Publications 2017

1101 publications

Serum apolipoprotein A1 and haptoglobin, in patients with suspected drug-induced liver injury (DILI) as biomarkers of recovery.
Peta V, Tse C, Perazzo H, ..., Drug Induced Liver Injury- Groupe Hospitalier Pitié-Salpêtrière , Drug Induced Liver Group of the Injury Safer and Faster Evidence-based Translation consortium
PLoS ONE 12 (12) e0189436 [2017-12-29; online 2017-12-29]
The interaction landscape between transcription factors and the nucleosome
Zhu F, Farnung L, Kaasinen E, ..., Cramer P, Taipale J
- - (-) - [2017-12-28; online 2017-12-28]
Systematic exploration of multiple drug binding sites.
Bálint M, Jeszenői N, Horváth I, van der Spoel D, Hetényi C
J Cheminform 9 (1) 65 [2017-12-28; online 2017-12-28]
Vascularization and odontode structure of a dorsal ridge spine of Romundina stellina Ørvig 1975.
Jerve A, Qu Q, Sanchez S, Ahlberg PE, Haitina T
PLoS ONE 12 (12) e0189833 [2017-12-27; online 2017-12-27]
Fluidic trapping and optical detection of microparticles with a functional optical fiber
Etcheverry S, Russom A, Laurell F, Margulis W
Opt Express 25 (26) 33657 [2017-12-25; online 2017-12-22]
Atrial Fibrillation Genetic Risk Differentiates Cardioembolic Stroke from other Stroke Subtypes
Pulit SL, Weng LC, McArdle PF, ..., Lee JM, Sheth K
- - (-) - [2017-12-24; online 2017-12-24]
A common missense variant of LILRB5 is associated with statin intolerance and myalgia.
K Siddiqui M, Maroteau C, Veluchamy A, ..., Palmer CNA, PREDICTION-ADR Consortium
Eur. Heart J. 38 (48) 3569-3575 [2017-12-21; online 2017-10-12]
Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.
Flannick J, Fuchsberger C, Mahajan A, ..., Boehnke M, McCarthy MI
Sci Data 4 (-) 170179 [2017-12-19; online 2017-12-19]
On-chip conductometric detection of short DNA sequences via electro-hydrodynamic aggregation.
Venzac B, Diakité ML, Herthnek D, ..., Malaquin L, Viovy JL
Analyst 143 (1) 190-199 [2017-12-18; online 2017-11-25]
RNA sequencing of Stentor cell fragments reveals key processes underlying cellular regeneration
Gustafson HO, Jamy M, Ettema TJG
- - (-) - [2017-12-16; online 2017-12-16]
A chemical screen identifies trifluoperazine as an inhibitor of glioblastoma growth.
Pinheiro T, Otrocka M, Seashore-Ludlow B, ..., Simon A, Kirkham M
Biochem. Biophys. Res. Commun. 494 (3-4) 477-483 [2017-12-16; online 2017-10-21]
Detection of phasic dopamine by D1 and D2 striatal medium spiny neurons.
Yapo C, Nair AG, Clement L, ..., Hellgren Kotaleski J, Vincent P
J. Physiol. (Lond.) 595 (24) 7451-7475 [2017-12-15; online 2017-09-02]
Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4.
Skrott Z, Mistrik M, Andersen KK, ..., Deshaies RJ, Bartek J
Nature 552 (7684) 194-199 [2017-12-14; online 2017-12-06]
Immunological Serum Protein Profiles for Noninvasive Detection of Acute Cellular Rejection After Heart Transplantation.
Sukma Dewi I, Gidlöf O, Hollander Z, ..., McManus BM, Smith JG
J. Am. Coll. Cardiol. 70 (23) 2946-2947 [2017-12-12; online 2017-12-09]
Diagnostic Assessment of Deep Learning Algorithms for Detection of Lymph Node Metastases in Women With Breast Cancer.
Ehteshami Bejnordi B, Veta M, Johannes van Diest P, ..., Racoceanu D, Venâncio R
JAMA 318 (22) 2199-2210 [2017-12-12; online 2017-12-14]
DDLS Fellow Kimmo Kartasalo
Bri2 BRICHOS client specificity and chaperone activity are governed by assembly state.
Chen G, Abelein A, Nilsson HE, ..., Fisahn A, Johansson J
Nat Commun 8 (1) 2081 [2017-12-12; online 2017-12-12]
6S RNA plays a role in recovery from nitrogen depletion in Synechocystis sp. PCC 6803.
Heilmann B, Hakkila K, Georg J, ..., Axmann IM, Dienst D
BMC Microbiol. 17 (1) 229 [2017-12-08; online 2017-12-08]
Genomic and phenotypic characteristics of Swedish C. jejuni water isolates.
Nilsson A, Johansson C, Skarp A, ..., Engstrand L, Rautelin H
PLoS ONE 12 (12) e0189222 [2017-12-07; online 2017-12-07]
A Unique ISR Program Determines Cellular Responses to Chronic Stress.
Guan BJ, van Hoef V, Jobava R, ..., Larsson O, Hatzoglou M
Mol. Cell 68 (5) 885-900.e6 [2017-12-07; online 2017-12-09]
The Intriguing Evolutionary Journey of Enteroinvasive
Pasqua M, Michelacci V, Di Martino ML, ..., Morabito S, Prosseda G
Front Microbiol 8 (-) 2390 [2017-12-05; online 2017-12-05]
Affiliated researcher
The Human Cell Atlas.
Regev A, Teichmann SA, Lander ES, ..., Yosef N, Human Cell Atlas Meeting Participants
Elife 6 (-) - [2017-12-05; online 2017-12-05]
A quantitative model for characterizing the evolutionary history of mammalian gene expression
Chen J, Swofford R, Johnson J, ..., di Palma F, Regev A
- - (-) - [2017-12-04; online 2017-12-04]
A myopic perspective on the future of protein diagnostics
Landegren U, Al-Amin RA, Björkesten J
- - (-) - [2017-12-04; online 2017-12-04]
A New Lineage of Eukaryotes Illuminates Early Mitochondrial Genome Reduction.
Janouškovec J, Tikhonenkov DV, Burki F, ..., Mylnikov AP, Keeling PJ
Curr. Biol. 27 (23) 3717-3724.e5 [2017-12-04; online 2017-11-22]
Affiliated researcher Fabien Burki SciLifeLab Fellow
Trends in GPCR drug discovery: new agents, targets and indications.
Hauser AS, Attwood MM, Rask-Andersen M, Schiöth HB, Gloriam DE
Nat Rev Drug Discov 16 (12) 829-842 [2017-12-00; online 2017-10-27]
PLS3 Deletions Lead to Severe Spinal Osteoporosis and Disturbed Bone Matrix Mineralization.
Kämpe AJ, Costantini A, Levy-Shraga Y, ..., Grasemann C, Mäkitie O
J. Bone Miner. Res. 32 (12) 2394-2404 [2017-12-00; online 2017-09-06]
Loss of Conservation of Graph Centralities in Reverse-engineered Transcriptional Regulatory Networks
Weishaupt H, Johansson P, Engström C, ..., Silvestrov S, Swartling FJ
Methodol Comput Appl Probab 19 (4) 1089-1105 [2017-12-00; online 2017-04-03]
Lansoprazole-sulfide, pharmacokinetics of this promising anti-tuberculous agent.
Mdanda S, Baijnath S, Shobo A, ..., Naicker T, Govender T
Biomed. Chromatogr. 31 (12) - [2017-12-00; online 2017-07-13]
Inflammatory infiltrates in parathyroid tumors.
Haglund F, Hallström BM, Nilsson IL, ..., Juhlin CC, Larsson C
Eur. J. Endocrinol. 177 (6) 445-453 [2017-12-00; online 2017-08-30]
East-West paths to unconventional computing.
Adamatzky A, Akl S, Burgin M, ..., Svozil K, Zenil H
Prog. Biophys. Mol. Biol. 131 (-) 469-493 [2017-12-00; online 2017-08-14]
Cytotoxic T cells in chronic idiopathic neutropenia express restricted antigen receptors.
Mastrodemou S, Stalika E, Vardi A, ..., Papadaki HA, Stamatopoulos K
Leuk. Lymphoma 58 (12) 2926-2933 [2017-12-00; online 2017-05-23]
Complex genomic rearrangement in SPG11 due to a DNA replication-based mechanism.
Baskin B, Kalia LV, Banwell BL, Ray PN, Yoon G
Mov Disord 32 (12) 1792-1794 [2017-12-00; online 2017-10-30]
Cancer as an ecomolecular disease and a neoplastic consortium.
Ramón Y Cajal S, Capdevila C, Hernandez-Losa J, ..., Postovit LM, Topisirovic I
Biochim Biophys Acta Rev Cancer 1868 (2) 484-499 [2017-12-00; online 2017-09-23]
A female Viking warrior confirmed by genomics.
Hedenstierna-Jonson C, Kjellström A, Zachrisson T, ..., Götherström A, Storå J
Am. J. Phys. Anthropol. 164 (4) 853-860 [2017-12-00; online 2017-09-08]
Maternal diabetes and incidence of childhood cancer - a nationwide cohort study and exploratory genetic analysis.
Deleskog A, den Hoed M, Tettamanti G, ..., Feychting M, Brooke HL
Clin Epidemiol 9 (-) 633-642 [2017-11-30; online 2017-11-30]
Epigenetic influences on aging: a longitudinal genome-wide methylation study in old Swedish twins
Wang Y, Karlsson R, Lampa E, ..., Pedersen NL, Hägg S
- - (-) - [2017-11-29; online 2017-11-29]
Structural insights into the enzymatic activity and potential substrate promiscuity of human 3-phosphoglycerate dehydrogenase (PHGDH).
Unterlass JE, Wood RJ, Baslé A, ..., Noble MME, Curtin NJ
Oncotarget 8 (61) 104478-104491 [2017-11-28; online 2017-11-06]
STRT-seq-2i: dual-index 5' single cell and nucleus RNA-seq on an addressable microwell array.
Hochgerner H, Lönnerberg P, Hodge R, ..., Zeisel A, Linnarsson S
Sci Rep 7 (1) 16327 [2017-11-27; online 2017-11-27]
Cohort-specific imputation of gene expression improves prediction of warfarin dose for African Americans.
Gottlieb A, Daneshjou R, DeGorter M, ..., Montgomery SB, Altman RB
Genome Med 9 (1) 98 [2017-11-24; online 2017-11-24]
Mutational and putative neoantigen load predict clinical benefit of adoptive T cell therapy in melanoma.
Lauss M, Donia M, Harbst K, ..., Svane IM, Jönsson G
Nat Commun 8 (1) 1738 [2017-11-23; online 2017-11-23]
Determinism and Contingency Shape Metabolic Complementation in an Endosymbiotic Consortium.
Ponce-de-Leon M, Tamarit D, Calle-Espinosa J, ..., Montero F, Pereto J
Front Microbiol 8 (-) 2290 [2017-11-22; online 2017-11-22]
Author response: The Human Cell Atlas
Regev A, Teichmann SA, Lander ES, ..., Xavier R, Yosef N
- - (-) - [2017-11-20; online 2017-11-20]
Somatic PRDM2 c.4467delA mutations in colorectal cancers control histone methylation and tumor growth.
Pandzic T, Rendo V, Lim J, ..., Lindroth AM, Sjöblom T
Oncotarget 8 (58) 98646-98659 [2017-11-17; online 2017-10-09]
Pro-invasive properties of Snail1 are regulated by sumoylation in response to TGFβ stimulation in cancer.
Gudey SK, Sundar R, Heldin CH, Bergh A, Landström M
Oncotarget 8 (58) 97703-97726 [2017-11-17; online 2017-08-09]
Dog ownership and the risk of cardiovascular disease and death - a nationwide cohort study.
Mubanga M, Byberg L, Nowak C, ..., Ingelsson E, Fall T
Sci Rep 7 (1) 15821 [2017-11-17; online 2017-11-17]
A comprehensive structural, biochemical and biological profiling of the human NUDIX hydrolase family.
Carreras-Puigvert J, Zitnik M, Jemth AS, ..., Zupan B, Helleday T
Nat Commun 8 (1) 1541 [2017-11-16; online 2017-11-16]
Segmentation of the inferior longitudinal fasciculus in the human brain: A white matter dissection and diffusion tensor tractography study.
Latini F, Mårtensson J, Larsson EM, ..., Aldskogius H, Ryttlefors M
Brain Res 1675 (-) 102-115 [2017-11-15; online 2017-09-09]
Interleukin-33 Promotes Recruitment of Microglia/Macrophages in Response to Traumatic Brain Injury.
Wicher G, Wallenquist U, Lei Y, ..., Nilsson G, Forsberg-Nilsson K
J. Neurotrauma 34 (22) 3173-3182 [2017-11-15; online 2017-07-21]
Impact of N-methylation of the substance P 1-7 amide on anti-allodynic effect in mice after peripheral administration.
Skogh A, Lesniak A, Gaugaz FZ, ..., Hallberg M, Sandström A
Eur J Pharm Sci 109 (-) 533-540 [2017-11-15; online 2017-09-05]
An exome sequencing based approach for genome-wide association studies in the dog.
Broeckx BJG, Derrien T, Mottier S, ..., Peelman L, Hitte C
Sci Rep 7 (1) 15680 [2017-11-15; online 2017-11-15]
Simultaneous Mapping and Quantitation of Ribonucleotides in Human Mitochondrial DNA.
Kreisel K, Engqvist MKM, Clausen AR
J Vis Exp - (129) - [2017-11-14; online 2017-11-14]
Human cytomegalovirus and Herpes Simplex type I virus can engage RNA polymerase I for transcription of immediate early genes.
Kostopoulou ON, Wilhelmi V, Raiss S, ..., Bartek J, Söderberg-Naucler C
Oncotarget 8 (57) 96536-96552 [2017-11-14; online 2017-10-29]
Crosstalk between ROR1 and BCR pathways defines novel treatment strategies in mantle cell lymphoma.
Karvonen H, Chiron D, Niininen W, ..., Murumägi A, Ungureanu D
Blood Adv 1 (24) 2257-2268 [2017-11-14; online 2017-11-09]
Female mice lacking Pald1 exhibit endothelial cell apoptosis and emphysema.
Egaña I, Kaito H, Nitzsche A, ..., Hellström M, German Mouse Clinic Consortium
Sci Rep 7 (1) 15453 [2017-11-13; online 2017-11-13]
Archaea and the origin of eukaryotes.
Eme L, Spang A, Lombard J, Stairs CW, Ettema TJG
Nat. Rev. Microbiol. 15 (12) 711-723 [2017-11-10; online 2017-11-11]
Cholesterol Promotes Protein Binding by Affecting Membrane Electrostatics and Solvation Properties.
Doktorova M, Heberle FA, Kingston RL, ..., Vogt VM, Dick RA
Biophys. J. 113 (9) 2004-2015 [2017-11-07; online 2017-11-09]
DDLS Fellow Milka Doktorova
Arteria: An automation system for a sequencing core facility
Dahlberg J, Hermansson J, Sturlaugsson S, Larsson P
- - (-) - [2017-11-06; online 2017-11-06]
Choline transporter mutations in severe congenital myasthenic syndrome disrupt transporter localization.
Wang H, Salter CG, Refai O, ..., Cirak S, Crosby AH
Brain 140 (11) 2838-2850 [2017-11-01; online 2017-11-01]
A 3-way hybrid approach to generate a new high-quality chimpanzee reference genome (Pan_tro_3.0).
Kuderna LFK, Tomlinson C, Hillier LW, ..., Warren WC, Marques-Bonet T
Gigascience 6 (11) 1-6 [2017-11-01; online 2017-11-02]
The role of the skin microbiome in atopic dermatitis: a systematic review.
Bjerre RD, Bandier J, Skov L, Engstrand L, Johansen JD
Br. J. Dermatol. 177 (5) 1272-1278 [2017-11-00; online 2017-11-12]
The complete structure of the small-subunit processome.
Barandun J, Chaker-Margot M, Hunziker M, ..., Chait BT, Klinge S
Nat. Struct. Mol. Biol. 24 (11) 944-953 [2017-11-00; online 2017-09-25]
Jonas Barandun SciLifeLab Fellow
SweGen: a whole-genome data resource of genetic variability in a cross-section of the Swedish population.
Ameur A, Dahlberg J, Olason P, ..., Magnusson PK, Gyllensten U
Eur. J. Hum. Genet. 25 (11) 1253-1260 [2017-11-00; online 2017-08-23]
Species differences in pancreatic binding of DO3A-VS-Cys 40-Exendin4.
Eriksson O, Rosenström U, Selvaraju RK, Eriksson B, Velikyan I
Acta diabetologica 54 (11) 1039-1045 [2017-11-00; online 2017-09-11]
Olof Eriksson SciLifeLab Fellow
Quantitative high-content/high-throughput microscopy analysis of lipid droplets in subject-specific adipogenesis models.
Bombrun M, Gao H, Ranefall P, ..., Arner P, Wählby C
Cytometry A 91 (11) 1068-1077 [2017-11-00; online 2017-10-14]
Medulloblastoma: experimental models and reality.
Neumann JE, Swartling FJ, Schüller U
Acta Neuropathol. 134 (5) 679-689 [2017-11-00; online 2017-07-19]
Intensive care admissions due to poisoning.
Lindqvist E, Edman G, Hollenberg J, ..., Ösby U, Forsberg S
Acta Anaesthesiol Scand 61 (10) 1296-1304 [2017-11-00; online 2017-10-11]
Genotype-based recall to study metabolic effects of genetic variation: a pilot study of PPARG Pro12Ala carriers.
Kamble PG, Gustafsson S, Pereira MJ, ..., Eriksson JW, Ingelsson E
Ups. J. Med. Sci. 122 (4) 234-242 [2017-11-00; online 2018-01-05]
Genetic landscape and deregulated pathways in B-cell lymphoid malignancies.
Rosenquist R, Beà S, Du MQ, Nadel B, Pan-Hammarström Q
J. Intern. Med. 282 (5) 371-394 [2017-11-00; online 2017-06-20]
Enabling the synthesis of medium chain alkanes and 1-alkenes in yeast.
Zhu Z, Zhou YJ, Kang MK, ..., Buijs NA, Nielsen J
Metab. Eng. 44 (-) 81-88 [2017-11-00; online 2017-09-20]
Early stages in the ontogeny of small B-cell lymphomas: genetics and microenvironment.
Ghia P, Nadel B, Sander B, Stamatopoulos K, Stevenson FK
J. Intern. Med. 282 (5) 395-414 [2017-11-00; online 2017-04-10]
Comparison of In Vitro Antileukemic Activity of 4-Hydroperoxyifosfamide and 4-Hydroperoxycyclophosphamide.
Opydo-Chanek M, Śladowska K, Blicharski K, ..., Niemeyer U, Mazur L
Anticancer Res. 37 (11) 6355-6361 [2017-11-00; online 2017-10-25]
An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.
Scott RA, Scott LJ, Mägi R, ..., Prokopenko I, DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium
Diabetes 66 (11) 2888-2902 [2017-11-00; online 2017-05-31]
Altered Protein Composition of Subcutaneous Adipose Tissue in Chronic Kidney Disease.
Gertow J, Ng CZ, Mamede Branca RM, ..., Axelsson J, Fisher RM
Kidney Int Rep 2 (6) 1208-1218 [2017-11-00; online 2017-07-29]
Vitamin and Amino Acid Auxotrophy in Anaerobic Consortia Operating under Methanogenic Conditions.
Hubalek V, Buck M, Tan B, ..., Bertilsson S, Eiler A
mSystems 2 (5) - [2017-10-31; online 2017-10-31]
Thiol-ene-epoxy thermoset for low-temperature bonding to biofunctionalized microarray surfaces.
Zhou XC, Sjöberg R, Druet A, ..., Haraldsson T, Carlborg CF
Lab Chip 17 (21) 3672-3681 [2017-10-25; online 2017-10-05]
Sex influences eQTL effects of SLE and Sjögren's syndrome-associated genetic polymorphisms.
Lindén M, Ramírez Sepúlveda JI, James T, ..., Kockum I, Wahren-Herlenius M
Biol Sex Differ 8 (1) 34 [2017-10-25; online 2017-10-25]
Efficient protein production by yeast requires global tuning of metabolism.
Huang M, Bao J, Hallström BM, Petranovic D, Nielsen J
Nat Commun 8 (1) 1131 [2017-10-25; online 2017-10-25]
Birthweight, Type 2 Diabetes and Cardiovascular Disease: Addressing the Barker Hypothesis with Mendelian randomization
Zanetti D, Tikkanen E, Gustafsson S, ..., Burgess S, Ingelsson E
- - (-) - [2017-10-25; online 2017-10-25]
Tumoral ANXA1 Is a Predictive Marker for Sunitinib Treatment of Renal Cancer Patients.
Niinivirta M, Enblad G, Edqvist PH, ..., Dragomir A, Ullenhag GJ
J. Cancer 8 (19) 3975-3983 [2017-10-23; online 2017-10-23]
Bioconda: A sustainable and comprehensive software distribution for the life sciences
Grüning B, Dale R, Sjödin A, ..., Stephen G, Köster J
- - (-) - [2017-10-21; online 2017-10-21]
RNA velocity in single cells
La Manno G, Soldatov R, Hochgerner H, ..., Linnarsson S, Kharchenko PV
- - (-) - [2017-10-19; online 2017-10-19]
KIT signaling is dispensable for human mast cell progenitor development.
Dahlin JS, Ekoff M, Grootens J, ..., Olsson-Strömberg U, Nilsson G
Blood 130 (16) 1785-1794 [2017-10-19; online 2017-08-08]
Strong binding activity of few transcription factors is a major determinant of open chromatin
Wei B, Jolma A, Sahu B, ..., Taipale M, Taipale J
- - (-) - [2017-10-17; online 2017-10-17]
In situ genotyping of a pooled strain library after characterizing complex phenotypes.
Lawson MJ, Camsund D, Larsson J, ..., Fange D, Elf J
Mol Syst Biol 13 (10) 947 [2017-10-17; online 2017-10-17]
Glioblastoma and glioblastoma stem cells are dependent on functional MTH1.
Pudelko L, Rouhi P, Sanjiv K, ..., Helleday T, Bräutigam L
Oncotarget 8 (49) 84671-84684 [2017-10-17; online 2017-07-20]
FACS sorting and genome amplification of single cells v1
Bergin C, Divne AM
- - (-) - [2017-10-17; online 2017-10-17]
Conservation of differentiation but transformation of initiation in hippocampal neurogenesis
Hochgerner H, Zeisel A, Lönnerberg P, Linnarsson S
- - (-) - [2017-10-17; online 2017-10-17]
Amplification-free, CRISPR-Cas9 Targeted Enrichment and SMRT Sequencing of Repeat-Expansion Disease Causative Genomic Regions
Tsai YC, Greenberg D, Powell J, ..., Korlach J, Clark TA
- - (-) - [2017-10-16; online 2017-10-16]
Controlling adsorption of albumin with hyaluronan on silica surfaces and sulfonated latex particles.
Berts I, Fragneto G, Porcar L, Hellsing MS, Rennie AR
J Colloid Interface Sci 504 (-) 315-324 [2017-10-15; online 2017-05-17]
Novel mutations in Darier disease and association to self-reported disease severity.
Leong IUS, Stuckey A, Ahanian T, Cederlöf M, Wikstrom JD
PLoS ONE 12 (10) e0186356 [2017-10-13; online 2017-10-13]
Lubricin binds cartilage proteins, cartilage oligomeric matrix protein, fibronectin and collagen II at the cartilage surface.
Flowers SA, Zieba A, Örnros J, ..., Kamali-Moghaddam M, Karlsson NG
Sci Rep 7 (1) 13149 [2017-10-13; online 2017-10-13]
Correlations in Scattered X-Ray Laser Pulses Reveal Nanoscale Structural Features of Viruses.
Kurta RP, Donatelli JJ, Yoon CH, ..., Zwart PH, Mancuso AP
Phys. Rev. Lett. 119 (15) 158102 [2017-10-13; online 2017-10-12]
Management of rivaroxaban- or apixaban-associated major bleeding with prothrombin complex concentrates: a cohort study.
Majeed A, Ågren A, Holmström M, ..., Frisk T, Schulman S
Blood 130 (15) 1706-1712 [2017-10-12; online 2017-08-23]
Genetic analysis of over one million people identifies 535 novel loci for blood pressure
Evangelou E, Warren HR, Mosen-Ansorena D, ..., Elliott P, Caulfield MJ
- - (-) - [2017-10-11; online 2017-10-11]
Synthesis of 11C-Labelled Ureas by Palladium(II)-Mediated Oxidative Carbonylation.
Roslin S, Brandt P, Nordeman P, ..., Odell LR, Eriksson J
Molecules 22 (10) - [2017-10-10; online 2017-10-10]
Affiliated researcher
Biological Insights Into Muscular Strength: Genetic Findings in the UK Biobank
Tikkanen E, Gustafsson S, Amar D, ..., Ashley EA, Ingelsson E
- - (-) - [2017-10-10; online 2017-10-10]
Single-Cell Analysis of Human Pancreas Reveals Transcriptional Signatures of Aging and Somatic Mutation Patterns.
Enge M, Arda HE, Mignardi M, ..., Kim SK, Quake SR
Cell 171 (2) 321-330.e14 [2017-10-05; online 2017-09-28]
Chronic Lymphocytic Leukemia Patient Clustering Based on Somatic Hypermutation (SHM) Analysis.
Polychronidou E, Xochelli A, Moschonas P, ..., Stamatopoulos K, Tzovaras D
Springer 988 (-) 127-138 [2017-10-04; online 2017-10-04]
mTOR-sensitive translation: Cleared fog reveals more trees.
Masvidal L, Hulea L, Furic L, Topisirovic I, Larsson O
RNA Biol 14 (10) 1299-1305 [2017-10-03; online 2017-02-10]
Lipid radicals cause light-induced retinal degeneration.
Enoki M, Shinto S, Matsuoka Y, ..., Yamato M, Yamada KI
Chem. Commun. (Camb.) 53 (79) 10922-10925 [2017-10-03; online 2017-09-21]
Mediated Pedestrian Mobility: Walking and the Map App
Laurier E, Brown B, McGregor M
- - (-) 117-134 [2017-10-02; online 2017-10-02]
Gating Pore Currents in Sodium Channels.
Groome JR, Moreau A, Delemotte L
Handb Exp Pharmacol 246 (-) 371-399 [2017-10-02; online 2017-10-02]
Lucie Delemotte SciLifeLab Fellow
The Evolution of Dark Matter in the Mitogenome of Seed Beetles.
Sayadi A, Immonen E, Tellgren-Roth C, Arnqvist G
Genome Biol Evol 9 (10) 2697-2706 [2017-10-01; online 2017-10-20]
Shaping the Tumor Stroma and Sparking Immune Activation by CD40 and 4-1BB Signaling Induced by an Armed Oncolytic Virus.
Eriksson E, Milenova I, Wenthe J, ..., Alemany R, Loskog A
Clin. Cancer Res. 23 (19) 5846-5857 [2017-10-01; online 2017-05-23]
Extensive Type II Muscle Fiber Atrophy in Elderly Female Hip Fracture Patients.
Kramer IF, Snijders T, Smeets JSJ, ..., Poeze M, van Loon LJC
J. Gerontol. A Biol. Sci. Med. Sci. 72 (10) 1369-1375 [2017-10-01; online 2017-03-23]
Validation of risk stratification models in acute myeloid leukemia using sequencing-based molecular profiling.
Wang M, Lindberg J, Klevebring D, ..., Lehmann S, Grönberg H
Leukemia 31 (10) 2029-2036 [2017-10-00; online 2017-02-07]
Spheroid Segmentation Using Multiscale Deep Adversarial Networks
Sadanandan SK, Karlsson J, Wahlby C
- - (-) 36-41 [2017-10-00; online 2017-10-00]
Sll1783, a monooxygenase associated with polysaccharide processing in the unicellular cyanobacterium Synechocystis PCC 6803.
Miranda H, Immerzeel P, Gerber L, ..., Mamedov F, Lindblad P
Physiol Plant 161 (2) 182-195 [2017-10-00; online 2017-06-30]
Reduced cell surface levels of GPI-linked markers in a new case with PIGG loss of function.
Zhao JJ, Halvardson J, Knaus A, ..., Thuresson AC, Feuk L
Hum. Mutat. 38 (10) 1394-1401 [2017-10-00; online 2017-06-12]
Precision systems medicine in urological Tumors – Molecular profiling and functional testing
Saeed K, Ojamies P, Pellinen T, ..., Kallioniemi O, Östling P
Ann Oncol 28 (-) vii2 [2017-10-00; online 2017-10-00]
PLS3 sequencing in childhood-onset primary osteoporosis identifies two novel disease-causing variants.
Kämpe AJ, Costantini A, Mäkitie RE, ..., Jiao H, Mäkitie O
Osteoporos Int 28 (10) 3023-3032 [2017-10-00; online 2017-07-26]
New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals.
Kraja AT, Cook JP, Warren HR, ..., Howson JMM, CHARGE EXOME BP, CHD Exome+, Exome BP, GoT2D:T2DGenes Consortia, The UK Biobank Cardio-Metabolic Traits Consortium Blood Pressure Working Group†
Circ Cardiovasc Genet 10 (5) - [2017-10-00; online 2017-10-17]
Affiliated researcher
Menopausal hormone therapy and cancer risk: An overestimated risk?
Simin J, Tamimi R, Lagergren J, Adami HO, Brusselaers N
Eur. J. Cancer 84 (-) 60-68 [2017-10-00; online 2017-08-04]
Maternal and female fetal testosterone levels are associated with maternal age and gestational weight gain.
Kallak TK, Hellgren C, Skalkidou A, ..., Campbell RE, Sundström Poromaa I
Eur. J. Endocrinol. 177 (4) 379-388 [2017-10-00; online 2017-07-13]
Erika Comasco SciLifeLab Fellow
Immunohistochemical Characterization and Sensitivity to Human Adenovirus Serotypes 3, 5, and 11p of New Cell Lines Derived from Human Diffuse Grade II to IV Gliomas.
Niittykoski M, von Und Zu Fraunberg M, Martikainen M, ..., Jääskeläinen JE, Hinkkanen A
Transl Oncol 10 (5) 772-779 [2017-10-00; online 2017-08-04]
Heparanase confers a growth advantage to differentiating murine embryonic stem cells, and enhances oligodendrocyte formation.
Xiong A, Kundu S, Forsberg M, ..., Li JP, Forsberg-Nilsson K
Matrix Biol. 62 (-) 92-104 [2017-10-00; online 2016-11-23]
H1N1 vaccination in Sjögren's syndrome triggers polyclonal B cell activation and promotes autoantibody production.
Brauner S, Folkersen L, Kvarnström M, ..., Nordmark G, Wahren-Herlenius M
Ann. Rheum. Dis. 76 (10) 1755-1763 [2017-10-00; online 2017-07-31]
Dual Structured Convolutional Neural Network with Feature Augmentation for Quantitative Characterization of Tissue Histology
Valkonen M, Kartasalo K, Liimatainen K, ..., Latonen L, Ruusuvuori P
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DDLS Fellow Kimmo Kartasalo
Dissecting evolution and disease using comparative vertebrate genomics.
Meadows JRS, Lindblad-Toh K
Nat. Rev. Genet. 18 (10) 624-636 [2017-10-00; online 2017-07-24]
Dietary nitrate attenuates renal ischemia-reperfusion injuries by modulation of immune responses and reduction of oxidative stress.
Yang T, Zhang XM, Tarnawski L, ..., Weitzberg E, Carlstrom M
Redox Biol 13 (-) 320-330 [2017-10-00; online 2017-06-09]
Concussion in adolescence and risk of multiple sclerosis.
Montgomery S, Hiyoshi A, Burkill S, ..., Bahmanyar S, Olsson T
Ann. Neurol. 82 (4) 554-561 [2017-10-00; online 2017-09-25]
Breast cancer in young women and prognosis: How important are proliferation markers?
Fredholm H, Magnusson K, Lindström LS, ..., Frisell J, Fredriksson I
Eur. J. Cancer 84 (-) 278-289 [2017-10-00; online 2017-08-29]
Identification of the PAK4 interactome reveals PAK4 phosphorylation of N-WASP and promotion of Arp2/3-dependent actin polymerization.
Zhao M, Spiess M, Johansson HJ, ..., Lehtiö J, Strömblad S
Oncotarget 8 (44) 77061-77074 [2017-09-29; online 2017-08-18]
Mutational signatures reveal the role of RAD52 in p53-independent p21 driven genomic instability
Galanos P, Pappas G, Polyzos A, ..., Bartek J, Gorgoulis VG
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Guidelines for Developing Successful Short Advanced Courses in Systems Medicine and Systems Biology.
Gomez-Cabrero D, Marabita F, Tarazona S, ..., Sabatier P, Tegnér J
Cell Systems 5 (3) 168-175 [2017-09-27; online 2017-08-23]
Ecophysiology of Freshwater Verrucomicrobia Inferred from Metagenome-Assembled Genomes.
He S, Stevens SLR, Chan LK, ..., Malmstrom RR, McMahon KD
mSphere 2 (5) - [2017-09-27; online 2017-09-27]
Autophagy is required for gamete differentiation in the moss Physcomitrella patens.
Sanchez-Vera V, Kenchappa CS, Landberg K, ..., Thelander M, Sundberg E
Autophagy 13 (11) 1939-1951 [2017-09-25; online 2017-09-25]
Affiliated researcher
Antiviral Properties of Chemical Inhibitors of Cellular Anti-Apoptotic Bcl-2 Proteins.
Bulanova D, Ianevski A, Bugai A, ..., Velagapudi V, Kainov DE
Viruses 9 (10) - [2017-09-25; online 2017-09-25]
DESMAN: a new tool for de novo extraction of strains from metagenomes.
Quince C, Delmont TO, Raguideau S, ..., Collins G, Eren AM
Genome Biol. 18 (1) 181 [2017-09-21; online 2017-09-21]
The ribosome assembly gene network is controlled by the feedback regulation of transcription elongation.
Gómez-Herreros F, Margaritis T, Rodríguez-Galán O, ..., Holstege FCP, Chávez S
Nucleic Acids Res. 45 (16) 9302-9318 [2017-09-19; online 2017-06-24]
Affiliated researcher SciLifeLab Fellow
Polarity-Sensitive Probes for Superresolution Stimulated Emission Depletion Microscopy.
Sezgin E, Schneider F, Zilles V, ..., Klymchenko AS, Eggeling C
Biophys. J. 113 (6) 1321-1330 [2017-09-19; online 2017-07-19]
Erdinc Sezgin SciLifeLab Fellow
Tetrahydrobenzothiophene carboxamides: Beyond the kinase domain and into the fatty acid realm.
Llona-Minguez S, Fayezi S, Alihemmati A, ..., Piedrafita FJ, Helleday T
Bioorg. Med. Chem. Lett. 27 (18) 4462-4466 [2017-09-15; online 2017-08-05]
Sex-specific risk of emergency department revisits and early readmission following myocardial infarction.
Lundbäck M, Gasevic D, Rullman E, ..., Carlsson AC, Holzmann MJ
Int. J. Cardiol. 243 (-) 54-58 [2017-09-15; online 2017-05-19]
Predicting accurate contacts in thousands of Pfam domain families using PconsC3.
Michel M, Skwark MJ, Menéndez Hurtado D, Ekeberg M, Elofsson A
Bioinformatics 33 (18) 2859-2866 [2017-09-15; online 2017-05-24]
Heparin antagonizes cisplatin resistance of A2780 ovarian cancer cells by affecting the Wnt signaling pathway.
Pfankuchen DB, Baltes F, Batool T, ..., Schlesinger M, Bendas G
Oncotarget 8 (40) 67553-67566 [2017-09-15; online 2017-06-28]
Data quality of Whole Genome Bisulfite Sequencing on Illumina platforms
Raine A, Liljedahl U, Nordlund J
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The classification of orphans is improved by combining searches in both proteomes and genomes
Basile W, Salvatore M, Elofsson A
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An Algorithmic Information Calculus for Causal Discovery and Reprogramming Systems
Zenil H, Kiani NA, Marabita F, ..., Ball G, Tegnér J
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Impact of network clustering methods on pathway enrichment analysis tools
Castresana M, Ogris C, De Meyer S, Sonnhammer ELL
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Cell-type-specific inhibition of the dendritic plateau potential in striatal spiny projection neurons.
Du K, Wu YW, Lindroos R, ..., Ding JB, Kotaleski JH
Proc. Natl. Acad. Sci. U.S.A. 114 (36) E7612-E7621 [2017-09-05; online 2017-08-21]
Integrative taxonomy reveals too extensive lumping and a new species in the moss genus Amphidium (Bryophyta)
Sim-Sim M, Afonina OM, Almeida T, ..., González-Mancebo JM, Stech M
Systematics and Biodiversity 15 (5) 451-463 [2017-09-03; online 2017-01-19]
TrapSeq: An RNA Sequencing-Based Pipeline for the Identification of Gene-Trap Insertions in Mammalian Cells.
Mayor-Ruiz C, Dominguez O, Fernandez-Capetillo O
J. Mol. Biol. 429 (18) 2780-2789 [2017-09-01; online 2017-08-04]
The Huperzia selago Shoot Tip Transcriptome Sheds New Light on the Evolution of Leaves.
Evkaikina AI, Berke L, Romanova MA, ..., Pawlowski K, Voitsekhovskaja OV
Genome Biol Evol 9 (9) 2444-2460 [2017-09-01; online 2017-09-29]
Reference Intervals for Fecal Calprotectin in Adults Using Two Different Extraction Methods in the Uppsala-SCAPIS Cohort.
Fall T, Mandic-Havelka A, Helmersson-Karlqvist J, Sundstrom J, Larsson A
Clin. Lab. 63 (9) 1493-1496 [2017-09-01; online 2017-09-08]
Affiliated researcher
Quantitative positron emission tomography in brain research.
Heurling K, Leuzy A, Jonasson M, ..., Nordberg A, Lubberink M
Brain Res 1670 (-) 220-234 [2017-09-01; online 2017-06-23]
Predicting allosteric mutants that increase activity of a major antibiotic resistance enzyme.
Latallo MJ, Cortina GA, Faham S, Nakamoto RK, Kasson PM
Chem Sci 8 (9) 6484-6492 [2017-09-01; online 2017-07-19]
E-Science technologies in a workflow for personalized medicine using cancer screening as a case study.
Spjuth O, Karlsson A, Clements M, ..., Litton JE, Palmgren J
J Am Med Inform Assoc 24 (5) 950-957 [2017-09-01; online 2017-04-27]
Chronic Lymphocytic Leukemia with Mutated IGHV4-34 Receptors: Shared and Distinct Immunogenetic Features and Clinical Outcomes.
Xochelli A, Baliakas P, Kavakiotis I, ..., Ghia P, Stamatopoulos K
Clin. Cancer Res. 23 (17) 5292-5301 [2017-09-01; online 2017-05-23]
Artifact reduction in the CSPAD detectors used for LCLS experiments.
Pietrini A, Nettelblad C
J Synchrotron Radiat 24 (Pt 5) 1092-1097 [2017-09-01; online 2017-08-22]
A practical guide to build de-novo assemblies for single tissues of non-model organisms: the example of a Neotropical frog.
Montero-Mendieta S, Grabherr M, Lantz H, ..., Webster MT, Vilà C
PeerJ 5 (-) e3702 [2017-09-01; online 2017-09-01]
Zebularine induces replication-dependent double-strand breaks which are preferentially repaired by homologous recombination.
Orta ML, Pastor N, Burgos-Morón E, ..., Helleday T, Mateos S
DNA Repair (Amst.) 57 (-) 116-124 [2017-09-00; online 2017-07-12]
Vascular sprouts induce local attraction of proangiogenic neutrophils.
Christoffersson G, Lomei J, O'Callaghan P, ..., Engblom S, Phillipson M
J Leukoc Biol 102 (3) 741-751 [2017-09-00; online 2017-06-05]
Gustaf Christoffersson SciLifeLab Fellow
The link between morphology and complement in ocular disease.
Mohlin C, Sandholm K, Ekdahl KN, Nilsson B
Mol. Immunol. 89 (-) 84-99 [2017-09-00; online 2017-06-15]
The Impact of Liposomal Formulations on the Release and Brain Delivery of Methotrexate: An In Vivo Microdialysis Study.
Hu Y, Rip J, Gaillard PJ, de Lange ECM, Hammarlund-Udenaes M
J Pharm Sci 106 (9) 2606-2613 [2017-09-00; online 2017-03-18]
Results after surgical treatment of liver metastases in patients with high-grade gastroenteropancreatic neuroendocrine carcinomas.
Galleberg RB, Knigge U, Tiensuu Janson E, ..., Perren A, Sorbye H
Eur J Surg Oncol 43 (9) 1682-1689 [2017-09-00; online 2017-05-04]
Peptide retention time prediction.
Moruz L, Käll L
Mass Spectrom Rev 36 (5) 615-623 [2017-09-00; online 2016-01-22]
Analytically Sensitive Protein Detection in Microtiter Plates by Proximity Ligation with Rolling Circle Amplification.
Ebai T, Souza de Oliveira FM, Löf L, ..., Landegren U, Kamali-Moghaddam M
Clin. Chem. 63 (9) 1497-1505 [2017-09-00; online 2017-06-30]
A single nucleotide polymorphism in the NCF1 gene leading to reduced oxidative burst is associated with systemic lupus erythematosus.
Olsson LM, Johansson ÅC, Gullstrand B, ..., Bengtsson AA, Holmdahl R
Ann. Rheum. Dis. 76 (9) 1607-1613 [2017-09-00; online 2017-06-12]
Importance of N- and C-terminal residues of substance P 1-7 for alleviating allodynia in mice after peripheral administration.
Skogh A, Lesniak A, Gaugaz FZ, ..., Hallberg M, Sandström A
Eur J Pharm Sci 106 (-) 345-351 [2017-08-30; online 2017-06-03]
A p53-dependent response limits the viability of mammalian haploid cells.
Olbrich T, Mayor-Ruiz C, Vega-Sendino M, ..., Ruiz S, Fernandez-Capetillo O
Proc. Natl. Acad. Sci. U.S.A. 114 (35) 9367-9372 [2017-08-29; online 2017-08-14]
Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide
Satizabal CL, Adams HH, Hibar DP, ..., Seshadri S, Ikram MA
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Cerium oxide nanoparticles inhibit differentiation of neural stem cells.
Gliga AR, Edoff K, Caputo F, ..., Ceccatelli S, Fadeel B
Sci Rep 7 (1) 9284 [2017-08-24; online 2017-08-24]
Clathrin-Independent Endocytosis Suppresses Cancer Cell Blebbing and Invasion.
Holst MR, Vidal-Quadras M, Larsson E, ..., Landström M, Lundmark R
Cell Reports 20 (8) 1893-1905 [2017-08-22; online 2017-08-24]
Antibiotic susceptibility testing in less than 30 min using direct single-cell imaging.
Baltekin Ö, Boucharin A, Tano E, Andersson DI, Elf J
Proc. Natl. Acad. Sci. U.S.A. 114 (34) 9170-9175 [2017-08-22; online 2017-08-08]
Unpacking the Post-Soviet: Political Legacy of the Tartu Semiotic School
Makarychev A, Yatsyk A
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PDGF-BB enhances collagen gel contraction through a PI3K-PLCγ-PKC-cofilin pathway.
Reyhani V, Tsioumpekou M, van Wieringen T, ..., Lennartsson J, Rubin K
Sci Rep 7 (1) 8924 [2017-08-21; online 2017-08-21]
The impact of RNA sequence library construction protocols on transcriptomic profiling of leukemia.
Kumar A, Kankainen M, Parsons A, ..., Mattila P, Heckman CA
BMC Genomics 18 (1) 629 [2017-08-17; online 2017-08-17]
Tea and coffee consumption in relation to DNA methylation in four European cohorts.
Ek WE, Tobi EW, Ahsan M, ..., Johansson Å, Epigenome-Wide Association Study Consortium
Hum. Mol. Genet. 26 (16) 3221-3231 [2017-08-15; online 2017-05-24]
SubCons: a new ensemble method for improved human subcellular localization predictions.
Salvatore M, Warholm P, Shu N, Basile W, Elofsson A
Bioinformatics 33 (16) 2464-2470 [2017-08-15; online 2017-04-14]
ST Pipeline: an automated pipeline for spatial mapping of unique transcripts.
Navarro JF, Sjöstrand J, Salmén F, Lundeberg J, Ståhl PL
Bioinformatics 33 (16) 2591-2593 [2017-08-15; online 2017-04-12]
Real-Time QCM Measurements of Rolling Circle Amplification Products
Madaboosi N, Neumann F, Hernández-Neuta I, ..., Mecea V, Nilsson M
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Comparing tools for gene prioritization
Guala D, Sonnhammer ELL
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Use of Proteomics To Investigate Kidney Function Decline over 5 Years.
Carlsson AC, Ingelsson E, Sundström J, ..., Lind L, Ärnlöv J
Clin J Am Soc Nephrol 12 (8) 1226-1235 [2017-08-07; online 2017-07-21]
Route to 3-Amidino Indoles via Pd(II)-Catalyzed C-H Bond Activation.
Rydfjord J, Skillinghaug B, Brandt P, Odell LR, Larhed M
Org. Lett. 19 (15) 4066-4069 [2017-08-04; online 2017-07-25]
Erratum: Genetic loci associated with heart rate variability and their effects on cardiac disease risk.
Nolte IM, Munoz ML, Tragante V, ..., Snieder H, de Geus EJC
Nat Commun 8 (-) 16140 [2017-08-02; online 2017-08-02]
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Elsässer SJ, Noh KM, Diaz N, Allis CD, Banaszynski LA
Nature 548 (7665) E7-E9 [2017-08-02; online 2017-08-05]
SciLifeLab Fellow Simon Elsässer
Sudden cardiac death among the young in Sweden from 2000 to 2010: an autopsy-based study.
Wisten A, Krantz P, Stattin EL
Europace 19 (8) 1327-1334 [2017-08-01; online 2017-09-07]
Plasma Mannose Levels Are Associated with Incident Type 2 Diabetes and Cardiovascular Disease.
Mardinoglu A, Stančáková A, Lotta LA, ..., Langenberg C, Smith U
Cell Metab. 26 (2) 281-283 [2017-08-01; online 2017-08-03]
Adil Mardinoglu SciLifeLab Fellow
Gene Duplication Leads to Altered Membrane Topology of a Cytochrome P450 Enzyme in Seed Plants.
Renault H, De Marothy M, Jonasson G, ..., von Heijne G, Werck-Reichhart D
Mol. Biol. Evol. 34 (8) 2041-2056 [2017-08-01; online 2017-05-16]
Diverse heterocyclic scaffolds as dCTP pyrophosphatase 1 inhibitors. Part 2: Pyridone- and pyrimidinone-derived systems.
Llona-Minguez S, Häggblad M, Martens U, ..., Scobie M, Helleday T
Bioorg. Med. Chem. Lett. 27 (15) 3219-3225 [2017-08-01; online 2017-06-15]
With me or against me: Tumor suppressor and drug resistance activities of SAMHD1.
Herold N, Rudd SG, Sanjiv K, ..., Henter JI, Schaller T
Exp. Hematol. 52 (-) 32-39 [2017-08-00; online 2017-05-11]
Vimentin deficiency in macrophages induces CD36-mediated inflammation
Håversen L, Ståhlman M, Mattson Hultén L, ..., Levin M, Borén J
Atherosclerosis 263 (-) e87-e88 [2017-08-00; online 2017-08-00]
Adil Mardinoglu SciLifeLab Fellow
Structural pathway of regulated substrate transfer and threading through an Hsp100 disaggregase.
Deville C, Carroni M, Franke KB, ..., Mogk A, Saibil HR
Sci Adv 3 (8) e1701726 [2017-08-00; online 2017-08-04]
Affiliated researcher
Searching for Biosignatures in Exoplanetary Impact Ejecta.
Cataldi G, Brandeker A, Thébault P, ..., Neubeck A, Olofsson G
Astrobiology 17 (8) 721-746 [2017-08-00; online 2017-07-10]
Affiliated researcher
Replication stress, DNA damage signalling, and cytomegalovirus infection in human medulloblastomas.
Bartek J, Fornara O, Merchut-Maya JM, ..., Söderberg Naucler C, Bartkova J
Mol Oncol 11 (8) 945-964 [2017-08-00; online 2017-06-17]
Objective automated quantification of fluorescence signal in histological sections of rat lens.
Talebizadeh N, Hagström NZ, Yu Z, ..., Söderberg P, Wählby C
Cytometry A 91 (8) 815-821 [2017-08-00; online 2017-05-11]
Multiple pathogen biomarker detection using an encoded bead array in droplet PCR.
Periyannan Rajeswari PK, Soderberg LM, Yacoub A, ..., Andersson Svahn H, Joensson HN
J. Microbiol. Methods 139 (-) 22-28 [2017-08-00; online 2017-04-20]
Loss of Chromosome Y in Leukocytes and Major Cardiovascular Events.
Dumanski JP, Sundström J, Forsberg LA
Circ Cardiovasc Genet 10 (4) e001820 [2017-08-00; online 2017-08-05]
Inhibition of Heparanase in Pediatric Brain Tumor Cells Attenuates their Proliferation, Invasive Capacity, and In Vivo Tumor Growth.
Spyrou A, Kundu S, Haseeb L, ..., Vlodavsky I, Forsberg-Nilsson K
Mol. Cancer Ther. 16 (8) 1705-1716 [2017-08-00; online 2017-07-17]
Improvement of myocardial infarction risk prediction via inflammation-associated metabolite biomarkers.
Ward-Caviness CK, Xu T, Aspelund T, ..., Wang-Sattler R, Peters A
Heart 103 (16) 1278-1285 [2017-08-00; online 2017-03-02]
Genotype-covariate interaction effects and the heritability of adult body mass index.
Robinson MR, English G, Moser G, ..., Cesarini D, Visscher PM
Nat. Genet. 49 (8) 1174-1181 [2017-08-00; online 2017-07-10]
Epigenetic Regulation of ZBTB18 Promotes Glioblastoma Progression.
Fedele V, Dai F, Masilamani AP, ..., Bredel M, Carro MS
Mol. Cancer Res. 15 (8) 998-1011 [2017-08-00; online 2017-05-16]
Engineered Cpf1 variants with altered PAM specificities.
Gao L, Cox DBT, Yan WX, ..., Crosetto N, Zhang F
Nat. Biotechnol. 35 (8) 789-792 [2017-08-00; online 2017-06-05]
Domestication rewired gene expression and nucleotide diversity patterns in tomato.
Sauvage C, Rau A, Aichholz C, ..., David J, Glémin S
Plant J. 91 (4) 631-645 [2017-08-00; online 2017-06-12]
Defibrillation before EMS arrival in western Sweden.
Claesson A, Herlitz J, Svensson L, ..., Axelsson C, Bremer A
Am J Emerg Med 35 (8) 1043-1048 [2017-08-00; online 2017-02-16]
Comparison of cellular location and expression of Plakophilin-2 in epidermal cells from nonlesional atopic skin and healthy skin in German shepherd dogs.
Ardesjö-Lundgren B, Tengvall K, Bergvall K, ..., Lindblad-Toh K, Andersson G
Vet. Dermatol. 28 (4) 377-e88 [2017-08-00; online 2017-04-06]
CTCF counter-regulates cardiomyocyte development and maturation programs in the embryonic heart.
Gomez-Velazquez M, Badia-Careaga C, Lechuga-Vieco AV, ..., Gomez-Skarmeta JL, Manzanares M
PLoS Genet 13 (8) e1006985 [2017-08-00; online 2017-08-28]
Affiliated researcher
CKM Glu83Gly Is Associated With Blunted Creatine Kinase Variation, but Not With Myalgia.
Siddiqui MK, Veluchamy A, Maroteau C, ..., Palmer CNA, PREDICTION-ADR Consortium
Circ Cardiovasc Genet 10 (4) - [2017-08-00; online 2017-08-10]
A MUTYH germline mutation is associated with small intestinal neuroendocrine tumors.
Dumanski JP, Rasi C, Björklund P, ..., Hellman P, Tiensuu Janson E
Endocr. Relat. Cancer 24 (8) 427-443 [2017-08-00; online 2017-06-20]
26th Annual Computational Neuroscience Meeting (CNS*2017): Part 2
Rubchinsky LL, Ahn S, Klijn W, ..., Neymotin SA, Antic SD
BMC Neurosci 18 (S1) - [2017-08-00; online 2017-08-18]
Rapid signal enhancement method for nanoprobe-based biosensing.
Dias JT, Svedberg G, Nystrand M, Andersson-Svahn H, Gantelius J
Sci Rep 7 (1) 6837 [2017-07-28; online 2017-07-28]
Vitamin D-deficient mice have more invasive urinary tract infection.
Hertting O, Lüthje P, Sullivan D, Aspenström P, Brauner A
PLoS ONE 12 (7) e0180810 [2017-07-27; online 2017-07-27]
Droplet Barcode Sequencing for targeted linked-read haplotyping of single DNA molecules.
Redin D, Borgström E, He M, ..., Käller M, Ahmadian A
Nucleic Acids Res. 45 (13) e125 [2017-07-27; online 2017-05-20]
Untargeted screening for novel autoantibodies with prognostic value in first-episode psychosis.
Zandian A, Wingård L, Nilsson H, ..., Nilsson P, Persson MAA
Transl Psychiatry 7 (7) e1177 [2017-07-25; online 2017-07-25]
Continuous immunotypes describe human immune variation and predict diverse responses.
Kaczorowski KJ, Shekhar K, Nkulikiyimfura D, ..., Chakraborty AK, Brodin P
Proc. Natl. Acad. Sci. U.S.A. 114 (30) E6097-E6106 [2017-07-25; online 2017-07-10]
Archaeal evolution: The methanogenic roots of Archaea.
Spang A, Ettema TJG
Nat. Microbiol 2 (-) 17109 [2017-07-25; online 2017-07-25]
Novel risk genes for systemic lupus erythematosus predicted by random forest classification.
Almlöf JC, Alexsson A, Imgenberg-Kreuz J, ..., Sandling JK, Syvänen AC
Sci Rep 7 (1) 6236 [2017-07-24; online 2017-07-24]
Effects of Detergent Micelles on Lipid Binding to Proteins in Electrospray Ionization Mass Spectrometry.
Landreh M, Costeira-Paulo J, Gault J, Marklund EG, Robinson CV
Anal. Chem. 89 (14) 7425-7430 [2017-07-18; online 2017-07-03]
Affiliated researcher
De novo active sites for resurrected Precambrian enzymes.
Risso VA, Martinez-Rodriguez S, Candel AM, ..., Gavira JA, Sanchez-Ruiz JM
Nat Commun 8 (-) 16113 [2017-07-18; online 2017-07-18]
Transancestral mapping and genetic load in systemic lupus erythematosus.
Langefeld CD, Ainsworth HC, Cunninghame Graham DS, ..., Gaffney PM, Vyse TJ
Nat Commun 8 (-) 16021 [2017-07-17; online 2017-07-17]
Meta-analysis of exome array data identifies six novel genetic loci for lung function
Jackson VE, Latourelle JC, Wain LV, ..., Tobin MD, London SJ
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High performance micro-flow cytometer based on optical fibres.
Etcheverry S, Faridi A, Ramachandraiah H, ..., Laurell F, Russom A
Sci Rep 7 (1) 5628 [2017-07-17; online 2017-07-17]
Large-scale structure prediction by improved contact predictions and model quality assessment.
Michel M, Menéndez Hurtado D, Uziela K, Elofsson A
Bioinformatics 33 (14) i23-i29 [2017-07-15; online 2017-09-09]
Does antifouling paint select for antibiotic resistance?
Flach CF, Pal C, Svensson CJ, ..., Tysklind M, Larsson DGJ
Sci. Total Environ. 590-591 (-) 461-468 [2017-07-15; online 2017-03-08]
DDLS Fellow Johan Bengtsson-Palme
A TRPV1-to-secretagogin regulatory axis controls pancreatic β-cell survival by modulating protein turnover.
Malenczyk K, Girach F, Szodorai E, ..., Groop L, Harkany T
EMBO J. 36 (14) 2107-2125 [2017-07-14; online 2017-06-21]
Rare copy number variants in array-based comparative genomic hybridization in early-onset skeletal fragility
Costantini A, Skarp S, Kampe A, ..., Lindstrand A, Makitie O
BA - (-) - [2017-07-11; online 2017-07-11]
Y Chromosome Uncovers the Recent Oriental Origin of Modern Stallions.
Wallner B, Palmieri N, Vogl C, ..., Schlötterer C, Brem G
Curr. Biol. 27 (13) 2029-2035.e5 [2017-07-10; online 2017-06-29]
Molecular Mechanisms behind Free Radical Scavengers Function against Oxidative Stress.
Ahmadinejad F, Geir Møller S, Hashemzadeh-Chaleshtori M, Bidkhori G, Jami MS
Antioxidants (Basel) 6 (3) - [2017-07-10; online 2017-07-10]
Anti-citrullinated protein antibodies cause arthritis by cross-reactivity to joint cartilage.
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Lower inflammatory markers in women with antenatal depression brings the M1/M2 balance into focus from a new direction.
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Absolute Quantification of Protein and mRNA Abundances Demonstrate Variability in Gene-Specific Translation Efficiency in Yeast.
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Olof Eriksson SciLifeLab Fellow
Transcriptomics and methylomics of CD4-positive T cells in arsenic-exposed women.
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Halvarsson BM, Wihlborg AK, Ali M, ..., Hansson M, Nilsson B
Blood Adv 1 (10) 619-623 [2017-04-11; online 2017-04-07]
Abhishek Niroula DDLS Fellow
Interplay between periodic stimulation and GABAergic inhibition in striatal network oscillations.
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PLoS ONE 12 (4) e0175135 [2017-04-06; online 2017-04-06]
Genome-wide Analysis of RNA Polymerase II Termination at Protein-Coding Genes.
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Complete Genome Sequences of the Xylose-Fermenting Candida intermedia Strains CBS 141442 and PYCC 4715.
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Affiliated researcher
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Somatic Ephrin Receptor Mutations Are Associated with Metastasis in Primary Colorectal Cancer.
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Teacher Quality and Student Achievement: Evidence from a Sample of Dutch Twins
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Prediction and Prevention of Parasitic Diseases Using a Landscape Genomics Framework.
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Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.
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Improvement of identification methods for honeybee specific Lactic Acid Bacteria; future approaches.
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PLoS ONE 12 (3) e0174614 [2017-03-27; online 2017-03-27]
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Helicobacter pylori eradication in the Swedish population.
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Electrochemical Genetic Profiling of Single Cancer Cells.
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Microbial community assembly and evolution in subseafloor sediment.
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LASSIM - a network inference toolbox for genome-wide mechanistic modeling
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Discovery of circulating proteins associated to knee radiographic osteoarthritis.
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Reducing VEGF-B Signaling Ameliorates Renal Lipotoxicity and Protects against Diabetic Kidney Disease.
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Cell Metab. 25 (3) 713-726 [2017-03-07; online 2017-02-09]
Cell Cycle–Targeted Cancer Therapies
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Antibody Validation by Immunoprecipitation Followed by Mass Spectrometry Analysis.
Persson H, Preger C, Marcon E, Lengqvist J, Gräslund S
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Pateraki I, Andersen-Ranberg J, Jensen NB, ..., Møller BL, Hamberger B
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A hybrid method for the imputation of genomic data in livestock populations.
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Gentle, fast and effective crystal soaking by acoustic dispensing.
Collins PM, Ng JT, Talon R, ..., Pearce NM, von Delft F
Acta Crystallogr D Struct Biol 73 (Pt 3) 246-255 [2017-03-01; online 2017-03-06]
DDLS Fellow Nicholas Pearce
Estrogen Receptor β as a Therapeutic Target in Breast Cancer Stem Cells.
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Vedolizumab as a successful treatment of CTLA-4-associated autoimmune enterocolitis.
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Tracing Cellular Origin of Human Exosomes Using Multiplex Proximity Extension Assays.
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Tp53 gene p72R polymorphism in chronic lymphocytic leukemia: incidence and clinical significance amongst cases with unmutated immunoglobulin receptors.
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The use of a Swedish telephone medical advice service by the elderly - a population-based study.
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T cells in chronic lymphocytic leukemia display dysregulated expression of immune checkpoints and activation markers.
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Haematologica 102 (3) 562-572 [2017-03-00; online 2016-12-07]
Stool frequency is associated with gut microbiota composition.
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Prevalence of autism and attention-deficit-hyperactivity disorder in Down syndrome: a population-based study.
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Phylogenetic analysis of Monascus and new species from honey, pollen and nests of stingless bees.
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Human ROBO1 regulates white matter structure in corpus callosum.
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Human Cytomegalovirus-Encoded Receptor US28 Is Expressed in Renal Allografts and Facilitates Viral Spreading In Vitro.
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CRTAP variants in early-onset osteoporosis and recurrent fractures.
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Biomimetic spinning of artificial spider silk from a chimeric minispidroin.
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104 A mass cytometry (CYTOF) approach to study B cell alterations during baff blockade treatment with belimumab in systemic lupus erythematosus
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05.16 Transcriptome visualisation of the inflamed rheumatoid arthritis joint
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05.01 Protein profiling in plasma reveals molecular subgroups in systemic lupus erythematosus
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Ann Rheum Dis 76 (-) A52 [2017-03-00; online 2017-03-00]
01.15 Type I IFN system activation in newborns exposed to anti-ro/ssa autoantibodies in utero
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Functional genomics analysis of vitamin D effects on CD4+ T cells in vivo in experimental autoimmune encephalomyelitis ‬.
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Coarse-Grained Simulation of Rodlike Higher-Order Quadruplex Structures at Different Salt Concentrations.
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ACS Omega 2 (2) 386-396 [2017-02-28; online 2017-02-03]
Imatinib increases oxygen delivery in extracellular matrix-rich but not in matrix-poor experimental carcinoma.
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Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney
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Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease.
Webb TR, Erdmann J, Stirrups KE, ..., Kathiresan S, Myocardial Infarction Genetics and CARDIoGRAM Exome Consortia Investigators
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RhoA knockout fibroblasts lose tumor-inhibitory capacity in vitro and promote tumor growth in vivo.
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Application of Noncanonical Amino Acids for Protein Labeling in a Genomically Recoded Escherichia coli.
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Comparison of whole genome amplification techniques for human single cell exome sequencing.
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PLoS ONE 12 (2) e0171566 [2017-02-16; online 2017-02-16]
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Nitration of MOG diminishes its encephalitogenicity depending on MHC haplotype.
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Crystal Structure of the Emerging Cancer Target MTHFD2 in Complex with a Substrate-Based Inhibitor.
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Cancer Res. 77 (4) 937-948 [2017-02-15; online 2016-11-29]
The Baltic Sea Virome: Diversity and Transcriptional Activity of DNA and RNA Viruses.
Zeigler Allen L, McCrow JP, Ininbergs K, ..., Bergman B, Venter JC
mSystems 2 (1) - [2017-02-14; online 2017-02-14]
A novel RNA sequencing data analysis method for cell line authentication.
Fasterius E, Raso C, Kennedy S, ..., Uhlén M, Al-Khalili Szigyarto C
PLoS ONE 12 (2) e0171435 [2017-02-13; online 2017-02-13]
Genetic and Functional Study of L-Type Amino Acid Transporter 1 in Schizophrenia.
Comasco E, Vumma R, Toffoletto S, ..., Jönsson EG, Venizelos N
Neuropsychobiology 74 (2) 96-103 [2017-02-11; online 2017-02-11]
Erika Comasco SciLifeLab Fellow
VMCMC: a graphical and statistical analysis tool for Markov chain Monte Carlo traces.
Ali RH, Bark M, Miró J, ..., Abbas RM, Arvestad L
BMC Bioinformatics 18 (1) 97 [2017-02-10; online 2017-02-10]
microRNAs with AAGUGC seed motif constitute an integral part of an oncogenic signaling network.
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Oncogene 36 (6) 731-745 [2017-02-09; online 2016-08-01]
Rare and low-frequency coding variants alter human adult height.
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Molecular composition of organic matter controls methylmercury formation in boreal lakes.
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Nat Commun 8 (-) 14255 [2017-02-09; online 2017-02-09]
Affiliated researcher
Evolutionary and functional data power search for obsessive-compulsive disorder genes
Noh HJ, Tang R, Flannick J, ..., Karlsson EK, Lindblad-Toh K
- - (-) - [2017-02-09; online 2017-02-09]
Meet Our Editorial Board Member
Heldin CH
CCTR 12 (3) 139-140 [2017-02-08; online 2017-02-08]
Generally applicable transcriptome-wide analysis of translational efficiency using anota2seq
Oertlin C, Lorent J, Gandin V, ..., Topisirovic I, Larsson O
- - (-) - [2017-02-08; online 2017-02-08]
Free energy calculations suggest a mechanism for Na+/K+-ATPase ion selectivity
Razavi AM, Delemotte L, Berlin JR, Carnevale V, Voelz VA
- - (-) - [2017-02-07; online 2017-02-07]
Lucie Delemotte SciLifeLab Fellow
EZH2 inhibition in multiple myeloma downregulates myeloma associated oncogenes and upregulates microRNAs with potential tumor suppressor functions.
Alzrigat M, Párraga AA, Agarwal P, ..., Kalushkova A, Jernberg-Wiklund H
Oncotarget 8 (6) 10213-10224 [2017-02-07; online 2017-01-05]
Optitrain: a randomised controlled exercise trial for women with breast cancer undergoing chemotherapy.
Wengström Y, Bolam KA, Mijwel S, ..., Norrbom J, Rundqvist H
BMC Cancer 17 (1) 100 [2017-02-06; online 2017-02-06]
Posttranscriptional Regulation in Adenovirus Infected Cells.
Zhao H, Konzer A, Mi J, ..., Pettersson U, Lind SB
J. Proteome Res. 16 (2) 872-888 [2017-02-03; online 2016-12-13]
A Synthesis of "Dual Warhead" β-Aryl Ethenesulfonyl Fluorides and One-Pot Reaction to β-Sultams.
Chinthakindi PK, Govender KB, Kumar AS, ..., Naicker T, Arvidsson PI
Org. Lett. 19 (3) 480-483 [2017-02-03; online 2017-01-11]
The Human Adrenal Gland Proteome Defined by Transcriptomics and Antibody-Based Profiling.
Bergman J, Botling J, Fagerberg L, ..., Uhlén M, Pontén F
Endocrinology 158 (2) 239-251 [2017-02-01; online 2016-12-03]
Mouse Models of Pediatric Supratentorial High-grade Glioma Reveal How Cell-of-Origin Influences Tumor Development and Phenotype.
Sreedharan S, Maturi NP, Xie Y, ..., Swartling FJ, Uhrbom L
Cancer Res. 77 (3) 802-812 [2017-02-01; online 2016-11-15]
Massive parallel sequencing questions the pathogenic role of missense variants in dilated cardiomyopathy.
Dalin MG, Engström PG, Ivarsson EG, ..., Andersson B, Bergo MO
Int. J. Cardiol. 228 (-) 742-748 [2017-02-01; online 2016-11-09]
Dysregulated fatty acid metabolism in coronary ectasia: An extended lipidomic analysis.
Boles U, Pinto RC, David S, Abdullah AS, Henein MY
Int. J. Cardiol. 228 (-) 303-308 [2017-02-01; online 2016-11-11]
Design, synthesis and in vitro biological evaluation of oligopeptides targeting E. coli type I signal peptidase (LepB).
De Rosa M, Lu L, Zamaratski E, ..., Mowbray SL, Karlén A
Bioorg. Med. Chem. 25 (3) 897-911 [2017-02-01; online 2016-12-07]
Clinical and Immunological Characteristics of Autoimmune Addison Disease: A Nationwide Swedish Multicenter Study.
Dalin F, Nordling Eriksson G, Dahlqvist P, ..., Kämpe O, Bensing S
J. Clin. Endocrinol. Metab. 102 (2) 379-389 [2017-02-01; online 2016-11-22]
Clinical Characterization of Patients With Autosomal Dominant Short Stature due to Aggrecan Mutations.
Gkourogianni A, Andrew M, Tyzinski L, ..., Nilsson O, Dauber A
J. Clin. Endocrinol. Metab. 102 (2) 460-469 [2017-02-01; online 2016-11-22]
Trapping On-Pathway Intermediates for Large Scale Conformational Changes with Coarse-Grained Simulations
Orellana L, Yoluk Ö, Carrillo O, Orozco M, Lindahl E
Biophysical Journal 112 (3) 485a [2017-02-00; online 2017-02-00]
Self-correcting mismatches during high-fidelity DNA replication.
Fernandez-Leiro R, Conrad J, Yang JC, ..., Scheres SH, Lamers MH
Nat. Struct. Mol. Biol. 24 (2) 140-143 [2017-02-00; online 2017-01-09]
Robust, universal biomarker assay to detect senescent cells in biological specimens.
Evangelou K, Lougiakis N, Rizou SV, ..., Bartek J, Gorgoulis VG
Aging Cell 16 (1) 192-197 [2017-02-00; online 2016-11-17]
PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study.
Schmidt AF, Swerdlow DI, Holmes MV, ..., UCLEB consortium , Sattar N
The Lancet Diabetes & Endocrinology 5 (2) 97-105 [2017-02-00; online 2016-11-29]
Opioid precursor protein isoform is targeted to the cell nuclei in the human brain.
Kononenko O, Bazov I, Watanabe H, ..., Yakovleva T, Bakalkin G
Biochim Biophys Acta Gen Subj 1861 (2) 246-255 [2017-02-00; online 2016-11-10]
Mosaicism in health and disease - clones picking up speed.
Forsberg LA, Gisselsson D, Dumanski JP
Nat. Rev. Genet. 18 (2) 128-142 [2017-02-00; online 2016-12-12]
Molecular interrogation of hypothalamic organization reveals distinct dopamine neuronal subtypes.
Romanov RA, Zeisel A, Bakker J, ..., Horvath TL, Harkany T
Nat. Neurosci. 20 (2) 176-188 [2017-02-00; online 2016-12-19]
Metabolic Syndrome Development During Aging with Special Reference to Obesity Without the Metabolic Syndrome.
Roos V, Elmståhl S, Ingelsson E, ..., Ärnlöv J, Lind L
Metab Syndr Relat Disord 15 (1) 36-43 [2017-02-00; online 2016-10-18]
Meta-omic analyses of Baltic Sea cyanobacteria: diversity, community structure and salt acclimation.
Celepli N, Sundh J, Ekman M, ..., Bergman B, Ininbergs K
Environ. Microbiol. 19 (2) 673-686 [2017-02-00; online 2017-01-27]
Mercury Human Exposure in Populations Living Around Lake Tana (Ethiopia).
Habiba G, Abebe G, Bravo AG, ..., Staffan Ǻ, Bishop K
Biol Trace Elem Res 175 (2) 237-243 [2017-02-00; online 2016-06-09]
Dwarfism and Altered Craniofacial Development in Rabbits Is Caused by a 12.1 kb Deletion at the HMGA2 Locus.
Carneiro M, Hu D, Archer J, ..., Rubin CJ, Andersson L
Genetics 205 (2) 955-965 [2017-02-00; online 2016-12-16]
Does Proton Conduction in the Voltage-Gated Proton Channel hH V 1 Involve Grotthus Hopping via Acidic Residues?
Delemotte L, van Keulen S, Roethlisberger U, ..., Carnevale V, Klein ML
Biophysical Journal 112 (3) 163a-164a [2017-02-00; online 2017-02-00]
Lucie Delemotte SciLifeLab Fellow
Colocalisation - the Tale of Co-Occurrence and Correlation
Parmryd I, Adler J
Biophysical Journal 112 (3) 294a [2017-02-00; online 2017-02-00]
Antigen receptor stereotypy in chronic lymphocytic leukemia.
Stamatopoulos K, Agathangelidis A, Rosenquist R, Ghia P
Leukemia 31 (2) 282-291 [2017-02-00; online 2016-11-04]
Genome-wide signatures of genetic variation within and between populations – a comparative perspective
Vijay N, Weissensteiner M, Burri R, ..., Ellegren H, Wolf JBW
- - (-) - [2017-01-31; online 2017-01-31]
High GC Content Causes Orphan Proteins to be Intrinsically Disordered
Basile W, Sachenkova O, Light S, Elofsson A
- - (-) - [2017-01-27; online 2017-01-27]
c-Jun-N-terminal phosphorylation regulates DNMT1 expression and genome wide methylation in gliomas.
Heiland DH, Ferrarese R, Claus R, ..., Nelander S, Carro MS
Oncotarget 8 (4) 6940-6954 [2017-01-24; online 2016-12-31]
Glioblastoma Cell Malignancy and Drug Sensitivity Are Affected by the Cell of Origin.
Jiang Y, Marinescu VD, Xie Y, ..., Nelander S, Uhrbom L
Cell Reports 18 (4) 977-990 [2017-01-24; online 2017-01-26]
Asgard archaea illuminate the origin of eukaryotic cellular complexity.
Zaremba-Niedzwiedzka K, Caceres EF, Saw JH, ..., Spang A, Ettema TJ
Nature 541 (7637) 353-358 [2017-01-19; online 2017-01-11]
Novel genetic loci associated with hippocampal volume.
Hibar DP, Adams HHH, Jahanshad N, ..., Thompson PM, Ikram MA
Nat Commun 8 (-) 13624 [2017-01-18; online 2017-01-18]
Lithium Accumulates in Neurogenic Brain Regions as Revealed by High Resolution Ion Imaging.
Zanni G, Michno W, Di Martino E, ..., Blomgren K, Hanrieder J
Sci Rep 7 (-) 40726 [2017-01-18; online 2017-01-18]
SciLifeLab Fellow Wojciech Michno
Targeted DNA sequencing and in situ mutation analysis using mobile phone microscopy.
Kühnemund M, Wei Q, Darai E, ..., Ozcan A, Nilsson M
Nat Commun 8 (-) 13913 [2017-01-17; online 2017-01-17]
Genome-wide screen of cell-cycle regulators in normal and tumor cells identifies a differential response to nucleosome depletion.
Sokolova M, Turunen M, Mortusewicz O, ..., Helleday T, Taipale J
Cell Cycle 16 (2) 189-199 [2017-01-17; online 2016-12-08]
Ameloblastoma RNA profiling uncovers a distinct non-coding RNA signature.
Davanian H, Balasiddaiah A, Heymann R, ..., Kruger Weiner C, Chen M
Oncotarget 8 (3) 4530-4542 [2017-01-17; online 2016-12-15]
Architecture of the yeast small subunit processome.
Chaker-Margot M, Barandun J, Hunziker M, Klinge S
Science 355 (6321) - [2017-01-13; online 2016-12-15]
Jonas Barandun SciLifeLab Fellow
Rituximab capping triggers intracellular reorganization of B cells
Koller T, Blok S, Santos AM, ..., Sezgin E, Eggeling C
Matters - (-) - [2017-01-12; online 2017-01-12]
Erdinc Sezgin SciLifeLab Fellow
New insights into the GINS complex explain the controversy between existing structural models.
Carroni M, De March M, Medagli B, ..., Patwardhan A, Onesti S
Sci Rep 7 (-) 40188 [2017-01-10; online 2017-01-10]
Affiliated researcher
Identification of a Novel Autoimmune Peptide Epitope of Prostein in Prostate Cancer.
Pin E, Henjes F, Hong MG, ..., Nilsson P, Schwenk JM
J. Proteome Res. 16 (1) 204-216 [2017-01-06; online 2016-10-24]
Antibody Validation in Bioimaging Applications Based on Endogenous Expression of Tagged Proteins.
Skogs M, Stadler C, Schutten R, ..., Uhlén M, Lundberg E
J. Proteome Res. 16 (1) 147-155 [2017-01-06; online 2016-10-26]
Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity.
Wahl S, Drong A, Lehne B, ..., Grallert H, Chambers JC
Nature 541 (7635) 81-86 [2017-01-05; online 2016-12-21]
HieranoiDB: a database of orthologs inferred by Hieranoid.
Kaduk M, Riegler C, Lemp O, Sonnhammer EL
Nucleic Acids Res. 45 (D1) D687-D690 [2017-01-04; online 2016-10-13]
Elasto-inertial microfluidics for bacteria separation from whole blood for sepsis diagnostics.
Faridi MA, Ramachandraiah H, Banerjee I, ..., Zelenin S, Russom A
J Nanobiotechnology 15 (1) 3 [2017-01-04; online 2017-01-04]
DisProt 7.0: a major update of the database of disordered proteins.
Piovesan D, Tabaro F, Mičetić I, ..., Tompa P, Tosatto SC
Nucleic Acids Res. 45 (D1) D219-D227 [2017-01-04; online 2016-11-28]
Corrigendum: DisProt 7.0: a major update of the database of disordered proteins.
Piovesan D, Tabaro F, Mičetić I, ..., Tompa P, Tosatto SC
Nucleic Acids Res. 45 (D1) D1123-D1124 [2017-01-04; online 2016-12-13]
A systematic search strategy identifies cubilin as independent prognostic marker for renal cell carcinoma.
Gremel G, Djureinovic D, Niinivirta M, ..., Stewart GD, Pontén F
BMC Cancer 17 (1) 9 [2017-01-04; online 2017-01-04]
TRIM28 Controls a Gene Regulatory Network Based on Endogenous Retroviruses in Human Neural Progenitor Cells.
Brattås PL, Jönsson ME, Fasching L, ..., Parmar M, Jakobsson J
Cell Reports 18 (1) 1-11 [2017-01-03; online 2017-01-05]
Atropos: specific, sensitive, and speedy trimming of sequencing reads
Didion JP, Martin M, Collins FS
- - (-) - [2017-01-03; online 2017-01-03]
Sex differences in depression during pregnancy and the postpartum period.
Sundström Poromaa I, Comasco E, Georgakis MK, Skalkidou A
J Neurosci Res 95 (1-2) 719-730 [2017-01-02; online 2016-11-22]
Erika Comasco SciLifeLab Fellow
Comprehensive RNA sequencing of healthy human endometrium at two time points of the menstrual cycle.
Sigurgeirsson B, Åmark H, Jemt A, ..., Lundeberg J, Gidlöf S
Biol. Reprod. 96 (1) 24-33 [2017-01-01; online 2017-04-11]
CADEE: Computer-Aided Directed Evolution of Enzymes.
Amrein BA, Steffen-Munsberg F, Szeler I, ..., Kulkarni Y, Kamerlin SC
IUCrJ 4 (Pt 1) 50-64 [2017-01-01; online 2017-01-01]
Why mitochondria need a genome revisited.
Björkholm P, Ernst AM, Hagström E, Andersson SG
FEBS Lett. 591 (1) 65-75 [2017-01-00; online 2016-12-20]
Affiliated researcher
Whole gene duplication of SCN2A and SCN3A is associated with neonatal seizures and a normal intellectual development.
Thuresson AC, Van Buggenhout G, Sheth F, ..., Clayton Smith J, Soussi Zander C
Clin. Genet. 91 (1) 106-110 [2017-01-00; online 2016-06-02]
Transcriptional Dynamics During Human Adipogenesis and Its Link to Adipose Morphology and Distribution.
Ehrlund A, Mejhert N, Björk C, ..., Arner P, Arner E
Diabetes 66 (1) 218-230 [2017-01-00; online 2016-11-01]
Targeting TGF-β Signaling in Cancer.
Colak S, Ten Dijke P
Trends Cancer 3 (1) 56-71 [2017-01-00; online 2017-01-03]
Systemic lupus erythematosus: still a challenge for physicians.
Bengtsson AA, Rönnblom L
J. Intern. Med. 281 (1) 52-64 [2017-01-00; online 2016-06-16]
Region-specific bioconversion of dynorphin neuropeptide detected by in situ histochemistry and MALDI imaging mass spectrometry.
Bivehed E, Strömvall R, Bergquist J, Bakalkin G, Andersson M
Peptides 87 (-) 20-27 [2017-01-00; online 2016-11-10]
Range size heritability and diversification patterns in the liverwort genus Radula.
Patiño J, Wang J, Renner MAM, ..., Shaw AJ, Vanderpoorten A
Mol. Phylogenet. Evol. 106 (-) 73-85 [2017-01-00; online 2016-09-21]
Mutational analysis of protein folding inside the ribosome exit tunnel.
Farías-Rico JA, Goetz SK, Marino J, von Heijne G
FEBS Lett. 591 (1) 155-163 [2017-01-00; online 2016-12-20]
Multispecies genetic structure and hybridization in the Betula genus across Eurasia.
Tsuda Y, Semerikov V, Sebastiani F, Vendramin GG, Lascoux M
Mol. Ecol. 26 (2) 589-605 [2017-01-00; online 2016-12-24]
Medical versus non medical etiology in out-of-hospital cardiac arrest-Changes in outcome in relation to the revised Utstein template.
Claesson A, Djarv T, Nordberg P, ..., Ravn-Fischer A, Stromsoe A
Resuscitation 110 (-) 48-55 [2017-01-00; online 2016-11-05]
Lake bacterioplankton dynamics over diurnal timescales
Grubisic LM, Bertilsson S, Eiler A, ..., Riemann L, Beier S
Freshw Biol 62 (1) 191-204 [2017-01-00; online 2016-12-16]
Kynurenic acid and psychotic symptoms and personality traits in twins with psychiatric morbidity.
Kegel ME, Johansson V, Wetterberg L, ..., Hultman CM, Erhardt S
Psychiatry Res 247 (-) 105-112 [2017-01-00; online 2016-11-16]
Investigating kinship of Neolithic post-LBK human remains from Krusza Zamkowa, Poland using ancient DNA.
Juras A, Chyleński M, Krenz-Niedbała M, ..., Jakobsson M, Dabert M
Forensic Sci Int Genet 26 (-) 30-39 [2017-01-00; online 2016-10-14]
Human immune system variation.
Brodin P, Davis MM
Nat. Rev. Immunol. 17 (1) 21-29 [2017-01-00; online 2016-12-05]
Flow-cytometric screening of aggregation-inhibitors using a fluorescence-assisted intracellular method.
Lindberg H, Sandersjöö L, Meister SW, ..., Löfblom J, Ståhl S
Biotechnol J 12 (1) - [2017-01-00; online 2016-12-01]
First case of human bacteraemia by Catabacter hongkongensis in Scandinavia.
Kaden R, Thelander M, Engstrand L, Herrmann B
New Microbes New Infect 15 (-) 6-8 [2017-01-00; online 2016-10-04]
Expression of possible targets for new proteasome inhibitors in diffuse large B-cell lymphoma.
Delforoush M, Berglund M, Edqvist PH, ..., Gullbo J, Enblad G
Eur. J. Haematol. 98 (1) 52-56 [2017-01-00; online 2016-07-12]
Evolutionary engineering reveals divergent paths when yeast is adapted to different acidic environments.
Fletcher E, Feizi A, Bisschops MMM, ..., Siewers V, Nielsen J
Metab. Eng. 39 (-) 19-28 [2017-01-00; online 2016-11-02]
Environmental Risk Factors for Diabetes Mellitus in Cats.
Öhlund M, Egenvall A, Fall T, ..., Röcklinsberg H, Holst BS
J. Vet. Intern. Med. 31 (1) 29-35 [2017-01-00; online 2016-12-01]
Elevated levels of circulating CDH5 and FABP1 in association with human drug-induced liver injury.
Mikus M, Drobin K, Gry M, ..., Nilsson P, Schuppe-Koistinen I
Liver Int. 37 (1) 132-140 [2017-01-00; online 2016-06-22]
Droplet size influences division of mammalian cell factories in droplet microfluidic cultivation.
Periyannan Rajeswari PK, Joensson HN, Andersson-Svahn H
Electrophoresis 38 (2) 305-310 [2017-01-00; online 2016-09-12]
Different functions of AKT1 and AKT2 in molecular pathways, cell migration and metabolism in colon cancer cells.
Häggblad Sahlberg S, Mortensen AC, Haglöf J, ..., Stenerlöw B, Nestor M
Int. J. Oncol. 50 (1) 5-14 [2017-01-00; online 2016-11-18]
Affiliated researcher
Detection of Candidatus Neoehrlichia mikurensis and Ehrlichia muris in Estonian ticks.
Ivanova A, Geller J, Katargina O, ..., Lundkvist Å, Golovljova I
Ticks Tick Borne Dis 8 (1) 13-17 [2017-01-00; online 2016-08-24]
Deep Fish.
Ishaq O, Sadanandan SK, Wählby C
SLAS Discov 22 (1) 102-107 [2017-01-00; online 2016-09-26]
Cost and clinical outcome of islet transplantation in Norway 2010-2015.
Schive SW, Foss A, Sahraoui A, ..., Mishra V, Scholz H
Clin Transplant 31 (1) - [2017-01-00; online 2016-12-09]
Circulating levels of perfluoroalkyl substances (PFASs) and carotid artery atherosclerosis.
Lind PM, Salihovic S, van Bavel B, Lind L
Environ. Res. 152 (-) 157-164 [2017-01-00; online 2016-10-20]
Both maternal and offspring Elovl2 genotypes determine systemic DHA levels in perinatal mice.
Pauter AM, Trattner S, Gonzalez-Bengtsson A, ..., Dethlefsen O, Jacobsson A
J. Lipid Res. 58 (1) 111-123 [2017-01-00; online 2016-11-18]
Allogeneic Transplantation for Relapsed Waldenström Macroglobulinemia and Lymphoplasmacytic Lymphoma.
Cornell RF, Bachanova V, D'Souza A, ..., Nieto Y, Hari P
Biol Blood Marrow Transplant 23 (1) 60-66 [2017-01-00; online 2016-10-24]
A multi-step peptidolytic cascade for amino acid recovery in chloroplasts.
Teixeira PF, Kmiec B, Branca RM, ..., Lehtiö J, Glaser E
Nat. Chem. Biol. 13 (1) 15-17 [2017-01-00; online 2016-10-31]
Slipdisc: a versatile sample preparation platform for point of care diagnostics
Banerjee I, Salih T, Ramachandraiah H, ..., Karlsson M, Russom A
RSC Adv. 7 (56) 35048-35054 [2017-00-00; online 2017-00-00]
Patients experience of viewing time-lapse sequences: A prospective survey study
Bladh Blomquis A, Samir R, Engstrom AB, ..., Hardarson T, Hreinsson J
Gynecol Reproduct Endocrinol 01 (01) - [2017-00-00; online 2017-00-00]
Morphology and histology of acanthodian fin spines from the late Silurian Ramsåsa E locality, Skåne, Swede
Jerve A, Bremer O, Sanchez S, Ahlberg P
- - (-) - [2017-00-00; online 2017-00-00]
Lignin depolymerization to monophenolic compounds in a flow-through system
Kumaniaev I, Subbotina E, Sävmarker J, ..., Galkin MV, Samec JSM
Green Chem. 19 (24) 5767-5771 [2017-00-00; online 2017-00-00]
Helicobacter pylori
Enroth H, Engstrand L
- - (-) 527-531 [2017-00-00; online 2017-00-00]
Evolution of Resistance to Insecticide in Disease Vectors
Labbé P, David JP, Alout H, ..., Pasteur N, Weill M
- - (-) 313-339 [2017-00-00; online 2017-00-00]
Pascal Milesi SciLifeLab Fellow
Decoding Gene Expression in 2D and 3D
Bombrun M, Ranefall P, Lindblad J, ..., Nilsson M, Wählby C
- - (-) 257-268 [2017-00-00; online 2017-05-19]
Comparing the landcapes of common retroviral insertion sites across tumor models
Weishaupt H, Čančer M, Engström C, Silvestrov S, Swartling FJ
- 1798 (-) 020173 [2017-00-00; online 2017-00-00]
Bone Morphogenetic Proteins in the Initiation and Progression of Breast Cancer
Ren J, ten Dijke P
- - (-) 409-433 [2017-00-00; online 2017-03-16]
Approximations to Algorithmic Probability
Zenil H
- - (-) 1-11 [2017-00-00; online 2017-09-09]
Algorithmic Cognition and the Computational Nature of the Mind
Zenil H, Gauvrit N
- - (-) 1-9 [2017-00-00; online 2017-09-09]

Publications 9.5.1