Hank EC

Giving an Enzyme Scissors: Serotonin Derivatives as Potent Organocatalytic Switches for DNA Repair Enzyme OGG1.

Varga M, Ortis F, Del Prado A, ..., Watson AJB, Michel M

J Med Chem 68 (21) 22455-22483 [2025-11-13; online 2025-10-15]

Nucleobase catalysts for the enzymatic activation of 8-oxoguanine DNA glycosylase 1

Hank EC, D'Arcy-Evans N, Scaletti ER, ..., Helleday T, Michel M

- - (-) - [2025-01-01; online 2025-01-01]

Nucleobase catalysts for the enzymatic activation of 8-oxoguanine DNA glycosylase 1

Hank EC, D'Arcy-Evans N, Scaletti ER, ..., Helleday T, Michel M

- - (-) - [2024-05-10; online 2024-05-10]

Nucleobase catalysts for the enzymatic activation of 8-oxoguanine DNA glycosylase 1

Hank EC, D'Arcy-Evans N, Wallner O, ..., de Vega M, Michel M

- - (-) - [2023-07-26; online 2023-07-26]

Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function.

Michel M, Benítez-Buelga C, Calvo PA, ..., de Vega M, Helleday T

Science (New York, N.Y.) 376 (6600) 1471-1476 [2022-06-24; online 2022-06-23]