Publications 2023

1277 publications

Small vessel disease in primary familial brain calcification with novel truncating PDGFB variants.
Yektay Farahmand M, Wasselius J, Englund E, ..., Puschmann A, Ilinca A
Neurol Neurochir Pol 58 (1) 94-105 [2023-12-29; online 2023-12-29]
Mitotic MTH1 inhibitor TH1579 induces PD-L1 expression and inflammatory response through the cGAS-STING pathway
Helleday T, Shen J, Mancina E, ..., Berglund U, Sanjiv K
- - (-) - [2023-12-28; online 2023-12-28]
A multiscale model of striatum microcircuit dynamics
Tesler F, Kozlov A, Grillner S, Destexhe A
- - (-) - [2023-12-28; online 2023-12-28]
Mapping of the gene network that regulates glycan clock of ageing.
Frkatović-Hodžić A, Mijakovac A, Miškec K, ..., Zoldoš V, Lauc G
Aging (Albany NY) 15 (24) 14509-14552 [2023-12-26; online 2023-12-26]
Clemens Wittenbecher DDLS Fellow
A suicidal and extensively disordered luciferase with a bright luminescence
Dijkema FM, Escarpizo-Lorenzana MI, Nordentoft MK, ..., Teilum K, Winther JR
- - (-) - [2023-12-22; online 2023-12-22]
Cell Stress 7 (12) - [2023-12-22; online 2023-12-22]
Translational mapping of spatially resolved transcriptomes in human and mouse pulmonary fibrosis
Franzén L, Lindvall MO, Hühn M, ..., Ståhl PL, Hornberg JJ
- - (-) - [2023-12-21; online 2023-12-21]
A machine learning and live-cell imaging tool kit uncovers small molecules induced phospholipidosis.
Hu H, Tjaden A, Knapp S, Antolin AA, Müller S
Cell Chem Biol 30 (12) 1634-1651.e6 [2023-12-21; online 2023-10-04]
Evaluation of noninvasive biospecimens for transcriptome studies.
Martorella M, Kasela S, Garcia-Flores R, ..., Castel SE, Lappalainen T
BMC Genomics 24 (1) 790 [2023-12-19; online 2023-12-19]
Author Response: Association of genetic variation in COL11A1 with adolescent idiopathic scoliosis
Yu H, Khanshour AM, Ushiki A, ..., Ahituv N, Wise CA
- - (-) - [2023-12-19; online 2023-12-19]
Association of genetic variation in COL11A1 with adolescent idiopathic scoliosis
Yu H, Khanshour AM, Ushiki A, ..., Ahituv N, Wise CA
- - (-) - [2023-12-19; online 2023-12-19]
Improved detection of clinically relevant fusion transcripts in cancer by machine learning classification.
Hafstað V, Häkkinen J, Larsson M, ..., Vallon-Christersson J, Persson H
BMC Genomics 24 (1) 783 [2023-12-18; online 2023-12-18]
Spatial, temporal and numerical regulation of polar flagella assembly in Pseudomonas putida
Pulido-Sánchez M, Leal-Morales A, López-Sánchez A, Cava F, Govantes F
- - (-) - [2023-12-15; online 2023-12-15]
Influenza-A mediated pre-existing immunity levels to SARS-CoV-2 could predict early COVID-19 outbreak dynamics.
Almazán NM, Rahbar A, Carlsson M, ..., Sörensen B, Söderberg-Nauclér C
iScience 26 (12) 108441 [2023-12-15; online 2023-11-14]
The complex nature of lncRNA-mediated chromatin dynamics in multiple myeloma.
Nylund P, Garrido-Zabala B, Kalushkova A, Wiklund HJ
Front Oncol 13 (-) 1303677 [2023-12-11; online 2023-12-11]
Novel data-driven subtypes and stages of brain atrophy in the ALS-FTD spectrum.
Shen T, Vogel JW, Duda J, ..., Irwin DJ, McMillan CT
Transl Neurodegener 12 (1) 57 [2023-12-07; online 2023-12-07]
Increasing diversity of functional genetics studies to advance biological discovery and human health.
George SHL, Medina-Rivera A, Idaghdour Y, Lappalainen T, Gallego Romero I
Am. J. Hum. Genet. 110 (12) 1996-2002 [2023-12-07; online 2023-11-22]
Experimental design of blending samples to increase precision of 1H NMR urine metabolomics
Bay Nord A, Lindqvist H, Rådjursöga M, ..., Karlsson G, Malmodin D
- - (-) - [2023-12-07; online 2023-12-07]
Experimental design of blending samples to increase precision of 1H NMR urine metabolomics
Bay Nord A, Lindqvist H, Rådjursöga M, ..., Karlsson G, Malmodin D
- - (-) - [2023-12-06; online 2023-12-06]
Experimental design of blending samples to increase precision of 1H NMR urine metabolomics
Bay Nord A, Lindqvist H, Rådjursöga M, ..., Karlsson G, Malmodin D
- - (-) - [2023-12-06; online 2023-12-06]
Copy number variations and their effect on the plasma proteome.
Schmitz D, Li Z, Lo Faro V, ..., Rafati N, Johansson Å
Genetics 225 (4) - [2023-12-06; online 2023-10-04]
Spatially resolved molecular and cellular atlas of the mouse brain
Han L, Liu Z, Jing Z, ..., Wei W, Sun YG
- - (-) - [2023-12-05; online 2023-12-05]
Extensive remodelling of XIST regulatory networks during primate evolution
Cazottes E, Alfeghaly C, Rognard C, ..., Morey C, Rougeulle C
- - (-) - [2023-12-04; online 2023-12-04]
A surfactant lipid layer of endosomal membranes facilitates airway gas filling in Drosophila.
Tsarouhas V, Liu D, Tsikala G, ..., Strigini M, Samakovlis C
Curr. Biol. 33 (23) 5132-5146.e5 [2023-12-04; online 2023-11-21]
Inputs, amplification and sinks of perfluoroalkyl substances at coastal Antarctica.
Casas G, Iriarte J, D'Agostino LA, ..., Jiménez B, Dachs J
Environ Pollut 338 (-) 122608 [2023-12-01; online 2023-09-22]
Infectivity of exhaled SARS-CoV-2 aerosols is sufficient to transmit covid-19 within minutes.
Alsved M, Nyström K, Thuresson S, ..., Medstrand P, Löndahl J
Sci Rep 13 (1) 21245 [2023-12-01; online 2023-12-01]
Utilizing CD44v6 and V600EBRAF-mutation for in vitro targeted combination therapy of thyroid carcinomas.
Mortensen ACL, Imgenberg-Kreuz J, Spiegelberg D, Botling J, Nestor M
Heliyon 9 (12) e22594 [2023-12-00; online 2023-11-20]
Songbird germline-restricted chromosome as a potential arena of genetic conflicts.
Vontzou N, Pei Y, Mueller JC, ..., Schlebusch SA, Suh A
Curr. Opin. Genet. Dev. 83 (-) 102113 [2023-12-00; online 2023-09-19]
Proteomics Analysis Identifying New Markers Related to Alzheimer’s Disease Pathology In Vivo
Binette AP, Salvadó G, Spotorno N, ..., Janelidze S, Hansson O
Alzheimers Dement 19 (S14) - [2023-12-00; online 2023-12-25]
Novel CSF tau biomarkers can be used for disease staging of sporadic Alzheimer’s
Salvadó G, Horie K, Barthélemy NR, ..., Bateman RJ, Hansson O
Alzheimers Dement 19 (S14) - [2023-12-00; online 2023-12-25]
NAD+ regulates nucleotide metabolism and genomic DNA replication.
Munk SHN, Merchut-Maya JM, Adelantado Rubio A, ..., Bartek J, Maya-Mendoza A
Nat. Cell Biol. 25 (12) 1774-1786 [2023-12-00; online 2023-11-13]
Ki67 and prostate specific antigen are prognostic in metastatic hormone naïve prostate cancer.
Spyratou V, Freyhult E, Bergh A, ..., Welén K, Josefsson A
Acta Oncol 62 (12) 1698-1706 [2023-12-00; online 2023-09-15]
High-throughput cell spheroid production and assembly analysis by microfluidics and deep learning.
Trossbach M, Åkerlund E, Langer K, Seashore-Ludlow B, Joensson HN
SLAS Technol 28 (6) 423-432 [2023-12-00; online 2023-03-28]
Growth or death? Control of cell destiny by mTOR and autophagy pathways.
Khalil MI, Ali MM, Holail J, Houssein M
Prog. Biophys. Mol. Biol. 185 (-) 39-55 [2023-12-00; online 2023-11-08]
Engineered organoids for biomedical applications.
Roberto de Barros N, Wang C, Maity S, ..., Kim HJ, Khademhosseini A
Adv. Drug Deliv. Rev. 203 (-) 115142 [2023-12-00; online 2023-11-13]
Both C57BL/KsJ (H2d haplotype) and CB10-H2 (H2b haplotype) mice are highly susceptible to congenital toxoplasmosis.
Coutinho LB, de Oliveira MC, Araujo ECB, ..., Czarnewski P, Silva NM
Acta Trop 248 (-) 107022 [2023-12-00; online 2023-09-15]
Advances in genome-scale metabolic models of industrially important fungi.
Han Y, Tafur Rangel A, Pomraning KR, Kerkhoven EJ, Kim J
Curr. Opin. Biotechnol. 84 (-) 103005 [2023-12-00; online 2023-10-03]
A versatile method for the identification of senolytic compounds.
Annunziata C, Castoldi F, Jan S, ..., Riedel CG, Pietrocola F
Cell Stress 7 (12) 105-111 [2023-12-00; online 2023-12-11]
A STRP-ed definition of Structured Tandem Repeats in Proteins.
Monzon AM, Arrías PN, Elofsson A, ..., Kajava AV, Tosatto SCE
J. Struct. Biol. 215 (4) 108023 [2023-12-00; online 2023-08-29]
Author Response: Association of genetic variation in COL11A1 with adolescent idiopathic scoliosis
Yu H, Khanshour AM, Ushiki A, ..., Ahituv N, Wise CA
- - (-) - [2023-11-30; online 2023-11-30]
Association of genetic variation in COL11A1 with adolescent idiopathic scoliosis
Yu H, Khanshour AM, Ushiki A, ..., Ahituv N, Wise CA
- - (-) - [2023-11-30; online 2023-11-30]
Ovarian ERβ cistrome and transcriptome reveal chromatin interaction with LRH-1.
Birgersson M, Indukuri R, Lindquist L, ..., Archer A, Williams C
BMC Biol. 21 (1) 277 [2023-11-29; online 2023-11-29]
Improved production of Taxol® precursors in S. cerevisiae using combinatorial in silico design and metabolic engineering.
Malcı K, Santibáñez R, Jonguitud-Borrego N, ..., Kerkhoven EJ, Rios-Solis L
Microb Cell Fact 22 (1) 243 [2023-11-29; online 2023-11-29]
Single-cell transcriptomics of human traumatic brain injury reveals activation of endogenous retroviruses in oligodendroglia.
Garza R, Sharma Y, Atacho DAM, ..., Jakobsson J, Marklund N
Cell Reports 42 (11) 113395 [2023-11-28; online 2023-11-14]
Chromatin insulation orchestrates matrix metalloproteinase gene cluster expression reprogramming in aggressive breast cancer tumors.
Llinàs-Arias P, Ensenyat-Mendez M, Íñiguez-Muñoz S, ..., Lupien M, Marzese DM
Mol Cancer 22 (1) 190 [2023-11-28; online 2023-11-28]
Autophagy-mediated control of ribosome homeostasis in oncogene-induced senescence.
López AR, Jørgensen MH, Havelund JF, ..., Happonen L, Frankel LB
Cell Reports 42 (11) 113381 [2023-11-28; online 2023-11-05]
Affibody-based hBCMA x CD16 dual engagers for NK cell-mediated killing of multiple myeloma cells.
Giang KA, Boxaspen T, Diao Y, ..., Malmberg KJ, Nygren PÅ
N Biotechnol 77 (-) 139-148 [2023-11-25; online 2023-09-04]
Selection, characterization and in vivo evaluation of novel CD44v6-targeting antibodies for targeted molecular radiotherapy.
Mortensen ACL, Berglund H, Segerström L, ..., Frejd FY, Nestor M
Sci Rep 13 (1) 20648 [2023-11-24; online 2023-11-24]
Association of genetic variation in COL11A1 with adolescent idiopathic scoliosis.
Yu H, Khanshour AM, Ushiki A, ..., Ahituv N, Wise CA
bioRxiv - (-) - [2023-11-22; online 2023-11-22]
FAIR+E pathogen data for surveillance and research: lessons from COVID-19.
Neves A, Cuesta I, Hjerde E, ..., Waheed Z, Blomberg N
Front Public Health 11 (-) 1289945 [2023-11-21; online 2023-11-21]
Mitotic MTH1 Inhibitors in Treatment of Cancer.
Helleday T
Cancer Treat Res 186 (-) 223-237 [2023-11-18; online 2023-11-18]
Pooled optical screening in bacteria using chromosomally expressed barcodes
Soares RRG, García-Soriano DA, Larsson J, ..., Nilsson M, Elf J
- - (-) - [2023-11-17; online 2023-11-17]
Factors driving PPCPs uptake by crops after wastewater irrigation and human health implications.
Sunyer-Caldú A, Quintana G, Diaz-Cruz MS
Environ. Res. 237 (Pt 1) 116923 [2023-11-15; online 2023-08-19]
Associations between the chemical exposome and pregnancy induced hypertension.
Soomro MH, England-Mason G, Liu J, ..., Dewey D, APrON Study Team
Environ. Res. 237 (Pt 1) 116838 [2023-11-15; online 2023-08-05]
Altered plasma protein profiles in genetic FTD - a GENFI study.
Ullgren A, Öijerstedt L, Olofsson J, ..., Graff C, Genetic Frontotemporal Dementia Initiative (GENFI)
Mol Neurodegener 18 (1) 85 [2023-11-15; online 2023-11-15]
TMIC-57. CHARTING THE SPATIAL ARCHITECTURE OF GLIOBLASTOMA USING GBMAP: INSIGHTS FROM IN SITU SEQUENCING
Ruiz C, Marco-Salas S, Samuelsson E, ..., Nilsson M, Stunnenberg H
Neuro-oncology 25 (Supplement_5) v291-v291 [2023-11-10; online 2023-11-10]
Core genes driving climate adaptation in plants
Yeaman S, Whiting J, Booker T, ..., Wright S, Zhou L
- - (-) - [2023-11-10; online 2023-11-10]
Pascal Milesi SciLifeLab Fellow
Demographic and genetic factors shape the epitope specificity of the human antibody repertoire against viruses
Olin A, Jaquaniello A, Roux M, ..., Quintana-Murci L, Patin E
- - (-) - [2023-11-08; online 2023-11-08]
The roles of surround inhibition for the intrinsic function of the striatum, analyzed in silico.
Frost Nylén J, Hjorth JJJ, Kozlov A, ..., Hellgren Kotaleski J, Grillner S
Proc. Natl. Acad. Sci. U.S.A. 120 (45) e2313058120 [2023-11-07; online 2023-11-03]
coRIC map: a framework for the exploration of multifaceted subcellular RNA-binding proteins
Lv Y, Guo X, Hu J, ..., Zhang X, Esteban MA
- - (-) - [2023-11-06; online 2023-11-06]
Enhancers dysfunction in the 3D genome of cancer cells.
Della Chiara G, Jiménez C, Virdi M, Crosetto N, Bienko M
Front Cell Dev Biol 11 (-) 1303862 [2023-11-06; online 2023-11-06]
Magda Bienko SciLifeLab Fellow
The Role of Small Nucleolar RNAs As Putative Biomarkers of Chemoresistance in Pediatric Acute Lymphoblastic Leukemia
Krali O, Enblad AP, Blom K, ..., Lönnerholm G, Nordlund J
Blood 142 (Supplement 1) 6064-6064 [2023-11-02; online 2023-11-02]
Mapping Chemo-Resistance Profiles of Pediatric Acute Leukemia through Integration of Ex-Vivo Drug Screens with Molecular Data
Enblad AP, Krali O, Blom K, ..., Lönnerholm G, Nordlund J
Blood 142 (Supplement 1) 1449-1449 [2023-11-02; online 2023-11-02]
Gut Microbial Dysbiosis in Myeloid Neoplasms: Correlations with Clinical and Genomic Features
Portlock T, Campagna A, Viviani F, ..., Della Porta MG, Shoaie S
Blood 142 (Supplement 1) 3216-3216 [2023-11-02; online 2023-11-02]
Saeed Shoaie SciLifeLab Fellow
Genomic Determinants of Therapy Response in ETV6::RUNX1 Leukemia
Oksa L, Moisio S, Maqbool K, ..., Lohi O, Heinäniemi M
Blood 142 (Supplement 1) 2970-2970 [2023-11-02; online 2023-11-02]
Epigenetic Profiling and Machine Learning for Enhanced Risk Stratification in Pediatric Acute Lymphoblastic Leukemia
Mosquera Orgueira A, Krali O, Peleteiro Raindo A, ..., Schmiegelow K, Nordlund J
Blood 142 (Supplement 1) 4353-4353 [2023-11-02; online 2023-11-02]
3-D chromatin conformation, accessibility, and gene expression profiling of triple-negative breast cancer.
Llinàs-Arias P, Ensenyat-Méndez M, Orozco JIJ, ..., Lupien M, Marzese DM
BMC Genom Data 24 (1) 61 [2023-11-02; online 2023-11-02]
Structure and dynamics of differential ligand binding in the human ρ-type GABAA receptor.
Cowgill J, Fan C, Haloi N, ..., Howard RJ, Lindahl E
Neuron 111 (21) 3450-3464.e5 [2023-11-01; online 2023-09-01]
Demographic reconstruction of the Western sheep expansion from whole-genome sequences.
Morell Miranda P, Soares AER, Günther T
G3 13 (11) - [2023-11-01; online 2023-09-07]
The evolution of intramitochondriality in Midichloria bacteria.
Floriano AM, Batisti Biffignandi G, Castelli M, ..., Guy L, Sassera D
Environ. Microbiol. 25 (11) 2102-2117 [2023-11-00; online 2023-06-12]
Synthesis, Anti-inflammatory, and Neuroprotective Activity of N-Substituted Phthalimide Derivatives
Bhat MA, Ahmed AF, Wen ZH, ..., Naglah AM, Al-Omar MA
Russ J Gen Chem 93 (11) 2935-2940 [2023-11-00; online 2023-12-21]
Proline catabolism is a key factor facilitating Candida albicans pathogenicity.
Silao FGS, Jiang T, Bereczky-Veress B, ..., Peuckert C, Ljungdahl PO
PLoS Pathog 19 (11) e1011677 [2023-11-00; online 2023-11-02]
Monoclonal antibodies lock down SARS-CoV-2 spike.
Huang HC, Angeletti D
Trends Immunol. 44 (11) 874-876 [2023-11-00; online 2023-10-05]
Leveraging circulating microbial DNA for early cancer detection.
Kataria R, Shoaie S, Grigoriadis A, Wan JCM
Trends Cancer 9 (11) 879-882 [2023-11-00; online 2023-09-01]
Saeed Shoaie SciLifeLab Fellow
VLDLR mediates alphavirus neuroinvasion through the blood-cerebrospinal fluid barrier
Martikainen M, Lugano R, Pietilä I, ..., Dimberg A, Essand M
- - (-) - [2023-10-30; online 2023-10-30]
Editorial: Understanding membrane transporters: from structure to function.
Pasquadibisceglie A, Bonaccorsi Di Patti MC, Miniero DV, Musci G, Polticelli F
Front Mol Biosci 10 (-) 1323824 [2023-10-30; online 2023-10-30]
Of mice and lymphoid aggregates: modeling tertiary lymphoid structures in cancer.
Vaccaro A, van de Walle T, Ramachandran M, Essand M, Dimberg A
Front Immunol 14 (-) 1275378 [2023-10-26; online 2023-10-26]
Multi-omics Quality Assessment in Personalized Medicine through EATRIS
Alonso-Andrés P, Baldazzi D, Chen Q, ..., Zheng Y, Žižkovičová P
- - (-) - [2023-10-26; online 2023-10-26]
Discovery of a novel inhibitor of macropinocytosis with antiviral activity
Porebski B, Christ W, Corman A, ..., Huhn D, Fernandez-Capetillo O
- - (-) - [2023-10-26; online 2023-10-26]
Erdinc Sezgin SciLifeLab Fellow
Correction: Local excision versus thrombectomy in thrombosed external hemorrhoids: a multicenter, prospective, observational study.
Yalcinkaya A, Yalcinkaya A, Atici SD, ..., Leventoglu S, T E H Study Collaboration
BMC Surg 23 (1) 321 [2023-10-24; online 2023-10-24]
Molecular and spatial landmarks of early mouse skin development.
Jacob T, Annusver K, Czarnewski P, ..., Björklund ÅK, Kasper M
Dev. Cell 58 (20) 2140-2162.e5 [2023-10-23; online 2023-08-16]
Editorial: Lymphatic system: organ specific functions in health and disease.
Koltowska K, Jakus Z, Hong YK, Kume T
Front Cell Dev Biol 11 (-) 1224584 [2023-10-23; online 2023-10-23]
FBXL12 degrades FANCD2 to regulate replication recovery and promote cancer cell survival under conditions of replication stress.
Brunner A, Li Q, Fisicaro S, ..., Orre LM, Sangfelt O
Mol. Cell 83 (20) 3720-3739.e8 [2023-10-19; online 2023-08-16]
Editorial: Computational methods for pain pharmacology.
Mlost J, Kucharczyk M
Front Pain Res (Lausanne) 4 (-) 1298882 [2023-10-19; online 2023-10-19]
Automated model building and protein identification in cryo-EM maps.
Jamali K, Käll L, Zhang R, ..., Kimanius D, Scheres SHW
bioRxiv - (-) - [2023-10-17; online 2023-10-17]
Endothelial VEGFR2-PLCγ signaling regulates vascular permeability and antitumor immunity through eNOS/Src.
Sjöberg E, Melssen M, Richards M, ..., Dimberg A, Claesson-Welsh L
J. Clin. Invest. 133 (20) - [2023-10-16; online 2023-10-16]
Comment on bg-2023-147
- - (-) - [2023-10-16; online 2023-10-16]
Genomic, transcriptomic and epigenomic sequencing data of the B-cell leukemia cell line REH.
Lysenkova Wiklander M, Övernäs E, Lagensjö J, ..., Liljedahl U, Nordlund J
BMC Res Notes 16 (1) 265 [2023-10-10; online 2023-10-10]
Genetic ablation of adhesion ligands averts rejection of allogeneic immune cells.
Hammer Q, Perica K, van Ooijen H, ..., Sadelain M, Malmberg KJ
bioRxiv - (-) - [2023-10-09; online 2023-10-09]
Bacterial cell surface nanoenvironment requires a specialized chaperone to activate a peptidoglycan biosynthetic enzyme.
Delerue T, Chareyre S, Anantharaman V, ..., Aravind L, Ramamurthi KS
bioRxiv - (-) - [2023-10-06; online 2023-10-06]
Mitochondrial heteroplasmic shifts reveal a positive selection of breast cancer.
Li Y, Sundquist K, Vats S, ..., Sundquist J, Memon AA
J Transl Med 21 (1) 696 [2023-10-05; online 2023-10-05]
Comment on bg-2023-147
- - (-) - [2023-10-05; online 2023-10-05]
A fluorophore-conjugated reagent enabling rapid detection, isolation and live tracking of senescent cells.
Magkouta S, Veroutis D, Pousias A, ..., Evangelou K, Gorgoulis VG
Mol. Cell 83 (19) 3558-3573.e7 [2023-10-05; online 2023-10-07]
The long non-coding RNA LINC00707 interacts with Smad proteins to regulate TGFβ signaling and cancer cell invasion.
Gélabert C, Papoutsoglou P, Golán I, ..., Caja L, Moustakas A
Cell Commun. Signal 21 (1) 271 [2023-10-02; online 2023-10-02]
Well-being spectrum traits are associated with polygenic scores for autism.
Mohammad S, de Ruijter MJT, Rukh G, ..., Mwinyi J, Schiöth HB
Autism Res 16 (10) 1891-1902 [2023-10-00; online 2023-08-21]
The dynamics of touch-responsive gene expression in cereals.
Darwish E, Ghosh R, Bentzer J, ..., Sirijovski N, Van Aken O
Plant J. 116 (1) 282-302 [2023-10-00; online 2023-06-08]
SPP1/osteopontin: a driver of fibrosis and inflammation in degenerative ascending aortic aneurysm?
Freiholtz D, Bergman O, Pradhananga S, ..., Eriksson P, Björck HM
J. Mol. Med. 101 (10) 1323-1333 [2023-10-00; online 2023-09-12]
SARS-CoV-2-related mortality decrease in nursing home residents given multiple COVID-19 boosters.
Blom K, Fjällström P, Molnár C, ..., Forsell MNE, Johansson AF
Lancet Infect Dis 23 (10) e393-e394 [2023-10-00; online 2023-09-13]
Quantification of proteomic profile changes in the hemolymph of crayfish during in vitro coagulation.
Mengal K, Kor G, Siino V, ..., Levander F, Niksirat H
Dev. Comp. Immunol. 147 (-) 104760 [2023-10-00; online 2023-06-16]
Precision medicine in rare diseases: What is next?
Tesi B, Boileau C, Boycott KM, ..., Nordgren A, Lindstrand A
J. Intern. Med. 294 (4) 397-412 [2023-10-00; online 2023-06-01]
Precision cancer medicine: Concepts, current practice, and future developments.
Edsjö A, Holmquist L, Geoerger B, ..., Siu LL, Stenzinger A
J. Intern. Med. 294 (4) 455-481 [2023-10-00; online 2023-08-28]
Origin matters: Using a local reference genome improves measures in population genomics.
Thorburn DJ, Sagonas K, Binzer-Panchal M, ..., Lenz TL, Eizaguirre C
Mol Ecol Resour 23 (7) 1706-1723 [2023-10-00; online 2023-07-25]
On the Path to Optimal Alchemistry.
Lundborg M, Lidmar J, Hess B
Protein J 42 (5) 477-489 [2023-10-00; online 2023-08-31]
Methods to Discover and Validate Biofluid-Based Biomarkers in Neurodegenerative Dementias.
Teunissen CE, Kimble L, Bayoumy S, ..., Zetterberg H, MIRIADE consortium
Mol. Cell Proteomics 22 (10) 100629 [2023-10-00; online 2023-08-07]
Distinct HLA associations with autoantibody-defined subgroups in idiopathic inflammatory myopathies.
Leclair V, Galindo-Feria AS, Rothwell S, ..., Lundberg IE, Diaz-Gallo LM
EBioMedicine 96 (-) 104804 [2023-10-00; online 2023-09-26]
Whole genome sequence of the deep-sea sponge Geodia barretti (Metazoa, Porifera, Demospongiae).
Steffen K, Proux-Wéra E, Soler L, ..., Sundh J, Cárdenas P
G3 13 (10) - [2023-09-30; online 2023-08-25]
Exploring the morphology of the host cell to open new possibilities for drug repurposing in viral infections
Tampere M, Kalman A, Rietdijk J, ..., Stadler C, Östling P
- - (-) - [2023-09-28; online 2023-09-28]
Association of an estrogen-sensitive Pax1-Col11a1-Mmp3 signaling axis with adolescent idiopathic scoliosis
Yu H, Khanshour AM, Ushiki A, ..., Ahituv N, Wise CA
- - (-) - [2023-09-27; online 2023-09-27]
The draft genome of the microscopic Nemertoderma westbladi sheds light on the evolution of Acoelomorpha genomes.
Abalde S, Tellgren-Roth C, Heintz J, Vinnere Pettersson O, Jondelius U
Front Genet 14 (-) 1244493 [2023-09-26; online 2023-09-26]
The microbial biodiversity at the archeological site of Tel Megiddo (Israel).
Zhang Y, Ruff SE, Oskolkov N, ..., Mason CE, Elhaik E
Front Microbiol 14 (-) 1253371 [2023-09-22; online 2023-09-22]
Non-classical HLA-E restricted CMV 15-mer peptides are recognized by adaptive NK cells and induce memory responses.
Martín Almazán N, Sala BM, Sandalova T, ..., Achour A, Sarhan D
Front Immunol 14 (-) 1230718 [2023-09-21; online 2023-09-21]
Building the next generation of virtual cells to understand cellular biology.
Johnson GT, Agmon E, Akamatsu M, ..., Rafelski S, Horwitz R
Biophys. J. 122 (18) 3560-3569 [2023-09-19; online 2023-04-11]
DDLS Fellow Wei Ouyang
Epigenetic coordination of transcriptional and translational programs in hypoxia
Watt K, Dauber B, Szkop KJ, ..., Larsson O, Postovit LM
- - (-) - [2023-09-17; online 2023-09-17]
Enhancing European capabilities for application of multi-omics studies in biology and biomedicine space research.
Manzano A, Weging S, Bezdan D, ..., da Silveira WA, Herranz R
iScience 26 (9) 107289 [2023-09-15; online 2023-07-12]
Genetic atlas of hygro-and thermosensory cells in the vinegar fly Drosophila melanogaster.
Corthals K, Andersson V, Churcher A, Reimegård J, Enjin A
Sci Rep 13 (1) 15202 [2023-09-14; online 2023-09-14]
Identifying genetic regulatory variants that affect transcription factor activity.
Li X, Lappalainen T, Bussemaker HJ
Cell Genom 3 (9) 100382 [2023-09-13; online 2023-08-18]
Merging Multi-OMICs with Proteome Integral Solubility Alteration Unveils Antibiotic Mode of Action
Maity R, Zhang X, Liberati FR, ..., Aínsa JA, Sancho J
- - (-) - [2023-09-11; online 2023-09-11]
A novel kleptoplastidic symbiosis revealed in the marine centrohelid Meringosphaera with evidence of genetic integration.
Sørensen MES, Zlatogursky VV, Onuţ-Brännström I, ..., Foster RA, Burki F
Curr. Biol. 33 (17) 3571-3584.e6 [2023-09-11; online 2023-08-02]
Fabien Burki SciLifeLab Fellow
Hippo-deficient cardiac fibroblasts differentiate into osteochondroprogenitors.
Tsai CR, Kim J, Li X, ..., Samee MAH, Martin J
bioRxiv - (-) - [2023-09-08; online 2023-09-08]
Continental scientific drilling and microbiology: (extremely) low biomass in crystalline bedrock of central Sweden
Westmeijer G, Escudero C, Bergin C, ..., Bertilsson S, Dopson M
- - (-) - [2023-09-07; online 2023-09-07]
Advanced variant classification framework reduces the false positive rate of predicted loss-of-function variants in population sequencing data.
Singer-Berk M, Gudmundsson S, Baxter S, ..., Rehm HL, O'Donnell-Luria A
Am. J. Hum. Genet. 110 (9) 1496-1508 [2023-09-07; online 2023-08-25]
A test of memory for stimulus sequences in great apes.
Lind J, Vinken V, Jonsson M, Ghirlanda S, Enquist M
PLoS ONE 18 (9) e0290546 [2023-09-06; online 2023-09-06]
Parkin is not required to sustain OXPHOS function in adult mammalian tissues
Filograna R, Gerlach J, Choi HN, ..., Svenningsson P, Larsson NG
- - (-) - [2023-09-02; online 2023-09-02]
The Genomic Basis of Adaptation to High Elevations in Africanized Honey Bees.
Everitt T, Wallberg A, Christmas MJ, ..., Neumann P, Webster MT
Genome Biol Evol 15 (9) - [2023-09-01; online 2023-08-26]
Stratified genetic analysis reveals sex differences in MPO-ANCA-associated vasculitis.
Ekman D, Sennblad B, Knight A, ..., Lindblad-Toh K, Dahlqvist J
Rheumatology (Oxford) 62 (9) 3213-3218 [2023-09-01; online 2023-04-03]
Multifaceted proteome analysis at solubility, redox, and expression dimensions for target identification
Saei AA, Lundin A, Lyu H, ..., Gygi SP, Zubarev RA
- - (-) - [2023-09-01; online 2023-09-01]
Influenza virus decreases albumin uptake and megalin expression in alveolar epithelial cells.
Alberro-Brage A, Kryvenko V, Malainou C, ..., Samakovlis C, Vadász I
Front Immunol 14 (-) 1260973 [2023-09-01; online 2023-09-01]
Whole tumour cell-based vaccines: tuning the instruments to orchestrate an optimal antitumour immune response.
Pérez-Baños A, Gleisner MA, Flores I, ..., Tittarelli A, Salazar-Onfray F
Br. J. Cancer 129 (4) 572-585 [2023-09-00; online 2023-06-24]
The understory microclimate in agroforestry now and in the future – a case study of Arabica coffee in its native range
Zignol F, Kjellström E, Hylander K, ..., Rodríguez-Gijón A, Tack AJM
Agricultural and Forest Meteorology 340 (-) 109586 [2023-09-00; online 2023-09-00]
Immune system adaptation during gender-affirming testosterone treatment
Consiglio C, Tadepally L, Sardh F, ..., Landegren N, Brodin P
Journal of Reproductive Immunology 159 (-) 104065 [2023-09-00; online 2023-09-00]
Camila Consiglio DDLS Fellow
GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification.
Lagou V, Jiang L, Ulrich A, ..., Prokopenko I, Meta-Analysis of Glucose and Insulin-Related Traits Consortium (MAGIC)
Nat. Genet. 55 (9) 1448-1461 [2023-09-00; online 2023-09-07]
Ex Vivo Drug Testing in Patient-derived Papillary Renal Cancer Cells Reveals EGFR and the BCL2 Family as Therapeutic Targets.
Angori S, Banaei-Esfahani A, Mühlbauer K, ..., Schraml P, Moch H
Eur Urol Focus 9 (5) 751-759 [2023-09-00; online 2023-03-16]
Image-based and machine learning-guided multiplexed serology test for SARS-CoV-2.
Pietiäinen V, Polso M, Migh E, ..., Horvath P, Hepojoki J
Cell Rep Methods 3 (8) 100565 [2023-08-28; online 2023-08-22]
Padlock Probe-Based Targeted In Situ Sequencing: Overview of Methods and Applications.
Magoulopoulou A, Salas SM, Tiklová K, ..., Hilscher MM, Nilsson M
Annu Rev Genomics Hum Genet 24 (-) 133-150 [2023-08-25; online 2023-04-05]
Long-read whole-genome analysis of human single cells.
Hård J, Mold JE, Eisfeldt J, ..., Michaëlsson J, Ameur A
Nat Commun 14 (1) 5164 [2023-08-24; online 2023-08-24]
Highly multiplexed targeted sequencing strategy for infectious disease surveillance.
Hernández-Neuta I, Magoulopoulou A, Pineiro F, ..., Gulberg M, Nilsson M
BMC Biotechnol. 23 (1) 31 [2023-08-23; online 2023-08-23]
Multiple cis -regulatory elements control prox1a expression in distinct lymphatic vascular beds
Panara V, Yu H, Peng D, ..., Hogan BM, Koltowska K
- - (-) - [2023-08-22; online 2023-08-22]
Single-cell spatial transcriptome reveals cell-type organization in the macaque cortex.
Chen A, Sun Y, Lei Y, ..., Xu X, Li C
Cell 186 (17) 3726-3743.e24 [2023-08-17; online 2023-07-12]
Association of the human gut microbiota with vascular stiffness.
Cuadrat RRC, Goris T, Birukov A, ..., Wittenbecher C, Schulze MB
Sci Rep 13 (1) 13348 [2023-08-16; online 2023-08-16]
Clemens Wittenbecher DDLS Fellow
Using evolutionary constraint to define novel candidate driver genes in medulloblastoma.
Roy A, Sakthikumar S, Kozyrev SV, ..., Lindblad-Toh K, Forsberg-Nilsson K
Proc. Natl. Acad. Sci. U.S.A. 120 (33) e2300984120 [2023-08-15; online 2023-08-07]
Illuminating the Function of the Orphan Transporter, SLC22A10 in Humans and Other Primates.
Yee SW, Ferrández-Peral L, Alentorn P, ..., Marques-Bonet T, Giacomini KM
bioRxiv - (-) - [2023-08-12; online 2023-08-12]
Nucleolar stress caused by arginine-rich peptides triggers a ribosomopathy and accelerates ageing in mice
Sirozh O, Jung B, Sanchez-Burgos L, ..., Lafarga V, Fernández-Capetillo O
- - (-) - [2023-08-11; online 2023-08-11]
Local excision versus thrombectomy in thrombosed external hemorrhoids: a multicenter, prospective, observational study.
Yalcinkaya A, Yalcinkaya A, Atici SD, ..., Leventoglu S, T E H Study Collaboration
BMC Surg 23 (1) 228 [2023-08-10; online 2023-08-10]
Multiset correlation and factor analysis enables exploration of multi-omics data.
Brown BC, Wang C, Kasela S, ..., Knowles DA, Lappalainen T
Cell Genom 3 (8) 100359 [2023-08-09; online 2023-07-10]
Folded alpha helical putative new proteins from Apilactobacillus kunkeei
Ye W, Behra PRK, Dyrhage K, ..., Andersson SGE, Jemth P
- - (-) - [2023-08-09; online 2023-08-09]
A novel quantitative targeted analysis of X-chromosome inactivation (XCI) using nanopore sequencing.
Johansson J, Lidéus S, Höijer I, ..., Bondeson ML, Wilbe M
Sci Rep 13 (1) 12856 [2023-08-08; online 2023-08-08]
Technology platform for facile handling of 3D hydrogel cell culture scaffolds.
Pohlit H, Bohlin J, Katiyar N, Hilborn J, Tenje M
Sci Rep 13 (1) 12829 [2023-08-07; online 2023-08-07]
Chylomicrons Regulate Lacteal Permeability and Intestinal Lipid Absorption.
Zarkada G, Chen X, Zhou X, ..., Eichmann A, Zhang F
Circ. Res. 133 (4) 333-349 [2023-08-04; online 2023-07-18]
Multiple Origins and Genomic Basis of Complex Traits in Sighthounds.
Li WL, Liu YH, Li JX, ..., Wang GD, Zhang YP
Mol. Biol. Evol. 40 (8) - [2023-08-03; online 2023-07-11]
Genetic insights into resting heart rate and its role in cardiovascular disease.
van de Vegte YJ, Eppinga RN, van der Ende MY, ..., Verweij N, van der Harst P
Nat Commun 14 (1) 4646 [2023-08-02; online 2023-08-02]
The salivary microbiota is altered in cervical dysplasia patients and influenced by conization.
Wu S, Cheng L, Pennhag AAL, ..., Andersson S, Du J
Imeta 2 (3) e108 [2023-08-00; online 2023-05-12]
The microbiota conditions a gut milieu that selects for wild-type Salmonella Typhimurium virulence.
Gül E, Bakkeren E, Salazar G, ..., Diard M, Hardt WD
PLoS Biol. 21 (8) e3002253 [2023-08-00; online 2023-08-31]
Spatial transcriptomics of human placentas reveal distinct RNA patterns associated with morphology and preeclampsia.
Bhalla N, Franzén L, Scheynius A, ..., Lager S, Ståhl PL
Placenta 139 (-) 213-216 [2023-08-00; online 2023-07-05]
Polygenic risk scores and risk stratification in deep vein thrombosis.
Lo Faro V, Johansson T, Höglund J, Hadizadeh F, Johansson Å
Thromb. Res. 228 (-) 151-162 [2023-08-00; online 2023-06-10]
PB1709: A COMPLETE DIGITAL KARYOTYPE OF THE B-CELL LEUKEMIA REH CELL LINE RESOLVED BY LONG-READ SEQUENCING
Wiklander ML, Arvidsson G, Bunikis I, ..., Ameur A, Nordlund J
Hemasphere 7 (S3) e656876f [2023-08-00; online 2023-08-08]
OSA Is Associated With the Human Gut Microbiota Composition and Functional Potential in the Population-Based Swedish CardioPulmonary bioImage Study.
Baldanzi G, Sayols-Baixeras S, Theorell-Haglöw J, ..., Lindberg E, Fall T
Chest 164 (2) 503-516 [2023-08-00; online 2023-03-15]
N-terminal proteoforms may engage in different protein complexes.
Bogaert A, Fijalkowska D, Staes A, ..., Calderwood MA, Gevaert K
Life Sci. Alliance 6 (8) - [2023-08-00; online 2023-06-14]
Mucosal IgA protects against BQ.1 and BQ.1.1 infection.
Marking U, Bladh O, Havervall S, ..., Klingström J, Thålin C
Lancet Infect Dis 23 (8) e272-e273 [2023-08-00; online 2023-07-12]
Local and Systemic Immunity During Five Vaccinations Against SARS-CoV-2 in Zanubrutinib-Treated Patients With Chronic Lymphocytic Leukemia.
Andersson M, Wu J, Wullimann D, ..., Ingelman-Sundberg HM, Osterborg A
J Hematol 12 (4) 170-175 [2023-08-00; online 2023-08-08]
Exposures to perfluoroalkyl substances and asthma phenotypes in childhood: an investigation of the COPSAC2010 cohort.
Sevelsted A, Pedersen CT, Gürdeniz G, ..., Chawes B, Bisgaard H
EBioMedicine 94 (-) 104699 [2023-08-00; online 2023-07-08]
Expansion spatial transcriptomics.
Fan Y, Andrusivová Ž, Wu Y, ..., Lundeberg J, Wang B
Nat. Methods 20 (8) 1179-1182 [2023-08-00; online 2023-06-22]
Cystathionine gamma-lyase (CTH) inhibition attenuates glioblastoma formation.
Peleli M, Antoniadou I, Rodrigues-Junior DM, ..., Moustakas A, Papapetropoulos A
Redox Biol 64 (-) 102773 [2023-08-00; online 2023-06-05]
Microaerobic degradation of crude oil and long chain alkanes by a new Rhodococcus strain from Gulf of Mexico.
Juárez K, Reza L, Bretón-Deval L, ..., García-Guevara F, Lara P
World J Microbiol Biotechnol 39 (10) 264 [2023-07-29; online 2023-07-29]
Transposable element insertions in 1000 Swedish individuals.
Bilgrav Saether K, Nilsson D, Thonberg H, ..., Eisfeldt J, Lindstrand A
PLoS ONE 18 (7) e0289346 [2023-07-28; online 2023-07-28]
scDual-Seq of Toxoplasma gondii-infected mouse BMDCs reveals heterogeneity and differential infection dynamics.
Hildebrandt F, Mohammed M, Dziedziech A, ..., Henriksson J, Ankarklev J
Front Immunol 14 (-) 1224591 [2023-07-27; online 2023-07-27]
Delineating functional and molecular impact of ex vivo sample handling in precision medicine
Erkers T, Struyf N, Arnroth C, ..., Kallioniemi O, Seashore-Ludlow B
- - (-) - [2023-07-26; online 2023-07-26]
Identification of ATF3 as a novel protective signature of quiescent colorectal tumor cells
Zhang X, Lu X, Zhong L, ..., Chen X, Sjoblom T
- - (-) - [2023-07-24; online 2023-07-24]
A Molecular Basis of Human Brain Connectivity.
Ng B, Tasaki S, Greathouse KM, ..., Gaiteri C, Herskowitz JH
bioRxiv - (-) - [2023-07-24; online 2023-07-24]
FAVIS: Fast and versatile protocol for non-destructive metabarcoding of bulk insect samples.
Iwaszkiewicz-Eggebrecht E, Łukasik P, Buczek M, ..., Ronquist F, Miraldo A
PLoS ONE 18 (7) e0286272 [2023-07-19; online 2023-07-19]
Novel CSF tau biomarkers can be used for disease staging of sporadic Alzheimer's disease.
Salvadó G, Horie K, Barthélemy NR, ..., Bateman RJ, Hansson O
medRxiv - (-) - [2023-07-16; online 2023-07-16]
InParanoiDB 9: Ortholog Groups for Protein Domains and Full-Length Proteins.
Persson E, Sonnhammer ELL
J. Mol. Biol. 435 (14) 168001 [2023-07-15; online 2023-02-09]
The Escherichia coli chromosome moves to the replisome
Gras K, Fange D, Elf J
- - (-) - [2023-07-13; online 2023-07-13]
N-Glycomic Profiling of Microsatellite Unstable Colorectal Cancer.
Ukkola I, Nummela P, Heiskanen A, ..., Kytölä S, Ristimäki A
Cancers (Basel) 15 (14) - [2023-07-11; online 2023-07-11]
Automated simulation-based membrane protein refinement into cryo-EM data.
Yvonnesdotter L, Rovšnik U, Blau C, ..., Howard RJ, Lindahl E
Biophys. J. 122 (13) 2773-2781 [2023-07-11; online 2023-06-05]
A Career in Catalysis: Bernhard Hauer
Nebel BA, Breuer M, Schneider A, ..., Weissenborn MJ, Nestl BM
ACS Catal 13 (13) 8861-8889 [2023-07-07; online 2023-06-20]
Loss of ctnnd2b affects neuronal differentiation and behavior in zebrafish.
Vaz R, Edwards S, Dueñas-Rey A, Hofmeister W, Lindstrand A
Front Neurosci 17 (-) 1205653 [2023-07-03; online 2023-07-03]
Sex-specific microglia state in the Neuroligin-4 knock-out mouse model of autism spectrum disorder.
Guneykaya D, Ugursu B, Logiacco F, ..., Kettenmann H, Wolf SA
Brain Behav. Immun. 111 (-) 61-75 [2023-07-00; online 2023-03-29]
Mucosal immune responses following a fourth SARS-CoV-2 vaccine dose.
Bladh O, Marking U, Havervall S, ..., Klingström J, Thålin C
Lancet Microbe 4 (7) e488 [2023-07-00; online 2023-04-20]
Cannabis-derived products antagonize platinum drugs by altered cellular transport.
Buchtova T, Beresova L, Chroma K, ..., Bartek J, Mistrik M
Biomed. Pharmacother. 163 (-) 114801 [2023-07-00; online 2023-05-01]
Elevated levels of MMP12 sourced from macrophages are associated with poor prognosis in urothelial bladder cancer.
Kerzeli IK, Kostakis A, Türker P, ..., Lord M, Mangsbo SM
BMC Cancer 23 (1) 605 [2023-06-30; online 2023-06-30]
Interaction molecular QTL mapping discovers cellular and environmental modifiers of genetic regulatory effects.
Kasela S, Aguet F, Kim-Hellmuth S, ..., Graham Barr R, Lappalainen T
bioRxiv - (-) - [2023-06-29; online 2023-06-29]
In vitro models to study natural killer cell dynamics in the tumor microenvironment.
Carannante V, Wiklund M, Önfelt B
Front Immunol 14 (-) 1135148 [2023-06-28; online 2023-06-28]
Persistent immunosuppressive effects of dibutyl phthalate exposure in adult male mice.
Pierozan P, Källsten L, Theodoropoulou E, Almamoun R, Karlsson O
Sci. Total Environ. 878 (-) 162741 [2023-06-20; online 2023-03-11]
Oskar Karlsson SciLifeLab Fellow
Loss of chromosome Y in regulatory T cells
Mattisson J, Halvardson J, Davies H, ..., Dumanski JP, Forsberg LA
- - (-) - [2023-06-20; online 2023-06-20]
Letter to the editor.
Soussi T
Hum. Mol. Genet. 32 (13) 2121-2123 [2023-06-19; online 2023-03-11]
Microbial Profiling of Amniotic Fluid, Umbilical Blood and Placenta of the Foaling Mare.
Hemberg E, Niazi A, Guo Y, ..., Morrell JM, Kútvölgyi G
Animals (Basel) 13 (12) - [2023-06-18; online 2023-06-18]
Disease phenotype prediction in multiple sclerosis.
Herman S, Arvidsson McShane S, Zjukovskaja C, ..., Spjuth O, Kultima K
iScience 26 (6) 106906 [2023-06-16; online 2023-05-19]
N-Glycomic Profiling of Microsatellite Unstable Colorectal Cancer
Ukkola I, Nummela P, Heiskanen A, ..., Kytölä S, Ristimäki A
- - (-) - [2023-06-14; online 2023-06-14]
Zfp697 is an RNA-binding protein that regulates skeletal muscle inflammation and regeneration.
Correia JC, Jannig PR, Gosztyla ML, ..., Yeo GW, Ruas JL
bioRxiv - (-) - [2023-06-13; online 2023-06-13]
Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma.
Ramachandran M, Vaccaro A, van de Walle T, ..., Essand M, Dimberg A
Cancer Cell 41 (6) 1134-1151.e10 [2023-06-12; online 2023-05-11]
Population-based cohort study of oral contraceptive use and risk of depression.
Johansson T, Vinther Larsen S, Bui M, ..., Karlsson T, Johansson Å
Epidemiol Psychiatr Sci 32 (-) e39 [2023-06-12; online 2023-06-12]
Adiposity and sex-specific cancer risk.
Rask-Andersen M, Ivansson E, Höglund J, ..., Karlsson T, Johansson Å
Cancer Cell 41 (6) 1186-1197.e4 [2023-06-12; online 2023-06-14]
Mutations in the CYP27B1 gene cause vitamin D dependent rickets in pugs.
Rohdin C, Wang C, Brander G, ..., Ljungvall I, Lindblad-Toh K
J. Vet. Intern. Med. 37 (4) 1507-1513 [2023-06-09; online 2023-06-09]
Adipokines and risk of rheumatoid arthritis: A two-sample multivariable Mendelian randomisation study.
Vasileiadis GK, Sayols S, Zhao SS, Fatima T, Maglio C
PLoS ONE 18 (6) e0286981 [2023-06-09; online 2023-06-09]
Deconvolution of spatial sequencing provides accurate characterization of hESC-derived DA transplants in vivo.
Rájová J, Davidsson M, Avallone M, ..., Parmar M, Björklund T
Mol Ther Methods Clin Dev 29 (-) 381-394 [2023-06-08; online 2023-05-04]
Ablation of ZC3H11A causes early embryonic lethality and dysregulation of metabolic processes.
Younis S, Jouneau A, Larsson M, ..., Brochard V, Andersson L
Proc. Natl. Acad. Sci. U.S.A. 120 (23) e2216799120 [2023-06-06; online 2023-05-30]
Temporal transcriptome analysis of the endothelial response to tumour necrosis factor
Struck E, Belova T, Hsieh P, ..., Dusart P, Butler L
- - (-) - [2023-06-05; online 2023-06-05]
Evaluation of plasma Short chain fatty acid levels as markers for Inflammatory bowel disease.
Kiasat A, Rautiainen S, Prast-Nielsen S, ..., Gustafsson UO, Löf Granström A
Scand. J. Gastroenterol. 58 (11) 1246-1252 [2023-06-05; online 2023-06-05]
Abstract A051: The spatial landscape of clonal somatic copy number alterations in benign and malignant prostate epithelia
Erickson A, He M, Berglund E, ..., Lamb AD, Lundeberg J
Cancer Res. 83 (11_Supplement) A051-A051 [2023-06-02; online 2023-06-02]
Reply to: Obsessive-Compulsive Disorder, Tic Disorders, and Early-Life Infections.
Zhang T, Brander G, Isung J, ..., Mataix-Cols D, Fernández de la Cruz L
Biol. Psychiatry 93 (11) e37-e38 [2023-06-01; online 2022-12-09]
Obesity-induced inflammation exacerbates clonal hematopoiesis.
Pasupuleti SK, Ramdas B, Burns SS, ..., Natarajan P, Kapur R
J. Clin. Invest. 133 (11) - [2023-06-01; online 2023-06-01]
Abhishek Niroula DDLS Fellow
Antibody There? Mapping the Human Proteome with Mathias Uhlén
Uhlén M, Lin F
GEN Biotechnology 2 (3) 167-171 [2023-06-01; online 2023-06-19]
The Long Noncoding RNA LINC00958 Is Induced in Psoriasis Epidermis and Modulates Epidermal Proliferation.
Luo L, Pasquali L, Srivastava A, ..., Pivarcsi A, Sonkoly E
J. Invest. Dermatol. 143 (6) 999-1010 [2023-06-00; online 2023-01-12]
Relation of different CSF biosignatures to clinical phenotypes in a memory clinic cohort
Alanko V, Mravinacová S, Kivipelto M, ..., Nilsson P, Sandebring‐Matton A
Alzheimers Dement 19 (S2) - [2023-06-00; online 2023-06-16]
POS1439 DEREGULATION IN ADULT IGA VASCULITIS SKIN AS THE BASIS FOR THE DISCOVERY OF NOVEL SERUM BIOMARKERS
Bajželj M, Hladnik M, Toluay TD, ..., Hocevar A, Lakota K
Ann Rheum Dis 82 (-) 1073 [2023-06-00; online 2023-06-00]
POS1438 ANALYSIS OF THE PLASMA PROTEOME PROVIDES MECHANISTIC INSIGHTS INTO THE PATHOPHYSIOLOGY OF ANCA-ASSOCIATED VASCULITIS
Hellbacher E, Van Hoef V, Johansson A, ..., Rantapää Dahlqvist S, Dahlqvist J
Ann Rheum Dis 82 (-) 1073 [2023-06-00; online 2023-06-00]
POS0603 AUTOANTIBODIES AGAINST A SUBUNIT OF MITOCHONDRIAL RESPIRATORY CHAIN COMPLEX I IN INCLUSION BODY MYOSITIS
Notarnicola A, Hellstrom C, Horuluoglu B, ..., Nilsson P, Lundberg IE
Ann Rheum Dis 82 (-) 574 [2023-06-00; online 2023-06-00]
OxLDL sensitizes platelets for increased formation of extracellular vesicles capable of finetuning macrophage gene expression.
Maaninka K, Neuvonen M, Kerkelä E, ..., Öörni K, Siljander PR
Eur J Cell Biol 102 (2) 151311 [2023-06-00; online 2023-03-15]
OP0021 STRATIFICATION OF PATIENTS WITH SJÖGREN'S SYNDROME BY JOINT MULTI-MODAL ANALYSIS OF CIRCULATING B CELLS
Arvidsson G, Czarnewski P, Johansson A, ..., Nordmark G, Syvänen AC
Ann Rheum Dis 82 (-) 13-14 [2023-06-00; online 2023-06-00]
Mobility and the spatial spread of sars-cov-2 in Belgium.
Rollier M, Miranda GHB, Vergeynst J, ..., Belgian Collaborative Group on covid-19 Hospital Surveillance , Baetens JM
Math Biosci 360 (-) 108957 [2023-06-00; online 2023-02-17]
Gisele Miranda SciLifeLab Fellow
In situ architecture of the ER-mitochondria encounter structure.
Wozny MR, Di Luca A, Morado DR, ..., Vanni S, Kukulski W
Nature 618 (7963) 188-192 [2023-06-00; online 2023-05-10]
Diagnostic Yield From a Nationwide Implementation of Precision Medicine for all Children With Cancer.
Wadensten E, Wessman S, Abel F, ..., Gisselsson D, Genomic Medicine Sweden Childhood Cancer Working Group
JCO Precis Oncol 7 (-) e2300039 [2023-06-00; online 2023-06-29]
Comparison of two supporting matrices for patient-derived cancer cells in 3D drug sensitivity and resistance testing assay (3D-DSRT).
Feodoroff M, Mikkonen P, Turunen L, ..., Kallioniemi O, Pietiäinen V
SLAS Discov 28 (4) 138-148 [2023-06-00; online 2023-03-20]
Author Correction: Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer.
Akdemir KC, Le VT, Chandran S, ..., PCAWG Structural Variation Working Group , PCAWG Consortium
Nat. Genet. 55 (6) 1079 [2023-06-00; online 2023-03-23]
AIRR community curation and standardised representation for immunoglobulin and T cell receptor germline sets.
Lees WD, Christley S, Peres A, ..., Busse CE, AIRR Community
ImmunoInformatics 10 (-) - [2023-06-00; online 2023-02-19]
Triazole fungicides induce adipogenesis and repress osteoblastogenesis in zebrafish.
Thrikawala S, Mesmar F, Bhattacharya B, ..., Williams C, Bondesson M
Toxicol Sci 193 (2) 119-130 [2023-05-31; online 2023-03-24]
The impact of TLR2 and aging on the humoral immune response to Staphylococcus aureus bacteremia in mice.
Gupta P, Hu Z, Kopparapu PK, ..., Jin T, Engdahl C
Sci Rep 13 (1) 8850 [2023-05-31; online 2023-05-31]
Spatially resolved multiomics on the neuronal effects induced by spaceflight
Masarapu Y, Cekanaviciute E, Andrusivova Z, ..., Costes S, Giacomello S
- - (-) - [2023-05-31; online 2023-05-31]
Discovery of non-reference processed pseudogenes in the Swedish population.
Ten Berk de Boer E, Bilgrav Saether K, Eisfeldt J
Front Genet 14 (-) 1176626 [2023-05-30; online 2023-05-30]
Helicobacter pylori attachment-blocking antibodies protect against duodenal ulcer disease.
Bugaytsova JA, Moonens K, Piddubnyi A, ..., Hammarström L, Borén T
bioRxiv - (-) - [2023-05-24; online 2023-05-24]
Targeting NETs using dual-active DNase1 variants.
Englert H, Göbel J, Khong D, ..., Fuchs TA, Renné T
Front Immunol 14 (-) 1181761 [2023-05-23; online 2023-05-23]
Sequence enrichment profiles enable target-agnostic antibody generation for a broad range of antigens.
Mattsson J, Ljungars A, Carlsson A, ..., Ohlin M, Frendéus B
Cell Rep Methods 3 (5) 100475 [2023-05-22; online 2023-05-09]
RNA interactome capture in Escherichia coli globally identifies RNA-binding proteins.
Stenum TS, Kumar AD, Sandbaumhüter FA, ..., Jansson ET, Holmqvist E
Nucleic Acids Res. 51 (9) 4572-4587 [2023-05-22; online 2023-03-30]
Membranes in focus.
Sezgin E, Levental I
Biophys. J. - (-) - [2023-05-19; online 2023-05-19]
Erdinc Sezgin SciLifeLab Fellow
The single-cell transcriptional landscape of innate and adaptive lymphocytes in pediatric-onset colitis.
Kokkinou E, Soini T, Pandey RV, ..., Rolandsdotter H, Mjösberg J
Cell Rep Med 4 (5) 101038 [2023-05-16; online 2023-05-08]
Chromatin insulation orchestrates matrix metalloproteinase gene cluster expression reprogramming in aggressive breast cancer tumors
Llinàs-Arias P, Orozco JI, Ensenyat-Mendez M, ..., Lupien M, Marzese D
- - (-) - [2023-05-11; online 2023-05-11]
The Broad Spectrum of TP53 Mutations in CLL: Evidence of Multiclonality and Novel Mutation Hotspots.
Lazarian G, Leroy B, Theves F, ..., Soussi T, French Innovative Leukemia Organization (FILO)
Hum. Mutat. 2023 (-) 4880113 [2023-05-09; online 2023-05-09]
Plasma protein changes reflect colorectal cancer development and associated inflammation.
Urbiola-Salvador V, Jabłońska A, Miroszewska D, ..., Li B, Chen Z
Front Oncol 13 (-) 1158261 [2023-05-09; online 2023-05-09]
Ball-and-Chain Inactivation in Potassium Channels.
Sukomon N, Fan C, Nimigean CM
Annu Rev Biophys 52 (-) 91-111 [2023-05-09; online 2023-01-10]
Genomics of adaptive evolution in the woolly mammoth.
Díez-Del-Molino D, Dehasque M, Chacón-Duque JC, ..., van der Valk T, Dalén L
Curr. Biol. 33 (9) 1753-1764.e4 [2023-05-08; online 2023-04-07]
DDLS Fellow Tom van der Valk
SAG-RAD: A Method for Single-Cell Population Genomics of Unicellular Eukaryotes.
Gollnisch R, Wallenius J, Gribble KE, Ahrén D, Rengefors K
Mol. Biol. Evol. 40 (5) - [2023-05-02; online 2023-04-20]
Micro Germline-Restricted Chromosome in Blue Tits: Evidence for Meiotic Functions.
Mueller JC, Schlebusch SA, Pei Y, ..., Suh A, Kempenaers B
Mol. Biol. Evol. 40 (5) - [2023-05-02; online 2023-04-28]
Lab-in-a-fiber-based integrated particle separation and counting.
Kumar T, Harish AV, Etcheverry S, ..., Laurell F, Russom A
Lab Chip 23 (9) 2286-2293 [2023-05-02; online 2023-05-02]
Chiropterans Are a Hotspot for Horizontal Transfer of DNA Transposons in Mammalia.
Paulat NS, Storer JM, Moreno-Santillán DD, ..., Karlsson EK, Ray DA
Mol. Biol. Evol. 40 (5) - [2023-05-02; online 2023-04-18]
Modelling Brain in a Chip.
Ashammakhi N, Nasiri R, Contag CH, Herland A
J Craniofac Surg 34 (3) 845-847 [2023-05-01; online 2023-03-24]
Anti-IL-6R prevents experimental type 1 diabetes
Luo Z, Hamze N, Berggren E, ..., Sandler S, Singh K
J. Immunol. 210 (Supplement_1) 165.20-165.20 [2023-05-01; online 2023-05-01]
Daniel Espes SciLifeLab Fellow
TissUUmaps 3: Improvements in interactive visualization, exploration, and quality assessment of large-scale spatial omics data.
Pielawski N, Andersson A, Avenel C, ..., Solorzano L, Wählby C
Heliyon 9 (5) e15306 [2023-05-00; online 2023-04-17]
The association between genetically elevated polyunsaturated fatty acids and risk of cancer.
Haycock PC, Borges MC, Burrows K, ..., Martin RM, Fatty Acids in Cancer Mendelian Randomization Collaboration
EBioMedicine 91 (-) 104510 [2023-05-00; online 2023-04-20]
Prediction of risk for myeloid malignancy in clonal hematopoiesis.
Weeks LD, Niroula A, Neuberg D, ..., Natarajan P, Ebert BL
NEJM Evid 2 (5) - [2023-05-00; online 2023-04-25]
Abhishek Niroula DDLS Fellow
Plasma lipidome and risk of atrial fibrillation: results from the PREDIMED trial.
Toledo E, Wittenbecher C, Razquin C, ..., Hu FB, Martínez-González MA
J Physiol Biochem 79 (2) 355-364 [2023-05-00; online 2023-04-01]
Clemens Wittenbecher DDLS Fellow
Naturally occurring dipeptide from elite controllers with dual anti-HIV-1 mechanism.
Ceña-Diez R, Narayanan A, Ray S, ..., van Domselaar R, Sönnerborg A
Int. J. Antimicrob. Agents 61 (5) 106792 [2023-05-00; online 2023-03-15]
Itch receptor MRGPRX4 interacts with the receptor activity-modifying proteins.
Kotliar IB, Ceraudo E, Kemelmakher-Liben K, ..., Schwenk JM, Sakmar TP
J Biol Chem 299 (5) 104664 [2023-05-00; online 2023-03-30]
Insulin thermostability in a real-world setting.
Pendsey S, James S, Garrett TJ, ..., Forsander G, Ogle GD
The Lancet Diabetes & Endocrinology 11 (5) 310-312 [2023-05-00; online 2023-03-29]
Hepatic Innervations and Nonalcoholic Fatty Liver Disease.
Adori M, Bhat S, Gramignoli R, ..., Uhlèn M, Adori C
Semin Liver Dis 43 (2) 149-162 [2023-05-00; online 2023-05-08]
Cotranslational folding of human growth hormone in vitro and in Escherichia coli.
Mermans D, Nicolaus F, Baygin A, von Heijne G
FEBS Lett. 597 (10) 1355-1362 [2023-05-00; online 2022-12-22]
Conditionally activated affibody-based prodrug targeting EGFR demonstrates improved tumour selectivity.
Dahlsson Leitao C, Mestre Borras A, Xu T, ..., Vorobyeva A, Löfblom J
J Control Release 357 (-) 185-195 [2023-05-00; online 2023-03-31]
1585 RET proto-oncogene drives cutaneous squamous carcinoma by inhibiting keratinocyte differentiation
Srivastava A, Tommasi C, Sessions D, ..., Lopez-Pajares V, Lee CS
J. Invest. Dermatol. 143 (5) S272 [2023-05-00; online 2023-05-00]
Protein Structural Analysis by Cryogenic Electron Microscopy.
Hall M, Schexnaydre E, Holmlund C, Carroni M
Methods in molecular biology (Clifton, N.J.) 2652 (-) 439-463 [2023-04-24; online 2023-04-24]
Genomic, transcriptomic and epigenomic sequencing data of the B- cell leukemia cell line REH
Wiklander ML, Övernäs E, Lagensjö J, ..., Liljedahl U, Nordlund J
- - (-) - [2023-04-24; online 2023-04-24]
Size matters: the impact of nucleus size on results from spatial transcriptomics.
Mohammadi E, Chojnowska K, Bieńkowski M, ..., Piotrowski A, Mieczkowski J
J Transl Med 21 (1) 270 [2023-04-21; online 2023-04-21]
Comparison of SARS-CoV-2 whole genome sequencing using tiled amplicon enrichment and bait hybridization.
Koskela von Sydow A, Lindqvist CM, Asghar N, ..., Mölling P, Stenmark B
Sci Rep 13 (1) 6461 [2023-04-20; online 2023-04-20]
Development of top-down cortical propagations in youth.
Pines A, Keller AS, Larsen B, ..., Fair DA, Satterthwaite TD
Neuron 111 (8) 1316-1330.e5 [2023-04-19; online 2023-02-17]
DDLS Fellow Jacob W Vogel
ERβ in Granulosa Cell Tumors and Its Clinical Potential.
Birgersson M, Indukuri R, Antonson P, ..., Archer A, Williams C
Endocrinology 164 (6) - [2023-04-17; online 2023-04-19]
Y-linked copy number polymorphism of target of rapamycin (TOR) is associated with sexual size dimorphism in seed beetles
Kaufmann P, Wiberg RAW, Papachristos K, ..., Tellgren-Roth C, Immonen E
- - (-) - [2023-04-15; online 2023-04-15]
Abstract LB362: Epigenome-wide DNA methylation alterations precede diagnosis since birth and affect prognosis of pediatric B-cell acute lymphoblastic leukemia
Ghantous A, Nusslé SG, Nassar F, ..., Munthe-Kaas MC, Herceg Z
Cancer Res. 83 (8_Supplement) LB362-LB362 [2023-04-14; online 2023-04-14]
M-Ionic: Prediction of metal ion binding sites from sequence using residue embeddings
Shenoy A, Kalakoti Y, Sundar D, Elofsson A
- - (-) - [2023-04-06; online 2023-04-06]
Operator dashboard for controlling the NeIC Sensitive Data Archive
Viklund J, Negru S, Bahena S, ..., Keskin BE, Shivakumara S
- - (-) - [2023-04-05; online 2023-04-05]
Onboarding suite for Federated EGA nodes
Negru S, Viklund J, Bampalikis D
- - (-) - [2023-04-05; online 2023-04-05]
Abstract 3778: Genome-Scale CRISPRa and CRISPRi screening for lncRNA drivers of prostate cancer progression
Weiss S, Lord A, Schmierer B, ..., Borre M, Sørensen KD
Cancer Res. 83 (7_Supplement) 3778-3778 [2023-04-04; online 2023-04-04]
Abstract 1793: Single-cell RNA analysis reveal effector-like CD8+ CAR-T cell subpopulations associated with response in lymphoma patients
Sarén T, Ramachandran M, Gammelgård G, ..., Enblad G, Essand M
Cancer Res. 83 (7_Supplement) 1793-1793 [2023-04-04; online 2023-04-04]
Prospective changes in insulin response and cellularity of white adipose tissue following long-term weight loss
Massier L, Bäckdahl J, Jalkanen J, ..., Rydén M, Mejhert N
Diabetologie und Stoffwechsel 18 (S 01) S2-S2 [2023-04-00; online 2023-05-02]
Optimizing insect metabarcoding using replicated mock communities.
Iwaszkiewicz-Eggebrecht E, Granqvist E, Buczek M, ..., Ronquist F, Łukasik P
Methods Ecol Evol 14 (4) 1130-1146 [2023-04-00; online 2023-02-13]
Novel therapeutic approaches for pleural mesothelioma identified by functional ex vivo drug sensitivity testing.
Ollila-Raj H, Murumägi A, Pellinen T, ..., Mäyränpää MI, Ilonen I
Lung Cancer 178 (-) 213-219 [2023-04-00; online 2023-03-01]
Heterologous inactivated virus/mRNA vaccination response to BF.7, BQ.1.1, and XBB.1.
Zuo F, Sun R, Abolhassani H, ..., Marcotte H, Pan-Hammarström Q
Lancet Reg Health West Pac 33 (-) 100762 [2023-04-00; online 2023-04-12]
CD93 maintains endothelial barrier function by limiting the phosphorylation and turnover of VE-cadherin.
Lugano R, Vemuri K, Barbera S, ..., Claesson-Welsh L, Dimberg A
FASEB J. 37 (4) e22894 [2023-04-00; online 2023-03-25]
Author Correction: Butler enables rapid cloud-based analysis of thousands of human genomes.
Yakneen S, Waszak SM, PCAWG Technical Working Group , ..., Korbel JO, PCAWG Consortium
Nat. Biotechnol. 41 (4) 577 [2023-04-00; online 2023-03-23]
Data from Patterns of Human Leukocyte Antigen Class I and Class II Associations and Cancer
Liu Z, Derkach A, Yu KJ, ..., Hildesheim A, Pfeiffer RM
- - (-) - [2023-03-31; online 2023-03-31]
Data from Molecular Characteristics of ERCC1-Negative versus ERCC1-Positive Tumors in Resected NSCLC
Friboulet L, Barrios-Gonzales D, Commo F, ..., André F, Soria JC
- - (-) - [2023-03-31; online 2023-03-31]
Data from <i>SETD2</i> Is Recurrently Mutated in Whole-Exome Sequenced Canine Osteosarcoma
Sakthikumar S, Elvers I, Kim J, ..., Marinescu VD, Lindblad-Toh K
- - (-) - [2023-03-31; online 2023-03-31]
Data from <i>SETD2</i> Is Recurrently Mutated in Whole-Exome Sequenced Canine Osteosarcoma
Sakthikumar S, Elvers I, Kim J, ..., Marinescu VD, Lindblad-Toh K
- - (-) - [2023-03-31; online 2023-03-31]
Data from 6-Thioguanine Selectively Kills BRCA2-Defective Tumors and Overcomes PARP Inhibitor Resistance
Issaeva N, Thomas HD, Djurenovic T, ..., Curtin NJ, Helleday T
- - (-) - [2023-03-30; online 2023-03-30]
Analysis of human lung mast cells by single cell RNA sequencing.
Rönnberg E, Ravindran A, Mazzurana L, ..., Mjösberg J, Nilsson G
Front Immunol 14 (-) 1151754 [2023-03-30; online 2023-03-30]
A small noncoding RNA links ribosome recovery and translation control to dedifferentiation during salamander limb regeneration.
Subramanian E, Elewa A, Brito G, ..., Andersson O, Simon A
Dev. Cell 58 (6) 450-460.e6 [2023-03-27; online 2023-03-08]
Prediction model for drug response of acute myeloid leukemia patients.
Trac QT, Pawitan Y, Mou T, ..., Kallioniemi O, Vu TN
NPJ Precis Oncol 7 (1) 32 [2023-03-24; online 2023-03-24]
Micro-scale spatial preference and temporal cyclicity linked to foraging in harbour porpoises
Stedt J, Wahlberg M, Carlström J, ..., Oskolkov N, Carlsson P
Mar. Ecol. Prog. Ser. 708 (-) 143-161 [2023-03-23; online 2023-03-23]
Chiropterans are a hotspot for horizontal transfer of DNA transposons in Mammalia
Paulat NS, Storer JM, Moreno-Santillán DD, ..., Karlsson EK, Ray DA
- - (-) - [2023-03-23; online 2023-03-23]
PD-L1ATTAC mice reveal the potential of depleting PD-L1 expressing cells in cancer therapy.
Fueyo-Marcos E, Lopez-Pernas G, Fustero-Torre C, ..., Fernández-Capetillo O, Murga M
Aging (Albany NY) 15 (6) 1791-1807 [2023-03-22; online 2023-03-22]
Targeting Glioblastoma-Associated Macrophages for Photodynamic Therapy Using AGuIX®-Design Nanoparticles.
Lerouge L, Gries M, Chateau A, ..., Thomas N, Barberi-Heyob M
Pharmaceutics 15 (3) - [2023-03-20; online 2023-03-20]
Amino acid usage and tRNA expression underlies proteome adaptation in Plasmodium falciparum
Li Q, Vetter L, Veith Y, ..., Larsson O, Chan SCL
- - (-) - [2023-03-20; online 2023-03-20]
Structural Elucidation of Ivermectin Binding to α7nAChR and the Induced Channel Desensitization.
Bondarenko V, Chen Q, Singewald K, ..., Xu Y, Tang P
ACS Chem Neurosci 14 (6) 1156-1165 [2023-03-15; online 2023-02-23]
A positive feedback loop driven by fibronectin and IL-1β sustains the inflammatory microenvironment in breast cancer.
Tunali G, Yanik H, Ozturk SC, ..., Van Obberghen-Schilling E, Esendagli G
Breast Cancer Res. 25 (1) 27 [2023-03-15; online 2023-03-15]
Heparanase Modulates Chromatin Accessibility.
Li H, Zhang H, Wenz A, ..., Chen X, Li J
Cells 12 (6) - [2023-03-14; online 2023-03-14]
The Drug Repurposing Encyclopedia (DRE): a web server for systematic drug repurposing across 20 organisms
Li X, Pan L, Sanchez-Burgos L, Hühn D, Fernandez-Capetillo O
- - (-) - [2023-03-12; online 2023-03-12]
Leveraging Base Pair Mammalian Constraint to Understand Genetic Variation and Human Disease.
Sullivan PF, Meadows JRS, Gazal S, ..., Karlsson EK, Lindblad-Toh K
bioRxiv - (-) - [2023-03-10; online 2023-03-10]
Inference and reconstruction of the heimdallarchaeial ancestry of eukaryotes
Eme L, Tamarit D, Caceres EF, ..., Baker BJ, Ettema TJG
- - (-) - [2023-03-09; online 2023-03-09]
Evolutionary constraint and innovation across hundreds of placental mammals
Christmas MJ, Kaplow IM, Genereux DP, ..., Lindblad-Toh K, Karlsson EK
- - (-) - [2023-03-09; online 2023-03-09]
Latent antibiotic resistance genes are abundant, diverse, and mobile in human, animal, and environmental microbiomes.
Inda-Díaz JS, Lund D, Parras-Moltó M, ..., Bengtsson-Palme J, Kristiansson E
Microbiome 11 (1) 44 [2023-03-08; online 2023-03-08]
DDLS Fellow
Short term starvation potentiates the efficacy of chemotherapy in triple negative breast cancer via metabolic reprogramming.
Pateras IS, Williams C, Gianniou DD, ..., Gilthorpe JD, Frisan T
J Transl Med 21 (1) 169 [2023-03-03; online 2023-03-03]
Targeting the nucleolus as a therapeutic strategy in human disease.
Corman A, Sirozh O, Lafarga V, Fernandez-Capetillo O
Trends Biochem. Sci. 48 (3) 274-287 [2023-03-00; online 2022-10-10]
Rapid adaptations of Legionella pneumophila to the human host.
Leenheer D, Moreno AB, Paranjape K, ..., Ginevra C, Guy L
Microb Genom 9 (3) - [2023-03-00; online 2023-03-23]
Protocol for 3D drug sensitivity and resistance testing of patient-derived cancer cells in 384-well plates.
Feodoroff M, Mikkonen P, Arjama M, ..., Turunen L, Pietiäinen V
SLAS Discov 28 (2) 36-41 [2023-03-00; online 2022-12-01]
Palidis: fast discovery of novel insertion sequences.
Carr VR, Pissis SP, Mullany P, ..., Gomez-Cabrero D, Moyes DL
Microb Genom 9 (3) - [2023-03-00; online 2023-03-11]
Saeed Shoaie SciLifeLab Fellow
Exosomes: A missing link between chronic systemic inflammation and Alzheimer's disease?
Ozansoy M, Mikati H, Velioglu HA, Yulug B
Biomed. Pharmacother. 159 (-) 114161 [2023-03-00; online 2023-01-13]
Comparison of HER2-targeted affibody conjugates loaded with auristatin- and maytansine-derived drugs.
Yin W, Xu T, Ding H, ..., Gräslund T, Vorobyeva A
J Control Release 355 (-) 515-527 [2023-03-00; online 2023-02-14]
African Farmers, Not Stone Age Foragers: Reassessment of Human Remains from the Mumbwa Caves, Zambia
Steyn M, Meyer A, Peyroteo-Stjerna R, ..., Barham L, Lombard M
Afr Archaeol Rev 40 (1) 53-72 [2023-03-00; online 2022-12-14]
A Microfluidic Contact Lens to Address Contact Lens-Induced Dry Eye.
Zhu Y, Nasiri R, Davoodi E, ..., Toyserkani E, Khademhosseini A
Small 19 (11) e2207017 [2023-03-00; online 2022-12-23]
Building a precision medicine infrastructure at a national level: The Swedish experience.
Edsjö A, Lindstrand A, Gisselsson D, ..., Rosenquist R, Genomic Medicine Sweden (GMS)
Camb Prism Precis Med 1 (-) e15 [2023-02-27; online 2023-02-27]
A 3D Bioprinted Gut Anaerobic Model for Studying Bacteria-Host Interactions.
Cheng L, Liu T, Liu Q, ..., Zhang YS, Du J
Research (Wash D C) 6 (-) 0058 [2023-02-27; online 2023-02-27]
Targeted plasma proteomics reveals signatures discriminating COVID-19 from sepsis with pneumonia.
Palma Medina LM, Babačić H, Dzidic M, ..., Strålin K, Norrby-Teglund A
Respir. Res. 24 (1) 62 [2023-02-24; online 2023-02-24]
Antisecretory factor is safe to use as add-on treatment in newly diagnosed glioblastoma.
Ehinger E, Kopecky J, Darabi A, ..., Bengzon J, Siesjö P
BMC Neurol 23 (1) 76 [2023-02-18; online 2023-02-18]
Phenotypic screening platform identifies statins as enhancers of immune cell-induced cancer cell death.
Selvin T, Berglund M, Lenhammar L, ..., Larsson R, Andersson CR
BMC Cancer 23 (1) 164 [2023-02-17; online 2023-02-17]
Generation of tumor spheroids in microwells to study NK cell cytotoxicity, infiltration and phenotype.
Carannante V, Sandström N, Olofsson K, ..., Wiklund M, Önfelt B
Methods Cell Biol 178 (-) 195-208 [2023-02-16; online 2023-02-16]
A critical role of VEGFR2 in lymphatic tumor metastasis
Li T, Cao X, Zhou F, ..., Makinen T, He Y
- - (-) - [2023-02-16; online 2023-02-16]
Population Genomics for Insect Conservation.
Webster MT, Beaurepaire A, Neumann P, Stolle E
Annu Rev Anim Biosci 11 (-) 115-140 [2023-02-15; online 2022-11-14]
When Two Become One: Conformational Changes in FXR/RXR Heterodimers Bound to Steroidal Antagonists.
Díaz-Holguín A, Rashidian A, Pijnenburg D, ..., Pavek P, Kronenberger T
ChemMedChem 18 (4) e202200556 [2023-02-14; online 2022-11-30]
Genetic mechanisms of 184 neuro-related proteins in human plasma.
Repetto L, Chen J, Yang Z, ..., Navarro P, Shen X
medRxiv - (-) - [2023-02-14; online 2023-02-14]
Array-Based Multiplex and High-Throughput Serology Assays.
Olofsson J, Hellström C, Andersson E, ..., Nilsson P, Pin E
Methods in molecular biology (Clifton, N.J.) 2628 (-) 535-553 [2023-02-14; online 2023-02-14]
Mechanical forces at the kidney filtration barrier govern spatial orientation of podocyte processes on capillaries
Unnersjö-Jess D, Ramdedovic A, Butt L, ..., Schermer B, Benzing T
- - (-) - [2023-02-10; online 2023-02-10]
Loss of Y is associated with multi-omic changes in immune cells from Alzheimer’s disease patients
Jąkalski M, Rychlicka-Buniowska E, Davies H, ..., Dumanski JP, Mieczkowski J
- - (-) - [2023-02-08; online 2023-02-08]
Heterologous inactivated virus/mRNA vaccination response to BF.7, BQ.1.1, and XBB.1
Zuo F, Sun R, Abolhassani H, ..., Marcotte H, Pan-Hammarström Q
- - (-) - [2023-02-07; online 2023-02-07]
The anti-leprosy drug clofazimine reduces polyQ toxicity through activation of PPAR
Li X, Hernandez I, Häggblad M, ..., Hühn D, Fernandez-Capetillo O
- - (-) - [2023-02-06; online 2023-02-06]
scAEGAN: Unification of single-cell genomics data by adversarial learning of latent space correspondences.
Khan SA, Lehmann R, Martinez-de-Morentin X, ..., Gomez-Cabrero D, Tegner J
PLoS ONE 18 (2) e0281315 [2023-02-03; online 2023-02-03]
Loci for insulin processing and secretion provide insight into type 2 diabetes risk.
Broadaway KA, Yin X, Williamson A, ..., Wheeler E, Mohlke KL
Am. J. Hum. Genet. 110 (2) 284-299 [2023-02-02; online 2023-01-23]
Impact of the gut microbiome on immunological responses to COVID-19 vaccination in healthy controls and people living with HIV
Ray S, Narayanan A, Vesterbacka J, ..., Sönnerborg A, Nowak P
- - (-) - [2023-02-02; online 2023-02-02]
Data-driven neuropathological staging and subtyping of TDP-43 proteinopathies.
Young AL, Vogel JW, Robinson JL, ..., Lee EB, Hansson O
medRxiv - (-) - [2023-02-02; online 2023-02-02]
T cell receptor gene repertoire profiles in subgroups of patients with chronic lymphocytic leukemia bearing distinct genomic aberrations.
Vlachonikola E, Pechlivanis N, Karakatsoulis G, ..., Stamatopoulos K, Chatzidimitriou A
Front Oncol 13 (-) 1097942 [2023-02-01; online 2023-02-01]
Long-term SARS-CoV-2 surveillance in the wastewater of Stockholm: What lessons can be learned from the Swedish perspective?
Perez-Zabaleta M, Archer A, Khatami K, ..., Williams C, Cetecioglu Z
Sci. Total Environ. 858 (Pt 3) 160023 [2023-02-01; online 2022-11-08]
Sensing of protein and DNA complexes using solid-state nanopores
Jain S, Birgersson M, Kipen J, ..., Williams C, Herland A
Biophysical Journal 122 (3) 289a [2023-02-00; online 2023-02-00]
Genome sequencing is a sensitive first-line test to diagnose individuals with intellectual disability
Lindstrand A, Ek M, Kvarnung M, ..., Pettersson M, Nordgren A
Pathology 55 (-) S19-S20 [2023-02-00; online 2023-02-00]
Delineating Plasmodium liver infection across space and time.
Hildebrandt F, Ankarklev J, Matuschewski K
Trends Parasitol. 39 (2) 80-82 [2023-02-00; online 2022-12-24]
Author Correction: The repertoire of mutational signatures in human cancer.
Alexandrov LB, Kim J, Haradhvala NJ, ..., Stratton MR, PCAWG Consortium
Nature 614 (7948) E41 [2023-02-00; online 2023-01-26]
Author Correction: The evolutionary history of 2,658 cancers.
Gerstung M, Jolly C, Leshchiner I, ..., Van Loo P, PCAWG Consortium
Nature 614 (7948) E42 [2023-02-00; online 2023-01-26]
Author Correction: Patterns of somatic structural variation in human cancer genomes.
Li Y, Roberts ND, Wala JA, ..., Campbell PJ, PCAWG Consortium
Nature 614 (7948) E38 [2023-02-00; online 2023-01-26]
Author Correction: Pan-cancer analysis of whole genomes.
ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium
Nature 614 (7948) E39 [2023-02-00; online 2023-01-26]
Author Correction: Genomic basis for RNA alterations in cancer.
PCAWG Transcriptome Core Group , Calabrese C, Davidson NR, ..., Zhang Z, PCAWG Consortium
Nature 614 (7948) E37 [2023-02-00; online 2023-01-26]
Author Correction: Analyses of non-coding somatic drivers in 2,658 cancer whole genomes.
Rheinbay E, Nielsen MM, Abascal F, ..., Getz G, PCAWG Consortium
Nature 614 (7948) E40 [2023-02-00; online 2023-01-26]
A Prox1 enhancer represses haematopoiesis in the lymphatic vasculature.
Kazenwadel J, Venugopal P, Oszmiana A, ..., Scott HS, Harvey NL
Nature 614 (7947) 343-348 [2023-02-00; online 2023-01-25]
7-month duration of SARS-CoV-2 mucosal immunoglobulin-A responses and protection.
Marking U, Bladh O, Havervall S, ..., Klingström J, Thålin C
Lancet Infect Dis 23 (2) 150-152 [2023-02-00; online 2023-01-11]
MDC1 maintains active elongation complexes of RNA polymerase II.
Pappas G, Munk SHN, Watanabe K, ..., Galanos P, Bartek J
Cell Reports 42 (1) 111979 [2023-01-31; online 2023-01-12]
Enhanced translation expands the endo-lysosome size and promotes antigen presentation during phagocyte activation
Hipolito VEB, Diaz JA, Tandoc KV, ..., Topisirovic I, Botelho R
- - (-) - [2023-01-31; online 2023-01-31]
Enhanced translation expands the endo-lysosome size and promotes antigen presentation during phagocyte activation
Hipolito VEB, Diaz JA, Tandoc KV, ..., Topisirovic I, Botelho R
- - (-) - [2023-01-31; online 2023-01-31]
Editorial: Effects of hormonal contraceptives on the brain.
Pletzer B, Comasco E, Hidalgo-Lopez E, Lacreuse A, Derntl B
Front Endocrinol (Lausanne) 14 (-) 1129203 [2023-01-31; online 2023-01-31]
Erika Comasco SciLifeLab Fellow
Molecular quantitative trait loci
Aguet F, Alasoo K, Li YI, ..., Montgomery SB, Lappalainen T
Nat Rev Methods Primers 3 (1) - [2023-01-25; online 2023-01-25]
Metabolic stress-induced human beta-cell death is mediated by increased intracellular levels of adenosine.
Ngamjariyawat A, Cen J, Said R, ..., Idevall-Hagren O, Welsh N
Front Endocrinol (Lausanne) 14 (-) 1060675 [2023-01-25; online 2023-01-25]
Distinct COPD subtypes in former smokers revealed by gene network perturbation analysis.
Buschur KL, Riley C, Saferali A, ..., Hersh CP, Benos PV
Respir. Res. 24 (1) 30 [2023-01-25; online 2023-01-25]
n-Type Organic Electrochemical Transistors with High Transconductance and Stability
Wang Y, Zhu G, Zeglio E, ..., Inal S, Yue W
Chem Mater 35 (2) 405-415 [2023-01-24; online 2023-01-09]
The swan genome and transcriptome, it is not all black and white.
Karawita AC, Cheng Y, Chew KY, ..., Burt DW, Short KR
Genome Biol. 24 (1) 13 [2023-01-23; online 2023-01-23]
High cardiomyocyte diversity in human early prenatal heart development.
Sylvén C, Wärdell E, Månsson-Broberg A, ..., Björklund Å, Giacomello S
iScience 26 (1) 105857 [2023-01-20; online 2022-12-21]
Single-cell analysis of myeloid cells in HPV+ tonsillar cancer.
Jimenez DG, Altunbulakli C, Swoboda S, ..., Greiff L, Lindstedt M
Front Immunol 13 (-) 1087843 [2023-01-19; online 2023-01-19]
Proline catabolism is key to facilitating Candida albicans pathogenicity
Silao FGS, Jiang T, Bereczky-Veress B, ..., Peuckert C, Ljungdahl PO
- - (-) - [2023-01-18; online 2023-01-18]
N-terminal proteoforms may engage in different protein complexes
Bogaert A, Fijalkowska D, Staes A, ..., Calderwood MA, Gevaert K
- - (-) - [2023-01-18; online 2023-01-18]
A chemical screen underscores the essential role of STAT1-dependent IFNγ signaling to regulate HLA-I expression in cancer cells.
Barz M, Porebski B, Panshikar P, ..., Hühn D, Fernandez-Capetillo O
MicroPubl Biol 2023 (-) - [2023-01-18; online 2023-01-18]
The role of the 5’ sensing function of ribonuclease E in cyanobacteria
Hoffmann UA, Lichtenberg E, Rogh SN, ..., Hess WR, Wilde A
- - (-) - [2023-01-13; online 2023-01-13]
Translating single-cell genomics into cell types
Tegner JN
Nat Mach Intell 5 (1) 11-12 [2023-01-12; online 2023-01-12]
PIK3CA is recurrently mutated in canine mammary tumors, similarly to in human mammary neoplasia.
Arendt ML, Sakthikumar S, Melin M, ..., Rönnberg H, Lindblad-Toh K
Sci Rep 13 (1) 632 [2023-01-12; online 2023-01-12]
Origin Matters: Using a Local Reference Genome Improves Measures in Population Genomics
Thorburn DMJ, Sagonas K, Binzer-Panchal M, ..., Lenz TL, Eizaguirre C
- - (-) - [2023-01-11; online 2023-01-11]
Global Biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts.
Wang Y, Namba S, Lopera E, ..., Martin AR, Hirbo J
Cell Genom 3 (1) 100241 [2023-01-11; online 2023-01-04]
A human stomach cell type transcriptome atlas
Öling S, Struck E, Thorsen M, ..., Dusart P, Butler L
- - (-) - [2023-01-11; online 2023-01-11]
Systemic and mucosal adaptive immunity to SARS-CoV-2 during the Omicron wave in patients with chronic lymphocytic leukemia
Ingelman-Sundberg H, Blixt L, Wullimann D, ..., Buggert M, Österborg A
- - (-) - [2023-01-10; online 2023-01-10]
Fibroblast subsets in non-small cell lung cancer: Associations with survival, mutations, and immune features.
Pellinen T, Paavolainen L, Martín-Bernabé A, ..., Micke P, Östman A
J. Natl. Cancer Inst. 115 (1) 71-82 [2023-01-10; online 2022-09-10]
A tissue centric atlas of cell type transcriptome enrichment signatures
Dusart P, Öling S, Struck E, ..., Uhlén M, Butler L
- - (-) - [2023-01-10; online 2023-01-10]
Endogenous incretin levels and risk of first incident cancer: a prospective cohort study.
Jujić A, Godina C, Belting M, ..., Jernström H, Magnusson M
Sci Rep 13 (1) 382 [2023-01-07; online 2023-01-07]
Optimization of N-Piperidinyl-Benzimidazolone Derivatives as Potent and Selective Inhibitors of 8-Oxo-Guanine DNA Glycosylase 1.
Wallner O, Cázares-Körner A, Scaletti ER, ..., Helleday T, Michel M
ChemMedChem 18 (1) e202200310 [2023-01-03; online 2022-10-13]
Fibroblast Growth Factor-23 and Risk of Cardiovascular Diseases: A Mendelian Randomization Study.
Donovan K, Herrington WG, Paré G, ..., Staplin N, on behalf of the SCALLOP Consortium
Clin J Am Soc Nephrol 18 (1) 17-27 [2023-01-01; online 2023-02-01]
Dimerization of the C-type lectin-like receptor CD93 promotes its binding to Multimerin-2 in endothelial cells.
Barbera S, Raucci L, Tassone G, ..., Pozzi C, Orlandini M
Int J Biol Macromol 224 (-) 453-464 [2023-01-01; online 2022-10-18]
Unravelling the landscape of skin cancer through single-cell transcriptomics.
Srivastava A, Bencomo T, Das I, Lee CS
Transl Oncol 27 (-) 101557 [2023-01-00; online 2022-10-17]
Temporally and spatially regulated collagen XVIII isoforms are involved in ureteric tree development via the TSP1-like domain.
Rinta-Jaskari MM, Naillat F, Ruotsalainen HJ, ..., Vainio SJ, Pihlajaniemi TA
Matrix Biol. 115 (-) 139-159 [2023-01-00; online 2023-01-06]
PatchDropout: Economizing Vision Transformers Using Patch Dropout
Liu Y, Matsoukas C, Strand F, Azizpour H, Smith K
- - (-) 3942-3951 [2023-01-00; online 2023-01-00]
NMR spectrum reconstruction as a pattern recognition problem.
Jahangiri A, Han X, Lesovoy D, ..., Achour A, Orekhov V
J Magn Reson 346 (-) 107342 [2023-01-00; online 2022-11-24]
Isothermal Amplification Methods for Point-of-Care Diagnostics of Infectious Diseases
Neumann F, Madaboosi N, Nilsson M
- - (-) 239-286 [2023-01-00; online 2022-11-21]
Bioorthogonal azido-S1P works as substrate for S1PR1.
Sternstein C, Schlegel J, Sauer M, Seibel J
J. Lipid Res. 64 (1) 100311 [2023-01-00; online 2022-11-10]
Bayesian mixed model analysis uncovered 21 risk loci for chronic kidney disease in boxer dogs.
Lingaas F, Tengvall K, Jansen JH, ..., Lindblad-Toh K, Wang C
PLoS Genet 19 (1) e1010599 [2023-01-00; online 2023-01-24]
Autoantigenic properties of the aminoacyl tRNA synthetase family in idiopathic inflammatory myopathies.
Preger C, Notarnicola A, Hellström C, ..., Gräslund S, Jakobsson PJ
J. Autoimmun. 134 (-) 102951 [2023-01-00; online 2022-12-02]
The Role of Willpower in Major Depressive Disorder: An fMRI Study
Yulug B, Uygur B, Sayman D, ..., Velioglu HA, Mardinoglu A
- - (-) - [2023-00-00; online 2023-00-00]
Adil Mardinoglu SciLifeLab Fellow
The MHC-E Peptide Ligand of Checkpoint NKG2A Is Governed by Inflammatory Signals and High Turnover
Middelburg J, Ghaffari S, Schoufour TAW, ..., Weidanz J, van Hall T
- - (-) - [2023-00-00; online 2023-00-00]
Distinct HLA Associations with Autoantibody-Defined Subgroups in Idiopathic Inflammatory Myopathies
Leclair V, Galindo-Feria AS, Rothwell S, ..., Lundberg IE, Diaz-Gallo LM
- - (-) - [2023-00-00; online 2023-00-00]
Cell Segmentation of in situ Transcriptomics Data Using Signed Graph Partitioning
Andersson A, Behanova A, Wählby C, Malmberg F
- - (-) 139-148 [2023-00-00; online 2023-08-24]
Basic Concepts and Emergent Disease Mechanisms of Amyotrophic Lateral Sclerosis
Sirozh O, Saez-Mas A, Lafarga V, Fernandez-Capetillo O
- - (-) 644-665 [2023-00-00; online 2023-00-00]

Publications 9.5.1