Höijer I

Accurate characterization of CRISPR-Cas9 genome editing outcomes and mosaicism with near-perfect long reads

Höijer I, van Schendel R, Emmanouilidou A, ..., den Hoed M, Ameur A

- - (-) - [2025-09-09; online 2025-09-09]

Visualization and analysis of medically relevant tandem repeats in nanopore sequencing of control cohorts with pathSTR.

De Coster W, Höijer I, Bruggeman I, ..., Ameur A, Rademakers R

Genome Res 34 (11) 2074-2080 [2024-11-20; online 2024-11-20]

Medically relevant tandem repeats in nanopore sequencing of control cohorts

De Coster W, Höijer I, Bruggeman I, ..., Ameur A, Rademakers R

- - (-) - [2024-03-14; online 2024-03-14]

Towards routine long-read sequencing for rare disease: a national pilot study on chromosomal rearrangements

Eisfeldt J, Ameur A, Lenner F, ..., Feuk L, Lindstrand A

- - (-) - [2023-12-17; online 2023-12-17]

CRISPR-Cas9 induces large structural variants at on-target and off-target sites in vivo that segregate across generations.

Höijer I, Emmanouilidou A, Östlund R, ..., den Hoed M, Ameur A

Nat Commun 13 (1) 627 [2022-02-02; online 2022-02-02]

CRISPR-Cas9 induces large structural variants at on-target and off-target sites in vivo that segregate across generations

Höijer I, Emmanouilidou A, Östlund R, ..., den Hoed M, Ameur A

- - (-) - [2021-10-05; online 2021-10-05]

Amplification-free long-read sequencing reveals unforeseen CRISPR-Cas9 off-target activity.

Höijer I, Johansson J, Gudmundsson S, ..., Gyllensten U, Ameur A

Genome Biol. 21 (1) 290 [2020-12-01; online 2020-12-01]

Xdrop: Targeted sequencing of long DNA molecules from low input samples using droplet sorting.

Madsen EB, Höijer I, Kvist T, Ameur A, Mikkelsen MJ

Hum. Mutat. 41 (9) 1671-1679 [2020-09-00; online 2020-06-29]

Amplification-free long read sequencing reveals unforeseen CRISPR-Cas9 off-target activity

Höijer I, Johansson J, Gudmundsson S, ..., Gyllensten U, Ameur A

- - (-) - [2020-02-09; online 2020-02-09]

De Novo Assembly of Two Swedish Genomes Reveals Missing Segments from the Human GRCh38 Reference and Improves Variant Calling of Population-Scale Sequencing Data.

Ameur A, Che H, Martin M, ..., Feuk L, Gyllensten U

Genes (Basel) 9 (10) - [2018-10-09; online 2018-10-09]

Detailed analysis of HTT repeat elements in human blood using targeted amplification-free long-read sequencing.

Höijer I, Tsai YC, Clark TA, ..., Gyllensten U, Ameur A

Hum. Mutat. 39 (9) 1262-1272 [2018-09-00; online 2018-07-12]