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den Hoed M
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Family name
den Hoed
Given name
Marcel
Initials
M
ORCID
ORCID
0000-0001-8081-428X
Affiliations
Department of Immunology, Genetics and Pathology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
11 publications
DOI
Crossref
Accurate characterization of CRISPR-Cas9 genome editing outcomes and mosaicism with near-perfect long reads
Höijer I
,
van Schendel R
,
Emmanouilidou A
, ...,
den Hoed M
,
Ameur A
-
-
(-) - [2025-09-09; online 2025-09-09]
DOI
Crossref
Mosaic loss of chromosome Y and coronary atherosclerosis in men: insights into sex differences in cardiovascular risk from the SCAPIS study
Bjurling J,
Malinovschi A
,
Jernberg T
, ..., Halvardson J, Forsberg LA
-
-
(-) - [2025-07-14; online 2025-07-14]
PubMed
DOI
Crossref
GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification.
Lagou V, Jiang L, Ulrich A, ...,
Prokopenko I
, Meta-Analysis of Glucose and Insulin-Related Traits Consortium (MAGIC)
Nat. Genet.
55
(9) 1448-1461 [2023-09-00; online 2023-09-07]
DOI
Crossref
Kita crispants for systematic image-based genetic screens of complex traits in zebrafish larvae
Mazzaferro E,
Metzendorf C
, Zhang H, ..., Allalou A,
den Hoed M
-
-
(-) - [2023-07-24; online 2023-07-24]
PubMed
DOI
Crossref
Loss of RREB1 in pancreatic beta cells reduces cellular insulin content and affects endocrine cell gene expression.
Mattis KK
,
Krentz NAJ
,
Metzendorf C
, ...,
den Hoed M
,
Gloyn AL
Diabetologia
66
(4) 674-694 [2023-04-00; online 2023-01-12]
PubMed
DOI
Crossref
Dysregulation of macrophage PEPD in obesity determines adipose tissue fibro-inflammation and insulin resistance.
Pellegrinelli V
, Rodriguez-Cuenca S, Rouault C, ...,
Clément K
,
Vidal-Puig A
Nat Metab
4
(4) 476-494 [2022-04-00; online 2022-04-25]
DOI
Crossref
Physical activity and sedentary behavior; mechanistic insights and role in disease prevention
Hoed Md
,
Wang Z
,
Emmerich A
, ..., Thomis M,
Loos R
-
-
(-) - [2021-12-16; online 2021-12-16]
PubMed
DOI
Crossref
Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour.
Mills MC
,
Tropf FC
,
Brazel DM
, ...,
Barban N
,
Day FR
Nat Hum Behav
5
(12) 1717-1730 [2021-12-00; online 2021-07-01]
DOI
Crossref
CRISPR-Cas9 induces large structural variants at on-target and off-target sites in vivo that segregate across generations
Höijer I
,
Emmanouilidou A
, Östlund R, ...,
den Hoed M
,
Ameur A
-
-
(-) - [2021-10-05; online 2021-10-05]
PubMed
DOI
Crossref
Genome-wide discovery of genetic loci that uncouple excess adiposity from its comorbidities.
Huang LO
,
Rauch A
, Mazzaferro E, ...,
Kilpeläinen TO
,
Loos RJF
Nat Metab
3
(2) 228-243 [2021-02-00; online 2021-02-22]
PubMed
DOI
Crossref
Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.
Malik R, Chauhan G,
Traylor M
, ..., Debette S,
Dichgans M
Nat. Genet.
51
(7) 1192-1193 [2019-07-00; online 2019-06-05]
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Publications
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