Publications 2017

782 publications

Serum apolipoprotein A1 and haptoglobin, in patients with suspected drug-induced liver injury (DILI) as biomarkers of recovery.
Peta V, Tse C, Perazzo H, ..., Drug Induced Liver Injury- Groupe Hospitalier Pitié-Salpêtrière , Drug Induced Liver Group of the Injury Safer and Faster Evidence-based Translation consortium
PLoS ONE 12 (12) e0189436 [2017-12-29; online 2017-12-29]
Affiliated researcher
Systematic exploration of multiple drug binding sites.
Bálint M, Jeszenői N, Horváth I, van der Spoel D, Hetényi C
J Cheminform 9 (1) 65 [2017-12-28; online 2017-12-28]
Affiliated researcher
Fluidic trapping and optical detection of microparticles with a functional optical fiber
Etcheverry S, Russom A, Laurell F, Margulis W
Opt Express 25 (26) 33657 [2017-12-25; online 2017-12-22]
Affiliated researcher
A common missense variant of LILRB5 is associated with statin intolerance and myalgia.
K Siddiqui M, Maroteau C, Veluchamy A, ..., Palmer CNA, PREDICTION-ADR Consortium
Eur. Heart J. 38 (48) 3569-3575 [2017-12-21; online 2017-10-12]
Affiliated researcher
Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.
Flannick J, Fuchsberger C, Mahajan A, ..., Boehnke M, McCarthy MI
Sci Data 4 (-) 170179 [2017-12-19; online 2017-12-19]
Affiliated researcher
On-chip conductometric detection of short DNA sequences via electro-hydrodynamic aggregation.
Venzac B, Diakité ML, Herthnek D, ..., Malaquin L, Viovy JL
Analyst 143 (1) 190-199 [2017-12-18; online 2017-11-25]
Affiliated researcher
A chemical screen identifies trifluoperazine as an inhibitor of glioblastoma growth.
Pinheiro T, Otrocka M, Seashore-Ludlow B, ..., Simon A, Kirkham M
Biochem. Biophys. Res. Commun. 494 (3-4) 477-483 [2017-12-16; online 2017-10-21]
Affiliated researcher
Detection of phasic dopamine by D1 and D2 striatal medium spiny neurons.
Yapo C, Nair AG, Clement L, ..., Hellgren Kotaleski J, Vincent P
J. Physiol. (Lond.) 595 (24) 7451-7475 [2017-12-15; online 2017-09-02]
Affiliated researcher
Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4.
Skrott Z, Mistrik M, Andersen KK, ..., Deshaies RJ, Bartek J
Nature 552 (7684) 194-199 [2017-12-14; online 2017-12-06]
Affiliated researcher
Diagnostic Assessment of Deep Learning Algorithms for Detection of Lymph Node Metastases in Women With Breast Cancer.
Ehteshami Bejnordi B, Veta M, Johannes van Diest P, ..., Racoceanu D, Venâncio R
JAMA 318 (22) 2199-2210 [2017-12-12; online 2017-12-14]
DDLS Fellow Kimmo Kartasalo
Bri2 BRICHOS client specificity and chaperone activity are governed by assembly state.
Chen G, Abelein A, Nilsson HE, ..., Fisahn A, Johansson J
Nat Commun 8 (1) 2081 [2017-12-12; online 2017-12-12]
Affiliated researcher
6S RNA plays a role in recovery from nitrogen depletion in Synechocystis sp. PCC 6803.
Heilmann B, Hakkila K, Georg J, ..., Axmann IM, Dienst D
BMC Microbiol. 17 (1) 229 [2017-12-08; online 2017-12-08]
Affiliated researcher
Genomic and phenotypic characteristics of Swedish C. jejuni water isolates.
Nilsson A, Johansson C, Skarp A, ..., Engstrand L, Rautelin H
PLoS ONE 12 (12) e0189222 [2017-12-07; online 2017-12-07]
Affiliated researcher
A Unique ISR Program Determines Cellular Responses to Chronic Stress.
Guan BJ, van Hoef V, Jobava R, ..., Larsson O, Hatzoglou M
Mol. Cell 68 (5) 885-900.e6 [2017-12-07; online 2017-12-09]
Affiliated researcher
The Intriguing Evolutionary Journey of Enteroinvasive
Pasqua M, Michelacci V, Di Martino ML, ..., Morabito S, Prosseda G
Front Microbiol 8 (-) 2390 [2017-12-05; online 2017-12-05]
Affiliated researcher
The Human Cell Atlas.
Regev A, Teichmann SA, Lander ES, ..., Yosef N, Human Cell Atlas Meeting Participants
Elife 6 (-) - [2017-12-05; online 2017-12-05]
Affiliated researcher
A New Lineage of Eukaryotes Illuminates Early Mitochondrial Genome Reduction.
Janouškovec J, Tikhonenkov DV, Burki F, ..., Mylnikov AP, Keeling PJ
Curr. Biol. 27 (23) 3717-3724.e5 [2017-12-04; online 2017-11-22]
Affiliated researcher Fabien Burki SciLifeLab Fellow
Palladium(0)-Catalyzed Carbonylative One-Pot Synthesis of N-Acylguanidines.
Åkerbladh L, Schembri LS, Larhed M, Odell LR
J. Org. Chem. 82 (23) 12520-12529 [2017-12-01; online 2017-10-27]
Affiliated researcher
Trends in GPCR drug discovery: new agents, targets and indications.
Hauser AS, Attwood MM, Rask-Andersen M, Schiöth HB, Gloriam DE
Nat Rev Drug Discov 16 (12) 829-842 [2017-12-00; online 2017-10-27]
Affiliated researcher
PLS3 Deletions Lead to Severe Spinal Osteoporosis and Disturbed Bone Matrix Mineralization.
Kämpe AJ, Costantini A, Levy-Shraga Y, ..., Grasemann C, Mäkitie O
J. Bone Miner. Res. 32 (12) 2394-2404 [2017-12-00; online 2017-09-06]
Affiliated researcher
Loss of Conservation of Graph Centralities in Reverse-engineered Transcriptional Regulatory Networks
Weishaupt H, Johansson P, Engström C, ..., Silvestrov S, Swartling FJ
Methodol Comput Appl Probab 19 (4) 1089-1105 [2017-12-00; online 2017-04-03]
Affiliated researcher
Lansoprazole-sulfide, pharmacokinetics of this promising anti-tuberculous agent.
Mdanda S, Baijnath S, Shobo A, ..., Naicker T, Govender T
Biomed. Chromatogr. 31 (12) - [2017-12-00; online 2017-07-13]
Affiliated researcher
Inflammatory infiltrates in parathyroid tumors.
Haglund F, Hallström BM, Nilsson IL, ..., Juhlin CC, Larsson C
Eur. J. Endocrinol. 177 (6) 445-453 [2017-12-00; online 2017-08-30]
Affiliated researcher
East-West paths to unconventional computing.
Adamatzky A, Akl S, Burgin M, ..., Svozil K, Zenil H
Prog. Biophys. Mol. Biol. 131 (-) 469-493 [2017-12-00; online 2017-08-14]
Affiliated researcher
EPR Oximetry of Cetuximab-Treated Head-and-Neck Tumours in a Mouse Model.
Gustafsson H, Kale A, Dasu A, ..., Edqvist PH, Roberg K
Cell Biochem. Biophys. 75 (3-4) 299-309 [2017-12-00; online 2017-07-29]
Affiliated researcher
Cytotoxic T cells in chronic idiopathic neutropenia express restricted antigen receptors.
Mastrodemou S, Stalika E, Vardi A, ..., Papadaki HA, Stamatopoulos K
Leuk. Lymphoma 58 (12) 2926-2933 [2017-12-00; online 2017-05-23]
Affiliated researcher
Cancer as an ecomolecular disease and a neoplastic consortium.
Ramón Y Cajal S, Capdevila C, Hernandez-Losa J, ..., Postovit LM, Topisirovic I
Biochim Biophys Acta Rev Cancer 1868 (2) 484-499 [2017-12-00; online 2017-09-23]
Affiliated researcher
A female Viking warrior confirmed by genomics.
Hedenstierna-Jonson C, Kjellström A, Zachrisson T, ..., Götherström A, Storå J
Am. J. Phys. Anthropol. 164 (4) 853-860 [2017-12-00; online 2017-09-08]
Affiliated researcher
A short feature vector for image matching: The Log-Polar Magnitude feature descriptor.
Matuszewski DJ, Hast A, Wählby C, Sintorn IM
PLoS ONE 12 (11) e0188496 [2017-11-30; online 2017-11-30]
Affiliated researcher
STRT-seq-2i: dual-index 5' single cell and nucleus RNA-seq on an addressable microwell array.
Hochgerner H, Lönnerberg P, Hodge R, ..., Zeisel A, Linnarsson S
Sci Rep 7 (1) 16327 [2017-11-27; online 2017-11-27]
Affiliated researcher
Cohort-specific imputation of gene expression improves prediction of warfarin dose for African Americans.
Gottlieb A, Daneshjou R, DeGorter M, ..., Montgomery SB, Altman RB
Genome Med 9 (1) 98 [2017-11-24; online 2017-11-24]
Affiliated researcher
Determinism and Contingency Shape Metabolic Complementation in an Endosymbiotic Consortium.
Ponce-de-Leon M, Tamarit D, Calle-Espinosa J, ..., Montero F, Pereto J
Front Microbiol 8 (-) 2290 [2017-11-22; online 2017-11-22]
Affiliated researcher
Dog ownership and the risk of cardiovascular disease and death - a nationwide cohort study.
Mubanga M, Byberg L, Nowak C, ..., Ingelsson E, Fall T
Sci Rep 7 (1) 15821 [2017-11-17; online 2017-11-17]
Affiliated researcher
A comprehensive structural, biochemical and biological profiling of the human NUDIX hydrolase family.
Carreras-Puigvert J, Zitnik M, Jemth AS, ..., Zupan B, Helleday T
Nat Commun 8 (1) 1541 [2017-11-16; online 2017-11-16]
Affiliated researcher
Interleukin-33 Promotes Recruitment of Microglia/Macrophages in Response to Traumatic Brain Injury.
Wicher G, Wallenquist U, Lei Y, ..., Nilsson G, Forsberg-Nilsson K
J. Neurotrauma 34 (22) 3173-3182 [2017-11-15; online 2017-07-21]
Affiliated researcher
An exome sequencing based approach for genome-wide association studies in the dog.
Broeckx BJG, Derrien T, Mottier S, ..., Peelman L, Hitte C
Sci Rep 7 (1) 15680 [2017-11-15; online 2017-11-15]
Affiliated researcher
Systems pathology by multiplexed immunohistochemistry and whole-slide digital image analysis.
Blom S, Paavolainen L, Bychkov D, ..., Kallioniemi O, Pellinen T
Sci Rep 7 (1) 15580 [2017-11-14; online 2017-11-14]
Affiliated researcher
Human cytomegalovirus and Herpes Simplex type I virus can engage RNA polymerase I for transcription of immediate early genes.
Kostopoulou ON, Wilhelmi V, Raiss S, ..., Bartek J, Söderberg-Naucler C
Oncotarget 8 (57) 96536-96552 [2017-11-14; online 2017-10-29]
Affiliated researcher
Female mice lacking Pald1 exhibit endothelial cell apoptosis and emphysema.
Egaña I, Kaito H, Nitzsche A, ..., Hellström M, German Mouse Clinic Consortium
Sci Rep 7 (1) 15453 [2017-11-13; online 2017-11-13]
Affiliated researcher
Archaea and the origin of eukaryotes.
Eme L, Spang A, Lombard J, Stairs CW, Ettema TJG
Nat. Rev. Microbiol. 15 (12) 711-723 [2017-11-10; online 2017-11-11]
Affiliated researcher
Cholesterol Promotes Protein Binding by Affecting Membrane Electrostatics and Solvation Properties.
Doktorova M, Heberle FA, Kingston RL, ..., Vogt VM, Dick RA
Biophys. J. 113 (9) 2004-2015 [2017-11-07; online 2017-11-09]
DDLS Fellow Milka Doktorova
Southern African ancient genomes estimate modern human divergence to 350,000 to 260,000 years ago.
Schlebusch CM, Malmström H, Günther T, ..., Lombard M, Jakobsson M
Science 358 (6363) 652-655 [2017-11-03; online 2017-09-28]
Affiliated researcher
Choline transporter mutations in severe congenital myasthenic syndrome disrupt transporter localization.
Wang H, Salter CG, Refai O, ..., Cirak S, Crosby AH
Brain 140 (11) 2838-2850 [2017-11-01; online 2017-11-01]
Affiliated researcher
The role of the skin microbiome in atopic dermatitis: a systematic review.
Bjerre RD, Bandier J, Skov L, Engstrand L, Johansen JD
Br. J. Dermatol. 177 (5) 1272-1278 [2017-11-00; online 2017-11-12]
Affiliated researcher
The complete structure of the small-subunit processome.
Barandun J, Chaker-Margot M, Hunziker M, ..., Chait BT, Klinge S
Nat. Struct. Mol. Biol. 24 (11) 944-953 [2017-11-00; online 2017-09-25]
Jonas Barandun SciLifeLab Fellow
SweGen: a whole-genome data resource of genetic variability in a cross-section of the Swedish population.
Ameur A, Dahlberg J, Olason P, ..., Magnusson PK, Gyllensten U
Eur. J. Hum. Genet. 25 (11) 1253-1260 [2017-11-00; online 2017-08-23]
Affiliated researcher
Species differences in pancreatic binding of DO3A-VS-Cys 40-Exendin4.
Eriksson O, Rosenström U, Selvaraju RK, Eriksson B, Velikyan I
Acta diabetologica 54 (11) 1039-1045 [2017-11-00; online 2017-09-11]
Olof Eriksson SciLifeLab Fellow
Medulloblastoma: experimental models and reality.
Neumann JE, Swartling FJ, Schüller U
Acta Neuropathol. 134 (5) 679-689 [2017-11-00; online 2017-07-19]
Affiliated researcher
Genetic landscape and deregulated pathways in B-cell lymphoid malignancies.
Rosenquist R, Beà S, Du MQ, Nadel B, Pan-Hammarström Q
J. Intern. Med. 282 (5) 371-394 [2017-11-00; online 2017-06-20]
Affiliated researcher
Enabling the synthesis of medium chain alkanes and 1-alkenes in yeast.
Zhu Z, Zhou YJ, Kang MK, ..., Buijs NA, Nielsen J
Metab. Eng. 44 (-) 81-88 [2017-11-00; online 2017-09-20]
Affiliated researcher
Early stages in the ontogeny of small B-cell lymphomas: genetics and microenvironment.
Ghia P, Nadel B, Sander B, Stamatopoulos K, Stevenson FK
J. Intern. Med. 282 (5) 395-414 [2017-11-00; online 2017-04-10]
Affiliated researcher
Comparison of
Opydo-Chanek M, Śladowska K, Blicharski K, ..., Niemeyer U, Mazur L
Anticancer Res. 37 (11) 6355-6361 [2017-11-00; online 2017-10-25]
Affiliated researcher
An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.
Scott RA, Scott LJ, Mägi R, ..., Prokopenko I, DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium
Diabetes 66 (11) 2888-2902 [2017-11-00; online 2017-05-31]
Affiliated researcher
Thiol-ene-epoxy thermoset for low-temperature bonding to biofunctionalized microarray surfaces.
Zhou XC, Sjöberg R, Druet A, ..., Haraldsson T, Carlborg CF
Lab Chip 17 (21) 3672-3681 [2017-10-25; online 2017-10-05]
Affiliated researcher
Sex influences eQTL effects of SLE and Sjögren's syndrome-associated genetic polymorphisms.
Lindén M, Ramírez Sepúlveda JI, James T, ..., Kockum I, Wahren-Herlenius M
Biol Sex Differ 8 (1) 34 [2017-10-25; online 2017-10-25]
Affiliated researcher
Efficient protein production by yeast requires global tuning of metabolism.
Huang M, Bao J, Hallström BM, Petranovic D, Nielsen J
Nat Commun 8 (1) 1131 [2017-10-25; online 2017-10-25]
Affiliated researcher
Functional reconstruction of a eukaryotic-like E1/E2/(RING) E3 ubiquitylation cascade from an uncultured archaeon.
Hennell James R, Caceres EF, Escasinas A, ..., Ettema TJG, Robinson NP
Nat Commun 8 (1) 1120 [2017-10-24; online 2017-10-24]
Affiliated researcher
Development of a Bacterial Biosensor for Rapid Screening of Yeast p-Coumaric Acid Production.
Siedler S, Khatri NK, Zsohár A, ..., Sommer MOA, Joensson HN
ACS Synth. Biol. 6 (10) 1860-1869 [2017-10-20; online 2017-06-21]
Affiliated researcher
KIT signaling is dispensable for human mast cell progenitor development.
Dahlin JS, Ekoff M, Grootens J, ..., Olsson-Strömberg U, Nilsson G
Blood 130 (16) 1785-1794 [2017-10-19; online 2017-08-08]
Affiliated researcher
In situ genotyping of a pooled strain library after characterizing complex phenotypes.
Lawson MJ, Camsund D, Larsson J, ..., Fange D, Elf J
Mol Syst Biol 13 (10) 947 [2017-10-17; online 2017-10-17]
Affiliated researcher
Glioblastoma and glioblastoma stem cells are dependent on functional MTH1.
Pudelko L, Rouhi P, Sanjiv K, ..., Helleday T, Bräutigam L
Oncotarget 8 (49) 84671-84684 [2017-10-17; online 2017-07-20]
Affiliated researcher
Novel mutations in Darier disease and association to self-reported disease severity.
Leong IUS, Stuckey A, Ahanian T, Cederlöf M, Wikstrom JD
PLoS ONE 12 (10) e0186356 [2017-10-13; online 2017-10-13]
Affiliated researcher
Correlations in Scattered X-Ray Laser Pulses Reveal Nanoscale Structural Features of Viruses.
Kurta RP, Donatelli JJ, Yoon CH, ..., Zwart PH, Mancuso AP
Phys. Rev. Lett. 119 (15) 158102 [2017-10-13; online 2017-10-12]
Affiliated researcher
Synthesis of 11C-Labelled Ureas by Palladium(II)-Mediated Oxidative Carbonylation.
Roslin S, Brandt P, Nordeman P, ..., Odell LR, Eriksson J
Molecules 22 (10) - [2017-10-10; online 2017-10-10]
Affiliated researcher
mTOR-sensitive translation: Cleared fog reveals more trees.
Masvidal L, Hulea L, Furic L, Topisirovic I, Larsson O
RNA Biol 14 (10) 1299-1305 [2017-10-03; online 2017-02-10]
Affiliated researcher
The Evolution of Dark Matter in the Mitogenome of Seed Beetles.
Sayadi A, Immonen E, Tellgren-Roth C, Arnqvist G
Genome Biol Evol 9 (10) 2697-2706 [2017-10-01; online 2017-10-20]
Affiliated researcher
Extensive Type II Muscle Fiber Atrophy in Elderly Female Hip Fracture Patients.
Kramer IF, Snijders T, Smeets JSJ, ..., Poeze M, van Loon LJC
J. Gerontol. A Biol. Sci. Med. Sci. 72 (10) 1369-1375 [2017-10-01; online 2017-03-23]
Affiliated researcher
Validation of risk stratification models in acute myeloid leukemia using sequencing-based molecular profiling.
Wang M, Lindberg J, Klevebring D, ..., Lehmann S, Grönberg H
Leukemia 31 (10) 2029-2036 [2017-10-00; online 2017-02-07]
Affiliated researcher
Synthesis of 4
Åkerbladh L, Chow SY, Odell LR, Larhed M
ChemistryOpen 6 (5) 620-628 [2017-10-00; online 2017-08-16]
Affiliated researcher
Reduced cell surface levels of GPI-linked markers in a new case with PIGG loss of function.
Zhao JJ, Halvardson J, Knaus A, ..., Thuresson AC, Feuk L
Hum. Mutat. 38 (10) 1394-1401 [2017-10-00; online 2017-06-12]
Affiliated researcher
PLS3 sequencing in childhood-onset primary osteoporosis identifies two novel disease-causing variants.
Kämpe AJ, Costantini A, Mäkitie RE, ..., Jiao H, Mäkitie O
Osteoporos Int 28 (10) 3023-3032 [2017-10-00; online 2017-07-26]
Affiliated researcher
New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals.
Kraja AT, Cook JP, Warren HR, ..., Howson JMM, CHARGE EXOME BP, CHD Exome+, Exome BP, GoT2D:T2DGenes Consortia, The UK Biobank Cardio-Metabolic Traits Consortium Blood Pressure Working Group†
Circ Cardiovasc Genet 10 (5) - [2017-10-00; online 2017-10-17]
Affiliated researcher
Menopausal hormone therapy and cancer risk: An overestimated risk?
Simin J, Tamimi R, Lagergren J, Adami HO, Brusselaers N
Eur. J. Cancer 84 (-) 60-68 [2017-10-00; online 2017-08-04]
Affiliated researcher
Maternal and female fetal testosterone levels are associated with maternal age and gestational weight gain.
Kallak TK, Hellgren C, Skalkidou A, ..., Campbell RE, Sundström Poromaa I
Eur. J. Endocrinol. 177 (4) 379-388 [2017-10-00; online 2017-07-13]
Erika Comasco SciLifeLab Fellow
H1N1 vaccination in Sjögren's syndrome triggers polyclonal B cell activation and promotes autoantibody production.
Brauner S, Folkersen L, Kvarnström M, ..., Nordmark G, Wahren-Herlenius M
Ann. Rheum. Dis. 76 (10) 1755-1763 [2017-10-00; online 2017-07-31]
Affiliated researcher
Dynamics and heterogeneity of brain damage in multiple sclerosis.
Kotelnikova E, Kiani NA, Abad E, ..., Garcia-Ojalvo J, Villoslada P
PLoS Comput Biol 13 (10) e1005757 [2017-10-00; online 2017-10-26]
Affiliated researcher
Dual Structured Convolutional Neural Network with Feature Augmentation for Quantitative Characterization of Tissue Histology
Valkonen M, Kartasalo K, Liimatainen K, ..., Latonen L, Ruusuvuori P
- - (-) 27-35 [2017-10-00; online 2017-10-00]
DDLS Fellow Kimmo Kartasalo
Breast cancer in young women and prognosis: How important are proliferation markers?
Fredholm H, Magnusson K, Lindström LS, ..., Frisell J, Fredriksson I
Eur. J. Cancer 84 (-) 278-289 [2017-10-00; online 2017-08-29]
Affiliated researcher
A drug pocket at the lipid bilayer-potassium channel interface.
Ottosson NE, Silverå Ejneby M, Wu X, ..., Lindahl E, Elinder F
Sci Adv 3 (10) e1701099 [2017-10-00; online 2017-10-25]
Affiliated researcher
Kinetics of dCas9 target search in
Jones DL, Leroy P, Unoson C, ..., Lawson MJ, Elf J
Science 357 (6358) 1420-1424 [2017-09-29; online 2017-09-28]
Affiliated researcher
Ecophysiology of Freshwater Verrucomicrobia Inferred from Metagenome-Assembled Genomes.
He S, Stevens SLR, Chan LK, ..., Malmstrom RR, McMahon KD
mSphere 2 (5) - [2017-09-27; online 2017-09-27]
Affiliated researcher
Autophagy is required for gamete differentiation in the moss Physcomitrella patens.
Sanchez-Vera V, Kenchappa CS, Landberg K, ..., Thelander M, Sundberg E
Autophagy 13 (11) 1939-1951 [2017-09-25; online 2017-09-25]
Affiliated researcher
Antiviral Properties of Chemical Inhibitors of Cellular Anti-Apoptotic Bcl-2 Proteins.
Bulanova D, Ianevski A, Bugai A, ..., Velagapudi V, Kainov DE
Viruses 9 (10) - [2017-09-25; online 2017-09-25]
Affiliated researcher
DESMAN: a new tool for de novo extraction of strains from metagenomes.
Quince C, Delmont TO, Raguideau S, ..., Collins G, Eren AM
Genome Biol. 18 (1) 181 [2017-09-21; online 2017-09-21]
Affiliated researcher
Polarity-Sensitive Probes for Superresolution Stimulated Emission Depletion Microscopy.
Sezgin E, Schneider F, Zilles V, ..., Klymchenko AS, Eggeling C
Biophys. J. 113 (6) 1321-1330 [2017-09-19; online 2017-07-19]
Erdinc Sezgin SciLifeLab Fellow
Tetrahydrobenzothiophene carboxamides: Beyond the kinase domain and into the fatty acid realm.
Llona-Minguez S, Fayezi S, Alihemmati A, ..., Piedrafita FJ, Helleday T
Bioorg. Med. Chem. Lett. 27 (18) 4462-4466 [2017-09-15; online 2017-08-05]
Affiliated researcher
Predicting accurate contacts in thousands of Pfam domain families using PconsC3.
Michel M, Skwark MJ, Menéndez Hurtado D, Ekeberg M, Elofsson A
Bioinformatics 33 (18) 2859-2866 [2017-09-15; online 2017-05-24]
Affiliated researcher
Heparin antagonizes cisplatin resistance of A2780 ovarian cancer cells by affecting the Wnt signaling pathway.
Pfankuchen DB, Baltes F, Batool T, ..., Schlesinger M, Bendas G
Oncotarget 8 (40) 67553-67566 [2017-09-15; online 2017-06-28]
Affiliated researcher
Mass Cytometry Identifies Distinct Lung CD4
Kaiser Y, Lakshmikanth T, Chen Y, ..., Achour A, Grunewald J
Front Immunol 8 (-) 1130 [2017-09-12; online 2017-09-12]
Affiliated researcher
Integrative taxonomy reveals too extensive lumping and a new species in the moss genus Amphidium (Bryophyta)
Sim-Sim M, Afonina OM, Almeida T, ..., González-Mancebo JM, Stech M
Systematics and Biodiversity 15 (5) 451-463 [2017-09-03; online 2017-01-19]
Affiliated researcher
Trap
Mayor-Ruiz C, Dominguez O, Fernandez-Capetillo O
J. Mol. Biol. 429 (18) 2780-2789 [2017-09-01; online 2017-08-04]
Affiliated researcher
The Huperzia selago Shoot Tip Transcriptome Sheds New Light on the Evolution of Leaves.
Evkaikina AI, Berke L, Romanova MA, ..., Pawlowski K, Voitsekhovskaja OV
Genome Biol Evol 9 (9) 2444-2460 [2017-09-01; online 2017-09-29]
Affiliated researcher
Reference Intervals for Fecal Calprotectin in Adults Using Two Different Extraction Methods in the Uppsala-SCAPIS Cohort.
Fall T, Mandic-Havelka A, Helmersson-Karlqvist J, Sundstrom J, Larsson A
Clin. Lab. 63 (9) 1493-1496 [2017-09-01; online 2017-09-08]
Affiliated researcher
Predicting allosteric mutants that increase activity of a major antibiotic resistance enzyme.
Latallo MJ, Cortina GA, Faham S, Nakamoto RK, Kasson PM
Chem Sci 8 (9) 6484-6492 [2017-09-01; online 2017-07-19]
Affiliated researcher
Multifocus structured illumination microscopy for fast volumetric super-resolution imaging.
Abrahamsson S, Blom H, Agostinho A, ..., Heintzmann R, Brismar H
Biomed Opt Express 8 (9) 4135-4140 [2017-09-01; online 2017-08-17]
Affiliated researcher
Genome-wide identification of Grainy head targets in
Yao L, Wang S, Westholm JO, ..., Lai EC, Samakovlis C
Development 144 (17) 3145-3155 [2017-09-01; online 2017-07-31]
Affiliated researcher
A practical guide to build
Montero-Mendieta S, Grabherr M, Lantz H, ..., Webster MT, Vilà C
PeerJ 5 (-) e3702 [2017-09-01; online 2017-09-01]
Affiliated researcher
Vascular sprouts induce local attraction of proangiogenic neutrophils.
Christoffersson G, Lomei J, O'Callaghan P, ..., Engblom S, Phillipson M
J Leukoc Biol 102 (3) 741-751 [2017-09-00; online 2017-06-05]
Gustaf Christoffersson SciLifeLab Fellow
The relative contribution of DNA methylation and genetic variants on protein biomarkers for human diseases.
Ahsan M, Ek WE, Rask-Andersen M, ..., Gyllensten U, Johansson Å
PLoS Genet 13 (9) e1007005 [2017-09-00; online 2017-09-15]
Affiliated researcher
Peptide retention time prediction.
Moruz L, Käll L
Mass Spectrom Rev 36 (5) 615-623 [2017-09-00; online 2016-01-22]
Affiliated researcher
Analytically Sensitive Protein Detection in Microtiter Plates by Proximity Ligation with Rolling Circle Amplification.
Ebai T, Souza de Oliveira FM, Löf L, ..., Landegren U, Kamali-Moghaddam M
Clin. Chem. 63 (9) 1497-1505 [2017-09-00; online 2017-06-30]
Affiliated researcher
Gearing up to handle the mosaic nature of life in the quest for orthologs.
Forslund K, Pereira C, Capella-Gutierrez S, ..., Dessimoz C, Lewis S
Bioinformatics - (-) - [2017-08-30; online 2017-08-30]
Affiliated researcher
A p53-dependent response limits the viability of mammalian haploid cells.
Olbrich T, Mayor-Ruiz C, Vega-Sendino M, ..., Ruiz S, Fernandez-Capetillo O
Proc. Natl. Acad. Sci. U.S.A. 114 (35) 9367-9372 [2017-08-29; online 2017-08-14]
Affiliated researcher
Cerium oxide nanoparticles inhibit differentiation of neural stem cells.
Gliga AR, Edoff K, Caputo F, ..., Ceccatelli S, Fadeel B
Sci Rep 7 (1) 9284 [2017-08-24; online 2017-08-24]
Affiliated researcher
Clathrin-Independent Endocytosis Suppresses Cancer Cell Blebbing and Invasion.
Holst MR, Vidal-Quadras M, Larsson E, ..., Landström M, Lundmark R
Cell Reports 20 (8) 1893-1905 [2017-08-22; online 2017-08-24]
Affiliated researcher
PDGF-BB enhances collagen gel contraction through a PI3K-PLCγ-PKC-cofilin pathway.
Reyhani V, Tsioumpekou M, van Wieringen T, ..., Lennartsson J, Rubin K
Sci Rep 7 (1) 8924 [2017-08-21; online 2017-08-21]
Affiliated researcher
Tea and coffee consumption in relation to DNA methylation in four European cohorts.
Ek WE, Tobi EW, Ahsan M, ..., Johansson Å, Epigenome-Wide Association Study Consortium
Hum. Mol. Genet. 26 (16) 3221-3231 [2017-08-15; online 2017-05-24]
Affiliated researcher
SubCons: a new ensemble method for improved human subcellular localization predictions.
Salvatore M, Warholm P, Shu N, Basile W, Elofsson A
Bioinformatics 33 (16) 2464-2470 [2017-08-15; online 2017-04-14]
Affiliated researcher
ST Pipeline: an automated pipeline for spatial mapping of unique transcripts.
Navarro JF, Sjöstrand J, Salmén F, Lundeberg J, Ståhl PL
Bioinformatics 33 (16) 2591-2593 [2017-08-15; online 2017-04-12]
Affiliated researcher
Automated Training of Deep Convolutional Neural Networks for Cell Segmentation.
Sadanandan SK, Ranefall P, Le Guyader S, Wählby C
Sci Rep 7 (1) 7860 [2017-08-10; online 2017-08-10]
Affiliated researcher
Long-term follow-up in primary Sjögren's syndrome reveals differences in clinical presentation between female and male patients.
Ramírez Sepúlveda JI, Kvarnström M, Eriksson P, ..., Nordmark G, Wahren-Herlenius M
Biol Sex Differ 8 (1) 25 [2017-08-08; online 2017-08-08]
Affiliated researcher
Use of Proteomics To Investigate Kidney Function Decline over 5 Years.
Carlsson AC, Ingelsson E, Sundström J, ..., Lind L, Ärnlöv J
Clin J Am Soc Nephrol 12 (8) 1226-1235 [2017-08-07; online 2017-07-21]
Affiliated researcher
Route to 3-Amidino Indoles via Pd(II)-Catalyzed C-H Bond Activation.
Rydfjord J, Skillinghaug B, Brandt P, Odell LR, Larhed M
Org. Lett. 19 (15) 4066-4069 [2017-08-04; online 2017-07-25]
Affiliated researcher
Enzyme Architecture: Modeling the Operation of a Hydrophobic Clamp in Catalysis by Triosephosphate Isomerase.
Kulkarni YS, Liao Q, Petrović D, ..., Richard JP, Kamerlin SCL
J. Am. Chem. Soc. 139 (30) 10514-10525 [2017-08-02; online 2017-07-19]
Affiliated researcher
Elsässer et al. reply.
Elsässer SJ, Noh KM, Diaz N, Allis CD, Banaszynski LA
Nature 548 (7665) E7-E9 [2017-08-02; online 2017-08-05]
SciLifeLab Fellow Simon Elsässer
Plasma Mannose Levels Are Associated with Incident Type 2 Diabetes and Cardiovascular Disease.
Mardinoglu A, Stančáková A, Lotta LA, ..., Langenberg C, Smith U
Cell Metab. 26 (2) 281-283 [2017-08-01; online 2017-08-03]
Adil Mardinoglu SciLifeLab Fellow
Gene Duplication Leads to Altered Membrane Topology of a Cytochrome P450 Enzyme in Seed Plants.
Renault H, De Marothy M, Jonasson G, ..., von Heijne G, Werck-Reichhart D
Mol. Biol. Evol. 34 (8) 2041-2056 [2017-08-01; online 2017-05-16]
Affiliated researcher
With me or against me: Tumor suppressor and drug resistance activities of SAMHD1.
Herold N, Rudd SG, Sanjiv K, ..., Henter JI, Schaller T
Exp. Hematol. 52 (-) 32-39 [2017-08-00; online 2017-05-11]
Affiliated researcher
Vimentin deficiency in macrophages induces CD36-mediated inflammation
Håversen L, Ståhlman M, Mattson Hultén L, ..., Levin M, Borén J
Atherosclerosis 263 (-) e87-e88 [2017-08-00; online 2017-08-00]
Adil Mardinoglu SciLifeLab Fellow
Structural pathway of regulated substrate transfer and threading through an Hsp100 disaggregase.
Deville C, Carroni M, Franke KB, ..., Mogk A, Saibil HR
Sci Adv 3 (8) e1701726 [2017-08-00; online 2017-08-04]
Affiliated researcher
Searching for Biosignatures in Exoplanetary Impact Ejecta.
Cataldi G, Brandeker A, Thébault P, ..., Neubeck A, Olofsson G
Astrobiology 17 (8) 721-746 [2017-08-00; online 2017-07-10]
Affiliated researcher
Replication stress, DNA damage signalling, and cytomegalovirus infection in human medulloblastomas.
Bartek J, Fornara O, Merchut-Maya JM, ..., Söderberg Naucler C, Bartkova J
Mol Oncol 11 (8) 945-964 [2017-08-00; online 2017-06-17]
Affiliated researcher
Objective automated quantification of fluorescence signal in histological sections of rat lens.
Talebizadeh N, Hagström NZ, Yu Z, ..., Söderberg P, Wählby C
Cytometry A 91 (8) 815-821 [2017-08-00; online 2017-05-11]
Affiliated researcher
Northeast African genomic variation shaped by the continuity of indigenous groups and Eurasian migrations.
Hollfelder N, Schlebusch CM, Günther T, ..., Hassan HY, Jakobsson M
PLoS Genet 13 (8) e1006976 [2017-08-00; online 2017-08-24]
Affiliated researcher
Multiple pathogen biomarker detection using an encoded bead array in droplet PCR.
Periyannan Rajeswari PK, Soderberg LM, Yacoub A, ..., Andersson Svahn H, Joensson HN
J. Microbiol. Methods 139 (-) 22-28 [2017-08-00; online 2017-04-20]
Affiliated researcher
Inhibition of Heparanase in Pediatric Brain Tumor Cells Attenuates their Proliferation, Invasive Capacity, and
Spyrou A, Kundu S, Haseeb L, ..., Vlodavsky I, Forsberg-Nilsson K
Mol. Cancer Ther. 16 (8) 1705-1716 [2017-08-00; online 2017-07-17]
Affiliated researcher
Improvement of myocardial infarction risk prediction via inflammation-associated metabolite biomarkers.
Ward-Caviness CK, Xu T, Aspelund T, ..., Wang-Sattler R, Peters A
Heart 103 (16) 1278-1285 [2017-08-00; online 2017-03-02]
Affiliated researcher
Genotype-covariate interaction effects and the heritability of adult body mass index.
Robinson MR, English G, Moser G, ..., Cesarini D, Visscher PM
Nat. Genet. 49 (8) 1174-1181 [2017-08-00; online 2017-07-10]
Affiliated researcher
Epigenetic Regulation of ZBTB18 Promotes Glioblastoma Progression.
Fedele V, Dai F, Masilamani AP, ..., Bredel M, Carro MS
Mol. Cancer Res. 15 (8) 998-1011 [2017-08-00; online 2017-05-16]
Affiliated researcher
Engineered Cpf1 variants with altered PAM specificities.
Gao L, Cox DBT, Yan WX, ..., Crosetto N, Zhang F
Nat. Biotechnol. 35 (8) 789-792 [2017-08-00; online 2017-06-05]
Affiliated researcher
Domestication rewired gene expression and nucleotide diversity patterns in tomato.
Sauvage C, Rau A, Aichholz C, ..., David J, Glémin S
Plant J. 91 (4) 631-645 [2017-08-00; online 2017-06-12]
Affiliated researcher
Childhood adiposity and risk of type 1 diabetes: A Mendelian randomization study.
Censin JC, Nowak C, Cooper N, ..., Todd JA, Fall T
PLoS Med. 14 (8) e1002362 [2017-08-00; online 2017-08-01]
Affiliated researcher
CTCF counter-regulates cardiomyocyte development and maturation programs in the embryonic heart.
Gomez-Velazquez M, Badia-Careaga C, Lechuga-Vieco AV, ..., Gomez-Skarmeta JL, Manzanares M
PLoS Genet 13 (8) e1006985 [2017-08-00; online 2017-08-28]
Affiliated researcher
CKM Glu83Gly Is Associated With Blunted Creatine Kinase Variation, but Not With Myalgia.
Siddiqui MK, Veluchamy A, Maroteau C, ..., Palmer CNA, PREDICTION-ADR Consortium
Circ Cardiovasc Genet 10 (4) - [2017-08-00; online 2017-08-10]
Affiliated researcher
A
Dumanski JP, Rasi C, Björklund P, ..., Hellman P, Tiensuu Janson E
Endocr. Relat. Cancer 24 (8) 427-443 [2017-08-00; online 2017-06-20]
Affiliated researcher
Rapid signal enhancement method for nanoprobe-based biosensing.
Dias JT, Svedberg G, Nystrand M, Andersson-Svahn H, Gantelius J
Sci Rep 7 (1) 6837 [2017-07-28; online 2017-07-28]
Affiliated researcher
Vitamin D-deficient mice have more invasive urinary tract infection.
Hertting O, Lüthje P, Sullivan D, Aspenström P, Brauner A
PLoS ONE 12 (7) e0180810 [2017-07-27; online 2017-07-27]
Affiliated researcher
Droplet Barcode Sequencing for targeted linked-read haplotyping of single DNA molecules.
Redin D, Borgström E, He M, ..., Käller M, Ahmadian A
Nucleic Acids Res. 45 (13) e125 [2017-07-27; online 2017-05-20]
Affiliated researcher
Untargeted screening for novel autoantibodies with prognostic value in first-episode psychosis.
Zandian A, Wingård L, Nilsson H, ..., Nilsson P, Persson MAA
Transl Psychiatry 7 (7) e1177 [2017-07-25; online 2017-07-25]
Affiliated researcher
Continuous immunotypes describe human immune variation and predict diverse responses.
Kaczorowski KJ, Shekhar K, Nkulikiyimfura D, ..., Chakraborty AK, Brodin P
Proc. Natl. Acad. Sci. U.S.A. 114 (30) E6097-E6106 [2017-07-25; online 2017-07-10]
Affiliated researcher
Novel risk genes for systemic lupus erythematosus predicted by random forest classification.
Almlöf JC, Alexsson A, Imgenberg-Kreuz J, ..., Sandling JK, Syvänen AC
Sci Rep 7 (1) 6236 [2017-07-24; online 2017-07-24]
Affiliated researcher
Effects of Detergent Micelles on Lipid Binding to Proteins in Electrospray Ionization Mass Spectrometry.
Landreh M, Costeira-Paulo J, Gault J, Marklund EG, Robinson CV
Anal. Chem. 89 (14) 7425-7430 [2017-07-18; online 2017-07-03]
Affiliated researcher
De novo active sites for resurrected Precambrian enzymes.
Risso VA, Martinez-Rodriguez S, Candel AM, ..., Gavira JA, Sanchez-Ruiz JM
Nat Commun 8 (-) 16113 [2017-07-18; online 2017-07-18]
Affiliated researcher
Transancestral mapping and genetic load in systemic lupus erythematosus.
Langefeld CD, Ainsworth HC, Cunninghame Graham DS, ..., Gaffney PM, Vyse TJ
Nat Commun 8 (-) 16021 [2017-07-17; online 2017-07-17]
Affiliated researcher
High performance micro-flow cytometer based on optical fibres.
Etcheverry S, Faridi A, Ramachandraiah H, ..., Laurell F, Russom A
Sci Rep 7 (1) 5628 [2017-07-17; online 2017-07-17]
Affiliated researcher
Does antifouling paint select for antibiotic resistance?
Flach CF, Pal C, Svensson CJ, ..., Tysklind M, Larsson DGJ
Sci. Total Environ. 590-591 (-) 461-468 [2017-07-15; online 2017-03-08]
DDLS Fellow Johan Bengtsson-Palme
ATM/Wip1 activities at chromatin control Plk1 re-activation to determine G2 checkpoint duration.
Jaiswal H, Benada J, Müllers E, ..., Macurek L, Lindqvist A
EMBO J. 36 (14) 2161-2176 [2017-07-14; online 2017-06-12]
Affiliated researcher
A TRPV1-to-secretagogin regulatory axis controls pancreatic β-cell survival by modulating protein turnover.
Malenczyk K, Girach F, Szodorai E, ..., Groop L, Harkany T
EMBO J. 36 (14) 2107-2125 [2017-07-14; online 2017-06-21]
Affiliated researcher
Y Chromosome Uncovers the Recent Oriental Origin of Modern Stallions.
Wallner B, Palmieri N, Vogl C, ..., Schlötterer C, Brem G
Curr. Biol. 27 (13) 2029-2035.e5 [2017-07-10; online 2017-06-29]
Affiliated researcher
Polyplex Evolution: Understanding Biology, Optimizing Performance.
Hall A, Lächelt U, Bartek J, Wagner E, Moghimi SM
Mol. Ther. 25 (7) 1476-1490 [2017-07-05; online 2017-03-06]
Affiliated researcher
Analysis of IAV Replication and Co-infection Dynamics by a Versatile RNA Viral Genome Labeling Method.
Dou D, Hernández-Neuta I, Wang H, ..., Nilsson M, Daniels R
Cell Reports 20 (1) 251-263 [2017-07-05; online 2017-07-07]
Affiliated researcher
SCENERY: a web application for (causal) network reconstruction from cytometry data.
Papoutsoglou G, Athineou G, Lagani V, ..., Tegnér J, Tsamardinos I
Nucleic Acids Res. 45 (W1) W270-W275 [2017-07-03; online 2017-05-20]
Affiliated researcher
Mineral Type Structures Soil Microbial Communities
Ahmed E, Hugerth LW, Logue JB, ..., Andersson AF, Holmström SJM
Geomicrobiology Journal 34 (6) 538-545 [2017-07-03; online 2016-11-22]
Affiliated researcher DDLS Fellow Luisa Hugerth
Structure-metabolism-relationships in the microsomal clearance of piperazin-1-ylpyridazines.
Llona-Minguez S, Ghassemian A, Baranczewski P, ..., Scobie M, Helleday T
Med. Chem. Commun. 8 (7) 1553-1560 [2017-07-01; online 2017-07-04]
Affiliated researcher
Dog Exposure During the First Year of Life and Type 1 Diabetes in Childhood.
Wernroth ML, Svennblad B, Fall K, ..., Almqvist C, Fall T
JAMA Pediatr 171 (7) 663-669 [2017-07-01; online 2017-05-02]
Affiliated researcher
Toward molecular imaging of the free fatty acid receptor 1.
Hellström-Lindahl E, Åberg O, Ericsson C, ..., Skrtic S, Eriksson O
Acta diabetologica 54 (7) 663-668 [2017-07-00; online 2017-04-13]
Olof Eriksson SciLifeLab Fellow
Stability of Proteins in Dried Blood Spot Biobanks.
Björkesten J, Enroth S, Shen Q, ..., Kamali-Moghaddam M, Landegren U
Mol. Cell Proteomics 16 (7) 1286-1296 [2017-07-00; online 2017-05-13]
Affiliated researcher
Numerous Ontogenetic Roads to Mantle Cell Lymphoma: Immunogenetic and Immunohistochemical Evidence.
Pouliou E, Xochelli A, Kanellis G, ..., Stamatopoulos K, Papadaki T
Am. J. Pathol. 187 (7) 1454-1458 [2017-07-00; online 2017-04-28]
Affiliated researcher
Low-algorithmic-complexity entropy-deceiving graphs.
Zenil H, Kiani NA, Tegnér J
Phys Rev E 96 (1-1) 012308 [2017-07-00; online 2017-07-07]
Affiliated researcher
Genomewide analysis of admixture and adaptation in the Africanized honeybee.
Nelson RM, Wallberg A, Simões ZLP, Lawson DJ, Webster MT
Mol. Ecol. 26 (14) 3603-3617 [2017-07-00; online 2017-04-24]
Affiliated researcher
EGR2 mutations define a new clinically aggressive subgroup of chronic lymphocytic leukemia.
Young E, Noerenberg D, Mansouri L, ..., Rosenquist R, Damm F
Leukemia 31 (7) 1547-1554 [2017-07-00; online 2016-11-28]
Affiliated researcher
Detection of 6-demethoxyubiquinone in CoQ
Herebian D, Seibt A, Smits SHJ, ..., Mayatepek E, Distelmaier F
Mol. Genet. Metab. 121 (3) 216-223 [2017-07-00; online 2017-05-20]
Affiliated researcher
Autoimmune polyendocrine syndrome type 1 in an Indian cohort: a longitudinal study.
Zaidi G, Bhatia V, Sahoo SK, ..., Agarwal S, Bhatia E
Endocr Connect 6 (5) 289-296 [2017-07-00; online 2017-04-26]
Affiliated researcher
A longitudinal assessment of miR-122 and GLDH as biomarkers of drug-induced liver injury in the rat.
Thulin P, Hornby RJ, Auli M, ..., Glinghammar B, Schuppe-Koistinen I
Biomarkers 22 (5) 461-469 [2017-07-00; online 2016-12-15]
Affiliated researcher
A human intestinal M-cell-like model for investigating particle, antigen and microorganism translocation.
Beloqui A, Brayden DJ, Artursson P, Préat V, des Rieux A
Nat Protoc 12 (7) 1387-1399 [2017-07-00; online 2017-06-15]
Affiliated researcher
A Low-Frequency Inactivating
Manning A, Highland HM, Gasser J, ..., Gloyn AL, Lindgren CM
Diabetes 66 (7) 2019-2032 [2017-07-00; online 2017-03-24]
Affiliated researcher
Moderate nucleotide diversity in the Atlantic herring is associated with a low mutation rate.
Feng C, Pettersson M, Lamichhaney S, ..., Folkvord A, Andersson L
Elife 6 (-) - [2017-06-30; online 2017-06-30]
Affiliated researcher
Stroma-regulated HMGA2 is an independent prognostic marker in PDAC and AAC.
Strell C, Norberg KJ, Mezheyeuski A, ..., Johansen JS, Östman A
Br. J. Cancer 117 (1) 65-77 [2017-06-27; online 2017-05-18]
Affiliated researcher
Oncolytic alphavirus SFV-VA7 efficiently eradicates subcutaneous and orthotopic human prostate tumours in mice.
Martikainen M, Ruotsalainen J, Tuomela J, ..., Heikkilä J, Hinkkanen A
Br. J. Cancer 117 (1) 51-55 [2017-06-27; online 2017-05-30]
Affiliated researcher
GeneSPIDER - gene regulatory network inference benchmarking with controlled network and data properties.
Tjärnberg A, Morgan DC, Studham M, Nordling TEM, Sonnhammer ELL
Mol Biosyst 13 (7) 1304-1312 [2017-06-27; online 2017-05-10]
Affiliated researcher
Coherent soft X-ray diffraction imaging of coliphage PR772 at the Linac coherent light source.
Reddy HKN, Yoon CH, Aquila A, ..., Williams GJ, Xavier PL
Sci Data 4 (-) 170079 [2017-06-27; online 2017-06-27]
Affiliated researcher
Identification of novel small molecules that inhibit STAT3-dependent transcription and function.
Kolosenko I, Yu Y, Busker S, ..., Page BDG, Grander D
PLoS ONE 12 (6) e0178844 [2017-06-21; online 2017-06-21]
Affiliated researcher
Global Kinetic Mechanism of Microsomal Glutathione Transferase 1 and Insights into Dynamic Enzyme Activation.
Spahiu L, Ålander J, Ottosson-Wadlund A, ..., Armstrong RN, Morgenstern R
Biochemistry 56 (24) 3089-3098 [2017-06-20; online 2017-06-09]
Affiliated researcher
Synthetic approaches to radiochemical probes for imaging of bacterial infections.
Dutta J, Naicker T, Ebenhan T, ..., Arvidsson PI, Govender T
Eur J Med Chem 133 (-) 287-308 [2017-06-16; online 2017-03-29]
Affiliated researcher
Insufficient antibody validation challenges oestrogen receptor beta research.
Andersson S, Sundberg M, Pristovsek N, ..., Williams C, Asplund A
Nat Commun 8 (-) 15840 [2017-06-15; online 2017-06-15]
Affiliated researcher
Identification of the adenovirus type 2 C-168 protein.
Gromova A, Zhao H, Konzer A, ..., Pettersson U, Lind SB
Virus Res. 238 (-) 110-113 [2017-06-15; online 2017-06-16]
Affiliated researcher
Stimulated Emission Depletion Microscopy.
Blom H, Widengren J
Chem. Rev. 117 (11) 7377-7427 [2017-06-14; online 2017-03-06]
Affiliated researcher
Genetic loci associated with heart rate variability and their effects on cardiac disease risk.
Nolte IM, Munoz ML, Tragante V, ..., Snieder H, de Geus EJC
Nat Commun 8 (-) 15805 [2017-06-14; online 2017-06-14]
Affiliated researcher
Correspondence on Lovell et al.: identification of chicken genes previously assumed to be evolutionarily lost.
Bornelöv S, Seroussi E, Yosefi S, ..., Friedman-Einat M, Andersson L
Genome Biol. 18 (1) 112 [2017-06-14; online 2017-06-14]
Affiliated researcher
Loss of Cardioprotective Effects at the
Saleheen D, Zhao W, Young R, ..., Samani NJ, Reilly MP
Circulation 135 (24) 2336-2353 [2017-06-13; online 2017-05-01]
Affiliated researcher
Cohort profile: the Nordic Antireflux Surgery Cohort (NordASCo).
Maret-Ouda J, Wahlin K, Artama M, ..., Euler-Chelpin MV, Lagergren J
BMJ Open 7 (6) e016505 [2017-06-08; online 2017-06-08]
Affiliated researcher
SNX10 gene mutation leading to osteopetrosis with dysfunctional osteoclasts.
Stattin EL, Henning P, Klar J, ..., Wikström J, Lerner UH
Sci Rep 7 (1) 3012 [2017-06-07; online 2017-06-07]
Affiliated researcher
Integrative modeling of gene and genome evolution roots the archaeal tree of life.
Williams TA, Szöllősi GJ, Spang A, ..., Ettema TJG, Embley TM
Proc. Natl. Acad. Sci. U.S.A. 114 (23) E4602-E4611 [2017-06-06; online 2017-05-22]
Affiliated researcher
SAMHD1 protects cancer cells from various nucleoside-based antimetabolites.
Herold N, Rudd SG, Sanjiv K, ..., Henter JI, Schaller T
Cell Cycle 16 (11) 1029-1038 [2017-06-03; online 2017-04-24]
Affiliated researcher
Simultaneous Single-Cell
Krzywkowski T, Ciftci S, Assadian F, Nilsson M, Punga T
J. Virol. 91 (11) - [2017-06-01; online 2017-05-12]
Affiliated researcher
Evidence for large-scale gene-by-smoking interaction effects on pulmonary function.
Aschard H, Tobin MD, Hancock DB, ..., London SJ, Kraft P
Int J Epidemiol 46 (3) 894-904 [2017-06-01; online 2017-01-14]
Affiliated researcher
Role of interferons in SLE.
Bengtsson AA, Rönnblom L
Best Pract Res Clin Rheumatol 31 (3) 415-428 [2017-06-00; online 2017-11-03]
Affiliated researcher
Results of a collaborative study on DNA identification of aged bone samples
Vanek D, Budowle B, Dubska-Votrubova J, ..., Vella J, Zander J
Croat Med J 58 (3) 203-213 [2017-06-00; online 2017-06-00]
Affiliated researcher
Quality Matters: 2016 Annual Conference of the National Infrastructures for Biobanking.
Doucet M, Becker KF, Björkman J, ..., Zatloukal K, Dagher G
Biopreserv Biobank 15 (3) 270-276 [2017-06-00; online 2016-12-19]
Affiliated researcher
Multirate method for co-simulation of electrical-chemical systems in multiscale modeling.
Brocke E, Djurfeldt M, Bhalla US, Kotaleski JH, Hanke M
J Comput Neurosci 42 (3) 245-256 [2017-06-00; online 2017-04-07]
Affiliated researcher
MicroBubble activated acoustic cell sorting.
Faridi MA, Ramachandraiah H, Iranmanesh I, ..., Wiklund M, Russom A
Biomed Microdevices 19 (2) 23 [2017-06-00; online 2017-04-05]
Affiliated researcher
Metastasis detection from whole slide images using local features and random forests.
Valkonen M, Kartasalo K, Liimatainen K, ..., Latonen L, Ruusuvuori P
Cytometry A 91 (6) 555-565 [2017-06-00; online 2017-04-20]
DDLS Fellow Kimmo Kartasalo
Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.
Christophersen IE, Rienstra M, Roselli C, ..., Ellinor PT, AFGen Consortium
Nat. Genet. 49 (6) 946-952 [2017-06-00; online 2017-04-17]
Affiliated researcher
LASSIM-A network inference toolbox for genome-wide mechanistic modeling.
Magnusson R, Mariotti GP, Köpsén M, ..., Tjärnberg A, Gustafsson M
PLoS Comput Biol 13 (6) e1005608 [2017-06-00; online 2017-06-22]
Affiliated researcher
Global survey of the immunomodulatory potential of common drugs.
Vladimer GI, Snijder B, Krall N, ..., Jäger U, Superti-Furga G
Nat. Chem. Biol. 13 (6) 681-690 [2017-06-00; online 2017-04-24]
Affiliated researcher
Genome sequencing and population genomic analyses provide insights into the adaptive landscape of silver birch.
Salojärvi J, Smolander OP, Nieminen K, ..., Helariutta Y, Kangasjärvi J
Nat. Genet. 49 (6) 904-912 [2017-06-00; online 2017-05-08]
Affiliated researcher
Fast and general tests of genetic interaction for genome-wide association studies.
Frånberg M, Strawbridge RJ, Hamsten A, ..., Lagergren J, Sennblad B
PLoS Comput Biol 13 (6) e1005556 [2017-06-00; online 2017-06-06]
Affiliated researcher
Effects of beaver impoundments on dissolved organic matter quality and biodegradability in boreal riverine systems
Catalán N, Herrero Ortega S, Gröntoft H, ..., Bishop K, Bravo AG
Hydrobiologia 793 (1) 135-148 [2017-06-00; online 2016-05-23]
Affiliated researcher
Association analysis of KIT, MITF, and PAX3 variants with white markings in Spanish horses.
Negro S, Imsland F, Valera M, ..., Solé M, Andersson L
Anim. Genet. 48 (3) 349-352 [2017-06-00; online 2017-01-13]
Affiliated researcher
High-affinity recognition of the human C-reactive protein independent of phosphocholine.
Yang J, Gustavsson AL, Haraldsson M, ..., Norberg T, Baltzer L
Org. Biomol. Chem. 15 (21) 4644-4654 [2017-05-31; online 2017-05-18]
Affiliated researcher
Substrate and method dependent inhibition of three ABC-transporters (MDR1, BCRP, and MRP2).
Pedersen JM, Khan EK, Bergström CAS, ..., Hoogstraate J, Artursson P
Eur J Pharm Sci 103 (-) 70-76 [2017-05-30; online 2017-03-02]
Affiliated researcher
Type 2 diabetes and obesity induce similar transcriptional reprogramming in human myocytes.
Väremo L, Henriksen TI, Scheele C, ..., Pedersen BK, Nielsen J
Genome Med 9 (1) 47 [2017-05-25; online 2017-05-25]
Affiliated researcher
Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors.
Llona-Minguez S, Höglund A, Ghassemian A, ..., Scobie M, Helleday T
J. Med. Chem. 60 (10) 4279-4292 [2017-05-25; online 2017-05-16]
Affiliated researcher
RNA-dependent chromatin association of transcription elongation factors and Pol II CTD kinases.
Battaglia S, Lidschreiber M, Baejen C, ..., Vos SM, Cramer P
Elife 6 (-) - [2017-05-24; online 2017-05-24]
Affiliated researcher
Selective Synthesis of Spirooxindoles by an Intramolecular Heck-Mizoroki Reaction.
Roy T, Brandt P, Wetzel A, ..., Sävmarker J, Larhed M
Org. Lett. 19 (10) 2738-2741 [2017-05-19; online 2017-05-04]
Affiliated researcher
AT
Bernhem K, Krishnan K, Bondar A, ..., Aperia A, Scott L
BMC Cardiovasc Disord 17 (1) 126 [2017-05-17; online 2017-05-17]
Affiliated researcher
ProQ3D: improved model quality assessments using deep learning.
Uziela K, Menéndez Hurtado D, Shu N, Wallner B, Elofsson A
Bioinformatics 33 (10) 1578-1580 [2017-05-15; online 2017-01-06]
Affiliated researcher
GWAR: robust analysis and meta-analysis of genome-wide association studies.
Dimou NL, Tsirigos KD, Elofsson A, Bagos PG
Bioinformatics 33 (10) 1521-1527 [2017-05-15; online 2017-01-22]
Affiliated researcher
Expression proteomics study to determine metallodrug targets and optimal drug combinations.
Lee RFS, Chernobrovkin A, Rutishauser D, ..., Zubarev RA, Dyson PJ
Sci Rep 7 (1) 1590 [2017-05-08; online 2017-05-08]
Affiliated researcher
EndoC-βH1 cells display increased sensitivity to sodium palmitate when cultured in DMEM/F12 medium.
Krizhanovskii C, Kristinsson H, Elksnis A, ..., Scharfmann R, Welsh N
Islets 9 (3) e1296995 [2017-05-04; online 2017-02-28]
Affiliated researcher
Experimental strategies for imaging bioparticles with femtosecond hard X-ray pulses.
Daurer BJ, Okamoto K, Bielecki J, ..., Hajdu J, Larsson DSD
IUCrJ 4 (Pt 3) 251-262 [2017-05-01; online 2017-04-07]
Affiliated researcher
[ 11C]5-hydroxy-tryptophan PET for Assessment of Islet Mass During Progression of Type 2 Diabetes.
Carlbom L, Espes D, Lubberink M, ..., Korsgren O, Eriksson O
Diabetes 66 (5) 1286-1292 [2017-05-00; online 2017-02-28]
Olof Eriksson SciLifeLab Fellow
Transcriptomics and methylomics of CD4-positive T cells in arsenic-exposed women.
Engström K, Wojdacz TK, Marabita F, ..., Vahter M, Broberg K
Arch. Toxicol. 91 (5) 2067-2078 [2017-05-00; online 2016-11-12]
Affiliated researcher
Time to onset of bisphosphonate-related osteonecrosis of the jaws: a multicentre retrospective cohort study.
Fung P, Bedogni G, Bedogni A, ..., GENVABO Consortium , Fedele S
Oral Dis 23 (4) 477-483 [2017-05-00; online 2017-03-06]
Affiliated researcher
Safe and Effective Sarcoma Therapy through Bispecific Targeting of EGFR and uPAR.
Borgatti A, Koopmeiners JS, Sarver AL, ..., Modiano JF, Vallera DA
Mol. Cancer Ther. 16 (5) 956-965 [2017-05-00; online 2017-02-13]
Affiliated researcher
Inflammatory markers in late pregnancy in association with postpartum depression-A nested case-control study.
Bränn E, Papadopoulos F, Fransson E, ..., Sundström-Poromaa I, Skalkidou A
Psychoneuroendocrinology 79 (-) 146-159 [2017-05-00; online 2017-02-28]
Affiliated researcher
Evolutionary forces affecting synonymous variations in plant genomes.
Clément Y, Sarah G, Holtz Y, ..., David J, Glémin S
PLoS Genet 13 (5) e1006799 [2017-05-00; online 2017-05-22]
Affiliated researcher
Enhanced sensitivity to glucocorticoids in cytarabine-resistant AML.
Malani D, Murumägi A, Yadav B, ..., Aittokallio T, Kallioniemi O
Leukemia 31 (5) 1187-1195 [2017-05-00; online 2016-11-11]
Affiliated researcher
1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.
Gorski M, van der Most PJ, Teumer A, ..., Böger CA, Fuchsberger C
Sci Rep 7 (-) 45040 [2017-04-28; online 2017-04-28]
Affiliated researcher
Persistent Effects of Developmental Exposure to 17α-Ethinylestradiol on the Zebrafish (
Porseryd T, Volkova K, Reyhanian Caspillo N, ..., Dinnetz P, Porsh Hällström I
Front Behav Neurosci 11 (-) 69 [2017-04-20; online 2017-04-20]
Affiliated researcher
Oriented clonal cell dynamics enables accurate growth and shaping of vertebrate cartilage.
Kaucka M, Zikmund T, Tesarova M, ..., Fried K, Adameyko I
Elife 6 (-) - [2017-04-17; online 2017-04-17]
Affiliated researcher
Improved orthology inference with Hieranoid 2.
Kaduk M, Sonnhammer E
Bioinformatics 33 (8) 1154-1159 [2017-04-15; online 2017-01-18]
Affiliated researcher
Adaptation to infectious disease exposure in indigenous Southern African populations.
Owers KA, Sjödin P, Schlebusch CM, ..., Soodyall H, Jakobsson M
Proc. Biol. Sci. 284 (1852) - [2017-04-12; online 2017-04-07]
Affiliated researcher
Direct evidence for a polygenic etiology in familial multiple myeloma.
Halvarsson BM, Wihlborg AK, Ali M, ..., Hansson M, Nilsson B
Blood Adv 1 (10) 619-623 [2017-04-11; online 2017-04-07]
Abhishek Niroula DDLS Fellow
Genome-wide Analysis of RNA Polymerase II Termination at Protein-Coding Genes.
Baejen C, Andreani J, Torkler P, ..., Söding J, Cramer P
Mol. Cell 66 (1) 38-49.e6 [2017-04-06; online 2017-03-16]
Affiliated researcher
Quantum dots modulate intracellular Ca
Yin H, Fontana JM, Solandt J, ..., Brismar H, Fu Y
Int J Nanomedicine 12 (-) 2781-2792 [2017-04-05; online 2017-04-05]
Affiliated researcher
dUTPase inhibition augments replication defects of 5-Fluorouracil.
Hagenkort A, Paulin CBJ, Desroses M, ..., Scobie M, Helleday T
Oncotarget 8 (14) 23713-23726 [2017-04-04; online 2017-04-21]
Affiliated researcher
Optimizing Analytical Depth and Cost Efficiency of IEF-LC/MS Proteomics.
Kifer I, Branca RM, Ben-Dor A, ..., Lehtio J, Yakhini Z
IEEE/ACM Trans Comput Biol Bioinform 14 (2) 272-281 [2017-04-04; online 2017-04-04]
Affiliated researcher
Flow Cytometric Measurement of Blood Cells with BCR-ABL1 Fusion Protein in Chronic Myeloid Leukemia.
Löf L, Arngården L, Olsson-Strömberg U, ..., Landegren U, Kamali-Moghaddam M
Sci Rep 7 (1) 623 [2017-04-04; online 2017-04-04]
Affiliated researcher
Sulfonimidamides in Medicinal and Agricultural Chemistry.
Chinthakindi PK, Naicker T, Thota N, ..., Kruger HG, Arvidsson PI
Angew. Chem. Int. Ed. Engl. 56 (15) 4100-4109 [2017-04-03; online 2017-02-23]
Affiliated researcher
Somatic Ephrin Receptor Mutations Are Associated with Metastasis in Primary Colorectal Cancer.
Mathot L, Kundu S, Ljungström V, ..., Nilsson M, Sjöblom T
Cancer Res. 77 (7) 1730-1740 [2017-04-01; online 2017-01-20]
Affiliated researcher
Menopausal hormone therapy and the risk of esophageal and gastric cancer.
Brusselaers N, Maret-Ouda J, Konings P, El-Serag HB, Lagergren J
Int. J. Cancer 140 (7) 1693-1699 [2017-04-01; online 2017-01-06]
Affiliated researcher
Discrimination of pancreatic cancer and pancreatitis by LC-MS metabolomics.
Lindahl A, Heuchel R, Forshed J, ..., Löhr M, Nordström A
Metabolomics 13 (5) 61 [2017-04-01; online 2017-04-01]
Affiliated researcher
The evolution of Sex-linked barring alleles in chickens involves both regulatory and coding changes in CDKN2A.
Schwochow Thalmann D, Ring H, Sundström E, ..., Tixier-Boichard M, Andersson L
PLoS Genet 13 (4) e1006665 [2017-04-00; online 2017-04-07]
Affiliated researcher
Sensitive magnetic biodetection using magnetic multi-core nanoparticles and RCA coils
Ahrentorp F, Blomgren J, Jonasson C, ..., Strømme M, Johansson C
Journal of Magnetism and Magnetic Materials 427 (-) 14-18 [2017-04-00; online 2017-04-00]
Affiliated researcher
Prediction and Prevention of Parasitic Diseases Using a Landscape Genomics Framework.
Schwabl P, Llewellyn MS, Landguth EL, ..., Ocaña S, Grijalva MJ
Trends Parasitol. 33 (4) 264-275 [2017-04-00; online 2016-11-16]
Affiliated researcher
Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease.
Folkersen L, Fauman E, Sabater-Lleal M, ..., Hamsten A, Mälarstig A
PLoS Genet 13 (4) e1006706 [2017-04-00; online 2017-04-03]
Affiliated researcher
Human behavioral complexity peaks at age 25.
Gauvrit N, Zenil H, Soler-Toscano F, Delahaye JP, Brugger P
PLoS Comput Biol 13 (4) e1005408 [2017-04-00; online 2017-04-13]
Affiliated researcher
Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.
Graff M, Scott RA, Justice AE, ..., Loos RJF, Kilpeläinen TO
PLoS Genet 13 (4) e1006528 [2017-04-00; online 2017-04-27]
Affiliated researcher
Frequent low-level mutations of protein kinase D2 in angiolipoma.
Hofvander J, Arbajian E, Stenkula KG, ..., Hornick JL, Mertens F
J. Pathol. 241 (5) 578-582 [2017-04-00; online 2017-02-27]
Affiliated researcher
FZD
Hot B, Valnohova J, Arthofer E, ..., Mulder J, Schulte G
Cell. Signal. 32 (-) 93-103 [2017-04-00; online 2017-01-24]
Affiliated researcher
Expanding the product portfolio of fungal type I fatty acid synthases.
Zhu Z, Zhou YJ, Krivoruchko A, ..., Zhao ZK, Nielsen J
Nat. Chem. Biol. 13 (4) 360-362 [2017-04-00; online 2017-02-20]
Affiliated researcher
Epigenome-wide DNA methylation study of IgE concentration in relation to self-reported allergies.
Ek WE, Ahsan M, Rask-Andersen M, ..., Gyllensten U, Johansson Å
Epigenomics 9 (4) 407-418 [2017-04-00; online 2017-03-21]
Affiliated researcher
Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.
Nicoletti P, Aithal GP, Bjornsson ES, ..., Daly AK, International Drug-Induced Liver Injury Consortium, Drug-Induced Liver Injury Network Investigators, and International Serious Adverse Events Consortium
Gastroenterology 152 (5) 1078-1089 [2017-04-00; online 2016-12-30]
Affiliated researcher
Analysis of FOXP3
Schmidt A, Rieger CC, Venigalla RK, ..., Krammer PH, Kuhn A
Immunol. Res. 65 (2) 551-563 [2017-04-00; online 2017-02-23]
Affiliated researcher
Electroformation of Giant Unilamellar Vesicles on Stainless Steel Electrodes.
Pereno V, Carugo D, Bau L, ..., Eggeling C, Stride E
ACS Omega 2 (3) 994-1002 [2017-03-31; online 2017-03-16]
Erdinc Sezgin SciLifeLab Fellow
Improvement of identification methods for honeybee specific Lactic Acid Bacteria; future approaches.
Lamei S, Hu YO, Olofsson TC, ..., Forsgren E, Vásquez A
PLoS ONE 12 (3) e0174614 [2017-03-27; online 2017-03-27]
Affiliated researcher
Modeling and Targeting MYC Genes in Childhood Brain Tumors.
Hutter S, Bolin S, Weishaupt H, Swartling FJ
Genes (Basel) 8 (4) - [2017-03-23; online 2017-03-23]
Affiliated researcher
Helicobacter pylori eradication in the Swedish population.
Doorakkers E, Lagergren J, Gajulapuri VK, ..., Engstrand L, Brusselaers N
Scand. J. Gastroenterol. 52 (6-7) 678-685 [2017-03-21; online 2017-03-21]
Affiliated researcher
Electrochemical Genetic Profiling of Single Cancer Cells.
Acero Sánchez JL, Joda H, Henry OY, ..., Latta D, O'Sullivan CK
Anal. Chem. 89 (6) 3378-3385 [2017-03-21; online 2017-02-28]
Affiliated researcher
Reversion of antibiotic resistance in Mycobacterium tuberculosis by spiroisoxazoline SMARt-420.
Blondiaux N, Moune M, Desroses M, ..., Willand N, Baulard AR
Science 355 (6330) 1206-1211 [2017-03-17; online 2017-03-16]
Affiliated researcher
PATZ1 down-regulates FADS1 by binding to rs174557 and is opposed by SP1/SREBP1c.
Pan G, Ameur A, Enroth S, ..., Gyllensten U, Wadelius C
Nucleic Acids Res. 45 (5) 2408-2422 [2017-03-17; online 2016-12-10]
Affiliated researcher
Total biosynthesis of the cyclic AMP booster forskolin from
Pateraki I, Andersen-Ranberg J, Jensen NB, ..., Møller BL, Hamberger B
Elife 6 (-) - [2017-03-14; online 2017-03-14]
Affiliated researcher
Microbial community assembly and evolution in subseafloor sediment.
Starnawski P, Bataillon T, Ettema TJ, ..., Schramm A, Kjeldsen KU
Proc. Natl. Acad. Sci. U.S.A. 114 (11) 2940-2945 [2017-03-14; online 2017-02-27]
Affiliated researcher
Immunogenicity is preferentially induced in sparse dendritic cell cultures.
Nasi A, Bollampalli VP, Sun M, ..., Rothfuchs AG, Réthi B
Sci Rep 7 (-) 43989 [2017-03-09; online 2017-03-09]
Affiliated researcher
Identification of Triazolothiadiazoles as Potent Inhibitors of the dCTP Pyrophosphatase 1.
Llona-Minguez S, Höglund A, Wiita E, ..., Scobie M, Helleday T
J. Med. Chem. 60 (5) 2148-2154 [2017-03-09; online 2017-02-15]
Affiliated researcher
Discovery of circulating proteins associated to knee radiographic osteoarthritis.
Lourido L, Ayoglu B, Fernández-Tajes J, ..., Nilsson P, Blanco FJ
Sci Rep 7 (1) 137 [2017-03-09; online 2017-03-09]
Affiliated researcher
Whole-Proteome Peptide Microarrays for Profiling Autoantibody Repertoires within Multiple Sclerosis and Narcolepsy.
Zandian A, Forsström B, Häggmark-Månberg A, ..., Nilsson P, Ayoglu B
J. Proteome Res. 16 (3) 1300-1314 [2017-03-03; online 2017-02-09]
Affiliated researcher
A hybrid method for the imputation of genomic data in livestock populations.
Antolín R, Nettelblad C, Gorjanc G, Money D, Hickey JM
Genet. Sel. Evol. 49 (1) 30 [2017-03-03; online 2017-03-03]
Affiliated researcher
Gentle, fast and effective crystal soaking by acoustic dispensing.
Collins PM, Ng JT, Talon R, ..., Pearce NM, von Delft F
Acta Crystallogr D Struct Biol 73 (Pt 3) 246-255 [2017-03-01; online 2017-03-06]
DDLS Fellow Nicholas Pearce
Estrogen Receptor β as a Therapeutic Target in Breast Cancer Stem Cells.
Ma R, Karthik GM, Lövrot J, ..., Fredriksson I, Hartman J
J. Natl. Cancer Inst. 109 (3) 1-14 [2017-03-01; online 2017-04-05]
Affiliated researcher
Tracing Cellular Origin of Human Exosomes Using Multiplex Proximity Extension Assays.
Larssen P, Wik L, Czarnewski P, ..., Gabrielsson S, Kamali-Moghaddam M
Mol. Cell Proteomics 16 (3) 502-511 [2017-03-00; online 2017-01-22]
Affiliated researcher
The use of a Swedish telephone medical advice service by the elderly - a population-based study.
Dahlgren K, Holzmann MJ, Carlsson AC, ..., Hasselström J, Ruge T
Scand J Prim Health Care 35 (1) 98-104 [2017-03-00; online 2017-03-03]
Affiliated researcher
Phylogenetic analysis of
Barbosa RN, Leong SL, Vinnere-Pettersson O, ..., Oliveira NT, Houbraken J
Stud. Mycol. 86 (-) 29-51 [2017-03-00; online 2017-04-12]
Affiliated researcher
Overexpression of heparanase attenuated TGF-β-stimulated signaling in tumor cells.
Batool T, Fang J, Barash U, ..., Vlodavsky I, Li JP
FEBS Open Bio 7 (3) 405-413 [2017-03-00; online 2017-02-11]
Affiliated researcher
Human ROBO1 regulates white matter structure in corpus callosum.
Darki F, Massinen S, Salmela E, ..., Klingberg T, Kere J
Brain Struct Funct 222 (2) 707-716 [2017-03-00; online 2016-05-30]
Affiliated researcher
High GC content causes orphan proteins to be intrinsically disordered.
Basile W, Sachenkova O, Light S, Elofsson A
PLoS Comput Biol 13 (3) e1005375 [2017-03-00; online 2017-03-29]
Affiliated researcher
Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.
Warren HR, Evangelou E, Cabrera CP, ..., International Genomics of Blood Pressure (iGEN-BP) Consortium , UK Biobank CardioMetabolic Consortium BP working group
Nat. Genet. 49 (3) 403-415 [2017-03-00; online 2017-01-30]
Affiliated researcher
Development of [
Stepanov V, Svedberg M, Jia Z, ..., Nordberg A, Halldin C
Nucl. Med. Biol. 46 (-) 50-53 [2017-03-00; online 2016-12-09]
Affiliated researcher
Cotranslational folding of spectrin domains via partially structured states.
Nilsson OB, Nickson AA, Hollins JJ, ..., von Heijne G, Clarke J
Nat. Struct. Mol. Biol. 24 (3) 221-225 [2017-03-00; online 2017-01-23]
Affiliated researcher
Biomimetic spinning of artificial spider silk from a chimeric minispidroin.
Andersson M, Jia Q, Abella A, ..., Johansson J, Rising A
Nat. Chem. Biol. 13 (3) 262-264 [2017-03-00; online 2017-01-09]
Affiliated researcher
Functional genomics analysis of vitamin D effects on CD4+ T cells in vivo in experimental autoimmune encephalomyelitis ‬.
Zeitelhofer M, Adzemovic MZ, Gomez-Cabrero D, ..., Guerreiro-Cacais AO, Jagodic M
Proc. Natl. Acad. Sci. U.S.A. 114 (9) E1678-E1687 [2017-02-28; online 2017-02-14]
Affiliated researcher
Intracellular drug bioavailability: a new predictor of system dependent drug disposition.
Mateus A, Treyer A, Wegler C, ..., Matsson P, Artursson P
Sci Rep 7 (-) 43047 [2017-02-22; online 2017-02-22]
Affiliated researcher
Comparison of whole genome amplification techniques for human single cell exome sequencing.
Borgström E, Paterlini M, Mold JE, Frisen J, Lundeberg J
PLoS ONE 12 (2) e0171566 [2017-02-16; online 2017-02-16]
Affiliated researcher
Nitration of MOG diminishes its encephalitogenicity depending on MHC haplotype.
Warnecke A, Musunuri S, N'diaye M, ..., Bergquist J, Harris RA
J. Neuroimmunol. 303 (-) 1-12 [2017-02-15; online 2016-11-26]
Affiliated researcher
Crystal Structure of the Emerging Cancer Target MTHFD2 in Complex with a Substrate-Based Inhibitor.
Gustafsson R, Jemth AS, Gustafsson NM, ..., Helleday T, Stenmark P
Cancer Res. 77 (4) 937-948 [2017-02-15; online 2016-11-29]
Affiliated researcher
The Baltic Sea Virome: Diversity and Transcriptional Activity of DNA and RNA Viruses.
Zeigler Allen L, McCrow JP, Ininbergs K, ..., Bergman B, Venter JC
mSystems 2 (1) - [2017-02-14; online 2017-02-14]
Affiliated researcher
A novel RNA sequencing data analysis method for cell line authentication.
Fasterius E, Raso C, Kennedy S, ..., Uhlén M, Al-Khalili Szigyarto C
PLoS ONE 12 (2) e0171435 [2017-02-13; online 2017-02-13]
Affiliated researcher
Genetic and Functional Study of L-Type Amino Acid Transporter 1 in Schizophrenia.
Comasco E, Vumma R, Toffoletto S, ..., Jönsson EG, Venizelos N
Neuropsychobiology 74 (2) 96-103 [2017-02-11; online 2017-02-11]
Erika Comasco SciLifeLab Fellow
Nanometer resolution imaging and tracking of fluorescent molecules with minimal photon fluxes.
Balzarotti F, Eilers Y, Gwosch KC, ..., Elf J, Hell SW
Science 355 (6325) 606-612 [2017-02-10; online 2016-12-22]
Affiliated researcher
Rare and low-frequency coding variants alter human adult height.
Marouli E, Graff M, Medina-Gomez C, ..., Deloukas P, Lettre G
Nature 542 (7640) 186-190 [2017-02-09; online 2017-02-01]
Affiliated researcher
Molecular composition of organic matter controls methylmercury formation in boreal lakes.
Bravo AG, Bouchet S, Tolu J, ..., Mateos-Rivera A, Bertilsson S
Nat Commun 8 (-) 14255 [2017-02-09; online 2017-02-09]
Affiliated researcher
Posttranscriptional Regulation in Adenovirus Infected Cells.
Zhao H, Konzer A, Mi J, ..., Pettersson U, Lind SB
J. Proteome Res. 16 (2) 872-888 [2017-02-03; online 2016-12-13]
Affiliated researcher
A Synthesis of "Dual Warhead" β-Aryl Ethenesulfonyl Fluorides and One-Pot Reaction to β-Sultams.
Chinthakindi PK, Govender KB, Kumar AS, ..., Naicker T, Arvidsson PI
Org. Lett. 19 (3) 480-483 [2017-02-03; online 2017-01-11]
Affiliated researcher
The Human Adrenal Gland Proteome Defined by Transcriptomics and Antibody-Based Profiling.
Bergman J, Botling J, Fagerberg L, ..., Uhlén M, Pontén F
Endocrinology 158 (2) 239-251 [2017-02-01; online 2016-12-03]
Affiliated researcher
Massive parallel sequencing questions the pathogenic role of missense variants in dilated cardiomyopathy.
Dalin MG, Engström PG, Ivarsson EG, ..., Andersson B, Bergo MO
Int. J. Cardiol. 228 (-) 742-748 [2017-02-01; online 2016-11-09]
Affiliated researcher
Targeting SAMHD1 with the Vpx protein to improve cytarabine therapy for hematological malignancies.
Herold N, Rudd SG, Ljungblad L, ..., Helleday T, Schaller T
Nat. Med. 23 (2) 256-263 [2017-02-00; online 2017-01-09]
Affiliated researcher
Self-correcting mismatches during high-fidelity DNA replication.
Fernandez-Leiro R, Conrad J, Yang JC, ..., Scheres SH, Lamers MH
Nat. Struct. Mol. Biol. 24 (2) 140-143 [2017-02-00; online 2017-01-09]
Affiliated researcher
Robust, universal biomarker assay to detect senescent cells in biological specimens.
Evangelou K, Lougiakis N, Rizou SV, ..., Bartek J, Gorgoulis VG
Aging Cell 16 (1) 192-197 [2017-02-00; online 2016-11-17]
Affiliated researcher
PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study
Schmidt AF, Swerdlow DI, Holmes MV, ..., Hingorani AD, Sattar N
The Lancet Diabetes & Endocrinology 5 (2) 97-105 [2017-02-00; online 2017-02-00]
Affiliated researcher
Opioid precursor protein isoform is targeted to the cell nuclei in the human brain.
Kononenko O, Bazov I, Watanabe H, ..., Yakovleva T, Bakalkin G
Biochim Biophys Acta Gen Subj 1861 (2) 246-255 [2017-02-00; online 2016-11-10]
Affiliated researcher
Mosaicism in health and disease - clones picking up speed.
Forsberg LA, Gisselsson D, Dumanski JP
Nat. Rev. Genet. 18 (2) 128-142 [2017-02-00; online 2016-12-12]
Affiliated researcher
Molecular interrogation of hypothalamic organization reveals distinct dopamine neuronal subtypes.
Romanov RA, Zeisel A, Bakker J, ..., Horvath TL, Harkany T
Nat. Neurosci. 20 (2) 176-188 [2017-02-00; online 2016-12-19]
Affiliated researcher
Mercury Human Exposure in Populations Living Around Lake Tana (Ethiopia).
Habiba G, Abebe G, Bravo AG, ..., Staffan Ǻ, Bishop K
Biol Trace Elem Res 175 (2) 237-243 [2017-02-00; online 2016-06-09]
Affiliated researcher
Antigen receptor stereotypy in chronic lymphocytic leukemia.
Stamatopoulos K, Agathangelidis A, Rosenquist R, Ghia P
Leukemia 31 (2) 282-291 [2017-02-00; online 2016-11-04]
Affiliated researcher
c-Jun-N-terminal phosphorylation regulates DNMT1 expression and genome wide methylation in gliomas.
Heiland DH, Ferrarese R, Claus R, ..., Nelander S, Carro MS
Oncotarget 8 (4) 6940-6954 [2017-01-24; online 2016-12-31]
Affiliated researcher
Glioblastoma Cell Malignancy and Drug Sensitivity Are Affected by the Cell of Origin.
Jiang Y, Marinescu VD, Xie Y, ..., Nelander S, Uhrbom L
Cell Reports 18 (4) 977-990 [2017-01-24; online 2017-01-26]
Affiliated researcher
Asgard archaea illuminate the origin of eukaryotic cellular complexity.
Zaremba-Niedzwiedzka K, Caceres EF, Saw JH, ..., Spang A, Ettema TJ
Nature 541 (7637) 353-358 [2017-01-19; online 2017-01-11]
Affiliated researcher
Novel genetic loci associated with hippocampal volume.
Hibar DP, Adams HHH, Jahanshad N, ..., Thompson PM, Ikram MA
Nat Commun 8 (-) 13624 [2017-01-18; online 2017-01-18]
Affiliated researcher
Lithium Accumulates in Neurogenic Brain Regions as Revealed by High Resolution Ion Imaging.
Zanni G, Michno W, Di Martino E, ..., Blomgren K, Hanrieder J
Sci Rep 7 (-) 40726 [2017-01-18; online 2017-01-18]
SciLifeLab Fellow Wojciech Michno
Targeted DNA sequencing and in situ mutation analysis using mobile phone microscopy.
Kühnemund M, Wei Q, Darai E, ..., Ozcan A, Nilsson M
Nat Commun 8 (-) 13913 [2017-01-17; online 2017-01-17]
Affiliated researcher
Ameloblastoma RNA profiling uncovers a distinct non-coding RNA signature.
Davanian H, Balasiddaiah A, Heymann R, ..., Kruger Weiner C, Chen M
Oncotarget 8 (3) 4530-4542 [2017-01-17; online 2016-12-15]
Affiliated researcher
Architecture of the yeast small subunit processome.
Chaker-Margot M, Barandun J, Hunziker M, Klinge S
Science 355 (6321) - [2017-01-13; online 2016-12-15]
Jonas Barandun SciLifeLab Fellow
Rituximab capping triggers intracellular reorganization of B cells
Koller T, Blok S, Santos AM, ..., Sezgin E, Eggeling C
Matters - (-) - [2017-01-12; online 2017-01-12]
Erdinc Sezgin SciLifeLab Fellow
New insights into the GINS complex explain the controversy between existing structural models.
Carroni M, De March M, Medagli B, ..., Patwardhan A, Onesti S
Sci Rep 7 (-) 40188 [2017-01-10; online 2017-01-10]
Affiliated researcher
Identification of a Novel Autoimmune Peptide Epitope of Prostein in Prostate Cancer.
Pin E, Henjes F, Hong MG, ..., Nilsson P, Schwenk JM
J. Proteome Res. 16 (1) 204-216 [2017-01-06; online 2016-10-24]
Affiliated researcher
Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity.
Wahl S, Drong A, Lehne B, ..., Grallert H, Chambers JC
Nature 541 (7635) 81-86 [2017-01-05; online 2016-12-21]
Affiliated researcher
HieranoiDB: a database of orthologs inferred by Hieranoid.
Kaduk M, Riegler C, Lemp O, Sonnhammer EL
Nucleic Acids Res. 45 (D1) D687-D690 [2017-01-04; online 2016-10-13]
Affiliated researcher
DisProt 7.0: a major update of the database of disordered proteins.
Piovesan D, Tabaro F, Mičetić I, ..., Tompa P, Tosatto SC
Nucleic Acids Res. 45 (D1) D219-D227 [2017-01-04; online 2016-11-28]
Affiliated researcher
Sex differences in depression during pregnancy and the postpartum period.
Sundström Poromaa I, Comasco E, Georgakis MK, Skalkidou A
J Neurosci Res 95 (1-2) 719-730 [2017-01-02; online 2016-11-22]
Erika Comasco SciLifeLab Fellow
Comprehensive RNA sequencing of healthy human endometrium at two time points of the menstrual cycle.
Sigurgeirsson B, Åmark H, Jemt A, ..., Lundeberg J, Gidlöf S
Biol. Reprod. 96 (1) 24-33 [2017-01-01; online 2017-04-11]
Affiliated researcher
CADEE: Computer-Aided Directed Evolution of Enzymes.
Amrein BA, Steffen-Munsberg F, Szeler I, ..., Kulkarni Y, Kamerlin SCL
IUCrJ 4 (Pt 1) 50-64 [2017-01-01; online 2017-01-01]
Affiliated researcher
Why mitochondria need a genome revisited.
Björkholm P, Ernst AM, Hagström E, Andersson SG
FEBS Lett. 591 (1) 65-75 [2017-01-00; online 2016-12-20]
Affiliated researcher
Whole gene duplication of SCN2A and SCN3A is associated with neonatal seizures and a normal intellectual development.
Thuresson AC, Van Buggenhout G, Sheth F, ..., Clayton Smith J, Soussi Zander C
Clin. Genet. 91 (1) 106-110 [2017-01-00; online 2016-06-02]
Affiliated researcher
Targeting TGF-β Signaling in Cancer.
Colak S, Ten Dijke P
Trends Cancer 3 (1) 56-71 [2017-01-00; online 2017-01-03]
Affiliated researcher
Mutational analysis of protein folding inside the ribosome exit tunnel.
Farías-Rico JA, Goetz SK, Marino J, von Heijne G
FEBS Lett. 591 (1) 155-163 [2017-01-00; online 2016-12-20]
Affiliated researcher
Multispecies genetic structure and hybridization in the Betula genus across Eurasia.
Tsuda Y, Semerikov V, Sebastiani F, Vendramin GG, Lascoux M
Mol. Ecol. 26 (2) 589-605 [2017-01-00; online 2016-12-24]
Affiliated researcher
Lake bacterioplankton dynamics over diurnal timescales
Grubisic LM, Bertilsson S, Eiler A, ..., Riemann L, Beier S
Freshw Biol 62 (1) 191-204 [2017-01-00; online 2016-12-16]
Affiliated researcher
Kynurenic acid and psychotic symptoms and personality traits in twins with psychiatric morbidity.
Kegel ME, Johansson V, Wetterberg L, ..., Hultman CM, Erhardt S
Psychiatry Res 247 (-) 105-112 [2017-01-00; online 2016-11-16]
Affiliated researcher
Investigating kinship of Neolithic post-LBK human remains from Krusza Zamkowa, Poland using ancient DNA.
Juras A, Chyleński M, Krenz-Niedbała M, ..., Jakobsson M, Dabert M
Forensic Sci Int Genet 26 (-) 30-39 [2017-01-00; online 2016-10-14]
Affiliated researcher
Human immune system variation.
Brodin P, Davis MM
Nat. Rev. Immunol. 17 (1) 21-29 [2017-01-00; online 2016-12-05]
Affiliated researcher
Flow-cytometric screening of aggregation-inhibitors using a fluorescence-assisted intracellular method.
Lindberg H, Sandersjöö L, Meister SW, ..., Löfblom J, Ståhl S
Biotechnol J 12 (1) - [2017-01-00; online 2016-12-01]
Affiliated researcher
Expression of possible targets for new proteasome inhibitors in diffuse large B-cell lymphoma.
Delforoush M, Berglund M, Edqvist PH, ..., Gullbo J, Enblad G
Eur. J. Haematol. 98 (1) 52-56 [2017-01-00; online 2016-07-12]
Affiliated researcher
Evolutionary engineering reveals divergent paths when yeast is adapted to different acidic environments.
Fletcher E, Feizi A, Bisschops MMM, ..., Siewers V, Nielsen J
Metab. Eng. 39 (-) 19-28 [2017-01-00; online 2016-11-02]
Affiliated researcher
Environmental Risk Factors for Diabetes Mellitus in Cats.
Öhlund M, Egenvall A, Fall T, ..., Röcklinsberg H, Holst BS
J. Vet. Intern. Med. 31 (1) 29-35 [2017-01-00; online 2016-12-01]
Affiliated researcher
Elevated levels of circulating CDH5 and FABP1 in association with human drug-induced liver injury.
Mikus M, Drobin K, Gry M, ..., Nilsson P, Schuppe-Koistinen I
Liver Int. 37 (1) 132-140 [2017-01-00; online 2016-06-22]
Affiliated researcher
Different functions of AKT1 and AKT2 in molecular pathways, cell migration and metabolism in colon cancer cells.
Häggblad Sahlberg S, Mortensen AC, Haglöf J, ..., Stenerlöw B, Nestor M
Int. J. Oncol. 50 (1) 5-14 [2017-01-00; online 2016-11-18]
Affiliated researcher
Deep Fish.
Ishaq O, Sadanandan SK, Wählby C
SLAS Discov 22 (1) 102-107 [2017-01-00; online 2016-09-26]
Affiliated researcher
Cost and clinical outcome of islet transplantation in Norway 2010-2015.
Schive SW, Foss A, Sahraoui A, ..., Mishra V, Scholz H
Clin Transplant 31 (1) - [2017-01-00; online 2016-12-09]
Affiliated researcher
Both maternal and offspring Elovl2 genotypes determine systemic DHA levels in perinatal mice.
Pauter AM, Trattner S, Gonzalez-Bengtsson A, ..., Dethlefsen O, Jacobsson A
J. Lipid Res. 58 (1) 111-123 [2017-01-00; online 2016-11-18]
Affiliated researcher
A multi-step peptidolytic cascade for amino acid recovery in chloroplasts.
Teixeira PF, Kmiec B, Branca RM, ..., Lehtiö J, Glaser E
Nat. Chem. Biol. 13 (1) 15-17 [2017-01-00; online 2016-10-31]
Affiliated researcher
Tumoral ANXA1 Is a Predictive Marker for Sunitinib Treatment of Renal Cancer Patients
Niinivirta M, Enblad G, Edqvist PH, ..., Dragomir A, Ullenhag GJ
J. Cancer 8 (19) 3975-3983 [2017-00-00; online 2017-00-00]
Affiliated researcher
Slipdisc: a versatile sample preparation platform for point of care diagnostics
Banerjee I, Salih T, Ramachandraiah H, ..., Karlsson M, Russom A
RSC Adv. 7 (56) 35048-35054 [2017-00-00; online 2017-00-00]
Affiliated researcher
Lignin depolymerization to monophenolic compounds in a flow-through system
Kumaniaev I, Subbotina E, Sävmarker J, ..., Galkin MV, Samec JSM
Green Chem. 19 (24) 5767-5771 [2017-00-00; online 2017-00-00]
Affiliated researcher
Evolution of Resistance to Insecticide in Disease Vectors
Labbé P, David JP, Alout H, ..., Pasteur N, Weill M
- - (-) 313-339 [2017-00-00; online 2017-00-00]
Pascal Milesi SciLifeLab Fellow

Publications 9.5.1