Casanova JL

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Family name Casanova
Given name Jean-Laurent
Initials JL
ORCID

ORCID 0000-0002-7782-4169
Affiliations Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Santé et de la Recherche Médicale (INSERM) U1163, Necker Hospital for Sick Children , Paris, France.
Paris Cité University, Imagine Institute , Paris, France.
St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University , New York, NY, USA.
Howard Hughes Medical Institute , New York, NY, USA.
Department of Pediatrics, Necker Hospital for Sick Children, Paris, France.

8 publications

PubMed DOI Crossref
Autoantibodies neutralizing type I IFNs in patients with fulminant herpes simplex virus hepatitis.
Gervais A, Marchal A, Boucherit S, ..., Casanova JL, Jouanguy E
J. Exp. Med. 223 (3) - [2026-03-02; online 2025-12-05]
PubMed DOI Crossref
Human LY9 governs CD4+ T cell IFN-γ immunity to Mycobacterium tuberculosis.
Ogishi M, Puchan J, Yang R, ..., Boisson-Dupuis S, Casanova JL
Sci Immunol 10 (107) eads7377 [2025-05-30; online 2025-05-30]
PubMed DOI Crossref
Incontinentia pigmenti underlies thymic dysplasia, autoantibodies to type I IFNs, and viral diseases.
Rosain J, Le Voyer T, Liu X, ..., Anderson MS, Casanova JL
J. Exp. Med. 221 (11) - [2024-11-04; online 2024-10-01]
PubMed DOI Crossref
Inherited human RelB deficiency impairs innate and adaptive immunity to infection.
Le Voyer T, Maglorius Renkilaraj MRL, Moriya K, ..., Tangye SG, Puel A
Proc. Natl. Acad. Sci. U.S.A. 121 (37) e2321794121 [2024-09-10; online 2024-09-04]
PubMed DOI Crossref
The immunopathological landscape of human pre-TCRα deficiency: From rare to common variants.
Materna M, Delmonte OM, Bosticardo M, ..., Casanova JL, Béziat V
Science (New York, N.Y.) 383 (6686) eadh4059 [2024-03-00; online 2024-03-01]
PubMed DOI Crossref
Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency.
Le Voyer T, Parent AV, Liu X, ..., Casanova JL, Puel A
Nature 623 (7988) 803-813 [2023-11-00; online 2023-11-08]
PubMed DOI Crossref
Human genetic and immunological determinants of critical COVID-19 pneumonia.
Zhang Q, Bastard P, COVID Human Genetic Effort , Cobat A, Casanova JL
Nature 603 (7902) 587-598 [2022-03-00; online 2022-01-28]
PubMed DOI Crossref
Autoantibodies against type I IFNs in patients with life-threatening COVID-19.
Bastard P, Rosen LB, Zhang Q, ..., Su HC, Casanova JL
Science (New York, N.Y.) 370 (6515) - [2020-10-23; online 2020-09-24]
SciLifeLab Data Centre
Publications 9.5.1