Publications 2016

860 publications

Author response: The Chd1 chromatin remodeler shifts hexasomes unidirectionally
Levendosky RF, Sabantsev A, Deindl S, Bowman GD
- - (-) - [2016-12-28; online 2016-12-28]
TGF-β Affects the Differentiation of Human GM-CSF
Éliás S, Schmidt A, Kannan V, Andersson J, Tegnér J
Front Immunol 7 (-) 603 [2016-12-23; online 2016-12-23]
Affiliated researcher
Whole genome resequencing of a laboratory-adapted Drosophila melanogaster
Gilks WP, Pennell TM, Flis I, Webster MT, Morrow EH
F1000Res 5 (-) 2644 [2016-12-20; online 2016-12-20]
Production of individualized V gene databases reveals high levels of immunoglobulin genetic diversity.
Corcoran MM, Phad GE, Vázquez Bernat , ..., Martin M, Karlsson Hedestam GB
Nat Commun 7 (-) 13642 [2016-12-20; online 2016-12-20]
Affiliated researcher
Transposon Mutagenesis Reveals Fludarabine Resistance Mechanisms in Chronic Lymphocytic Leukemia.
Pandzic T, Larsson J, He L, ..., Sjöblom T, Hellström M
Clin. Cancer Res. 22 (24) 6217-6227 [2016-12-15; online 2016-03-08]
Affiliated researcher
FANCM c.5101C>T mutation associates with breast cancer survival and treatment outcome.
Kiiski JI, Fagerholm R, Tervasmäki A, ..., Blomqvist C, Nevanlinna H
Int. J. Cancer 139 (12) 2760-2770 [2016-12-15; online 2016-09-19]
Affiliated researcher
The protein phosphatase 2A regulatory subunit PR70 is a gonosomal melanoma tumor suppressor gene.
van Kempen LC, Redpath M, Elchebly M, ..., Feunteun J, Spatz A
Sci Transl Med 8 (369) 369ra177 [2016-12-14; online 2016-12-16]
Affiliated researcher
The In Vitro Stability of Circulating Tumour DNA.
Henao Diaz E, Yachnin J, Grönberg H, Lindberg J
PLoS ONE 11 (12) e0168153 [2016-12-13; online 2016-12-13]
Affiliated researcher
Serum Autoantibody Profiling of Patients with Paraneoplastic and Non-Paraneoplastic Autoimmune Retinopathy.
Ten Berge JC, van Rosmalen J, Vermeer J, ..., Rothova A, Schreurs MW
PLoS ONE 11 (12) e0167909 [2016-12-08; online 2016-12-08]
Affiliated researcher
PDGFB, a new candidate plasma biomarker for venous thromboembolism: results from the VEREMA affinity proteomics study.
Bruzelius M, Iglesias MJ, Hong MG, ..., Trégouët DA, Odeberg J
Blood 128 (23) e59-e66 [2016-12-08; online 2016-10-14]
Affiliated researcher
Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma.
Mansouri L, Noerenberg D, Young E, ..., Rosenquist R, Damm F
Blood 128 (23) 2666-2670 [2016-12-08; online 2016-09-26]
Affiliated researcher
Membrane Anchoring and Ion-Entry Dynamics in P-type ATPase Copper Transport.
Grønberg C, Sitsel O, Lindahl E, Gourdon P, Andersson M
Biophys. J. 111 (11) 2417-2429 [2016-12-06; online 2016-12-08]
Affiliated researcher
BLISS: quantitative and versatile genome-wide profiling of DNA breaks in situ
Yan WX, Mirzazadeh R, Garnerone S, ..., Bienko M, Crosetto N
- - (-) - [2016-12-04; online 2016-12-04]
The Heterogeneous Fusion Gene Landscape in Pediatric Acute Lymphoblastic Leukemia
Marincevic-Zuniga Y, Dahlberg J, Nilsson S, ..., Nordlund J, Syvänen AC
Blood 128 (22) 4081-4081 [2016-12-02; online 2016-12-02]
The Effect of Moment of Inertia on the Liquids in Centrifugal Microfluidics.
Pishbin E, Eghbal M, Fakhari S, Kazemzadeh A, Navidbakhsh M
Micromachines (Basel) 7 (12) - [2016-12-02; online 2016-12-02]
Affiliated researcher
Tailored Approaches for Refined Prognostication in Chronic Lymphocytic Leukemia Patients with Mutated Versus Unmutated Immunoglobulin Receptors
Baliakas P, Moysiadis T, Hadzidimitriou A, ..., Rosenquist R, Stamatopoulos, on behalf of ERIC K
Blood 128 (22) 3199-3199 [2016-12-02; online 2016-12-02]
Reappraising Immunoglobulin Repertoire Restrictions in Chronic Lymphocytic Leukemia: Focus on Major Stereotyped Subsets and Closely Related Satellites
Agathangelidis A, Hadzidimitriou A, Minga E, ..., Ghia P, Stamatopoulos K
Blood 128 (22) 4376-4376 [2016-12-02; online 2016-12-02]
From the Past to the Present: Wolf Phylogeography and Demographic History Based on the Mitochondrial Control Region
Ersmark E, Klütsch CFC, Chan YL, ..., Dalén L, Savolainen P
Front. Ecol. Evol. 4 (-) - [2016-12-02; online 2016-12-02]
The topogenic function of S4 promotes membrane insertion of the voltage-sensor domain in the KvAP channel.
Mishima E, Sato Y, Nanatani K, ..., Sakaguchi M, Uozumi N
Biochem. J. 473 (23) 4361-4372 [2016-12-01; online 2016-09-30]
Affiliated researcher
Validation and development of MTH1 inhibitors for treatment of cancer.
Warpman Berglund U, Sanjiv K, Gad H, ..., Scobie M, Helleday T
Ann. Oncol. 27 (12) 2275-2283 [2016-12-00; online 2016-11-08]
Affiliated researcher
The disappearing San of southeastern Africa and their genetic affinities.
Schlebusch CM, Prins F, Lombard M, Jakobsson M, Soodyall H
Hum. Genet. 135 (12) 1365-1373 [2016-12-00; online 2016-09-20]
Affiliated researcher
Structural and conformational determinants of macrocycle cell permeability.
Over B, Matsson P, Tyrchan C, ..., Duvall JR, Kihlberg J
Nat. Chem. Biol. 12 (12) 1065-1074 [2016-12-00; online 2016-10-17]
Affiliated researcher
Squalene-hopene cyclases-evolution, dynamics and catalytic scope.
Syrén PO, Henche S, Eichler A, Nestl BM, Hauer B
Curr. Opin. Struct. Biol. 41 (-) 73-82 [2016-12-00; online 2016-06-20]
Affiliated researcher
Novel genetic loci underlying human intracranial volume identified through genome-wide association.
Adams HH, Hibar DP, Chouraki V, ..., Ikram MA, Thompson PM
Nat. Neurosci. 19 (12) 1569-1582 [2016-12-00; online 2016-10-03]
Affiliated researcher
Heparanase Promotes Glioma Progression and Is Inversely Correlated with Patient Survival.
Kundu S, Xiong A, Spyrou A, ..., Li JP, Forsberg-Nilsson K
Mol. Cancer Res. 14 (12) 1243-1253 [2016-12-00; online 2016-08-26]
Affiliated researcher
Genome-wide analysis identifies 12 loci influencing human reproductive behavior.
Barban N, Jansen R, de Vlaming R, ..., Snieder H, Mills MC
Nat. Genet. 48 (12) 1462-1472 [2016-12-00; online 2016-10-31]
Affiliated researcher
Extended exome sequencing identifies BACH2 as a novel major risk locus for Addison's disease.
Eriksson D, Bianchi M, Landegren N, ..., Kämpe O, Pielberg GR
J. Intern. Med. 280 (6) 595-608 [2016-12-00; online 2016-11-02]
Affiliated researcher
Exploring the oviductal fluid proteome by a lectin-based affinity approach.
Yu H, Reiser J, Besenfelder U, ..., Artemenko K, Mayrhofer C
Proteomics 16 (23) 2962-2966 [2016-12-00; online 2016-11-09]
Affiliated researcher
Early Perspective.
Seashore-Ludlow B, Lundbäck T
J Biomol Screen 21 (10) 1019-1033 [2016-12-00; online 2016-07-20]
Affiliated researcher
Distribution and expression of microbial rhodopsins in the Baltic Sea and adjacent waters.
Brindefalk B, Ekman M, Ininbergs K, ..., Pinhassi J, Bergman B
Environ. Microbiol. 18 (12) 4442-4455 [2016-12-00; online 2016-07-14]
Affiliated researcher
Base sequence specificity of counterion binding to DNA: what can MD simulations tell us?
Atzori A, Liggi S, Laaksonen A, ..., Saba G, Mocci F
Can. J. Chem. 94 (12) 1181-1188 [2016-12-00; online 2016-12-00]
Affiliated researcher
Consistency in drug response profiling.
Mpindi JP, Yadav B, Östling P, ..., Kallioniemi O, Aittokallio T
Nature 540 (7631) E5-E6 [2016-11-30; online 2016-12-03]
DNA methylation patterns associated with oxidative stress in an ageing population.
Hedman ÅK, Zilmer M, Sundström J, Lind L, Ingelsson E
BMC Med Genomics 9 (1) 72 [2016-11-25; online 2016-11-25]
Affiliated researcher
The endosomal transcriptional regulator RNF11 integrates degradation and transport of EGFR.
Scharaw S, Iskar M, Ori A, ..., Bork P, Pepperkok R
J. Cell Biol. 215 (4) 543-558 [2016-11-21; online 2016-11-08]
Affiliated researcher
An automated approach to prepare tissue-derived spatially barcoded RNA-sequencing libraries.
Jemt A, Salmén F, Lundmark A, ..., Yucel-Lindberg T, Lundeberg J
Sci Rep 6 (-) 37137 [2016-11-16; online 2016-11-16]
Affiliated researcher
Periostin is identified as a putative metastatic marker in breast cancer-derived exosomes.
Vardaki I, Ceder S, Rutishauser D, ..., Foukakis T, Panaretakis T
Oncotarget 7 (46) 74966-74978 [2016-11-15; online 2016-09-03]
Affiliated researcher
Targeted high-throughput sequencing of candidate genes for chronic obstructive pulmonary disease.
Matsson H, Söderhäll C, Einarsdottir E, ..., Lundbäck B, Klar J
BMC Pulm Med 16 (1) 146 [2016-11-11; online 2016-11-11]
Affiliated researcher
Probabilistic inference of lateral gene transfer events.
Khan MA, Mahmudi O, Ullah I, Arvestad L, Lagergren J
BMC Bioinformatics 17 (Suppl 14) 431 [2016-11-11; online 2016-11-11]
Affiliated researcher
The stem osteichthyan Andreolepis and the origin of tooth replacement.
Chen D, Blom H, Sanchez S, Tafforeau P, Ahlberg PE
Nature 539 (7628) 237-241 [2016-11-10; online 2016-10-17]
Affiliated researcher
Cohort profile: the Finnish Genetics of Pre-eclampsia Consortium (FINNPEC).
Jääskeläinen T, Heinonen S, Kajantie E, ..., Laivuori H, FINNPEC Study Group
BMJ Open 6 (11) e013148 [2016-11-10; online 2016-11-10]
Affiliated researcher
Immunohistochemical Typing of Adenocarcinomas of the Pancreatobiliary System Improves Diagnosis and Prognostic Stratification.
Fernández Moro C, Fernandez-Woodbridge A, Alistair D'souza M, ..., Verbeke C, Bozóky B
PLoS ONE 11 (11) e0166067 [2016-11-09; online 2016-11-09]
Affiliated researcher
Case-specific potentiation of glioblastoma drugs by pterostilbene.
Schmidt L, Baskaran S, Johansson P, ..., Krona C, Nelander S
Oncotarget 7 (45) 73200-73215 [2016-11-08; online 2016-10-01]
Affiliated researcher
Whole genome resequencing of a laboratory-adapted Drosophila melanogaster population sample.
Gilks WP, Pennell TM, Flis I, Webster MT, Morrow EH
F1000Res 5 (-) 2644 [2016-11-07; online 2016-11-07]
Whole genome resequencing of a laboratory-adapted Drosophila melanogaster population sample
Gilks WP, Pennell TM, Flis I, Webster MT, Morrow EH
F1000Res 5 (-) 2644 [2016-11-07; online 2016-11-07]
Looking for Missing Proteins in the Proteome of Human Spermatozoa: An Update.
Vandenbrouck Y, Lane L, Carapito C, ..., Garin J, Pineau C
J. Proteome Res. 15 (11) 3998-4019 [2016-11-04; online 2016-08-23]
Affiliated researcher
Clonal B-cell lymphocytosis of marginal zone origin.
Xochelli A, Oscier D, Stamatopoulos K
Best Pract Res Clin Haematol 30 (1-2) 77-83 [2016-11-04; online 2016-11-04]
Affiliated researcher
Maps of context-dependent putative regulatory regions and genomic signal interactions.
Diamanti K, Umer HM, Kruczyk M, ..., Wadelius C, Komorowski J
Nucleic Acids Res. 44 (19) 9110-9120 [2016-11-02; online 2016-09-12]
Affiliated researcher
The H3 chaperone function of NASP is conserved in Arabidopsis.
Maksimov V, Nakamura M, Wildhaber T, ..., Bergquist J, Hennig L
Plant J. 88 (3) 425-436 [2016-11-00; online 2016-09-15]
Affiliated researcher
Synaptic proteins predict cognitive decline in Alzheimer's disease and Lewy body dementia.
Bereczki E, Francis PT, Howlett D, ..., Ballard C, Aarsland D
Alzheimers Dement 12 (11) 1149-1158 [2016-11-00; online 2016-05-22]
Affiliated researcher
Screening out irrelevant cell-based models of disease.
Horvath P, Aulner N, Bickle M, ..., von Schantz C, Carragher NO
Nat Rev Drug Discov 15 (11) 751-769 [2016-11-00; online 2016-09-12]
Affiliated researcher
Relating fitness to long-term environmental variations in natura.
Milesi P, Lenormand T, Lagneau C, Weill M, Labbé P
Mol. Ecol. 25 (21) 5483-5499 [2016-11-00; online 2016-10-14]
Pascal Milesi SciLifeLab Fellow
Migratory activation of parasitized dendritic cells by the protozoan Toxoplasma gondii 14-3-3 protein.
Weidner JM, Kanatani S, Uchtenhagen H, ..., Achour A, Barragan A
Cell. Microbiol. 18 (11) 1537-1550 [2016-11-00; online 2016-05-06]
Affiliated researcher
Methane oxidation at the water‐ice interface of an ice‐covered lake
Ricão Canelhas M, Denfeld BA, Weyhenmeyer GA, Bastviken D, Bertilsson S
Limnol. Oceanogr. 61 (S1) S78-S90 [2016-11-00; online 2016-03-29]
Affiliated researcher
MID-PREGNANCY CORTICOTROPIN-RELEASING HORMONE LEVELS IN ASSOCIATION WITH POSTPARTUM DEPRESSIVE SYMPTOMS.
Iliadis SI, Sylvén S, Hellgren C, ..., Sundström Poromaa I, Skalkidou A
Depress Anxiety 33 (11) 1023-1030 [2016-11-00; online 2016-05-27]
Erika Comasco SciLifeLab Fellow
Long-term outcome in young women with breast cancer: a population-based study.
Fredholm H, Magnusson K, Lindström LS, ..., Frisell J, Fredriksson I
Breast Cancer Res. Treat. 160 (1) 131-143 [2016-11-00; online 2016-09-13]
Affiliated researcher
Inferring Past Effective Population Size from Distributions of Coalescent Times.
Gattepaille L, Günther T, Jakobsson M
Genetics 204 (3) 1191-1206 [2016-11-00; online 2016-09-16]
Affiliated researcher
High migration rates shape the postglacial history of amphi-Atlantic bryophytes.
Désamoré A, Patiño J, Mardulyn P, ..., Laenen B, Vanderpoorten A
Mol. Ecol. 25 (21) 5568-5584 [2016-11-00; online 2016-10-17]
Affiliated researcher
Genomic disruption of the histone methyltransferase SETD2 in chronic lymphocytic leukaemia.
Parker H, Rose-Zerilli MJ, Larrayoz M, ..., Oscier DG, Strefford JC
Leukemia 30 (11) 2179-2186 [2016-11-00; online 2016-05-20]
Affiliated researcher
Genome-wide repression of eRNA and target gene loci by the ETV6-RUNX1 fusion in acute leukemia.
Teppo S, Laukkanen S, Liuksiala T, ..., Heinäniemi M, Lohi O
Genome Res. 26 (11) 1468-1477 [2016-11-00; online 2016-09-12]
Affiliated researcher
Diet adaptation in dog reflects spread of prehistoric agriculture.
Arendt M, Cairns KM, Ballard JW, Savolainen P, Axelsson E
Heredity (Edinb) 117 (5) 301-306 [2016-11-00; online 2016-07-13]
Affiliated researcher
Amy2B copy number variation reveals starch diet adaptations in ancient European dogs.
Ollivier M, Tresset A, Bastian F, ..., Hitte C, Hänni C
R Soc Open Sci 3 (11) 160449 [2016-11-00; online 2016-11-09]
Affiliated researcher
Rawcopy: Improved copy number analysis with Affymetrix arrays.
Mayrhofer M, Viklund B, Isaksson A
Sci Rep 6 (-) 36158 [2016-10-31; online 2016-10-31]
Affiliated researcher
Evaluation of Biocompatibility and Release of Reactive Oxygen Species of Aluminum Oxide-Coated Materials.
Mestres G, Espanol M, Xia W, Tenje M, Ott M
ACS Omega 1 (4) 706-713 [2016-10-31; online 2016-10-27]
Thermodynamics of Nanobody Binding to Lactose Permease.
Hariharan P, Andersson M, Jiang X, ..., Kaback HR, Guan L
Biochemistry 55 (42) 5917-5926 [2016-10-25; online 2016-10-12]
Affiliated researcher
Gene-specific correlation of RNA and protein levels in human cells and tissues.
Edfors F, Danielsson F, Hallström BM, ..., Forsström B, Uhlén M
Mol Syst Biol 12 (10) 883 [2016-10-20; online 2016-10-20]
Affiliated researcher
SweGen: A whole-genome map of genetic variability in a cross-section of the Swedish population
Ameur A, Dahlberg J, Olason P, ..., Magnusson P, Gyllensten U
- - (-) - [2016-10-17; online 2016-10-17]
FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma.
Suryo Rahmanto A, Savov V, Brunner A, ..., Swartling FJ, Sangfelt O
EMBO J. 35 (20) 2192-2212 [2016-10-17; online 2016-09-13]
Affiliated researcher
Binding of Pollutants to Biomolecules: A Simulation Study.
Yildirim A, Zhang J, Manzetti S, van der Spoel D
Chem. Res. Toxicol. 29 (10) 1679-1688 [2016-10-17; online 2016-09-13]
Affiliated researcher
Reconstructing a hydrogen-driven microbial metabolic network in Opalinus Clay rock.
Bagnoud A, Chourey K, Hettich RL, ..., Schwyn B, Bernier-Latmani R
Nat Commun 7 (-) 12770 [2016-10-14; online 2016-10-14]
Affiliated researcher
Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.
Segerstolpe Å, Palasantza A, Eliasson P, ..., Ämmälä C, Sandberg R
Cell Metab. 24 (4) 593-607 [2016-10-11; online 2016-09-22]
Affiliated researcher
Hydrophobic Clusters Raise the Threshold Hydrophilicity for Insertion of Transmembrane Sequences in Vivo.
Stone TA, Schiller N, Workewych N, von Heijne G, Deber CM
Biochemistry 55 (40) 5772-5779 [2016-10-11; online 2016-09-29]
Affiliated researcher
Arming the Neighborhood.
Koskiniemi S, Elf J
Dev. Cell 39 (1) 5-6 [2016-10-10; online 2016-10-12]
The Chd1 chromatin remodeler shifts hexasomes unidirectionally
Levendosky RF, Sabantsev A, Deindl S, Bowman GD
- - (-) - [2016-10-09; online 2016-10-09]
Multidimensional Normalization to Minimize Plate Effects of Suspension Bead Array Data.
Hong MG, Lee W, Nilsson P, Pawitan Y, Schwenk JM
J. Proteome Res. 15 (10) 3473-3480 [2016-10-07; online 2016-09-12]
Affiliated researcher
Accurate contact predictions for thousands of protein families using PconsC3
Skwark MJ, Michel M, Menéndez Hurtado D, Ekeberg M, Elofsson A
- - (-) - [2016-10-07; online 2016-10-07]
Molecular Diversity of Midbrain Development in Mouse, Human, and Stem Cells.
La Manno G, Gyllborg D, Codeluppi S, ..., Arenas E, Linnarsson S
Cell 167 (2) 566-580.e19 [2016-10-06; online 2016-10-08]
Affiliated researcher
ProQ3: Improved model quality assessments using Rosetta energy terms.
Uziela K, Shu N, Wallner B, Elofsson A
Sci Rep 6 (-) 33509 [2016-10-04; online 2016-10-04]
Affiliated researcher
The human PRD-like homeobox gene LEUTX has a central role in embryo genome activation.
Jouhilahti EM, Madissoon E, Vesterlund L, ..., Katayama S, Kere J
Development 143 (19) 3459-3469 [2016-10-01; online 2016-08-30]
Affiliated researcher
Whole-Exome Sequencing Suggests LAMB3 as a Susceptibility Gene for Morbid Obesity.
Jiao H, Kulyté A, Näslund E, ..., Arner P, Dahlman I
Diabetes 65 (10) 2980-2989 [2016-10-00; online 2016-07-18]
Affiliated researcher
Soluble CD93 Is Involved in Metabolic Dysregulation but Does Not Influence Carotid Intima-Media Thickness.
Strawbridge RJ, Hilding A, Silveira A, ..., Bäcklund A, IMPROVE Study Group
Diabetes 65 (10) 2888-2899 [2016-10-00; online 2016-09-24]
Affiliated researcher
Sodium pump organization in dendritic spines.
Blom H, Bernhem K, Brismar H
Neurophotonics 3 (4) 041803 [2016-10-00; online 2016-05-04]
Sibship and risk of asthma in a total population: A disease comparative approach.
Almqvist C, Olsson H, Fall T, Lundholm C
J. Allergy Clin. Immunol. 138 (4) 1219-1222.e3 [2016-10-00; online 2016-06-17]
Mutations in HECW2 are associated with intellectual disability and epilepsy.
Halvardson J, Zhao JJ, Zaghlool A, ..., Thuresson AC, Feuk L
J. Med. Genet. 53 (10) 697-704 [2016-10-00; online 2016-06-22]
Affiliated researcher
Metabolomic Quality Assessment of EDTA Plasma and Serum Samples.
Malm L, Tybring G, Moritz T, Landin B, Galli J
Biopreserv Biobank 14 (5) 416-423 [2016-10-00; online 2016-06-27]
Affiliated researcher
Integrative Modeling Reveals Annexin A2-mediated Epigenetic Control of Mesenchymal Glioblastoma.
Kling T, Ferrarese R, Ó hAilín D, ..., Carro MS, Nelander S
EBioMedicine 12 (-) 72-85 [2016-10-00; online 2016-09-18]
Functional Metabolomics Describes the Yeast Biosynthetic Regulome
Mülleder M, Calvani E, Alam MT, ..., Zelezniak A, Ralser M
Cell 167 (2) 553-565.e12 [2016-10-00; online 2016-10-00]
Aleksej Zelezniak SciLifeLab Fellow
Elevated Basal Insulin Secretion in Type 2 Diabetes Caused by Reduced Plasma Membrane Cholesterol.
Nagaraj V, Kazim AS, Helgeson J, ..., Zhang E, Renström E
Mol. Endocrinol. 30 (10) 1059-1069 [2016-10-00; online 2016-08-17]
Affiliated researcher
Effects of multiple dimensions of bacterial diversity on functioning, stability and multifunctionality.
Roger F, Bertilsson S, Langenheder S, Osman OA, Gamfeldt L
Ecology 97 (10) 2716-2728 [2016-10-00; online 2016-09-15]
Affiliated researcher
Effects of Long-Term Storage Time and Original Sampling Month on Biobank Plasma Protein Concentrations.
Enroth S, Hallmans G, Grankvist K, Gyllensten U
EBioMedicine 12 (-) 309-314 [2016-10-00; online 2016-08-26]
DNA methylome analysis of acute lymphoblastic leukemia cells reveals stochastic de novo DNA methylation in CpG islands.
Wahlberg P, Lundmark A, Nordlund J, ..., Lönnerholm G, Syvänen AC
Epigenomics 8 (10) 1367-1387 [2016-10-00; online 2016-08-23]
Affiliated researcher
Cost-effectiveness of pharmacogenetic-guided dosing of warfarin in the United Kingdom and Sweden.
Verhoef TI, Redekop WK, Langenskiold S, ..., Hughes DA, Pirmohamed M
Pharmacogenomics J. 16 (5) 478-484 [2016-10-00; online 2016-06-07]
Affiliated researcher
Biophysics in drug discovery: impact, challenges and opportunities.
Renaud JP, Chung CW, Danielson UH, ..., Hubbard RE, Nar H
Nat Rev Drug Discov 15 (10) 679-698 [2016-10-00; online 2016-08-12]
Affiliated researcher
Autoantibodies Targeting a Collecting Duct-Specific Water Channel in Tubulointerstitial Nephritis.
Landegren N, Pourmousa Lindberg M, Skov J, ..., Fenton RA, Kämpe O
J. Am. Soc. Nephrol. 27 (10) 3220-3228 [2016-10-00; online 2016-03-16]
Affiliated researcher
An introduction to plant phylogenomics with a focus on palms
Barrett CF, Bacon CD, Antonelli A, Cano Á, Hofmann T
Bot. J. Linn. Soc. 182 (2) 234-255 [2016-10-00; online 2016-03-18]
DDLS Fellow Tobias Andermann
A proposal for validation of antibodies.
Uhlen M, Bandrowski A, Carr S, ..., Snyder M, Yamamoto T
Nat. Methods 13 (10) 823-827 [2016-10-00; online 2016-09-05]
Affiliated researcher
Analysis of Body-wide Unfractionated Tissue Data to Identify a Core Human Endothelial Transcriptome.
Butler LM, Hallström BM, Fagerberg L, ..., Renné T, Odeberg J
Cell Systems 3 (3) 287-301.e3 [2016-09-28; online 2016-09-15]
Affiliated researcher
Exploration of high-density protein microarrays for antibody validation and autoimmunity profiling.
Sjöberg R, Mattsson C, Andersson E, ..., Ayoglu B, Nilsson P
N Biotechnol 33 (5 Pt A) 582-592 [2016-09-25; online 2015-09-28]
Affiliated researcher
RNA-binding motif protein 47 inhibits Nrf2 activity to suppress tumor growth in lung adenocarcinoma.
Sakurai T, Isogaya K, Sakai S, ..., Miyazono K, Koinuma D
Oncogene 35 (38) 5000-5009 [2016-09-22; online 2016-02-29]
Affiliated researcher
Functional and Structural Consequences of Nine
de Paula Michelatto D, Karlsson L, Lusa AL, ..., de Mello MP, Lajic S
Int J Endocrinol 2016 (-) 4209670 [2016-09-19; online 2016-09-19]
Affiliated researcher
XMetDB: an open access database for xenobiotic metabolism.
Spjuth O, Rydberg P, Willighagen EL, Evelo CT, Jeliazkova N
J Cheminform 8 (-) 47 [2016-09-15; online 2016-09-15]
Affiliated researcher
NUDT15 Hydrolyzes 6-Thio-DeoxyGTP to Mediate the Anticancer Efficacy of 6-Thioguanine.
Valerie NC, Hagenkort A, Page BD, ..., Jemth AS, Helleday T
Cancer Res. 76 (18) 5501-5511 [2016-09-15; online 2016-08-16]
Affiliated researcher
Life history of the stem tetrapod Acanthostega revealed by synchrotron microtomography.
Sanchez S, Tafforeau P, Clack JA, Ahlberg PE
Nature 537 (7620) 408-411 [2016-09-15; online 2016-09-07]
Affiliated researcher
Analysis with the exome array identifies multiple new independent variants in lipid loci.
Kanoni S, Masca NG, Stirrups KE, ..., Samani NJ, Deloukas P
Hum. Mol. Genet. 25 (18) 4094-4106 [2016-09-15; online 2016-07-27]
Affiliated researcher
Targeting the kinase activities of ATR and ATM exhibits antitumoral activity in mouse models of MLL-rearranged AML.
Morgado-Palacin I, Day A, Murga M, ..., Nussenzweig A, Fernandez-Capetillo O
Sci Signal 9 (445) ra91 [2016-09-13; online 2016-09-13]
Affiliated researcher
Efficacy of ATR inhibitors as single agents in Ewing sarcoma.
Nieto-Soler M, Morgado-Palacin I, Lafarga V, ..., Nussenzweig A, Fernandez-Capetillo O
Oncotarget 7 (37) 58759-58767 [2016-09-13; online 2016-09-01]
Affiliated researcher
Interplay between periodic stimulation and GABAergic inhibition in striatal network oscillations
J. Belić J, Kumar A, Hellgren Kotaleski J
- - (-) - [2016-09-06; online 2016-09-06]
A distinct mutation pattern at CTCF motifs in cancer
Umer HM, Cavalli M, Dabrowski MJ, ..., Komorowski J, Wadelius C
- - (-) - [2016-09-06; online 2016-09-06]
NDST2 (N-Deacetylase/N-Sulfotransferase-2) Enzyme Regulates Heparan Sulfate Chain Length.
Deligny A, Dierker T, Dagälv A, ..., Merry CLR, Kjellén L
J. Biol. Chem. 291 (36) 18600-18607 [2016-09-02; online 2016-07-07]
Affiliated researcher
Trans-ethnic Fine Mapping Highlights Kidney-Function Genes Linked to Salt Sensitivity.
Mahajan A, Rodan AR, Le TH, ..., Morris AP, Franceschini N
Am. J. Hum. Genet. 99 (3) 636-646 [2016-09-01; online 2016-09-03]
Affiliated researcher
POLD3 Is Haploinsufficient for DNA Replication in Mice.
Murga M, Lecona E, Kamileri I, ..., Halazonetis TD, Fernandez-Capetillo O
Mol. Cell 63 (5) 877-883 [2016-09-01; online 2016-08-11]
Affiliated researcher
Benchmarking the next generation of homology inference tools.
Saripella GV, Sonnhammer EL, Forslund K
Bioinformatics 32 (17) 2636-2641 [2016-09-01; online 2016-06-01]
Affiliated researcher
A novel variant in MYLK causes thoracic aortic dissections: genotypic and phenotypic description.
Hannuksela M, Stattin EL, Klar J, ..., Sörensen K, Carlberg B
BMC Med. Genet. 17 (1) 61 [2016-09-01; online 2016-09-01]
Affiliated researcher
Tissue microarray profiling in human heart failure.
Lal S, Nguyen L, Tezone R, ..., Li A, Dos Remedios C
Proteomics 16 (17) 2319-2326 [2016-09-00; online 2016-08-11]
Affiliated researcher
The Impact of Endurance Training on Human Skeletal Muscle Memory, Global Isoform Expression and Novel Transcripts.
Lindholm ME, Giacomello S, Werne Solnestam B, ..., Kjellqvist S, Sundberg CJ
PLoS Genet 12 (9) e1006294 [2016-09-00; online 2016-09-22]
Affiliated researcher
Strategies to improve usability and preserve accuracy in biological sequence databases.
Bengtsson-Palme J, Boulund F, Edström R, ..., Sanli K, Thorell K
Proteomics 16 (18) 2454-2460 [2016-09-00; online 2016-08-17]
DDLS Fellow Johan Bengtsson-Palme
Repeated LPS Injection Induces Distinct Changes in the Kynurenine Pathway in Mice.
Larsson MK, Faka A, Bhat M, ..., Schwieler L, Erhardt S
Neurochem. Res. 41 (9) 2243-2255 [2016-09-00; online 2016-05-10]
Affiliated researcher
Protein profiles of CCL5, HPGDS, and NPSR1 in plasma reveal association with childhood asthma.
Hamsten C, Häggmark A, Grundström J, ..., Nilsson P, van Hage M
Allergy 71 (9) 1357-1361 [2016-09-00; online 2016-05-25]
Affiliated researcher
Positron Emission Tomography to Assess the Outcome of Intraportal Islet Transplantation.
Eriksson O, Selvaraju R, Eich T, ..., Lundgren T, Korsgren O
Diabetes 65 (9) 2482-2489 [2016-09-00; online 2016-06-20]
Olof Eriksson SciLifeLab Fellow
Is low molecular weight hyaluronan an early indicator of disease in avian systemic sclerosis?
Kerje S, Hellman U, Do L, ..., Engström-Laurent A, Lindqvist U
Connect. Tissue Res. 57 (5) 337-346 [2016-09-00; online 2016-05-02]
Affiliated researcher
Conformation Traits and Gaits in the Icelandic Horse are Associated with Genetic Variants in Myostatin (MSTN).
François L, Jäderkvist Fegraeus K, Eriksson S, ..., Lindgren G, Velie BD
J. Hered. 107 (5) 431-437 [2016-09-00; online 2016-05-13]
Affiliated researcher
Clinical impact of recurrently mutated genes on lymphoma diagnostics: state-of-the-art and beyond.
Rosenquist R, Rosenwald A, Du MQ, ..., Stamatopoulos K, European Research Initiative on CLL (ERIC) and the European Association for Haematopathology (EAHP)
Haematologica 101 (9) 1002-1009 [2016-09-00; online 2016-09-02]
Affiliated researcher
Benchmarking of algorithms for 3D tissue reconstruction
Kartasalo K, Latonen L, Visakorpi T, Nykter M, Ruusuvuori P
- - (-) 2360-2364 [2016-09-00; online 2016-09-00]
DDLS Fellow Kimmo Kartasalo
Autoantibody targets in vaccine-associated narcolepsy.
Häggmark-Månberg A, Zandian A, Forsström B, ..., Olsson T, Nilsson P
Autoimmunity 49 (6) 421-433 [2016-09-00; online 2016-05-20]
Affiliated researcher
A software tool for studying the size and shape of human cardiomyocytes
Rasku J, Ojala M, Pölönen RP, ..., Aalto-Setälä K, Juhola M
Biomedical Signal Processing and Control 30 (-) 134-139 [2016-09-00; online 2016-09-00]
DDLS Fellow Kimmo Kartasalo
A Role for the Chromatin-Remodeling Factor BAZ1A in Neurodevelopment.
Zaghlool A, Halvardson J, Zhao JJ, ..., Thuresson AC, Feuk L
Hum. Mutat. 37 (9) 964-975 [2016-09-00; online 2016-07-08]
Affiliated researcher
A Rickettsiales symbiont of amoebae with ancient features.
Schulz F, Martijn J, Wascher F, ..., Ettema TJ, Horn M
Environ. Microbiol. 18 (8) 2326-2342 [2016-09-00; online 2015-06-05]
Affiliated researcher
Origin of the U87MG glioma cell line: Good news and bad news.
Allen M, Bjerke M, Edlund H, Nelander S, Westermark B
Sci Transl Med 8 (354) 354re3 [2016-08-31; online 2016-09-02]
Affiliated researcher
The Adipose Transcriptional Response to Insulin Is Determined by Obesity, Not Insulin Sensitivity.
Rydén M, Hrydziuszko O, Mileti E, ..., Daub CO, Arner P
Cell Reports 16 (9) 2317-2326 [2016-08-30; online 2016-08-18]
Affiliated researcher
High GC Content Causes De Novo Created Proteins to be Intrinsically Disordered
Basile W, Sachenkova O, Light S, Elofsson A
- - (-) - [2016-08-30; online 2016-08-30]
Cystatin C and Cardiovascular Disease: A Mendelian Randomization Study.
van der Laan SW, Fall T, Soumaré A, ..., Holmes MV, Asselbergs FW
J. Am. Coll. Cardiol. 68 (9) 934-945 [2016-08-30; online 2016-08-27]
Affiliated researcher
Fast Antibiotic Susceptibility Testing based on single cell growth rate measurements
Baltekin Ö, Boucharin A, Tano E, Andersson DI, Elf J
- - (-) - [2016-08-26; online 2016-08-26]
The Competing Mechanisms of Phosphate Monoester Dianion Hydrolysis.
Duarte F, Barrozo A, Åqvist J, Williams NH, Kamerlin SC
J. Am. Chem. Soc. 138 (33) 10664-10673 [2016-08-24; online 2016-08-15]
Affiliated researcher
Enantioselective Organocatalyzed Transformations of β-Ketoesters.
Govender T, Arvidsson PI, Maguire GE, Kruger HG, Naicker T
Chem. Rev. 116 (16) 9375-9437 [2016-08-24; online 2016-07-27]
Affiliated researcher
An RGS2 3'UTR polymorphism is associated with preeclampsia in overweight women.
Karppanen T, Kaartokallio T, Klemetti MM, ..., Staff AC, Laivuori H
BMC Genet. 17 (1) 121 [2016-08-24; online 2016-08-24]
Affiliated researcher
Visualizing the Nonhomogeneous Structure of RAD51 Filaments Using Nanofluidic Channels.
Fornander LH, Frykholm K, Fritzsche J, ..., Modesti M, Westerlund F
Langmuir 32 (33) 8403-8412 [2016-08-23; online 2016-08-12]
Affiliated researcher
Ras and TGF-β signaling enhance cancer progression by promoting the ΔNp63 transcriptional program.
Vasilaki E, Morikawa M, Koinuma D, ..., Miyazono K, Heldin CH
Sci Signal 9 (442) ra84 [2016-08-23; online 2016-08-23]
Affiliated researcher
Deep Learning and Association Rule Mining for Predicting Drug Response in Cancer. A Personalised Medicine Approach
Vougas K, Krochmal M, Jackson T, ..., Bartek J, Gorgoulis VG
- - (-) - [2016-08-19; online 2016-08-19]
In Situ Proximity Ligation Assay (In Situ PLA) to Assess PTP-Protein Interactions.
Koch S, Helbing I, Böhmer SA, ..., Söderberg O, Böhmer FD
Methods in molecular biology (Clifton, N.J.) 1447 (-) 217-242 [2016-08-16; online 2016-08-16]
Multiplex PCB-based electrochemical detection of cancer biomarkers using MLPA-barcode approach.
Sánchez JL, Henry OY, Joda H, ..., Riley I, O'Sullivan CK
Biosens Bioelectron 82 (-) 224-232 [2016-08-15; online 2016-04-07]
Affiliated researcher
Stratification of responders towards eculizumab using a structural epitope mapping strategy.
Volk AL, Hu FJ, Berglund MM, ..., Uhlen M, Rockberg J
Sci Rep 6 (-) 31365 [2016-08-11; online 2016-08-11]
Affiliated researcher
Global profiling of SRP interaction with nascent polypeptides.
Schibich D, Gloge F, Pöhner I, ..., Bukau B, Kramer G
Nature 536 (7615) 219-223 [2016-08-11; online 2016-08-03]
Affiliated researcher
Large-scale ligand-based predictive modelling using support vector machines.
Alvarsson J, Lampa S, Schaal W, ..., Wikberg JE, Spjuth O
J Cheminform 8 (-) 39 [2016-08-10; online 2016-08-10]
Affiliated researcher
Role of Conserved Gly-Gly Pairs on the Periplasmic Side of LacY.
Jiang X, Andersson M, Chau BT, ..., Villafuerte MK, Kaback HR
Biochemistry 55 (31) 4326-4332 [2016-08-09; online 2016-08-01]
Affiliated researcher
A genome-wide screening uncovers the role of CCAR2 as an antagonist of DNA end resection.
López-Saavedra A, Gómez-Cabello D, Domínguez-Sánchez MS, ..., Bartek J, Huertas P
Nat Commun 7 (-) 12364 [2016-08-09; online 2016-08-09]
Affiliated researcher
Stromal Hedgehog signalling is downregulated in colon cancer and its restoration restrains tumour growth.
Gerling M, Büller NV, Kirn LM, ..., van den Brink GR, Toftgård R
Nat Commun 7 (-) 12321 [2016-08-05; online 2016-08-05]
Affiliated researcher
Photoswitchable Spiropyran Dyads for Biological Imaging.
Xiong Y, Rivera-Fuentes P, Sezgin E, ..., Eggeling C, Anderson HL
Org. Lett. 18 (15) 3666-3669 [2016-08-05; online 2016-07-26]
Erdinc Sezgin SciLifeLab Fellow
Integration of a Droplet-Based Microfluidic System and Silicon Nanoribbon FET Sensor.
Afrasiabi R, Soderberg LM, Joensson HN, ..., Andersson Svahn H, Linnros J
Micromachines (Basel) 7 (8) - [2016-08-05; online 2016-08-05]
Affiliated researcher
The genetic architecture of type 2 diabetes.
Fuchsberger C, Flannick J, Teslovich TM, ..., Altshuler D, McCarthy MI
Nature 536 (7614) 41-47 [2016-08-04; online 2016-07-11]
Affiliated researcher
The chaperone co-inducer BGP-15 alleviates ventilation-induced diaphragm dysfunction.
Salah H, Li M, Cacciani N, ..., Salviati L, Larsson L
Sci Transl Med 8 (350) 350ra103 [2016-08-03; online 2016-08-05]
Affiliated researcher
Simulated single molecule microscopy with SMeagol.
Lindén M, Ćurić V, Boucharin A, Fange D, Elf J
Bioinformatics 32 (15) 2394-2395 [2016-08-01; online 2016-03-04]
Affiliated researcher
Profilin connects actin assembly with microtubule dynamics.
Nejedla M, Sadi S, Sulimenko V, ..., Aspenström P, Karlsson R
Mol. Biol. Cell 27 (15) 2381-2393 [2016-08-01; online 2016-06-15]
Affiliated researcher
Designing and Applying Proximity-Dependent Hybridization Chain Reaction.
Koos B, Söderberg O
Curr Protoc Protein Sci 85 (-) 19.28.1-19.28.13 [2016-08-01; online 2016-08-01]
Adaptation to different types of stress converge on mitochondrial metabolism.
Lahtvee PJ, Kumar R, Hallström BM, Nielsen J
Mol. Biol. Cell 27 (15) 2505-2514 [2016-08-01; online 2016-06-15]
Affiliated researcher
Tuning fresh: radiation through rewiring of central metabolism in streamlined bacteria.
Eiler A, Mondav R, Sinclair L, ..., Woyke T, Bertilsson S
ISME J 10 (8) 1902-1914 [2016-08-00; online 2016-01-19]
Affiliated researcher
SATB2 is expressed in Merkel cell carcinoma.
Fukuhara M, Agnarsdóttir M, Edqvist PH, Coter A, Ponten F
Arch. Dermatol. Res. 308 (6) 449-454 [2016-08-00; online 2016-06-04]
Affiliated researcher
Otopalatodigital spectrum disorders: refinement of the phenotypic and mutational spectrum.
Moutton S, Fergelot P, Naudion S, ..., Goizet C, Coupry I
J. Hum. Genet. 61 (8) 693-699 [2016-08-00; online 2016-05-19]
Affiliated researcher
Initial hyperinsulinemia and subsequent β-cell dysfunction is associated with elevated palmitate levels.
Staaf J, Ubhayasekera SJ, Sargsyan E, ..., Forslund A, Bergsten P
Pediatr. Res. 80 (2) 267-274 [2016-08-00; online 2016-04-11]
Affiliated researcher
Impact of ocean acidification on antimicrobial activity in gills of the blue mussel (Mytilus edulis).
Hernroth B, Baden S, Tassidis H, ..., Bergström Lind S, Bergquist J
Fish Shellfish Immunol. 55 (-) 452-459 [2016-08-00; online 2016-06-08]
Affiliated researcher
Evidence for genetic regulation of the human parieto-occipital 10-Hz rhythmic activity.
Salmela E, Renvall H, Kujala J, ..., Salmelin R, Kere J
Eur. J. Neurosci. 44 (3) 1963-1971 [2016-08-00; online 2016-07-04]
Affiliated researcher
Different spectra of recurrent gene mutations in subsets of chronic lymphocytic leukemia harboring stereotyped B-cell receptors.
Sutton LA, Young E, Baliakas P, ..., Rosenquist R, ERIC, the European Research Initiative on CLL
Haematologica 101 (8) 959-967 [2016-08-00; online 2016-05-19]
Affiliated researcher
Coordinated disassembly of the divisome complex in Escherichia coli.
Söderström B, Mirzadeh K, Toddo S, ..., Skoglund U, Daley DO
Mol. Microbiol. 101 (3) 425-438 [2016-08-00; online 2016-05-23]
Affiliated researcher
Acoustic micro-vortexing of fluids, particles and cells in disposable microfluidic chips.
Iranmanesh I, Ohlin M, Ramachandraiah H, ..., Russom A, Wiklund M
Biomed Microdevices 18 (4) 71 [2016-08-00; online 2016-07-23]
Affiliated researcher
A Longitudinal Follow-up of Autoimmune Polyendocrine Syndrome Type 1.
Bruserud Ø, Oftedal BE, Landegren N, ..., Wolff AB, Husebye ES
J. Clin. Endocrinol. Metab. 101 (8) 2975-2983 [2016-08-00; online 2016-06-02]
Affiliated researcher
The Synchronization of Replication and Division Cycles in Individual E. coli Cells.
Wallden M, Fange D, Lundius EG, Baltekin Ö, Elf J
Cell 166 (3) 729-739 [2016-07-28; online 2016-07-30]
Affiliated researcher
Human cytomegalovirus may promote tumour progression by upregulating arginase-2.
Costa H, Xu X, Overbeek G, ..., Söderberg-Naucler C, Yaiw KC
Oncotarget 7 (30) 47221-47231 [2016-07-26; online 2016-07-01]
Affiliated researcher
FEELnc: A tool for Long non-coding RNAs annotation and its application to the dog transcriptome
Wucher V, Legeai F, Hédan B, ..., Hitte C, Derrien T
- - (-) - [2016-07-18; online 2016-07-18]
Identification of meat products by shotgun spectral matching.
Ohana D, Dalebout H, Marissen RJ, ..., Deelder AM, Palmblad M
Food Chem 203 (-) 28-34 [2016-07-15; online 2016-02-02]
Affiliated researcher
Abstract LB-176: The human androgen receptor regulates DNA damage response (DDR) in prostate cancer
Asim M, Zecchini H, Tarish F, ..., Helleday T, Neal D
Cancer Res. 76 (14_Supplement) LB-176-LB-176 [2016-07-15; online 2016-07-15]
Abstract 3881: Breast cancer proteogenomics landscape defines subtype specific protein level regulations and reveals proteins coded by pseudogenic loci
Johansson H, Zhu Y, Haugland M, ..., Borresen-Dale AL, Lehtio J
Cancer Res. 76 (14_Supplement) 3881-3881 [2016-07-15; online 2016-07-15]
Abstract 2385: Understanding the dynamic interplay between genetically different cancer cell clones in glioblastoma
Guo M, Heller S, Thorslund J, ..., Nistér M, Hägerstrand D
Cancer Res. 76 (14_Supplement) 2385-2385 [2016-07-15; online 2016-07-15]
Abstract 1260: Polymerase kappa determines the sensitivity of MTH1 inhibitors to cisplatin-resistant cell
Sanjiv K, Gad H, Rudd S, ..., Hendrickson AW, Helleday T
Cancer Res. 76 (14_Supplement) 1260-1260 [2016-07-15; online 2016-07-15]
Abstract 1109: AAGUGC-microRNAs are an integral part of an oncogenic signaling network driving non-small cell lung cancer proliferation
Zhou Y, Frings O, Fredlund E, ..., Branca RM, Orre LM
Cancer Res. 76 (14_Supplement) 1109-1109 [2016-07-15; online 2016-07-15]
Cloche is a bHLH-PAS transcription factor that drives haemato-vascular specification.
Reischauer S, Stone OA, Villasenor A, ..., Andersson O, Stainier DY
Nature 535 (7611) 294-298 [2016-07-14; online 2016-07-15]
Affiliated researcher
Human serum-derived protein removes the need for coating in defined human pluripotent stem cell culture.
Pijuan-Galitó S, Tamm C, Schuster J, ..., Merry CL, Annerén C
Nat Commun 7 (-) 12170 [2016-07-13; online 2016-07-13]
Affiliated researcher
Mendelian randomisation analysis strongly implicates adiposity with risk of developing colorectal cancer.
Jarvis D, Mitchell JS, Law PJ, ..., Tomlinson IP, Houlston RS
Br. J. Cancer 115 (2) 266-272 [2016-07-12; online 2016-06-23]
Affiliated researcher
Directly linked hydroporphyrin dimers.
Xiong R, Arkhypchuk AI, Kovacs D, Orthaber A, Eszter Borbas K
Chem. Commun. (Camb.) 52 (58) 9056-9058 [2016-07-12; online 2016-02-10]
Ruisheng Xiong SciLifeLab Fellow
Identifying Genetic Signatures of Natural Selection Using Pooled Population Sequencing in Picea abies.
Chen J, Källman T, Ma XF, ..., Morgante M, Lascoux M
G3 6 (7) 1979-1989 [2016-07-07; online 2016-07-07]
Affiliated researcher
Exome sequencing in pooled DNA samples to identify maternal pre-eclampsia risk variants.
Kaartokallio T, Wang J, Heinonen S, ..., Kere J, Laivuori H
Sci Rep 6 (-) 29085 [2016-07-07; online 2016-07-07]
Affiliated researcher
Survival-associated heterogeneity of marker-defined perivascular cells in colorectal cancer.
Mezheyeuski A, Bradic Lindh M, Guren TK, ..., Sorbye H, Östman A
Oncotarget 7 (27) 41948-41958 [2016-07-05; online 2016-06-02]
Affiliated researcher
Estrogen receptor beta reduces colon cancer metastasis through a novel miR-205 - PROX1 mechanism.
Nguyen-Vu T, Wang J, Mesmar F, ..., Bondesson M, Williams C
Oncotarget 7 (27) 42159-42171 [2016-07-05; online 2016-06-11]
Affiliated researcher
Klinefelter's syndrome (47,XXY) is in excess among men with Sjögren's syndrome.
Harris VM, Sharma R, Cavett J, ..., Sivils KL, Scofield RH
Clin. Immunol. 168 (-) 25-29 [2016-07-00; online 2016-04-22]
Affiliated researcher
Genome-wide selective sweeps and gene-specific sweeps in natural bacterial populations.
Bendall ML, Stevens SL, Chan LK, ..., McMahon KD, Malmstrom RR
ISME J 10 (7) 1589-1601 [2016-07-00; online 2016-01-08]
Affiliated researcher
Corticolimbic anatomical characteristics predetermine risk for chronic pain.
Vachon-Presseau E, Tétreault P, Petre B, ..., Baliki MN, Apkarian AV
Brain 139 (Pt 7) 1958-1970 [2016-07-00; online 2016-05-05]
Affiliated researcher Erika Comasco SciLifeLab Fellow
Constraints on methane oxidation in ice-covered boreal lakes
Denfeld BA, Ricão Canelhas M, Weyhenmeyer GA, ..., Eiler A, Bastviken D
J. Geophys. Res. Biogeosci. 121 (7) 1924-1933 [2016-07-00; online 2016-07-22]
Affiliated researcher
Chronic kidney disease and 10-year risk of cardiovascular death.
Holzmann MJ, Carlsson AC, Hammar N, ..., Wändell P, Ärnlöv J
Eur J Prev Cardiol 23 (11) 1187-1194 [2016-07-00; online 2015-11-05]
Affiliated researcher
Antagonists of IGF:Vitronectin Interactions Inhibit IGF-I-Induced Breast Cancer Cell Functions.
Kashyap AS, Shooter GK, Shokoohmand A, ..., Upton Z, Hollier BG
Mol. Cancer Ther. 15 (7) 1602-1613 [2016-07-00; online 2016-05-09]
Affiliated researcher
Additional trisomies amongst patients with chronic lymphocytic leukemia carrying trisomy 12: the accompanying chromosome makes a difference.
Baliakas P, Puiggros A, Xochelli A, ..., Espinet B, Stamatopoulos K
Haematologica 101 (7) e299-e302 [2016-07-00; online 2016-04-21]
A draft fur seal genome provides insights into factors affecting SNP validation and how to mitigate them.
Humble E, Martinez-Barrio A, Forcada J, ..., Wolf JB, Hoffman JI
Mol Ecol Resour 16 (4) 909-921 [2016-07-00; online 2016-01-20]
Affiliated researcher
Mechanisms of TGFβ-Induced Epithelial-Mesenchymal Transition.
Moustakas A, Heldin CH
J Clin Med 5 (7) - [2016-06-29; online 2016-06-29]
Heparanase expression upregulates platelet adhesion activity and thrombogenicity.
Cui H, Tan YX, Österholm C, ..., Vlodavsky I, Li JP
Oncotarget 7 (26) 39486-39496 [2016-06-28; online 2016-10-26]
Affiliated researcher
Conformational diversity and enantioconvergence in potato epoxide hydrolase 1.
Bauer P, Carlsson ÅJ, Amrein BA, ..., Widersten M, Kamerlin SC
Org. Biomol. Chem. 14 (24) 5639-5651 [2016-06-28; online 2016-04-06]
Affiliated researcher
Genome-wide screen of cell-cycle regulators in normal and tumor cells identifies a differential response to nucleosome depletion
Sokolova M, Turunen M, Mortusewicz O, ..., Helleday T, Taipale J
- - (-) - [2016-06-23; online 2016-06-23]
Cryptosporidium as a testbed for single cell genome characterization of unicellular eukaryotes.
Troell K, Hallström B, Divne AM, ..., Beser J, Bertilsson S
BMC Genomics 17 (-) 471 [2016-06-23; online 2016-06-23]
Affiliated researcher
Genetic heterogeneity in primary and relapsed mantle cell lymphomas: Impact of recurrent CARD11 mutations.
Wu C, de Miranda NF, Chen L, ..., Sander B, Pan-Hammarström Q
Oncotarget 7 (25) 38180-38190 [2016-06-21; online 2016-10-23]
Affiliated researcher
iGEMS: an integrated model for identification of alternative exon usage events.
Sood S, Szkop KJ, Nakhuda A, ..., Larsson O, Timmons JA
Nucleic Acids Res. 44 (11) e109 [2016-06-20; online 2016-04-19]
Affiliated researcher
Identification of Cancer Related Genes Using a Comprehensive Map of Human Gene Expression.
Torrente A, Lukk M, Xue V, ..., Rung J, Brazma A
PLoS ONE 11 (6) e0157484 [2016-06-20; online 2016-06-20]
Affiliated researcher
Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2
Kimanius D, Forsberg BO, Scheres SH, Lindahl E
- - (-) - [2016-06-19; online 2016-06-19]
Effects of Fluoxetine on Human Embryo Development.
Kaihola H, Yaldir FG, Hreinsson J, ..., Åkerud H, Sundström-Poromaa I
Front. Cell. Neurosci. 10 (-) 160 [2016-06-16; online 2016-06-16]
Affiliated researcher
Read-based phasing of related individuals.
Garg S, Martin M, Marschall T
Bioinformatics 32 (12) i234-i242 [2016-06-15; online 2016-06-17]
Affiliated researcher
Protein Z: A putative novel biomarker for early detection of ovarian cancer.
Russell MR, Walker MJ, Williamson AJ, ..., Jacobs I, Graham RL
Int. J. Cancer 138 (12) 2984-2992 [2016-06-15; online 2016-02-19]
Affiliated researcher
The histone methyltransferase EZH2 as a novel prosurvival factor in clinically aggressive chronic lymphocytic leukemia.
Papakonstantinou N, Ntoufa S, Chartomatsidou E, ..., Rosenquist R, Stamatopoulos K
Oncotarget 7 (24) 35946-35959 [2016-06-14; online 2016-05-19]
Affiliated researcher
Regulation of Bone Morphogenetic Protein Signaling by ADP-ribosylation.
Watanabe Y, Papoutsoglou P, Maturi V, ..., Heldin CH, Moustakas A
J. Biol. Chem. 291 (24) 12706-12723 [2016-06-10; online 2016-04-21]
Affiliated researcher
Reciprocal voltage sensor-to-pore coupling leads to potassium channel C-type inactivation.
Conti L, Renhorn J, Gabrielsson A, ..., Lindahl E, Elinder F
Sci Rep 6 (-) 27562 [2016-06-09; online 2016-06-09]
Affiliated researcher
Reorganization of Lipid Diffusion by Myelin Basic Protein as Revealed by STED Nanoscopy.
Steshenko O, Andrade DM, Honigmann A, ..., Simons M, Eggeling C
Biophys. J. 110 (11) 2441-2450 [2016-06-07; online 2016-06-09]
Erdinc Sezgin SciLifeLab Fellow
Recommendations on e-infrastructures for next-generation sequencing.
Spjuth O, Bongcam-Rudloff E, Dahlberg J, ..., Vezzi F, Korpelainen E
Gigascience 5 (-) 26 [2016-06-07; online 2016-06-07]
Affiliated researcher
Genetic Basis for Red Coloration in Birds.
Lopes RJ, Johnson JD, Toomey MB, ..., Corbo JC, Carneiro M
Curr. Biol. 26 (11) 1427-1434 [2016-06-06; online 2016-05-19]
Affiliated researcher
A comparative evaluation of data-merging and meta-analysis methods for reconstructing gene-gene interactions.
Lagani V, Karozou AD, Gomez-Cabrero D, Silberberg G, Tsamardinos I
BMC Bioinformatics 17 Suppl 5 (-) 194 [2016-06-06; online 2016-06-06]
Affiliated researcher
Elevated levels of FN1 and CCL2 in bronchoalveolar lavage fluid from sarcoidosis patients.
Hamsten C, Wiklundh E, Grönlund H, ..., Grunewald J, Häggmark-Månberg A
Respir. Res. 17 (1) 69 [2016-06-04; online 2016-06-04]
Affiliated researcher
TT-seq maps the human transient transcriptome.
Schwalb B, Michel M, Zacher B, ..., Gagneur J, Cramer P
Science 352 (6290) 1225-1228 [2016-06-03; online 2016-06-04]
Affiliated researcher
DNA REPAIR. Drugging DNA repair.
Jackson SP, Helleday T
Science (New York, N.Y.) 352 (6290) 1178-1179 [2016-06-03; online 2016-06-04]
Prognostic impact of epigenetic classification in chronic lymphocytic leukemia: The case of subset #2.
Bhoi S, Ljungström V, Baliakas P, ..., Rosenquist R, Mansouri L
Epigenetics 11 (6) 449-455 [2016-06-02; online 2016-04-29]
Affiliated researcher
Mosaic Loss of Chromosome Y in Blood Is Associated with Alzheimer Disease.
Dumanski JP, Lambert JC, Rasi C, ..., Lind L, Forsberg LA
Am. J. Hum. Genet. 98 (6) 1208-1219 [2016-06-02; online 2016-05-23]
Affiliated researcher
Hummingbird: monitoring and analyzing flash X-ray imaging experiments in real time.
Daurer BJ, Hantke MF, Nettelblad C, Maia FR
J Appl Crystallogr 49 (Pt 3) 1042-1047 [2016-06-01; online 2016-04-18]
Identification of Multiple Loci Associated with Social Parasitism in Honeybees.
Wallberg A, Pirk CW, Allsopp MH, Webster MT
PLoS Genet 12 (6) e1006097 [2016-06-00; online 2016-06-09]
Affiliated researcher
High density of REC8 constrains sister chromatid axes and prevents illegitimate synaptonemal complex formation.
Agostinho A, Manneberg O, van Schendel R, ..., Brismar H, Höög C
EMBO Rep. 17 (6) 901-913 [2016-06-00; online 2016-05-11]
Affiliated researcher
GPR44 is a pancreatic protein restricted to the human beta cell.
Hellström-Lindahl E, Danielsson A, Ponten F, ..., Johansson L, Eriksson O
Acta Diabetol 53 (3) 413-421 [2016-06-00; online 2015-10-14]
Affiliated researcher Olof Eriksson SciLifeLab Fellow
Epigenome-wide DNA methylation patterns associated with fatigue in primary Sjögren's syndrome.
Brække Norheim K, Imgenberg-Kreuz J, Jonsdottir K, ..., Nordmark G, Omdal R
Rheumatology (Oxford) 55 (6) 1074-1082 [2016-06-00; online 2016-03-10]
Affiliated researcher
Detection of Biomarkers with Solid-Phase Proximity Ligation Assay in Patients with Colorectal Cancer.
Ghanipour L, Darmanis S, Landegren U, ..., Påhlman L, Birgisson H
Transl Oncol 9 (3) 251-255 [2016-06-00; online 2016-06-09]
Affiliated researcher
Aryl Hydrocarbon Receptor-Interacting Protein-Like 1 in Cancer-Associated Retinopathy.
Dalin F, Adamus G, Yang S, ..., Kämpe O, Alimohammadi M
Ophthalmology 123 (6) 1401-1404 [2016-06-00; online 2016-02-04]
Affinity proteomics discovers decreased levels of AMFR in plasma from Osteoporosis patients.
Qundos U, Drobin K, Mattsson C, ..., Michaëlsson K, Schwenk JM
Proteomics Clin Appl 10 (6) 681-690 [2016-06-00; online 2015-04-21]
Affiliated researcher
Variants within the SP110 nuclear body protein modify risk of canine degenerative myelopathy.
Ivansson EL, Megquier K, Kozyrev SV, ..., Coates JR, Lindblad-Toh K
Proc. Natl. Acad. Sci. U.S.A. 113 (22) E3091-E3100 [2016-05-31; online 2016-05-16]
Affiliated researcher
Genome-culture coevolution promotes rapid divergence of killer whale ecotypes.
Foote AD, Vijay N, Ávila-Arcos MC, ..., Gilbert MT, Wolf JB
Nat Commun 7 (-) 11693 [2016-05-31; online 2016-05-31]
Affiliated researcher
Principles for RNA metabolism and alternative transcription initiation within closely spaced promoters
Chen Y, Pai AA, Herudek J, ..., Heick Jensen T, Sandelin A
- - (-) - [2016-05-27; online 2016-05-27]
New technologies for DNA analysis--a review of the READNA Project.
McGinn S, Bauer D, Brefort T, ..., Willcocks JP, Gut IG
N Biotechnol 33 (3) 311-330 [2016-05-25; online 2015-10-26]
Affiliated researcher
Minimal selective concentrations of tetracycline in complex aquatic bacterial biofilms.
Lundström SV, Östman M, Bengtsson-Palme J, ..., Flach CF, Larsson DGJ
Sci. Total Environ. 553 (-) 587-595 [2016-05-15; online 2016-03-22]
DDLS Fellow Johan Bengtsson-Palme
Standardized benchmarking in the quest for orthologs.
Altenhoff AM, Boeckmann B, Capella-Gutierrez S, ..., Sonnhammer E, Dessimoz C
Nat. Methods 13 (5) 425-430 [2016-05-00; online 2016-04-04]
Affiliated researcher
Selection of optimal chelator improves the contrast of GRPR imaging using bombesin analogue RM26.
Mitran B, Varasteh Z, Selvaraju RK, ..., Rosenström U, Orlova A
Int. J. Oncol. 48 (5) 2124-2134 [2016-05-00; online 2016-03-09]
Affiliated researcher
Increased diversification rates follow shifts to bisexuality in liverworts.
Laenen B, Machac A, Gradstein SR, ..., Shaw AJ, Vanderpoorten A
New Phytol. 210 (3) 1121-1129 [2016-05-00; online 2016-02-01]
Affiliated researcher
Genome-Wide Analysis Identifies Germ-Line Risk Factors Associated with Canine Mammary Tumours.
Melin M, Rivera P, Arendt M, ..., Rönnberg H, Lindblad-Toh K
PLoS Genet 12 (5) e1006029 [2016-05-00; online 2016-05-09]
Affiliated researcher
Antigen arrays for profiling autoantibody repertoires.
Ayoglu B, Schwenk JM, Nilsson P
Bioanalysis 8 (10) 1105-1126 [2016-05-00; online 2016-04-21]
Affiliated researcher
Abstract 620: Mutations in FLT1 and COL4A1 Protect Against Early Stage Atherosclerosis in Overfed Zebrafish Larvae
den Hoed M, Conrad L, Bandaru M, ..., Larsson A, Ingelsson E
Arterioscler. Thromb. Vasc. Biol. 36 (suppl_1) - [2016-05-00; online 2016-05-00]
Staying Clear of the Dragons.
Elf J
Cell Systems 2 (4) 219-220 [2016-04-27; online 2016-04-27]
An Improved microRNA Annotation of the Canine Genome.
Penso-Dolfin L, Swofford R, Johnson J, ..., Moxon S, Di Palma F
PLoS ONE 11 (4) e0153453 [2016-04-27; online 2016-04-27]
Affiliated researcher
Elevated Levels of SOX10 in Serum from Vitiligo and Melanoma Patients, Analyzed by Proximity Ligation Assay.
Blokzijl A, Chen LE, Gustafsdottir SM, ..., Kamali-Moghaddam M, Hedstrand H
PLoS ONE 11 (4) e0154214 [2016-04-25; online 2016-04-25]
Affiliated researcher
Effects of warming on a Mediterranean phytoplankton community
Pulina S, Brutemark A, Suikkanen S, ..., Sechi N, Lugliè A
Web Ecol. 16 (1) 89-92 [2016-04-22; online 2016-04-22]
Affiliated researcher
A Genome-wide CRISPR Screen Identifies CDC25A as a Determinant of Sensitivity to ATR Inhibitors.
Ruiz S, Mayor-Ruiz C, Lafarga V, ..., Ortega S, Fernandez-Capetillo O
Mol. Cell 62 (2) 307-313 [2016-04-21; online 2016-04-07]
Affiliated researcher
Improved topology prediction using the terminal hydrophobic helices rule.
Peters C, Tsirigos KD, Shu N, Elofsson A
Bioinformatics 32 (8) 1158-1162 [2016-04-15; online 2015-12-07]
Affiliated researcher
Hypoxic Signaling and the Cellular Redox Tumor Environment Determine Sensitivity to MTH1 Inhibition.
Bräutigam L, Pudelko L, Jemth AS, ..., Stenmark P, Helleday T
Cancer Res. 76 (8) 2366-2375 [2016-04-15; online 2016-02-09]
Affiliated researcher
RING finger protein 31 promotes p53 degradation in breast cancer cells.
Zhu J, Zhao C, Zhuang T, ..., Strömblad S, Dahlman-Wright K
Oncogene 35 (15) 1955-1964 [2016-04-14; online 2015-07-06]
Affiliated researcher
Microchip Screening Platform for Single Cell Assessment of NK Cell Cytotoxicity.
Guldevall K, Brandt L, Forslund E, ..., Uhlin M, Önfelt B
Front Immunol 7 (-) 119 [2016-04-05; online 2016-04-05]
Affiliated researcher
mTORC1 and CK2 coordinate ternary and eIF4F complex assembly.
Gandin V, Masvidal L, Cargnello M, ..., Larsson O, Topisirovic I
Nat Commun 7 (-) 11127 [2016-04-04; online 2016-04-04]
Affiliated researcher
3D Bioprinting of Tissue/Organ Models.
Pati F, Gantelius J, Svahn HA
Angew. Chem. Int. Ed. Engl. 55 (15) 4650-4665 [2016-04-04; online 2016-02-19]
Affiliated researcher
Signals and Receptors.
Heldin CH, Lu B, Evans R, Gutkind JS
Cold Spring Harbor Perspectives in Biology 8 (4) a005900 [2016-04-01; online 2016-04-01]
Affiliated researcher
Na+-K+-ATPase, a new class of plasma membrane receptors.
Aperia A, Akkuratov EE, Fontana JM, Brismar H
Am. J. Physiol., Cell Physiol. 310 (7) C491-C495 [2016-04-01; online 2016-01-20]
Affiliated researcher
Genome-wide association and Mendelian randomization study of NT-proBNP in patients with acute coronary syndrome.
Johansson Å, Eriksson N, Lindholm D, ..., Wallentin L, PLATO Investigators
Hum. Mol. Genet. 25 (7) 1447-1456 [2016-04-01; online 2016-01-21]
Affiliated researcher
CopyNumber450kCancer: baseline correction for accurate copy number calling from the 450k methylation array.
Marzouka NA, Nordlund J, Bäcklin CL, ..., Syvänen AC, Carlsson Almlöf J
Bioinformatics 32 (7) 1080-1082 [2016-04-01; online 2015-11-09]
Affiliated researcher
USP7 is a SUMO deubiquitinase essential for DNA replication.
Lecona E, Rodriguez-Acebes S, Specks J, ..., Mendez J, Fernandez-Capetillo O
Nat. Struct. Mol. Biol. 23 (4) 270-277 [2016-04-00; online 2016-03-07]
Affiliated researcher
The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons.
Braasch I, Gehrke AR, Smith JJ, ..., Lindblad-Toh K, Postlethwait JH
Nat. Genet. 48 (4) 427-437 [2016-04-00; online 2016-03-07]
Affiliated researcher
The inflammatory inception of gallbladder cancer.
Espinoza JA, Bizama C, García P, ..., Koshiol J, Roa JC
Biochim. Biophys. Acta 1865 (2) 245-254 [2016-04-00; online 2016-03-12]
Affiliated researcher
The heterogeneity of human CD127(+) innate lymphoid cells revealed by single-cell RNA sequencing.
Björklund ÅK, Forkel M, Picelli S, ..., Sandberg R, Mjösberg J
Nat. Immunol. 17 (4) 451-460 [2016-04-00; online 2016-02-15]
Affiliated researcher
The Need for Speed-Kinetic Limits of Drug Transporters.
Matsson P, Lundquist P, Artursson P
Trends Pharmacol. Sci. 37 (4) 243-245 [2016-04-00; online 2016-02-24]
Role of calcium signaling for GDNF secretion, ureter branching and early nephron formation
Fontana JM, Jess DU, Blom H, Brismar H, Aperia A
The FASEB Journal 30 (S1) - [2016-04-00; online 2016-04-00]
Prognostic indices in chronic lymphocytic leukaemia: where do we stand how do we proceed?
Baliakas P, Mattsson M, Stamatopoulos K, Rosenquist R
J. Intern. Med. 279 (4) 347-357 [2016-04-00; online 2015-12-28]
Affiliated researcher
NgR1: A Tunable Sensor Regulating Memory Formation, Synaptic, and Dendritic Plasticity.
Karlsson TE, Smedfors G, Brodin AT, ..., Brené S, Olson L
Cereb. Cortex 26 (4) 1804-1817 [2016-04-00; online 2016-02-02]
Affiliated researcher
Neuroproteomic profiling of human body fluids.
Häggmark A, Schwenk JM, Nilsson P
Proteomics Clin Appl 10 (4) 485-502 [2016-04-00; online 2015-10-12]
Affiliated researcher
Multiplexed protein profiling by sequential affinity capture.
Ayoglu B, Birgersson E, Mezger A, ..., Nilsson P, Schwenk JM
Proteomics 16 (8) 1251-1256 [2016-04-00; online 2016-03-31]
Affiliated researcher
Identification of a serum protein biomarker panel for the diagnosis of knee osteoarthritis
Lourido L, Ayoglu B, Fernández-Tajes J, ..., Nilsson P, Blanco FJ
Osteoarthritis and Cartilage 24 (-) S23 [2016-04-00; online 2016-04-00]
Fast adaptive local thresholding based on ellipse fit
Ranefall P, Sadanandan SK, Wahlby C
- - (-) 205-208 [2016-04-00; online 2016-04-00]
Evolutionary Origins of Rhizarian Parasites.
Sierra R, Cañas-Duarte SJ, Burki F, ..., Arzul I, Pawlowski J
Mol. Biol. Evol. 33 (4) 980-983 [2016-04-00; online 2015-12-16]
Fabien Burki SciLifeLab Fellow
Endurance Training Alters Expression of Over 3000 Isoforms and 34 Novel Transcripts in Human Skeletal Muscle
Lindholm M, Giacomello S, Solnestam BW, ..., Huss M, Sundberg CJ
The FASEB Journal 30 (S1) - [2016-04-00; online 2016-04-00]
A multiple-phenotype imputation method for genetic studies.
Dahl A, Iotchkova V, Baud A, ..., Kranis A, Marchini J
Nat. Genet. 48 (4) 466-472 [2016-04-00; online 2016-02-22]
Affiliated researcher
Untangling Cortico-Striatal Connectivity and Cross-Frequency Coupling in L-DOPA-Induced Dyskinesia.
Belić JJ, Halje P, Richter U, Petersson P, Hellgren Kotaleski J
Front Syst Neurosci 10 (-) 26 [2016-03-30; online 2016-03-30]
A Facile Synthesis of NODASA-Functionalized Peptide
Naicker T, Albericio F, Dutta J, ..., Kruger H, Govender T
Synlett 27 (11) 1685-1688 [2016-03-30; online 2016-03-30]
Affiliated researcher
Trigger Factor Reduces the Force Exerted on the Nascent Chain by a Cotranslationally Folding Protein.
Nilsson OB, Müller-Lucks A, Kramer G, Bukau B, von Heijne G
J. Mol. Biol. 428 (6) 1356-1364 [2016-03-27; online 2016-02-18]
Affiliated researcher
VEGFR2 pY949 signalling regulates adherens junction integrity and metastatic spread.
Li X, Padhan N, Sjöström EO, ..., Jansson L, Claesson-Welsh L
Nat Commun 7 (-) 11017 [2016-03-23; online 2016-03-23]
Affiliated researcher
System-wide Clinical Proteomics of Breast Cancer Reveals Global Remodeling of Tissue Homeostasis.
Pozniak Y, Balint-Lahat N, Rudolph JD, ..., Barshack I, Geiger T
Cell Systems 2 (3) 172-184 [2016-03-23; online 2016-03-03]
Affiliated researcher
On-Water Synthesis of Biaryl Sulfonyl Fluorides.
Chinthakindi PK, Kruger HG, Govender T, Naicker T, Arvidsson PI
J. Org. Chem. 81 (6) 2618-2623 [2016-03-18; online 2016-02-29]
Affiliated researcher
Biological insertion of computationally designed short transmembrane segments.
Baeza-Delgado C, von Heijne G, Marti-Renom MA, Mingarro I
Sci Rep 6 (-) 23397 [2016-03-18; online 2016-03-18]
Affiliated researcher
Use of Time-Resolved Fluorescence To Improve Sensitivity and Dynamic Range of Gel-Based Proteomics.
Sandberg A, Buschmann V, Kapusta P, Erdmann R, Wheelock ÅM
Anal. Chem. 88 (6) 3067-3074 [2016-03-15; online 2016-02-22]
Affiliated researcher
NOD-like receptor signaling and inflammasome-related pathways are highlighted in psoriatic epidermis.
Tervaniemi MH, Katayama S, Skoog T, ..., Kere J, Elomaa O
Sci Rep 6 (-) 22745 [2016-03-15; online 2016-03-15]
Affiliated researcher
Glycation Reactivity of a Quorum-Sensing Signaling Molecule.
Tsuchikama K, Gooyit M, Harris TL, ..., Kaufmann GF, Janda KD
Angew. Chem. Int. Ed. Engl. 55 (12) 4002-4006 [2016-03-14; online 2016-02-17]
Daniel Globisch SciLifeLab Fellow
Engineering Cellular Metabolism.
Nielsen J, Keasling JD
Cell 164 (6) 1185-1197 [2016-03-10; online 2016-03-12]
Affiliated researcher
Analysis of the Cerebrospinal Fluid Proteome in Alzheimer's Disease.
Khoonsari PE, Häggmark A, Lönnberg M, ..., Kultima K, Shevchenko G
PLoS ONE 11 (3) e0150672 [2016-03-07; online 2016-03-07]
Affiliated researcher
Fast, accurate, and lightweight analysis of BS-treated reads with ERNE 2.
Prezza N, Vezzi F, Käller M, Policriti A
BMC Bioinformatics 17 Suppl 4 (-) 69 [2016-03-02; online 2016-03-02]
Affiliated researcher
Cells release subpopulations of exosomes with distinct molecular and biological properties.
Willms E, Johansson HJ, Mäger I, ..., Wood MJ, Vader P
Sci Rep 6 (-) 22519 [2016-03-02; online 2016-03-02]
Affiliated researcher
An ATM/Wip1-dependent timer controls the minimal duration of a DNA-damage mediated cell cycle arrest
Jaiswal H, Benada J, Müllers E, ..., Macurek L, Lindqvist A
- - (-) - [2016-03-02; online 2016-03-02]
Estrogen receptor beta as target for colorectal cancer prevention.
Williams C, DiLeo A, Niv Y, Gustafsson JÅ
Cancer Lett. 372 (1) 48-56 [2016-03-01; online 2015-12-18]
Affiliated researcher
Comparative proteomics reveals signature metabolisms of exponentially growing and stationary phase marine bacteria
Muthusamy S, Lundin D, Branca RM, ..., Lehtiö J, Pinhassi J
- - (-) - [2016-03-01; online 2016-03-01]
Towards a functional definition of the mitochondrial human proteome.
Fasano M, Alberio T, Babu M, Lundberg E, Urbani A
EuPA Open Proteom 10 (-) 24-27 [2016-03-00; online 2016-01-07]
The metabolic fingerprint of p,p'-DDE and HCB exposure in humans.
Salihovic S, Ganna A, Fall T, ..., Ingelsson E, Lind L
Environ Int 88 (-) 60-66 [2016-03-00; online 2015-12-22]
Affiliated researcher
T-cell receptor-HLA-DRB1 associations suggest specific antigens in pulmonary sarcoidosis.
Grunewald J, Kaiser Y, Ostadkarampour M, ..., Ronninger M, Eklund A
Eur. Respir. J. 47 (3) 898-909 [2016-03-00; online 2015-11-19]
Affiliated researcher
Small protein domains fold inside the ribosome exit tunnel.
Marino J, von Heijne G, Beckmann R
FEBS Lett. 590 (5) 655-660 [2016-03-00; online 2016-02-25]
Affiliated researcher
Second generation sequencing of microRNA in Human Bone Cells treated with Parathyroid Hormone or Dexamethasone.
Laxman N, Rubin CJ, Mallmin H, ..., Tellgren-Roth C, Kindmark A
Bone 84 (-) 181-188 [2016-03-00; online 2015-12-31]
Affiliated researcher
Rapid and straightforward transesterification of sulfonyl carbamates
Isaksson R, Kumpiņa I, Larhed M, Wannberg J
Tetrahedron Letters 57 (13) 1476-1478 [2016-03-00; online 2016-03-00]
Affiliated researcher
Oncogene-Induced Senescence in Pituitary Adenomas--an Immunohistochemical Study.
Manojlovic-Gacic E, Skender-Gazibara M, Popovic V, ..., Pontén F, Casar-Borota O
Endocr. Pathol. 27 (1) 1-11 [2016-03-00; online 2015-11-18]
Affiliated researcher
Normalization of circulating microRNA expression data obtained by quantitative real-time RT-PCR.
Marabita F, de Candia P, Torri A, ..., Abrignani S, Rossi RL
Brief. Bioinformatics 17 (2) 204-212 [2016-03-00; online 2015-08-03]
Affiliated researcher
Identification of novel genetic causes of Rett syndrome-like phenotypes.
Lopes F, Barbosa M, Ameur A, ..., Pinto D, Maciel P
J. Med. Genet. 53 (3) 190-199 [2016-03-00; online 2016-01-06]
Affiliated researcher
Geographical range in liverworts: does sex really matter?
Laenen B, Machac A, Gradstein SR, ..., Shaw J, Vanderpoorten A
J. Biogeogr. 43 (3) 627-635 [2016-03-00; online 2015-11-04]
Affiliated researcher
Gene expression signatures, pathways and networks in carotid atherosclerosis.
Perisic L, Aldi S, Sun Y, ..., Paulsson-Berne G, Hedin U
J. Intern. Med. 279 (3) 293-308 [2016-03-00; online 2015-11-30]
Affiliated researcher
Combined inhibition of DDR1 and Notch signaling is a therapeutic strategy for KRAS-driven lung adenocarcinoma.
Ambrogio C, Gómez-López G, Falcone M, ..., Santamaría D, Barbacid M
Nat. Med. 22 (3) 270-277 [2016-03-00; online 2016-02-08]
Affiliated researcher
Altered DNA methylation of glycolytic and lipogenic genes in liver from obese and type 2 diabetic patients.
Kirchner H, Sinha I, Gao H, ..., Dahlman-Wright K, Zierath JR
Mol Metab 5 (3) 171-183 [2016-03-00; online 2016-01-02]
Affiliated researcher
Whole-exome sequencing in relapsing chronic lymphocytic leukemia: clinical impact of recurrent RPS15 mutations.
Ljungström V, Cortese D, Young E, ..., Sjöblom T, Rosenquist R
Blood 127 (8) 1007-1016 [2016-02-25; online 2015-12-16]
Affiliated researcher
Structures of Two Melanoma-Associated Antigens Suggest Allosteric Regulation of Effector Binding.
Newman JA, Cooper CD, Roos AK, ..., Osman R, Gileadi O
PLoS ONE 11 (2) e0148762 [2016-02-24; online 2016-02-24]
Affiliated researcher
An Efficient Protecting-Group-Free Synthesis of Vinylic Sulfoximines via Horner–Wadsworth–Emmons Reaction
Naicker T, Arvidsson P, Chinthakindi P, ..., Govender T, Kruger H
Synlett 27 (09) 1423-1427 [2016-02-24; online 2016-02-24]
Affiliated researcher
Anoctamin 2 identified as an autoimmune target in multiple sclerosis.
Ayoglu B, Mitsios N, Kockum I, ..., Olsson T, Nilsson P
Proc. Natl. Acad. Sci. U.S.A. 113 (8) 2188-2193 [2016-02-23; online 2016-02-09]
Affiliated researcher
Stepwise nucleosome translocation by RSC remodeling complexes.
Harada BT, Hwang WL, Deindl S, ..., Bartholomew B, Zhuang X
Elife 5 (-) - [2016-02-19; online 2016-02-19]
SciLifeLab Fellow Sebastian Deindl
Bimodal occupancy-frequency distributions uncover the importance of regional dynamics in shaping marine microbial biogeography
Lindh MV, Sjöstedt J, Ekstam B, ..., Legrand C, Pinhassi J
- - (-) - [2016-02-18; online 2016-02-18]
Genomic inference of the metabolism of cosmopolitan subsurface Archaea, Hadesarchaea.
Baker BJ, Saw JH, Lind AE, ..., Teske AP, Ettema TJ
Nat. Microbiol 1 (-) 16002 [2016-02-15; online 2016-02-15]
Affiliated researcher
Exome sequencing in one family with gastric- and rectal cancer.
Thutkawkorapin J, Picelli S, Kontham V, ..., Nilsson D, Lindblom A
BMC Genet. 17 (-) 41 [2016-02-13; online 2016-02-13]
Affiliated researcher
Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1.
Llona-Minguez S, Höglund A, Jacques SA, ..., Scobie M, Helleday T
J. Med. Chem. 59 (3) 1140-1148 [2016-02-11; online 2016-01-27]
Affiliated researcher
Fast Zeta Transforms for Lattices with Few Irreducibles
Björklund A, Husfeldt T, Kaski P, ..., Nederlof J, Parviainen P
TALG ACM Trans. Algorithms 12 (1) 1-19 [2016-02-08; online 2015-12-31]
Affiliated researcher
Systems Proteomics View of the Endogenous Human Claudin Protein Family.
Liu F, Koval M, Ranganathan S, ..., Kelleher NL, Baker MS
J. Proteome Res. 15 (2) 339-359 [2016-02-05; online 2016-01-12]
Affiliated researcher
Proteome-wide survey of the autoimmune target repertoire in autoimmune polyendocrine syndrome type 1.
Landegren N, Sharon D, Freyhult E, ..., Snyder M, Kämpe O
Sci Rep 6 (-) 20104 [2016-02-01; online 2016-02-01]
Affiliated researcher
New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk.
Lu Y, Day FR, Gustafsson S, ..., Kilpeläinen TO, Loos RJ
Nat Commun 7 (-) 10495 [2016-02-01; online 2016-02-01]
Affiliated researcher
Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels.
Kilpeläinen TO, Carli JF, Skowronski AA, ..., Leibel RL, Loos RJ
Nat Commun 7 (-) 10494 [2016-02-01; online 2016-02-01]
Affiliated researcher
The Proteome of Filter-Grown Caco-2 Cells With a Focus on Proteins Involved in Drug Disposition.
Ölander M, Wiśniewski JR, Matsson P, Lundquist P, Artursson P
J Pharm Sci 105 (2) 817-827 [2016-02-00; online 2016-01-09]
Affiliated researcher
TAP-independent self-peptides enhance T cell recognition of immune-escaped tumors.
Doorduijn EM, Sluijter M, Querido BJ, ..., van der Burg SH, van Hall T
J. Clin. Invest. 126 (2) 784-794 [2016-02-00; online 2016-01-19]
Affiliated researcher
Segmentation and Track-Analysis in Time-Lapse Imaging of Bacteria
Sadanandan SK, Baltekin O, Magnusson KEG, ..., Elf J, Wahlby C
IEEE J. Sel. Top. Signal Process. 10 (1) 174-184 [2016-02-00; online 2016-02-00]
Affiliated researcher
Revealing the Mechanism for Conformational Changes from Structurally Rich Ensembles
Orellana L, Yoluk O, Orozco M, Lindahl E
Biophysical Journal 110 (3) 54a [2016-02-00; online 2016-02-00]
Oufti: an integrated software package for high-accuracy, high-throughput quantitative microscopy analysis.
Paintdakhi A, Parry B, Campos M, ..., Surovtsev I, Jacobs-Wagner C
Mol. Microbiol. 99 (4) 767-777 [2016-02-00; online 2015-12-18]
Affiliated researcher
Mechanisms of action of bone morphogenetic proteins in cancer.
Davis H, Raja E, Miyazono K, Tsubakihara Y, Moustakas A
Cytokine Growth Factor Rev. 27 (-) 81-92 [2016-02-00; online 2015-11-24]
Affiliated researcher
From CRYO-EM Densities to Atom Coordinates and Ensembles with Bayes Approach
Blau C, Lenner N, Kutzner C, Grubmuller H, Lindahl E
Biophysical Journal 110 (3) 156a-157a [2016-02-00; online 2016-02-00]
Exome Sequencing of Uterine Leiomyosarcomas Identifies Frequent Mutations in TP53, ATRX, and MED12.
Mäkinen N, Aavikko M, Heikkinen T, ..., Bützow R, Vahteristo P
PLoS Genet 12 (2) e1005850 [2016-02-00; online 2016-02-18]
Affiliated researcher
Decreased levels of stem cell factor in subjects with incident coronary events.
Wigren M, Rattik S, Hultman K, ..., Gonçalves I, Nilsson J
J. Intern. Med. 279 (2) 180-191 [2016-02-00; online 2015-10-14]
Affiliated researcher
Correlating chemical sensitivity and basal gene expression reveals mechanism of action.
Rees MG, Seashore-Ludlow B, Cheah JH, ..., Shamji AF, Schreiber SL
Nat. Chem. Biol. 12 (2) 109-116 [2016-02-00; online 2015-12-14]
Affiliated researcher
Computational Cancer Biology: An Evolutionary Perspective.
Beerenwinkel N, Greenman CD, Lagergren J
PLoS Comput Biol 12 (2) e1004717 [2016-02-00; online 2016-02-04]
Affiliated researcher
Complete Knockout of Endogenous Mdr1 ( Abcb1 ) in MDCK Cells by CRISPR-Cas9
Simoff I, Karlgren M, Backlund M, ..., Matsson P, Artursson P
Journal of Pharmaceutical Sciences 105 (2) 1017-1021 [2016-02-00; online 2016-02-00]
Affiliated researcher
Association between levels of pentraxin 3 and incidence of chronic kidney disease in the elderly.
Sjöberg B, Qureshi AR, Heimbürger O, ..., Bárány P, Ärnlöv J
J. Intern. Med. 279 (2) 173-179 [2016-02-00; online 2015-09-09]
Affiliated researcher
A Single Mutation in GLIC Reveals Both the Potentiating and the Inhibitory Nature of Propofol
Heusser SA, Howard RJ, Pouya I, ..., Harris RA, Lindahl E
Biophysical Journal 110 (3) 456a [2016-02-00; online 2016-02-00]
A Reciprocal Voltage Sensor-To-Pore Coupling in C-Type Inactivation
Conti L, Renhorn J, Gabrielsson A, ..., Lindahl E, Elinder F
Biophysical Journal 110 (3) 104a [2016-02-00; online 2016-02-00]
Multiple dimensions of bacterial diversity unrelated to functioning, stability and multifunctionality
Roger F, Bertilsson S, Langenheder S, Ahmed O, Gamfeldt L
- - (-) - [2016-01-28; online 2016-01-28]
Recent advances in understanding Type 1 Diabetes.
Christoffersson G, Rodriguez-Calvo T, von Herrath M
F1000Res 5 (-) - [2016-01-27; online 2016-01-27]
Gustaf Christoffersson SciLifeLab Fellow
A survey of best practices for RNA-seq data analysis.
Conesa A, Madrigal P, Tarazona S, ..., Zhang X, Mortazavi A
Genome Biol. 17 (-) 13 [2016-01-26; online 2016-01-26]
Affiliated researcher
Exploration of Interfacial Hydration Networks of Target-Ligand Complexes.
Jeszenői N, Bálint M, Horváth I, van der Spoel D, Hetényi C
J Chem Inf Model 56 (1) 148-158 [2016-01-25; online 2016-01-08]
Affiliated researcher
Proadifen sensitizes resistant ovarian adenocarcinoma cells to cisplatin.
Jendželovský R, Jendželovská Z, Hiľovská L, ..., Mikeš J, Fedoročko P
Toxicol. Lett. 243 (-) 56-66 [2016-01-22; online 2015-12-22]
Affiliated researcher
Interferon-γ-induced p27KIP1 binds to and targets MYC for proteasome-mediated degradation.
Bahram F, Hydbring P, Tronnersjö S, ..., Castell A, Larsson LG
Oncotarget 7 (3) 2837-2854 [2016-01-19; online 2015-12-25]
Affiliated researcher
A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration.
de Vries PS, Chasman DI, Sabater-Lleal M, ..., Strachan DP, Dehghan A
Hum. Mol. Genet. 25 (2) 358-370 [2016-01-15; online 2015-11-10]
Affiliated researcher
The protein kinase LKB1 negatively regulates bone morphogenetic protein receptor signaling.
Raja E, Tzavlaki K, Vuilleumier R, ..., Heldin CH, Moustakas A
Oncotarget 7 (2) 1120-1143 [2016-01-12; online 2015-12-25]
Affiliated researcher
Simultaneous Multiplexed Measurement of RNA and Proteins in Single Cells.
Darmanis S, Gallant CJ, Marinescu VD, ..., Westermark B, Landegren U
Cell Reports 14 (2) 380-389 [2016-01-12; online 2015-12-31]
Affiliated researcher
Influence of pre-existing inflammation on the outcome of acute coronary syndrome: a cross-sectional study.
Odeberg J, Freitag M, Forssell H, ..., Råstam L, Lindblad U
BMJ Open 6 (1) e009968 [2016-01-12; online 2016-01-12]
Affiliated researcher
Genome-wide identification of Wig-1 mRNA targets by RIP-Seq analysis.
Bersani C, Huss M, Giacomello S, ..., Lui WO, Wiman KG
Oncotarget 7 (2) 1895-1911 [2016-01-12; online 2015-12-18]
Affiliated researcher
Cancer-Specific Synthetic Lethality between ATR and CHK1 Kinase Activities.
Sanjiv K, Hagenkort A, Calderón-Montaño JM, ..., Altun M, Helleday T
Cell Reports 14 (2) 298-309 [2016-01-12; online 2015-12-31]
Affiliated researcher
The (elusive) role of the SMC5/6 complex.
Fernandez-Capetillo O
Cell Cycle 15 (6) 775-776 [2016-01-09; online 2016-01-09]
Case definitions in Swedish register data to identify systemic lupus erythematosus.
Arkema EV, Jönsen A, Rönnblom L, ..., Sjöwall C, Simard JF
BMJ Open 6 (1) e007769 [2016-01-04; online 2016-01-04]
Affiliated researcher
CRISPRz: a database of zebrafish validated sgRNAs.
Varshney GK, Zhang S, Pei W, ..., Sood R, Burgess SM
Nucleic Acids Res. 44 (D1) D822-D826 [2016-01-04; online 2015-10-04]
Affiliated researcher
Antigen Selection Shapes the T-cell Repertoire in Chronic Lymphocytic Leukemia.
Vardi A, Agathangelidis A, Stalika E, ..., Sutton LA, Stamatopoulos K
Clin. Cancer Res. 22 (1) 167-174 [2016-01-01; online 2015-09-02]
Affiliated researcher
A carbon budget for the Amundsen Sea Polynya, Antarctica: Estimating net community production and export in a highly productive polar ecosystem
Yager P, Sherrell R, Stammerjohn S, ..., Swalethorp R, van Dijken G
- 4 (-) - [2016-01-01; online 2016-12-09]
hTERT promoter methylation in pituitary adenomas.
Köchling M, Ewelt C, Fürtjes G, ..., Stummer W, Brokinkel B
Brain Tumor Pathol 33 (1) 27-34 [2016-01-00; online 2015-09-21]
Affiliated researcher
Protein Biomarkers for Insulin Resistance and Type 2 Diabetes Risk in Two Large Community Cohorts.
Nowak C, Sundström J, Gustafsson S, ..., Ingelsson E, Fall T
Diabetes 65 (1) 276-284 [2016-01-00; online 2015-09-29]
Affiliated researcher
Out of southern East Asia: the natural history of domestic dogs across the world.
Wang GD, Zhai W, Yang HC, ..., Savolainen P, Zhang YP
Cell Res. 26 (1) 21-33 [2016-01-00; online 2015-12-15]
Affiliated researcher
Mutations in FLVCR2 associated with Fowler syndrome and survival beyond infancy.
Kvarnung M, Taylan F, Nilsson D, ..., Nordgren A, Syk Lundberg E
Clin. Genet. 89 (1) 99-103 [2016-01-00; online 2015-03-04]
Affiliated researcher
Large-scale non-targeted metabolomic profiling in three human population-based studies
Ganna A, Fall T, Salihovic S, ..., Pawitan Y, Ingelsson E
Metabolomics 12 (1) - [2016-01-00; online 2015-11-07]
Affiliated researcher
Increased lanosterol turnover: a metabolic burden for daunorubicin-resistant leukemia cells.
Stäubert C, Krakowsky R, Bhuiyan H, ..., Broom O, Nordström A
Med. Oncol. 33 (1) 6 [2016-01-00; online 2015-12-23]
Affiliated researcher
Genetic heterogeneity in rhabdomyosarcoma revealed by SNP array analysis.
Walther C, Mayrhofer M, Nilsson J, ..., Gisselsson D, Mertens F
Genes Chromosomes Cancer 55 (1) 3-15 [2016-01-00; online 2015-10-20]
Affiliated researcher
F11 is associated with recurrent VTE in women. A prospective cohort study.
Bruzelius M, Ljungqvist M, Bottai M, ..., Lärfars G, Odeberg J
Thromb. Haemost. 115 (2) 406-414 [2016-01-00; online 2015-10-01]
Affiliated researcher
A minimalistic microbial food web in an excavated deep subsurface clay rock.
Bagnoud A, de Bruijn I, Andersson AF, ..., Schwyn B, Bernier-Latmani R
FEMS Microbiol. Ecol. 92 (1) - [2016-01-00; online 2015-11-04]
Affiliated researcher
Structural Variation Detection with Read Pair Information—An Improved Null-Hypothesis Reduces Bias
Sahlin K, Frånberg M, Arvestad L
- - (-) 176-188 [2016-00-00; online 2016-04-08]
Strategies to Map the Microbiome of Freshwater Lakes: Sampling and Context
Bertilsson S
- - (-) 199-217 [2016-00-00; online 2016-05-03]
Rolling Circle Amplification with Padlock Probes for In Situ Detection of RNA Analytes
Mezger A, Kühnemund M, Nilsson M
- - (-) 99-105 [2016-00-00; online 2016-11-10]
Optofludics in microstructured fibers combining particle elasto-inertial focusing and fluorescence
Etcheverry S, Faridi A, Ramachandraiah H, ..., Laurell F, Russom A
- - (-) SW4G.6 [2016-00-00; online 2016-00-00]
Graph Centrality Based Prediction of Cancer Genes
Weishaupt H, Johansson P, Engström C, ..., Silvestrov S, Swartling FJ
- - (-) 275-311 [2016-00-00; online 2017-02-11]
Fractal Dimension versus Process Complexity
Joosten JJ, Soler-Toscano F, Zenil H
Advances in Mathematical Physics 2016 (-) 1-21 [2016-00-00; online 2016-00-00]
Affiliated researcher
Comparison of Flow Cytometry and Image-Based Screening for Cell Cycle Analysis
Matuszewski DJ, Sintorn IM, Puigvert JC, Wählby C
- - (-) 623-630 [2016-00-00; online 2016-07-01]

Publications 9.5.1