Zubarev RA

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Family name Zubarev
Given name Roman A
Initials RA
ORCID

ORCID 0000-0001-9839-2089
Affiliations Division of Physiological Chemistry I, Department of Medical Biochemistry and Biophysics, Karolinska Institute, SE-171 77 Stockholm, Sweden
SciLifeLab, SE-171 21 Solna, Sweden
Department of Pharmacological & Technological Chemistry, I.M. Sechenov First Moscow State Medical University, Moscow 119146, Russia

23 publications

PubMed DOI Crossref
Anti-Tumoral Treatment with Thioredoxin Reductase 1 Inhibitor Auranofin Fosters Regulatory T Cell and B16F10 Expansion in Mice.
Bonner MY, Vancsik T, Oliveira-Coelho A, ..., Arnér ESJ, Holmdahl R
Antioxidants (Basel) 14 (11) - [2025-11-11; online 2025-11-11]
PubMed DOI Crossref
Toward a Species Search Engine: KISSE Offers a Rigorous Statistical Framework for Bone Collagen Tandem Mass Spectrometry Data.
Gharibi H, Saei AA, Chernobrovkin AL, ..., Gaetani M, Zubarev RA
Adv Sci (Weinh) 12 (40) e03963 [2025-10-00; online 2025-08-11]
PubMed DOI Crossref
Role of Structural Modifications in Peptidomimetic Compounds as Potential Antimicrobial Agents against Staphylococcus aureus and Streptococcus pyogenes: Balancing Bioavailability, Safety, and Antimicrobial Activity.
Dzierżyńska M, Sawicka J, Łada K, ..., Kasprzykowski F, Rodziewicz-Motowidło S
ACS Omega 10 (30) 33435-33460 [2025-08-05; online 2025-07-22]
DOI Crossref
Is it time to retire Δ?
Zubarev RA
- - (-) - [2025-06-17; online 2025-06-17]
PubMed DOI Crossref
One-Pot Time-Induced Proteome Integral Solubility Alteration Assay for Automated and Sensitive Drug-Target Identification.
Meng Z, Saei AA, Lyu H, Gaetani M, Zubarev RA
Anal. Chem. 96 (48) 18917-18921 [2024-12-03; online 2024-11-20]
PubMed DOI Crossref
Multifaceted Proteome Analysis at Solubility, Redox, and Expression Dimensions for Target Identification.
Saei AA, Lundin A, Lyu H, ..., Gygi SP, Zubarev RA
Adv Sci (Weinh) 11 (38) e2401502 [2024-10-00; online 2024-08-09]
PubMed DOI Crossref
Gel-Assisted Proteome Position Integral Shift Assay Returns Molecular Weight to Shotgun Proteomics and Identifies Caspase 3 Substrates.
Meng Z, Saei AA, Gharibi H, ..., Gaetani M, Zubarev RA
Anal. Chem. 96 (33) 13533-13541 [2024-08-20; online 2024-08-07]
DOI Crossref
One-Pot Time-Induced Proteome Integral Solubility Alteration (OPTI-PISA) assay for automated and sensitive drug target identification
Meng Z, Saei AA, Lyu H, Gaetani M, Zubarev RA
- - (-) - [2024-08-13; online 2024-08-13]
DOI Crossref
ThermoTargetMiner as a proteome integral solubility alteration target database for prospective drugs against lung cancer
Lyu H, Gharibi H, Sokolova B, ..., Saei AA, Zubarev RA
- - (-) - [2024-08-06; online 2024-08-06]
DOI Crossref
Gel-Assisted Proteome Position Integral Shift (GAPPIS) Assay Returns Molecular Weight to Shotgun Proteomics and Identifies Novel Caspase 3 Substrates
Meng Z, Saei AA, Zhang X, ..., Gaetani M, Zubarev RA
- - (-) - [2024-02-15; online 2024-02-15]
DOI Crossref
Ultralight Ultrafast Enzymes**
Zhang X, Meng Z, Beusch CM, ..., Gaetani M, Zubarev RA
Angewandte Chemie 136 (3) - [2024-01-15; online 2023-12-07]
PubMed DOI Crossref
Ultralight Ultrafast Enzymes.
Zhang X, Meng Z, Beusch CM, ..., Gaetani M, Zubarev RA
Angew. Chem. Int. Ed. Engl. 63 (3) e202316488 [2024-01-15; online 2023-12-07]
PubMed DOI Crossref
Proteomics-Compatible Fourier Transform Isotopic Ratio Mass Spectrometry of Polypeptides.
Gharibi H, Chernobrovkin AL, Saei AA, ..., Makarov AA, Zubarev RA
Anal. Chem. 94 (43) 15048-15056 [2022-11-01; online 2022-10-17]
DOI Crossref
System-wide profiling by proteome integral solubility alteration assay of drug residence times for target characterization
Sabatier P, Beusch CM, Meng Z, Zubarev RA
- - (-) - [2022-06-27; online 2022-06-27]
DOI Crossref
Conformational Selection in Biocatalytic Plastic Degradation by PETase
Guo B, Vanga SR, Lopez-Lorenzo X, ..., Hakkarainen M, Syrén PO
ACS Catal 12 (6) 3397-3409 [2022-03-18; online 2022-03-01]
PubMed DOI Crossref
An integrative proteomics method identifies a regulator of translation during stem cell maintenance and differentiation.
Sabatier P, Beusch CM, Saei AA, ..., Rodin S, Zubarev RA
Nat Commun 12 (1) 6558 [2021-11-12; online 2021-11-12]
PubMed DOI Crossref
System-wide identification and prioritization of enzyme substrates by thermal analysis.
Saei AA, Beusch CM, Sabatier P, ..., Schüler H, Zubarev RA
Nat Commun 12 (1) 1296 [2021-02-26; online 2021-02-26]
PubMed DOI Crossref
Proteome Integral Solubility Alteration: A High-Throughput Proteomics Assay for Target Deconvolution.
Gaetani M, Sabatier P, Saei AA, ..., Lundström SL, Zubarev RA
J. Proteome Res. 18 (11) 4027-4037 [2019-11-01; online 2019-10-14]
PubMed DOI Crossref
Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation.
Visnes T, Cázares-Körner A, Hao W, ..., Boldogh I, Helleday T
Science (New York, N.Y.) 362 (6416) 834-839 [2018-11-16; online 2018-11-18]
DOI Crossref
System-wide identification and prioritization of enzyme substrates by thermal analysis (SIESTA)
Saei AA, Beusch CM, Sabatier P, ..., Schüler H, Zubarev RA
- - (-) - [2018-09-21; online 2018-09-21]
PubMed DOI Crossref
Covariation of Peptide Abundances Accurately Reflects Protein Concentration Differences.
Zhang B, Pirmoradian M, Zubarev R, Käll L
Mol. Cell Proteomics 16 (5) 936-948 [2017-05-00; online 2017-03-16]
PubMed DOI Crossref
DeMix-Q: Quantification-Centered Data Processing Workflow.
Zhang B, Käll L, Zubarev RA
Mol. Cell Proteomics 15 (4) 1467-1478 [2016-04-00; online 2016-01-04]
PubMed
Diagnostic urinary proteome profile for immunoglobulin a nephropathy.
Samavat S, Kalantari S, Nafar M, ..., Parvin M, Zubarev RA
Iran J Kidney Dis 9 (3) 239-248 [2015-05-00; online 2015-05-10]
Affiliated researcher
SciLifeLab Data Centre
Publications 9.5.1