Seashore-Ludlow B

Family name	Seashore-Ludlow
Given name	Brinton
Initials	B
ORCID	ORCID 0000-0001-8658-5967
Affiliations

20 publications

DOI Crossref

Interdisciplinary Study on Drug-Induced-Phospholipidosis of Repurposing Libraries through Machine Learning and Experimental Evaluation in Different Cell Lines

Wendt J, Kuzikov M, Kalman A, ..., Gribbon P, Zaliani A

- - (-) - [2025-09-12]

DOI Crossref

From Library to Landscape: Integrative Annotation Workflows for Compound Libraries in Drug Repurposing

Reinshagen J, Seashore-Ludlow B, Gadiya Y, ..., Zaliani A, Ballante F

- - (-) - [2025-07-29; online 2025-07-29]

PubMed DOI Crossref

Ex Vivo Drug Sensitivity of Pleural Effusion-Derived Cells from Lung Cancer and Pleural Mesothelioma Patients Is Linked to Clinical Response.

Hutyra-Gram Ötvös R, Krynska H, Gudoityte G, ..., Seashore-Ludlow B, Dobra K

Cancers (Basel) 17 (14) - [2025-07-16; online 2025-07-16]

DOI Crossref

Interdisciplinary Study on Drug-Induced-Phospholipidosis of Repurposing Libraries through Machine Learning and Experimental Evaluation in Different Cell Lines

Kuzikov M, Kalman A, Reinshagen J, ..., Gribbon P, Zaliani A

- - (-) - [2025-07-09; online 2025-07-09]

PubMed DOI Crossref

Targeted inhibition of WIP1 and histone H3K27 demethylase activity synergistically suppresses neuroblastoma growth.

Treis D, Lundberg KI, Bell N, ..., Johnsen JI, Wickström M

Cell Death Dis 16 (1) 318 [2025-04-19; online 2025-04-19]

PubMed DOI Crossref

Evaluating feature extraction in ovarian cancer cell line co-cultures using deep neural networks.

Sharma O, Gudoityte G, Minozada R, ..., Paavolainen L, Seashore-Ludlow B

Commun Biol 8 (1) 303 [2025-02-25; online 2025-02-25]

DOI Crossref

High-content morphological profiling by Cell Painting in 3D spheroids

Ringers C, Holmberg D, Flobak Å, ..., Carreras Puigvert J, Spjuth O

- - (-) - [2025-02-08; online 2025-02-08]

DOI Crossref

Minimising Source-Plate Swaps for Robotised Compound Dispensing in Microplates

Gindullin R, Francisco Rodríguez MA, Seashore-Ludlow B, Spjuth O

- - (-) 256-273 [2025-00-00; online 2025-06-29]

PubMed DOI Crossref

Delineating functional and molecular impact of ex vivo sample handling in precision medicine.

Struyf N, Österroos A, Vesterlund M, ..., Seashore-Ludlow B, Erkers T

NPJ Precis Oncol 8 (1) 38 [2024-02-19; online 2024-02-19]

DOI Crossref

SMAC mimetics overcome apoptotic resistance in ovarian cancer through MSLN-TNF alpha axis

Coelho R, Seashore-Ludlow B, Schütz S, ..., Heinzelmann-Schwarz V, Jacob F

- - (-) - [2024-01-26; online 2024-01-26]

PubMed DOI Crossref

The drug efficacy testing in 3D cultures platform identifies effective drugs for ovarian cancer patients.

Åkerlund E, Gudoityte G, Moussaud-Lamodière E, ..., Joneborg U, Seashore-Ludlow B

NPJ Precis Oncol 7 (1) 111 [2023-10-31; online 2023-10-31]

DOI Crossref

Delineating functional and molecular impact of ex vivo sample handling in precision medicine

Erkers T, Struyf N, Arnroth C, ..., Kallioniemi O, Seashore-Ludlow B

- - (-) - [2023-07-26; online 2023-07-26]

DOI Crossref

The Drug Efficacy Testing in Ex Vivo 3D Cultures (DETECt) platform enables rapid identification of effective drugs and drug combinations for ovarian cancer patients

Seashore-Ludlow B, Åkerlund E, Gudoityte G, ..., Kallioniemi O, Joneborg U

- - (-) - [2023-04-12; online 2023-04-12]

PubMed DOI Crossref

A Portable, Negative-Pressure Actuated, Dynamically Tunable Microfluidic Droplet Generator.

Trossbach M, de Lucas Sanz M, Seashore-Ludlow B, Joensson HN

Micromachines (Basel) 13 (11) - [2022-10-25; online 2022-10-25]

DOI Crossref

High-throughput cell spheroid production and assembly analysis by microfluidics and deep learning

Trossbach M, Åkerlund E, Langer K, Seashore-Ludlow B, Joensson HN

- - (-) - [2022-10-05; online 2022-10-05]

PubMed DOI Crossref

MTH1 Inhibitor TH1579 Induces Oxidative DNA Damage and Mitotic Arrest in Acute Myeloid Leukemia.

Sanjiv K, Calderón-Montaño JM, Pham TM, ..., Helleday T, Warpman Berglund U

Cancer Res. 81 (22) 5733-5744 [2021-11-15; online 2021-09-30]

PubMed DOI Crossref

Perspective on CETSA Literature: Toward More Quantitative Data Interpretation.

Seashore-Ludlow B, Axelsson H, Lundbäck T

SLAS Discov 25 (2) 118-126 [2020-02-00; online 2019-10-30]

PubMed DOI Crossref

Quantitative Interpretation of Intracellular Drug Binding and Kinetics Using the Cellular Thermal Shift Assay.

Seashore-Ludlow B, Axelsson H, Almqvist H, ..., Jonsson M, Lundbäck T

Biochemistry 57 (48) 6715-6725 [2018-12-04; online 2018-11-19]

PubMed DOI Crossref

In Situ Target Engagement Studies in Adherent Cells.

Axelsson H, Almqvist H, Otrocka M, ..., Lundbäck T, Seashore-Ludlow B

ACS chemical biology 13 (4) 942-950 [2018-04-20; online 2018-02-21]

PubMed DOI Crossref

Correlating chemical sensitivity and basal gene expression reveals mechanism of action.

Rees MG, Seashore-Ludlow B, Cheah JH, ..., Shamji AF, Schreiber SL

Nat. Chem. Biol. 12 (2) 109-116 [2016-02-00; online 2015-12-14]