Zhang SM

Uridine cytidine kinases dictate the therapeutic response of molnupiravir via its bioactivation

Shu H, Sharm S, Alam S, ..., Rudd SG, Zhang SM

- - (-) - [2025-05-14; online 2025-05-14]

Coupling cellular drug-target engagement to downstream pharmacology with CeTEAM.

Valerie NCK, Sanjiv K, Mortusewicz O, ..., Page BDG, Altun M

Nat Commun 15 (1) 10347 [2024-12-06; online 2024-12-06]

Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel

Zhang SM, Paulin CBJ, Michel M, ..., Helleday T, Rudd SG

- - (-) - [2023-01-18; online 2023-01-18]

Coupling cellular drug-target engagement to downstream pharmacology with CeTEAM

Valerie NCK, Sanjiv K, Mortusewicz O, ..., Page BDG, Altun M

- - (-) - [2022-09-19; online 2022-09-19]

Correction: Mutant p53-reactivating compound APR-246 synergizes with asparaginase in inducing growth suppression in acute lymphoblastic leukemia cells.

Ceder S, Eriksson SE, Liang YY, ..., Rudd SG, Wiman KG

Cell Death Dis 13 (8) 672 [2022-08-03; online 2022-08-03]

Mutant p53-reactivating compound APR-246 synergizes with asparaginase in inducing growth suppression in acute lymphoblastic leukemia cells.

Ceder S, Eriksson SE, Liang YY, ..., Rudd SG, Wiman KG

Cell Death Dis 12 (7) 709 [2021-07-15; online 2021-07-15]

Drug synergy scoring using minimal dose response matrices

Mäkelä P, Zhang SM, Rudd SG

- - (-) - [2020-10-31; online 2020-10-31]

Development of a chemical probe against NUDT15.

Zhang SM, Desroses M, Hagenkort A, ..., Stenmark P, Helleday T

Nat. Chem. Biol. 16 (10) 1120-1128 [2020-10-00; online 2020-07-20]

SAMHD1 promotes oncogene-induced replication stress

Zhang SM, Calderón-Montaño JM, Rudd SG

- - (-) - [2020-07-29; online 2020-07-29]