Unlocking protein networks with Predictomes: The SPOC advantage.

Elofsson A

Mol. Cell 85 (6) 1050-1051 [2025-03-20; online 2025-03-22]

In this issue of Molecular Cell, Schmid and Walter present "Predictomes,"1 a machine-learning-based platform that utilizes AlphaFold-Multimer (AF-M) to identify high-confidence protein-protein interactions (PPIs). Their SPOC classifier is better than existing methods at separating true and false interactions.

PubMed 40118037

DOI 10.1016/j.molcel.2025.02.010

Crossref 10.1016/j.molcel.2025.02.010

pii: S1097-2765(25)00141-8


Publications 9.5.1