Seal S

Family name	Seal
Given name	Srijit
Initials	S
ORCID	ORCID 0000-0003-2790-8679
Affiliations	Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Rd, Cambridge CB2 1EW, United Kingdom. Imaging Platform, Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02141, United States.

13 publications

Small molecule bioactivity benchmarks are often well-predicted by counting cells

Seal S, Dee W, Shah A, ..., Bender A, Carpenter AE

- - (-) - [2025-04-30; online 2025-04-30]

PubMed DOI Crossref

Author Correction: Cell Painting: a decade of discovery and innovation in cellular imaging.

Seal S, Trapotsi MA, Spjuth O, ..., Bender A, Carpenter AE

Nat. Methods 22 (2) 447 [2025-02-00; online 2024-12-13]

PubMed DOI Crossref

Cell Painting: a decade of discovery and innovation in cellular imaging.

Seal S, Trapotsi MA, Spjuth O, ..., Bender A, Carpenter AE

Nat. Methods 22 (2) 254-268 [2025-02-00; online 2024-12-05]

PubMed DOI Crossref

Improved Detection of Drug-Induced Liver Injury by Integrating Predicted In Vivo and In Vitro Data.

Seal S, Williams D, Hosseini-Gerami L, ..., Spjuth O, Bender A

Chem. Res. Toxicol. 37 (8) 1290-1305 [2024-08-19; online 2024-07-09]

PubMed DOI Crossref

Improved Detection of Drug-Induced Liver Injury by Integrating Predicted in vivo and in vitro Data.

Seal S, Williams DP, Hosseini-Gerami L, ..., Spjuth O, Bender A

bioRxiv - (-) - [2024-06-08; online 2024-06-08]

PubMed DOI Crossref

A Decade in a Systematic Review: The Evolution and Impact of Cell Painting.

Seal S, Trapotsi MA, Spjuth O, ..., Bender A, Carpenter AE

bioRxiv - (-) - [2024-05-07; online 2024-05-07]

PubMed DOI Crossref

From pixels to phenotypes: Integrating image-based profiling with cell health data as BioMorph features improves interpretability.

Seal S, Carreras-Puigvert J, Singh S, ..., Spjuth O, Bender A

Mol. Biol. Cell 35 (3) mr2 [2024-03-01; online 2024-01-03]

PubMed DOI Crossref

Insights into Drug Cardiotoxicity from Biological and Chemical Data: The First Public Classifiers for FDA Drug-Induced Cardiotoxicity Rank.

Seal S, Spjuth O, Hosseini-Gerami L, ..., Bender A, Carpenter AE

J Chem Inf Model 64 (4) 1172-1186 [2024-02-26; online 2024-02-01]

PKSmart: An Open-Source Computational Model to Predict in vivo Pharmacokinetics of Small Molecules

Seal S, Trapotsi MA, Subramanian V, ..., Greene N, Bender A

- - (-) - [2024-02-07; online 2024-02-07]

From Pixels to Phenotypes: Integrating Image-Based Profiling with Cell Health Data Improves Interpretability

Seal S, Carreras-Puigvert J, Carpenter AE, Spjuth O, Bender A

- - (-) - [2023-07-16; online 2023-07-16]

PubMed DOI Crossref

Integrating cell morphology with gene expression and chemical structure to aid mitochondrial toxicity detection.

Seal S, Carreras-Puigvert J, Trapotsi MA, ..., Spjuth O, Bender A

Commun Biol 5 (1) 858 [2022-08-23; online 2022-08-23]

Merging Bioactivity Predictions from Cell Morphology and Chemical Fingerprint Models Using Similarity to Training Data

Seal S, Yang H, Trapotsi MA, ..., Spjuth O, Bender A

- - (-) - [2022-08-15; online 2022-08-15]

Integrating Cell Morphology with Gene Expression and Chemical Structure to Aid Mitochondrial Toxicity Detection

Seal S, Carreras-Puigvert J, Trapotsi MA, ..., Spjuth O, Bender A

- - (-) - [2022-01-07; online 2022-01-07]

SciLifeLab Data Centre

Publications 9.5.1