneous spatial characterisation of copy number change and immune cell profiling using DNA FISH and multiplexed immunofluorescence
O'Roberts EM, Panshikar P, Li-Wang X, ..., Bienko M, Stadler C
Cancer Res. 85 (8_Supplement_1) 176-176 [2025-04-21; online 2025-04-21]
Magda Bienko SciLifeLab Fellow
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Nanobinders for Synaptotagmin 1 enable the analysis of synaptic vesicle dynamics in rodent and human models
Goel R, Jevdokimenko K, Rehm R, ..., Rizzoli SO, Fornasiero EF
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Ilaria Testa SciLifeLab Fellow
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A co-speciation dilemma and a lifestyle transition with genomic consequences in Wolbachia of Neotropical Drosophila
Papachristos K, Miller WJ, Klasson L
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PubMed DOI Crossref
Targeted inhibition of WIP1 and histone H3K27 demethylase activity synergistically suppresses neuroblastoma growth.
Treis D, Lundberg KI, Bell N, ..., Johnsen JI, Wickström M
Cell Death Dis 16 (1) 318 [2025-04-19; online 2025-04-19]
PubMed DOI Crossref
Dynamically chiral phosphonic acid-type metallo-β-lactamase inhibitors.
Gulyás KV, Zhou L, Salamonsen D, ..., Zhu W, Erdélyi M
Commun Chem 8 (1) 119 [2025-04-19; online 2025-04-19]
PubMed DOI Crossref
Functional relevance of CASP16 nucleic acid predictions as evaluated by structure providers.
Kretsch RC, Albrecht R, Andersen ES, ..., Moult J, Kryshtafovych A
bioRxiv - (-) - [2025-04-18; online 2025-04-18]
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Genomic studies in Linum shed light on the evolution of the distyly supergene and the molecular basis of convergent floral evolution
Zervakis PI, Postel Z, Losvik A, ..., Churcher A, Slotte T
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SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Functionalized gold nanoflowers on carbon screen-printed electrodes: an electrochemical platform for biosensing hemagglutinin protein of influenza A H1N1 virus.
Torres-Méndez CE, Nandi S, Martinovic K, ..., Mestres G, Kamali-Moghaddam M
Beilstein J Nanotechnol 16 (-) 540-550 [2025-04-16; online 2025-04-16]
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AlphaFold3 at CASP16
Elofsson A
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PubMed DOI Crossref
Integrated computational and biosensor-based strategies for the discovery of allosteric SMYD3 ligands using diperodon as a starting point.
FitzGerald EA, Rachman MM, Cederfelt D, ..., Koehler K, Danielson UH
Bioorg. Med. Chem. 121 (-) 118134 [2025-04-15; online 2025-02-25]
DOI Crossref
In Vitro Evaluation of Flame-Made Calcium Phosphate Nanoparticles for Antigen Delivery and Immunostimulation
Maheshwari A, Dookie R, Gaytán MO, Henriques-Normark B, Sotiriou GA
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Phenotypic Antibiotic Susceptibility Testing at the limit of one bacterial cell
Johansson L, Ahmad I, Larsson J, ..., Fange D, Elf J
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PubMed DOI Crossref
Cytoskeletal alterations in neuronal cells implicate Toxoplasma gondii secretory machinery and host microRNA-containing extracellular vesicles.
Mazza T, Aslanzadeh M, Berentsen L, ..., Friedländer MR, Barragan A
Sci Rep 15 (1) 12606 [2025-04-12; online 2025-04-12]
Marc Friedländer SciLifeLab Fellow
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A Systematic Host-Centric Approach to Identifying Repurposed Drugs for Viral Infections
Tampere M, Asp E, Rietdijk J, ..., Seashore-Ludlow B, Östling P
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Discovering cryptic pocket opening and binding of a stimulant derivative in a vestibular site of the 5-HT3A receptor.
Haloi N, Karlsson E, Delarue M, Howard RJ, Lindahl E
Sci Adv 11 (15) eadr0797 [2025-04-11; online 2025-04-11]
PubMed DOI Crossref
Antibacterial compounds against non-growing and intracellular bacteria.
Kaldalu N, Bērziņš N, Berglund Fick S, ..., Hauryliuk V, Tenson T
NPJ Antimicrob Resist 3 (1) 25 [2025-04-11; online 2025-04-11]
PubMed DOI Crossref
Nuclear AGO2 supports influenza A virus replication through type-I interferon regulation.
Huang HC, Fong M, Nowak I, ..., Angeletti D, Sarshad AA
Nucleic Acids Res. 53 (7) - [2025-04-10; online 2025-04-12]
PubMed DOI Crossref
Genome-wide analyses identify 30 loci associated with obsessive-compulsive disorder.
Strom NI, Gerring ZF, Galimberti M, ..., Derks EM, Mattheisen M
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Cotranslational membrane insertion of the voltage-sensitive K+ channel KvAP.
Westerfield JM, Kozojedová P, Juli C, Metola A, von Heijne G
Proc. Natl. Acad. Sci. U.S.A. 122 (14) e2412492122 [2025-04-08; online 2025-03-31]
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Towards personalized prostate cancer treatment with docetaxel in indonesia: a pharmacogenomics perspective
Malau J, Rohmah S, Meilani ND, ..., Raekiansyah M, Manalu RT
Egypt J Med Hum Genet 26 (1) - [2025-04-07; online 2025-04-07]
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Revisiting the African mtDNA Landscape: A Continental Update from Complete Mitochondrial Genomes
Lankheet I, Chowdhury A, Tellgren-Roth C, ..., Malmström H, Schlebusch CM
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G-quadruplex profiling in complex tissues using single-cell CUT&Tag
Lyu J, Hetey S, Castelo-Branco G, Bartosovic M, Elsässer SJ
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SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Vaccine-enhanced competition permits rational bacterial strain replacement in the gut.
Lentsch V, Woller A, Rocker A, ..., Diard M, Slack E
Science (New York, N.Y.) 388 (6742) 74-81 [2025-04-04; online 2025-04-03]
PubMed DOI Crossref
Long-term gamma-aminobutyric acid (GABA) treatment fails to regain beta-cell function in longstanding type 1 diabetes in a randomized trial.
Hill H, Lundkvist P, Tsatsaris G, ..., Espes D, Carlsson PO
Sci Rep 15 (1) 11530 [2025-04-04; online 2025-04-04]
Daniel Espes SciLifeLab Fellow
DOI Crossref
Revealing molecular determinants of ligand efficacy and affinity at the D 2 dopamine receptor through molecular dynamics simulations
Chen Y, Kahlous NA, Saarinen M, ..., Delemotte L, Carlsson J
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Jens Carlsson Lucie Delemotte SciLifeLab Fellow
DOI Crossref
Pairwise Attention: Leveraging Mass Differences to Enhance De Novo Sequencing of Mass Spectra
Lapin J, Nilsson A, Wilhelm M, Käll L
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Lucie Delemotte SciLifeLab Fellow
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Meth EMS, Nôga DA, Dubol M, ..., Sundström-Poromaa I, Benedict C
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Journal of Molecular Structure 1326 (-) 141110 [2025-04-00; online 2025-04-00]
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Nat Comput Sci 5 (4) 301-312 [2025-04-00; online 2025-03-13]
Andreas Luttens DDLS Fellow Jens Carlsson SciLifeLab Fellow
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Probiotics Antimicrob Proteins 17 (2) 918-936 [2025-04-00; online 2024-11-18]
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Plasma H3Cit-DNA Discriminates Between Cancer and Inflammation in a Cohort of Patients with Unspecific Cancer Symptoms.
Wannberg F, Hjalmar V, Ng H, ..., Rosell A, Thålin C
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Lee S, Arefaine B, Begum N, ..., Shoaie S, Patel VC
J Hepatol 82 (4) 622-633 [2025-04-00; online 2024-10-22]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
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Optimizing Xenium In Situ data utility by quality assessment and best-practice analysis workflows.
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Nat. Methods 22 (4) 813-823 [2025-04-00; online 2025-03-13]
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O-10.01 CD44v6-specific CAR-NK cells: a novel approach to precision medicine in bladder cancer
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MIA40 suppresses cell death induced by apoptosis-inducing factor 1.
Mussulini BHM, Maruszczak KK, Draczkowski P, ..., Wasilewski M, Chacinska A
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Host Plasma Microenvironment in Immunometabolically Impaired HIV Infection Leads to Dysregulated Monocyte Function and Synaptic Transmission Ex Vivo.
Mikaeloff F, Gelpi M, Escós A, ..., Nielsen SD, Neogi U
Adv Sci (Weinh) 12 (16) e2416453 [2025-04-00; online 2025-02-27]
Adil Mardinoglu SciLifeLab Fellow
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Formulation and Characterization of Novel Ionizable and Cationic Lipid Nanoparticles for the Delivery of Splice-Switching Oligonucleotides.
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Flow cytometry reveals constant lymphocyte proportions after long-term cryopreservation of whole blood in TransFix® cell stabilization reagent.
Faresjö M, Johansson J, Islander U, Tompa A
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Fibromyalgia patients have altered lipid concentrations associated with disease symptom severity and anti-satellite glial cell IgG antibodies.
Jakobsson JE, Menezes J, Krock E, ..., Svensson CI, Kultima K
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Enabling global image data sharing in the life sciences.
Bajcsy P, Bhattiprolu S, Börner K, ..., Taylor A, Keppler A
Nat. Methods 22 (4) 672-676 [2025-04-00; online 2025-03-28]
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Correction: Umbilical cord-derived mesenchymal stromal cells preserve endogenous insulin production in type 1 diabetes: a Phase I/II randomised double-blind placebo-controlled trial.
Carlsson PO, Espes D, Sisay S, ..., Smith CIE, Svahn MG
Diabetologia 68 (4) 900-901 [2025-04-00; online 2025-02-25]
Daniel Espes SciLifeLab Fellow
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Benchmarking of Quantitative Proteomics Workflows for Limited Proteolysis Mass Spectrometry.
Koudelka T, Bassot C, Piazza I
Mol. Cell Proteomics 24 (4) 100945 [2025-04-00; online 2025-03-13]
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A burden of rare copy number variants in obsessive-compulsive disorder.
Halvorsen MW, de Schipper E, Bäckman J, ..., Mataix-Cols D, Crowley JJ
Mol. Psychiatry 30 (4) 1510-1517 [2025-04-00; online 2024-10-27]
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Evolutionary rescue of spherical mreB deletion mutants of the rod-shape bacterium Pseudomonas fluorescens SBW25.
Yulo PRJ, Desprat N, Gerth ML, ..., Rainey PB, Hendrickson HL
Elife 13 (-) - [2025-03-31; online 2025-03-31]
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Evolutionary rescue of spherical mreB deletion mutants of the rod-shape bacterium Pseudomonas fluorescens SBW25
Yulo PRJ, Desprat N, Gerth ML, ..., Rainey PB, Hendrickson HL
Elife 13 (-) - [2025-03-31; online 2025-03-31]
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Wang X, Fontsere C, Caballero XA, ..., Pacheco C, Morales HE
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Solution architecture of G3BP1 reveals pH-dependent conformational switching underlying liquid-liquid phase separation
Han X, Sun R, Graewert MA, ..., Svergun D, Achour A
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Predicting retention on immobilized artificial membrane chromatography: Lipophilicity-based versus lipophilicity-independent models.
Vallianatou T, Tsopelas F, Tsantili-Kakoulidou A
J Chromatogr A 1745 (-) 465752 [2025-03-29; online 2025-02-04]
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The DNA methylation landscape of primary triple-negative breast cancer.
Aine M, Nacer DF, Arbajian E, ..., Borg Å, Staaf J
Nat Commun 16 (1) 3041 [2025-03-28; online 2025-03-28]
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PIP2-mediated oligomerization of the endosomal sodium/proton exchanger NHE9.
Kokane S, Gulati A, Meier PF, ..., Fuster D, Drew D
Nat Commun 16 (1) 3055 [2025-03-28; online 2025-03-28]
Lucie Delemotte SciLifeLab Fellow
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Development of DARPin T cell engagers for specific targeting of tumor-associated HLA/peptide complexes
Venetz-Arenas N, Schulte T, Müller S, ..., Walser M, Achour A
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A Multi-Omic Phenobank Reveals Axes of Glioblastoma Growth, Invasion, and Therapeutic Vulnerability
Krona C, Kundu S, Rosen E, ..., Mangukiya HB, Nelander S
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Measures of Homozygosity and Relationship to Genetic Diversity in the Bearded Collie Breed.
Belanger JM, Gershony LC, Bell JS, ..., Famula TR, Oberbauer AM
Genes (Basel) 16 (4) - [2025-03-27; online 2025-03-27]
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Synthesis and preclinical evaluation of gastrin releasing peptide receptor antagonist [18F]MeTz-PEG2-RM26 for positron emission tomography.
Kanellopoulos P, Lundmark F, Abouzayed A, ..., Eriksson J, Orlova A
EJNMMI Radiopharm Chem 10 (1) 14 [2025-03-26; online 2025-03-26]
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Engineering cardiolipin binding to an artificial membrane protein reveals determinants for lipid-mediated stabilization
Abramsson ML, Corey RA, Škerle J, ..., Stansfeld PJ, Landreh M
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Author response: Engineering cardiolipin binding to an artificial membrane protein reveals determinants for lipid-mediated stabilization
Abramsson ML, Corey RA, Škerle J, ..., Stansfeld PJ, Landreh M
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The ecological success of freshwater microorganisms is mediated by streamlining and biotic interactions
Rodríguez-Gijón A, Pacheco-Valenciana A, Milke F, ..., Rodriguez-R. LM, Garcia SL
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Sarahi Garcia SciLifeLab Fellow
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Identification of a SNAI1 enhancer RNA that drives cancer cell plasticity.
Fan C, Wang Q, Krijger PHL, ..., de Laat W, Ten Dijke P
Nat Commun 16 (1) 2890 [2025-03-25; online 2025-03-25]
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Ectopic germinal centers in the nasal turbinates contribute to B cell immunity to intranasal viral infection and vaccination.
Gailleton R, Mathew NR, Reusch L, ..., Bemark M, Angeletti D
Proc. Natl. Acad. Sci. U.S.A. 122 (12) e2421724122 [2025-03-25; online 2025-03-20]
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Hennig K, Malheiro A, Gomes ER, Corbat AA
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Combination treatment with anti-RANKL and antibiotics for preventing joint destruction in septic arthritis.
Hu Z, Deshmukh M, Jarneborn A, ..., Mohammad M, Jin T
JCI Insight 10 (6) - [2025-03-24; online 2025-03-24]
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Clinical utility of the FilmArray® meningitis/encephalitis panel in children with suspected central nervous system infection in a low-resource setting - a prospective study in Southwestern Uganda.
Rasti R, Kumbakumba E, Nanjebe D, ..., Alfvén T, Gaudenzi G
BMC Infect Dis 25 (1) 396 [2025-03-22; online 2025-03-22]
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Arnold H, Panara V, Allalou A, Koltowska K
STAR Protoc 6 (1) 103632 [2025-03-21; online 2025-02-08]
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Author Correction: Integrative spatial and genomic analysis of tumor heterogeneity with Tumoroscope.
Shafighi S, Geras A, Jurzysta B, ..., Lagergren J, Szczurek E
Nat Commun 16 (1) 2801 [2025-03-21; online 2025-03-21]
Camilla Engblom SciLifeLab Fellow
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Schlesinger D, Dirks C, Navarro C, ..., Martinez TF, Elsässer SJ
iScience 28 (3) 111884 [2025-03-21; online 2025-01-23]
SciLifeLab Fellow Simon Elsässer
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Unlocking protein networks with Predictomes: The SPOC advantage.
Elofsson A
Mol. Cell 85 (6) 1050-1051 [2025-03-20; online 2025-03-22]
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Transcriptional architecture and Pol II regulation at promoters, enhancers, and enhancer clusters in Canis lupus familiaris
Himanen SV, Rabenius A, Aktay S, Tekoniemi J, Vihervaara A
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Anniina Vihervaara SciLifeLab Fellow
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Seal milk oligosaccharides rival human milk complexity and exhibit functional dynamics during lactation
Jin C, Lundstrøm J, Cori CR, ..., Khoo KH, Bojar D
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DDLS Fellow Johan Bengtsson-Palme
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Pathway activation model for personalized prediction of drug synergy
Trac QT, Huang Y, Erkers T, ..., Pawitan Y, Vu TN
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Lab-in-a-Fiber detection and capture of cells.
Varela JC, Harish AV, Maniewski P, ..., Russom A, Laurell F
Sci Rep 15 (1) 9694 [2025-03-20; online 2025-03-20]
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Comparative Analysis of Salivary and Serum Inflammatory Mediator Profiles in Patients With Rheumatoid Arthritis and Periodontitis.
Fei C, Eriksson K, Fei G, ..., Jansson L, Yucel-Lindberg T
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Author response: Pathway activation model for personalized prediction of drug synergy
Trac QT, Huang Y, Erkers T, ..., Pawitan Y, Vu TN
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Survival and adaptative strategies of Enterotoxigenic E. coli (ETEC) to the freshwater environment.
Sjöling Å, Ashokkumar E, Bjurnemark C, ..., Zhu B, Joffré E
Res Sq - (-) - [2025-03-19; online 2025-03-19]
Astrid von Mentzer DDLS Fellow
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Senataxin prevents replicative stress induced by the Myc oncogene.
Sberna S, Filipuzzi M, Bianchi N, ..., Curti L, Campaner S
Cell Death Dis 16 (1) 187 [2025-03-19; online 2025-03-19]
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Early gonadotoxic effects of cyclophosphamide on the prepubertal testis and the feasibility of reducing toxicity through combined antioxidant therapy
Eskafinoghani A, Reyes Palomares A, Hao X, ..., Lundberg A, Rodriguez-Walberg KA
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Arian Lundberg DDLS Fellow
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Disinfecting eukaryotic reference genomes to improve taxonomic inference from ancient environmental metagenomic data
Oskolkov N, Jin C, Clinton SL, ..., Heintzman PD, van der Valk T
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DDLS Fellow Tom van der Valk
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Characterizing the Sulfated and Glucuronidated (Poly)phenol Metabolome for Dietary Biomarker Discovery.
Tsiara I, Hervás Povo B, Alotaibi W, ..., Rodriguez-Mateos A, Globisch D
J Agric Food Chem 73 (11) 6702-6710 [2025-03-19; online 2025-03-02]
Daniel Globisch SciLifeLab Fellow
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Using feedback in pooled experiments augmented with imputation for high genotyping accuracy at reduced cost.
Clouard C, Nettelblad C
G3 15 (3) - [2025-03-18; online 2025-01-23]
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Simultaneous polyclonal antibody sequencing and epitope mapping by cryo electron microscopy and mass spectrometry – a perspective
Schulte D, Šiborová M, Käll L, Snijder J
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Schulte D, Šiborová M, Käll L, Snijder J
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A chromosome-level genome assembly of the European green toad (Bufotes viridis).
Rödin-Mörch P, Bunikis I, Choi E, ..., Proux-Wéra E, Höglund J
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ZEB1, a novel regulator of Junctional Adhesion Molecule A, impacts sensitivity of pancreatic cancer-associated fibroblasts to oncolytic reovirus
Dam N, Harryvan TJ, Dang H, ..., Hawinkels LJAC, Kemp V
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Immune-Coagulation Dynamics in Severe COVID-19: Insights from Autoantibody Profiling and Transcriptomics
Ambikan AT, Cederholm A, Rezene S, ..., Landegren N, Gupta S
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Human jejunal enteroids for studies of epithelial drug transport and metabolism
Ceylan M, Tzioufa F, Di Martino ML, ..., Hubert M, Artursson P
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Mikael Sellin SciLifeLab Fellow
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Enzyme-Embedded Biodegradable Plastic for Sustainable Applications: Advances, Challenges, and Perspectives.
Sun S
ACS Appl Bio Mater 8 (3) 1785-1796 [2025-03-17; online 2025-02-13]
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Disrupted bone microenvironment and immune recovery following total body irradiation in a murine model
Sághy T, Gupta P, Horkeby K, ..., Chagin AS, Engdahl C
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Targeting TUBG1 in RB1-negative tumors.
Lindström L, Zhou J, Villoutreix BO, ..., Olsson R, Alvarado-Kristensson M
FASEB J. 39 (5) e70431 [2025-03-15; online 2025-02-28]
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Markers of inflammation predicts long-term mortality in patients with acute coronary syndrome - a cohort study.
Odeberg J, Halling A, Ringborn M, ..., Odeberg H, Lindblad U
BMC Cardiovasc Disord 25 (1) 190 [2025-03-15; online 2025-03-15]
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Construction of an atlas of transcription factor binding during mouse development identifies popular regulatory regions.
Nordin A, Zambanini G, Enar Jonasson M, ..., Pagella P, Cantù C
Development 152 (6) - [2025-03-15; online 2025-03-24]
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Single-Photon Emission Computer Tomography Imaging of Prostate-Specific Membrane Antigen (PSMA) Expression in Prostate Cancer Patients Using a Novel Peptide-Based Probe [99mTc]Tc-BQ0413 with Picomolar Affinity to PSMA: A Phase I/II Clinical Study.
Medvedeva A, Chernov V, Larkina M, ..., Tolmachev V, Orlova A
ACS pharmacology & translational science 8 (3) 736-747 [2025-03-14; online 2025-02-21]
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Pharmacological inhibition of MutT homolog 1 (MTH1) in allergic airway inflammation as a novel treatment strategy.
Adler A, Bergwik J, Padra M, ..., Berglund UW, Egesten A
Respir. Res. 26 (1) 101 [2025-03-14; online 2025-03-14]
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LN’s -Test: A Principled Approach to -Testing in Single-Cell RNA Sequencing
Kviman O, Jun SH, Lagergren J
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Common connective tissue disorder and anti-cytokine autoantibodies are enriched in idiopathic multicentric castleman disease patients.
Feng A, Gonzalez MV, Kalaycioglu M, ..., Fajgenbaum DC, Utz PJ
Front Immunol 16 (-) 1528465 [2025-03-13; online 2025-03-13]
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Antisecretory factor as add-on treatment for newly diagnosed glioblastoma, IDH wildtype: study protocol for a randomized double-blind placebo-controlled trial.
Ehinger E, Darabi A, Visse E, ..., Bengzon J, Siesjö P
Trials 26 (1) 86 [2025-03-13; online 2025-03-13]
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Visible-Light-Switchable Molecular Glues for Reversible Control of Protein Function.
Zhang J, Herzog LK, Li S, Chen X, Wu YW
Chemistry 31 (15) e202403808 [2025-03-12; online 2025-01-21]
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The construction and validation of sub-phenotype-specific genetic risk scores in systemic lupus erythematosus: a novel approach using large-scale biobank data
Reid S, Sandling JK, Pucholt P, ..., Rönnblom L, Leonard D
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Multimodal brain cell atlas across the adult macaque lifespan
Zhang X, Lai G, Guo X, ..., Liu M, Esteban MA
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Cover Feature: Visible‐Light‐Switchable Molecular Glues for Reversible Control of Protein Function (Chem. Eur. J. 15/2025)
Zhang J, Herzog LK, Li S, Chen X, Wu Y
Chemistry 31 (15) - [2025-03-12; online 2025-03-12]
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An artificial motor protein that walks along a DNA track
Nilsson P, Robertson NO, Gustafsson N, ..., Linke H, Curmi PMG
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Trabecular-bone mimicking osteoconductive collagen scaffolds: an optimized 3D printing approach using freeform reversible embedding of suspended hydrogels.
Kontakis MG, Moulin M, Andersson B, ..., Kreuger J, Hailer NP
3D Print Med 11 (1) 11 [2025-03-11; online 2025-03-11]
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Longer scans boost prediction and cut costs in brain-wide association studies.
Ooi LQR, Orban C, Zhang S, ..., Yeo BTT, Alzheimer’s Disease Neuroimaging Initiative
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Abstract A017: Enhanced efficacy of anti-mesothelin CAR T cells in ovarian cancer through drug combinations: Impact of treatment kinetics, co-stimulatory domain, and donor variability
Pizarro LR, Poiret T, Gudoitytė G, ..., Magalhaes I, Erkers T
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Abstract 072: Plasma Metabolome Predicts Long-term Body Weight Gain and Type 2 Diabetes in Non-Obese Individuals
Wu Z, Liu B, Li J, ..., Hu Y, Sun Q
Circulation 151 (Suppl_1) - [2025-03-11; online 2025-03-11]
Clemens Wittenbecher DDLS Fellow
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A clinical prostate biopsy dataset with undetected cancer.
Chelebian E, Avenel C, Järemo H, ..., Wählby C, Bergh A
Sci Data 12 (1) 423 [2025-03-11; online 2025-03-11]
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cONcat: Computational reconstruction of concatenated fragments from long Oxford Nanopore reads
Petri AJ, Thi-Huyen Nguyen M, Rajwar A, Benson E, Sahlin K
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Erik Benson Kristoffer Sahlin SciLifeLab Fellow
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Towards high atom economy in whole-cell redox biocatalysis: up-scaling light-driven cyanobacterial ene-reductions in a flat panel photobioreactor.
Grimm HC, Erlsbacher P, Medipally H, ..., Paul CE, Kourist R
Green Chem. 27 (11) 2907-2920 [2025-03-10; online 2025-01-14]
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Next-level high-precision spatial omics enabled through parallel image acquisition and spatial similarity networking
Sharma VV, Toth G, Martinis R, ..., Kooij G, Lanekoff I
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Droplet microfluidics-based detection of very rare antibiotic-resistant subpopulation in clinical isolates of Escherichia coli from bloodstream infections
Agnihotri SN, Fatsis-Kavalopoulos N, Windhager J, Tenje M, Andersson DI
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The Federated European Genome-Phenome Archive as a global network for sharing human genomics data.
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Overview of Amidohydrolase: Structure, Activity, and Application in Pesticide Degradation
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MiR-186-5p inhibition restores synaptic transmission and neuronal network activity in a model of chronic stress.
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Cardio-metabolic-related plasma proteins reveal biological links between cardiovascular diseases and fragility fractures: a cohort and Mendelian randomisation investigation.
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The potential radiosensitization target PFKFB3 is related to response to radiotherapy in SweBCG91RT: a randomized clinical trial with long-term follow-up.
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Isolation of individual natural killer cells from deep, high-aspect ratio microwell arrays - an evaluative study
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Interpreting mammalian synonymous site conservation in light of the unwanted transcript hypothesis.
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Geographical variation in mitogenomes of the largetooth sawfish Pristis pristis : challenges and perspectives for conservation efforts
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CombiCTx: Screening diffusion gradients of anti-cancer drug combinations
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Calcium stabilization of a flexible N-terminal domain in a pentameric ligand-gated ion channel
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Associations of PFAS and OH-PCBs with risk of multiple sclerosis onset and disability worsening.
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Single-Cell Resolution of Cellular Damage Illuminates Disease Progression
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Single-cell omics-based characterization of human basophils reveals two transcriptionally distinct populations
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Functional proteoform group deconvolution reveals a broader spectrum of ibrutinib off-targets.
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Evaluating feature extraction in ovarian cancer cell line co-cultures using deep neural networks.
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DNA methylation patterns contribute to changes of cellular differentiation pathways in leukocytes with LOY from patients with Alzheimer´s disease.
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Genome-wide profiling of tRNA modifications reveal the presence of divergent signatures in Plasmodium falciparum
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Spatial mapping of DNA synthesis reveals dynamics and geometry of human replication nanostructures
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Retinal tau phosphorylation in Alzheimer’s disease: a mass spectrometry study
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Uncovering pre-cytokinetic block in cancer cells under shear stress using a disturbed flow-generating device.
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Characterization of a second class Ie ribonucleotide reductase.
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WNK1-dependent water influx is required for CD4+ T cell activation and T cell-dependent antibody responses.
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Sheathless elasto-inertial focusing of sub-25 nm particles in straight microchannels
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Erdinc Sezgin SciLifeLab Fellow
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Sequence-dependent scale for translocon-mediated insertion of interfacial helices in membranes.
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Functional-proteomics-based investigation of the cellular response to farnesyltransferase inhibition in lung cancer.
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Development of an In Situ G Protein-Coupled Receptor Fragment Molecule Screening Approach with High-Resolution Magic Angle Spinning Nuclear Magnetic Resonance.
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ACS chemical biology 20 (2) 401-411 [2025-02-21; online 2025-01-21]
Jens Carlsson SciLifeLab Fellow
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Biological signatures in the Alzheimer's continuum discriminate between diagnosis-related and -unrelated associations to ATN categories.
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Impact of Patient Online Record Access on Documentation: Scoping Review.
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First-in-human experience with GRPR antagonist [68Ga]Ga-NOTA-PEG2-RM26 in prostate and breast cancer patients using PET/CT.
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Data-driven resources and computational tools in non-model plant species.
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Applying 3D cultures and high-throughput technologies to study host-pathogen interactions.
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Front Immunol 16 (-) 1488699 [2025-02-20; online 2025-02-20]
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Genetic adaptation to amoxicillin in Escherichia coli: The limited role of dinB and katE.
Teichmann L, Wenne M, Luitwieler S, ..., Bengtsson-Palme J, Ter Kuile B
PLoS ONE 20 (2) e0312223 [2025-02-19; online 2025-02-19]
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A new understanding of Acanthamoeba castellanii: dispelling the role of bacterial pore-forming toxins in cyst formation and amoebicidal actions.
Yabrag A, Ullah N, Baryalai P, ..., Wai SN, Nadeem A
Cell death discovery 11 (1) 66 [2025-02-19; online 2025-02-19]
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Virtual fragment screening for DNA repair inhibitors in vast chemical space.
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Nat Commun 16 (1) 1741 [2025-02-18; online 2025-02-18]
Andreas Luttens DDLS Fellow Jens Carlsson SciLifeLab Fellow
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Integrative proteo-transcriptomic characterization of advanced fibrosis in chronic liver disease across etiologies.
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Adil Mardinoglu SciLifeLab Fellow
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Evolutionary rescue of spherical mreB deletion mutants of the rod-shape bacterium Pseudomonas fluorescens SBW25
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The cellular state space of AML unveils novel NPM1 subtypes with distinct clinical outcomes and immune evasion properties
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Synthesis and Characterization of Memantine-Loaded Niosomes for Enhanced Alzheimer's Disease Targeting.
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Maintenance of cell wall remodeling and vesicle production are connected in Mycobacterium tuberculosis.
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Maintenance of cell wall remodeling and vesicle production are connected in Mycobacterium tuberculosis
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Maternal concentrations of perfluoroalkyl sulfonates and alterations in white matter microstructure in the developing brains of young children.
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Towards an interpretable deep learning model of cancer.
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Rnalys: An Interactive Web Application for Transcriptomic Data Analysis and Visualization
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Repurposing doxycycline for the inhibition of monkeypox virus DNA polymerase: a comprehensive computational study.
Yousaf MA, Michel M, Khan AT, Noreen M, Bano S
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Functionally characterizing obesity-susceptibility genes using CRISPR/Cas9, in vivo imaging and deep learning.
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Sub-5 nm Silicon Nanopore Sensors: Scalable Fabrication via Self-Limiting Metal-Assisted Chemical Etching.
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Secure and federated quantitative trait loci mapping with privateQTL.
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Imaging Single Particle Profiler to Study Nanoscale Bioparticles Using Conventional Confocal Microscopy.
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Erdinc Sezgin SciLifeLab Fellow
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Dynamical organization of vimentin intermediate filaments in living cells revealed by MoNaLISA nanoscopy.
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Ilaria Testa SciLifeLab Fellow
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Cryo-EM ligand building using generative AI and molecular dynamics
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QuanFormer: A Transformer-Based Precise Peak Detection and Quantification Tool in LC-MS-Based Metabolomics.
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NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer's disease progression.
McManus RM, Komes MP, Griep A, ..., Latz E, Heneka MT
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Multi-tissue network analysis reveals the effect of JNK inhibition on dietary sucrose-induced metabolic dysfunction in rats.
Yang H, Zhang C, Kim W, ..., Turkez H, Mardinoglu A
Elife 13 (-) - [2025-02-11; online 2025-02-11]
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Multi-tissue network analysis reveals the effect of JNK inhibition on dietary sucrose-induced metabolic dysfunction in rats
Yang H, Zhang C, Kim W, ..., Turkez H, Mardinoglu A
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Spectral STED microscopy improves spectral sensitivity with polarity-sensitive probes and enables correlative measurements of membrane order and anomalous lipid diffusion
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High-content morphological profiling by Cell Painting in 3D spheroids
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Design, Synthesis, and Computational Evaluation of 3,4-Dihydroquinolin-2(1H)-One Analogues as Potential VEGFR2 Inhibitors in Glioblastoma Multiforme.
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Disparate and shared transcriptomic signatures associated with cortical atrophy in genetic behavioral variant frontotemporal degeneration.
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Accurate Protein Dynamic Conformational Ensembles: Combining AlphaFold, MD and Amide 15 N( 1 H) NMR Relaxation
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TGF-β induces cholesterol accumulation to regulate the secretion of tumor-derived extracellular vesicles.
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Population history and admixture of the Fulani people from the Sahel.
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Molecular basis of proton sensing by G protein-coupled receptors.
Howard MK, Hoppe N, Huang XP, ..., Coyote-Maestas W, Manglik A
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Lucie Delemotte SciLifeLab Fellow
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Analysis-ready VCF at Biobank scale using Zarr.
Czech E, Millar TR, Tyler W, ..., Hammerbacher J, Kelleher J
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Abnormalities in the functional activity of neural networks in a human iPSC model of Dravet syndrome
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Localized Nanopore Fabrication in Silicon Nitride Membranes by Femtosecond Laser Exposure and Subsequent Controlled Breakdown.
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Interpopulational Variation in Cyclotide Production in Heavy-Metal-Treated Pseudometallophyte (Viola tricolor L.).
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Identification of bioactive compounds with popular single-atom modifications: Comprehensive analysis and implications for compound design.
Feng B, Yu H, Dong X, Díaz-Holguín A, Hu H
Eur J Med Chem 283 (-) 117051 [2025-02-05; online 2024-11-13]
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Repeated positron emission tomography tracing neutrophil elastase in a porcine intensive-care sepsis model.
Wilske F, Eriksson O, Amini RM, ..., Castegren M, Antoni G
Intensive Care Med Exp 13 (1) 14 [2025-02-04; online 2025-02-04]
Olof Eriksson SciLifeLab Fellow
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P-type accumulation mode organic electrochemical transistor biosensor for xanthine detection in fish.
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Bianchi M, Kozyrev SV, Notarnicola A, ..., Lindblad-Toh K, with the DISSECT consortium and the ImmunoArray consortium
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International Journal of Gynecological Cancer 35 (2) 101462 [2025-02-00; online 2025-02-00]
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Towards improved functionality of mandibular reconstruction plates enabled by additively manufactured triply periodic minimal surface structures.
Alomar Z, Aramesh M, Thor A, ..., Concli F, D'Elia F
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Niklasson A, Finan PH, Smith MT, ..., Kosek E, Bjurström MF
Sleep Med Rev 79 (-) 102014 [2025-02-00; online 2024-10-05]
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The ZFHX3 GGC Repeat Expansion Underlying Spinocerebellar Ataxia Type 4 has a Common Ancestral Founder.
Chen Z, Alvarez Jerez P, Anderson C, ..., Ryten M, Houlden H
Mov Disord 40 (2) 363-369 [2025-02-00; online 2024-12-05]
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Rheumatoid Arthritis Related B-Cell Changes Are Found Already in the Risk-RA Phase.
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ProHap enables human proteomic database generation accounting for population diversity.
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Pain in idiopathic scoliosis not associated with known genetic variants for pain.
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Mechanisms of neutralization of toxSAS from toxin-antitoxin modules.
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Machine learning prediction of tau-PET in Alzheimer's disease using plasma, MRI, and clinical data.
Karlsson L, Vogel J, Arvidsson I, ..., Mattsson-Carlgren N, Hansson O
Alzheimers Dement 21 (2) e14600 [2025-02-00; online 2025-02-22]
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Let it shine: Autofluorescence of Papanicolaou-stain improves AI-based cytological oral cancer detection.
Lian W, Lindblad J, Runow Stark C, Hirsch JM, Sladoje N
Comput Biol Med 185 (-) 109498 [2025-02-00; online 2024-12-10]
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Genome-scale models in human metabologenomics.
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Efficiently accelerated bioimage analysis with NanoPyx, a Liquid Engine-powered Python framework.
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Nat. Methods 22 (2) 283-286 [2025-02-00; online 2025-01-02]
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Cerebrospinal fluid levels of NfM in relation to NfL and pNfH as prognostic markers in amyotrophic lateral sclerosis.
Olofsson J, Bergström S, Mravinacová S, ..., Nilsson P, Månberg A
Amyotroph Lateral Scler Frontotemporal Degener 26 (1-2) 113-123 [2025-02-00; online 2024-11-22]
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Cell Painting: a decade of discovery and innovation in cellular imaging.
Seal S, Trapotsi MA, Spjuth O, ..., Bender A, Carpenter AE
Nat. Methods 22 (2) 254-268 [2025-02-00; online 2024-12-05]
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Ceftazidime-avibactam tolerance and persistence among difficult-to-treat KPC-producing Klebsiella pneumoniae clinical isolates from bloodstream infections.
Abichabki N, Gaspar GG, Bortolato LR, ..., Darini ALC, Andrade LN
Eur. J. Clin. Microbiol. Infect. Dis. 44 (2) 343-353 [2025-02-00; online 2024-11-30]
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BPS2025 - Lipid and voltage regulation of Na+/H+ exchangers
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BPS2025 - Expansion of a chemically diverse fluoroprobe library to further utilize protein-adaptive differential scanning fluorimetry (paDSF)
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Biophysical Journal 124 (3) 390a [2025-02-00; online 2025-02-00]
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Biophysical Journal 124 (3) 123a [2025-02-00; online 2025-02-00]
Lucie Delemotte SciLifeLab Fellow
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Frampton DJA, Pipatpolkai T, Sridhar A, ..., Ottosson NE, Liin SI
Biophysical Journal 124 (3) 277a-278a [2025-02-00; online 2025-02-00]
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BPS2025 - Cardiotoxic effects of synthetic cannabinoid receptor agonists: Inhibition of hERG and Kv7.1/KCNE1 channels with proposed hERG binding site
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Biophysical Journal 124 (3) 345a [2025-02-00; online 2025-02-00]
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Author Correction: Large-scale benchmarking of circRNA detection tools reveals large differences in sensitivity but not in precision.
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Nat. Methods 22 (2) 448 [2025-02-00; online 2025-01-18]
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Author Correction: Cell Painting: a decade of discovery and innovation in cellular imaging.
Seal S, Trapotsi MA, Spjuth O, ..., Bender A, Carpenter AE
Nat. Methods 22 (2) 447 [2025-02-00; online 2024-12-13]
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Attitudes Toward Medical Assistance in Dying Among Swedish Palliative Care Professionals.
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Adaptation of Escherichia coli to ciprofloxacin and enrofloxacin: Differential proteomics of the SOS response and RecA-independent mechanisms.
Teichmann L, Pasman R, Luitwieler S, ..., Bengtsson-Palme J, Ter Kuile B
Int. J. Antimicrob. Agents 65 (2) 107420 [2025-02-00; online 2024-12-30]
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Acute Vestibular Syndrome Unmasking an RFC1-Spectrum Disorder.
Verrecchia L, Alm V, Thonberg H, ..., Nilsson D, Paucar M
Neurol Genet 11 (1) e200238 [2025-02-00; online 2025-01-16]
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A Microfluidic Platform for In Situ Studies of Bacteria Electroporation (Adv. Mater. Technol. 4/2025)
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A Heparan Sulfate Mimetic RAFT Copolymer Inhibits SARS-CoV-2 Infection and Ameliorates Viral-Induced Inflammation.
Ling J, Lundkvist Å, Guerrini M, ..., Li JP, Li J
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Trogocytosis of chimeric antigen receptors between T cells is regulated by their transmembrane domains.
Barbera S, Schuiling MJA, Sanjaya NA, ..., Essand M, Dimberg A
Sci Immunol 10 (103) eado2054 [2025-01-31; online 2025-01-31]
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Zika virus modulates human fibroblasts to enhance transmission success in a controlled lab-setting.
Mozūraitis R, Cirksena K, Raftari M, ..., Gerold G, Emami SN
Commun Biol 8 (1) 139 [2025-01-30; online 2025-01-30]
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Thermodynamic principles link in vitro transcription factor affinities to single-molecule chromatin states in cells.
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bioRxiv - (-) - [2025-01-30; online 2025-01-30]
Emil Marklund SciLifeLab Fellow
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Photosynthesis in Synechocystis sp. PCC 6803 is not optimally regulated under very high CO2.
Carrasquer-Alvarez E, Hoffmann UA, Geissler AS, ..., Hudson EP, Frigaard NU
Appl. Microbiol. Biotechnol. 109 (1) 33 [2025-01-30; online 2025-01-30]
Paul Hudson SciLifeLab Fellow
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Multi-tissue network analysis reveals the effect of JNK inhibition on dietary sucrose-induced metabolic dysfunction in rats
Yang H, Zhang C, Kim W, ..., Turkez H, Mardinoglu A
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Adil Mardinoglu SciLifeLab Fellow
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Diffusion Smart-seq3 of breast cancer spheroids to explore spatial tumor biology and test evolutionary principles of tumor heterogeneity.
Cougnoux A, Mahmoud L, Johnsson PA, ..., Sandberg R, Hausser J
Sci Rep 15 (1) 3811 [2025-01-30; online 2025-01-30]
Jean Hausser SciLifeLab Fellow
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Author response: Multi-tissue network analysis reveals the effect of JNK inhibition on dietary sucrose-induced metabolic dysfunction in rats
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Adil Mardinoglu SciLifeLab Fellow
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The genetic architecture of resistance to flubendiamide insecticide in Helicoverpa armigera (Hübner).
Amado D, Koch EL, Cordeiro EMG, ..., Jiggins CD, Omoto C
PLoS ONE 20 (1) e0318154 [2025-01-29; online 2025-01-29]
Gabriela Montejo-Kovacevich SciLifeLab Fellow
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Single-cell profiling reveals a novel RAB13+ endothelial subpopulation and profibrotic mesenchymal cells in the aged human bone marrow
Cenzano I, Cócera M, Lopez-Perez AR, ..., Gomez-Cabrero D, Prosper F
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Profetisk kamp för nationens pånyttfödelse
Poletti Lundström T
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From RIFT Audit to RIFT Turkey: Reappraising Appendicitis Risk Models for Global Relevance
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Impact Surgery 2 (1) 2-3 [2025-01-29; online 2025-01-29]
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Cellular and immune landscape of chronic liver diseases: insights from immunophenotyping.
Soleimani S, Albayrak O, Somay K, ..., Dayangac M, Zeybel M
Front Mol Biosci 11 (-) 1521811 [2025-01-29; online 2025-01-29]
Adil Mardinoglu SciLifeLab Fellow
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Evolution of complexity through regulatory variation at a single gene.
Ferreira MS
Proc. Natl. Acad. Sci. U.S.A. 122 (4) e2424050122 [2025-01-28; online 2025-01-21]
Mafalda Sousa Ferreira SciLifeLab Fellow
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Single-Virus Microscopy of Biochemical Events in Viral Entry.
Cervantes M, Mannsverk S, Hess T, ..., Villamil Giraldo A, Kasson PM
JACS Au 5 (1) 399-407 [2025-01-27; online 2024-12-31]
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Probing the Hidden Photoisomerization of a Symmetric Phosphaalkene Switch
Deka R, Steen JD, Hilbers MF, ..., Orthaber A, Crespi S
Angewandte Chemie 137 (5) - [2025-01-27; online 2024-12-13]
Ruisheng Xiong SciLifeLab Fellow
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Native Mass Spectrometry Captures the Conformational Plasticity of Proteins with Low-Complexity Domains.
Osterholz H, Stevens A, Abramsson ML, ..., Leppert A, Landreh M
JACS Au 5 (1) 281-290 [2025-01-27; online 2025-01-08]
SciLifeLab Fellow Sebastian Deindl
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Met-ID: An Open-Source Software for Comprehensive Annotation of Multiple On-Tissue Chemical Modifications in MALDI-MSI
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Lack of ST2 aggravates glioma invasiveness, vascular abnormality, and immune suppression.
Wicher G, Roy A, Vaccaro A, ..., Dimberg A, Forsberg-Nilsson K
Neurooncol Adv 7 (1) vdaf010 [2025-01-27; online 2025-01-27]
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A thermoplastic chip for 2D and 3D correlative assays combining screening and high-resolution imaging of immune cell responses.
van Ooijen H, Verron Q, Zhang H, ..., Sandström N, Önfelt B
Cell Rep Methods 5 (1) 100965 [2025-01-27; online 2025-01-17]
Patrick Sandoz SciLifeLab Fellow
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Germline-restricted chromosome of songbirds has different centromere compared to regular chromosomes
Rídl J, Dedukh D, Halenková Z, ..., Reif J, Reifová R
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FlashFold: a standalone command-line tool for accelerated protein structure and stoichiometry prediction
Saha CK, Roghanian M, Häussler S, Guy L
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Telomemore enables single-cell analysis of cell cycle and chromatin condensation.
Yakovenko I, Mihai IS, Selinger M, ..., Forsell M, Henriksson J
Nucleic Acids Res. 53 (3) - [2025-01-24; online 2025-01-29]
DDLS Fellow Laura Carroll
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Mettl15-Mettl17 modulates the transition from early to late pre-mitoribosome.
Zgadzay Y, Mirabello C, Wanes G, ..., Gahura O, Amunts A
bioRxiv - (-) - [2025-01-24; online 2025-01-24]
Alexey Amunts SciLifeLab Fellow
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Fegraeus K, Riihimäki M, Nordlund J, ..., Wernersson S, Raine A
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Multiomic profiling of metastatic potential in estrogen receptor-positive human epidermal growth factor-negative breast cancer
Mosquim S, Zamore M, Vallon-Christersson J, Rydén L, Levander F
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Characterizing and targeting glioblastoma neuron-tumor networks with retrograde tracing.
Tetzlaff SK, Reyhan E, Layer N, ..., Heiland DH, Venkataramani V
Cell 188 (2) 390-411.e36 [2025-01-23; online 2024-12-06]
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Proper 5'-3' cotranslational mRNA decay in yeast requires import of Xrn1 to the nucleus.
Jordán-Pla A, Zhang Y, García-Martínez J, ..., Pelechano V, Pérez-Ortín JE
PLoS ONE 20 (1) e0308195 [2025-01-22; online 2025-01-22]
SciLifeLab Fellow
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First-in-human, multicenter, open-label, phase I study of ATOR-1017 (evunzekibart), a 4-1BB antibody, in patients with advanced solid malignancies.
Carneiro A, Hahn A, Ellmark P, ..., Yachnin J, Ullenhag GJ
J Immunother Cancer 13 (1) - [2025-01-22; online 2025-01-22]
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Emotion regulation-based internet-delivered cognitive behavioural therapy for premenstrual dysphoric disorder: study protocol for a randomised controlled trial in Sweden.
Hoppe JM, Weise C, Kleinstaeuber M, ..., Andersson G, Buhrman M
BMJ Open 15 (1) e091649 [2025-01-22; online 2025-01-22]
Erika Comasco SciLifeLab Fellow
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All-Optical Strategies to Minimize Photo-Bleaching in Reversibly Switchable Fluorescent Proteins
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Ilaria Testa SciLifeLab Fellow
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Fluoroquinolone-specific resistance trajectories in E. coli and their dependence on the SOS-response.
Teichmann L, Luitwieler S, Bengtsson-Palme J, Ter Kuile B
BMC Microbiol. 25 (1) 37 [2025-01-21; online 2025-01-21]
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Comprehensive Approach for Sequential MALDI-MSI Analysis of Lipids, N-Glycans, and Peptides in Fresh-Frozen Rodent Brain Tissues.
Lee YR, Kaya I, Wik E, ..., Svenningsson P, Andrén PE
Anal. Chem. 97 (2) 1338-1346 [2025-01-21; online 2025-01-09]
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Visualization using NIPTviewer support the clinical interpretation of noninvasive prenatal testing results.
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BMC Med Genomics 18 (1) 15 [2025-01-20; online 2025-01-20]
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Oligodendroglia vulnerability in the human dorsal striatum in Parkinson’s disease
Barba-Reyes JM, Harder L, Salas SM, ..., Serrano-Pozo A, Muñoz-Manchado AB
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Single-Cell Morphological Profiling Reveals Insights into Programmed Cell Death
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Syngap1 promotes cognitive function through regulation of cortical sensorimotor dynamics.
Vaissiere T, Michaelson SD, Creson T, ..., Fontolan L, Rumbaugh G
Nat Commun 16 (1) 812 [2025-01-18; online 2025-01-18]
Daniel Fürth SciLifeLab Fellow
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From library to landscape: integrative annotation workflows for compound libraries in drug repurposing.
Reinshagen J, Seashore-Ludlow B, Gadiya Y, ..., Zaliani A, Ballante F
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Evaluation of maSSS/maSES-PEG2-RM26 for their potential therapeutic use after labeling with Re-188. Could their [99mTc]Tc-labeled counterparts be used to estimate dosimetry?
Kanellopoulos P, Yu Q, Abouzayed A, ..., Tolmachev V, Orlova A
EJNMMI Radiopharm Chem 10 (1) 3 [2025-01-17; online 2025-01-17]
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Anti-correlation of LacI association and dissociation rates observed in living cells.
Kandavalli V, Zikrin S, Elf J, Jones D
Nat Commun 16 (1) 764 [2025-01-17; online 2025-01-17]
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A spatiotemporal atlas of human spermatogenesis
Lindskog C, Hikmet F, Méar L, ..., Stukenborg JB, Uhlén M
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Simultaneous polyclonal antibody sequencing and epitope mapping by cryo electron microscopy and mass spectrometry – a perspective
Schulte D, Šiborová M, Käll L, Snijder J
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Protocol to infer off-target effects of drugs on cellular signaling using interactome-based deep learning.
Meimetis N, Lauffenburger DA, Nilsson A
STAR Protoc 6 (1) 103573 [2025-01-16; online 2025-01-16]
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Immune dynamics throughout life in relation to sex hormones and perspectives gained from gender-affirming hormone therapy.
Yalcinkaya A, Yalcinkaya R, Sardh F, Landegren N
Front Immunol 15 (-) 1501364 [2025-01-16; online 2025-01-16]
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Engineering cardiolipin binding to an artificial membrane protein reveals determinants for lipid-mediated stabilization
Abramsson ML, Corey RA, Škerle J, ..., Stansfeld PJ, Landreh M
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Abramsson ML, Corey RA, Škerle J, ..., Stansfeld PJ, Landreh M
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Whole-genome duplication increases genetic diversity and load in outcrossing Arabidopsis
Vlček J, Hämälä T, Cobo CV, ..., Yant L, Kolář F
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Liquid crystal nanoparticles for oral combination antibiotic therapies: A strategy towards protecting commensal gut bacteria during treatment.
He X, Karlsson PA, Xiong R, ..., Bergström CAS, Hubert M
J Colloid Interface Sci 678 (Pt B) 287-300 [2025-01-15; online 2024-08-31]
Ruisheng Xiong SciLifeLab Fellow
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Lipoproteins and lipoprotein lipid composition are associated with stages of dysglycemia and subclinical coronary atherosclerosis.
Gigante B, Chen Q, Björkbacka H, ..., Haglöw JT, Östgren CJ
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2D, or not 2D? Investigating Vertical Signal Integrity of Tissue Slices
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The Progression of Mycosis Fungoides During Treatment with Mogamulizumab: A BIO-MUSE Case Study of the Tumor and Immune Response in Peripheral Blood and Tissue.
Johansson A, Kalliara E, Belfrage E, ..., Drott K, Ek S
Biomedicines 13 (1) - [2025-01-14; online 2025-01-14]
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Prenatal and early childhood exposure to antibiotics or gastric acid inhibitors and increased risk of epilepsy: A nationwide population-based study
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Chembiochem 26 (2) - [2025-01-14; online 2025-01-29]
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Conformational Selection in Enzyme-Catalyzed Depolymerization of Bio-based Polyesters.
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Chembiochem 26 (2) e202400456 [2025-01-14; online 2024-09-17]
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Advancing Chronic Liver Disease Diagnoses: Targeted Proteomics for the Non-Invasive Detection of Fibrosis
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Livers 5 (1) 2 [2025-01-14; online 2025-01-14]
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Characterization of the oxygen-tolerant formate dehydrogenase from Clostridium carboxidivorans.
Brouwer EM, Medipally HKR, Schwab S, ..., Nowaczyk MM, Hagemann M
Front Microbiol 15 (-) 1527626 [2025-01-13; online 2025-01-13]
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Herlemann DPR, Delgado LF, Riedinger DJ, ..., Rakowski M, Labrenz M
Environ Microbiome 20 (1) 2 [2025-01-11; online 2025-01-11]
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White matter integrity upon progesterone antagonism in individuals with premenstrual dysphoric disorder: A randomized placebo-controlled diffusion tensor imaging study.
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Prog Neuropsychopharmacol Biol Psychiatry 136 (-) 111179 [2025-01-10; online 2024-10-23]
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Haloi N, Eriksson Lidbrink S, Howard RJ, Lindahl E
Sci Adv 11 (2) eadq3788 [2025-01-10; online 2025-01-08]
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Two independent translocation modes drive neural stem cell dissemination into the human fetal cortex
Wimmer R, Lestienne P, Brunet C, ..., Guimiot F, Baffet AD
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Influenza A Virus H7 nanobody recognizes a conserved immunodominant epitope on hemagglutinin head and confers heterosubtypic protection.
Chen ZS, Huang HC, Wang X, ..., Zhu Q, Angeletti D
Nat Commun 16 (1) 432 [2025-01-09; online 2025-01-09]
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Müller I, Thörn F, Rajan S, ..., Irestedt M, Jønsson K
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Cardiovascular events following coronavirus disease 2019 vaccination in adults: a nationwide Swedish study.
Xu Y, Li H, Santosa A, ..., Gisslén M, Nyberg F
Eur. Heart J. 46 (2) 147-157 [2025-01-07; online 2024-09-30]
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Zhong H, Han W, Gomez-Cabrero D, ..., Cui G, Aranda M
Nucleic Acids Res. 53 (1) - [2025-01-07; online 2025-01-09]
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Paysan-Lafosse T, Andreeva A, Blum M, ..., Wood V, Bateman A
Nucleic Acids Res. 53 (D1) D523-D534 [2025-01-06; online 2024-11-14]
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Targeting mutant p53: Evaluation of novel anti-p53R175H monoclonal antibodies as diagnostic tools.
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Sci Rep 15 (1) 1014 [2025-01-06; online 2025-01-06]
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Yulug B, Altay O, Li X, ..., Uhlén M, Mardinoglu A
Brain Commun 7 (1) fcae478 [2025-01-06; online 2025-01-06]
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Clarke AW, Høye E, Hembrom AA, ..., Peterson KJ, Fromm B
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Improving taxonomic inference from ancient environmental metagenomes by masking microbial-like regions in reference genomes.
Oskolkov N, Jin C, Clinton SL, ..., Heintzman PD, van der Valk T
Gigascience 14 (-) - [2025-01-06; online 2025-10-03]
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Analysis-ready VCF at Biobank scale using Zarr.
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Sultana S, Bruns S, Pacheco-Valenciana A, ..., Garcia S, Wienhausen G
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Two decades of bacterial ecology and evolution in a freshwater lake.
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Sarahi Garcia SciLifeLab Fellow
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The human and non-human primate developmental GTEx projects.
Coorens THH, Guillaumet-Adkins A, Kovner R, ..., Van Hoose PM, dGTEx Consortium
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The Human Pathology Atlas for deciphering the prognostic features of human cancers.
Yuan M, Zhang C, Von Feilitzen K, ..., Uhlén M, Mardinoglu A
EBioMedicine 111 (-) 105495 [2025-01-00; online 2024-12-10]
Adil Mardinoglu SciLifeLab Fellow
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Ten simple rules for good model-sharing practices.
Kherroubi Garcia I, Erdmann C, Gesing S, ..., Papin J, Rao Y
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Targeting MarA N-terminal domain dynamics to prevent DNA binding.
Corbella M, Moreira C, Bello-Madruga R, ..., Blair JMA, Sancho-Vaello E
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TRACERx analysis identifies a role for FAT1 in regulating chromosomal instability and whole-genome doubling via Hippo signalling.
Lu WT, Zalmas LP, Bailey C, ..., Kanu N, Swanton C
Nat. Cell Biol. 27 (1) 154-168 [2025-01-00; online 2024-12-30]
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Proteomic signatures of Alzheimer's disease and Lewy body dementias: A comparative analysis.
Canal-Garcia A, Branca RM, Francis PT, ..., Pereira JB, Bereczki E
Alzheimers Dement 21 (1) e14375 [2025-01-00; online 2024-12-23]
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Progestagens and progesterone receptor modulation: Effects on the brain, mood, stress, and cognition in females.
Bencker C, Gschwandtner L, Nayman S, ..., Bixo M, Comasco E
Front Neuroendocrinol 76 (-) 101160 [2025-01-00; online 2024-11-06]
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Post-injury treatment with 7,8-dihydroxyflavone attenuates white matter pathology in aged mice following focal traumatic brain injury.
Michalettos G, Clausen F, Rostami E, Marklund N
Neurotherapeutics 22 (1) e00472 [2025-01-00; online 2024-10-20]
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Population pharmacokinetic modelling of cetirizine concentrations in human breast milk-A contribution from the ConcePTION project.
Melander E, Nielsen EI, Lindqvist A, ..., Spigset O, Nordeng H
Basic Clin. Pharmacol. Toxicol. 136 (1) e14100 [2025-01-00; online 2024-11-04]
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Pathways From Early Life Adversities to Youth Marginalization: A Longitudinal Study of Youth Not in Education, Employment, or Training.
Kingsbury M, Alaie I, Clayborne Z, ..., Nilsen W, Colman I
J Adolesc Health 76 (1) 105-114 [2025-01-00; online 2024-10-02]
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European Journal of Cancer Care 2025 (1) - [2025-01-00; online 2025-06-14]
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Mitochondrial DNA abundance and circulating metabolomic profiling: Multivariable-adjusted and Mendelian randomization analyses in UK Biobank.
Luo J, le Cessie S, Willems van Dijk K, ..., van Heemst D, Noordam R
Mitochondrion 80 (-) 101991 [2025-01-00; online 2024-11-24]
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Liver X receptor unlinks intestinal regeneration and tumorigenesis.
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International multicenter validation of AI-driven ultrasound detection of ovarian cancer.
Christiansen F, Konuk E, Ganeshan AR, ..., Smith K, Epstein E
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Thorén A, Franko MA, Joelsson-Alm E, ..., Djärv T, Spångfors M
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eNeuro 12 (1) - [2025-01-00; online 2025-01-23]
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Disease characteristics and outcomes of acute myeloid leukemia in germline RUNX1 deficiency (Familial Platelet Disorder with associated Myeloid Malignancy).
Ernst MPT, Versluis J, Valk PJM, ..., Ripperger T, Raaijmakers MHGP
Hemasphere 9 (1) e70057 [2025-01-00; online 2025-01-16]
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Dietary Fiber Intake and Risk of Advanced and Aggressive Forms of Prostate Cancer: A Pooled Analysis of 15 Prospective Cohort Studies.
Sidahmed E, Freedland SJ, Wang M, ..., Genkinger JM, Smith-Warner SA
J Acad Nutr Diet 125 (1) 11-23.e22 [2025-01-00; online 2024-04-16]
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Deep CRISPR mutagenesis characterizes the functional diversity of TP53 mutations.
Funk JS, Klimovich M, Drangenstein D, ..., Joerger AC, Stiewe T
Nat. Genet. 57 (1) 140-153 [2025-01-00; online 2025-01-07]
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Chemogenomic Screening in a Patient-Derived 3D Fatty Liver Disease Model Reveals the CHRM1-TRPM8 Axis as a Novel Module for Targeted Intervention.
Youhanna S, Kemas AM, Wright SC, ..., Sundström M, Lauschke VM
Adv Sci (Weinh) 12 (3) e2407572 [2025-01-00; online 2024-11-28]
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Capacity and limitations of microfluidic flow to increase solute transport in three-dimensional cell cultures.
Bonneuil WV, Katiyar N, Tenje M, Bagheri S
J R Soc Interface 22 (222) 20240463 [2025-01-00; online 2025-01-29]
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Bacteria use exogenous peptidoglycan as a danger signal to trigger biofilm formation.
Vaidya S, Saha D, Rode DKH, ..., Cava F, Drescher K
Nat. Microbiol 10 (1) 144-157 [2025-01-00; online 2025-01-03]
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Aurora kinase B is required for growth and expansion of medulloblastoma cells in the tissue context.
Gries A, Santhana Kumar K, Kuttler F, ..., Allalou A, Baumgartner M
Neoplasia 59 (-) 101078 [2025-01-00; online 2024-11-08]
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A comprehensive human embryo reference tool using single-cell RNA-sequencing data.
Zhao C, Plaza Reyes A, Schell JP, ..., Petropoulos S, Lanner F
Nat. Methods 22 (1) 193-206 [2025-01-00; online 2024-11-14]
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Unveiling Driver Modules in Lung Cancer: A Clustering-Based Gene-Gene Interaction Network Analysis
Taheri G, Szalai M, Habibi M, Papapetrou P
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DDLS Fellow Golnaz Taheri
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The Utility of Deep Learning for Modeling Seasonal Biodiversity Changes Across the Landscape
Baggström A, Goodsell R, van Dijk L, ..., Tack A, Andermann T
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DDLS Fellow Tobias Andermann
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Strategies for taxonomic and functional annotation of metagenomes
Abramova A, Bengtsson-Palme J
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DDLS Fellow Johan Bengtsson-Palme
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Recognition of breast cancer from heterogeneous ultrasound images: A multi-level deep learning approach
Duong LT, Doan TTH, Bui AMT, Nguyen PT
Informatics in Medicine Unlocked 59 (-) 101698 [2025-00-00; online 2025-00-00]
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Polythieno[3,4- ]pyrazine: pathways to metallic charge transport
Farka D, Leeb E, Moreda OI, ..., Stifter D, Sariciftci NS
J. Mater. Chem. A 13 (30) 25131-25145 [2025-00-00; online 2025-00-00]
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PKLR-Modulating Compounds Show Promising Effects for the Treatment of Hepatocellular Carcinoma
Kim W, Jin H, Miao P, ..., Zhang C, Mardinoglu A
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Adil Mardinoglu SciLifeLab Fellow
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Neurochemistry of the Central Nervous System
Ascenzi BM, Myers MW, Buccilli B
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Multi-Omics Analysis Reveals Key Factors Associated with the Parkinson's Disease Severity
Mardinoglu A, Jin H, Meng L, ..., Zhang C, Uhlen M
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Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
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Minimising Source-Plate Swaps for Robotised Compound Dispensing in Microplates
Gindullin R, Francisco Rodríguez MA, Seashore-Ludlow B, Spjuth O
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Menstrual cycle-related changes in the human brain
Pletzer B, Comasco E, Hidalgo-Lopez E, ..., Sundström-Poromaa I, Derntl B
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Erika Comasco SciLifeLab Fellow
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Limited Effects of Tetracycline and Ciprofloxacin on Soil Bacterial Communities
Wenne M, Abramova A, Bengtsson-Palme J
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DDLS Fellow Johan Bengtsson-Palme
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Learning conformational ensembles of proteins based on backbone geometry
Wolf N, Seute L, Viliuga V, ..., Stühmer J, Gräter F
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Interdisciplinary Study on Drug-Induced-Phospholipidosis of Repurposing Libraries Through Machine Learning and Experimental Evaluation in Different Cell Lines
Kuzikov M, Kalman A, Reinshagen J, ..., Gribbon P, Zaliani A
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Engineering Kyat1 to Enhance Msc Metabolism for Selenium-Based Cancer Therapy
Selvam A, Sun R, Sandalova T, ..., Achour A, Björnstedt M
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Distinct Spatiotemporal Inflammatory Programs Underlying Experimental Chronic Colitis
Fransson J, Sorini C, Castillo F, ..., Smith P, Villablanca EJ
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SciLifeLab Data Centre
Publications 9.5.1