Lindblad-Toh K

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Family name Lindblad-Toh
Given name Kerstin
Initials K
ORCID

ORCID 0000-0001-8338-0253
Affiliations Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, 751 32, Uppsala, Sweden.
Broad Institute of MIT and Harvard, Cambridge, MA, 02139, USA.

35 publications

PubMed DOI Crossref
Genetic Adaptation to Brackish Water and Spawning Season in European Cisco.
Deng Q, Goodall J, Bergenius Nord M, ..., Pettersson OV, Andersson L
Mol. Ecol. 34 (20) e70094 [2025-10-00; online 2025-09-03]
PubMed DOI Crossref
Genome-wide analyses identify 30 loci associated with obsessive-compulsive disorder.
Strom NI, Gerring ZF, Galimberti M, ..., Derks EM, Mattheisen M
Nat. Genet. 57 (6) 1389-1401 [2025-06-00; online 2025-05-13]
PubMed DOI Crossref
Genome-wide analyses identify 30 loci associated with obsessive-compulsive disorder.
Strom NI, Gerring ZF, Galimberti M, ..., Derks EM, Mattheisen M
medRxiv - (-) - [2025-04-08; online 2025-04-08]
PubMed DOI Crossref
A burden of rare copy number variants in obsessive-compulsive disorder.
Halvorsen MW, de Schipper E, Bäckman J, ..., Mataix-Cols D, Crowley JJ
Mol. Psychiatry 30 (4) 1510-1517 [2025-04-00; online 2024-10-27]
PubMed DOI Crossref
Interpreting mammalian synonymous site conservation in light of the unwanted transcript hypothesis.
Christmas MJ, Dong MX, Meadows JRS, Kozyrev SV, Lindblad-Toh K
Nat Commun 16 (1) 2007 [2025-02-27; online 2025-02-27]
PubMed DOI Crossref
Hemangiosarcoma Cells Promote Conserved Host-derived Hematopoietic Expansion.
Kim JH, Schulte AJ, Sarver AL, ..., Kaufman DS, Modiano JF
Cancer Res Commun 4 (6) 1467-1480 [2024-06-11; online 2024-05-17]
PubMed DOI Crossref
Identification of constrained sequence elements across 239 primate genomes.
Kuderna LFK, Ulirsch JC, Rashid S, ..., Marques Bonet T, Farh KK
Nature 625 (7996) 735-742 [2024-01-00; online 2023-11-29]
PubMed DOI Crossref
Using evolutionary constraint to define novel candidate driver genes in medulloblastoma.
Roy A, Sakthikumar S, Kozyrev SV, ..., Lindblad-Toh K, Forsberg-Nilsson K
Proc. Natl. Acad. Sci. U.S.A. 120 (33) e2300984120 [2023-08-15; online 2023-08-07]
PubMed DOI Crossref
Genome sequencing of 2000 canids by the Dog10K consortium advances the understanding of demography, genome function and architecture.
Meadows JRS, Kidd JM, Wang GD, ..., Zhang YP, Ostrander EA
Genome Biol. 24 (1) 187 [2023-08-15; online 2023-08-15]
PubMed DOI Crossref
The contribution of historical processes to contemporary extinction risk in placental mammals.
Wilder AP, Supple MA, Subramanian A, ..., Ryder OA, Shapiro B
Science (New York, N.Y.) 380 (6643) eabn5856 [2023-04-28; online 2023-04-28]
PubMed DOI Crossref
A genomic timescale for placental mammal evolution.
Foley NM, Mason VC, Harris AJ, ..., Springer MS, Murphy WJ
Science (New York, N.Y.) 380 (6643) eabl8189 [2023-04-28; online 2023-04-28]
PubMed DOI Crossref
Insights into mammalian TE diversity through the curation of 248 genome assemblies.
Osmanski AB, Paulat NS, Korstian J, ..., Lindblad-Toh K, Ray DA
Science (New York, N.Y.) 380 (6643) eabn1430 [2023-04-28; online 2023-04-28]
PubMed DOI Crossref
Leveraging base-pair mammalian constraint to understand genetic variation and human disease.
Sullivan PF, Meadows JRS, Gazal S, ..., Karlsson EK, Lindblad-Toh K
Science (New York, N.Y.) 380 (6643) eabn2937 [2023-04-28; online 2023-04-28]
PubMed DOI Crossref
Relating enhancer genetic variation across mammals to complex phenotypes using machine learning.
Kaplow IM, Lawler AJ, Schäffer DE, ..., Meyer WK, Pfenning AR
Science (New York, N.Y.) 380 (6643) eabm7993 [2023-04-28; online 2023-04-28]
PubMed DOI Crossref
Mammalian evolution of human cis-regulatory elements and transcription factor binding sites.
Andrews G, Fan K, Pratt HE, ..., Moore JE, Weng Z
Science (New York, N.Y.) 380 (6643) eabn7930 [2023-04-28; online 2023-04-28]
PubMed DOI Crossref
Evolutionary constraint and innovation across hundreds of placental mammals.
Christmas MJ, Kaplow IM, Genereux DP, ..., Lindblad-Toh K, Karlsson EK
Science (New York, N.Y.) 380 (6643) eabn3943 [2023-04-28; online 2023-04-28]
PubMed DOI Crossref
Three-dimensional genome rewiring in loci with human accelerated regions.
Keough KC, Whalen S, Inoue F, ..., Pollen A, Pollard KS
Science (New York, N.Y.) 380 (6643) eabm1696 [2023-04-28; online 2023-04-28]
PubMed DOI Crossref
​Comparative genomics of Balto, a famous historic dog, captures lost diversity of 1920s sled dogs.
Moon KL, Huson HJ, Morrill K, ..., Karlsson EK, Shapiro B
Science (New York, N.Y.) 380 (6643) eabn5887 [2023-04-28; online 2023-04-28]
PubMed DOI Crossref
Integrating gene annotation with orthology inference at scale.
Kirilenko BM, Munegowda C, Osipova E, ..., Zoonomia Consortium‡ , Hiller M
Science (New York, N.Y.) 380 (6643) eabn3107 [2023-04-28; online 2023-04-28]
PubMed DOI Crossref
The functional and evolutionary impacts of human-specific deletions in conserved elements.
Xue JR, Mackay-Smith A, Mouri K, ..., Sabeti PC, Reilly SK
Science (New York, N.Y.) 380 (6643) eabn2253 [2023-04-28; online 2023-04-28]
PubMed DOI Crossref
Multiple Genetic Loci Associated with Pug Dog Thoracolumbar Myelopathy.
Brander G, Rohdin C, Bianchi M, ..., Lindblad-Toh K, Tengvall K
Genes (Basel) 14 (2) - [2023-02-01; online 2023-02-01]
DOI Crossref
Insights into mammalian TE diversity via the curation of 248 mammalian genome assemblies
Osmanski AB, Paulat NS, Korstian J, ..., Karlsson EK, Ray DA
- - (-) - [2022-12-30; online 2022-12-30]
PubMed DOI Crossref
Bayesian model and selection signature analyses reveal risk factors for canine atopic dermatitis.
Tengvall K, Sundström E, Wang C, ..., Andersson G, Lindblad-Toh K
Commun Biol 5 (1) 1348 [2022-12-08; online 2022-12-08]
DOI Crossref
Three-dimensional genome re-wiring in loci with Human Accelerated Regions
Keough KC, Whalen S, Inoue F, ..., Pollen A, Pollard KS
- - (-) - [2022-10-05; online 2022-10-05]
PubMed DOI Crossref
Evolution of the ancestral mammalian karyotype and syntenic regions.
Damas J, Corbo M, Kim J, ..., Zoonomia Consortium , Lewin HA
Proc. Natl. Acad. Sci. U.S.A. 119 (40) e2209139119 [2022-10-04; online 2022-09-26]
PubMed DOI Crossref
Contribution of Rare Genetic Variation to Disease Susceptibility in a Large Scandinavian Myositis Cohort.
Bianchi M, Kozyrev SV, Notarnicola A, ..., Lindblad-Toh K, Lundberg IE
Arthritis & rheumatology (Hoboken, N.J.) 74 (2) 342-352 [2022-02-00; online 2021-12-23]
PubMed DOI Crossref
Why sequence all eukaryotes?
Blaxter M, Archibald JM, Childers AK, ..., Zhang G, Lewin HA
Proc. Natl. Acad. Sci. U.S.A. 119 (4) - [2022-01-25; online 2022-01-20]
PubMed DOI Crossref
The Earth BioGenome Project 2020: Starting the clock.
Lewin HA, Richards S, Lieberman Aiden E, ..., Yoder AD, Zhang G
Proc. Natl. Acad. Sci. U.S.A. 119 (4) - [2022-01-25; online 2022-01-20]
PubMed DOI Crossref
Standards recommendations for the Earth BioGenome Project.
Lawniczak MKN, Durbin R, Flicek P, ..., Lewin HA, Richards S
Proc. Natl. Acad. Sci. U.S.A. 119 (4) - [2022-01-25; online 2022-01-20]
PubMed DOI Crossref
3D genomics across the tree of life reveals condensin II as a determinant of architecture type.
Hoencamp C, Dudchenko O, Elbatsh AMO, ..., Lieberman Aiden E, Rowland BD
Science (New York, N.Y.) 372 (6545) 984-989 [2021-05-28; online 2021-05-29]
DOI Crossref
The meadow jumping mouse genome and transcriptome suggest mechanisms of hibernation
Cong Q, Brem EA, Zhang J, ..., Malaney JL, Israelsen WJ
- - (-) - [2020-11-03; online 2020-11-03]
PubMed DOI Crossref
Broad host range of SARS-CoV-2 predicted by comparative and structural analysis of ACE2 in vertebrates.
Damas J, Hughes GM, Keough KC, ..., Karlsson EK, Lewin HA
Proc. Natl. Acad. Sci. U.S.A. 117 (36) 22311-22322 [2020-09-08; online 2020-08-21]
DOI Crossref
Genomically Complex Human Angiosarcoma and Canine Hemangiosarcoma Establish Convergent Angiogenic Transcriptional Programs Driven by Novel Gene Fusions
Kim JH, Megquier K, Thomas R, ..., Lindblad-Toh K, Modiano JF
- - (-) - [2020-08-12; online 2020-08-12]
DOI Crossref
A new long-read dog assembly uncovers thousands of exons and functional elements missing in the previous reference
Wang C, Wallerman O, Arendt ML, ..., Meadows JRS, Lindblad-Toh K
- - (-) - [2020-07-02; online 2020-07-02]
PubMed DOI Crossref
Transcriptomes from German shepherd dogs reveal differences in immune activity between atopic dermatitis affected and control skin.
Tengvall K, Bergvall K, Olsson M, ..., Lindblad-Toh K, Andersson G
Immunogenetics 72 (5) 315-323 [2020-07-00; online 2020-06-18]
SciLifeLab Data Centre
Publications 9.5.1