Stenmark P

Giving an Enzyme Scissors: Serotonin Derivatives as Potent Organocatalytic Switches for DNA Repair Enzyme OGG1.

Varga M, Ortis F, Del Prado A, ..., Watson AJB, Michel M

J Med Chem 68 (21) 22455-22483 [2025-11-13; online 2025-10-15]

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1.

Scaletti Hutchinson E, Gustafsson Westergren R, Almlöf I, ..., Helleday T, Stenmark P

FEBS Lett. 599 (19) 2790-2801 [2025-10-00; online 2025-07-27]

Kinetic and structural characterization of NUDT15 and NUDT18 as catalysts of isoprene pyrophosphate hydrolysis.

Scaletti ER, Unterlass JE, Almlöf I, ..., Stenmark P, Jemth AS

FEBS J. 291 (19) 4301-4322 [2024-10-00; online 2024-06-29]

Bacterial transcriptional repressor NrdR – a flexible multifactorial nucleotide sensor

Rozman Grinberg I, Bimaï O, Shahid S, ..., Sjöberg BM, Logan DT

- - (-) - [2024-09-08; online 2024-09-08]

Kinetic and structural characterization of human NUDIX hydrolases NUDT15 and NUDT18 as catalysts of isoprene pyrophosphate hydrolysis

Scaletti ER, Unterlass JE, Almlöf I, ..., Stenmark P, Jemth AS

- - (-) - [2023-11-29; online 2023-11-29]

Coupling cellular drug-target engagement to downstream pharmacology with CeTEAM

Valerie NCK, Sanjiv K, Mortusewicz O, ..., Page BDG, Altun M

- - (-) - [2022-09-19; online 2022-09-19]

Front Cover: The First Structure of Human MTHFD2L and Its Implications for the Development of Isoform‐Selective Inhibitors (ChemMedChem 18/2022)

Scaletti ER, Gustafsson Westergren R, Andersson Y, ..., Helleday T, Stenmark P

ChemMedChem 17 (18) - [2022-09-16; online 2022-09-26]

The First Structure of Human MTHFD2L and Its Implications for the Development of Isoform-Selective Inhibitors.

Scaletti ER, Gustafsson Westergren R, Andersson Y, ..., Helleday T, Stenmark P

ChemMedChem 17 (18) e202200274 [2022-09-16; online 2022-07-06]

Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function.

Michel M, Benítez-Buelga C, Calvo PA, ..., de Vega M, Helleday T

Science (New York, N.Y.) 376 (6600) 1471-1476 [2022-06-24; online 2022-06-23]

Crystal structures of human PAICS reveal substrate and product binding of an emerging cancer target.

Škerlová J, Unterlass J, Göttmann M, ..., Jemth AS, Stenmark P

J Biol Chem 295 (33) 11656-11668 [2020-08-14; online 2020-06-22]

MutT homologue 1 (MTH1) removes N6-methyl-dATP from the dNTP pool.

Scaletti ER, Vallin KS, Bräutigam L, ..., Stenmark P, Jemth AS

J Biol Chem 295 (15) 4761-4772 [2020-04-10; online 2020-03-06]

Structural basis for the interaction of the chaperone Cbp3 with newly synthesized cytochrome b during mitochondrial respiratory chain assembly.

Ndi M, Masuyer G, Dawitz H, ..., Stenmark P, Ott M

J Biol Chem 294 (45) 16663-16671 [2019-11-08; online 2019-09-19]