Andrén PE

Family name	Andrén
Given name	Per E
Initials	PE
ORCID	ORCID 0000-0002-4062-7743
Affiliations	Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden. Spatial Mass Spectrometry, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.

46 publications

PubMed DOI Crossref

Chromogranin A and catestatin regulate pancreatic islet homeostasis, endocrine function, and neurotransmitter signaling.

Muntjewerff EM, Epremidze D, Nezhyva M, ..., Mahata SK, Christoffersson G

Commun Biol 8 (1) 1684 [2025-11-26; online 2025-11-26]

Daniel Espes Gustaf Christoffersson SciLifeLab Fellow

PubMed DOI Crossref

The CHCHD2-CHCHD10 protein complex is modulated by mitochondrial dysfunction and alters lipid homeostasis in the mouse brain.

Gerlach J, Pireddu P, Zhang X, ..., Svenningsson P, Filograna R

Cell Death Dis 16 (1) 693 [2025-10-06; online 2025-10-06]

PubMed DOI Crossref

POMC-specific modulation of metabolic and immune pathways via melanocortin-3 receptor signaling.

Nezhyva M, Sandbaumhüter FA, Andrén PE, Jansson ET

Mol Omics 21 (5) 456-463 [2025-09-22; online 2025-09-22]

PubMed DOI Crossref

Cryo-Electron Microscopy Provides Mechanistic Insights into Solution-Dependent Polymorphism and Cross-Aggregation Phenomena of the Human and Rat Islet Amyloid Polypeptides.

Valli D, Ooi SA, Kaya I, ..., Andrén PE, Maj M

Biochemistry 64 (12) 2583-2595 [2025-06-17; online 2025-05-26]

PubMed DOI Crossref

Quantitative Mass Spectrometry Imaging Protocols for Spatially Heterogeneous Samples.

Shariatgorji R, Niehues M, Nilsson A, ..., Svenningsson P, Andrén PE

Anal. Chem. 97 (21) 10957-10961 [2025-06-03; online 2025-05-22]

PubMed DOI Crossref

Preserving Neuronal Chemical Messengers: Heat Stabilization Versus Snap Freezing for Improved MALDI Mass Spectrometry Imaging of Brain Tissues.

Salviati E, Luptáková D, Nilsson A, ..., Roman E, Andrén PE

J. Neurochem. 169 (6) e70122 [2025-06-00; online 2025-06-16]

PubMed DOI Crossref

Enduring modulation of dorsal raphe nuclei regulates (R,S)-ketamine-mediated resilient stress-coping behavior.

Camargo A, Nilsson A, Shariatgorji R, ..., Andren PE, Svenningsson P

Mol. Psychiatry 30 (6) 2504-2516 [2025-06-00; online 2024-11-26]

PubMed DOI Crossref

Met-ID: An Open-Source Software for Comprehensive Annotation of Multiple On-Tissue Chemical Modifications in MALDI-MSI.

Bjärterot P, Nilsson A, Shariatgorji R, ..., Käll L, Andrén PE

Anal. Chem. 97 (16) 9033-9041 [2025-04-29; online 2025-04-20]

Met-ID: An Open-Source Software for Comprehensive Annotation of Multiple On-Tissue Chemical Modifications in MALDI-MSI

Bjärterot P, Nilsson A, Shariatgorji R, ..., Käll L, Andrén PE

- - (-) - [2025-01-27; online 2025-01-27]

PubMed DOI Crossref

Comprehensive Approach for Sequential MALDI-MSI Analysis of Lipids, N-Glycans, and Peptides in Fresh-Frozen Rodent Brain Tissues.

Lee YR, Kaya I, Wik E, ..., Svenningsson P, Andrén PE

Anal. Chem. 97 (2) 1338-1346 [2025-01-21; online 2025-01-09]

Spatial multiomic insights into acute cocaine exposure

Nezhyva M, Shahen-Zoabi S, Kabirova M, ..., Margulis K, Jansson ET

PNAS Nexus 3 (10) - [2024-10-01; online 2024-10-10]

PubMed DOI Crossref

Hydrazide-based reactive matrices for the sensitive detection of aldehydes and ketones by MALDI mass spectrometry imaging.

Lodén H, Schembri LS, Nilsson A, ..., Odell LR, Andrén PE

Chem. Commun. (Camb.) 60 (69) 9238-9241 [2024-08-22; online 2024-08-22]

PubMed DOI Crossref

Applying Spatial Metabolomics To Investigate Age- and Drug-Induced Neurochemical Changes.

Vallianatou T, Angerer TB, Kaya I, ..., Svenningsson P, Andrén PE

ACS Chem Neurosci 15 (15) 2822-2829 [2024-08-07; online 2024-07-29]

PubMed DOI Crossref

Hydrogen production by a fully de novo enzyme.

Berglund S, Bassy C, Kaya I, ..., Magnuson A, Glover SD

Dalton Trans 53 (31) 12905-12916 [2024-08-06; online 2024-08-06]

PubMed DOI Crossref

Regional Changes in Brain Biomolecular Markers in a Collagen-Induced Arthritis Rat Model.

Millen AME, Maluleke TT, Pienaar L, ..., Andrén PE, Baijnath S

Biology (Basel) 13 (7) - [2024-07-10; online 2024-07-10]

PubMed DOI Crossref

Spatial multimodal analysis of transcriptomes and metabolomes in tissues.

Vicari M, Mirzazadeh R, Nilsson A, ..., Andrén PE, Lundeberg J

Nat. Biotechnol. 42 (7) 1046-1050 [2024-07-00; online 2023-09-04]

PubMed DOI Crossref

Rapid Metabolic Profiling of 1 μL Crude Cerebrospinal Fluid by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging Can Differentiate De Novo Parkinson's Disease.

Vallianatou T, Nilsson A, Bjärterot P, ..., Svenningsson P, Andrén PE

Anal. Chem. 95 (50) 18352-18360 [2023-12-19; online 2023-12-07]

PubMed DOI Crossref

Label-Free Quantitative Thermal Proteome Profiling Reveals Target Transcription Factors with Activities Modulated by MC3R Signaling.

Sandbaumhüter FA, Nezhyva M, Andrén PE, Jansson ET

Anal. Chem. 95 (41) 15400-15408 [2023-10-17; online 2023-10-07]

PubMed DOI Crossref

Prosaposin maintains lipid homeostasis in dopamine neurons and counteracts experimental parkinsonism in rodents.

He Y, Kaya I, Shariatgorji R, ..., Andren PE, Svenningsson P

Nat Commun 14 (1) 5804 [2023-09-19; online 2023-09-19]

PubMed DOI Crossref

Spatial lipidomics reveals brain region-specific changes of sulfatides in an experimental MPTP Parkinson's disease primate model.

Kaya I, Nilsson A, Luptáková D, ..., Bezard E, Andrén PE

NPJ Parkinsons Dis 9 (1) 118 [2023-07-26; online 2023-07-26]

PubMed DOI Crossref

On-Tissue Chemical Derivatization for Comprehensive Mapping of Brain Carboxyl and Aldehyde Metabolites by MALDI-MS Imaging.

Kaya I, Schembri LS, Nilsson A, ..., Odell LR, Andrén PE

J. Am. Soc. Mass Spectrom. 34 (5) 836-846 [2023-05-03; online 2023-04-13]

GABA, glucose and insulin orchestrate CD4 + T cells effector functions

Jin Z, Hammoud H, Bhandage A, ..., Kamali-Moghaddam M, Birnir B

- - (-) - [2023-04-20; online 2023-04-20]

PubMed DOI Crossref

Electrochemically Etched Tapered-Tip Stainless-Steel Electrospray-Ionization Emitters for Capillary Electrophoresis-Mass Spectrometry.

Aerts JT, Andrén PE, Jansson ET

J. Proteome Res. 22 (4) 1377-1380 [2023-04-07; online 2023-03-03]

Spatial Multimodal Analysis of Transcriptomes and Metabolomes in Tissues

Vicari M, Mirzazadeh R, Nilsson A, ..., Andrén PE, Lundeberg J

- - (-) - [2023-01-27; online 2023-01-27]

PubMed DOI Crossref

Zero-Degree Celsius Capillary Electrophoresis Electrospray Ionization for Hydrogen Exchange Mass Spectrometry.

Aerts JT, Andrén PE, Jansson ET

Anal. Chem. 95 (2) 1149-1158 [2023-01-17; online 2022-12-22]

PubMed DOI Crossref

Enantioselective CE-MS analysis of ketamine metabolites in urine.

Sandbaumhüter FA, Aerts JT, Theurillat R, ..., Thormann W, Jansson ET

Electrophoresis 44 (1-2) 125-134 [2023-01-00; online 2022-12-09]

PubMed DOI Crossref

The Influence of Plant Stress Hormones and Biotic Elicitors on Cyclotide Production in Viola uliginosa Cell Suspension Cultures.

Slazak B, Jędrzejska A, Badyra B, ..., Andrén PE, Göransson U

Plants (Basel) 11 (14) - [2022-07-19; online 2022-07-19]

PubMed DOI Crossref

Basal ganglia neuropeptides show abnormal processing associated with L-DOPA-induced dyskinesia.

Hulme H, Fridjonsdottir E, Vallianatou T, ..., Bezard E, Andrén PE

NPJ Parkinsons Dis 8 (1) 41 [2022-04-13; online 2022-04-13]

PubMed DOI Crossref

Well-Plate μFASP for Proteomic Analysis of Single Pancreatic Islets.

Sandbaumhüter FA, Nezhyva M, Eriksson O, ..., Andrén PE, Jansson ET

J. Proteome Res. 21 (4) 1167-1174 [2022-04-01; online 2022-03-16]

PubMed DOI Crossref

Method To Visualize the Intratumor Distribution and Impact of Gemcitabine in Pancreatic Ductal Adenocarcinoma by Multimodal Imaging.

Strittmatter N, Richards FM, Race AM, ..., Goodwin RJA, Jodrell DI

Anal. Chem. 94 (3) 1795-1803 [2022-01-25; online 2022-01-10]

PubMed DOI Crossref

Region-Specific and Age-Dependent Multitarget Effects of Acetylcholinesterase Inhibitor Tacrine on Comprehensive Neurotransmitter Systems.

Fridjonsdottir E, Vallianatou T, Mantas I, ..., Svenningsson P, Andrén PE

ACS chemical biology 17 (1) 147-158 [2022-01-21; online 2021-12-21]

PubMed DOI Crossref

Holistic Characterization of a Salmonella Typhimurium Infection Model Using Integrated Molecular Imaging.

Strittmatter N, Kanvatirth P, Inglese P, ..., Goodwin RJA, Mastroeni P

J. Am. Soc. Mass Spectrom. 32 (12) 2791-2802 [2021-12-01; online 2021-11-12]

PubMed DOI Crossref

Neuropharmacokinetic visualization of regional and subregional unbound antipsychotic drug transport across the blood-brain barrier.

Luptáková D, Vallianatou T, Nilsson A, ..., Loryan I, Andrén PE

Mol. Psychiatry 26 (12) 7732-7745 [2021-12-00; online 2021-09-03]

PubMed DOI Crossref

Wide-Ranging Effects on the Brain Proteome in a Transgenic Mouse Model of Alzheimer's Disease Following Treatment with a Brain-Targeting Somatostatin Peptide.

Rofo F, Sandbaumhüter FA, Chourlia A, ..., Jansson ET, Hultqvist G

ACS Chem Neurosci 12 (13) 2529-2541 [2021-07-07; online 2021-06-25]

PubMed DOI Crossref

Spatial visualization of comprehensive brain neurotransmitter systems and neuroactive substances by selective in situ chemical derivatization mass spectrometry imaging.

Shariatgorji R, Nilsson A, Fridjonsdottir E, ..., Odell LR, Andrén PE

Nat Protoc 16 (7) 3298-3321 [2021-07-00; online 2021-06-02]

PubMed DOI Crossref

Integration of Mass Spectrometry Imaging and Machine Learning Visualizes Region-Specific Age-Induced and Drug-Target Metabolic Perturbations in the Brain.

Vallianatou T, Shariatgorji R, Nilsson A, ..., Svenningsson P, Andrén PE

ACS Chem Neurosci 12 (10) 1811-1823 [2021-05-19; online 2021-05-03]

PubMed DOI Crossref

Mass spectrometry imaging identifies abnormally elevated brain l-DOPA levels and extrastriatal monoaminergic dysregulation in l-DOPA-induced dyskinesia.

Fridjonsdottir E, Shariatgorji R, Nilsson A, ..., Bezard E, Andrén PE

Sci Adv 7 (2) - [2021-01-00; online 2021-01-06]

PubMed DOI Crossref

Bromopyrylium Derivatization Facilitates Identification by Mass Spectrometry Imaging of Monoamine Neurotransmitters and Small Molecule Neuroactive Compounds.

Shariatgorji R, Nilsson A, Strittmatter N, ..., Goodwin RJA, Andrén PE

J. Am. Soc. Mass Spectrom. 31 (12) 2553-2557 [2020-12-02; online 2020-07-21]

PubMed DOI Crossref

Cross-validated Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging Quantitation Protocol for a Pharmaceutical Drug and Its Drug-Target Effects in the Brain Using Time-of-Flight and Fourier Transform Ion Cyclotron Resonance Analyzers.

Källback P, Vallianatou T, Nilsson A, ..., Svenningsson P, Andrén PE

Anal. Chem. 92 (21) 14676-14684 [2020-11-03; online 2020-10-21]

PubMed DOI Crossref

Molecular imaging identifies age-related attenuation of acetylcholine in retrosplenial cortex in response to acetylcholinesterase inhibition.

Vallianatou T, Shariatgorji M, Nilsson A, ..., Svenningsson P, Andrén PE

Neuropsychopharmacology 44 (12) 2091-2098 [2019-11-00; online 2019-04-22]

PubMed DOI Crossref

Comprehensive mapping of neurotransmitter networks by MALDI-MS imaging.

Shariatgorji M, Nilsson A, Fridjonsdottir E, ..., Odell LR, Andrén PE

Nat. Methods 16 (10) 1021-1028 [2019-10-00; online 2019-09-23]

PubMed DOI Crossref

α-synuclein-lipoprotein interactions and elevated ApoE level in cerebrospinal fluid from Parkinson's disease patients.

Paslawski W, Zareba-Paslawska J, Zhang X, ..., Andrén PE, Svenningsson P

Proc. Natl. Acad. Sci. U.S.A. 116 (30) 15226-15235 [2019-07-23; online 2019-07-03]

PubMed DOI Crossref

Quantitation of Endogenous Metabolites in Mouse Tumors Using Mass-Spectrometry Imaging.

Swales JG, Dexter A, Hamm G, ..., Critchlow SE, Goodwin RJA

Anal. Chem. 90 (10) 6051-6058 [2018-05-15; online 2018-04-26]

PubMed DOI Crossref

Peptide ion channel toxins from the bootlace worm, the longest animal on Earth.

Jacobsson E, Andersson HS, Strand M, ..., Tytgat J, Göransson U

Sci Rep 8 (1) 4596 [2018-03-22; online 2018-03-22]

PubMed DOI Crossref

A Space Efficient Direct Access Data Compression Approach for Mass Spectrometry Imaging.

Källback P, Nilsson A, Shariatgorji M, Andrén PE

Anal. Chem. 90 (6) 3676-3682 [2018-03-20; online 2018-03-08]

PubMed DOI Crossref

Mass Spectrometry Imaging proves differential absorption profiles of well-characterised permeability markers along the crypt-villus axis.

Nilsson A, Peric A, Strimfors M, ..., Andrén PE, Hilgendorf C

Sci Rep 7 (1) 6352 [2017-07-25; online 2017-07-25]

SciLifeLab Data Centre

Publications 9.5.1