Publications 2023

918 publications

Small vessel disease in primary familial brain calcification with novel truncating PDGFB variants.
Yektay Farahmand M, Wasselius J, Englund E, ..., Puschmann A, Ilinca A
Neurol Neurochir Pol 58 (1) 94-105 [2023-12-29; online 2023-12-29]
Mitotic MTH1 inhibitor TH1579 induces PD-L1 expression and inflammatory response through the cGAS-STING pathway
Helleday T, Shen J, Mancina E, ..., Berglund U, Sanjiv K
- - (-) - [2023-12-28; online 2023-12-28]
Mapping of the gene network that regulates glycan clock of ageing.
Frkatović-Hodžić A, Mijakovac A, Miškec K, ..., Zoldoš V, Lauc G
Aging (Albany NY) 15 (24) 14509-14552 [2023-12-26; online 2023-12-26]
Clemens Wittenbecher DDLS Fellow
Translational mapping of spatially resolved transcriptomes in human and mouse pulmonary fibrosis
Franzén L, Lindvall MO, Hühn M, ..., Ståhl PL, Hornberg JJ
- - (-) - [2023-12-21; online 2023-12-21]
A machine learning and live-cell imaging tool kit uncovers small molecules induced phospholipidosis.
Hu H, Tjaden A, Knapp S, Antolin AA, Müller S
Cell Chem Biol 30 (12) 1634-1651.e6 [2023-12-21; online 2023-10-04]
Evaluation of noninvasive biospecimens for transcriptome studies.
Martorella M, Kasela S, Garcia-Flores R, ..., Castel SE, Lappalainen T
BMC Genomics 24 (1) 790 [2023-12-19; online 2023-12-19]
Spatial, temporal and numerical regulation of polar flagella assembly in Pseudomonas putida
Pulido-Sánchez M, Leal-Morales A, López-Sánchez A, Cava F, Govantes F
- - (-) - [2023-12-15; online 2023-12-15]
Preclinical evaluation of Affibody molecule for PET imaging of human pancreatic islets derived from stem cells.
Cheung P, Thorngren J, Zhang B, ..., Lau J, Eriksson O
EJNMMI Res 13 (1) 107 [2023-12-15; online 2023-12-15]
The complex nature of lncRNA-mediated chromatin dynamics in multiple myeloma.
Nylund P, Garrido-Zabala B, Kalushkova A, Wiklund HJ
Front Oncol 13 (-) 1303677 [2023-12-11; online 2023-12-11]
snPATHO-seq: unlocking the pathology archives
Wang T, Harvey K, Morlanes JE, ..., Swarbrick A, Martelotto L
- - (-) - [2023-12-08; online 2023-12-08]
Novel data-driven subtypes and stages of brain atrophy in the ALS-FTD spectrum.
Shen T, Vogel JW, Duda J, ..., Irwin DJ, McMillan CT
Transl Neurodegener 12 (1) 57 [2023-12-07; online 2023-12-07]
Increasing diversity of functional genetics studies to advance biological discovery and human health.
George SHL, Medina-Rivera A, Idaghdour Y, Lappalainen T, Gallego Romero I
Am. J. Hum. Genet. 110 (12) 1996-2002 [2023-12-07; online 2023-11-22]
Experimental design of blending samples to increase precision of 1H NMR urine metabolomics
Bay Nord A, Lindqvist H, Rådjursöga M, ..., Karlsson G, Malmodin D
- - (-) - [2023-12-07; online 2023-12-07]
Experimental design of blending samples to increase precision of 1H NMR urine metabolomics
Bay Nord A, Lindqvist H, Rådjursöga M, ..., Karlsson G, Malmodin D
- - (-) - [2023-12-06; online 2023-12-06]
Experimental design of blending samples to increase precision of 1H NMR urine metabolomics
Bay Nord A, Lindqvist H, Rådjursöga M, ..., Karlsson G, Malmodin D
- - (-) - [2023-12-06; online 2023-12-06]
A surfactant lipid layer of endosomal membranes facilitates airway gas filling in Drosophila.
Tsarouhas V, Liu D, Tsikala G, ..., Strigini M, Samakovlis C
Curr. Biol. 33 (23) 5132-5146.e5 [2023-12-04; online 2023-11-21]
RNA Pol II Assembly Affects ncRNA Expression
Garrido-Godino AI, Gupta I, Pelechano V, Navarro F
- - (-) - [2023-12-01; online 2023-12-01]
Inputs, amplification and sinks of perfluoroalkyl substances at coastal Antarctica.
Casas G, Iriarte J, D'Agostino LA, ..., Jiménez B, Dachs J
Environ Pollut 338 (-) 122608 [2023-12-01; online 2023-09-22]
Infectivity of exhaled SARS-CoV-2 aerosols is sufficient to transmit covid-19 within minutes.
Alsved M, Nyström K, Thuresson S, ..., Medstrand P, Löndahl J
Sci Rep 13 (1) 21245 [2023-12-01; online 2023-12-01]
Utilizing CD44v6 and V600EBRAF-mutation for in vitro targeted combination therapy of thyroid carcinomas.
Mortensen ACL, Imgenberg-Kreuz J, Spiegelberg D, Botling J, Nestor M
Heliyon 9 (12) e22594 [2023-12-00; online 2023-11-20]
Songbird germline-restricted chromosome as a potential arena of genetic conflicts.
Vontzou N, Pei Y, Mueller JC, ..., Schlebusch SA, Suh A
Curr. Opin. Genet. Dev. 83 (-) 102113 [2023-12-00; online 2023-09-19]
Proteomics Analysis Identifying New Markers Related to Alzheimer’s Disease Pathology In Vivo
Binette AP, Salvadó G, Spotorno N, ..., Janelidze S, Hansson O
Alzheimers Dement 19 (S14) - [2023-12-00; online 2023-12-25]
Novel CSF tau biomarkers can be used for disease staging of sporadic Alzheimer’s
Salvadó G, Horie K, Barthélemy NR, ..., Bateman RJ, Hansson O
Alzheimers Dement 19 (S14) - [2023-12-00; online 2023-12-25]
NAD+ regulates nucleotide metabolism and genomic DNA replication.
Munk SHN, Merchut-Maya JM, Adelantado Rubio A, ..., Bartek J, Maya-Mendoza A
Nat. Cell Biol. 25 (12) 1774-1786 [2023-12-00; online 2023-11-13]
High-throughput cell spheroid production and assembly analysis by microfluidics and deep learning.
Trossbach M, Åkerlund E, Langer K, Seashore-Ludlow B, Joensson HN
SLAS Technol 28 (6) 423-432 [2023-12-00; online 2023-03-28]
Growth or death? Control of cell destiny by mTOR and autophagy pathways.
Khalil MI, Ali MM, Holail J, Houssein M
Prog. Biophys. Mol. Biol. 185 (-) 39-55 [2023-12-00; online 2023-11-08]
Engineered organoids for biomedical applications.
Roberto de Barros N, Wang C, Maity S, ..., Kim HJ, Khademhosseini A
Adv. Drug Deliv. Rev. 203 (-) 115142 [2023-12-00; online 2023-11-13]
Both C57BL/KsJ (H2d haplotype) and CB10-H2 (H2b haplotype) mice are highly susceptible to congenital toxoplasmosis.
Coutinho LB, de Oliveira MC, Araujo ECB, ..., Czarnewski P, Silva NM
Acta Trop 248 (-) 107022 [2023-12-00; online 2023-09-15]
Advances in genome-scale metabolic models of industrially important fungi.
Han Y, Tafur Rangel A, Pomraning KR, Kerkhoven EJ, Kim J
Curr. Opin. Biotechnol. 84 (-) 103005 [2023-12-00; online 2023-10-03]
A STRP-ed definition of Structured Tandem Repeats in Proteins.
Monzon AM, Arrías PN, Elofsson A, ..., Kajava AV, Tosatto SCE
J. Struct. Biol. 215 (4) 108023 [2023-12-00; online 2023-08-29]
Improved production of Taxol® precursors in S. cerevisiae using combinatorial in silico design and metabolic engineering.
Malcı K, Santibáñez R, Jonguitud-Borrego N, ..., Kerkhoven EJ, Rios-Solis L
Microb Cell Fact 22 (1) 243 [2023-11-29; online 2023-11-29]
Exploring Gut Microbiota Metabolism—New Chemical Biology Tools for Metabolomics Analysis
Dovhalyuk V, Kaur A, Lin W, ..., Mwasambu S, Globisch D
- - (-) 64 [2023-11-29; online 2023-11-29]
Chromatin insulation orchestrates matrix metalloproteinase gene cluster expression reprogramming in aggressive breast cancer tumors.
Llinàs-Arias P, Ensenyat-Mendez M, Íñiguez-Muñoz S, ..., Lupien M, Marzese DM
Mol Cancer 22 (1) 190 [2023-11-28; online 2023-11-28]
Autophagy-mediated control of ribosome homeostasis in oncogene-induced senescence.
López AR, Jørgensen MH, Havelund JF, ..., Happonen L, Frankel LB
Cell Reports 42 (11) 113381 [2023-11-28; online 2023-11-05]
Affibody-based hBCMA x CD16 dual engagers for NK cell-mediated killing of multiple myeloma cells.
Giang KA, Boxaspen T, Diao Y, ..., Malmberg KJ, Nygren PÅ
N Biotechnol 77 (-) 139-148 [2023-11-25; online 2023-09-04]
Mitotic MTH1 Inhibitors in Treatment of Cancer.
Helleday T
Cancer Treat Res 186 (-) 223-237 [2023-11-18; online 2023-11-18]
Pooled optical screening in bacteria using chromosomally expressed barcodes
Soares RRG, García-Soriano DA, Larsson J, ..., Nilsson M, Elf J
- - (-) - [2023-11-17; online 2023-11-17]
Factors driving PPCPs uptake by crops after wastewater irrigation and human health implications.
Sunyer-Caldú A, Quintana G, Diaz-Cruz MS
Environ. Res. 237 (Pt 1) 116923 [2023-11-15; online 2023-08-19]
Associations between the chemical exposome and pregnancy induced hypertension.
Soomro MH, England-Mason G, Liu J, ..., Dewey D, APrON Study Team
Environ. Res. 237 (Pt 1) 116838 [2023-11-15; online 2023-08-05]
Altered plasma protein profiles in genetic FTD - a GENFI study.
Ullgren A, Öijerstedt L, Olofsson J, ..., Graff C, Genetic Frontotemporal Dementia Initiative (GENFI)
Mol Neurodegener 18 (1) 85 [2023-11-15; online 2023-11-15]
High clonal diversity and spatial genetic admixture in early prostate cancer and surrounding normal tissue
Zhang N, Harbers L, Simonetti M, ..., Bienko M, Crosetto N
- - (-) - [2023-11-11; online 2023-11-11]
TMIC-57. CHARTING THE SPATIAL ARCHITECTURE OF GLIOBLASTOMA USING GBMAP: INSIGHTS FROM IN SITU SEQUENCING
Ruiz C, Marco-Salas S, Samuelsson E, ..., Nilsson M, Stunnenberg H
Neuro-oncology 25 (Supplement_5) v291-v291 [2023-11-10; online 2023-11-10]
Core genes driving climate adaptation in plants
Yeaman S, Whiting J, Booker T, ..., Wright S, Zhou L
- - (-) - [2023-11-10; online 2023-11-10]
Pascal Milesi SciLifeLab Fellow
The roles of surround inhibition for the intrinsic function of the striatum, analyzed in silico.
Frost Nylén J, Hjorth JJJ, Kozlov A, ..., Hellgren Kotaleski J, Grillner S
Proc. Natl. Acad. Sci. U.S.A. 120 (45) e2313058120 [2023-11-07; online 2023-11-03]
coRIC map: a framework for the exploration of multifaceted subcellular RNA-binding proteins
Lv Y, Guo X, Hu J, ..., Zhang X, Esteban MA
- - (-) - [2023-11-06; online 2023-11-06]
Enhancers dysfunction in the 3D genome of cancer cells.
Della Chiara G, Jiménez C, Virdi M, Crosetto N, Bienko M
Front Cell Dev Biol 11 (-) 1303862 [2023-11-06; online 2023-11-06]
The Role of Small Nucleolar RNAs As Putative Biomarkers of Chemoresistance in Pediatric Acute Lymphoblastic Leukemia
Krali O, Enblad AP, Blom K, ..., Lönnerholm G, Nordlund J
Blood 142 (Supplement 1) 6064-6064 [2023-11-02; online 2023-11-02]
Mapping Chemo-Resistance Profiles of Pediatric Acute Leukemia through Integration of Ex-Vivo Drug Screens with Molecular Data
Enblad AP, Krali O, Blom K, ..., Lönnerholm G, Nordlund J
Blood 142 (Supplement 1) 1449-1449 [2023-11-02; online 2023-11-02]
Gut Microbial Dysbiosis in Myeloid Neoplasms: Correlations with Clinical and Genomic Features
Portlock T, Campagna A, Viviani F, ..., Della Porta MG, Shoaie S
Blood 142 (Supplement 1) 3216-3216 [2023-11-02; online 2023-11-02]
Genomic Determinants of Therapy Response in ETV6::RUNX1 Leukemia
Oksa L, Moisio S, Maqbool K, ..., Lohi O, Heinäniemi M
Blood 142 (Supplement 1) 2970-2970 [2023-11-02; online 2023-11-02]
Epigenetic Profiling and Machine Learning for Enhanced Risk Stratification in Pediatric Acute Lymphoblastic Leukemia
Mosquera Orgueira A, Krali O, Peleteiro Raindo A, ..., Schmiegelow K, Nordlund J
Blood 142 (Supplement 1) 4353-4353 [2023-11-02; online 2023-11-02]
3-D chromatin conformation, accessibility, and gene expression profiling of triple-negative breast cancer.
Llinàs-Arias P, Ensenyat-Méndez M, Orozco JIJ, ..., Lupien M, Marzese DM
BMC Genom Data 24 (1) 61 [2023-11-02; online 2023-11-02]
3D-printed sheet jet for stable megahertz liquid sample delivery at X-ray free-electron lasers.
Konold PE, You T, Bielecki J, ..., Westenhoff S, Maia FRNC
IUCrJ 10 (Pt 6) 662-670 [2023-11-01; online 2023-11-01]
The evolution of intramitochondriality in Midichloria bacteria.
Floriano AM, Batisti Biffignandi G, Castelli M, ..., Guy L, Sassera D
Environ. Microbiol. 25 (11) 2102-2117 [2023-11-00; online 2023-06-12]
Synthesis, Anti-inflammatory, and Neuroprotective Activity of N-Substituted Phthalimide Derivatives
Bhat MA, Ahmed AF, Wen ZH, ..., Naglah AM, Al-Omar MA
Russ J Gen Chem 93 (11) 2935-2940 [2023-11-00; online 2023-12-21]
Proline catabolism is a key factor facilitating Candida albicans pathogenicity.
Silao FGS, Jiang T, Bereczky-Veress B, ..., Peuckert C, Ljungdahl PO
PLoS Pathog 19 (11) e1011677 [2023-11-00; online 2023-11-02]
Monoclonal antibodies lock down SARS-CoV-2 spike.
Huang HC, Angeletti D
Trends Immunol. 44 (11) 874-876 [2023-11-00; online 2023-10-05]
Leveraging circulating microbial DNA for early cancer detection.
Kataria R, Shoaie S, Grigoriadis A, Wan JCM
Trends Cancer 9 (11) 879-882 [2023-11-00; online 2023-09-01]
VLDLR mediates alphavirus neuroinvasion through the blood-cerebrospinal fluid barrier
Martikainen M, Lugano R, Pietilä I, ..., Dimberg A, Essand M
- - (-) - [2023-10-30; online 2023-10-30]
Editorial: Understanding membrane transporters: from structure to function.
Pasquadibisceglie A, Bonaccorsi Di Patti MC, Miniero DV, Musci G, Polticelli F
Front Mol Biosci 10 (-) 1323824 [2023-10-30; online 2023-10-30]
Of mice and lymphoid aggregates: modeling tertiary lymphoid structures in cancer.
Vaccaro A, van de Walle T, Ramachandran M, Essand M, Dimberg A
Front Immunol 14 (-) 1275378 [2023-10-26; online 2023-10-26]
Multi-omics Quality Assessment in Personalized Medicine through EATRIS
Alonso-Andrés P, Baldazzi D, Chen Q, ..., Zheng Y, Žižkovičová P
- - (-) - [2023-10-26; online 2023-10-26]
Discovery of a novel inhibitor of macropinocytosis with antiviral activity
Porebski B, Christ W, Corman A, ..., Huhn D, Fernandez-Capetillo O
- - (-) - [2023-10-26; online 2023-10-26]
Automated model building and protein identification in cryo-EM maps.
Jamali K, Käll L, Zhang R, ..., Kimanius D, Scheres SHW
bioRxiv - (-) - [2023-10-17; online 2023-10-17]
Endothelial VEGFR2-PLCγ signaling regulates vascular permeability and antitumor immunity through eNOS/Src.
Sjöberg E, Melssen M, Richards M, ..., Dimberg A, Claesson-Welsh L
J. Clin. Invest. 133 (20) - [2023-10-16; online 2023-10-16]
Designing efficient randstrobes for sequence similarity analyses
Karami M, Mohammadi AS, Martin M, ..., Patro R, Sahlin K
- - (-) - [2023-10-16; online 2023-10-16]
Comment on bg-2023-147
- - (-) - [2023-10-16; online 2023-10-16]
Genetic ablation of adhesion ligands averts rejection of allogeneic immune cells.
Hammer Q, Perica K, van Ooijen H, ..., Sadelain M, Malmberg KJ
bioRxiv - (-) - [2023-10-09; online 2023-10-09]
Bacterial cell surface nanoenvironment requires a specialized chaperone to activate a peptidoglycan biosynthetic enzyme.
Delerue T, Chareyre S, Anantharaman V, ..., Aravind L, Ramamurthi KS
bioRxiv - (-) - [2023-10-06; online 2023-10-06]
A fluorophore-conjugated reagent enabling rapid detection, isolation and live tracking of senescent cells.
Magkouta S, Veroutis D, Pousias A, ..., Evangelou K, Gorgoulis VG
Mol. Cell 83 (19) 3558-3573.e7 [2023-10-05; online 2023-10-07]
Well-being spectrum traits are associated with polygenic scores for autism.
Mohammad S, de Ruijter MJT, Rukh G, ..., Mwinyi J, Schiöth HB
Autism Res 16 (10) 1891-1902 [2023-10-00; online 2023-08-21]
SPP1/osteopontin: a driver of fibrosis and inflammation in degenerative ascending aortic aneurysm?
Freiholtz D, Bergman O, Pradhananga S, ..., Eriksson P, Björck HM
J. Mol. Med. 101 (10) 1323-1333 [2023-10-00; online 2023-09-12]
SARS-CoV-2-related mortality decrease in nursing home residents given multiple COVID-19 boosters.
Blom K, Fjällström P, Molnár C, ..., Forsell MNE, Johansson AF
Lancet Infect Dis 23 (10) e393-e394 [2023-10-00; online 2023-09-13]
On the Path to Optimal Alchemistry.
Lundborg M, Lidmar J, Hess B
Protein J 42 (5) 477-489 [2023-10-00; online 2023-08-31]
Methods to Discover and Validate Biofluid-Based Biomarkers in Neurodegenerative Dementias.
Teunissen CE, Kimble L, Bayoumy S, ..., Zetterberg H, MIRIADE consortium
Mol. Cell Proteomics 22 (10) 100629 [2023-10-00; online 2023-08-07]
Distinct HLA associations with autoantibody-defined subgroups in idiopathic inflammatory myopathies.
Leclair V, Galindo-Feria AS, Rothwell S, ..., Lundberg IE, Diaz-Gallo LM
EBioMedicine 96 (-) 104804 [2023-10-00; online 2023-09-26]
Blood Proteins are Associated with Aneurysm Growth in Men with Screening Detected Abdominal Aortic Aneurysm
Siika A, Edfors F, Obeberg J, ..., Hultgren R, Roy J
Aorta (Stamford) 11 (05) 1-18 [2023-10-00; online 2024-06-11]
Exploring the morphology of the host cell to open new possibilities for drug repurposing in viral infections
Tampere M, Kalman A, Rietdijk J, ..., Stadler C, Östling P
- - (-) - [2023-09-28; online 2023-09-28]
Building the next generation of virtual cells to understand cellular biology.
Johnson GT, Agmon E, Akamatsu M, ..., Rafelski S, Horwitz R
Biophys. J. 122 (18) 3560-3569 [2023-09-19; online 2023-04-11]
Epigenetic coordination of transcriptional and translational programs in hypoxia
Watt K, Dauber B, Szkop KJ, ..., Larsson O, Postovit LM
- - (-) - [2023-09-17; online 2023-09-17]
Enhancing European capabilities for application of multi-omics studies in biology and biomedicine space research.
Manzano A, Weging S, Bezdan D, ..., da Silveira WA, Herranz R
iScience 26 (9) 107289 [2023-09-15; online 2023-07-12]
Identifying genetic regulatory variants that affect transcription factor activity.
Li X, Lappalainen T, Bussemaker HJ
Cell Genom 3 (9) 100382 [2023-09-13; online 2023-08-18]
Photoinduced Ring-Opening and Phototoxicity of an Indolin-3-one Derivative.
Doloczki S, Kern C, Holmberg KO, ..., Streuff J, Dyrager C
Chemistry 29 (51) e202300864 [2023-09-12; online 2023-08-09]
A novel kleptoplastidic symbiosis revealed in the marine centrohelid Meringosphaera with evidence of genetic integration.
Sørensen MES, Zlatogursky VV, Onuţ-Brännström I, ..., Foster RA, Burki F
Curr. Biol. 33 (17) 3571-3584.e6 [2023-09-11; online 2023-08-02]
Fabien Burki SciLifeLab Fellow
PI-(3,5)P2-mediated oligomerization of the endosomal sodium/proton exchanger NHE9
Kokane S, Meier PF, Gulati A, ..., Fuster D, Drew D
- - (-) - [2023-09-10; online 2023-09-10]
CCG-1423-derived compounds reduce global RNA synthesis and inhibit transcriptional responses
Prajapati B, Sokolova M, Sidorenko E, ..., Vihervaara A, Vartiainen MK
- - (-) - [2023-09-08; online 2023-09-08]
Long-term longitudinal analysis of 4,187 participants reveals new insights into determinants of incident clonal hematopoiesis.
Uddin MM, Saadatagah S, Niroula A, ..., Ballantyne CM, Natarajan P
medRxiv - (-) - [2023-09-07; online 2023-09-07]
Continental scientific drilling and microbiology: (extremely) low biomass in crystalline bedrock of central Sweden
Westmeijer G, Escudero C, Bergin C, ..., Bertilsson S, Dopson M
- - (-) - [2023-09-07; online 2023-09-07]
Advanced variant classification framework reduces the false positive rate of predicted loss-of-function variants in population sequencing data.
Singer-Berk M, Gudmundsson S, Baxter S, ..., Rehm HL, O'Donnell-Luria A
Am. J. Hum. Genet. 110 (9) 1496-1508 [2023-09-07; online 2023-08-25]
A test of memory for stimulus sequences in great apes.
Lind J, Vinken V, Jonsson M, Ghirlanda S, Enquist M
PLoS ONE 18 (9) e0290546 [2023-09-06; online 2023-09-06]
Influenza virus decreases albumin uptake and megalin expression in alveolar epithelial cells.
Alberro-Brage A, Kryvenko V, Malainou C, ..., Samakovlis C, Vadász I
Front Immunol 14 (-) 1260973 [2023-09-01; online 2023-09-01]
Whole tumour cell-based vaccines: tuning the instruments to orchestrate an optimal antitumour immune response.
Pérez-Baños A, Gleisner MA, Flores I, ..., Tittarelli A, Salazar-Onfray F
Br. J. Cancer 129 (4) 572-585 [2023-09-00; online 2023-06-24]
The understory microclimate in agroforestry now and in the future – a case study of Arabica coffee in its native range
Zignol F, Kjellström E, Hylander K, ..., Rodríguez-Gijón A, Tack AJM
Agricultural and Forest Meteorology 340 (-) 109586 [2023-09-00; online 2023-09-00]
Laboratory evolution of Synechocystis sp. PCC 6803 for phenylpropanoid production.
Kukil K, Englund E, Crang N, Hudson EP, Lindberg P
Metab. Eng. 79 (-) 27-37 [2023-09-00; online 2023-06-29]
Immune system adaptation during gender-affirming testosterone treatment
Consiglio C, Tadepally L, Sardh F, ..., Landegren N, Brodin P
Journal of Reproductive Immunology 159 (-) 104065 [2023-09-00; online 2023-09-00]
Ghost admixture in eastern gorillas.
Pawar H, Rymbekova A, Cuadros-Espinoza S, ..., Marques-Bonet T, Kuhlwilm M
Nat Ecol Evol 7 (9) 1503-1514 [2023-09-00; online 2023-07-27]
GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification.
Lagou V, Jiang L, Ulrich A, ..., Prokopenko I, Meta-Analysis of Glucose and Insulin-Related Traits Consortium (MAGIC)
Nat. Genet. 55 (9) 1448-1461 [2023-09-00; online 2023-09-07]
Ex Vivo Drug Testing in Patient-derived Papillary Renal Cancer Cells Reveals EGFR and the BCL2 Family as Therapeutic Targets.
Angori S, Banaei-Esfahani A, Mühlbauer K, ..., Schraml P, Moch H
Eur Urol Focus 9 (5) 751-759 [2023-09-00; online 2023-03-16]
Image-based and machine learning-guided multiplexed serology test for SARS-CoV-2.
Pietiäinen V, Polso M, Migh E, ..., Horvath P, Hepojoki J
Cell Rep Methods 3 (8) 100565 [2023-08-28; online 2023-08-22]
Association of mitochondrial DNA copy number with chronic kidney disease in older adults.
Liu Y, Pan Y, Tian Z, ..., Zhou X, Zhou K
BMC Geriatr 23 (1) 514 [2023-08-24; online 2023-08-24]
Complex Polyploids: Origins, Genomic Composition, and Role of Introgressed Alleles
Leal JL, Milesi P, Hodková E, ..., Salojärvi J, Lascoux M
- - (-) - [2023-08-23; online 2023-08-23]
Publisher Correction: A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.
Ladds MJGW, van Leeuwen IMM, Drummond CJ, ..., McCormack E, Laín S
Nat Commun 14 (1) 5019 [2023-08-18; online 2023-08-18]
Single-cell spatial transcriptome reveals cell-type organization in the macaque cortex.
Chen A, Sun Y, Lei Y, ..., Xu X, Li C
Cell 186 (17) 3726-3743.e24 [2023-08-17; online 2023-07-12]
Association of the human gut microbiota with vascular stiffness.
Cuadrat RRC, Goris T, Birukov A, ..., Wittenbecher C, Schulze MB
Sci Rep 13 (1) 13348 [2023-08-16; online 2023-08-16]
Clemens Wittenbecher DDLS Fellow
Using evolutionary constraint to define novel candidate driver genes in medulloblastoma.
Roy A, Sakthikumar S, Kozyrev SV, ..., Lindblad-Toh K, Forsberg-Nilsson K
Proc. Natl. Acad. Sci. U.S.A. 120 (33) e2300984120 [2023-08-15; online 2023-08-07]
Nucleolar stress caused by arginine-rich peptides triggers a ribosomopathy and accelerates ageing in mice
Sirozh O, Jung B, Sanchez-Burgos L, ..., Lafarga V, Fernández-Capetillo O
- - (-) - [2023-08-11; online 2023-08-11]
Local excision versus thrombectomy in thrombosed external hemorrhoids: a multicenter, prospective, observational study.
Yalcinkaya A, Yalcinkaya A, Atici SD, ..., Leventoglu S, T E H Study Collaboration
BMC Surg 23 (1) 228 [2023-08-10; online 2023-08-10]
Multiset correlation and factor analysis enables exploration of multi-omics data.
Brown BC, Wang C, Kasela S, ..., Knowles DA, Lappalainen T
Cell Genom 3 (8) 100359 [2023-08-09; online 2023-07-10]
Folded alpha helical putative new proteins from Apilactobacillus kunkeei
Ye W, Behra PRK, Dyrhage K, ..., Andersson SGE, Jemth P
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Technology platform for facile handling of 3D hydrogel cell culture scaffolds.
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The salivary microbiota is altered in cervical dysplasia patients and influenced by conization.
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Spatial transcriptomics of human placentas reveal distinct RNA patterns associated with morphology and preeclampsia.
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Placenta 139 (-) 213-216 [2023-08-00; online 2023-07-05]
S154: IDENTIFICATION OF NOVEL FACTORS CONTROLLING NON GENETIC CELL PLASTICITY IN CHRONIC MYELOID LEUKEMIA
Baselli G, Alekseenko A, Brinkman E, ..., Sinanis L, Pelechano V
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Polygenic risk scores and risk stratification in deep vein thrombosis.
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PB1709: A COMPLETE DIGITAL KARYOTYPE OF THE B-CELL LEUKEMIA REH CELL LINE RESOLVED BY LONG-READ SEQUENCING
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OSA Is Associated With the Human Gut Microbiota Composition and Functional Potential in the Population-Based Swedish CardioPulmonary bioImage Study.
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Mucosal IgA protects against BQ.1 and BQ.1.1 infection.
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Lancet Infect Dis 23 (8) e272-e273 [2023-08-00; online 2023-07-12]
Expansion spatial transcriptomics.
Fan Y, Andrusivová Ž, Wu Y, ..., Lundeberg J, Wang B
Nat. Methods 20 (8) 1179-1182 [2023-08-00; online 2023-06-22]
Cystathionine gamma-lyase (CTH) inhibition attenuates glioblastoma formation.
Peleli M, Antoniadou I, Rodrigues-Junior DM, ..., Moustakas A, Papapetropoulos A
Redox Biol 64 (-) 102773 [2023-08-00; online 2023-06-05]
Microaerobic degradation of crude oil and long chain alkanes by a new Rhodococcus strain from Gulf of Mexico.
Juárez K, Reza L, Bretón-Deval L, ..., García-Guevara F, Lara P
World J Microbiol Biotechnol 39 (10) 264 [2023-07-29; online 2023-07-29]
Delineating functional and molecular impact of ex vivo sample handling in precision medicine
Erkers T, Struyf N, Arnroth C, ..., Kallioniemi O, Seashore-Ludlow B
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Moving beyond the desktop: prospects for practical bioimage analysis via the web.
Ouyang W, Eliceiri KW, Cimini BA
Front Bioinform 3 (-) 1233748 [2023-07-25; online 2023-07-25]
Identification of ATF3 as a novel protective signature of quiescent colorectal tumor cells
Zhang X, Lu X, Zhong L, ..., Chen X, Sjoblom T
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A Molecular Basis of Human Brain Connectivity.
Ng B, Tasaki S, Greathouse KM, ..., Gaiteri C, Herskowitz JH
bioRxiv - (-) - [2023-07-24; online 2023-07-24]
Novel CSF tau biomarkers can be used for disease staging of sporadic Alzheimer's disease.
Salvadó G, Horie K, Barthélemy NR, ..., Bateman RJ, Hansson O
medRxiv - (-) - [2023-07-16; online 2023-07-16]
InParanoiDB 9: Ortholog Groups for Protein Domains and Full-Length Proteins.
Persson E, Sonnhammer ELL
J. Mol. Biol. 435 (14) 168001 [2023-07-15; online 2023-02-09]
The Escherichia coli chromosome moves to the replisome
Gras K, Fange D, Elf J
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N-Glycomic Profiling of Microsatellite Unstable Colorectal Cancer.
Ukkola I, Nummela P, Heiskanen A, ..., Kytölä S, Ristimäki A
Cancers (Basel) 15 (14) - [2023-07-11; online 2023-07-11]
Automated simulation-based membrane protein refinement into cryo-EM data.
Yvonnesdotter L, Rovšnik U, Blau C, ..., Howard RJ, Lindahl E
Biophys. J. 122 (13) 2773-2781 [2023-07-11; online 2023-06-05]
A Career in Catalysis: Bernhard Hauer
Nebel BA, Breuer M, Schneider A, ..., Weissenborn MJ, Nestl BM
ACS Catal 13 (13) 8861-8889 [2023-07-07; online 2023-06-20]
Sex-specific microglia state in the Neuroligin-4 knock-out mouse model of autism spectrum disorder.
Guneykaya D, Ugursu B, Logiacco F, ..., Kettenmann H, Wolf SA
Brain Behav. Immun. 111 (-) 61-75 [2023-07-00; online 2023-03-29]
Mucosal immune responses following a fourth SARS-CoV-2 vaccine dose.
Bladh O, Marking U, Havervall S, ..., Klingström J, Thålin C
Lancet Microbe 4 (7) e488 [2023-07-00; online 2023-04-20]
Cannabis-derived products antagonize platinum drugs by altered cellular transport.
Buchtova T, Beresova L, Chroma K, ..., Bartek J, Mistrik M
Biomed. Pharmacother. 163 (-) 114801 [2023-07-00; online 2023-05-01]
Interaction molecular QTL mapping discovers cellular and environmental modifiers of genetic regulatory effects.
Kasela S, Aguet F, Kim-Hellmuth S, ..., Graham Barr R, Lappalainen T
bioRxiv - (-) - [2023-06-29; online 2023-06-29]
In vitro models to study natural killer cell dynamics in the tumor microenvironment.
Carannante V, Wiklund M, Önfelt B
Front Immunol 14 (-) 1135148 [2023-06-28; online 2023-06-28]
Persistent immunosuppressive effects of dibutyl phthalate exposure in adult male mice.
Pierozan P, Källsten L, Theodoropoulou E, Almamoun R, Karlsson O
Sci. Total Environ. 878 (-) 162741 [2023-06-20; online 2023-03-11]
Oskar Karlsson SciLifeLab Fellow
Loss of chromosome Y in regulatory T cells
Mattisson J, Halvardson J, Davies H, ..., Dumanski JP, Forsberg LA
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Letter to the editor.
Soussi T
Hum. Mol. Genet. 32 (13) 2121-2123 [2023-06-19; online 2023-03-11]
Zfp697 is an RNA-binding protein that regulates skeletal muscle inflammation and regeneration.
Correia JC, Jannig PR, Gosztyla ML, ..., Yeo GW, Ruas JL
bioRxiv - (-) - [2023-06-13; online 2023-06-13]
Population-based cohort study of oral contraceptive use and risk of depression.
Johansson T, Vinther Larsen S, Bui M, ..., Karlsson T, Johansson Å
Epidemiol Psychiatr Sci 32 (-) e39 [2023-06-12; online 2023-06-12]
Orthogonal proteomics methods warrant the development of Duchenne muscular dystrophy biomarkers.
Johansson C, Hunt H, Signorelli M, ..., Uhlén M, Szigyarto CA
Clin Proteomics 20 (1) 23 [2023-06-12; online 2023-06-12]
Adiposity and sex-specific cancer risk.
Rask-Andersen M, Ivansson E, Höglund J, ..., Karlsson T, Johansson Å
Cancer Cell 41 (6) 1186-1197.e4 [2023-06-12; online 2023-06-14]
Deconvolution of spatial sequencing provides accurate characterization of hESC-derived DA transplants in vivo.
Rájová J, Davidsson M, Avallone M, ..., Parmar M, Björklund T
Mol Ther Methods Clin Dev 29 (-) 381-394 [2023-06-08; online 2023-05-04]
The full spectrum of OCT1 (SLC22A1) mutations bridges transporter biophysics to drug pharmacogenomics.
Yee SW, Macdonald C, Mitrovic D, ..., Giacomini KM, Coyote-Maestas W
bioRxiv - (-) - [2023-06-07; online 2023-06-07]
Elevated plasma complement factor H related 5 protein is associated with venous thromboembolism.
Iglesias MJ, Sanchez-Rivera L, Ibrahim-Kosta M, ..., Trégouët DA, Odeberg J
Nat Commun 14 (1) 3280 [2023-06-07; online 2023-06-07]
Engineered display of ganglioside-sugars on protein elicits a clonally and structurally constrained B cell response
Deimel LP, Xue X, Khan A, ..., Davis BG, Sattentau QJ
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Temporal transcriptome analysis of the endothelial response to tumour necrosis factor
Struck E, Belova T, Hsieh P, ..., Dusart P, Butler L
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Evaluation of plasma Short chain fatty acid levels as markers for Inflammatory bowel disease.
Kiasat A, Rautiainen S, Prast-Nielsen S, ..., Gustafsson UO, Löf Granström A
Scand. J. Gastroenterol. 58 (11) 1246-1252 [2023-06-05; online 2023-06-05]
Abstract A051: The spatial landscape of clonal somatic copy number alterations in benign and malignant prostate epithelia
Erickson A, He M, Berglund E, ..., Lamb AD, Lundeberg J
Cancer Res. 83 (11_Supplement) A051-A051 [2023-06-02; online 2023-06-02]
Reply to: Obsessive-Compulsive Disorder, Tic Disorders, and Early-Life Infections.
Zhang T, Brander G, Isung J, ..., Mataix-Cols D, Fernández de la Cruz L
Biol. Psychiatry 93 (11) e37-e38 [2023-06-01; online 2022-12-09]
Obesity-induced inflammation exacerbates clonal hematopoiesis.
Pasupuleti SK, Ramdas B, Burns SS, ..., Natarajan P, Kapur R
J. Clin. Invest. 133 (11) - [2023-06-01; online 2023-06-01]
Abhishek Niroula DDLS Fellow
The Long Noncoding RNA LINC00958 Is Induced in Psoriasis Epidermis and Modulates Epidermal Proliferation.
Luo L, Pasquali L, Srivastava A, ..., Pivarcsi A, Sonkoly E
J. Invest. Dermatol. 143 (6) 999-1010 [2023-06-00; online 2023-01-12]
Relation of different CSF biosignatures to clinical phenotypes in a memory clinic cohort
Alanko V, Mravinacová S, Kivipelto M, ..., Nilsson P, Sandebring‐Matton A
Alzheimers Dement 19 (S2) - [2023-06-00; online 2023-06-16]
POS1438 ANALYSIS OF THE PLASMA PROTEOME PROVIDES MECHANISTIC INSIGHTS INTO THE PATHOPHYSIOLOGY OF ANCA-ASSOCIATED VASCULITIS
Hellbacher E, Van Hoef V, Johansson A, ..., Rantapää Dahlqvist S, Dahlqvist J
Ann Rheum Dis 82 (-) 1073 [2023-06-00; online 2023-06-00]
POS0603 AUTOANTIBODIES AGAINST A SUBUNIT OF MITOCHONDRIAL RESPIRATORY CHAIN COMPLEX I IN INCLUSION BODY MYOSITIS
Notarnicola A, Hellstrom C, Horuluoglu B, ..., Nilsson P, Lundberg IE
Ann Rheum Dis 82 (-) 574 [2023-06-00; online 2023-06-00]
OxLDL sensitizes platelets for increased formation of extracellular vesicles capable of finetuning macrophage gene expression.
Maaninka K, Neuvonen M, Kerkelä E, ..., Öörni K, Siljander PR
Eur J Cell Biol 102 (2) 151311 [2023-06-00; online 2023-03-15]
OP0021 STRATIFICATION OF PATIENTS WITH SJÖGREN'S SYNDROME BY JOINT MULTI-MODAL ANALYSIS OF CIRCULATING B CELLS
Arvidsson G, Czarnewski P, Johansson A, ..., Nordmark G, Syvänen AC
Ann Rheum Dis 82 (-) 13-14 [2023-06-00; online 2023-06-00]
Mobility and the spatial spread of sars-cov-2 in Belgium.
Rollier M, Miranda GHB, Vergeynst J, ..., Belgian Collaborative Group on covid-19 Hospital Surveillance , Baetens JM
Math Biosci 360 (-) 108957 [2023-06-00; online 2023-02-17]
Gisele Miranda SciLifeLab Fellow
In situ architecture of the ER-mitochondria encounter structure.
Wozny MR, Di Luca A, Morado DR, ..., Vanni S, Kukulski W
Nature 618 (7963) 188-192 [2023-06-00; online 2023-05-10]
Diagnostic Yield From a Nationwide Implementation of Precision Medicine for all Children With Cancer.
Wadensten E, Wessman S, Abel F, ..., Gisselsson D, Genomic Medicine Sweden Childhood Cancer Working Group
JCO Precis Oncol 7 (-) e2300039 [2023-06-00; online 2023-06-29]
Comparison of two supporting matrices for patient-derived cancer cells in 3D drug sensitivity and resistance testing assay (3D-DSRT).
Feodoroff M, Mikkonen P, Turunen L, ..., Kallioniemi O, Pietiäinen V
SLAS Discov 28 (4) 138-148 [2023-06-00; online 2023-03-20]
The impact of TLR2 and aging on the humoral immune response to Staphylococcus aureus bacteremia in mice.
Gupta P, Hu Z, Kopparapu PK, ..., Jin T, Engdahl C
Sci Rep 13 (1) 8850 [2023-05-31; online 2023-05-31]
Spatially resolved multiomics on the neuronal effects induced by spaceflight
Masarapu Y, Cekanaviciute E, Andrusivova Z, ..., Costes S, Giacomello S
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Targeting NETs using dual-active DNase1 variants.
Englert H, Göbel J, Khong D, ..., Fuchs TA, Renné T
Front Immunol 14 (-) 1181761 [2023-05-23; online 2023-05-23]
Membranes in focus.
Sezgin E, Levental I
Biophys. J. - (-) - [2023-05-19; online 2023-05-19]
Erdinc Sezgin SciLifeLab Fellow
Rapid Traversal of Ultralarge Chemical Space using Machine Learning Guided Docking Screens
Luttens A, Cabeza de Vaca I, Sparring L, Norinder U, Carlsson J
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Plasma protein changes reflect colorectal cancer development and associated inflammation.
Urbiola-Salvador V, Jabłońska A, Miroszewska D, ..., Li B, Chen Z
Front Oncol 13 (-) 1158261 [2023-05-09; online 2023-05-09]
Ball-and-Chain Inactivation in Potassium Channels.
Sukomon N, Fan C, Nimigean CM
Annu Rev Biophys 52 (-) 91-111 [2023-05-09; online 2023-01-10]
Lab-in-a-fiber-based integrated particle separation and counting.
Kumar T, Harish AV, Etcheverry S, ..., Laurell F, Russom A
Lab Chip 23 (9) 2286-2293 [2023-05-02; online 2023-05-02]
Chiropterans Are a Hotspot for Horizontal Transfer of DNA Transposons in Mammalia.
Paulat NS, Storer JM, Moreno-Santillán DD, ..., Karlsson EK, Ray DA
Mol. Biol. Evol. 40 (5) - [2023-05-02; online 2023-04-18]
Modelling Brain in a Chip.
Ashammakhi N, Nasiri R, Contag CH, Herland A
J Craniofac Surg 34 (3) 845-847 [2023-05-01; online 2023-03-24]
Anti-IL-6R prevents experimental type 1 diabetes
Luo Z, Hamze N, Berggren E, ..., Sandler S, Singh K
J. Immunol. 210 (Supplement_1) 165.20-165.20 [2023-05-01; online 2023-05-01]
The association between genetically elevated polyunsaturated fatty acids and risk of cancer.
Haycock PC, Borges MC, Burrows K, ..., Martin RM, Fatty Acids in Cancer Mendelian Randomization Collaboration
EBioMedicine 91 (-) 104510 [2023-05-00; online 2023-04-20]
Prediction of risk for myeloid malignancy in clonal hematopoiesis.
Weeks LD, Niroula A, Neuberg D, ..., Natarajan P, Ebert BL
NEJM Evid 2 (5) - [2023-05-00; online 2023-04-25]
Abhishek Niroula DDLS Fellow
Plasma lipidome and risk of atrial fibrillation: results from the PREDIMED trial.
Toledo E, Wittenbecher C, Razquin C, ..., Hu FB, Martínez-González MA
J Physiol Biochem 79 (2) 355-364 [2023-05-00; online 2023-04-01]
Clemens Wittenbecher DDLS Fellow
Naturally occurring dipeptide from elite controllers with dual anti-HIV-1 mechanism.
Ceña-Diez R, Narayanan A, Ray S, ..., van Domselaar R, Sönnerborg A
Int. J. Antimicrob. Agents 61 (5) 106792 [2023-05-00; online 2023-03-15]
Itch receptor MRGPRX4 interacts with the receptor activity-modifying proteins.
Kotliar IB, Ceraudo E, Kemelmakher-Liben K, ..., Schwenk JM, Sakmar TP
J Biol Chem 299 (5) 104664 [2023-05-00; online 2023-03-30]
Insulin thermostability in a real-world setting.
Pendsey S, James S, Garrett TJ, ..., Forsander G, Ogle GD
The Lancet Diabetes & Endocrinology 11 (5) 310-312 [2023-05-00; online 2023-03-29]
Hepatic Innervations and Nonalcoholic Fatty Liver Disease.
Adori M, Bhat S, Gramignoli R, ..., Uhlèn M, Adori C
Semin Liver Dis 43 (2) 149-162 [2023-05-00; online 2023-05-08]
Cotranslational folding of human growth hormone in vitro and in Escherichia coli.
Mermans D, Nicolaus F, Baygin A, von Heijne G
FEBS Lett. 597 (10) 1355-1362 [2023-05-00; online 2022-12-22]
Conditionally activated affibody-based prodrug targeting EGFR demonstrates improved tumour selectivity.
Dahlsson Leitao C, Mestre Borras A, Xu T, ..., Vorobyeva A, Löfblom J
J Control Release 357 (-) 185-195 [2023-05-00; online 2023-03-31]
Mapping of the gene network that regulates glycan clock of ageing
Frkatović-Hodžić A, Miškec K, Mijakovac A, ..., Zoldoš V, Lauc G
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Genomic, transcriptomic and epigenomic sequencing data of the B- cell leukemia cell line REH
Wiklander ML, Övernäs E, Lagensjö J, ..., Liljedahl U, Nordlund J
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Size matters: the impact of nucleus size on results from spatial transcriptomics.
Mohammadi E, Chojnowska K, Bieńkowski M, ..., Piotrowski A, Mieczkowski J
J Transl Med 21 (1) 270 [2023-04-21; online 2023-04-21]
Development of top-down cortical propagations in youth.
Pines A, Keller AS, Larsen B, ..., Fair DA, Satterthwaite TD
Neuron 111 (8) 1316-1330.e5 [2023-04-19; online 2023-02-17]
DDLS Fellow Jacob W Vogel
ERβ in Granulosa Cell Tumors and Its Clinical Potential.
Birgersson M, Indukuri R, Antonson P, ..., Archer A, Williams C
Endocrinology 164 (6) - [2023-04-17; online 2023-04-19]
Abstract LB362: Epigenome-wide DNA methylation alterations precede diagnosis since birth and affect prognosis of pediatric B-cell acute lymphoblastic leukemia
Ghantous A, Nusslé SG, Nassar F, ..., Munthe-Kaas MC, Herceg Z
Cancer Res. 83 (8_Supplement) LB362-LB362 [2023-04-14; online 2023-04-14]
M-Ionic: Prediction of metal ion binding sites from sequence using residue embeddings
Shenoy A, Kalakoti Y, Sundar D, Elofsson A
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Abstract 705: Potentiation of immunotherapy by LSD1 modulation
Emond WB, Sawant R, Geitmann M, ..., Hellström M, Koehler KF
Cancer Res. 83 (7_Supplement) 705-705 [2023-04-04; online 2023-04-04]
Abstract 1793: Single-cell RNA analysis reveal effector-like CD8+ CAR-T cell subpopulations associated with response in lymphoma patients
Sarén T, Ramachandran M, Gammelgård G, ..., Enblad G, Essand M
Cancer Res. 83 (7_Supplement) 1793-1793 [2023-04-04; online 2023-04-04]
IL-1 receptor-associated kinase-3 acts as an immune checkpoint in myeloid cells to limit cancer immunotherapy.
Tunalı G, Rúbies Bedós M, Nagarajan D, ..., Papakyriacou I, Mao Y
J. Clin. Invest. 133 (7) - [2023-04-03; online 2023-04-03]
Optimizing insect metabarcoding using replicated mock communities.
Iwaszkiewicz-Eggebrecht E, Granqvist E, Buczek M, ..., Ronquist F, Łukasik P
Methods Ecol Evol 14 (4) 1130-1146 [2023-04-00; online 2023-02-13]
Novel therapeutic approaches for pleural mesothelioma identified by functional ex vivo drug sensitivity testing.
Ollila-Raj H, Murumägi A, Pellinen T, ..., Mäyränpää MI, Ilonen I
Lung Cancer 178 (-) 213-219 [2023-04-00; online 2023-03-01]
Heterologous inactivated virus/mRNA vaccination response to BF.7, BQ.1.1, and XBB.1.
Zuo F, Sun R, Abolhassani H, ..., Marcotte H, Pan-Hammarström Q
Lancet Reg Health West Pac 33 (-) 100762 [2023-04-00; online 2023-04-12]
CD93 maintains endothelial barrier function by limiting the phosphorylation and turnover of VE-cadherin.
Lugano R, Vemuri K, Barbera S, ..., Claesson-Welsh L, Dimberg A
FASEB J. 37 (4) e22894 [2023-04-00; online 2023-03-25]
Data from <i>SETD2</i> Is Recurrently Mutated in Whole-Exome Sequenced Canine Osteosarcoma
Sakthikumar S, Elvers I, Kim J, ..., Marinescu VD, Lindblad-Toh K
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Data from <i>SETD2</i> Is Recurrently Mutated in Whole-Exome Sequenced Canine Osteosarcoma
Sakthikumar S, Elvers I, Kim J, ..., Marinescu VD, Lindblad-Toh K
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Data from 6-Thioguanine Selectively Kills BRCA2-Defective Tumors and Overcomes PARP Inhibitor Resistance
Issaeva N, Thomas HD, Djurenovic T, ..., Curtin NJ, Helleday T
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Chiropterans are a hotspot for horizontal transfer of DNA transposons in Mammalia
Paulat NS, Storer JM, Moreno-Santillán DD, ..., Karlsson EK, Ray DA
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PD-L1ATTAC mice reveal the potential of depleting PD-L1 expressing cells in cancer therapy.
Fueyo-Marcos E, Lopez-Pernas G, Fustero-Torre C, ..., Fernández-Capetillo O, Murga M
Aging (Albany NY) 15 (6) 1791-1807 [2023-03-22; online 2023-03-22]
Targeting Glioblastoma-Associated Macrophages for Photodynamic Therapy Using AGuIX®-Design Nanoparticles.
Lerouge L, Gries M, Chateau A, ..., Thomas N, Barberi-Heyob M
Pharmaceutics 15 (3) - [2023-03-20; online 2023-03-20]
Amino acid usage and tRNA expression underlies proteome adaptation in Plasmodium falciparum
Li Q, Vetter L, Veith Y, ..., Larsson O, Chan SCL
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Transcript Isoform Diversity of Ampliconic Genes on the Y Chromosome of Great Apes.
Tomaszkiewicz M, Sahlin K, Medvedev P, Makova KD
bioRxiv - (-) - [2023-03-18; online 2023-03-18]
Structural Elucidation of Ivermectin Binding to α7nAChR and the Induced Channel Desensitization.
Bondarenko V, Chen Q, Singewald K, ..., Xu Y, Tang P
ACS Chem Neurosci 14 (6) 1156-1165 [2023-03-15; online 2023-02-23]
A positive feedback loop driven by fibronectin and IL-1β sustains the inflammatory microenvironment in breast cancer.
Tunali G, Yanik H, Ozturk SC, ..., Van Obberghen-Schilling E, Esendagli G
Breast Cancer Res. 25 (1) 27 [2023-03-15; online 2023-03-15]
Heparanase Modulates Chromatin Accessibility.
Li H, Zhang H, Wenz A, ..., Chen X, Li J
Cells 12 (6) - [2023-03-14; online 2023-03-14]
The Drug Repurposing Encyclopedia (DRE): a web server for systematic drug repurposing across 20 organisms
Li X, Pan L, Sanchez-Burgos L, Hühn D, Fernandez-Capetillo O
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Leveraging Base Pair Mammalian Constraint to Understand Genetic Variation and Human Disease.
Sullivan PF, Meadows JRS, Gazal S, ..., Karlsson EK, Lindblad-Toh K
bioRxiv - (-) - [2023-03-10; online 2023-03-10]
Inference and reconstruction of the heimdallarchaeial ancestry of eukaryotes
Eme L, Tamarit D, Caceres EF, ..., Baker BJ, Ettema TJG
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Evolutionary constraint and innovation across hundreds of placental mammals
Christmas MJ, Kaplow IM, Genereux DP, ..., Lindblad-Toh K, Karlsson EK
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An intracellular hydrophobic nexus is critical for slow deactivation in hERG channels
Stevens-Sostre WA, Flores-Aldama L, Bustos D, ..., Delemotte L, Robertson GA
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Targeting the nucleolus as a therapeutic strategy in human disease.
Corman A, Sirozh O, Lafarga V, Fernandez-Capetillo O
Trends Biochem. Sci. 48 (3) 274-287 [2023-03-00; online 2022-10-10]
Protocol for 3D drug sensitivity and resistance testing of patient-derived cancer cells in 384-well plates.
Feodoroff M, Mikkonen P, Arjama M, ..., Turunen L, Pietiäinen V
SLAS Discov 28 (2) 36-41 [2023-03-00; online 2022-12-01]
Palidis: fast discovery of novel insertion sequences.
Carr VR, Pissis SP, Mullany P, ..., Gomez-Cabrero D, Moyes DL
Microb Genom 9 (3) - [2023-03-00; online 2023-03-11]
Exosomes: A missing link between chronic systemic inflammation and Alzheimer's disease?
Ozansoy M, Mikati H, Velioglu HA, Yulug B
Biomed. Pharmacother. 159 (-) 114161 [2023-03-00; online 2023-01-13]
Comparison of HER2-targeted affibody conjugates loaded with auristatin- and maytansine-derived drugs.
Yin W, Xu T, Ding H, ..., Gräslund T, Vorobyeva A
J Control Release 355 (-) 515-527 [2023-03-00; online 2023-02-14]
An open-source microscopy framework for simultaneous control of image acquisition, reconstruction, and analysis.
Casas Moreno X, Silva MM, Roos J, ..., Norlin N, Testa I
HardwareX 13 (-) e00400 [2023-03-00; online 2023-02-06]
African Farmers, Not Stone Age Foragers: Reassessment of Human Remains from the Mumbwa Caves, Zambia
Steyn M, Meyer A, Peyroteo-Stjerna R, ..., Barham L, Lombard M
Afr Archaeol Rev 40 (1) 53-72 [2023-03-00; online 2022-12-14]
A Microfluidic Contact Lens to Address Contact Lens-Induced Dry Eye.
Zhu Y, Nasiri R, Davoodi E, ..., Toyserkani E, Khademhosseini A
Small 19 (11) e2207017 [2023-03-00; online 2022-12-23]
A 3D Bioprinted Gut Anaerobic Model for Studying Bacteria-Host Interactions.
Cheng L, Liu T, Liu Q, ..., Zhang YS, Du J
Research (Wash D C) 6 (-) 0058 [2023-02-27; online 2023-02-27]
Amyloid-β accumulation in human astrocytes induces mitochondrial disruption and changed energy metabolism.
Zyśk M, Beretta C, Naia L, ..., Ankarcrona M, Erlandsson A
J Neuroinflammation 20 (1) 43 [2023-02-20; online 2023-02-20]
Antisecretory factor is safe to use as add-on treatment in newly diagnosed glioblastoma.
Ehinger E, Kopecky J, Darabi A, ..., Bengzon J, Siesjö P
BMC Neurol 23 (1) 76 [2023-02-18; online 2023-02-18]
Phenotypic screening platform identifies statins as enhancers of immune cell-induced cancer cell death.
Selvin T, Berglund M, Lenhammar L, ..., Larsson R, Andersson CR
BMC Cancer 23 (1) 164 [2023-02-17; online 2023-02-17]
Generation of tumor spheroids in microwells to study NK cell cytotoxicity, infiltration and phenotype.
Carannante V, Sandström N, Olofsson K, ..., Wiklund M, Önfelt B
Methods Cell Biol 178 (-) 195-208 [2023-02-16; online 2023-02-16]
Population Genomics for Insect Conservation.
Webster MT, Beaurepaire A, Neumann P, Stolle E
Annu Rev Anim Biosci 11 (-) 115-140 [2023-02-15; online 2022-11-14]
When Two Become One: Conformational Changes in FXR/RXR Heterodimers Bound to Steroidal Antagonists.
Díaz-Holguín A, Rashidian A, Pijnenburg D, ..., Pavek P, Kronenberger T
ChemMedChem 18 (4) e202200556 [2023-02-14; online 2022-11-30]
Genetic mechanisms of 184 neuro-related proteins in human plasma.
Repetto L, Chen J, Yang Z, ..., Navarro P, Shen X
medRxiv - (-) - [2023-02-14; online 2023-02-14]
Loss of Y is associated with multi-omic changes in immune cells from Alzheimer’s disease patients
Jąkalski M, Rychlicka-Buniowska E, Davies H, ..., Dumanski JP, Mieczkowski J
- - (-) - [2023-02-08; online 2023-02-08]
scAEGAN: Unification of single-cell genomics data by adversarial learning of latent space correspondences.
Khan SA, Lehmann R, Martinez-de-Morentin X, ..., Gomez-Cabrero D, Tegner J
PLoS ONE 18 (2) e0281315 [2023-02-03; online 2023-02-03]
Loci for insulin processing and secretion provide insight into type 2 diabetes risk.
Broadaway KA, Yin X, Williamson A, ..., Wheeler E, Mohlke KL
Am. J. Hum. Genet. 110 (2) 284-299 [2023-02-02; online 2023-01-23]
Data-driven neuropathological staging and subtyping of TDP-43 proteinopathies.
Young AL, Vogel JW, Robinson JL, ..., Lee EB, Hansson O
medRxiv - (-) - [2023-02-02; online 2023-02-02]
T cell receptor gene repertoire profiles in subgroups of patients with chronic lymphocytic leukemia bearing distinct genomic aberrations.
Vlachonikola E, Pechlivanis N, Karakatsoulis G, ..., Stamatopoulos K, Chatzidimitriou A
Front Oncol 13 (-) 1097942 [2023-02-01; online 2023-02-01]
Long-term SARS-CoV-2 surveillance in the wastewater of Stockholm: What lessons can be learned from the Swedish perspective?
Perez-Zabaleta M, Archer A, Khatami K, ..., Williams C, Cetecioglu Z
Sci. Total Environ. 858 (Pt 3) 160023 [2023-02-01; online 2022-11-08]
Sensing of protein and DNA complexes using solid-state nanopores
Jain S, Birgersson M, Kipen J, ..., Williams C, Herland A
Biophysical Journal 122 (3) 289a [2023-02-00; online 2023-02-00]
PIP2 binding at the voltage sensor domain facilitates KCNQ1 VSD activation and gating
Pipatpolkai T, Mitrovic D, Cui J, Delemotte L
Biophysical Journal 122 (3) 29a [2023-02-00; online 2023-02-00]
Genome sequencing is a sensitive first-line test to diagnose individuals with intellectual disability
Lindstrand A, Ek M, Kvarnung M, ..., Pettersson M, Nordgren A
Pathology 55 (-) S19-S20 [2023-02-00; online 2023-02-00]
Dissecting the mechanisms of environment sensitivity of smart probes for quantitative assessment of membrane properties
Ragaller F, Andronico L, Sykora J, ..., Vattulainen I, Sezgin E
Biophysical Journal 122 (3) 224a [2023-02-00; online 2023-02-00]
Delineating Plasmodium liver infection across space and time.
Hildebrandt F, Ankarklev J, Matuschewski K
Trends Parasitol. 39 (2) 80-82 [2023-02-00; online 2022-12-24]
Author Correction: The repertoire of mutational signatures in human cancer.
Alexandrov LB, Kim J, Haradhvala NJ, ..., Stratton MR, PCAWG Consortium
Nature 614 (7948) E41 [2023-02-00; online 2023-01-26]
Author Correction: The evolutionary history of 2,658 cancers.
Gerstung M, Jolly C, Leshchiner I, ..., Van Loo P, PCAWG Consortium
Nature 614 (7948) E42 [2023-02-00; online 2023-01-26]
Author Correction: Patterns of somatic structural variation in human cancer genomes.
Li Y, Roberts ND, Wala JA, ..., Campbell PJ, PCAWG Consortium
Nature 614 (7948) E38 [2023-02-00; online 2023-01-26]
Author Correction: Pan-cancer analysis of whole genomes.
ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium
Nature 614 (7948) E39 [2023-02-00; online 2023-01-26]
Author Correction: Genomic basis for RNA alterations in cancer.
PCAWG Transcriptome Core Group , Calabrese C, Davidson NR, ..., Zhang Z, PCAWG Consortium
Nature 614 (7948) E37 [2023-02-00; online 2023-01-26]
Author Correction: Analyses of non-coding somatic drivers in 2,658 cancer whole genomes.
Rheinbay E, Nielsen MM, Abascal F, ..., Getz G, PCAWG Consortium
Nature 614 (7948) E40 [2023-02-00; online 2023-01-26]
A Prox1 enhancer represses haematopoiesis in the lymphatic vasculature.
Kazenwadel J, Venugopal P, Oszmiana A, ..., Scott HS, Harvey NL
Nature 614 (7947) 343-348 [2023-02-00; online 2023-01-25]
7-month duration of SARS-CoV-2 mucosal immunoglobulin-A responses and protection.
Marking U, Bladh O, Havervall S, ..., Klingström J, Thålin C
Lancet Infect Dis 23 (2) 150-152 [2023-02-00; online 2023-01-11]
MDC1 maintains active elongation complexes of RNA polymerase II.
Pappas G, Munk SHN, Watanabe K, ..., Galanos P, Bartek J
Cell Reports 42 (1) 111979 [2023-01-31; online 2023-01-12]
Enhanced translation expands the endo-lysosome size and promotes antigen presentation during phagocyte activation
Hipolito VEB, Diaz JA, Tandoc KV, ..., Topisirovic I, Botelho R
- - (-) - [2023-01-31; online 2023-01-31]
Enhanced translation expands the endo-lysosome size and promotes antigen presentation during phagocyte activation
Hipolito VEB, Diaz JA, Tandoc KV, ..., Topisirovic I, Botelho R
- - (-) - [2023-01-31; online 2023-01-31]
Editorial: Effects of hormonal contraceptives on the brain.
Pletzer B, Comasco E, Hidalgo-Lopez E, Lacreuse A, Derntl B
Front Endocrinol (Lausanne) 14 (-) 1129203 [2023-01-31; online 2023-01-31]
Erika Comasco SciLifeLab Fellow
Molecular quantitative trait loci
Aguet F, Alasoo K, Li YI, ..., Montgomery SB, Lappalainen T
Nat Rev Methods Primers 3 (1) - [2023-01-25; online 2023-01-25]
Metabolic stress-induced human beta-cell death is mediated by increased intracellular levels of adenosine.
Ngamjariyawat A, Cen J, Said R, ..., Idevall-Hagren O, Welsh N
Front Endocrinol (Lausanne) 14 (-) 1060675 [2023-01-25; online 2023-01-25]
Distinct COPD subtypes in former smokers revealed by gene network perturbation analysis.
Buschur KL, Riley C, Saferali A, ..., Hersh CP, Benos PV
Respir. Res. 24 (1) 30 [2023-01-25; online 2023-01-25]
n-Type Organic Electrochemical Transistors with High Transconductance and Stability
Wang Y, Zhu G, Zeglio E, ..., Inal S, Yue W
Chem Mater 35 (2) 405-415 [2023-01-24; online 2023-01-09]
The swan genome and transcriptome, it is not all black and white.
Karawita AC, Cheng Y, Chew KY, ..., Burt DW, Short KR
Genome Biol. 24 (1) 13 [2023-01-23; online 2023-01-23]
Proline catabolism is key to facilitating Candida albicans pathogenicity
Silao FGS, Jiang T, Bereczky-Veress B, ..., Peuckert C, Ljungdahl PO
- - (-) - [2023-01-18; online 2023-01-18]
Translating single-cell genomics into cell types
Tegner JN
Nat Mach Intell 5 (1) 11-12 [2023-01-12; online 2023-01-12]
A human stomach cell type transcriptome atlas
Öling S, Struck E, Thorsen M, ..., Dusart P, Butler L
- - (-) - [2023-01-11; online 2023-01-11]
Fibroblast subsets in non-small cell lung cancer: Associations with survival, mutations, and immune features.
Pellinen T, Paavolainen L, Martín-Bernabé A, ..., Micke P, Östman A
J. Natl. Cancer Inst. 115 (1) 71-82 [2023-01-10; online 2022-09-10]
A tissue centric atlas of cell type transcriptome enrichment signatures
Dusart P, Öling S, Struck E, ..., Uhlén M, Butler L
- - (-) - [2023-01-10; online 2023-01-10]
Endogenous incretin levels and risk of first incident cancer: a prospective cohort study.
Jujić A, Godina C, Belting M, ..., Jernström H, Magnusson M
Sci Rep 13 (1) 382 [2023-01-07; online 2023-01-07]
Drug repositioning for immunotherapy in breast cancer using single-cell analysis
Mohammadi E, Jin H, Zhang C, ..., Mardinoglu A, Sekhavati MH
- - (-) - [2023-01-05; online 2023-01-05]
Fibroblast Growth Factor-23 and Risk of Cardiovascular Diseases: A Mendelian Randomization Study.
Donovan K, Herrington WG, Paré G, ..., Staplin N, on behalf of the SCALLOP Consortium
Clin J Am Soc Nephrol 18 (1) 17-27 [2023-01-01; online 2023-02-01]
Dimerization of the C-type lectin-like receptor CD93 promotes its binding to Multimerin-2 in endothelial cells.
Barbera S, Raucci L, Tassone G, ..., Pozzi C, Orlandini M
Int J Biol Macromol 224 (-) 453-464 [2023-01-01; online 2022-10-18]
Unravelling the landscape of skin cancer through single-cell transcriptomics.
Srivastava A, Bencomo T, Das I, Lee CS
Transl Oncol 27 (-) 101557 [2023-01-00; online 2022-10-17]
Temporally and spatially regulated collagen XVIII isoforms are involved in ureteric tree development via the TSP1-like domain.
Rinta-Jaskari MM, Naillat F, Ruotsalainen HJ, ..., Vainio SJ, Pihlajaniemi TA
Matrix Biol. 115 (-) 139-159 [2023-01-00; online 2023-01-06]
PatchDropout: Economizing Vision Transformers Using Patch Dropout
Liu Y, Matsoukas C, Strand F, Azizpour H, Smith K
- - (-) 3942-3951 [2023-01-00; online 2023-01-00]
Bioorthogonal azido-S1P works as substrate for S1PR1.
Sternstein C, Schlegel J, Sauer M, Seibel J
J. Lipid Res. 64 (1) 100311 [2023-01-00; online 2022-11-10]
The Role of Willpower in Major Depressive Disorder: An fMRI Study
Yulug B, Uygur B, Sayman D, ..., Velioglu HA, Mardinoglu A
- - (-) - [2023-00-00; online 2023-00-00]
The MHC-E Peptide Ligand of Checkpoint NKG2A Is Governed by Inflammatory Signals and High Turnover
Middelburg J, Ghaffari S, Schoufour TAW, ..., Weidanz J, van Hall T
- - (-) - [2023-00-00; online 2023-00-00]
Impaired Immuno-Metabolic Homeostasis and Microenvironmental Influence on Neuropsychiatric Risk in Treated HIV Infection
Mikaeloff F, Gelpi M, Escós A, ..., Nielsen SD, Neogi U
- - (-) - [2023-00-00; online 2023-00-00]
Genome-Wide Annotation of the Human Protein-Coding Genes Using Co-Expression Clustering
Bueno Álvez M, Karlsson M, Shi M, ..., Fagerberg L, Lindskog C
- - (-) - [2023-00-00; online 2023-00-00]
Distinct HLA Associations with Autoantibody-Defined Subgroups in Idiopathic Inflammatory Myopathies
Leclair V, Galindo-Feria AS, Rothwell S, ..., Lundberg IE, Diaz-Gallo LM
- - (-) - [2023-00-00; online 2023-00-00]
Ckap4 is Identified as a Therapeutic Target for the Treatment of Kidney Fibrosis
Shi M, Xu P, Kim W, ..., Mardinoglu A, Zhang C
- - (-) - [2023-00-00; online 2023-00-00]
Cell Segmentation of in situ Transcriptomics Data Using Signed Graph Partitioning
Andersson A, Behanova A, Wählby C, Malmberg F
- - (-) 139-148 [2023-00-00; online 2023-08-24]
Basic Concepts and Emergent Disease Mechanisms of Amyotrophic Lateral Sclerosis
Sirozh O, Saez-Mas A, Lafarga V, Fernandez-Capetillo O
- - (-) 644-665 [2023-00-00; online 2023-00-00]

Publications 9.5.1