Publications 2020

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1224 publications

PubMed DOI Crossref
Whole-genome sequencing of recurrent neuroblastoma reveals somatic mutations that affect key players in cancer progression and telomere maintenance.
Fransson S, Martinez-Monleon A, Johansson M, ..., Kogner P, Martinsson T
Sci Rep 10 (1) 22432 [2020-12-31; online 2020-12-31]
PubMed DOI Crossref
The serine protease HtrA plays a key role in heat-induced dispersal of pneumococcal biofilms.
Chao Y, Bergenfelz C, Sun R, ..., Achour A, Hakansson AP
Sci Rep 10 (1) 22455 [2020-12-31; online 2020-12-31]
PubMed DOI Crossref
TGFBR3L-An Uncharacterised Pituitary Specific Membrane Protein Detected in the Gonadotroph Cells in Non-Neoplastic and Tumour Tissue.
Sjöstedt E, Kolnes AJ, Olarescu NC, ..., Bollerslev J, Casar-Borota O
Cancers (Basel) 13 (1) - [2020-12-31; online 2020-12-31]
PubMed DOI Crossref
Defining eligible patients for allele-selective chemotherapies targeting NAT2 in colorectal cancer.
Rendo V, Kundu S, Rameika N, ..., Stoimenov I, Sjöblom T
Sci Rep 10 (1) 22436 [2020-12-31; online 2020-12-31]
DOI Crossref
scMomentum: Inference of Cell-Type-Specific Regulatory Networks and Energy Landscapes
Soto LM, Bernal-Tamayo JP, Lehmann R, ..., Kiani NA, Tegner J
- - (-) - [2020-12-30; online 2020-12-30]
DOI Crossref
The Broad Role of Nkx3.2 in the Development of the Zebrafish Axial Skeleton
Waldmann L, Leyhr J, Zhang H, ..., Allalou A, Haitina T
- - (-) - [2020-12-30; online 2020-12-30]
PubMed DOI Crossref
Broadly Active Antiviral Compounds Disturb Zika Virus Progeny Release Rescuing Virus-Induced Toxicity in Brain Organoids.
Pettke A, Tampere M, Pronk R, ..., Mirazimi A, Puumalainen MR
Viruses 13 (1) - [2020-12-29; online 2020-12-29]
DOI Crossref
Locally adaptive inversions modulate genetic variation at different geographic scales in a seaweed fly
Mérot C, Berdan E, Cayuela H, ..., Wellenreuther M, Bernatchez L
- - (-) - [2020-12-28; online 2020-12-28]
PubMed DOI Crossref
Exploitation of dihydroorotate dehydrogenase (DHODH) and p53 activation as therapeutic targets: A case study in polypharmacology.
Ladds MJGW, Popova G, Pastor-Fernández A, ..., Lane DP, Laín S
J Biol Chem 295 (52) 17935-17949 [2020-12-25; online 2020-09-08]
PubMed DOI Crossref
Development and external validation of a COVID-19 mortality risk prediction algorithm: a multicentre retrospective cohort study.
Mei J, Hu W, Chen Q, ..., Yue J, Wang QL
BMJ Open 10 (12) e044028 [2020-12-24; online 2020-12-24]
DDLS Fellow Qiaoli Wang
DOI Crossref
Multiplexed experimental strategies for fragment library screening using SPR biosensors
FitzGerald EA, Vagrys D, Opassi G, ..., de Esch IJP, Danielson UH
- - (-) - [2020-12-23; online 2020-12-23]
PubMed DOI Crossref
Erratum for Hugerth et al., "Assessment of In Vitro and In Silico Protocols for Sequence-Based Characterization of the Human Vaginal Microbiome".
Hugerth LW, Pereira M, Zha Y, ..., Schuppe-Koistinen I, Engstrand L
mSphere 5 (6) - [2020-12-23; online 2020-12-23]
DDLS Fellow Luisa Hugerth
DOI Crossref
Author response: Identification of ligand-specific G protein-coupled receptor states and prediction of downstream efficacy via data-driven modeling
Fleetwood O, Carlsson J, Delemotte L
- - (-) - [2020-12-23; online 2020-12-23]
Jens Carlsson Lucie Delemotte SciLifeLab Fellow
DOI Crossref
SARS-CoV-2 infections among personnel providing home care services for the elderly in Stockholm, Sweden
Hassan SS, Seigerud Å, Mühr LSA, ..., Lundgren KC, Dillner J
- - (-) - [2020-12-22; online 2020-12-22]
DOI Crossref
Peer Review Report For: Semi-automated analysis of dot blots using ImageJ/Fiji [version 1; peer review: 2 approved with reservations]
- - (-) - [2020-12-22; online 2020-12-22]
PubMed DOI Crossref
Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch.
Lehmann LC, Bacic L, Hewitt G, ..., Boulton SJ, Deindl S
Cell Reports 33 (12) 108529 [2020-12-22; online 2020-12-29]
SciLifeLab Fellow Sebastian Deindl
PubMed DOI Crossref
Ileocolonic Histopathological and Microbial Alterations in the Irritable Bowel Syndrome: A Nested Community Case-Control Study.
Talley NJ, Alexander JL, Walker MM, ..., Powell N, Andreasson A
Clin Transl Gastroenterol 12 (1) e00296 [2020-12-22; online 2020-12-22]
DDLS Fellow Luisa Hugerth
PubMed DOI Crossref
Complex subsurface hydrothermal fluid mixing at a submarine arc volcano supports distinct and highly diverse microbial communities.
Reysenbach AL, St John E, Meneghin J, ..., Diehl A, Bach W
Proc. Natl. Acad. Sci. U.S.A. 117 (51) 32627-32638 [2020-12-22; online 2020-12-04]
DOI Crossref
Aggregation and immobilisation of membrane proteins interplay with local lipid order in the plasma membrane of T cells
Urbančič I, Schiffelers L, Jenkins E, ..., Sezgin E, Eggeling C
- - (-) - [2020-12-22; online 2020-12-22]
Erdinc Sezgin SciLifeLab Fellow
DOI Crossref
Genomic instability is an early event driving chromatin reorganization and escape from oncogene-induced senescence
Zampetidis C, Galanos P, Angelopoulou A, ..., Papantonis A, Gorgoulis V
- - (-) - [2020-12-20; online 2020-12-20]
DOI Crossref
The chaperonin GroESL facilitates Caulobacter crescentus cell division by supporting the function of the actin homologue FtsA
Schroeder K, Heinrich K, Neuwirth I, Jonas K
- - (-) - [2020-12-18; online 2020-12-18]
Kristina Jonas SciLifeLab Fellow
PubMed DOI Crossref
Preclinical Evaluation of the Copper-64 Labeled GRPR-Antagonist RM26 in Comparison with the Cobalt-55 Labeled Counterpart for PET-Imaging of Prostate Cancer.
Baun C, Mitran B, Rinne SS, ..., Orlova A, Thisgaard H
Molecules 25 (24) - [2020-12-18; online 2020-12-18]
DOI Crossref
Peer Review Report For: Semi-automated analysis of dot blots using ImageJ/Fiji [version 1; peer review: 2 approved with reservations]
- - (-) - [2020-12-18; online 2020-12-18]
PubMed DOI Crossref
MuscleAtlasExplorer: a web service for studying gene expression in human skeletal muscle.
Asplund O, Rung J, Groop L, Prasad B R, Hansson O
Database (Oxford) 2020 (-) - [2020-12-18; online 2020-12-19]
PubMed DOI Crossref
Editorial: Redox Homeostasis and Cancer.
Sinha M, Mardinoglu A, Ghose J, Singh K
Oxid Med Cell Longev 2020 (-) 5487381 [2020-12-18; online 2020-12-18]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
SOCIODEMOGRAPHIC CHARACTERISTICS AND COVID-19 TESTING RATES: SPATIO-TEMPORAL PATTERNS AND IMPACT OF TEST ACCESSIBILITY IN SWEDEN
Kennedy B, Varotsis G, Hammar U, ..., Björk J, Fall T
- - (-) - [2020-12-16; online 2020-12-16]
PubMed DOI Crossref
Revamping Space-omics in Europe.
Madrigal P, Gabel A, Villacampa A, ..., da Silveira WA, Herranz R
Cell Syst 11 (6) 555-556 [2020-12-16; online 2020-11-25]
DOI Crossref
Protein engineering in the big data era: harnessing near-redundant structural data
Flores SC, Alexiou A, Glaros A
- - (-) - [2020-12-16; online 2020-12-16]
DOI Crossref
The evolutionary history of topological variations in the CPA/AT superfamily
Govindarajan S, Bassot C, Lamb J, ..., Huang Y, Elofsson A
- - (-) - [2020-12-15; online 2020-12-15]
PubMed DOI Crossref
The developmental relationship between teeth and dermal odontodes in the most primitive bony fish Lophosteus.
Chen D, Blom H, Sanchez S, ..., Märss T, Ahlberg PE
Elife 9 (-) - [2020-12-15; online 2020-12-15]
PubMed DOI Crossref
Screening of Multiple Biomarkers Associated With Ischemic Stroke in Atrial Fibrillation.
Hijazi Z, Wallentin L, Lindbäck J, ..., Oldgren J, Siegbahn A
J Am Heart Assoc 9 (24) e018984 [2020-12-15; online 2020-12-09]
PubMed DOI Crossref
Managing Coronavirus Disease 2019 Spread With Voluntary Public Health Measures: Sweden as a Case Study for Pandemic Control.
Kamerlin SCL, Kasson PM
Clin Infect Dis 71 (12) 3174-3181 [2020-12-15; online 2020-07-02]
DOI Crossref
Informing NMR experiments with molecular dynamics simulations to characterize the dominant activated state of the KcsA ion channel
Pérez-Conesa S, Keeler EG, Zhang D, Delemotte L, McDermott AE
- - (-) - [2020-12-15; online 2020-12-15]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Cryo-EM structure of native human uromodulin, a zona pellucida module polymer.
Stsiapanava A, Xu C, Brunati M, ..., Wu B, Jovine L
EMBO J. 39 (24) e106807 [2020-12-15; online 2020-11-16]
PubMed DOI Crossref
An angular motion of a conserved four-helix bundle facilitates alternating access transport in the TtNapA and EcNhaA transporters.
Masrati G, Mondal R, Rimon A, ..., Lindahl E, Ben-Tal N
Proc. Natl. Acad. Sci. U.S.A. 117 (50) 31850-31860 [2020-12-15; online 2020-11-30]
DOI Crossref
A blueprint for high affinity SARS-CoV-2 Mpro inhibitors from activity-based compound library screening guided by analysis of protein dynamics
Gossen J, Albani S, Hanke A, ..., Kokh DB, Rossetti G
- - (-) - [2020-12-15; online 2020-12-15]
DOI Crossref
The SEQC2 Epigenomics Quality Control (EpiQC) Study: Comprehensive Characterization of Epigenetic Methods, Reproducibility, and Quantification
Foox J, Nordlund J, Lalancette C, ..., Deng Y, Mason CE
- - (-) - [2020-12-14; online 2020-12-14]
DOI Crossref
Screening for high amounts of SARS-CoV-2 identifies pre-symptomatic subjects among healthy healthcare workers
Dillner J, Elfström KM, Blomqvist J, ..., Mühr LSA, Lundgren KC
- - (-) - [2020-12-14; online 2020-12-14]
DOI Crossref
Plastic-degrading potential across the global microbiome correlates with recent pollution trends
Zrimec J, Kokina M, Jonasson S, Zorrilla F, Zelezniak A
- - (-) - [2020-12-13; online 2020-12-13]
Aleksej Zelezniak SciLifeLab Fellow
DOI Crossref
Three-dimensional spatial transcriptomics uncovers cell type dynamics in the rheumatoid arthritis synovium
Vickovic S, Schapiro D, Carlberg K, ..., Regev A, Ståhl PL
- - (-) - [2020-12-11; online 2020-12-11]
Sanja Vickovic SciLifeLab Fellow
PubMed DOI Crossref
Parallel Factor Analysis Enables Quantification and Identification of Highly Convolved Data-Independent-Acquired Protein Spectra.
Buric F, Zrimec J, Zelezniak A
Patterns (N Y) 1 (9) 100137 [2020-12-11; online 2020-11-05]
Aleksej Zelezniak SciLifeLab Fellow
DOI Crossref
Functional crosstalk between phosphorylation and disease-causing mutations in the cardiac sodium channel Na v 1.5
Galleano I, Harms H, Choudhury K, ..., Delemotte L, Pless SA
bioRxiv - (-) - [2020-12-11; online 2020-12-11]
Lucie Delemotte SciLifeLab Fellow
DOI Crossref
Common variants near the bradykinin receptor B 2 gene are associated with angioedema induced by angiotensin-converting-enzyme inhibitor treatment - a genome wide association study
Ghouse J, Ahlberg G, Andreasen L, ..., Bundgaard H, Olesen MS
- - (-) - [2020-12-11; online 2020-12-11]
DOI Crossref
A porcine brain-wide RNA editing landscape
Huang J, Lin L, Dong Z, ..., Bolund L, Luo Y
- - (-) - [2020-12-11; online 2020-12-11]
DOI Crossref
A multi-omics study of circulating phospholipid markers of blood pressure
Liu J, de Vries PS, Greco M. FD, ..., Dehghan A, Demirkan A
- - (-) - [2020-12-11; online 2020-12-11]
PubMed DOI Crossref
A New Era for Space Life Science: International Standards for Space Omics Processing.
Rutter L, Barker R, Bezdan D, ..., Herranz R, Muratani M
Patterns (N Y) 1 (9) 100148 [2020-12-11; online 2020-11-25]
PubMed DOI Crossref
The shared risk of diabetes between dog and cat owners and their pets: register based cohort study.
Delicano RA, Hammar U, Egenvall A, ..., Fall T, Kennedy B
BMJ 371 (-) m4337 [2020-12-10; online 2020-12-10]
PubMed DOI Crossref
Novel Broad-Spectrum Antiviral Inhibitors Targeting Host Factors Essential for Replication of Pathogenic RNA Viruses.
Tampere M, Pettke A, Salata C, ..., Jafari R, Puumalainen MR
Viruses 12 (12) - [2020-12-10; online 2020-12-10]
PubMed DOI Crossref
Cell-cell fusion of mesenchymal cells with distinct differentiations triggers genomic and transcriptomic remodelling toward tumour aggressiveness.
Delespaul L, Gélabert C, Lesluyes T, ..., Lartigue L, Chibon F
Sci Rep 10 (1) 21634 [2020-12-10; online 2020-12-10]
DOI Crossref
Bridging the Gap Between Atomistic Molecular Dynamics Simulations and Wet-lab Experimental Techniques: Applications to Membrane Proteins
Delemotte L
- - (-) 247-286 [2020-12-10; online 2020-12-10]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Variant in NHLRC2 leads to increased hnRNP C2 in developing neurons and the hippocampus of a mouse model of FINCA disease.
Hiltunen AE, Kangas SM, Ohlmeier S, ..., Uusimaa J, Hinttala R
Mol. Med. 26 (1) 123 [2020-12-09; online 2020-12-09]
PubMed DOI Crossref
Precise Triggering and Chemical Control of Single-Virus Fusion within Endosomes.
Haldar S, Okamoto K, Dunning RA, Kasson PM
J. Virol. 95 (1) - [2020-12-09; online 2020-12-09]
PubMed DOI Crossref
Automated Removal of Non-homologous Sequence Stretches with PREQUAL.
Irisarri I, Burki F, Whelan S
Methods in molecular biology (Clifton, N.J.) 2231 (-) 147-162 [2020-12-09; online 2020-12-09]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Single-Stranded Oligonucleotide-Mediated Inhibition of Respiratory Syncytial Virus Infection.
Pålsson SA, Dondalska A, Bergenstråhle J, ..., Galloux M, Spetz AL
Front Immunol 11 (-) 580547 [2020-12-08; online 2020-12-08]
PubMed DOI Crossref
Circulating miRNA Spaceflight Signature Reveals Targets for Countermeasure Development.
Malkani S, Chin CR, Cekanaviciute E, ..., Mason CE, Beheshti A
Cell Reports 33 (10) 108448 [2020-12-08; online 2020-11-25]
DDLS Fellow Marc Friedländer Marcel Tarbier SciLifeLab Fellow
PubMed DOI Crossref
Capillary leakage provides nutrients and antioxidants for rapid pneumococcal proliferation in influenza-infected lower airways.
Sender V, Hentrich K, Pathak A, ..., Normark S, Henriques-Normark B
Proc. Natl. Acad. Sci. U.S.A. 117 (49) 31386-31397 [2020-12-08; online 2020-11-23]
DOI Crossref
Using Relion software within Scipion framework
Sharov G, Morado DR, Carroni M, de la Rosa-Trevín JM
- - (-) - [2020-12-07; online 2020-12-07]
PubMed DOI Crossref
Leaky severe combined immunodeficiency in mice lacking non-homologous end joining factors XLF and MRI.
Castañeda-Zegarra S, Zhang Q, Alirezaylavasani A, ..., Yao R, Oksenych V
Aging (Albany NY) 12 (23) 23578-23597 [2020-12-07; online 2020-12-07]
PubMed DOI Crossref
Mitochondrial DNA Sequence Diversity in Mammals: A Correlation between the Effective and Census Population Sizes.
James J, Eyre-Walker A
Genome Biol Evol 12 (12) 2441-2449 [2020-12-06; online 2020-10-24]
DDLS Fellow Jennifer James
PubMed DOI Crossref
BMP signaling is a therapeutic target in ovarian cancer.
Fukuda T, Fukuda R, Tanabe R, ..., Miyazono K, Heldin CH
Cell death discovery 6 (1) 139 [2020-12-05; online 2020-12-05]
PubMed DOI Crossref
The Role of Intratumor Heterogeneity in the Response of Metastatic Non-Small Cell Lung Cancer to Immune Checkpoint Inhibitors.
Nicoś M, Krawczyk P, Crosetto N, Milanowski J
Front Oncol 10 (-) 569202 [2020-12-04; online 2020-12-04]
DOI Crossref
NGSpeciesID: DNA barcode and amplicon consensus generation from long-read sequencing data
Sahlin K, Lim M, Prost S
AUTHOREA - (-) - [2020-12-04; online 2020-12-04]
Kristoffer Sahlin SciLifeLab Fellow
PubMed DOI Crossref
Longitudinal Plasma Protein Profiling Using Targeted Proteomics and Recombinant Protein Standards.
Kotol D, Hunt H, Hober A, ..., Uhlén M, Edfors F
J. Proteome Res. 19 (12) 4815-4825 [2020-12-04; online 2020-09-04]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
Enhanced Validation of Antibodies Enables the Discovery of Missing Proteins.
Sivertsson Å, Lindström E, Oksvold P, ..., Uhlén M, Lindskog C
J. Proteome Res. 19 (12) 4766-4781 [2020-12-04; online 2020-11-10]
PubMed DOI Crossref
Targeting OGG1 arrests cancer cell proliferation by inducing replication stress.
Visnes T, Benítez-Buelga C, Cázares-Körner A, ..., Berglund UW, Helleday T
Nucleic Acids Res. 48 (21) 12234-12251 [2020-12-02; online 2020-11-20]
DOI Crossref
Profiling of extracellular small RNAs highlights a strong bias towards non-vesicular secretion
Sork H, Conceicao M, Corso G, ..., Andaloussi SE, Mäger I
- - (-) - [2020-12-02; online 2020-12-02]
PubMed DOI Crossref
Moose genomes reveal past glacial demography and the origin of modern lineages.
Dussex N, Alberti F, Heino MT, ..., Dalén L, Díez-Del-Molino D
BMC Genomics 21 (1) 854 [2020-12-02; online 2020-12-02]
DDLS Fellow Tom van der Valk
PubMed DOI Crossref
Microbial model communities: To understand complexity, harness the power of simplicity.
Bengtsson-Palme J
Comput Struct Biotechnol J 18 (-) 3987-4001 [2020-12-02; online 2020-12-02]
DDLS Fellow Johan Bengtsson-Palme
DOI Crossref
Direct RNA targeted transcriptomic profiling in tissue using Hybridization-based RNA In Situ Sequencing (HybRISS)
Lee H, Salas SM, Gyllborg D, Nilsson M
- - (-) - [2020-12-02; online 2020-12-02]
PubMed DOI Crossref
Bromopyrylium Derivatization Facilitates Identification by Mass Spectrometry Imaging of Monoamine Neurotransmitters and Small Molecule Neuroactive Compounds.
Shariatgorji R, Nilsson A, Strittmatter N, ..., Goodwin RJA, Andrén PE
J. Am. Soc. Mass Spectrom. 31 (12) 2553-2557 [2020-12-02; online 2020-07-21]
PubMed DOI Crossref
Whole blood co-expression modules associate with metabolic traits and type 2 diabetes: an IMI-DIRECT study.
Gudmundsdottir V, Pedersen HK, Mazzoni G, ..., Pedersen O, Brunak S
Genome Med 12 (1) 109 [2020-12-01; online 2020-12-01]
PubMed DOI Crossref
Unravelling the mechanism of pH-regulation in dinoflagellate luciferase.
Kamerlin N, Delcey MG, Lindh R
Int J Biol Macromol 164 (-) 2671-2680 [2020-12-01; online 2020-08-19]
DOI Crossref
Semi-automated analysis of dot blots using ImageJ/Fiji
Klemm AH
F1000Res 9 (-) 1385 [2020-12-01; online 2020-12-01]
DOI Crossref
Guidelines for accurate genotyping of SARS-CoV-2 using amplicon-based sequencing of clinical samples
Kubik S, Marques AC, Xing X, ..., Willig A, Xu Z
- - (-) - [2020-12-01; online 2020-12-01]
SciLifeLab Fellow
PubMed DOI Crossref
Expression of the stem cell marker CD133 in malignant meningioma.
Maier AD, Mirian C, Bartek J, ..., Broholm H, Mathiesen TI
Clin Neuropathol 40 (3) 151-159 [2020-12-01; online 2020-12-01]
PubMed DOI Crossref
Deep learning suggests that gene expression is encoded in all parts of a co-evolving interacting gene regulatory structure.
Zrimec J, Börlin CS, Buric F, ..., Töpel M, Zelezniak A
Nat Commun 11 (1) 6141 [2020-12-01; online 2020-12-01]
PubMed DOI Crossref
Assessment of Posttraumatic Stress Disorder and Educational Achievement in Sweden.
Vilaplana-Pérez A, Sidorchuk A, Pérez-Vigil A, ..., Mataix-Cols D, Fernández de la Cruz L
JAMA Netw Open 3 (12) e2028477 [2020-12-01; online 2020-12-01]
PubMed DOI Crossref
Amplification-free long-read sequencing reveals unforeseen CRISPR-Cas9 off-target activity.
Höijer I, Johansson J, Gudmundsson S, ..., Gyllensten U, Ameur A
Genome Biol. 21 (1) 290 [2020-12-01; online 2020-12-01]
DOI Crossref
Update on Performance Analysis of Different Computational Architectures: Molecular Dynamics in Application to Protein-Protein Interactions
JSFI 7 (4) - [2020-12-00; online 2020-12-00]
PubMed DOI Crossref
The methylation landscape and its role in domestication and gene regulation in the chicken.
Höglund A, Henriksen R, Fogelholm J, ..., Jensen P, Wright D
Nat Ecol Evol 4 (12) 1713-1724 [2020-12-00; online 2020-09-21]
PubMed DOI Crossref
The environment drives microbial trait variability in aquatic habitats.
Beier S, Andersson AF, Galand PE, ..., McMahon K, Bertilsson S
Mol. Ecol. 29 (23) 4605-4617 [2020-12-00; online 2020-10-18]
PubMed DOI Crossref
The Long Noncoding RNA CCAT2 Induces Chromosomal Instability Through BOP1-AURKB Signaling.
Chen B, Dragomir MP, Fabris L, ..., Ajani JA, Calin GA
Gastroenterology 159 (6) 2146-2162.e33 [2020-12-00; online 2020-08-15]
PubMed DOI Crossref
Structural and functional consequences of reversible lipid asymmetry in living membranes.
Doktorova M, Symons JL, Levental I
Nat. Chem. Biol. 16 (12) 1321-1330 [2020-12-00; online 2020-11-16]
DDLS Fellow Milka Doktorova
PubMed DOI Crossref
Spatial Characterization of the Human Centrosome Proteome Opens Up New Horizons for a Small but Versatile Organelle.
Danielsson F, Mahdessian D, Axelsson U, ..., Thul PJ, Lundberg E
Proteomics 20 (23) e1900361 [2020-12-00; online 2020-08-26]
PubMed DOI Crossref
S100A6 is a critical regulator of hematopoietic stem cells.
Grahn THM, Niroula A, Végvári Á, ..., Zubarev RA, Karlsson S
Leukemia 34 (12) 3323-3337 [2020-12-00; online 2020-06-19]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
Recent advances in single-molecule fluorescence microscopy render structural biology dynamic.
Bacic L, Sabantsev A, Deindl S
Curr. Opin. Struct. Biol. 65 (-) 61-68 [2020-12-00; online 2020-07-04]
SciLifeLab Fellow Sebastian Deindl
DOI Crossref
Proceedings of the EuBIC-MS 2020 Developers’ Meeting
Ashwood C, Bittremieux W, Deutsch EW, ..., Webel H, Willems S
EuPA Open Proteom 24 (-) 1-6 [2020-12-00; online 2020-12-00]
DOI Crossref
PDMS leaching and its implications for on-chip studies focusing on bone regeneration applications
Carter SSD, Atif AR, Kadekar S, ..., Tenje M, Mestres G
Organs-on-a-Chip 2 (-) 100004 [2020-12-00; online 2020-12-00]
PubMed DOI Crossref
Mutation-independent Proteomic Signatures of Pathological Progression in Murine Models of Duchenne Muscular Dystrophy.
van Westering TLE, Johansson HJ, Hanson B, ..., Aoki Y, Roberts TC
Mol. Cell Proteomics 19 (12) 2047-2068 [2020-12-00; online 2020-09-29]
PubMed DOI Crossref
Metabolomic Profile in HFpEF vs HFrEF Patients.
Hage C, Löfgren L, Michopoulos F, ..., Persson H, Linde C
J Card Fail 26 (12) 1050-1059 [2020-12-00; online 2020-08-01]
PubMed DOI Crossref
Increased sperm production linked to competition in the maternal social environment.
Hobson L, Hurst JL, Stockley P
R Soc Open Sci 7 (12) 201171 [2020-12-00; online 2020-12-16]
PubMed DOI Crossref
Improved computational analysis of ribosome dynamics from 5'P degradome data using fivepseq.
Nersisyan L, Ropat M, Pelechano V
NAR Genomics and Bioinformatics 2 (4) lqaa099 [2020-12-00; online 2020-11-24]
SciLifeLab Fellow
PubMed DOI Crossref
Immunostimulatory oncolytic virotherapy for multiple myeloma targeting 4-1BB and/or CD40.
Wenthe J, Naseri S, Hellström AC, ..., Eriksson E, Loskog A
Cancer Gene Ther. 27 (12) 948-959 [2020-12-00; online 2020-05-01]
PubMed DOI Crossref
Identification of areas of grading difficulties in prostate cancer and comparison with artificial intelligence assisted grading.
Egevad L, Swanberg D, Delahunt B, ..., Clements M, Eklund M
Virchows Arch. 477 (6) 777-786 [2020-12-00; online 2020-06-15]
DDLS Fellow Kimmo Kartasalo
PubMed DOI Crossref
IL-16 processing in sentinel node regulatory T cells is a factor in bladder cancer immunity.
Krantz D, Mints M, Winerdal M, ..., Sherif A, Winqvist O
Scand. J. Immunol. 92 (6) e12926 [2020-12-00; online 2020-08-30]
PubMed DOI Crossref
Genome-wide detection of DNA double-strand breaks by in-suspension BLISS.
Bouwman BAM, Agostini F, Garnerone S, ..., Roukos V, Crosetto N
Nat Protoc 15 (12) 3894-3941 [2020-12-00; online 2020-11-02]
Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
Genome-wide association study of angioedema induced by angiotensin-converting enzyme inhibitor and angiotensin receptor blocker treatment.
Rasmussen ER, Hallberg P, Baranova EV, ..., Palmer CNA, Wadelius M
Pharmacogenomics J. 20 (6) 770-783 [2020-12-00; online 2020-02-21]
PubMed DOI Crossref
Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity.
Yaghootkar H, Zhang Y, Spracklen CN, ..., Loos RJF, Kilpeläinen TO
Diabetes 69 (12) 2806-2818 [2020-12-00; online 2020-09-11]
PubMed DOI Crossref
Genetic Predisposition to Coronary Artery Disease in Type 2 Diabetes Mellitus.
van Zuydam NR, Ladenvall C, Voight BF, ..., Palmer CNA, SUMMIT Steering Committee; CARDIOGRAMplusC4D Steering Committee*
Circ Genom Precis Med 13 (6) e002769 [2020-12-00; online 2020-08-13]
PubMed DOI Crossref
Generation of two human iPSC lines (UUIGPi013-A and UUIPGi014-A) from cases with Down syndrome and full trisomy for chromosome 21 (T21).
Schuster J, Hoeber J, Sobol M, ..., Annerén G, Dahl N
Stem Cell Res 49 (-) 102081 [2020-12-00; online 2020-11-07]
PubMed DOI Crossref
Exome Sequencing Reveals Common and Rare Variants in F5 Associated With ACE Inhibitor and Angiotensin Receptor Blocker-Induced Angioedema.
Maroteau C, Siddiqui MK, Veluchamy A, ..., Palmer CNA, PREDICTION-ADR
Clin. Pharmacol. Ther. 108 (6) 1195-1202 [2020-12-00; online 2020-07-18]
PubMed DOI Crossref
Dysregulation in Akt/mTOR/HIF-1 signaling identified by proteo-transcriptomics of SARS-CoV-2 infected cells.
Appelberg S, Gupta S, Svensson Akusjärvi S, ..., Mirazimi A, Neogi U
Emerg Microbes Infect 9 (1) 1748-1760 [2020-12-00; online 2020-07-22]
PubMed DOI Crossref
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.
Surendran P, Feofanova EV, Lahrouchi N, ..., Munroe PB, Howson JMM
Nat. Genet. 52 (12) 1314-1332 [2020-12-00; online 2020-11-23]
PubMed DOI Crossref
Comprehensive Investigation of Circulating Biomarkers and Their Causal Role in Atherosclerosis-Related Risk Factors and Clinical Events.
Zanetti D, Gustafsson S, Assimes TL, Ingelsson E
Circ Genom Precis Med 13 (6) e002996 [2020-12-00; online 2020-10-30]
PubMed DOI Crossref
Colonization factor CS30 from enterotoxigenic Escherichia coli binds to sulfatide in human and porcine small intestine.
Von Mentzer A, Zalem D, Chrienova Z, Teneberg S
Virulence 11 (1) 381-390 [2020-12-00; online 2020-04-05]
Astrid von Mentzer DDLS Fellow
PubMed DOI Crossref
Clear mortality gap caused by graft macrosteatosis in Chinese patients after cadaveric liver transplantation.
Liu Z, Wang W, Zhuang L, ..., Zhou L, Zheng S
Hepatobiliary Surg Nutr 9 (6) 739-758 [2020-12-00; online 2020-12-11]
PubMed DOI Crossref
Calmodulin acts as a state-dependent switch to control a cardiac potassium channel opening.
Kang PW, Westerlund AM, Shi J, ..., Delemotte L, Cui J
Sci Adv 6 (50) - [2020-12-00; online 2020-12-11]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
CRISPR and Long-Read Sequencing: A Perfect Match.
Ameur A
CRISPR J 3 (6) 425-427 [2020-12-00; online 2020-11-30]
PubMed DOI Crossref
Association and Familial Coaggregation of Idiopathic Dystonia With Psychiatric Outcomes.
Martino D, Brander G, Svenningsson P, Larsson H, de la Cruz LF
Mov Disord 35 (12) 2270-2278 [2020-12-00; online 2020-09-17]
PubMed DOI Crossref
Antibiotic use and risk of colorectal cancer: a systematic review and dose-response meta-analysis.
Simin J, Fornes R, Liu Q, ..., Engstrand L, Brusselaers N
Br. J. Cancer 123 (12) 1825-1832 [2020-12-00; online 2020-09-24]
PubMed DOI Crossref
Aniridia with PAX6 mutations and narcolepsy.
Berntsson SG, Kristoffersson A, Daniilidou M, ..., Hallböök F, Landtblom AM
J Sleep Res 29 (6) e12982 [2020-12-00; online 2020-01-14]
PubMed DOI Crossref
Aberrant splicing due to a novel RPS7 variant causes Diamond-Blackfan Anemia associated with spontaneous remission and meningocele.
Akram T, Fatima A, Klar J, ..., Schuster J, Dahl N
Int J Hematol 112 (6) 894-899 [2020-12-00; online 2020-08-09]
PubMed DOI Crossref
A transcription factor glial cell missing (Gcm) in the freshwater crayfish Pacifastacus leniusculus.
Junkunlo K, Söderhäll K, Söderhäll I
Dev. Comp. Immunol. 113 (-) 103782 [2020-12-00; online 2020-07-15]
PubMed DOI Crossref
A reference map of potential determinants for the human serum metabolome.
Bar N, Korem T, Weissbrod O, ..., Pedersen O, Segal E
Nature 588 (7836) 135-140 [2020-12-00; online 2020-11-11]
DOI Crossref
A practical guide to microfabrication and patterning of hydrogels for biomimetic cell culture scaffolds
Tenje M, Cantoni F, Porras Hernández AM, ..., Antfolk M, Pohlit H
Organs-on-a-Chip 2 (-) 100003 [2020-12-00; online 2020-12-00]
PubMed DOI Crossref
A community-based transcriptomics classification and nomenclature of neocortical cell types.
Yuste R, Hawrylycz M, Aalling N, ..., Zeng H, Lein E
Nat. Neurosci. 23 (12) 1456-1468 [2020-12-00; online 2020-08-26]
PubMed DOI Crossref
Post-load glucose subgroups and associated metabolic traits in individuals with type 2 diabetes: An IMI-DIRECT study.
Obura M, Beulens JWJ, Slieker R, ..., Rutters F, IMI-DIRECT Consortium
PLoS ONE 15 (11) e0242360 [2020-11-30; online 2020-11-30]
PubMed DOI Crossref
Evaluation of Single-Molecule Sequencing Technologies for Structural Variant Detection in Two Swedish Human Genomes.
Fatima N, Petri A, Gyllensten U, Feuk L, Ameur A
Genes (Basel) 11 (12) - [2020-11-30; online 2020-11-30]
PubMed DOI Crossref
Author Correction: Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples.
Bailey MH, Meyerson WU, Dursi LJ, ..., Ding L, PCAWG Consortium
Nat Commun 11 (1) 6232 [2020-11-30; online 2020-11-30]
DOI Crossref
Phenotypic plasticity, population structure and adaptation in a young weed species with a worldwide distribution
Cornille A, Tiret M, Salcedo A, ..., Wright SI, Lascoux M
- - (-) - [2020-11-28; online 2020-11-28]
Pascal Milesi SciLifeLab Fellow
DOI Crossref
Architecture and mechanism of metazoan retromer:SNX3 tubular coat assembly
Leneva N, Kovtun O, Morado DR, Briggs JAG, Owen DJ
- - (-) - [2020-11-28; online 2020-11-28]
DOI Crossref
The selfing syndrome overshadows other differences when comparing fitness across Capsella species
Orsucci M, Vanikiotis T, Guerrina M, ..., Glémin S, Lascoux M
- - (-) - [2020-11-27; online 2020-11-27]
PubMed DOI Crossref
Maturation of Monocyte-Derived DCs Leads to Increased Cellular Stiffness, Higher Membrane Fluidity, and Changed Lipid Composition.
Lühr JJ, Alex N, Amon L, ..., Guck J, Dudziak D
Front Immunol 11 (-) 590121 [2020-11-27; online 2020-11-27]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Empty mesoporous silica particles significantly delay disease progression and extend survival in a mouse model of ALS.
Leyton-Jaimes MF, Ivert P, Hoeber J, ..., Israelson A, Kozlova EN
Sci Rep 10 (1) 20675 [2020-11-26; online 2020-11-26]
PubMed DOI Crossref
Universal Single-Residue Terminal Labels for Fluorescent Live Cell Imaging of Microproteins.
Lafranchi L, Schlesinger D, Kimler KJ, Elsässer SJ
Journal of the American Chemical Society 142 (47) 20080-20087 [2020-11-25; online 2020-11-11]
SciLifeLab Fellow Simon Elsässer
DOI Crossref
Peer Review Report For: COVID-19 and beyond: a call for action and audacious solidarity to all the citizens and nations, it is humanity’s fight [version 1; peer review: 3 approved with reservations]
- - (-) - [2020-11-25; online 2020-11-25]
DOI Crossref
Peer Review Report For: COVID-19 and beyond: a call for action and audacious solidarity to all the citizens and nations, it is humanity’s fight [version 1; peer review: 3 approved with reservations]
- - (-) - [2020-11-25; online 2020-11-25]
DOI Crossref
Faculty Opinions recommendation of Genome-wide Nucleotide-Resolution Mapping of DNA Replication Patterns, Single-Strand Breaks, and Lesions by GLOE-Seq.
Elsässer S
- - (-) - [2020-11-25; online 2020-11-13]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Application of Cryo-EM for Visualization of Mitoribosomes.
Singh V, Amunts A
Methods in molecular biology (Clifton, N.J.) 2192 (-) 197-210 [2020-11-25; online 2020-11-25]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Variations among Viruses in Influent Water and Effluent Water at a Wastewater Plant over One Year as Assessed by Quantitative PCR and Metagenomics.
Wang H, Neyvaldt J, Enache L, ..., Bergstedt O, Norder H
Applied and environmental microbiology 86 (24) - [2020-11-24; online 2020-11-24]
DOI Crossref
The anti-inflammatory peptide Catestatin blocks chemotaxis
Muntjewerff EM, Parv K, Mahata SK, ..., Christoffersson G, van den Bogaart G
- - (-) - [2020-11-24; online 2020-11-24]
Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
High CD45 expression of CD8+ and CD4+ T cells correlates with the size of HIV-1 reservoir in blood.
Petkov S, Bekele Y, Lakshmikanth T, ..., Brodin P, Chiodi F
Sci Rep 10 (1) 20425 [2020-11-24; online 2020-11-24]
PubMed DOI Crossref
Comparative interactomes of HSF1 in stress and disease reveal a role for CTCF in HSF1-mediated gene regulation.
Burchfiel ET, Vihervaara A, Guertin MJ, Gomez-Pastor R, Thiele DJ
J Biol Chem 296 (-) 100097 [2020-11-24; online 2020-11-24]
Anniina Vihervaara SciLifeLab Fellow
PubMed DOI Crossref
Exploring microfluidics as a tool to evaluate the biological properties of a titanium alloy under dynamic conditions.
Carter SD, Barbe L, Tenje M, Mestres G
Biomater Sci 8 (22) 6309-6321 [2020-11-21; online 2020-10-06]
DOI Crossref
STATegra: Multi-omics data integration - A conceptual scheme and a bioinformatics pipeline
Planell N, Lagani V, Sebastian-Leon P, ..., Tegner J, Gomez-Cabrero D
- - (-) - [2020-11-20; online 2020-11-20]
PubMed DOI Crossref
Low Shear Stress Increases Recombinant Protein Production and High Shear Stress Increases Apoptosis in Human Cells.
Zhan C, Bidkhori G, Schwarz H, ..., Rockberg J, Chotteau V
iScience 23 (11) 101653 [2020-11-20; online 2020-10-07]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Comparative dietary sulfated metabolome analysis reveals unknown metabolic interactions of the gut microbiome and the human host.
Correia MSP, Jain A, Alotaibi W, ..., Rodriguez-Mateos A, Globisch D
Free Radic. Biol. Med. 160 (-) 745-754 [2020-11-20; online 2020-09-11]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
Amino Acid Modified RNA Bases as Building Blocks of an Early Earth RNA-Peptide World.
Nainytė M, Müller F, Ganazzoli G, ..., Globisch D, Carell T
Chemistry 26 (65) 14856-14860 [2020-11-20; online 2020-10-14]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
Lung Cancer Immunotherapy in Transplant Patients and in Patients With Autoimmune Diseases.
Kubiatowski T, Nicoś M, Krawczyk P
Front Oncol 10 (-) 568081 [2020-11-19; online 2020-11-19]
PubMed DOI Crossref
Ligand design by targeting a binding site water.
Matricon P, Suresh RR, Gao ZG, ..., Jacobson KA, Carlsson J
Chem Sci 12 (3) 960-968 [2020-11-19; online 2020-11-19]
Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Inactivation of mediator complex protein 22 in podocytes results in intracellular vacuole formation, podocyte loss and premature death.
Rodriguez PQ, Unnersjö-Jess D, Zambrano SS, ..., Ebarasi L, Patrakka J
Sci Rep 10 (1) 20037 [2020-11-18; online 2020-11-18]
PubMed DOI Crossref
Exploring autoantibody signatures in brain tissue from patients with severe mental illness.
Just D, Månberg A, Mitsios N, ..., Nilsson P, Carlström EL
Transl Psychiatry 10 (1) 401 [2020-11-18; online 2020-11-18]
PubMed DOI Crossref
Assessment of In Vitro and In Silico Protocols for Sequence-Based Characterization of the Human Vaginal Microbiome.
Hugerth LW, Pereira M, Zha Y, ..., Schuppe-Koistinen I, Engstrand L
mSphere 5 (6) - [2020-11-18; online 2020-11-18]
DDLS Fellow Luisa Hugerth
DOI Crossref
A Modular Workflow for Model Building, Analysis, and Parameter Estimation in Systems Biology and Neuroscience
Santos JPG, Pajo K, Trpevski D, ..., Kotaleski JH, Kramer A
- - (-) - [2020-11-18; online 2020-11-18]
PubMed DOI Crossref
Royleanone Derivatives From Plectranthus spp. as a Novel Class of P-Glycoprotein Inhibitors.
Garcia C, Isca VMS, Pereira F, ..., Afonso CAM, Rijo P
Front. Pharmacol. 11 (-) 557789 [2020-11-17; online 2020-11-17]
DOI Crossref
Revealing interspecies transmission barriers of avian influenza A viruses
Naguib MM, Eriksson P, Jax E, ..., Järhult JD, Ellström P
- - (-) - [2020-11-17; online 2020-11-17]
PubMed DOI Crossref
Lipoprotein Particles Interact with Membranes and Transfer Their Cargo without Receptors.
Plochberger B, Sych T, Weber F, ..., Stangl H, Sezgin E
Biochemistry 59 (45) 4421-4428 [2020-11-17; online 2020-11-04]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Distinct oligodendrocyte populations have spatial preference and different responses to spinal cord injury.
Floriddia EM, Lourenço T, Zhang S, ..., Nilsson M, Castelo-Branco G
Nat Commun 11 (1) 5860 [2020-11-17; online 2020-11-17]
DOI Crossref
SARS-CoV-2 serological tests can generate false positive results for samples from patients with chronic inflammatory diseases
Kharlamova N, Dunn N, Bedri SK, ..., Fink K, Fogdell-Hahn A
- - (-) - [2020-11-13; online 2020-11-13]
DOI Crossref
Drug repurposing improves disease targeting 11-fold on average. New insights from network module targeting and its application to COVID-19.
Rivero I, Castresana M, Guala D, Sonnhammer E
- - (-) - [2020-11-13; online 2020-11-13]
PubMed DOI Crossref
The Immunology of Multisystem Inflammatory Syndrome in Children with COVID-19.
Consiglio CR, Cotugno N, Sardh F, ..., Palma P, Brodin P
Cell 183 (4) 968-981.e7 [2020-11-12; online 2020-09-06]
Camila Consiglio DDLS Fellow
DOI Crossref
Multiomics and digital monitoring during lifestyle changes reveal independent dimensions of human biology and health
Marabita F, James T, Karhu A, ..., Sallinen R, Kallioniemi O
- - (-) - [2020-11-12; online 2020-11-12]
DOI Crossref
Loop Dynamics and Enzyme Catalysis in Protein Tyrosine Phosphatases
Crean R, Biler M, van der Kamp M, Hengge AC, Kamerlin SCL
- - (-) - [2020-11-12; online 2020-11-12]
DOI Crossref
Comprehensive dataset of shotgun metagenomes from stratified freshwater lakes and ponds
Buck M, Garcia SL, Vidal LF, ..., Bertilsson S, Peura S
- - (-) - [2020-11-12; online 2020-11-12]
Sarahi Garcia Sari Peura SciLifeLab Fellow
PubMed DOI Crossref
Association of aberrant ASNS imprinting with asparaginase sensitivity and chromosomal abnormality in childhood BCP-ALL.
Watanabe A, Miyake K, Nordlund J, ..., Sugita K, Inukai T
Blood 136 (20) 2319-2333 [2020-11-12; online 2020-06-24]
PubMed DOI Crossref
Artificial intelligence application for rapid fabrication of size-tunable PLGA microparticles in microfluidics.
Damiati SA, Rossi D, Joensson HN, Damiati S
Sci Rep 10 (1) 19517 [2020-11-11; online 2020-11-11]
PubMed DOI Crossref
Wild boar behaviour during live-trap capture in a corral-style trap: implications for animal welfare.
Fahlman Å, Lindsjö J, Norling TA, ..., Ågren EO, Bergvall UA
Acta Vet Scand 62 (1) 59 [2020-11-10; online 2020-11-10]
PubMed DOI Crossref
Acceptability of self- collection for human papillomavirus detection in the Eastern Cape, South Africa.
Taku O, Meiring TL, Gustavsson I, ..., Gyllensten U, Williamson AL
PLoS ONE 15 (11) e0241781 [2020-11-10; online 2020-11-10]
PubMed DOI Crossref
Uncovering cancer gene regulation by accurate regulatory network inference from uninformative data.
Seçilmiş D, Hillerton T, Morgan D, ..., Nordling TEM, Sonnhammer ELL
NPJ Syst Biol Appl 6 (1) 37 [2020-11-09; online 2020-11-09]
PubMed DOI Crossref
Targeted sequencing reveals the somatic mutation landscape in a Swedish breast cancer cohort.
Mathioudaki A, Ljungström V, Melin M, ..., Sjöblom T, Lindblad-Toh K
Sci Rep 10 (1) 19304 [2020-11-09; online 2020-11-09]
PubMed DOI Crossref
Demographic Processes Linked to Genetic Diversity and Positive Selection across a Species' Range.
Willi Y, Fracassetti M, Bachmann O, Van Buskirk J
Plant Commun 1 (6) 100111 [2020-11-09; online 2020-09-11]
PubMed DOI Crossref
DNA methylation in infants with low and high body fatness.
Henriksson P, Lentini A, Altmäe S, ..., Nestor CE, Löf M
BMC Genomics 21 (1) 769 [2020-11-09; online 2020-11-09]
Antonio Lentini DDLS Fellow
DOI Crossref
Point-of-care detection of SARS-CoV-2 in nasopharyngeal swab samples using an integrated smartphone-based centrifugal microfluidic platform
Soares RRG, Akhtar AS, Pinto IF, ..., Pelechano V, Russom A
- - (-) - [2020-11-06; online 2020-11-06]
SciLifeLab Fellow
DOI Crossref
Persistence of SARS-CoV-2 specific B- and T-cell responses in convalescent COVID-19 patients 6-8 months after the infection
Sherina N, Piralla A, Du L, ..., Marcotte H, Pan-Hammarström Q
- - (-) - [2020-11-06; online 2020-11-06]
DOI Crossref
Proteogenomic Subtyping of Chronic Lymphocytic Leukemia Identifies a Novel Poor Outcome Subgroup with a Distinct Drug Response Profile
Herbst SA, Vesterlund M, Jafari R, ..., Lehtiö J, Dietrich S
Blood 136 (Supplement 1) 10-11 [2020-11-05; online 2020-11-05]
DOI Crossref
Prediction of Relapse after Allogeneic Stem Cell Transplantation Using Individualized Minimal Residual Markers; The Prospective Nordic Study NMDSG14B
Tobiasson M, Pandzic T, Illman J, ..., Dybedal I, Hellstrom Lindberg E
Blood 136 (Supplement 1) 5-6 [2020-11-05; online 2020-11-05]
PubMed DOI Crossref
Multi-layer assembly of cellulose nanofibrils in a microfluidic device for the selective capture and release of viable tumor cells from whole blood.
Kumar T, Soares RRG, Ali Dholey L, ..., Pettersson T, Russom A
Nanoscale 12 (42) 21788-21797 [2020-11-05; online 2020-10-27]
PubMed DOI Crossref
Lysine-specific demethylase 1A restricts ex vivo propagation of human HSCs and is a target of UM171.
Subramaniam A, Žemaitis K, Talkhoncheh MS, ..., Zubarev RA, Larsson J
Blood 136 (19) 2151-2161 [2020-11-05; online 2020-06-26]
DOI Crossref
Karonudib Has Potent Anti-Tumor Effects in Preclinical Models of B-Cell Lymphoma
Oksvold MP, Warpman Berglund U, Gad H, ..., Helleday T, Våtsveen TK
Blood 136 (Supplement 1) 18-19 [2020-11-05; online 2020-11-05]
DOI Crossref
Insight into P-glycoprotein activity of royleanones from <em>Plectranthus</em> spp.
Rijo P, Isca V, Ntungwe E, ..., Candeias N, Afonso C
- - (-) 7279 [2020-11-05; online 2020-11-05]
DOI Crossref
Identification of a novel fold type in CPA/AT transporters by ab-initio structure prediction
Bassot C, Govindarajan S, Lamb J, Elofsson A
- - (-) - [2020-11-05; online 2020-11-05]
DOI Crossref
Graphene FET Sensors for Alzheimer’s Disease Protein Biomarker Clusterin Detection
Bungon T, Haslam C, Damiati S, ..., Charmet J, Awan SA
- - (-) 14 [2020-11-05; online 2020-11-05]
DOI Crossref
Genomic and Transcriptomic Characterization of Adult and Pediatric Relapsed Acute Myeloid Leukemia Reveals Novel Therapeutic Targets
Stratmann S, Yones SA, Sun J, ..., Cavelier L, Holmfeldt L
Blood 136 (Supplement 1) 37-38 [2020-11-05; online 2020-11-05]
PubMed DOI Crossref
Genomic Characterization of Salmonella Minnesota Clonal Lineages Associated with Poultry Production in Brazil.
Kipper D, Carroll LM, Mascitti AK, ..., Ikuta N, Lunge VR
Animals (Basel) 10 (11) - [2020-11-05; online 2020-11-05]
DDLS Fellow Laura Carroll
PubMed DOI Crossref
Commonly used clinical chemistry tests as mortality predictors: Results from two large cohort studies.
Lind L, Zanetti D, Högman M, Sundman L, Ingelsson E
PLoS ONE 15 (11) e0241558 [2020-11-05; online 2020-11-05]
DOI Crossref
Clonal Hematopoiesis Is Associated with Increased Risk for Therapy-Related Myeloid Neoplasms in Chronic Lymphocytic Leukemia Patients Treated with Chemo(immuno)Therapy
Voso MT, Pandzic T, Iskas M, ..., Fabiani E, Baliakas P
Blood 136 (Supplement 1) 19-20 [2020-11-05; online 2020-11-05]
PubMed DOI Crossref
Point-of-Care Approaches for Meningitis Diagnosis in a Low-Resource Setting (Southwestern Uganda): Observational Cohort Study Protocol of the "PI-POC" Trial.
Gaudenzi G, Kumbakumba E, Rasti R, ..., Mwanga-Amumpaire J, Alfvén T
JMIR Res Protoc 9 (11) e21430 [2020-11-04; online 2020-11-04]
PubMed DOI Crossref
Novel Effective Bacillus cereus Group Species "Bacillus clarus" Is Represented by Antibiotic-Producing Strain ATCC 21929 Isolated from Soil.
Méndez Acevedo M, Carroll LM, Mukherjee M, ..., Dudley EG, Kovac J
mSphere 5 (6) - [2020-11-04; online 2020-11-04]
DDLS Fellow Laura Carroll
PubMed DOI Crossref
Metabolic characterization of plasma and cyst fluid from cystic precursors to pancreatic cancer patients reveal metabolic signatures of bacterial infection.
Morgell A, Reisz JA, Ateeb Z, ..., Sällberg Chen M, D'Alessandro A
medRxiv - (-) - [2020-11-04; online 2020-11-04]
PubMed DOI Crossref
MYC as a driver of stochastic chromatin networks: implications for the fitness of cancer cells.
Sumida N, Sifakis EG, Kiani NA, ..., Göndör A, Ohlsson R
Nucleic Acids Res. 48 (19) 10867-10876 [2020-11-04; online 2020-10-15]
PubMed DOI Crossref
Hybridization-based in situ sequencing (HybISS) for spatially resolved transcriptomics in human and mouse brain tissue.
Gyllborg D, Langseth CM, Qian X, ..., Lein ES, Nilsson M
Nucleic Acids Res. 48 (19) e112 [2020-11-04; online 2020-09-30]
DOI Crossref
The meadow jumping mouse genome and transcriptome suggest mechanisms of hibernation
Cong Q, Brem EA, Zhang J, ..., Malaney JL, Israelsen WJ
- - (-) - [2020-11-03; online 2020-11-03]
PubMed DOI Crossref
Redesigning Solvatochromic Probe Laurdan for Imaging Lipid Order Selectively in Cell Plasma Membranes.
Danylchuk DI, Sezgin E, Chabert P, Klymchenko AS
Anal. Chem. 92 (21) 14798-14805 [2020-11-03; online 2020-10-12]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
PRDX1 Counteracts Catastrophic Telomeric Cleavage Events That Are Triggered by DNA Repair Activities Post Oxidative Damage.
Ahmed W, Lingner J
Cell Reports 33 (5) 108347 [2020-11-03; online 2020-11-05]
PubMed DOI Crossref
Naming the untouchable - environmental sequences and niche partitioning as taxonomical evidence in fungi.
Kalsoom Khan F, Kluting K, Tångrot J, ..., Ryberg M, Rosling A
IMA Fungus 11 (1) 23 [2020-11-03; online 2020-11-03]
PubMed DOI Crossref
MNK2 governs the macrophage antiinflammatory phenotype.
Bartish M, Tong D, Pan Y, ..., Larsson O, Rolny C
Proc. Natl. Acad. Sci. U.S.A. 117 (44) 27556-27565 [2020-11-03; online 2020-10-19]
DOI Crossref
Experimental evolution of adaptive divergence under varying degrees of gene flow
Tusso S, Nieuwenhuis BPS, Weissensteiner B, Immler S, Wolf JBW
- - (-) - [2020-11-03; online 2020-11-03]
PubMed DOI Crossref
Cross-validated Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging Quantitation Protocol for a Pharmaceutical Drug and Its Drug-Target Effects in the Brain Using Time-of-Flight and Fourier Transform Ion Cyclotron Resonance Analyzers.
Källback P, Vallianatou T, Nilsson A, ..., Svenningsson P, Andrén PE
Anal. Chem. 92 (21) 14676-14684 [2020-11-03; online 2020-10-21]
PubMed DOI Crossref
Computational Analysis of Alzheimer Amyloid Plaque Composition in 2D- and Elastically Reconstructed 3D-MALDI MS Images.
Enzlein T, Cordes J, Munteanu B, ..., Chávez-Gutiérrez L, Hopf C
Anal. Chem. 92 (21) 14484-14493 [2020-11-03; online 2020-10-14]
SciLifeLab Fellow Wojciech Michno
PubMed DOI Crossref
Bridging of nucleosome-proximal DNA double-strand breaks by PARP2 enhances its interaction with HPF1.
Gaullier G, Roberts G, Muthurajan UM, ..., Rae PS, Luger K
PLoS ONE 15 (11) e0240932 [2020-11-03; online 2020-11-03]
PubMed DOI Crossref
Reprogrammed mRNA translation drives resistance to therapeutic targeting of ribosome biogenesis.
Kusnadi EP, Trigos AS, Cullinane C, ..., Kang J, Pearson RB
EMBO J. 39 (21) e105111 [2020-11-02; online 2020-09-18]
PubMed DOI Crossref
Enhanced Collagen Deposition in the Duodenum of Patients with Hyaline Fibromatosis Syndrome and Protein Losing Enteropathy.
van Rijn JM, Werner L, Aydemir Y, ..., Middendorp S, Shouval DS
Int J Mol Sci 21 (21) - [2020-11-02; online 2020-11-02]
PubMed DOI Crossref
Intestinal estrogen receptor beta suppresses colon inflammation and tumorigenesis in both sexes.
Hases L, Indukuri R, Birgersson M, ..., Archer A, Williams C
Cancer Lett. 492 (-) 54-62 [2020-11-01; online 2020-07-23]
PubMed DOI Crossref
Interspecific Gene Flow and the Evolution of Specialization in Black and White Rhinoceros.
Moodley Y, Westbury MV, Russo IM, ..., Dalén L, Bruford MW
Mol. Biol. Evol. 37 (11) 3105-3117 [2020-11-01; online 2020-06-26]
PubMed DOI Crossref
Tracking the motion of the KV1.2 voltage sensor reveals the molecular perturbations caused by a de novo mutation in a case of epilepsy.
Pantazis A, Kaneko M, Angelini M, ..., Saitta SC, Olcese R
J. Physiol. (Lond.) 598 (22) 5245-5269 [2020-11-00; online 2020-09-21]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
The proliferative history shapes the DNA methylome of B-cell tumors and predicts clinical outcome.
Duran-Ferrer M, Clot G, Nadeu F, ..., Campo E, Martín-Subero JI
Nat Cancer 1 (11) 1066-1081 [2020-11-00; online 2020-11-02]
PubMed DOI Crossref
Slight Deuterium Enrichment in Water Acts as an Antioxidant: Is Deuterium a Cell Growth Regulator?
Zhang X, Wang J, Zubarev RA
Mol. Cell Proteomics 19 (11) 1790-1804 [2020-11-00; online 2020-08-07]
PubMed DOI Crossref
Significance of host heparanase in promoting tumor growth and metastasis.
Zhang GL, Gutter-Kapon L, Ilan N, ..., Li JP, Vlodavsky I
Matrix Biol. 93 (-) 25-42 [2020-11-00; online 2020-06-11]
PubMed DOI Crossref
Sahelian pastoralism from the perspective of variants associated with lactase persistence.
Priehodová E, Austerlitz F, Čížková M, ..., Schlebusch CM, Černý V
Am. J. Phys. Anthropol. 173 (3) 423-436 [2020-11-00; online 2020-08-19]
PubMed DOI Crossref
SCRINSHOT enables spatial mapping of cell states in tissue sections with single-cell resolution.
Sountoulidis A, Liontos A, Nguyen HP, ..., Nilsson M, Samakovlis C
PLoS Biol. 18 (11) e3000675 [2020-11-00; online 2020-11-20]
PubMed DOI Crossref
Quantification of aromatase binding in the female human brain using [11 C]cetrozole positron emission tomography.
Jonasson M, Nordeman P, Eriksson J, ..., Lubberink M, Comasco E
J Neurosci Res 98 (11) 2208-2218 [2020-11-00; online 2020-08-06]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Progressive Cactus is a multiple-genome aligner for the thousand-genome era.
Armstrong J, Hickey G, Diekhans M, ..., Zhang G, Paten B
Nature 587 (7833) 246-251 [2020-11-00; online 2020-11-11]
PubMed DOI Crossref
Prevalence, distribution and predictive value of XPO1 mutation in a real-life chronic lymphocytic leukaemia cohort.
Tueur G, Lazarian G, Eclache V, ..., Cymbalista F, Baran-Marszak F
Br. J. Haematol. 191 (3) e90-e94 [2020-11-00; online 2020-08-13]
PubMed DOI Crossref
Perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) induce epigenetic alterations and promote human breast cell carcinogenesis in vitro.
Pierozan P, Cattani D, Karlsson O
Arch. Toxicol. 94 (11) 3893-3906 [2020-11-00; online 2020-07-22]
Oskar Karlsson SciLifeLab Fellow
DOI Crossref
P.719 Investigation of long-term effects of ouabain administration in mice, and analysis of ouabain-induced gene expression changes in a neuronal culture
Lopachev A, Volnova AB, Timoshina YA, ..., Fedorova TN, Gainetdinov RR
Eur Neuropsychopharmacol 40 (-) S408-S409 [2020-11-00; online 2020-11-00]
PubMed DOI Crossref
LifeTime and improving European healthcare through cell-based interceptive medicine.
Rajewsky N, Almouzni G, Gorski SA, ..., Voet T, LifeTime Community Working Groups
Nature 587 (7834) 377-386 [2020-11-00; online 2020-09-07]
DOI Crossref
Implications for tetraspanin-enriched microdomain assembly based on structures of CD9 with EWI-F
Oosterheert W, Xenaki KT, Neviani V, ..., van Bergen en Henegouwen PM, Gros P
Life Sci. Alliance 3 (11) e202000883 [2020-11-00; online 2020-09-21]
DDLS Fellow Nicholas Pearce
PubMed DOI Crossref
Identification and rescue of a tRNA wobble inosine deficiency causing intellectual disability disorder.
Ramos J, Proven M, Halvardson J, ..., Thuresson AC, Fu D
RNA 26 (11) 1654-1666 [2020-11-00; online 2020-08-06]
PubMed DOI Crossref
Human G-MDSCs are neutrophils at distinct maturation stages promoting tumor growth in breast cancer.
Mehmeti-Ajradini M, Bergenfelz C, Larsson AM, ..., Bexell D, Leandersson K
Life Sci. Alliance 3 (11) - [2020-11-00; online 2020-09-21]
PubMed DOI Crossref
High-density lipoprotein characteristics and coronary artery disease: a Mendelian randomization study.
Prats-Uribe A, Sayols-Baixeras S, Fernández-Sanlés A, ..., Hernáez Á, Elosua R
Metabolism 112 (-) 154351 [2020-11-00; online 2020-09-04]
PubMed DOI Crossref
Evaluation of the chemopreventive potentials of ezetimibe and aspirin in a novel mouse model of gallbladder preneoplasia.
Rosa L, Lobos-González L, Muñoz-Durango N, ..., Espinoza JA, Roa JC
Mol Oncol 14 (11) 2834-2852 [2020-11-00; online 2020-09-17]
PubMed DOI Crossref
Epilepsy syndromes, etiologies, and the use of next-generation sequencing in epilepsy presenting in the first 2 years of life: A population-based study.
Stödberg T, Tomson T, Barbaro M, ..., Åmark P, Wedell A
Epilepsia 61 (11) 2486-2499 [2020-11-00; online 2020-09-23]
DOI Crossref
Elevated protein expression levels of KRAS in Pancreatic Ductal Adenocarcinoma (PDAC) are associated with better prognosis
Stålberg S, Silwal-Pandit L, Hamfjord J, Lehtiö J, Kure E
Pancreatology 20 (-) S129-S130 [2020-11-00; online 2020-11-00]
PubMed DOI Crossref
EV-transported microRNAs of Schistosoma mansoni and Fasciola hepatica: Potential targets in definitive hosts.
Ovchinnikov VY, Kashina EV, Mordvinov VA, Fromm B
Infect. Genet. Evol. 85 (-) 104528 [2020-11-00; online 2020-09-04]
PubMed DOI Crossref
Dense sampling of bird diversity increases power of comparative genomics.
Feng S, Stiller J, Deng Y, ..., Paten B, Zhang G
Nature 587 (7833) 252-257 [2020-11-00; online 2020-11-11]
PubMed DOI Crossref
Cytogenetically visible inversions are formed by multiple molecular mechanisms.
Pettersson M, Grochowski CM, Wincent J, ..., Carvalho CMB, Lindstrand A
Hum. Mutat. 41 (11) 1979-1998 [2020-11-00; online 2020-10-01]
PubMed DOI Crossref
Correction to: Perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) induce epigenetic alterations and promote human breast cell carcinogenesis in vitro.
Pierozan P, Cattani D, Karlsson O
Arch. Toxicol. 94 (11) 3907-3909 [2020-11-00; online 2020-08-15]
Oskar Karlsson SciLifeLab Fellow
PubMed DOI Crossref
Complete response with combined BRAF and MEK inhibition in BRAF mutated advanced low-grade serous ovarian carcinoma.
Tholander B, Koliadi A, Botling J, ..., Öberg K, Ullenhag GJ
Ups. J. Med. Sci. 125 (4) 325-329 [2020-11-00; online 2020-10-10]
PubMed DOI Crossref
Chondrocytes respond to an altered heparan sulfate composition with distinct changes of heparan sulfate structure and increased levels of chondroitin sulfate.
Bachvarova V, Dierker T, Esko J, ..., Kjellen L, Vortkamp A
Matrix Biol. 93 (-) 43-59 [2020-11-00; online 2020-03-20]
PubMed DOI Crossref
Cerebrospinal Fluid Levels of Kininogen-1 Indicate Early Cognitive Impairment in Parkinson's Disease.
Markaki I, Bergström S, Tsitsi P, ..., Nilsson P, Svenningsson P
Mov Disord 35 (11) 2101-2106 [2020-11-00; online 2020-08-15]
PubMed DOI Crossref
A freshwater radiation of diplonemids.
Mukherjee I, Salcher MM, Andrei AŞ, ..., Šimek K, Ghai R
Environ. Microbiol. 22 (11) 4658-4668 [2020-11-00; online 2020-09-24]
PubMed DOI Crossref
A comparative genomics multitool for scientific discovery and conservation.
Zoonomia Consortium
Nature 587 (7833) 240-245 [2020-11-00; online 2020-11-11]
DOI Crossref
Drug synergy scoring using minimal dose response matrices
Mäkelä P, Zhang SM, Rudd SG
- - (-) - [2020-10-31; online 2020-10-31]
DOI Crossref
Docking finds GPCR ligands in dark chemical matter
Rudling A, Luttens A, Kihlberg J, ..., Brea J, Zeifman A
- - (-) - [2020-10-31; online 2020-10-31]
Andreas Luttens DDLS Fellow Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Hikarchaeia demonstrate an intermediate stage in the methanogen-to-halophile transition.
Martijn J, Schön ME, Lind AE, ..., Spang A, Ettema TJG
Nat Commun 11 (1) 5490 [2020-10-30; online 2020-10-30]
PubMed DOI Crossref
Potential Anticancer Effect of Carvacrol Codrugs on Human Glioblastoma Cells.
Yazici A, Marinelli L, Cacciatore I, ..., Mardinoğlu A, Türkez H
Curr Drug Deliv 18 (3) 350-356 [2020-10-29; online 2020-10-29]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Genome-Wide Association Study of Metamizole-Induced Agranulocytosis in European Populations.
Cismaru AL, Rudin D, Ibañez L, ..., Wadelius M, Amstutz U
Genes (Basel) 11 (11) - [2020-10-29; online 2020-10-29]
PubMed DOI Crossref
Fluidity and Lipid Composition of Membranes of Peroxisomes, Mitochondria and the ER From Oleic Acid-Induced Saccharomyces cerevisiae.
Reglinski K, Steinfort-Effelsberg L, Sezgin E, ..., Eggeling C, Erdmann R
Front Cell Dev Biol 8 (-) 574363 [2020-10-29; online 2020-10-29]
Erdinc Sezgin SciLifeLab Fellow
DOI Crossref
Fluid Proteomics of CSF and Serum Reveal Important Neuroinflammatory Proteins in Blood-Brain Barrier Disruption and Outcome Prediction Following Severe Traumatic Brain Injury: A Prospective, Observational Study
Lindblad C, Pin E, Just D, ..., Piehl F, Thelin EP
- - (-) - [2020-10-29; online 2020-10-29]
PubMed DOI Crossref
Rapid and cytocompatible cell-laden silk hydrogel formation via riboflavin-mediated crosslinking.
Piluso S, Flores Gomez D, Dokter I, ..., Karperien M, Malda J
J Mater Chem B 8 (41) 9566-9575 [2020-10-28; online 2020-10-02]
PubMed DOI Crossref
Nuclear gene proximity and protein interactions shape transcript covariations in mammalian single cells.
Tarbier M, Mackowiak SD, Frade J, ..., Gallant CJ, Friedländer MR
Nat Commun 11 (1) 5445 [2020-10-28; online 2020-10-28]
DDLS Fellow Magda Bienko Marc Friedländer Marcel Tarbier SciLifeLab Fellow
PubMed DOI Crossref
Microbiomes in a manganese oxide producing ecosystem in the Ytterby mine, Sweden: impact on metal mobility.
Sjöberg S, Stairs CW, Allard B, ..., Ettema TJG, Dupraz C
FEMS Microbiol. Ecol. 96 (11) - [2020-10-28; online 2020-08-21]
DOI Crossref
Integrative transcriptomic analysis of tissue-specific metabolic crosstalk after myocardial infarction
Arif M, Klevstig M, Benfeitas R, ..., Mardinoglu A, Boren J
- - (-) - [2020-10-28; online 2020-10-28]
PubMed DOI Crossref
OGG1 Inhibitor TH5487 Alters OGG1 Chromatin Dynamics and Prevents Incisions.
Hanna BMF, Helleday T, Mortusewicz O
Biomolecules 10 (11) - [2020-10-26; online 2020-10-26]
PubMed DOI Crossref
Hippocampal neural stem cells are more susceptible to the neurotoxin BMAA than primary neurons: effects on apoptosis, cellular differentiation, neurite outgrowth, and DNA methylation.
Pierozan P, Cattani D, Karlsson O
Cell Death Dis 11 (10) 910 [2020-10-24; online 2020-10-24]
Oskar Karlsson SciLifeLab Fellow
DOI Crossref
Bifidobacteria-mediated immune system imprinting early in life
Henrick BM, Rodriguez L, Lakshmikanth T, ..., Frese SA, Brodin P
- - (-) - [2020-10-24; online 2020-10-24]
DOI Crossref
The dynamic transcriptional cell atlas of testis development during human puberty
J G, X N, M G, ..., JM H, BR C
ESPE - (-) - [2020-10-23; online 2020-10-23]
PubMed DOI Crossref
Spatial Transcriptomics Reveals Genes Associated with Dysregulated Mitochondrial Functions and Stress Signaling in Alzheimer Disease.
Navarro JF, Croteau DL, Jurek A, ..., Lundeberg J, Bohr VA
iScience 23 (10) 101556 [2020-10-23; online 2020-09-15]
PubMed DOI Crossref
Single Cell RNA Expression Analysis Using Flow Cytometry Based on Specific Probe Ligation and Rolling Circle Amplification.
Zhao Y, Lin C, Wu P, ..., Nilsson M, Ke R
ACS Sens 5 (10) 3031-3036 [2020-10-23; online 2020-09-24]
PubMed DOI Crossref
Increasing thermal stability and improving biodistribution of VEGFR2-binding affibody molecules by a combination of in silico and directed evolution approaches.
Güler R, Svedmark SF, Abouzayed A, Orlova A, Löfblom J
Sci Rep 10 (1) 18148 [2020-10-23; online 2020-10-23]
PubMed DOI Crossref
Autoantibodies against type I IFNs in patients with life-threatening COVID-19.
Bastard P, Rosen LB, Zhang Q, ..., Su HC, Casanova JL
Science (New York, N.Y.) 370 (6515) - [2020-10-23; online 2020-09-24]
PubMed DOI Crossref
Type III ATP synthase is a symmetry-deviated dimer that induces membrane curvature through tetramerization.
Flygaard RK, Mühleip A, Tobiasson V, Amunts A
Nat Commun 11 (1) 5342 [2020-10-22; online 2020-10-22]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
OmicLoupe: Facilitating biological discovery by interactive exploration of multiple omic datasets and statistical comparisons
Willforss J, Siino V, Levander F
- - (-) - [2020-10-22; online 2020-10-22]
PubMed DOI Crossref
Epigenetic alterations in skin homing CD4+CLA+ T cells of atopic dermatitis patients.
Acevedo N, Benfeitas R, Katayama S, ..., Söderhäll C, Scheynius A
Sci Rep 10 (1) 18020 [2020-10-22; online 2020-10-22]
DOI Crossref
Modelling the dispersion of SARS-CoV-2 on a dynamic network graph
Bryant P, Elofsson A
- - (-) - [2020-10-21; online 2020-10-21]
DDLS Fellow Patrick Bryant
PubMed DOI Crossref
Longitudinal plasma inflammatory proteome profiling during pregnancy in the Born into Life study.
Hedman AM, Lundholm C, Andolf E, ..., Fall T, Almqvist C
Sci Rep 10 (1) 17819 [2020-10-20; online 2020-10-20]
PubMed DOI Crossref
Inhibiting insulin and mTOR signaling by afatinib and crizotinib combination fosters broad cytotoxic effects in cutaneous malignant melanoma.
Das I, Chen H, Maddalo G, ..., Davies MA, Egyházi Brage S
Cell Death Dis 11 (10) 882 [2020-10-20; online 2020-10-20]
PubMed DOI Crossref
Dimerization regulates the human APC/C-associated ubiquitin-conjugating enzyme UBE2S.
Liess AKL, Kucerova A, Schweimer K, ..., Mansfeld J, Lorenz S
Sci Signal 13 (654) - [2020-10-20; online 2020-10-20]
DOI Crossref
Author response: The developmental relationship between teeth and dermal odontodes in the most primitive bony fish Lophosteus
Chen D, Blom H, Sanchez S, ..., Märss T, Ahlberg PE
- - (-) - [2020-10-20; online 2020-10-20]
DOI Crossref
High resolution and high throughput bacteria separation from blood using elasto-inertial microfluidics
Iyengar SN, Kumar T, Mårtensson G, Russom A
- - (-) - [2020-10-19; online 2020-10-19]
DOI Crossref
Estimating divergence times from DNA sequences
Sjödin P, McKenna J, Jakobsson M
- - (-) - [2020-10-19; online 2020-10-19]
PubMed DOI Crossref
Automated identification of the mouse brain's spatial compartments from in situ sequencing data.
Partel G, Hilscher MM, Milli G, ..., Nilsson M, Wählby C
BMC Biol. 18 (1) 144 [2020-10-19; online 2020-10-19]
PubMed DOI Crossref
Secondary ossification center induces and protects growth plate structure.
Xie M, Gol'din P, Herdina AN, ..., Eriksson A, Chagin AS
Elife 9 (-) - [2020-10-16; online 2020-10-16]
PubMed DOI Crossref
Rapid Preparation of a Large Sulfated Metabolite Library for Structure Validation in Human Samples.
Correia MSP, Lin W, Aria AJ, Jain A, Globisch D
Metabolites 10 (10) 415 [2020-10-16; online 2020-10-16]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
Preclinical Evaluation of the GRPR-Targeting Antagonist RM26 Conjugated to the Albumin-Binding Domain for GRPR-Targeting Therapy of Cancer.
Abouzayed A, Tano H, Nagy Á, ..., Eriksson Karlström A, Orlova A
Pharmaceutics 12 (10) - [2020-10-16; online 2020-10-16]
PubMed DOI Crossref
A high-stringency blueprint of the human proteome.
Adhikari S, Nice EC, Deutsch EW, ..., Aebersold R, Baker MS
Nat Commun 11 (1) 5301 [2020-10-16; online 2020-10-16]
PubMed
[11C]5-Hydroxy-tryptophan model for quantitative assessment of in vivo serotonin biosynthesis, retention and degradation in the endocrine pancreas.
Lubberink M, Eriksson O
American journal of nuclear medicine and molecular imaging 10 (5) 226-234 [2020-10-15; online 2020-10-15]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Sub-attomole detection of HIV-1 using padlock probes and rolling circle amplification combined with microfluidic affinity chromatography.
Soares RRG, Varela JC, Neogi U, ..., Madaboosi N, Russom A
Biosens Bioelectron 166 (-) 112442 [2020-10-15; online 2020-07-26]
DOI Crossref
SM-Omics: An automated platform for high-throughput spatial multi-omics
Vickovic S, Lötstedt B, Klughammer J, ..., Rozenblatt-Rosen O, Regev A
- - (-) - [2020-10-15; online 2020-10-15]
Sanja Vickovic SciLifeLab Fellow
PubMed DOI Crossref
From Angiotensin IV to Small Peptidemimetics Inhibiting Insulin-Regulated Aminopeptidase.
Hallberg M, Larhed M
Front. Pharmacol. 11 (-) 590855 [2020-10-15; online 2020-10-15]
PubMed DOI Crossref
Androgen Receptor Signaling Positively Regulates Monocytic Development.
Consiglio CR, Gollnick SO
Front Immunol 11 (-) 519383 [2020-10-15; online 2020-10-15]
Camila Consiglio DDLS Fellow
PubMed DOI Crossref
SARS-CoV-2 (COVID-19) infection in pregnant women: characterization of symptoms and syndromes predictive of disease and severity through real-time, remote participatory epidemiology.
Molteni E, Astley CM, Ma W, ..., Chan AT, Modat M
medRxiv - (-) - [2020-10-14; online 2020-10-14]
PubMed DOI Crossref
Radionuclide Molecular Imaging of EpCAM Expression in Triple-Negative Breast Cancer Using the Scaffold Protein DARPin Ec1.
Vorobyeva A, Bezverkhniaia E, Konovalova E, ..., Deyev S, Tolmachev V
Molecules 25 (20) - [2020-10-14; online 2020-10-14]
PubMed DOI Crossref
Network analysis reveals how lipids and other cofactors influence membrane protein allostery.
Westerlund AM, Fleetwood O, Pérez-Conesa S, Delemotte L
J Chem Phys 153 (14) 141103 [2020-10-14; online 2020-10-23]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Analysis of translating mitoribosome reveals functional characteristics of translation in mitochondria of fungi.
Itoh Y, Naschberger A, Mortezaei N, Herrmann JM, Amunts A
Nat Commun 11 (1) 5187 [2020-10-14; online 2020-10-14]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
A simplified approach to control cell adherence on biologically derived in vitro cell culture scaffolds by direct UV-mediated RGD linkage.
Porras Hernández AM, Pohlit H, Sjögren F, ..., Antfolk M, Tenje M
J Mater Sci Mater Med 31 (10) 89 [2020-10-14; online 2020-10-14]
DOI Crossref
NGSpeciesID: DNA barcode and amplicon consensus generation from long-read sequencing data
Sahlin K, Lim M, Prost S
- - (-) - [2020-10-13; online 2020-10-13]
Kristoffer Sahlin SciLifeLab Fellow
PubMed DOI Crossref
Belowground fungal community diversity, composition and ecological functionality associated with winter wheat in conventional and organic agricultural systems.
Garnica S, Rosenstein R, Schön ME
PeerJ 8 (-) e9732 [2020-10-13; online 2020-10-13]
PubMed DOI Crossref
Vaginal microbiota and human papillomavirus infection among young Swedish women.
Cheng L, Norenhag J, Hu YOO, ..., Engstrand L, Du J
NPJ Biofilms Microbiomes 6 (1) 39 [2020-10-12; online 2020-10-12]
DOI Crossref
Human Developmental Cell Atlas: milestones achieved and the roadmap ahead
Haniffa M, Taylor D, Linnarsson S, ..., Vento-Tormo R, Webb S
- - (-) - [2020-10-12; online 2020-10-12]
PubMed DOI Crossref
TIF-Seq2 disentangles overlapping isoforms in complex human transcriptomes.
Wang J, Li B, Marques S, ..., Wei W, Pelechano V
Nucleic Acids Res. 48 (18) e104 [2020-10-09; online 2020-08-21]
SciLifeLab Fellow Vicente Pelechano
PubMed DOI Crossref
Single-cell and spatial transcriptomics enables probabilistic inference of cell type topography.
Andersson A, Bergenstråhle J, Asp M, ..., Fernández Navarro J, Lundeberg J
Commun Biol 3 (1) 565 [2020-10-09; online 2020-10-09]
PubMed DOI Crossref
Generation and validation of recombinant antibodies to study human aminoacyl-tRNA synthetases.
Preger C, Wigren E, Ossipova E, ..., Gräslund S, Persson H
J Biol Chem 295 (41) 13981-13993 [2020-10-09; online 2020-08-14]
PubMed DOI Crossref
An embryonic stem cell-specific heterochromatin state promotes core histone exchange in the absence of DNA accessibility.
Navarro C, Lyu J, Katsori AM, Caridha R, Elsässer SJ
Nat Commun 11 (1) 5095 [2020-10-09; online 2020-10-09]
SciLifeLab Fellow Simon Elsässer
DOI Crossref
Simulation-guided engineering of antibiotics for improved bacterial uptake
Ferreira RJ, Aguilar V, Villamil Giraldo AM, Kasson PM
- - (-) - [2020-10-08; online 2020-10-08]
PubMed DOI Crossref
SARS-CoV-2 exposure, symptoms and seroprevalence in healthcare workers in Sweden.
Rudberg AS, Havervall S, Månberg A, ..., Hober S, Thålin C
Nat Commun 11 (1) 5064 [2020-10-08; online 2020-10-08]
PubMed DOI Crossref
Temporal changes in the vaginal microbiota in self-samples and its association with persistent HPV16 infection and CIN2.
Berggrund M, Gustavsson I, Aarnio R, ..., Olovsson M, Gyllensten U
Virol. J. 17 (1) 147 [2020-10-07; online 2020-10-07]
PubMed DOI Crossref
Receptor occupancy of dual glucagon-like peptide 1/glucagon receptor agonist SAR425899 in individuals with type 2 diabetes.
Eriksson O, Haack T, Hijazi Y, ..., Wagner M, Tillner J
Sci Rep 10 (1) 16758 [2020-10-07; online 2020-10-07]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Heterogeneous parallelization and acceleration of molecular dynamics simulations in GROMACS.
Páll S, Zhmurov A, Bauer P, ..., Hess B, Lindahl E
J Chem Phys 153 (13) 134110 [2020-10-07; online 2020-10-10]
PubMed DOI Crossref
Endothelial-Tumor Cell Interaction in Brain and CNS Malignancies.
Peleli M, Moustakas A, Papapetropoulos A
Int J Mol Sci 21 (19) - [2020-10-06; online 2020-10-06]
PubMed DOI Crossref
Deconstructing tumor heterogeneity: the stromal perspective.
Vickman RE, Faget DV, Beachy P, ..., Hayward SW, Stewart SA
Oncotarget 11 (40) 3621-3632 [2020-10-06; online 2020-10-06]
PubMed DOI Crossref
Cascading effects in freshwater microbial food webs by predatory Cercozoa, Katablepharidacea and ciliates feeding on aplastidic bacterivorous cryptophytes.
Šimek K, Grujčić V, Mukherjee I, ..., Mehrshad M, Salcher MM
FEMS Microbiol. Ecol. 96 (10) - [2020-10-06; online 2020-06-20]
DOI Crossref
An artificial neural network approach integrating plasma proteomics and genetic data identifies PLXNA4 as a new susceptibility locus for pulmonary embolism
Razzaq M, Iglesias MJ, Ibrahim-Kosta M, ..., Morange PE, Trégouët DA
- - (-) - [2020-10-06; online 2020-10-06]
PubMed DOI Crossref
Pre-extinction Demographic Stability and Genomic Signatures of Adaptation in the Woolly Rhinoceros.
Lord E, Dussex N, Kierczak M, ..., Götherström A, Dalén L
Curr. Biol. 30 (19) 3871-3879.e7 [2020-10-05; online 2020-08-13]
PubMed DOI Crossref
Non-targeted urine metabolomics and associations with prevalent and incident type 2 diabetes.
Salihovic S, Broeckling CD, Ganna A, ..., Ärnlöv J, Nowak C
Sci Rep 10 (1) 16474 [2020-10-05; online 2020-10-05]
PubMed DOI Crossref
HEARTBREAK Controls Post-translational Modification of INDEHISCENT to Regulate Fruit Morphology in Capsella.
Dong Y, Majda M, Šimura J, ..., Smith RS, Østergaard L
Curr. Biol. 30 (19) 3880-3888.e5 [2020-10-05; online 2020-08-13]
SciLifeLab Fellow Tanja Slotte
DOI Crossref
Combined Metabolic Activators accelerates recovery in mild-to-moderate COVID-19
Altay O, Arif M, Li X, ..., Uhlén M, Mardinoglu A
medRxiv - (-) - [2020-10-05; online 2020-10-05]
Adil Mardinoglu DDLS Fellow Muhammad Arif Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Modulating pyrimidine ribonucleotide levels for the treatment of cancer.
Mollick T, Laín S
Cancer Metab 8 (-) 12 [2020-10-04; online 2020-10-04]
PubMed DOI Crossref
The Synapse Diversity Dilemma: Molecular Heterogeneity Confounds Studies of Synapse Function.
Grant SGN, Fransén E
Front Synaptic Neurosci 12 (-) 590403 [2020-10-02; online 2020-10-02]
DOI Crossref
Parallelized calculation of permutation tests
Ekvall M, Höhle M, Käll L
- - (-) - [2020-10-02; online 2020-10-02]
PubMed DOI Crossref
A latent lineage potential in resident neural stem cells enables spinal cord repair.
Llorens-Bobadilla E, Chell JM, Le Merre P, ..., Carlén M, Frisén J
Science (New York, N.Y.) 370 (6512) - [2020-10-02; online 2020-10-03]
PubMed DOI Crossref
Khoe-San Genomes Reveal Unique Variation and Confirm the Deepest Population Divergence in Homo sapiens.
Schlebusch CM, Sjödin P, Breton G, ..., Soodyall H, Jakobsson M
Mol. Biol. Evol. 37 (10) 2944-2954 [2020-10-01; online 2020-07-23]
PubMed DOI Crossref
Flash X-ray diffraction imaging in 3D: a proposed analysis pipeline.
Liu J, Engblom S, Nettelblad C
J Opt Soc Am A Opt Image Sci Vis 37 (10) 1673-1686 [2020-10-01; online 2020-10-27]
PubMed DOI Crossref
External Evaluation of 3 Commercial Artificial Intelligence Algorithms for Independent Assessment of Screening Mammograms.
Salim M, Wåhlin E, Dembrower K, ..., Eklund M, Strand F
JAMA Oncol 6 (10) 1581-1588 [2020-10-01; online 2020-08-28]
PubMed DOI Crossref
Defining the clinical, molecular and imaging spectrum of adaptor protein complex 4-associated hereditary spastic paraplegia.
Ebrahimi-Fakhari D, Teinert J, Behne R, ..., Bennett JT, Sahin M
Brain 143 (10) 2929-2944 [2020-10-01; online 2020-09-27]
PubMed DOI Crossref
Brain Transcriptomics of Wild and Domestic Rabbits Suggests That Changes in Dopamine Signaling and Ciliary Function Contributed to Evolution of Tameness.
Sato DX, Rafati N, Ring H, ..., Carneiro M, Andersson L
Genome Biol Evol 12 (10) 1918-1928 [2020-10-01; online 2020-08-25]
PubMed DOI Crossref
What do tropical cryptogams reveal? Strong genetic structure in Amazonian bryophytes.
Ledent A, Gauthier J, Pereira M, ..., Zartman CE, Vanderpoorten A
New Phytol. 228 (2) 640-650 [2020-10-00; online 2020-07-06]
PubMed DOI Crossref
Unraveling the Immune Response in Severe COVID-19.
Rodriguez L, Brodin P
J Clin Immunol 40 (7) 958-959 [2020-10-00; online 2020-08-22]
DOI Crossref
Ultra-Fast Clearing Protocol for 3D Optical Renal Pathology
Unnersjö-Jess D, Butt L, Höhne M, ..., Brismar H, Blom H
J. Am. Soc. Nephrol. 31 (10S) 680-680 [2020-10-00; online 2020-10-00]
DOI Crossref
The integrated stress response exposes a therapeutic vulnerability in KRAS driven lung cancer
Ghaddar N, Wang S, Woodvine B, ..., Le Quesne J, Koromilas A
Eur. J. Cancer 138 (-) S23 [2020-10-00; online 2020-10-00]
PubMed DOI Crossref
The adaptive potential of circular DNA accumulation in ageing cells.
Hull RM, Houseley J
Curr. Genet. 66 (5) 889-894 [2020-10-00; online 2020-04-15]
PubMed DOI Crossref
Ten simple rules for annotating sequencing experiments.
Stevens I, Mukarram AK, Hörtenhuber M, ..., Rung J, Daub CO
PLoS Comput Biol 16 (10) e1008260 [2020-10-00; online 2020-10-05]
PubMed DOI Crossref
Spatially Resolved Transcriptomes-Next Generation Tools for Tissue Exploration.
Asp M, Bergenstråhle J, Lundeberg J
Bioessays 42 (10) e1900221 [2020-10-00; online 2020-05-04]
DOI Crossref
Segmental Expression of Nephrin in the Slit Diaphragm of a Patient with a Nonsense Mutation in NPHS1
Unnersjö-Jess D, Butt L, Hieronymi L, ..., Schermer B, Benzing T
J. Am. Soc. Nephrol. 31 (10S) 524-524 [2020-10-00; online 2020-10-00]
PubMed DOI Crossref
SPANX Control of Lamin A/C Modulates Nuclear Architecture and Promotes Melanoma Growth.
Lazar I, Fabre B, Feng Y, ..., Dummer R, Ronai ZA
Mol. Cancer Res. 18 (10) 1560-1573 [2020-10-00; online 2020-06-22]
PubMed DOI Crossref
Progesterone - Friend or foe?
Sundström-Poromaa I, Comasco E, Sumner R, Luders E
Front Neuroendocrinol 59 (-) 100856 [2020-10-00; online 2020-07-28]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Profiles of histidine-rich glycoprotein associate with age and risk of all-cause mortality.
Hong MG, Dodig-Crnković T, Chen X, ..., Magnusson PK, Schwenk JM
Life Sci. Alliance 3 (10) - [2020-10-00; online 2020-07-31]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
Ouabain Modulates the Functional Interaction Between Na,K-ATPase and NMDA Receptor.
Akkuratov EE, Westin L, Vazquez-Juarez E, ..., Brismar H, Aperia A
Mol. Neurobiol. 57 (10) 4018-4030 [2020-10-00; online 2020-07-10]
DOI Crossref
OC03.02: *Ultrasound image analysis using deep neural networks to discriminate benign and malignant ovarian tumours: a comparison to subjective expert assessment
Christiansen F, Epstein E, Smedberg E, ..., Smith K, Epstein E
Ultrasound in Obstet & Gyne 56 (S1) 8-8 [2020-10-00; online 2020-10-15]
PubMed DOI Crossref
Metagenomic analysis of bacteria in stallion semen.
Al-Kass Z, Guo Y, Vinnere Pettersson O, Niazi A, Morrell JM
Anim Reprod Sci 221 (-) 106568 [2020-10-00; online 2020-08-01]
PubMed DOI Crossref
Male swarming aggregation pheromones increase female attraction and mating success among multiple African malaria vector mosquito species.
Mozūraitis R, Hajkazemian M, Zawada JW, ..., Borg-Karlson AK, Emami SN
Nat Ecol Evol 4 (10) 1395-1401 [2020-10-00; online 2020-08-03]
Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
KIT pathway upregulation predicts dasatinib efficacy in acute myeloid leukemia.
Malani D, Yadav B, Kumar A, ..., Murumägi A, Kallioniemi O
Leukemia 34 (10) 2780-2784 [2020-10-00; online 2020-07-17]
PubMed DOI Crossref
Inferring tumor progression in large datasets.
Mohaghegh Neyshabouri M, Jun SH, Lagergren J
PLoS Comput Biol 16 (10) e1008183 [2020-10-00; online 2020-10-09]
DOI Crossref
In Situ Microfluidic Preparation and Solidification of Alginate Microgels
Damiati S
Macromol. Res. 28 (11) 1046-1053 [2020-10-00; online 2020-08-18]
PubMed DOI Crossref
Immunogenetics in systemic lupus erythematosus: Transitioning from genetic associations to cellular effects.
Hagberg N, Lundtoft C, Rönnblom L
Scand. J. Immunol. 92 (4) e12894 [2020-10-00; online 2020-05-20]
PubMed DOI Crossref
Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals.
Folkersen L, Gustafsson S, Wang Q, ..., Ingelsson E, Mälarstig A
Nat Metab 2 (10) 1135-1148 [2020-10-00; online 2020-10-16]
PubMed DOI Crossref
GPSeq reveals the radial organization of chromatin in the cell nucleus.
Girelli G, Custodio J, Kallas T, ..., Crosetto N, Bienko M
Nat. Biotechnol. 38 (10) 1184-1193 [2020-10-00; online 2020-05-25]
Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
Function of multiple sclerosis-protective HLA class I alleles revealed by genome-wide protein-quantitative trait loci mapping of interferon signalling.
Lundtoft C, Pucholt P, Imgenberg-Kreuz J, ..., Rönnblom L, Hagberg N
PLoS Genet 16 (10) e1009199 [2020-10-00; online 2020-10-26]
PubMed DOI Crossref
Exploratory analysis of circulating cytokines in patients with metastatic breast cancer treated with eribulin: the TRANSERI-GONO (Gruppo Oncologico del Nord Ovest) study.
Garrone O, Michelotti A, Paccagnella M, ..., Di Maio M, Merlano M
ESMO Open 5 (5) e000876 [2020-10-00; online 2020-10-15]
PubMed DOI Crossref
European practice patterns and barriers to smoking cessation after a cancer diagnosis in the setting of curative versus palliative cancer treatment.
Derksen JWG, Warren GW, Jordan K, ..., Koopman M, May AM
Eur. J. Cancer 138 (-) 99-108 [2020-10-00; online 2020-08-29]
PubMed DOI Crossref
Emerging Importance of Survivin in Stem Cells and Cancer: the Development of New Cancer Therapeutics.
Warrier NM, Agarwal P, Kumar P
Stem Cell Rev Rep 16 (5) 828-852 [2020-10-00; online 2020-07-22]
PubMed DOI Crossref
Differences in structure and hibernation mechanism highlight diversification of the microsporidian ribosome.
Ehrenbolger K, Jespersen N, Sharma H, ..., Vossbrinck CR, Barandun J
PLoS Biol. 18 (10) e3000958 [2020-10-00; online 2020-10-30]
Jonas Barandun SciLifeLab Fellow
PubMed DOI Crossref
Development of a chemical probe against NUDT15.
Zhang SM, Desroses M, Hagenkort A, ..., Stenmark P, Helleday T
Nat. Chem. Biol. 16 (10) 1120-1128 [2020-10-00; online 2020-07-20]
DOI Crossref
DNA metabarcoding reveals microbial community dynamics in a microalgae-based municipal wastewater treatment open photobioreactor
Ferro L, Hu YOO, Gentili FG, Andersson AF, Funk C
Algal Research 51 (-) 102043 [2020-10-00; online 2020-10-00]
PubMed DOI Crossref
Cotranslational folding of alkaline phosphatase in the periplasm of Escherichia coli.
Elfageih R, Karyolaimos A, Kemp G, ..., von Heijne G, Kudva R
Protein Sci. 29 (10) 2028-2037 [2020-10-00; online 2020-08-24]
PubMed DOI Crossref
Compared with matched controls, patients with postoperative atrial fibrillation (POAF) have increased long-term AF after CABG, and POAF is further associated with increased ischemic stroke, heart failure and mortality even after adjustment for AF.
Thorén E, Wernroth ML, Christersson C, ..., Jidéus L, Ståhle E
Clin Res Cardiol 109 (10) 1232-1242 [2020-10-00; online 2020-02-08]
PubMed DOI Crossref
Clonal hematopoiesis in patients with high-grade B-cell lymphoma is associated with inferior outcome.
Amini RM, Ljungström V, Abdulla M, ..., Enblad G, Baliakas P
Am. J. Hematol. 95 (10) E287-E289 [2020-10-00; online 2020-08-12]
PubMed DOI Crossref
Characterization of anti-BCG benz[α]anthraquinones and new siderophores from a Xinjiang desert-isolated rare actinomycete Nocardia sp. XJ31.
Zhang L, Zhang J, Ren B, ..., Zhang L, Liu X
Appl. Microbiol. Biotechnol. 104 (19) 8267-8278 [2020-10-00; online 2020-08-24]
PubMed DOI Crossref
Body composition after allogeneic haematopoietic cell transplantation/total body irradiation in children and young people: a restricted systematic review.
Lorenc A, Hamilton-Shield J, Perry R, Stevens M, CTYA HSCT Adipose and Muscle Late Effects Working Group
J Cancer Surviv 14 (5) 624-642 [2020-10-00; online 2020-07-18]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Association of serum anti-centromere protein F antibodies with clinical response to infliximab in patients with rheumatoid arthritis: A prospective study.
Lourido L, Ruiz-Romero C, Picchi F, ..., Nilsson P, Blanco FJ
Semin Arthritis Rheum 50 (5) 1101-1108 [2020-10-00; online 2020-06-30]
PubMed DOI Crossref
Assigned NMR backbone resonances of the ligand-binding region domain of the pneumococcal serine-rich repeat protein (PsrP-BR) reveal a rigid monomer in solution.
Schulte T, Sala BM, Nilvebrant J, ..., Agback T, Agback P
Biomol NMR Assign 14 (2) 195-200 [2020-10-00; online 2020-04-20]
PubMed DOI Crossref
Antibiotic use and the risk of breast cancer: A systematic review and dose-response meta-analysis.
Simin J, Tamimi RM, Engstrand L, Callens S, Brusselaers N
Pharmacol Res 160 (-) 105072 [2020-10-00; online 2020-07-15]
PubMed DOI Crossref
Aberrantly elevated suprabasin in the bone marrow as a candidate biomarker of advanced disease state in myelodysplastic syndromes.
Pribyl M, Hubackova S, Moudra A, ..., Bartek J, Hodny Z
Mol Oncol 14 (10) 2403-2419 [2020-10-00; online 2020-08-11]
PubMed DOI Crossref
ANHIR: Automatic Non-Rigid Histological Image Registration Challenge.
Borovec J, Kybic J, Arganda-Carreras I, ..., Zhao S, Munoz-Barrutia A
IEEE Trans Med Imaging 39 (10) 3042-3052 [2020-10-00; online 2020-04-07]
DDLS Fellow Kimmo Kartasalo
PubMed DOI Crossref
Retraction: Andersen S. S. L. Real time large scale in vivo observations reveal intrinsic synchrony, plasticity and growth cone dynamics of midline crossing axons at the ventral floor plate of the zebrafish spinal cord. J. Integr. Neurosci. 18(4), 351-368.
Andersen SSL
J Integr Neurosci 19 (3) 593 [2020-09-30; online 2020-10-20]
PubMed DOI Crossref
High-fat diet and estrogen impacts the colon and its transcriptome in a sex-dependent manner.
Hases L, Archer A, Indukuri R, ..., Korach-André M, Williams C
Sci Rep 10 (1) 16160 [2020-09-30; online 2020-09-30]
PubMed DOI Crossref
Streamlined and Abundant Bacterioplankton Thrive in Functional Cohorts.
Mondav R, Bertilsson S, Buck M, ..., Lindström ES, Garcia SL
mSystems 5 (5) - [2020-09-29; online 2020-09-29]
Sarahi Garcia SciLifeLab Fellow
PubMed DOI Crossref
Reconstruction of the birth of a male sex chromosome present in Atlantic herring.
Rafati N, Chen J, Herpin A, ..., Schartl M, Andersson L
Proc. Natl. Acad. Sci. U.S.A. 117 (39) 24359-24368 [2020-09-29; online 2020-09-16]
DOI Crossref
Residue-by-residue analysis of cotranslational membrane protein integration in vivo
Nicolaus F, Metola A, Mermans D, ..., Miller TF, von Heijne G
- - (-) - [2020-09-28; online 2020-09-28]
DOI Crossref
Transposon- and genome dynamics in the fungal genus Neurospora : insights from nearly gapless genome assemblies
Nguyen D, Peona V, Unneberg P, ..., Jern P, Johannesson H
- - (-) - [2020-09-27; online 2020-09-27]
DOI Crossref
Genomics of an avian neo-sex chromosome reveals the evolutionary dynamics of recombination suppression and sex-linked genes
Sigeman H, Strandh M, Proux-Wéra E, ..., Westerdahl H, Hansson B
- - (-) - [2020-09-26; online 2020-09-26]
PubMed DOI Crossref
Smad7 Enhances TGF-β-Induced Transcription of c-Jun and HDAC6 Promoting Invasion of Prostate Cancer Cells.
Thakur N, Hamidi A, Song J, ..., Heldin CH, Landström M
iScience 23 (9) 101470 [2020-09-25; online 2020-09-03]
DOI Crossref
Integrating identification and quantification uncertainty for differential protein abundance analysis with Triqler
The M, Käll L
- - (-) - [2020-09-25; online 2020-09-25]
PubMed DOI Crossref
High throughput generation of a resource of the human secretome in mammalian cells.
Tegel H, Dannemeyer M, Kanje S, ..., Uhlén M, Hober S
N Biotechnol 58 (-) 45-54 [2020-09-25; online 2020-06-02]
DDLS Fellow Fredrik Edfors
DOI Crossref
Effect of molecular phenotype based on Warburg effect pathway on the prognosis and the efficacy of postoperative radiation in cervical cancer
Li N, Xu H, Sun X, ..., Zhou Y, Zhou F
Chinese Journal of Radiological Medicine and Protection 40 (9) 666-673 [2020-09-25]
DDLS Fellow Qiaoli Wang
PubMed DOI Crossref
High-Resolution Imaging of Tumor Spheroids and Organoids Enabled by Expansion Microscopy.
Edwards SJ, Carannante V, Kuhnigk K, ..., Önfelt B, Brismar H
Front Mol Biosci 7 (-) 208 [2020-09-24; online 2020-09-24]
PubMed DOI Crossref
Discovery of Proteolysis-Targeting Chimera Molecules that Selectively Degrade the IRAK3 Pseudokinase.
Degorce SL, Tavana O, Banks E, ..., Yang B, Edmondson SD
J Med Chem 63 (18) 10460-10473 [2020-09-24; online 2020-09-14]
SciLifeLab Fellow Yumeng Mao
PubMed DOI Crossref
Basal Ganglia-A Motion Perspective.
Grillner S, Robertson B, Kotaleski JH
Compr Physiol 10 (4) 1241-1275 [2020-09-24; online 2020-09-24]
DOI Crossref
Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation
Mahajan A, Spracklen CN, Zhang W, ..., McCarthy MI, Morris AP
- - (-) - [2020-09-23; online 2020-09-23]
PubMed DOI Crossref
Massive and rapid COVID-19 testing is feasible by extraction-free SARS-CoV-2 RT-PCR.
Smyrlaki I, Ekman M, Lentini A, ..., Högberg B, Reinius B
Nat Commun 11 (1) 4812 [2020-09-23; online 2020-09-23]
Antonio Lentini DDLS Fellow
PubMed DOI Crossref
Glucocorticoids induce differentiation and chemoresistance in ovarian cancer by promoting ROR1-mediated stemness.
Karvonen H, Arjama M, Kaleva L, ..., Murumägi A, Ungureanu D
Cell Death Dis 11 (9) 790 [2020-09-23; online 2020-09-23]
DOI Crossref
Single-cell multimodal omics and directly reprogrammed neurons to probe reduced penetrance in Frontotemporal Dementia
Natarajan K, Eisfeldt J, Hammond M, ..., Parmar M, Graff C
- - (-) - [2020-09-22; online 2020-09-22]
PubMed DOI Crossref
No Assembly Required: Using BTyper3 to Assess the Congruency of a Proposed Taxonomic Framework for the Bacillus cereus Group With Historical Typing Methods.
Carroll LM, Cheng RA, Kovac J
Front Microbiol 11 (-) 580691 [2020-09-22; online 2020-09-22]
DDLS Fellow Laura Carroll
PubMed DOI Crossref
Deltaproteobacteria and Spirochaetes-Like Bacteria Are Abundant Putative Mercury Methylators in Oxygen-Deficient Water and Marine Particles in the Baltic Sea.
Capo E, Bravo AG, Soerensen AL, ..., Buck M, Björn E
Front Microbiol 11 (-) 574080 [2020-09-22; online 2020-09-22]
PubMed DOI Crossref
Complement Properdin Regulates the Metabolo-Inflammatory Response to a High Fat Diet.
Thomas RC, Kheder R, Alaridhee H, Martin N, Stover CM
Medicina (Kaunas) 56 (9) - [2020-09-22; online 2020-09-22]
PubMed DOI Crossref
Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples.
Bailey MH, Meyerson WU, Dursi LJ, ..., Ding L, PCAWG Consortium
Nat Commun 11 (1) 4748 [2020-09-21; online 2020-09-21]
PubMed DOI Crossref
Applications of Genome-Wide Screening and Systems Biology Approaches in Drug Repositioning.
Mohammadi E, Benfeitas R, Turkez H, ..., Uhlen M, Mardinoglu A
Cancers (Basel) 12 (9) - [2020-09-21; online 2020-09-21]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Chromogranin A regulates gut permeability via the antagonistic actions of its proteolytic peptides
Muntjewerff EM, Tang K, Lutter L, ..., van den Bogaart G, Mahata SK
- - (-) - [2020-09-20; online 2020-09-20]
Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
FRET-Based Sorting of Live Cells Reveals Shifted Balance between PLK1 and CDK1 Activities During Checkpoint Recovery.
Lafranchi L, Müllers E, Rutishauser D, Lindqvist A
Cells 9 (9) - [2020-09-19; online 2020-09-19]
PubMed DOI Crossref
SPT6-driven error-free DNA repair safeguards genomic stability of glioblastoma cancer stem-like cells.
Obara EAA, Aguilar-Morante D, Rasmussen RD, ..., Bartek J, Hamerlik P
Nat Commun 11 (1) 4709 [2020-09-18; online 2020-09-18]
DOI Crossref
Multiple introgressions shape mitochondrial evolutionary history in Drosophila paulistorum and the Drosophila willistoni group
Baião GC, Schneider DI, Miller WJ, Klasson L
- - (-) - [2020-09-18; online 2020-09-18]
DOI Crossref
Antibodies to SARS-CoV-2 and risk of future sickness
Dillner J, Elfström KM, Blomqvist J, ..., Mühr LSA, Lundgren KC
- - (-) - [2020-09-18; online 2020-09-18]
DOI Crossref
Respiration rates of herring larvae at different salinities, and effects of previous environmental history
Berg F, Andersson L, Folkvord A
Mar. Ecol. Prog. Ser. 650 (-) 141-152 [2020-09-17; online 2020-09-17]
PubMed DOI Crossref
Northstar enables automatic classification of known and novel cell types from tumor samples.
Zanini F, Berghuis BA, Jones RC, ..., Clarke MF, Quake SR
Sci Rep 10 (1) 15251 [2020-09-17; online 2020-09-17]
PubMed DOI Crossref
Characterization of zika virus infection of human fetal cardiac mesenchymal stromal cells.
Rossi F, Josey B, Sayitoglu EC, ..., Duru AD, Beljanski V
PLoS ONE 15 (9) e0239238 [2020-09-17; online 2020-09-17]
DOI Crossref
Transcriptome analysis of EPO and GFP HEK293 Cell-lines Reveal Shifts in Energy and ER Capacity Support Improved Erythropoietin Production in HEK293F Cells
Saghaleyni R, Malm M, Zrimec J, ..., Robinson JL, Rockberg J
- - (-) - [2020-09-16; online 2020-09-16]
Aleksej Zelezniak SciLifeLab Fellow
PubMed DOI Crossref
Arrangement and symmetry of the fungal E3BP-containing core of the pyruvate dehydrogenase complex.
Forsberg BO, Aibara S, Howard RJ, Mortezaei N, Lindahl E
Nat Commun 11 (1) 4667 [2020-09-16; online 2020-09-16]
Björn Forsberg DDLS Fellow
PubMed DOI Crossref
Genome-Wide CRISPR Off-Target DNA Break Detection by the BLISS Method.
Ballarino R, Bouwman BAM, Crosetto N
Methods in molecular biology (Clifton, N.J.) 2162 (-) 261-281 [2020-09-15; online 2020-09-15]
PubMed DOI Crossref
Estimating the impact of mobility patterns on COVID-19 infection rates in 11 European countries.
Bryant P, Elofsson A
PeerJ 8 (-) e9879 [2020-09-15; online 2020-09-15]
DDLS Fellow Patrick Bryant
DOI Crossref
Rapid development of cloud-native intelligent data pipelines for scientific data streams using the HASTE Toolkit
Blamey B, Toor S, Dahlö M, ..., Spjuth O, Hellander A
- - (-) - [2020-09-14; online 2020-09-14]
DOI Crossref
COVID-19 and beyond: a call for action and audacious solidarity to all the citizens and nations, it is humanity’s fight
Auffray C, Balling R, Blomberg N, ..., Wolkenhauer O, Wouters E
F1000Res 9 (-) 1130 [2020-09-14; online 2020-09-14]
PubMed DOI Crossref
The Novel Anti-cMet Antibody seeMet 12 Potentiates Sorafenib Therapy and Radiotherapy in a Colorectal Cancer Model.
Spiegelberg D, Mortensen ACL, Palupi KD, ..., Lane DP, Nestor M
Front Oncol 10 (-) 1717 [2020-09-11; online 2020-09-11]
DOI Crossref
Freshwater Chlorobia exhibit metabolic specialization among cosmopolitan and endemic populations
Garcia SL, Mehrshad M, Buck M, ..., Greening C, Peura S
- - (-) - [2020-09-11; online 2020-09-11]
Sarahi Garcia Sari Peura SciLifeLab Fellow
PubMed DOI Crossref
Compositional and functional differences of the mucosal microbiota along the intestine of healthy individuals.
Vaga S, Lee S, Ji B, ..., Engstrand L, Shoaie S
Sci Rep 10 (1) 14977 [2020-09-11; online 2020-09-11]
Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
A whole-genome sequenced control population in northern Sweden reveals subregional genetic differences.
Svensson D, Rentoft M, Dahlin AM, ..., Trygg J, Johansson E
PLoS ONE 15 (9) e0237721 [2020-09-11; online 2020-09-11]
DOI Crossref
Machine learning-based investigation of the cancer protein secretory pathway
Saghaleyni R, Muhammad AS, Bangalore P, Nielsen J, Robinson JL
- - (-) - [2020-09-10; online 2020-09-10]
PubMed DOI Crossref
Disease, Drugs and Dysbiosis: Understanding Microbial Signatures in Metabolic Disease and Medical Interventions.
Proffitt C, Bidkhori G, Moyes D, Shoaie S
Microorganisms 8 (9) 1381 [2020-09-09; online 2020-09-09]
Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Integration of molecular profiles in a longitudinal wellness profiling cohort.
Tebani A, Gummesson A, Zhong W, ..., Uhlen M, Fagerberg L
Nat Commun 11 (1) 4487 [2020-09-08; online 2020-09-08]
Adil Mardinoglu DDLS Fellow Fredrik Edfors Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
How cholesterol stiffens unsaturated lipid membranes.
Chakraborty S, Doktorova M, Molugu TR, ..., Brown MF, Ashkar R
Proc. Natl. Acad. Sci. U.S.A. 117 (36) 21896-21905 [2020-09-08; online 2020-08-25]
DDLS Fellow Milka Doktorova
PubMed DOI Crossref
Broad host range of SARS-CoV-2 predicted by comparative and structural analysis of ACE2 in vertebrates.
Damas J, Hughes GM, Keough KC, ..., Karlsson EK, Lewin HA
Proc. Natl. Acad. Sci. U.S.A. 117 (36) 22311-22322 [2020-09-08; online 2020-08-21]
DOI Crossref
Leaky Severe Combined Immunodeficiency in Mice Lacking Non-homologous End Joining Factors XLF and MRI
Castaneda-Zegarra S, Zhang Q, Alirezaylavasani A, ..., Yao R, Oksenych V
- - (-) - [2020-09-06; online 2020-09-06]
PubMed DOI Crossref
The RNA exosome shapes the expression of key protein-coding genes.
Wu M, Karadoulama E, Lloret-Llinares M, ..., Jensen TH, Sandelin A
Nucleic Acids Res. 48 (15) 8509-8528 [2020-09-04; online 2020-07-28]
SciLifeLab Fellow
PubMed DOI Crossref
Genome sequence of segmented filamentous bacteria present in the human intestine.
Jonsson H, Hugerth LW, Sundh J, Lundin E, Andersson AF
Commun Biol 3 (1) 485 [2020-09-04; online 2020-09-04]
DDLS Fellow Luisa Hugerth
DOI Crossref
Author response: Secondary ossification center induces and protects growth plate structure
Xie M, Gol'din P, Herdina AN, ..., Eriksson A, Chagin AS
- - (-) - [2020-09-04; online 2020-09-04]
PubMed DOI Crossref
An alpaca nanobody neutralizes SARS-CoV-2 by blocking receptor interaction.
Hanke L, Vidakovics Perez L, Sheward DJ, ..., Murrell B, McInerney GM
Nat Commun 11 (1) 4420 [2020-09-04; online 2020-09-04]
DOI Crossref
Hybrid seed incompatibility in Capsella is connected to chromatin condensation defects in the endosperm
Dziasek K, Simon L, Placette CL, ..., Slotte T, Köhler C
- - (-) - [2020-09-03; online 2020-09-03]
SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Bilayer-Coated Nanoparticles Reveal How Influenza Viral Entry Depends on Membrane Deformability but Not Curvature.
Villamil Giraldo AM, Kasson PM
J Phys Chem Lett 11 (17) 7190-7196 [2020-09-03; online 2020-08-19]
DOI Crossref
Accurate spliced alignment of long RNA sequencing reads
Sahlin K, Mäkinen V
bioRxiv - (-) - [2020-09-03; online 2020-09-03]
Kristoffer Sahlin SciLifeLab Fellow
PubMed DOI Crossref
Twentieth-century emergence of antimicrobial resistant human- and bovine-associated Salmonella enterica serotype Typhimurium lineages in New York State.
Carroll LM, Huisman JS, Wiedmann M
Sci Rep 10 (1) 14428 [2020-09-02; online 2020-09-02]
DDLS Fellow Laura Carroll
PubMed DOI Crossref
Mutations Upstream of the TBX5 and PITX1 Transcription Factor Genes Are Associated with Feathered Legs in the Domestic Chicken.
Li J, Lee M, Davis BW, ..., Siegel PB, Andersson L
Mol. Biol. Evol. 37 (9) 2477-2486 [2020-09-01; online 2020-04-29]
PubMed DOI Crossref
MTH1 Inhibitor TH588 Disturbs Mitotic Progression and Induces Mitosis-Dependent Accumulation of Genomic 8-oxodG.
Rudd SG, Gad H, Sanjiv K, ..., Berglund UW, Helleday T
Cancer Res. 80 (17) 3530-3541 [2020-09-01; online 2020-04-20]
PubMed DOI Crossref
Evolutionary Remodeling of the Cell Envelope in Bacteria of the Planctomycetes Phylum.
Mahajan M, Seeger C, Yee B, Andersson SGE
Genome Biol Evol 12 (9) 1528-1548 [2020-09-01; online 2020-08-08]
PubMed DOI Crossref
Corrigendum to "Monoamine oxidase A genotype and methylation moderate the association of maltreatment and aggressive behaviour" [Behav. Brain Res. 382 (2020) 112476].
Checknita D, Bendre M, Ekström TJ, ..., Hodgins S, Nilsson KW
Behav. Brain Res. 393 (-) 112721 [2020-09-01; online 2020-06-23]
Erika Comasco SciLifeLab Fellow
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Xdrop: Targeted sequencing of long DNA molecules from low input samples using droplet sorting.
Madsen EB, Höijer I, Kvist T, Ameur A, Mikkelsen MJ
Hum. Mutat. 41 (9) 1671-1679 [2020-09-00; online 2020-06-29]
PubMed DOI Crossref
Transglutaminase 1 and 2 are localized in different blood cells in the freshwater crayfish Pacifastacus leniusculus.
Junkunlo K, Söderhäll K, Söderhäll I
Fish Shellfish Immunol. 104 (-) 83-91 [2020-09-00; online 2020-05-30]
PubMed DOI Crossref
To inhibit TrxR1 is to inactivate STAT3-Inhibition of TrxR1 enzymatic function by STAT3 small molecule inhibitors.
Busker S, Page B, Arnér ESJ
Redox Biol 36 (-) 101646 [2020-09-00; online 2020-07-17]
PubMed DOI Crossref
The past and future human impact on mammalian diversity.
Andermann T, Faurby S, Turvey ST, Antonelli A, Silvestro D
Sci Adv 6 (36) - [2020-09-00; online 2020-09-04]
DDLS Fellow Tobias Andermann
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Sholl LM, Hirsch FR, Hwang D, ..., Kerr KM, Longshore JW
J Thorac Oncol 15 (9) 1409-1424 [2020-09-00; online 2020-06-06]
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Systems Biology: A Multi-Omics Integration Approach to Metabolism and the Microbiome.
Son JW, Shoaie S, Lee S
Endocrinol Metab (Seoul) 35 (3) 507-514 [2020-09-00; online 2020-09-22]
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DOI Crossref
Steady moving contact line of water over a no-slip substrate
Lācis U, Johansson P, Fullana T, ..., Bagheri S, Zaleski S
Eur. Phys. J. Spec. Top. 229 (10) 1897-1921 [2020-09-00; online 2020-09-14]
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Similar names, different results: Consistency of the associations between prenatal exposure to phthalates and parent-ratings of behavior problems in preschool children.
England-Mason G, Martin JW, MacDonald A, ..., Letourneau N, Dewey D
Environ Int 142 (-) 105892 [2020-09-00; online 2020-06-25]
PubMed DOI Crossref
Shared structural mechanisms of general anaesthetics and benzodiazepines.
Kim JJ, Gharpure A, Teng J, ..., Lindahl E, Hibbs RE
Nature 585 (7824) 303-308 [2020-09-00; online 2020-09-02]
PubMed DOI Crossref
SAMHD1 phosphorylation and cytoplasmic relocalization after human cytomegalovirus infection limits its antiviral activity.
De Meo S, Dell'Oste V, Molfetta R, ..., Santoni A, Cerboni C
PLoS Pathog 16 (9) e1008855 [2020-09-00; online 2020-09-28]
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Rimeporide as a first- in-class NHE-1 inhibitor: Results of a phase Ib trial in young patients with Duchenne Muscular Dystrophy.
Previtali SC, Gidaro T, Díaz-Manera J, ..., Domingos J, Muntoni F
Pharmacol Res 159 (-) 104999 [2020-09-00; online 2020-06-12]
PubMed DOI Crossref
Promoter anchored interaction landscape of THP-1 macrophages captures early immune response processes.
Pradhananga S, Spalinskas R, Poujade FA, Eriksson P, Sahlén P
Cell Immunol 355 (-) 104148 [2020-09-00; online 2020-06-12]
PubMed DOI Crossref
PhenoChip: A single-cell phenomic platform for high-throughput photophysiological analyses of microalgae.
Behrendt L, Salek MM, Trampe EL, ..., Kühl M, Stocker R
Sci Adv 6 (36) eabb2754 [2020-09-00; online 2020-09-02]
Lars Behrendt SciLifeLab Fellow
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Perspectives from Ten Years of Protist Studies by High-Throughput Metabarcoding.
Santoferrara L, Burki F, Filker S, ..., Dunthorn M, McManus GB
J. Eukaryot. Microbiol. 67 (5) 612-622 [2020-09-00; online 2020-07-02]
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Linked-read sequencing enables haplotype-resolved resequencing at population scale.
Lutgen D, Ritter R, Olsen RA, ..., Suh A, Burri R
Mol Ecol Resour 20 (5) 1311-1322 [2020-09-00; online 2020-06-29]
PubMed DOI Crossref
Index hopping on the Illumina HiseqX platform and its consequences for ancient DNA studies.
van der Valk T, Vezzi F, Ormestad M, Dalén L, Guschanski K
Mol Ecol Resour 20 (5) 1171-1181 [2020-09-00; online 2019-05-05]
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Genetic association of gemcitabine/carboplatin-induced leukopenia and neutropenia in non-small cell lung cancer patients using whole-exome sequencing.
Svedberg A, Björn N, Sigurgeirsson B, ..., Lundeberg J, Gréen H
Lung Cancer 147 (-) 106-114 [2020-09-00; online 2020-07-12]
PubMed DOI Crossref
Extracellular vesicles in atrial fibrillation and stroke.
Thulin Å, Lindbäck J, Granger CB, ..., Lind L, Siegbahn A
Thromb. Res. 193 (-) 180-189 [2020-09-00; online 2020-07-15]
PubMed DOI Crossref
Ex vivo assessment of targeted therapies in a rare metastatic epithelial-myoepithelial carcinoma.
Mäkelä R, Arjonen A, Suryo Rahmanto A, ..., Kononen J, Rantala JK
Neoplasia 22 (9) 390-398 [2020-09-00; online 2020-07-06]
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Enzalutamide, an Androgen Receptor Antagonist, Enhances Myeloid Cell-Mediated Immune Suppression and Tumor Progression.
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Cancer Immunol Res 8 (9) 1215-1227 [2020-09-00; online 2020-07-13]
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Dembrower K, Wåhlin E, Liu Y, ..., Eklund M, Strand F
Lancet Digit Health 2 (9) e468-e474 [2020-09-00; online 2020-12-18]
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Comparative analysis of genome-wide DNA methylation in Neurospora.
Hosseini S, Meunier C, Nguyen D, Reimegård J, Johannesson H
Epigenetics 15 (9) 972-987 [2020-09-00; online 2020-03-31]
PubMed DOI Crossref
Cigarette smoking patterns preceding primary Sjögren's syndrome.
Mofors J, Björk A, Richardsdotter Andersson E, ..., Alfredsson L, Wahren-Herlenius M
RMD Open 6 (3) - [2020-09-00; online 2020-10-01]
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Bone morphogenetic protein receptors: Structure, function and targeting by selective small molecule kinase inhibitors.
Sanchez-Duffhues G, Williams E, Goumans MJ, Heldin CH, Ten Dijke P
Bone 138 (-) 115472 [2020-09-00; online 2020-06-06]
DOI Crossref
Basal Ganglia—A Motion Perspective
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Compr Physiol 10 (4) 1241-1275 [2020-09-00; online 2020-09-01]
PubMed DOI Crossref
Author Correction: Analysis of the Human Protein Atlas Image Classification competition.
Ouyang W, Winsnes CF, Hjelmare M, ..., Kappel C, Lundberg E
Nat. Methods 17 (9) 948 [2020-09-00; online 2020-08-08]
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Sci Adv 6 (38) - [2020-09-00; online 2020-09-16]
DOI Crossref
1135P Plasma proteomics in patients with metastatic cutaneous melanoma treated with targeted therapy
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Ann Oncol 31 (-) S760 [2020-09-00; online 2020-09-00]
PubMed DOI Crossref
Sex differences in oncogenic mutational processes.
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Nat Commun 11 (1) 4330 [2020-08-28; online 2020-08-28]
DOI Crossref
Lipoprotein particles interact with membranes and transfer their cargo without receptors
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- - (-) - [2020-08-28; online 2020-08-28]
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Comparison of serum exosome isolation methods on co-precipitated free microRNAs.
Cheng Y, Qu X, Dong Z, ..., Wang T, Xia W
PeerJ 8 (-) e9434 [2020-08-28; online 2020-08-28]
PubMed DOI Crossref
A potential for molecular simulation of compounds with linear moieties.
van der Spoel D, Henschel H, van Maaren PJ, Ghahremanpour MM, Costa LT
J Chem Phys 153 (8) 084503 [2020-08-28; online 2020-09-03]
PubMed DOI Crossref
Preoperative Fasting and General Anaesthesia Alter the Plasma Proteome.
Gyllensten U, Bosdotter Enroth S, Stålberg K, Sundfeldt K, Enroth S
Cancers (Basel) 12 (9) - [2020-08-27; online 2020-08-27]
PubMed DOI Crossref
High-Throughput Sequencing and Unsupervised Analysis of Formyltetrahydrofolate Synthetase (FTHFS) Gene Amplicons to Estimate Acetogenic Community Structure.
Singh A, Nylander JAA, Schnürer A, Bongcam-Rudloff E, Müller B
Front Microbiol 11 (-) 2066 [2020-08-27; online 2020-08-27]
PubMed DOI Crossref
µ Opioid Receptor Agonism for L-DOPA-Induced Dyskinesia in Parkinson's Disease.
Bezard E, Li Q, Hulme H, ..., Andren PE, Crossman AR
J. Neurosci. 40 (35) 6812-6819 [2020-08-26; online 2020-07-20]
DOI Crossref
Differences in structure and hibernation mechanism highlight diversification of the microsporidian ribosome
Ehrenbolger K, Jespersen N, Sharma H, ..., Vossbrinck CR, Barandun J
bioRxiv - (-) - [2020-08-26; online 2020-08-26]
Jonas Barandun SciLifeLab Fellow
PubMed DOI Crossref
Combined transcriptome and proteome profiling of the pancreatic β-cell response to palmitate unveils key pathways of β-cell lipotoxicity.
Lytrivi M, Ghaddar K, Lopes M, ..., Eizirik DL, Cnop M
BMC Genomics 21 (1) 590 [2020-08-26; online 2020-08-26]
PubMed DOI Crossref
Systems-Level Immunomonitoring from Acute to Recovery Phase of Severe COVID-19.
Rodriguez L, Pekkarinen PT, Lakshmikanth T, ..., Kekäläinen E, Brodin P
Cell Rep Med 1 (5) 100078 [2020-08-25; online 2020-08-05]
Camila Consiglio DDLS Fellow
PubMed DOI Crossref
Perturbation-based gene regulatory network inference to unravel oncogenic mechanisms.
Morgan D, Studham M, Tjärnberg A, ..., Nordling TEM, Sonnhammer ELL
Sci Rep 10 (1) 14149 [2020-08-25; online 2020-08-25]
PubMed DOI Crossref
Cereulide Synthetase Acquisition and Loss Events within the Evolutionary History of Group III Bacillus cereus Sensu Lato Facilitate the Transition between Emetic and Diarrheal Foodborne Pathogens.
Carroll LM, Wiedmann M
MBio 11 (4) - [2020-08-25; online 2020-08-25]
DDLS Fellow Laura Carroll
DOI Crossref
αKG inhibits Regulatory T cell differentiation by coupling lipidome remodelling to mitochondrial metabolism
Matias MI, Yong CS, Foroushani A, ..., Dardalhon V, Taylor N
- - (-) - [2020-08-24; online 2020-08-24]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Whole-genome sequencing and gene network modules predict gemcitabine/carboplatin-induced myelosuppression in non-small cell lung cancer patients.
Björn N, Badam TVS, Spalinskas R, ..., Gustafsson M, Gréen H
NPJ Syst Biol Appl 6 (1) 25 [2020-08-24; online 2020-08-24]
PubMed DOI Crossref
Toward a Computational Ecotoxicity Assay.
Kamerlin N, Delcey MG, Manzetti S, van der Spoel D
J Chem Inf Model 60 (8) 3792-3803 [2020-08-24; online 2020-07-21]
DOI Crossref
The spatial landscape of gene expression isoforms in tissue sections
Lebrigand K, Bergenstråhle J, Thrane K, ..., Waldmann R, Lundeberg J
bioRxiv - (-) - [2020-08-24; online 2020-08-24]
DOI Crossref
Small molecule inhibitor of OGG1 blocks oxidative DNA damage repair at telomeres and potentiates Methotrexate anticancer effects
Baquero JM, Benítez-Buelga C, Rajagopal V, ..., Benítez J, Osorio A
- - (-) - [2020-08-24; online 2020-08-24]
DOI Crossref
Dysregulation of macrophage PEPD in obesity determines adipose tissue fibro-inflammation and insulin resistance
Pellegrinelli V, Rodriguez-Cuenca S, Rouault C, ..., Clément K, Vidal-Puig A
- - (-) - [2020-08-24; online 2020-08-24]
DOI Crossref
Detection of SARS-CoV-2 using non-commercial RT-LAMP reagents and raw samples
Alekseenko A, Barrett D, Pareja-Sanchez Y, ..., Yin X, Pelechano V
- - (-) - [2020-08-24; online 2020-08-24]
SciLifeLab Fellow Simon Elsässer
DOI Crossref
5’XP sRNA-seq: Efficient Identification of Transcripts With and Without 5’ Phosphorylation Reveals Evolutionary Conserved Small RNA
Kugelberg U, Nätt D, Skog S, Kutter C, Öst A
- - (-) - [2020-08-23; online 2020-08-23]
Claudia Kutter SciLifeLab Fellow
DOI Crossref
Seroprevalence of Coronavirus Disease 2019 (COVID-19) Among Health Care Workers from Three Pandemic Hospitals of Turkey
Alkurt G, Murt A, Aydin Z, ..., Dinler Doganay G, Doganay L
medRxiv - (-) - [2020-08-22; online 2020-08-22]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Mapping DNA Methylation in Mammals: The State of the Art.
Lentini A, Nestor CE
Methods in molecular biology (Clifton, N.J.) 2198 (-) 37-50 [2020-08-22; online 2020-08-22]
Antonio Lentini DDLS Fellow
PubMed DOI Crossref
Analyzing DNA-Immunoprecipitation Sequencing Data.
Lentini A, Nestor CE
Methods in molecular biology (Clifton, N.J.) 2198 (-) 431-439 [2020-08-22; online 2020-08-22]
Antonio Lentini DDLS Fellow
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Natural killer cell immunotypes related to COVID-19 disease severity.
Maucourant C, Filipovic I, Ponzetta A, ..., Björkström NK, Karolinska COVID-19 Study Group
Sci Immunol 5 (50) - [2020-08-21; online 2020-08-23]
Antonio Lentini DDLS Fellow
PubMed DOI Crossref
High-Throughput Sequencing to Investigate Associations Between HLA Genes and Metamizole-Induced Agranulocytosis.
Cismaru AL, Grimm L, Rudin D, ..., Largiadèr CR, Amstutz U
Front Genet 11 (-) 951 [2020-08-21; online 2020-08-21]
DOI Crossref
A molecular timescale for the origin of red algal-derived plastids
Strassert JFH, Irisarri I, Williams TA, Burki F
- - (-) - [2020-08-21; online 2020-08-21]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Spatial Transcriptomics and In Situ Sequencing to Study Alzheimer's Disease.
Chen WT, Lu A, Craessaerts K, ..., Fiers M, De Strooper B
Cell 182 (4) 976-991.e19 [2020-08-20; online 2020-07-22]
PubMed DOI Crossref
Structural basis of mitochondrial translation.
Aibara S, Singh V, Modelska A, Amunts A
Elife 9 (-) - [2020-08-19; online 2020-08-19]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Small molecule inhibitor of OGG1 blocks oxidative DNA damage repair at telomeres and potentiates Methotrexate anticancer effects
Baquero JM, Benítez-Buelga C, Rajagopal V, ..., Benítez J, Osorio A
- - (-) - [2020-08-18; online 2020-08-18]
PubMed DOI Crossref
Modeling SHH-driven medulloblastoma with patient iPS cell-derived neural stem cells.
Susanto E, Marin Navarro A, Zhou L, ..., Falk A, Wilhelm M
Proc. Natl. Acad. Sci. U.S.A. 117 (33) 20127-20138 [2020-08-18; online 2020-08-03]
PubMed DOI Crossref
Key role of quinone in the mechanism of respiratory complex I.
Gutiérrez-Fernández J, Kaszuba K, Minhas GS, ..., Gallagher DT, Sazanov LA
Nat Commun 11 (1) 4135 [2020-08-18; online 2020-08-18]
PubMed DOI Crossref
High Cysteine Membrane Proteins (HCMPs) Are Up-Regulated During Giardia-Host Cell Interactions.
Peirasmaki D, Ma'ayeh SY, Xu F, ..., Liu J, Svärd SG
Front Genet 11 (-) 913 [2020-08-18; online 2020-08-18]
PubMed DOI Crossref
Direct label-free imaging of nanodomains in biomimetic and biological membranes by cryogenic electron microscopy.
Heberle FA, Doktorova M, Scott HL, ..., Waxham MN, Levental I
Proc. Natl. Acad. Sci. U.S.A. 117 (33) 19943-19952 [2020-08-18; online 2020-08-05]
DDLS Fellow Milka Doktorova
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Designing custom CRISPR libraries for hypothesis-driven drug target discovery.
Iyer VS, Jiang L, Shen Y, ..., Schmierer B, Wermeling F
Comput Struct Biotechnol J 18 (-) 2237-2246 [2020-08-18; online 2020-08-18]
DOI Crossref
Unexpected Acetylation of Endogenous Aliphatic Amines by Arylamine ‐Acetyltransferase NAT2
Conway LP, Rendo V, Correia MSP, ..., Sjöblom T, Globisch D
Angewandte Chemie 132 (34) 14448-14452 [2020-08-17; online 2020-07-08]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
Unexpected Acetylation of Endogenous Aliphatic Amines by Arylamine N-Acetyltransferase NAT2.
Conway LP, Rendo V, Correia MSP, ..., Sjöblom T, Globisch D
Angew. Chem. Int. Ed. Engl. 59 (34) 14342-14346 [2020-08-17; online 2020-07-08]
Daniel Globisch SciLifeLab Fellow
DOI Crossref
The limits of estimating COVID-19 intervention effects using Bayesian models
Bryant P, Elofsson A
- - (-) - [2020-08-16; online 2020-08-16]
DDLS Fellow Patrick Bryant
PubMed DOI Crossref
Platelet-Specific PDGFB Ablation Impairs Tumor Vessel Integrity and Promotes Metastasis.
Zhang Y, Cedervall J, Hamidi A, ..., Dimberg A, Olsson AK
Cancer Res. 80 (16) 3345-3358 [2020-08-15; online 2020-06-25]
DOI Crossref
Abstract 2371: FBXL12 modulates Fanconi anaemia-BRCA signaling under conditions of oncogene-induced replication stress
Brunner A, Johansson H, Kourtesakis A, ..., Lehtiö J, Sangfelt O
Cancer Res. 80 (16_Supplement) 2371-2371 [2020-08-15; online 2020-08-15]
DOI Crossref
Science meets politics A Dominant Character: The Radical Science and Restless Politics of J. B. S. Haldane Samanth Subramanian Norton, 2020. 400 pp.
Hughes PW
Science 369 (6505) 779-779 [2020-08-14; online 2020-08-14]
PubMed DOI Crossref
Crystal structures of human PAICS reveal substrate and product binding of an emerging cancer target.
Škerlová J, Unterlass J, Göttmann M, ..., Jemth AS, Stenmark P
J Biol Chem 295 (33) 11656-11668 [2020-08-14; online 2020-06-22]
DOI Crossref
Assembly and symmetry of the fungal E3BP-containing core of the Pyruvate Dehydrogenase Complex
Forsberg BO, Aibara S, Howard RJ, Mortezaei N, Lindahl E
- - (-) - [2020-08-14; online 2020-08-14]
Björn Forsberg DDLS Fellow
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Generation of ssDNA aptamers as diagnostic tool for Newcastle avian virus.
Marnissi B, Kamali-Moghaddam M, Ghram A, Hmila I
PLoS ONE 15 (8) e0237253 [2020-08-13; online 2020-08-13]
PubMed DOI Crossref
Drug Repositioning for P-Glycoprotein Mediated Co-Expression Networks in Colorectal Cancer.
Beklen H, Gulfidan G, Arga KY, Mardinoglu A, Turanli B
Front Oncol 10 (-) 1273 [2020-08-13; online 2020-08-13]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Pathway-specific model estimation for improved pathway annotation by network crosstalk.
Castresana-Aguirre M, Sonnhammer ELL
Sci Rep 10 (1) 13585 [2020-08-12; online 2020-08-12]
DOI Crossref
Genomically Complex Human Angiosarcoma and Canine Hemangiosarcoma Establish Convergent Angiogenic Transcriptional Programs Driven by Novel Gene Fusions
Kim JH, Megquier K, Thomas R, ..., Lindblad-Toh K, Modiano JF
- - (-) - [2020-08-12; online 2020-08-12]
PubMed DOI Crossref
Variations in Plasma Membrane Topography Can Explain Heterogenous Diffusion Coefficients Obtained by Fluorescence Correlation Spectroscopy.
Gesper A, Wennmalm S, Hagemann P, ..., Happel P, Parmryd I
Front Cell Dev Biol 8 (-) 767 [2020-08-11; online 2020-08-11]
PubMed DOI Crossref
Transcriptional mutagenesis dramatically alters genome-wide p53 transactivation landscape.
Liang S, Ezerskyte M, Wang J, Pelechano V, Dreij K
Sci Rep 10 (1) 13513 [2020-08-11; online 2020-08-11]
SciLifeLab Fellow
DOI Crossref
Genetic-substructure and complex demographic history of South African Bantu speakers
Sengupta D, Choudhury A, Fortes-Lima C, ..., Schlebusch CM, Ramsay M
- - (-) - [2020-08-11; online 2020-08-11]
PubMed DOI Crossref
Using Micro- and Macro-Level Network Metrics Unveils Top Communicative Gene Modules in Psoriasis.
Naderi R, Saadati Mollaei H, Elofsson A, Hosseini Ashtiani S
Genes (Basel) 11 (8) - [2020-08-10; online 2020-08-10]
PubMed DOI Crossref
Super-resolution RESOLFT microscopy of lipid bilayers using a fluorophore-switch dyad.
Frawley AT, Wycisk V, Xiong Y, ..., Eggeling C, Anderson HL
Chem Sci 11 (33) 8955-8960 [2020-08-10; online 2020-08-10]
Erdinc Sezgin SciLifeLab Fellow
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Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.
Dombrowski N, Williams TA, Sun J, ..., Rinke C, Spang A
Nat Commun 11 (1) 3939 [2020-08-07; online 2020-08-07]
PubMed DOI Crossref
The Antibody Society's antibody validation webinar series.
Voskuil JLA, Bandrowski A, Begley CG, ..., Williams C, Goodman SL
MAbs 12 (1) 1794421 [2020-08-05; online 2020-08-05]
DOI Crossref
Phylogenomic Insights into the Origin of Primary Plastids
Irisarri I, Strassert JFH, Burki F
bioRxiv - (-) - [2020-08-04; online 2020-08-04]
Fabien Burki SciLifeLab Fellow
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Fusion transcript detection using spatial transcriptomics.
Friedrich S, Sonnhammer ELL
BMC Med Genomics 13 (1) 110 [2020-08-04; online 2020-08-04]
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zOPT: an open source optical projection tomography system and methods for rapid 3D zebrafish imaging.
Zhang H, Waldmann L, Manuel R, ..., Haitina T, Allalou A
Biomed Opt Express 11 (8) 4290-4305 [2020-08-01; online 2020-07-15]
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Valganciclovir as Add-on to Standard Therapy in Glioblastoma Patients.
Stragliotto G, Pantalone MR, Rahbar A, Bartek J, Söderberg-Naucler C
Clin. Cancer Res. 26 (15) 4031-4039 [2020-08-01; online 2020-05-18]
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TissUUmaps: interactive visualization of large-scale spatial gene expression and tissue morphology data.
Solorzano L, Partel G, Wählby C
Bioinformatics 36 (15) 4363-4365 [2020-08-01; online 2020-05-26]
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Human RTEL1 associates with Poldip3 to facilitate responses to replication stress and R-loop resolution.
Björkman A, Johansen SL, Lin L, ..., Bartek J, Schou KB
Genes Dev. 34 (15-16) 1065-1074 [2020-08-01; online 2020-06-19]
SciLifeLab Fellow Simon Elsässer
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The regulatory role of PGC1α-related coactivator in response to drug-induced liver injury.
Buler M, Naessens T, Mattsson J, ..., Scarpulla RC, Andersson U
FASEB Bioadv 2 (8) 453-463 [2020-08-00; online 2020-07-11]
DOI Crossref
The means of reproduction: Book Review of Fusco, G. and A.Minelli. 2019. The Biology of Reproduction. Cambridge University Press, Cambridge, UK. xviii + 472 pp. ISBN: 978‐1‐10‐8758970. $47 USD.
Hughes PW
Evolution 74 (8) 1886-1889 [2020-08-00; online 2020-07-19]
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The importance of the ZBED6-IGF2 axis for metabolic regulation in mouse myoblast cells.
Younis S, Naboulsi R, Wang X, ..., Welsh N, Andersson L
FASEB J. 34 (8) 10250-10266 [2020-08-00; online 2020-06-19]
PubMed DOI Crossref
The cyanobacterial neurotoxin β-N-methylamino-L-alanine (BMAA) targets the olfactory bulb region.
Pierozan P, Piras E, Brittebo E, Karlsson O
Arch. Toxicol. 94 (8) 2799-2808 [2020-08-00; online 2020-05-20]
Oskar Karlsson SciLifeLab Fellow
PubMed DOI Crossref
Technologies for assessing vaccine responses in the very young.
Brodin P
Curr Opin Immunol 65 (-) 28-31 [2020-08-00; online 2020-04-24]
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Super-sonic speed of DNA synthesis in medulloblastoma.
Maya-Mendoza A, Bartek J
Nat Cancer 1 (8) 758-760 [2020-08-00; online 2020-08-01]
PubMed DOI Crossref
SWEDEGENE-a Swedish nation-wide DNA sample collection for pharmacogenomic studies of serious adverse drug reactions.
Hallberg P, Yue QY, Eliasson E, ..., Ås J, Wadelius M
Pharmacogenomics J. 20 (4) 579-585 [2020-08-00; online 2020-01-17]
PubMed DOI Crossref
SLC12A2 mutations cause NKCC1 deficiency with encephalopathy and impaired secretory epithelia.
Stödberg T, Magnusson M, Lesko N, ..., Stranneheim H, Wedell A
Neurol Genet 6 (4) e478 [2020-08-00; online 2020-07-02]
DOI Crossref
Real‐time analysis of switchable nanocomposites of magnesium pyrophosphates and rolling circle amplification products
Minero GAS, Fock J, Tian B, ..., Nilsson M, Fougt Hansen M
ChemNanoMat 6 (8) 1276-1282 [2020-08-00; online 2020-04-21]
PubMed DOI Crossref
Publisher Correction: GPCRmd uncovers the dynamics of the 3D-GPCRome.
Rodríguez-Espigares I, Torrens-Fontanals M, Tiemann JKS, ..., Guixà-González R, Selent J
Nat. Methods 17 (8) 861-862 [2020-08-00; online 2020-07-25]
Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Publisher Correction: Building an international consortium for tracking coronavirus health status.
Segal E, Zhang F, Lin X, ..., Vilo J, Wilmes P
Nat. Med. 26 (8) 1309 [2020-08-00; online 2020-06-28]
PubMed DOI Crossref
Predatory colponemids are the sister group to all other alveolates.
Tikhonenkov DV, Strassert JFH, Janouškovec J, ..., Burki F, Keeling PJ
Mol. Phylogenet. Evol. 149 (-) 106839 [2020-08-00; online 2020-04-21]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Oxygen sensing; a stunningly elegant molecular machinery highjacked in cancer.
Claesson-Welsh L
Ups. J. Med. Sci. 125 (3) 205-210 [2020-08-00; online 2020-06-24]
PubMed DOI Crossref
Neuroprotective effects of boron nitride nanoparticles in the experimental Parkinson's disease model against MPP+ induced apoptosis.
Küçükdoğru R, Türkez H, Arslan ME, ..., Cacciatore I, Di Stefano A
Metab Brain Dis 35 (6) 947-957 [2020-08-00; online 2020-03-25]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Nagashima-type palmoplantar keratosis in Finland caused by a SERPINB7 founder mutation.
Hannula-Jouppi K, Harjama L, Einarsdottir E, ..., Kere J, Ranki A
J Am Acad Dermatol 83 (2) 643-645 [2020-08-00; online 2019-11-07]
PubMed DOI Crossref
Molecular basis of mood and cognitive adverse events elucidated via a combination of pharmacovigilance data mining and functional enrichment analysis.
Andronis C, Silva JP, Lekka E, ..., Carvalho F, Savić MM
Arch. Toxicol. 94 (8) 2829-2845 [2020-08-00; online 2020-06-05]
PubMed DOI Crossref
Mapping the nucleolar proteome reveals a spatiotemporal organization related to intrinsic protein disorder.
Stenström L, Mahdessian D, Gnann C, ..., Thul PJ, Lundberg E
Mol Syst Biol 16 (8) e9469 [2020-08-00; online 2020-08-04]
DDLS Fellow Wei Ouyang
PubMed DOI Crossref
Long non-coding RNAs and TGF-β signaling in cancer.
Papoutsoglou P, Moustakas A
Cancer Sci. 111 (8) 2672-2681 [2020-08-00; online 2020-06-17]
PubMed DOI Crossref
Letter: safety of proton pump inhibitors during pregnancy-authors' reply.
Mei Li C, Brusselaers N
Aliment. Pharmacol. Ther. 52 (4) 740-741 [2020-08-00; online 2020-09-05]
PubMed DOI Crossref
Interference with pancreatic sympathetic signaling halts the onset of diabetes in mice.
Christoffersson G, Ratliff SS, von Herrath MG
Sci Adv 6 (35) eabb2878 [2020-08-00; online 2020-08-26]
Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
Integrating spatial gene expression and breast tumour morphology via deep learning.
He B, Bergenstråhle L, Stenbeck L, ..., Lundeberg J, Zou J
Nat Biomed Eng 4 (8) 827-834 [2020-08-00; online 2020-06-22]
PubMed DOI Crossref
Human ovarian cancer intrinsic mechanisms regulate lymphocyte activation in response to immune checkpoint blockade.
Natoli M, Bonito N, Robinson JD, Ghaem-Maghami S, Mao Y
Cancer Immunol. Immunother. 69 (8) 1391-1401 [2020-08-00; online 2020-03-21]
SciLifeLab Fellow Yumeng Mao
PubMed DOI Crossref
Genomic epidemiology of Campylobacter jejuni associated with asymptomatic pediatric infection in the Peruvian Amazon.
Pascoe B, Schiaffino F, Murray S, ..., Kosek MN, Sheppard SK
PLoS Negl Trop Dis 14 (8) e0008533 [2020-08-00; online 2020-08-10]
PubMed DOI Crossref
GPCRmd uncovers the dynamics of the 3D-GPCRome.
Rodríguez-Espigares I, Torrens-Fontanals M, Tiemann JKS, ..., Guixà-González R, Selent J
Nat. Methods 17 (8) 777-787 [2020-08-00; online 2020-07-13]
Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
Fibrin fragment E potentiates TGF-β-induced myofibroblast activation and recruitment.
Fuchs PÖ, Calitz C, Pavlović N, ..., Heindryckx F, Gerwins P
Cell. Signal. 72 (-) 109661 [2020-08-00; online 2020-04-22]
PubMed DOI Crossref
Editorial overview: Evolutionary and systems immunology - methods to understand human immune system variation.
Brodin P, Quintana-Murci L
Curr Opin Immunol 65 (-) iv [2020-08-00; online 2020-12-08]
PubMed DOI Crossref
Dietary metabolite profiling brings new insight into the relationship between nutrition and metabolic risk: An IMI DIRECT study.
Eriksen R, Perez IG, Posma JM, ..., Holmes E, Frost G
EBioMedicine 58 (-) 102932 [2020-08-00; online 2020-08-04]
PubMed DOI Crossref
Determinants of genetic variation across eco-evolutionary scales in pinnipeds.
Peart CR, Tusso S, Pophaly SD, ..., Shafer ABA, Wolf JBW
Nat Ecol Evol 4 (8) 1095-1104 [2020-08-00; online 2020-06-08]
PubMed DOI Crossref
Correction to: Human ovarian cancer intrinsic mechanisms regulate lymphocyte activation in response to immune checkpoint blockade.
Natoli M, Bonito N, Robinson JD, Ghaem-Maghami S, Mao Y
Cancer Immunol. Immunother. 69 (8) 1403-1408 [2020-08-00; online 2020-06-20]
SciLifeLab Fellow Yumeng Mao
PubMed DOI Crossref
Comprehensive analysis of RNA binding motif protein 3 (RBM3) in non-small cell lung cancer.
Salomonsson A, Micke P, Mattsson JSM, ..., Planck M, Brunnström H
Cancer Med 9 (15) 5609-5619 [2020-08-00; online 2020-06-03]
PubMed DOI Crossref
Chlamydial contribution to anaerobic metabolism during eukaryotic evolution.
Stairs CW, Dharamshi JE, Tamarit D, ..., Spang A, Ettema TJG
Sci Adv 6 (35) eabb7258 [2020-08-00; online 2020-08-26]
PubMed DOI Crossref
Building an international consortium for tracking coronavirus health status.
Segal E, Zhang F, Lin X, ..., Vilo J, Wilmes P
Nat. Med. 26 (8) 1161-1165 [2020-08-00; online 2020-06-04]
PubMed DOI Crossref
Birth size and cancer prognosis: a systematic review and meta-analysis.
Sharma S, Kohli C, Johnson L, ..., Brusselaers N, Nilsson PM
J Dev Orig Health Dis 11 (4) 309-316 [2020-08-00; online 2019-10-24]
PubMed DOI Crossref
Author Correction: Higher-order epistasis shapes the fitness landscape of a xenobiotic-degrading enzyme.
Yang G, Anderson DW, Baier F, ..., Bornberg-Bauer E, Tokuriki N
Nat. Chem. Biol. 16 (8) 930 [2020-08-00; online 2020-06-14]
PubMed DOI Crossref
Association between proteomics and obstructive sleep apnea phenotypes in a community-based cohort of women.
Ljunggren M, Theorell-Haglöw J, Freyhult E, ..., Janson C, Lindberg E
J Sleep Res 29 (4) e13041 [2020-08-00; online 2020-04-08]
PubMed DOI Crossref
Archaea in boreal Swedish lakes are diverse, dominated by Woesearchaeota and follow deterministic community assembly.
Juottonen H, Fontaine L, Wurzbacher C, ..., Peura S, Eiler A
Environ. Microbiol. 22 (8) 3158-3171 [2020-08-00; online 2020-06-03]
Sari Peura SciLifeLab Fellow
PubMed DOI Crossref
Apparent stiffness of vimentin intermediate filaments in living cells and its relation with other cytoskeletal polymers.
Smoler M, Coceano G, Testa I, Bruno L, Levi V
Biochim Biophys Acta Mol Cell Res 1867 (8) 118726 [2020-08-00; online 2020-04-19]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Amorphous nanosilica induced toxicity, inflammation and innate immune responses: A critical review.
Sharma N, Jha S
Toxicology 441 (-) 152519 [2020-08-00; online 2020-06-07]
PubMed DOI Crossref
Activation of β1 integrins and caveolin-1 by TF/FVIIa promotes IGF-1R signaling and cell survival.
Åberg M, Edén D, Siegbahn A
Apoptosis 25 (7-8) 519-534 [2020-08-00; online 2020-05-28]
PubMed DOI Crossref
A pan-cancer analysis of the frequency of DNA alterations across cell cycle activity levels.
Lundberg A, Lindström LS, Parker JS, ..., Bergh J, Tobin NP
Oncogene 39 (32) 5430-5440 [2020-08-00; online 2020-06-24]
Arian Lundberg DDLS Fellow
PubMed DOI Crossref
A novel alphaproteobacterium with a small genome identified from the digestive gland of multiple species of abalone.
Huang Z, Petersen JM, Martijn J, Ettema TJG, Shao Z
Environ Microbiol Rep 12 (4) 387-395 [2020-08-00; online 2020-04-30]
PubMed DOI Crossref
Visualizing drug binding interactions using microcrystal electron diffraction.
Clabbers MTB, Fisher SZ, Coinçon M, Zou X, Xu H
Commun Biol 3 (1) 417 [2020-07-31; online 2020-07-31]
DOI Crossref
The avian W chromosome is a refugium for endogenous retroviruses with likely effects on female-biased mutational load and genetic incompatibilities
Peona V, Palacios-Gimenez OM, Blommaert J, ..., Jern P, Suh A
- - (-) - [2020-07-31; online 2020-07-31]
PubMed DOI Crossref
Evaluating Thymic Function After Human Hematopoietic Stem Cell Transplantation in the Personalized Medicine Era.
Gaballa A, Clave E, Uhlin M, Toubert A, Arruda LCM
Front Immunol 11 (-) 1341 [2020-07-31; online 2020-07-31]
PubMed DOI Crossref
Automated GMP-Compliant Production of [68Ga]Ga-DO3A-Tuna-2 for PET Microdosing Studies of the Glucagon Receptor in Humans.
Wagner M, Doverfjord JG, Tillner J, ..., Eriksson O, Velikyan I
Pharmaceuticals (Basel, Switzerland) 13 (8) 176 [2020-07-31; online 2020-07-31]
Olof Eriksson SciLifeLab Fellow
DOI Crossref
NK cells integrate signals over large areas when building immune synapses but require local stimuli for degranulation
Verron Q, Forslund E, Brandt L, ..., Olofsson PE, Önfelt B
- - (-) - [2020-07-30; online 2020-07-30]
PubMed DOI Crossref
Corticotropin-Releasing Hormone (CRH) Gene Family Duplications in Lampreys Correlate With Two Early Vertebrate Genome Doublings.
Cardoso JCR, Bergqvist CA, Larhammar D
Front Neurosci 14 (-) 672 [2020-07-30; online 2020-07-30]
DOI Crossref
SAMHD1 promotes oncogene-induced replication stress
Zhang SM, Calderón-Montaño JM, Rudd SG
- - (-) - [2020-07-29; online 2020-07-29]
PubMed DOI Crossref
Prototypical pacemaker neurons interact with the resident microbiota.
Klimovich A, Giacomello S, Björklund Å, ..., Adameyko I, Bosch TCG
Proc. Natl. Acad. Sci. U.S.A. 117 (30) 17854-17863 [2020-07-28; online 2020-07-09]
PubMed DOI Crossref
Computational Studies of SARS-CoV-2 3CLpro: Insights from MD Simulations.
Grottesi A, Bešker N, Emerson A, ..., Cerchia C, Talarico C
Int J Mol Sci 21 (15) - [2020-07-28; online 2020-07-28]
PubMed DOI Crossref
A multiplex platform for digital measurement of circular DNA reaction products.
Björkesten J, Patil S, Fredolini C, Lönn P, Landegren U
Nucleic Acids Res. 48 (13) e73 [2020-07-27; online 2020-05-30]
DOI Crossref
Distinct microbial communities along the chronic oil pollution continuum of the Persian Gulf converge with oil spill accidents
Somee MR, Dastgheib SMM, Shavandi M, ..., Amoozegar MA, Mehrshad M
- - (-) - [2020-07-26; online 2020-07-26]
DOI Crossref
The Trans-Ancestral Genomic Architecture of Glycaemic Traits
Chen J, Spracklen CN, Marenne G, ..., Morris AP, Barroso I
- - (-) - [2020-07-25; online 2020-07-25]
DOI Crossref
Rpb4 and Puf3 imprint and post-transcriptionally control the stability of a common set of mRNAs in yeast
Garrido-Godino AI, Gupta I, Gutiérrez-Santiago F, ..., Pelechano V, Navarro F
- - (-) - [2020-07-25; online 2020-07-25]
SciLifeLab Fellow
DOI Crossref
Genome-wide Spatial Expression Profiling in FFPE Tissues
Villacampa EG, Larsson L, Kvastad L, ..., Carlson J, Lundeberg J
- - (-) - [2020-07-25; online 2020-07-25]
DOI Crossref
Single-cell classification using learned cell phenotypes
Chen Y, Lakshmikanth T, Mikes J, Brodin P
- - (-) - [2020-07-24; online 2020-07-24]
PubMed DOI Crossref
Decomposing Structural Response Due to Sequence Changes in Protein Domains with Machine Learning.
Bryant P, Elofsson A
J. Mol. Biol. 432 (16) 4435-4446 [2020-07-24; online 2020-05-30]
DDLS Fellow Patrick Bryant
PubMed DOI Crossref
Current Status of COVID-19 Therapies and Drug Repositioning Applications.
Altay O, Mohammadi E, Lam S, ..., Uhlen M, Mardinoglu A
iScience 23 (7) 101303 [2020-07-24; online 2020-06-20]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Author response: Structural basis of mitochondrial translation
Aibara S, Singh V, Modelska A, Amunts A
- - (-) - [2020-07-24; online 2020-07-24]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Multimodal Analysis of Composition and Spatial Architecture in Human Squamous Cell Carcinoma.
Ji AL, Rubin AJ, Thrane K, ..., Lundeberg J, Khavari PA
Cell 182 (2) 497-514.e22 [2020-07-23; online 2020-06-23]
DOI Crossref
Ancient DNA of Rickettsia felis and Toxoplasma gondii implicated in the death of a hunter-gatherer boy from South Africa, 2,000 years ago
Rifkin RF, Vikram S, Ramond JBJ, ..., Schlebusch CM, Lombard M
- - (-) - [2020-07-23; online 2020-07-23]
PubMed DOI Crossref
Extended-Spectrum-β-Lactamase- and Plasmid AmpC-Producing Escherichia coli Causing Community-Onset Bloodstream Infection: Association of Bacterial Clones and Virulence Genes with Septic Shock, Source of Infection, and Recurrence.
Fröding I, Hasan B, Sylvin I, ..., Nauclér P, Giske CG
Antimicrob. Agents Chemother. 64 (8) - [2020-07-22; online 2020-07-22]
PubMed DOI Crossref
Human Immune System Variation during 1 Year.
Lakshmikanth T, Muhammad SA, Olin A, ..., Uhlen M, Brodin P
Cell Reports 32 (3) 107923 [2020-07-21; online 2020-07-23]
PubMed DOI Crossref
Functionally distinct Purkinje cell types show temporal precision in encoding locomotion.
Chang W, Pedroni A, Hohendorf V, ..., Köster RW, Ampatzis K
Proc. Natl. Acad. Sci. U.S.A. 117 (29) 17330-17337 [2020-07-21; online 2020-07-06]
PubMed DOI Crossref
Population Genomics: How Do Cape Honey Bees Do Without Sex?
Webster MT
Curr. Biol. 30 (14) R820-R821 [2020-07-20; online 2020-07-22]
DOI Crossref
Infectious Disease Research in the Era of Big Data
Kasson PM
Annu Rev Biomed Data Sci 3 (1) 43-59 [2020-07-20; online 2020-07-20]
PubMed DOI Crossref
Validating Signal Transducer and Activator of Transcription (STAT) Protein-Inhibitor Interactions Using Biochemical and Cellular Thermal Shift Assays.
Attarha S, Reithmeier A, Busker S, Desroses M, Page BDG
ACS chemical biology 15 (7) 1842-1851 [2020-07-17; online 2020-07-02]
PubMed DOI Crossref
A brainwide atlas of synapses across the mouse life span.
Cizeron M, Qiu Z, Koniaris B, ..., Fransén E, Grant SGN
Science (New York, N.Y.) 369 (6501) 270-275 [2020-07-17; online 2020-06-11]
PubMed DOI Crossref
Translating GWAS-identified loci for cardiac rhythm and rate using an in vivo image- and CRISPR/Cas9-based approach.
von der Heyde B, Emmanouilidou A, Mazzaferro E, ..., Brooke HL, den Hoed M
Sci Rep 10 (1) 11831 [2020-07-16; online 2020-07-16]
DOI Crossref
Gene regulation of the avian malaria parasite Plasmodium relictum , during the different stages within the mosquito vector
Sekar V, Rivero A, Pigeault R, ..., Ahren D, Hellgren O
- - (-) - [2020-07-16; online 2020-07-16]
PubMed DOI Crossref
An Intuitively Understandable Quality Measure for Theoretical Vibrational Spectra.
Henschel H, van der Spoel D
J Phys Chem Lett 11 (14) 5471-5475 [2020-07-16; online 2020-06-25]
PubMed DOI Crossref
Genome-wide functional association networks: background, data & state-of-the-art resources.
Guala D, Ogris C, Müller N, Sonnhammer ELL
Brief. Bioinformatics 21 (4) 1224-1237 [2020-07-15; online 2019-07-10]
PubMed DOI Crossref
Development and characterisation of bilayered periosteum-inspired composite membranes based on sodium alginate-hydroxyapatite nanoparticles.
D'Elía NL, Rial Silva R, Sartuqui J, ..., Messina P, Mestres G
J Colloid Interface Sci 572 (-) 408-420 [2020-07-15; online 2020-03-25]
PubMed DOI Crossref
DC-SCRIPT affects mammary organoids branching morphogenesis by modulating the FGFR1-pERK signaling axis.
Tang C, van den Bijgaart RJE, Looman MWG, ..., Ansems M, Adema GJ
Dev. Biol. 463 (2) 101-109 [2020-07-15; online 2020-05-15]
PubMed DOI Crossref
Author Correction: Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson's disease.
Tiklová K, Nolbrant S, Fiorenzano A, ..., Perlmann T, Parmar M
Nat Commun 11 (1) 3630 [2020-07-15; online 2020-07-15]
DOI Crossref
A rooted phylogeny resolves early bacterial evolution
Coleman GA, Davín AA, Mahendrarajah T, ..., Szöllősi GJ, Williams TA
- - (-) - [2020-07-15; online 2020-07-15]
DOI Crossref
Spatial Deconvolution of HER2-positive Breast Tumors Reveals Novel Intercellular Relationships
Andersson A, Larsson L, Stenbeck L, ..., Engblom C, Lundeberg J
- - (-) - [2020-07-14; online 2020-07-14]
Camilla Engblom SciLifeLab Fellow
PubMed DOI Crossref
Seamless integration of image and molecular analysis for spatial transcriptomics workflows.
Bergenstråhle J, Larsson L, Lundeberg J
BMC Genomics 21 (1) 482 [2020-07-14; online 2020-07-14]
DOI Crossref
Dental ontogeny in the most primitive bony fish Lophosteus reveals the developmental relationship between teeth and dermal odontodes
Chen D, Blom H, Sanchez S, ..., Märss T, Ahlberg PE
- - (-) - [2020-07-14; online 2020-07-14]
PubMed DOI Crossref
Deep Proteomic Deconvolution of Interferons and HBV Transfection Effects on a Hepatoblastoma Cell Line.
Hodge K, Makjaroen J, Robinson J, Khoomrung S, Pisitkun T
ACS Omega 5 (27) 16796-16810 [2020-07-14; online 2020-06-26]
PubMed DOI Crossref
A Patient-Derived Cell Atlas Informs Precision Targeting of Glioblastoma.
Johansson P, Krona C, Kundu S, ..., Marino S, Nelander S
Cell Reports 32 (2) 107897 [2020-07-14; online 2020-07-16]
PubMed DOI Crossref
Cost-effectiveness analysis of repeated self-sampling for HPV testing in primary cervical screening: a randomized study.
Aarnio R, Östensson E, Olovsson M, Gustavsson I, Gyllensten U
BMC Cancer 20 (1) 645 [2020-07-13; online 2020-07-13]
DOI Crossref
Imaging Renal Ultrastructure using a Fast and Simple Optical Clearing and Swelling Protocol
Unnersjö-Jess D, Butt L, Höhne M, ..., Brismar H, Blom H
- - (-) - [2020-07-12; online 2020-07-12]
DOI Crossref
A diffusion-like process enables expansion of advantaged gene mutations in human colonic epithelium
Olpe C, Khamis D, Chukanova M, ..., Winton D, Morrissey E
- - (-) - [2020-07-12; online 2020-07-12]
DOI Crossref
Single-cell analysis of mosquito hemocytes identifies signatures of immune cell subtypes and cell differentiation
Kwon H, Mohammed M, Franzén O, Ankarklev J, Smith RC
- - (-) - [2020-07-11; online 2020-07-11]
DOI Crossref
The Immunology of Multisystem Inflammatory Syndrome in Children with COVID-19
Consiglio CR, Cotugno N, Sardh F, ..., Palma P, Brodin P
medRxiv - (-) - [2020-07-10; online 2020-07-10]
Camila Consiglio DDLS Fellow
DOI Crossref
Natural killer cell activation related to clinical outcome of COVID-19
Maucourant C, Filipovic I, Ponzetta A, ..., Strålin K, Björkström NK
- - (-) - [2020-07-10; online 2020-07-10]
Antonio Lentini DDLS Fellow
PubMed DOI Crossref
Suppressed Vascular Leakage and Myocardial Edema Improve Outcome From Myocardial Infarction.
Li X, Redfors B, Sáinz-Jaspeado M, ..., Levin M, Claesson-Welsh L
Front. Physiol. 11 (-) 763 [2020-07-09; online 2020-07-09]
PubMed DOI Crossref
Structural Basis of Inhibition of Insulin-Regulated Aminopeptidase by a Macrocyclic Peptidic Inhibitor.
Mpakali A, Saridakis E, Giastas P, ..., Hallberg M, Stratikos E
ACS Med. Chem. Lett. 11 (7) 1429-1434 [2020-07-09; online 2020-06-02]
PubMed DOI Crossref
Systems Biology Approaches to Understand the Host-Microbiome Interactions in Neurodegenerative Diseases.
Rosario D, Boren J, Uhlen M, ..., Mardinoglu A, Shoaie S
Front Neurosci 14 (-) 716 [2020-07-08; online 2020-07-08]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
DOI Crossref
Activation of endogenous retroviruses during brain development causes neuroinflammation
Jönsson ME, Garza R, Sharma Y, ..., Jern P, Jakobsson J
- - (-) - [2020-07-08; online 2020-07-08]
DOI Crossref
Solid Phase Synthesis of Sulfonimidamide Pseudopeptides and Library Generation
Chinthakindi PK, Benediktsdottir A, Arvidsson PI, Chen Y, Sandström A
Eur. J. Org. Chem. 2020 (25) 3796-3807 [2020-07-07; online 2020-03-20]
PubMed DOI Crossref
Pulsed Electric Fields Can Create Pores in the Voltage Sensors of Voltage-Gated Ion Channels.
Rems L, Kasimova MA, Testa I, Delemotte L
Biophys. J. 119 (1) 190-205 [2020-07-07; online 2020-06-08]
Ilaria Testa Lucie Delemotte SciLifeLab Fellow
DOI Crossref
Front Cover: Solid Phase Synthesis of Sulfonimidamide Pseudopeptides and Library Generation (Eur. J. Org. Chem. 25/2020)
Chinthakindi PK, Benediktsdottir A, Arvidsson PI, Chen Y, Sandström A
Eur. J. Org. Chem. 2020 (25) 3734-3734 [2020-07-07; online 2020-06-29]
PubMed DOI Crossref
Discovery and population genomics of structural variation in a songbird genus.
Weissensteiner MH, Bunikis I, Catalán A, ..., Warmuth VM, Wolf JBW
Nat Commun 11 (1) 3403 [2020-07-07; online 2020-07-07]
PubMed DOI Crossref
PTEN and DNA-PK determine sensitivity and recovery in response to WEE1 inhibition in human breast cancer.
Brunner A, Suryo Rahmanto A, Johansson H, ..., Larsson LG, Sangfelt O
Elife 9 (-) - [2020-07-06; online 2020-07-06]
DOI Crossref
Network analysis reveals how lipids and other cofactors influence membrane protein allostery
Westerlund AM, Fleetwood O, Perez-Conesa S, Delemotte L
bioRxiv - (-) - [2020-07-06; online 2020-07-06]
Lucie Delemotte SciLifeLab Fellow
DOI Crossref
Identification of ligand-specific G-protein coupled receptor states and prediction of downstream efficacy via data-driven modeling
Fleetwood O, Carlsson J, Delemotte L
- - (-) - [2020-07-06; online 2020-07-06]
Jens Carlsson Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Genome-wide association analysis of canine T zone lymphoma identifies link to hypothyroidism and a shared association with mast-cell tumors.
Labadie JD, Elvers I, Feigelson HS, ..., Burnett R, Avery AC
BMC Genomics 21 (1) 464 [2020-07-06; online 2020-07-06]
DOI Crossref
Cotranslational folding of alkaline phosphatase in the periplasm of Escherichia coli
Elfageih R, Karyolaimos A, Kemp G, ..., von Heijne G, Kudva R
- - (-) - [2020-07-06; online 2020-07-06]
DOI Crossref
Addressing the pooled amplification paradox with unique molecular identifiers in single-cell RNA-seq
Gustafsson J, Robinson J, Nielsen J, Pachter L
- - (-) - [2020-07-06; online 2020-07-06]
DOI Crossref
The ER membrane chaperone Shr3 acts in a progressive manner to assist the folding of related plasma membrane transport proteins
Myronidi I, Ring A, Ljungdahl PO
- - (-) - [2020-07-05; online 2020-07-05]
DOI Crossref
The effect of opening up the US on COVID-19 spread
Bryant P, Elofsson A
- - (-) - [2020-07-04; online 2020-07-04]
DDLS Fellow Patrick Bryant
DOI Crossref
Calmodulin acts as a state-dependent switch to control a cardiac potassium channel opening
Kang PW, Westerlund AM, Shi J, ..., Delemotte L, Cui J
bioRxiv - (-) - [2020-07-04; online 2020-07-04]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
TOX is expressed by exhausted and polyfunctional human effector memory CD8+ T cells.
Sekine T, Perez-Potti A, Nguyen S, ..., Betts MR, Buggert M
Sci Immunol 5 (49) - [2020-07-03; online 2020-07-06]
PubMed DOI Crossref
Spatio-molecular domains identified in the mouse subthalamic nucleus and neighboring glutamatergic and GABAergic brain structures.
Wallén-Mackenzie Å, Dumas S, Papathanou M, ..., König N, Björklund ÅK
Commun Biol 3 (1) 338 [2020-07-03; online 2020-07-03]
DOI Crossref
Molecular architecture of the developing mouse brain
La Manno G, Siletti K, Furlan A, ..., Lönnerberg P, Linnarsson S
- - (-) - [2020-07-03; online 2020-07-03]
DOI Crossref
Image Analysis of Biological Data using CellProfiler
Klemm A
- - (-) - [2020-07-03; online 2020-07-03]
PubMed DOI Crossref
Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase.
Wilkes MC, Siva K, Chen J, ..., Flygare J, Sakamoto KM
Nat Commun 11 (1) 3344 [2020-07-03; online 2020-07-03]
DOI Crossref
Comparison of Otolith Microstructure of Herring Larvae and Sibling Adults Reared Under Identical Early Life Conditions
Tonheim S, Slotte A, Andersson L, Folkvord A, Berg F
Front. Mar. Sci. 7 (-) - [2020-07-03; online 2020-07-03]
PubMed DOI Crossref
The Quest for Orthologs benchmark service and consensus calls in 2020.
Altenhoff AM, Garrayo-Ventas J, Cosentino S, ..., Sonnhammer E, Dessimoz C
Nucleic Acids Res. 48 (W1) W538-W545 [2020-07-02; online 2020-05-07]
DOI Crossref
Recombination of repeat elements generates somatic complexity in human genomes
Pascarella G, Hashimoto K, Busch A, ..., Frith M, Carninci P
- - (-) - [2020-07-02; online 2020-07-02]
DOI Crossref
A translational multiplex serology approach to profile the prevalence of anti-SARS-CoV-2 antibodies in home-sampled blood
Roxhed N, Bendes A, Dale M, ..., Fredolini C, Schwenk JM
- - (-) - [2020-07-02; online 2020-07-02]
SciLifeLab Fellow Simon Elsässer
DOI Crossref
A new long-read dog assembly uncovers thousands of exons and functional elements missing in the previous reference
Wang C, Wallerman O, Arendt ML, ..., Meadows JRS, Lindblad-Toh K
- - (-) - [2020-07-02; online 2020-07-02]
PubMed DOI Crossref
Y-Chromosome Variation in Southern African Khoe-San Populations Based on Whole-Genome Sequences.
Naidoo T, Xu J, Vicente M, ..., Jakobsson M, Schlebusch CM
Genome Biol Evol 12 (7) 1031-1039 [2020-07-01; online 2020-07-23]
DOI Crossref
The ribosome modulates folding inside the ribosomal exit tunnel
Wruck F, Tian P, Kudva R, ..., Tans SJ, Katranidis A
- - (-) - [2020-07-01; online 2020-07-01]
PubMed DOI Crossref
The Binding of CD93 to Multimerin-2 Promotes Choroidal Neovascularization.
Tosi GM, Neri G, Barbera S, ..., Galvagni F, Orlandini M
Invest. Ophthalmol. Vis. Sci. 61 (8) 30 [2020-07-01; online 2020-07-23]
PubMed DOI Crossref
Rapid Detection of COVID-19 Coronavirus Using a Reverse Transcriptional Loop-Mediated Isothermal Amplification (RT-LAMP) Diagnostic Platform.
Yu L, Wu S, Hao X, ..., Chen WH, Yin X
Clin. Chem. 66 (7) 975-977 [2020-07-01; online 2020-04-22]
SciLifeLab Fellow
PubMed DOI Crossref
Menopausal hormone therapy treatment options and ovarian cancer risk: A Swedish prospective population-based matched-cohort study.
Simin J, Tamimi RM, Callens S, Engstrand L, Brusselaers N
Int. J. Cancer 147 (1) 33-44 [2020-07-01; online 2019-10-23]
DOI Crossref
Mechanism and effects of the skeletal muscle Nav1.4 inhibition by cannabidiol
Ghovanloo MR, Choudhury K, Bandaru TS, ..., Goodchild SJ, Ruben PC
- - (-) - [2020-07-01; online 2020-07-01]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Loqusdb: added value of an observations database of local genomic variation.
Magnusson M, Eisfeldt J, Nilsson D, ..., Wedell A, Stranneheim H
BMC Bioinformatics 21 (1) 273 [2020-07-01; online 2020-07-01]
PubMed DOI Crossref
Heterodimeric Radiotracer Targeting PSMA and GRPR for Imaging of Prostate Cancer-Optimization of the Affinity towards PSMA by Linker Modification in Murine Model.
Lundmark F, Abouzayed A, Mitran B, ..., Rosenström U, Orlova A
Pharmaceutics 12 (7) - [2020-07-01; online 2020-07-01]
DOI Crossref
EukProt: A database of genome-scale predicted proteins across the diversity of eukaryotes
Richter DJ, Berney C, Strassert JFH, ..., Burki F, de Vargas C
bioRxiv - (-) - [2020-07-01; online 2020-07-01]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Diazotroph Genomes and Their Seasonal Dynamics in a Stratified Humic Bog Lake.
Fernandez L, Peura S, Eiler A, ..., McMahon KD, Bertilsson S
Front Microbiol 11 (-) 1500 [2020-07-01; online 2020-07-01]
Sari Peura SciLifeLab Fellow
PubMed DOI Crossref
Transcriptomes from German shepherd dogs reveal differences in immune activity between atopic dermatitis affected and control skin.
Tengvall K, Bergvall K, Olsson M, ..., Lindblad-Toh K, Andersson G
Immunogenetics 72 (5) 315-323 [2020-07-00; online 2020-06-18]
PubMed DOI Crossref
The protein expression profile of ACE2 in human tissues.
Hikmet F, Méar L, Edvinsson Å, ..., Uhlén M, Lindskog C
Mol Syst Biol 16 (7) e9610 [2020-07-00; online 2020-07-28]
PubMed DOI Crossref
The N-terminal peptide generated after activation of prophenoloxidase affects crayfish hematopoiesis.
Sirikharin R, Söderhäll K, Söderhäll I
Dev. Comp. Immunol. 108 (-) 103687 [2020-07-00; online 2020-03-24]
PubMed DOI Crossref
Support systems to guide clinical decision-making in precision oncology: The Cancer Core Europe Molecular Tumor Board Portal.
Tamborero D, Dienstmann R, Rachid MH, ..., Rodon J, Lehtiö J
Nat. Med. 26 (7) 992-994 [2020-07-00; online 2020-07-08]
PubMed DOI Crossref
Quo vadis microRNAs?
Fromm B, Keller A, Yang X, ..., Peterson KJ, Griffiths-Jones S
Trends in Genetics 36 (7) 461-463 [2020-07-00; online 2020-04-16]
Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
Proximity Ligation Assay as a Tool for Antibody Validation in Human Tissues.
Lindskog C, Backman M, Zieba A, ..., Landegren U, Pontén F
J. Histochem. Cytochem. 68 (7) 515-529 [2020-07-00; online 2020-06-30]
PubMed DOI Crossref
Membrane integration and topology of RIFIN and STEVOR proteins of the Plasmodium falciparum parasite.
Andersson A, Kudva R, Magoulopoulou A, ..., Nilsson I, Tellgren-Roth Å
FEBS J. 287 (13) 2744-2762 [2020-07-00; online 2019-12-26]
PubMed DOI Crossref
Inhibition of the prostaglandin D2-GPR44/DP2 axis improves human islet survival and function.
Abadpour S, Tyrberg B, Schive SW, ..., Scholz H, Winzell MS
Diabetologia 63 (7) 1355-1367 [2020-07-00; online 2020-04-29]
PubMed DOI Crossref
Influenza A viruses use multivalent sialic acid clusters for cell binding and receptor activation.
Sieben C, Sezgin E, Eggeling C, Manley S
PLoS Pathog 16 (7) e1008656 [2020-07-00; online 2020-07-08]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Inflammatory markers in women with postpartum depressive symptoms.
Bränn E, Fransson E, White RA, ..., Sundström-Poromaa I, Skalkidou A
J Neurosci Res 98 (7) 1309-1321 [2020-07-00; online 2018-09-05]
PubMed DOI Crossref
Growth-Inhibitory Activity of Bone Morphogenetic Protein 4 in Human Glioblastoma Cell Lines Is Heterogeneous and Dependent on Reduced SOX2 Expression.
Dalmo E, Johansson P, Niklasson M, ..., Nelander S, Westermark B
Mol. Cancer Res. 18 (7) 981-991 [2020-07-00; online 2020-03-31]
PubMed DOI Crossref
Gastric Microbiota in a Low-Helicobacter pylori Prevalence General Population and Their Associations With Gastric Lesions.
Ndegwa N, Ploner A, Andersson AF, ..., Agreus L, Ye W
Clin Transl Gastroenterol 11 (7) e00191 [2020-07-00; online 2020-08-09]
PubMed DOI Crossref
GDF-15 is associated with sudden cardiac death due to incident myocardial infarction.
Andersson J, Fall T, Delicano R, Wennberg P, Jansson JH
Resuscitation 152 (-) 165-169 [2020-07-00; online 2020-05-21]
PubMed DOI Crossref
Female-biased gene flow between two species of Darwin's finches.
Lamichhaney S, Han F, Webster MT, ..., Grant PR, Andersson L
Nat Ecol Evol 4 (7) 979-986 [2020-07-00; online 2020-05-04]
PubMed DOI Crossref
Facets of individual-specific health signatures determined from longitudinal plasma proteome profiling.
Dodig-Crnković T, Hong MG, Thomas CE, ..., Uhlén M, Schwenk JM
EBioMedicine 57 (-) 102854 [2020-07-00; online 2020-07-03]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
DNA surface exploration and operator bypassing during target search.
Marklund E, van Oosten B, Mao G, ..., Elf J, Deindl S
Nature 583 (7818) 858-861 [2020-07-00; online 2020-06-24]
Daniel Globisch Emil Marklund SciLifeLab Fellow Sebastian Deindl
PubMed DOI Crossref
DNA demethylation regulates gene expression in IgE-activated mouse mast cells.
Paivandy A, Grujic M, Rafati N, Pejler G
Allergy 75 (7) 1776-1780 [2020-07-00; online 2020-02-12]
PubMed DOI Crossref
Comparative genomics reveals different population structures associated with host and geographic origin in antimicrobial-resistant Salmonella enterica.
Liao J, Orsi RH, Carroll LM, Wiedmann M
Environ. Microbiol. 22 (7) 2811-2828 [2020-07-00; online 2020-04-27]
DDLS Fellow Laura Carroll
PubMed DOI Crossref
Colibactin DNA-damage signature indicates mutational impact in colorectal cancer.
Dziubańska-Kusibab PJ, Berger H, Battistini F, ..., Aaltonen LA, Meyer TF
Nat. Med. 26 (7) 1063-1069 [2020-07-00; online 2020-06-01]
PubMed DOI Crossref
Characterization of More Selective Central Nervous System Nrf2-Activating Novel Vinyl Sulfoximine Compounds Compared to Dimethyl Fumarate.
Carlström KE, Chinthakindi PK, Espinosa B, ..., Piehl F, Johansson K
Neurotherapeutics 17 (3) 1142-1152 [2020-07-00; online 2020-05-13]
PubMed DOI Crossref
Cell-type-resolved proteomic analysis of the human liver.
Ölander M, Wiśniewski JR, Artursson P
Liver Int. 40 (7) 1770-1780 [2020-07-00; online 2020-04-12]
PubMed DOI Crossref
Base-pair conformational switch modulates miR-34a targeting of Sirt1 mRNA.
Baronti L, Guzzetti I, Ebrahimi P, ..., Chen AA, Petzold K
Nature 583 (7814) 139-144 [2020-07-00; online 2020-05-27]
PubMed DOI Crossref
AXL and CAV-1 play a role for MTH1 inhibitor TH1579 sensitivity in cutaneous malignant melanoma.
Das I, Gad H, Bräutigam L, ..., Egyházi Brage S, Warpman Berglund U
Cell Death Differ. 27 (7) 2081-2098 [2020-07-00; online 2020-01-09]
PubMed DOI Crossref
A systems biology approach for studying neurodegenerative diseases.
Lam S, Bayraktar A, Zhang C, ..., Uhlen M, Mardinoglu A
Drug Discov. Today 25 (7) 1146-1159 [2020-07-00; online 2020-05-19]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
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Gurwitz KT, Singh Gaur P, Bellis LJ, ..., Morgan SL, Rustici G
PLoS Comput Biol 16 (7) e1007976 [2020-07-00; online 2020-07-23]
PubMed DOI Crossref
A 2018-2019 patent review of metallo beta-lactamase inhibitors.
Reddy N, Shungube M, Arvidsson PI, ..., Govender T, Naicker T
Expert Opin Ther Pat 30 (7) 541-555 [2020-07-00; online 2020-05-20]
PubMed DOI Crossref
The evolution of the Puf superfamily of proteins across the tree of eukaryotes.
Najdrová V, Stairs CW, Vinopalová M, Voleman L, Doležal P
BMC Biol. 18 (1) 77 [2020-06-30; online 2020-06-30]
PubMed DOI Crossref
High content drug screening for Fanconi anemia therapeutics.
Montanuy H, Camps-Fajol C, Carreras-Puigvert J, ..., Minguillón J, Surrallés J
Orphanet J Rare Dis 15 (1) 170 [2020-06-30; online 2020-06-30]
PubMed DOI Crossref
Genome assembly of the basket willow, Salix viminalis, reveals earliest stages of sex chromosome expansion.
Almeida P, Proux-Wera E, Churcher A, ..., Berlin S, Mank JE
BMC Biol. 18 (1) 78 [2020-06-30; online 2020-06-30]
PubMed DOI Crossref
Proof-of-concept for CRISPR/Cas9 gene editing in human preadipocytes: Deletion of FKBP5 and PPARG and effects on adipocyte differentiation and metabolism.
Kamble PG, Hetty S, Vranic M, ..., Pereira MJ, Eriksson JW
Sci Rep 10 (1) 10565 [2020-06-29; online 2020-06-29]
DOI Crossref
Interconnected assembly factors regulate the biogenesis of mitoribosomal large subunit
Tobiasson V, Gahura O, Aibara S, ..., Zíková A, Amunts A
bioRxiv - (-) - [2020-06-29; online 2020-06-29]
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Electrowetting diminishes contact line friction in molecular wetting
Johansson P, Hess B
Phys. Rev. Fluids 5 (6) - [2020-06-29; online 2020-06-29]
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An efficient single-cell transcriptomics workflow for microbial eukaryotes benchmarked on Giardia intestinalis cells.
Onsbring H, Tice AK, Barton BT, Brown MW, Ettema TJG
BMC Genomics 21 (1) 448 [2020-06-29; online 2020-06-29]
PubMed DOI Crossref
Enhancing a de novo enzyme activity by computationally-focused ultra-low-throughput screening.
Risso VA, Romero-Rivera A, Gutierrez-Rus LI, ..., Sanchez-Ruiz JM, Kamerlin SCL
Chem Sci 11 (24) 6134-6148 [2020-06-28; online 2020-05-19]
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Whole genome sequencing of familial isolated oesophagus atresia uncover shared structural variants.
Klar J, Engstrand-Lilja H, Maqbool K, ..., Feuk L, Dahl N
BMC Med Genomics 13 (1) 85 [2020-06-26; online 2020-06-26]
PubMed DOI Crossref
Focus on the spectra that matter by clustering of quantification data in shotgun proteomics.
The M, Käll L
Nat Commun 11 (1) 3234 [2020-06-26; online 2020-06-26]
PubMed DOI Crossref
RNA-seq reveals altered gene expression levels in proximal tubular cell cultures compared to renal cortex but not during early glucotoxicity.
Nilsson LM, Castresana-Aguirre M, Scott L, Brismar H
Sci Rep 10 (1) 10390 [2020-06-25; online 2020-06-25]
PubMed DOI Crossref
Molecular Structure of Sphingomyelin in Fluid Phase Bilayers Determined by the Joint Analysis of Small-Angle Neutron and X-ray Scattering Data.
Doktorova M, Kučerka N, Kinnun JJ, ..., Katsaras J, Heberle FA
J Phys Chem B 124 (25) 5186-5200 [2020-06-25; online 2020-06-16]
DDLS Fellow Milka Doktorova
DOI Crossref
The overlap of genetic susceptibility to schizophrenia and cardiometabolic disease can be used to identify metabolically different groups of individuals
Strawbridge RJ, Johnston KJA, Bailey MES, ..., Ward J, Smith DJ
- - (-) - [2020-06-24; online 2020-06-24]
PubMed DOI Crossref
Whole-genome sequence association analysis of blood proteins in a longitudinal wellness cohort.
Zhong W, Gummesson A, Tebani A, ..., Fagerberg L, Uhlén M
Genome Med 12 (1) 53 [2020-06-23; online 2020-06-23]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
Transcriptional output, cell-type densities, and normalization in spatial transcriptomics.
Saiselet M, Rodrigues-Vitória J, Tourneur A, ..., Maenhaut C, Detours V
J Mol Cell Biol 12 (11) 906-908 [2020-06-23; online 2020-06-24]
PubMed DOI Crossref
Skeletal Muscle Transcriptomic Comparison between Long-Term Trained and Untrained Men and Women.
Chapman MA, Arif M, Emanuelsson EB, ..., Mardinoglu A, Sundberg CJ
Cell Reports 31 (12) 107808 [2020-06-23; online 2020-06-25]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Site-Specific Incorporation of Two ncAAs for Two-Color Bioorthogonal Labeling and Crosslinking of Proteins on Live Mammalian Cells.
Meineke B, Heimgärtner J, Eirich J, Landreh M, Elsässer SJ
Cell Reports 31 (12) 107811 [2020-06-23; online 2020-06-25]
SciLifeLab Fellow Simon Elsässer
DOI Crossref
SARS-CoV-2 exposure, symptoms and seroprevalence in health care workers
Rudberg AS, Havervall S, Månberg A, ..., Hober S, Thålin C
- - (-) - [2020-06-23; online 2020-06-23]
PubMed DOI Crossref
Imaging using radiolabelled targeted proteins: radioimmunodetection and beyond.
Garousi J, Orlova A, Frejd FY, Tolmachev V
EJNMMI Radiopharm Chem 5 (1) 16 [2020-06-23; online 2020-06-23]
DOI Crossref
High-throughput 5’P sequencing enables the study of degradation-associated ribosome stalls
Zhang Y, Pelechano V
bioRxiv - (-) - [2020-06-23; online 2020-06-23]
SciLifeLab Fellow
PubMed DOI Crossref
Cotranslational folding cooperativity of contiguous domains of α-spectrin.
Kemp G, Nilsson OB, Tian P, Best RB, von Heijne G
Proc. Natl. Acad. Sci. U.S.A. 117 (25) 14119-14126 [2020-06-23; online 2020-06-08]
PubMed DOI Crossref
Amyloid precursor protein-b facilitates cell adhesion during early development in zebrafish.
Banote RK, Chebli J, Şatır TM, ..., Abramsson A, Zetterberg H
Sci Rep 10 (1) 10127 [2020-06-23; online 2020-06-23]
PubMed DOI Crossref
Altered levels of CSF proteins in patients with FTD, presymptomatic mutation carriers and non-carriers.
Remnestål J, Öijerstedt L, Ullgren A, ..., Graff C, Nilsson P
Transl Neurodegener 9 (1) 27 [2020-06-23; online 2020-06-23]
PubMed DOI Crossref
Using Predicted Bioactivity Profiles to Improve Predictive Modeling.
Norinder U, Spjuth O, Svensson F
J Chem Inf Model 60 (6) 2830-2837 [2020-06-22; online 2020-05-15]
DOI Crossref
Mapping cell structure across scales by fusing protein images and interactions
Qin Y, Winsnes CF, Huttlin EL, ..., Lundberg E, Ideker T
- - (-) - [2020-06-22; online 2020-06-22]
DDLS Fellow Wei Ouyang
DOI Crossref
Author response: PTEN and DNA-PK determine sensitivity and recovery in response to WEE1 inhibition in human breast cancer
Brunner A, Suryo Rahmanto A, Johansson H, ..., Larsson LG, Sangfelt O
- - (-) - [2020-06-22; online 2020-06-22]
DOI Crossref
Engineered human mesenchymal stem cells as new vaccine platform for COVID-19
Liu J, Jiao H, Yin X
- - (-) - [2020-06-20; online 2020-06-20]
DOI Crossref
Characterization of the dynamic resting state of a pentameric ligand-gated ion channel by cryo-electron microscopy and simulations
Rovšnik U, Zhuang Y, Axelsson L, ..., Howard R, Lindahl E
- - (-) - [2020-06-20; online 2020-06-20]
Björn Forsberg DDLS Fellow
PubMed DOI Crossref
Successful delivery of large-size CRISPR/Cas9 vectors in hard-to-transfect human cells using small plasmids.
Søndergaard JN, Geng K, Sommerauer C, ..., Yin X, Kutter C
Commun Biol 3 (1) 319 [2020-06-19; online 2020-06-19]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Regio- and Stereoselective Synthesis of Allylic Spiroethers (Spirobenzofuranes) via an Intramolecular Mizoroki-Heck Reaction.
Adeyemi A, Odell LR, Larhed M
J. Org. Chem. 85 (12) 7648-7657 [2020-06-19; online 2020-06-01]
DOI Crossref
Inferring Tumor Progression in Large Datasets
Neyshabouri MM, Jun SH, Lagergren J
- - (-) - [2020-06-19; online 2020-06-19]
PubMed DOI Crossref
Adipose tissue morphology, imaging and metabolomics predicting cardiometabolic risk and family history of type 2 diabetes in non-obese men.
Rawshani A, Eliasson B, Rawshani A, ..., Rosengren A, Smith U
Sci Rep 10 (1) 9973 [2020-06-19; online 2020-06-19]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Harmonization of quality metrics and power calculation in multi-omic studies.
Tarazona S, Balzano-Nogueira L, Gómez-Cabrero D, ..., Westerhuis JA, Conesa A
Nat Commun 11 (1) 3092 [2020-06-18; online 2020-06-18]
PubMed DOI Crossref
Ciliate mitoribosome illuminates evolutionary steps of mitochondrial translation.
Tobiasson V, Amunts A
Elife 9 (-) e59264 [2020-06-18; online 2020-06-18]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Theoretical insights on helix repacking as the origin of P-glycoprotein promiscuity.
Bonito CA, Ferreira RJ, Ferreira MU, ..., Cordeiro MNDS, Dos Santos DJVA
Sci Rep 10 (1) 9823 [2020-06-17; online 2020-06-17]
PubMed DOI Crossref
High frequency of intermediary alleles in the HTT gene in Northern Sweden - The Swedish Huntingtin Alleles and Phenotype (SHAPE) study.
Sundblom J, Niemelä V, Ghazarian M, ..., Söderberg S, Stattin EL
Sci Rep 10 (1) 9853 [2020-06-17; online 2020-06-17]
PubMed DOI Crossref
Structural basis for allosteric transitions of a multidomain pentameric ligand-gated ion channel.
Hu H, Howard RJ, Bastolla U, Lindahl E, Delarue M
Proc. Natl. Acad. Sci. U.S.A. 117 (24) 13437-13446 [2020-06-16; online 2020-06-01]
DOI Crossref
Chanjo: Clincal grade sequence coverage analysis
Andeer R, Magnusson M, Wedell A, Stranneheim H
F1000Res 9 (-) 615 [2020-06-16; online 2020-06-16]
DOI Crossref
Point-of-Care Approaches for Meningitis Diagnosis in a Low-Resource Setting (Southwestern Uganda): Observational Cohort Study Protocol of the “PI-POC” Trial (Preprint)
Gaudenzi G, Kumbakumba E, Rasti R, ..., Mwanga-Amumpaire J, Alfvén T
- - (-) - [2020-06-15; online 2020-06-15]
PubMed DOI Crossref
Gefitinib and Afatinib Show Potential Efficacy for Fanconi Anemia-Related Head and Neck Cancer.
Montanuy H, Martínez-Barriocanal Á, Antonio Casado J, ..., Minguillón J, Surrallés J
Clin. Cancer Res. 26 (12) 3044-3057 [2020-06-15; online 2020-01-31]
PubMed DOI Crossref
Evaluating the Therapeutic Efficacy of Mono- and Bivalent Affibody-Based Fusion Proteins Targeting HER3 in a Pancreatic Cancer Xenograft Model.
Leitao CD, Rinne SS, Altai M, ..., Ståhl S, Orlova A
Pharmaceutics 12 (6) - [2020-06-13; online 2020-06-13]
DOI Crossref
Resin-acid derivatives bind to multiple sites on the voltage-sensor domain of the Saker channel
Silverå Ejneby M, Gromova A, Ottosson NE, ..., Elinder F, Delemotte L
- - (-) - [2020-06-12; online 2020-06-12]
Lucie Delemotte SciLifeLab Fellow
DOI Crossref
Peer Review Report For: A community proposal to integrate structural bioinformatics activities in ELIXIR (3D-Bioinfo Community) [version 1; peer review: 1 approved, 3 approved with reservations]
- - (-) - [2020-06-11; online 2020-06-11]
DOI Crossref
Influence of nanobody binding on fluorescence emission, mobility and organization of GFP-tagged proteins
Schneider F, Eggeling C, Sezgin E
- - (-) - [2020-06-11; online 2020-06-11]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Distinct pre-initiation steps in human mitochondrial translation.
Khawaja A, Itoh Y, Remes C, ..., Amunts A, Rorbach J
Nat Commun 11 (1) 2932 [2020-06-10; online 2020-06-10]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Bacterial protein domains with a novel Ig-like fold target human CEACAM receptors
van Sorge NM, Bonsor DA, Deng L, ..., Lindahl G, McCarthy AJ
- - (-) - [2020-06-10; online 2020-06-10]
PubMed DOI Crossref
Whole-genome sequencing of glioblastoma reveals enrichment of non-coding constraint mutations in known and novel genes.
Sakthikumar S, Roy A, Haseeb L, ..., Lindblad-Toh K, Forsberg-Nilsson K
Genome Biol. 21 (1) 127 [2020-06-09; online 2020-06-09]
DOI Crossref
Spritz: A Proteogenomic Database Engine
Cesnik AJ, Miller RM, Ibrahim K, ..., Frey BL, Smith LM
- - (-) - [2020-06-09; online 2020-06-09]
DOI Crossref
Chaining with Overlaps Revisited
Sahlin K, Mäkinen V
31st Annual Symposium on Combinatorial Pattern Matching (CPM 2020) 161 (-) 25:1--25:12 [2020-06-09; online 2020-06-09]
Kristoffer Sahlin SciLifeLab Fellow
DOI Crossref
Author response: Ciliate mitoribosome illuminates evolutionary steps of mitochondrial translation
Tobiasson V, Amunts A
- - (-) - [2020-06-08; online 2020-06-08]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Sensitive mass spectrometric analysis of carbonyl metabolites in human urine and fecal samples using chemoselective modification.
Lin W, Conway LP, Block A, ..., Löhr JM, Globisch D
Analyst 145 (11) 3822-3831 [2020-06-07; online 2020-05-12]
Daniel Globisch SciLifeLab Fellow
DOI Crossref
An In-Silico Analysis of Drugs Potentially Modulating the Cytokine Storm Triggered by SARS-CoV-2 Infection<strong> </strong>
Sanchez-Burgos L, Gómez-López G, Al-Shahrour F, Fernandez-Capetillo O
- - (-) - [2020-06-07; online 2020-06-07]
PubMed DOI Crossref
Nuclear Receptor Binding Protein 2 Is Downregulated in Medulloblastoma, and Reduces Tumor Cell Survival upon Overexpression.
Xiong A, Roy A, Spyrou A, ..., Swartling FJ, Forsberg-Nilsson K
Cancers (Basel) 12 (6) - [2020-06-06; online 2020-06-06]
PubMed DOI Crossref
The regulation and pharmacological modulation of immune complex induced type III IFN production by plasmacytoid dendritic cells.
Hjorton K, Hagberg N, Pucholt P, Eloranta ML, Rönnblom L
Arthritis Res Ther 22 (1) 130 [2020-06-05; online 2020-06-05]
DOI Crossref
Systems-level immunomonitoring from acute to recovery phase of severe COVID-19
Rodriguez L, Pekkarinen P, Lakshmikanth T, ..., Kekäläinen E, Brodin P
medRxiv - (-) - [2020-06-05; online 2020-06-05]
Camila Consiglio DDLS Fellow
DOI Crossref
Metabolic Atlas – a website for exploration and visualization of metabolic networks
Anton M, Cholley PE, Robinson JL, ..., Svensson LT, Nielsen J
- - (-) - [2020-06-05; online 2020-06-05]
DOI Crossref
High-fat diet impacts the colon and its transcriptome in a sex-dependent manner that is modifiable by estrogens
Hases L, Archer A, Indukuri R, ..., Korach-André M, Williams C
- - (-) - [2020-06-04; online 2020-06-04]
DOI Crossref
Evolutionarily related small viral fusogens hijack distinct but modular actin nucleation pathways to drive cell-cell fusion
Chan KMC, Arthur AL, Morstein J, ..., Drubin DG, Fletcher DA
- - (-) - [2020-06-04; online 2020-06-04]
PubMed DOI Crossref
Trial watch : the gut microbiota as a tool to boost the clinical efficacy of anticancer immunotherapy.
Daillère R, Derosa L, Bonvalet M, ..., Kroemer G, Zitvogel L
Oncoimmunology 9 (1) 1774298 [2020-06-03; online 2020-06-03]
DOI Crossref
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Babačić H, Lehtiö J, Pernemalm M
- - (-) - [2020-06-02; online 2020-06-02]
DOI Crossref
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Hanke L, Perez LV, Sheward DJ, ..., Murrell B, McInerney GM
- - (-) - [2020-06-02; online 2020-06-02]
DOI Crossref
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Høye E, Fromm B, Böttger PHM, ..., Hovig E, Flatmark K
- - (-) - [2020-06-02; online 2020-06-02]
DOI Crossref
SO042WHOLE GENOME SEQUENCING OF HUMAN KIDNEY PROGENITORS IDENTIFIES A MUTATION-PRONE CELL TYPE IN THE PROXIMAL TUBULE
Franco I, Helgadottir H, Moggio A, ..., Supek F, Eriksson M
Nephrol. Dial. Transplant. 35 (Supplement_3) - [2020-06-01; online 2020-06-06]
PubMed DOI Crossref
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Friedrich S, Barbulescu R, Helleday T, Sonnhammer ELL
BMC Med Genomics 13 (1) 76 [2020-06-01; online 2020-06-01]
PubMed DOI Crossref
Breeze: an integrated quality control and data analysis application for high-throughput drug screening.
Potdar S, Ianevski A, Mpindi JP, ..., Saarela J, Östling P
Bioinformatics 36 (11) 3602-3604 [2020-06-01; online 2020-03-03]
DOI Crossref
1270The epidemiological and phenotypic characteristics of SCD victims with ARVC in Sweden between 2000-2010: a Nationwide study
Kommata V, Delgado-Vega A, Wisten A, Hagstrom E, Stattin EL
Europace 22 (Supplement_1) - [2020-06-01; online 2020-06-18]
PubMed DOI Crossref
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Brodin P
Acta Paediatr 109 (6) 1082-1083 [2020-06-00; online 2020-04-15]
PubMed DOI Crossref
Translational profiling of macrophages infected with Leishmania donovani identifies mTOR- and eIF4A-sensitive immune-related transcripts.
Chaparro V, Leroux LP, Masvidal L, ..., Larsson O, Jaramillo M
PLoS Pathog 16 (6) e1008291 [2020-06-00; online 2020-06-01]
PubMed DOI Crossref
Size-Dependent Pulmonary Impact of Thin Graphene Oxide Sheets in Mice: Toward Safe-by-Design.
Rodrigues AF, Newman L, Jasim D, ..., Kostarelos K, Bussy C
Adv Sci (Weinh) 7 (12) 1903200 [2020-06-00; online 2020-05-07]
DOI Crossref
SAT0335 SERUM AND BALF-DERIVED ANTI-JO1 AUTOANTIBODIES EXHIBIT HIGH REACTIVITY TO DISTINCT HISRS DOMAINS AND ASSOCIATE WITH LUNG AND JOINT INVOLVEMENT IN PATIENTS WITH IIM/ASS
Notarnicola A, Preger C, Lundström S, ..., Lundberg IE, Cerqueira C
Ann Rheum Dis 79 (-) 1113-1114 [2020-06-00; online 2020-06-00]
DOI Crossref
SAT0288 CHARACTERIZATION OF ANTI-AMINOACYL TRNA SYNTHETASE AUTOANTIBODIES IN PATIENTS WITH IDIOPATHIC INFLAMMATORY MYOPATHIES
Preger C, Notarnicola A, Hellström C, ..., Gräslund S, Jakobsson PJ
Ann Rheum Dis 79 (-) 1088-1089 [2020-06-00; online 2020-06-00]
PubMed DOI Crossref
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Doorakkers E, Lagergren J, Engstrand L, Brusselaers N
Gut 69 (6) 1149-1150 [2020-06-00; online 2019-05-21]
PubMed DOI Crossref
Recognition of synthetic polyanionic ligands underlies "spontaneous" reactivity of Vγ1 γδTCRs.
Dunst J, Glaros V, Englmaier L, ..., Kisielow J, Kreslavsky T
J Leukoc Biol 107 (6) 1033-1044 [2020-06-00; online 2020-01-13]
PubMed DOI Crossref
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Atabaki-Pasdar N, Ohlsson M, Viñuela A, ..., Pavo I, Franks PW
PLoS Med. 17 (6) e1003149 [2020-06-00; online 2020-06-19]
PubMed DOI Crossref
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Lorent JH, Levental KR, Ganesan L, ..., Lyman E, Levental I
Nat. Chem. Biol. 16 (6) 644-652 [2020-06-00; online 2020-05-04]
DDLS Fellow Erdinc Sezgin Milka Doktorova SciLifeLab Fellow
PubMed DOI Crossref
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Niemelä V, Salih A, Solea D, ..., Dahl N, Paucar M
Neurol Genet 6 (3) e426 [2020-06-00; online 2020-04-27]
PubMed DOI Crossref
No distinct microbiome signature of irritable bowel syndrome found in a Swedish random population.
Hugerth LW, Andreasson A, Talley NJ, ..., Agreus L, Engstrand L
Gut 69 (6) 1076-1084 [2020-06-00; online 2019-10-10]
DDLS Fellow Luisa Hugerth
PubMed DOI Crossref
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Brodin P
Hum. Genet. 139 (6-7) 795-799 [2020-06-00; online 2020-02-10]
PubMed DOI Crossref
Nanomedicine for improvement of dendritic cell-based cancer immunotherapy.
Hashemi V, Farhadi S, Ghasemi Chaleshtari M, ..., Ghalamfarsa G, Jadidi-Niaragh F
Int. Immunopharmacol. 83 (-) 106446 [2020-06-00; online 2020-03-31]
PubMed DOI Crossref
Multi-parametric single cell evaluation defines distinct drug responses in healthy hematologic cells that are retained in corresponding malignant cell types.
Majumder MM, Leppä AM, Hellesøy M, ..., Gjertsen BT, Heckman CA
Haematologica 105 (6) 1527-1538 [2020-06-00; online 2019-08-22]
PubMed DOI Crossref
Molecular atlas of the adult mouse brain.
Ortiz C, Navarro JF, Jurek A, ..., Lundeberg J, Meletis K
Sci Adv 6 (26) eabb3446 [2020-06-00; online 2020-06-26]
PubMed DOI Crossref
Mitochondrial genomes from Bronze Age Poland reveal genetic continuity from the Late Neolithic and additional genetic affinities with the steppe populations.
Juras A, Makarowicz P, Chyleński M, ..., Jakobsson M, Dabert M
Am. J. Phys. Anthropol. 172 (2) 176-188 [2020-06-00; online 2020-04-15]
PubMed DOI Crossref
Mending Fences: Na,K-ATPase signaling via Ca2+ in the maintenance of epithelium integrity.
Aperia A, Brismar H, Uhlén P
Cell Calcium 88 (-) 102210 [2020-06-00; online 2020-04-26]
PubMed DOI Crossref
Improvement in the Current Therapies for Hepatocellular Carcinoma Using a Systems Medicine Approach.
Ozcan M, Altay O, Lam S, ..., Boren J, Mardinoglu A
Adv Biosyst 4 (6) e2000030 [2020-06-00; online 2020-04-08]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Immediate Adaptation Analysis Implicates BCL6 as an EGFR-TKI Combination Therapy Target in NSCLC.
Zhou Tran Y, Minozada R, Cao X, ..., Seashore-Ludlow B, Orre LM
Mol. Cell Proteomics 19 (6) 928-943 [2020-06-00; online 2020-03-31]
PubMed DOI Crossref
Human papillomavirus prevalence and risk factors among HIV-negative and HIV-positive women residing in rural Eastern Cape, South Africa.
Taku O, Businge CB, Mdaka ML, ..., Williamson AL, Mbulawa ZZA
Int J Infect Dis 95 (-) 176-182 [2020-06-00; online 2020-02-27]
PubMed DOI Crossref
Helicobacter pylori eradication treatment and the risk of Barrett's esophagus and esophageal adenocarcinoma.
Doorakkers E, Lagergren J, Santoni G, Engstrand L, Brusselaers N
Helicobacter 25 (3) e12688 [2020-06-00; online 2020-03-16]
PubMed DOI Crossref
Germ-free and microbiota-associated mice yield small intestinal epithelial organoids with equivalent and robust transcriptome/proteome expression phenotypes.
Hausmann A, Russo G, Grossmann J, ..., Sellin ME, Hardt WD
Cell. Microbiol. 22 (6) e13191 [2020-06-00; online 2020-03-04]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Evaluation of a Hybrid Capture-Based Pan-Cancer Panel for Analysis of Treatment Stratifying Oncogenic Aberrations and Processes.
Kroeze LI, de Voer RM, Kamping EJ, ..., Grünberg K, Ligtenberg MJL
J Mol Diagn 22 (6) 757-769 [2020-06-00; online 2020-03-20]
PubMed DOI Crossref
Effects of chemical fractions from an oil sands end-pit lake on reproduction of fathead minnows.
Morandi G, Wiseman S, Sun C, Martin JW, Giesy JP
Chemosphere 249 (-) 126073 [2020-06-00; online 2020-02-01]
PubMed DOI Crossref
Dose and time effects of solar-simulated ultraviolet radiation on the in vivo human skin transcriptome.
Bustamante M, Hernandez-Ferrer C, Tewari A, ..., Nieuwenhuijsen M, Young AR
Br. J. Dermatol. 182 (6) 1458-1468 [2020-06-00; online 2019-11-27]
Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
DEqMS: A Method for Accurate Variance Estimation in Differential Protein Expression Analysis.
Zhu Y, Orre LM, Zhou Tran Y, ..., Anders S, Lehtiö J
Mol. Cell Proteomics 19 (6) 1047-1057 [2020-06-00; online 2020-03-23]
PubMed DOI Crossref
Balancing selection in Pattern Recognition Receptor signalling pathways is associated with gene function and pleiotropy in a wild rodent.
Lundberg M, Zhong X, Konrad A, Olsen RA, Råberg L
Mol. Ecol. 29 (11) 1990-2003 [2020-06-00; online 2020-06-03]
PubMed DOI Crossref
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Lorent JH, Levental KR, Ganesan L, ..., Lyman E, Levental I
Nat. Chem. Biol. 16 (6) 710 [2020-06-00; online 2020-05-18]
DDLS Fellow Erdinc Sezgin Milka Doktorova SciLifeLab Fellow
PubMed DOI Crossref
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Kell DB
Nat. Chem. Biol. 16 (6) 710 [2020-06-00; online 2020-04-10]
PubMed DOI Crossref
An immune gene expression signature distinguishes central nervous system metastases from primary tumours in non-small-cell lung cancer.
Tsakonas G, Lewensohn R, Botling J, ..., Hydbring P, Ekman S
Eur. J. Cancer 132 (-) 24-34 [2020-06-00; online 2020-04-20]
PubMed DOI Crossref
African population history: an ancient DNA perspective.
Vicente M, Schlebusch CM
Curr. Opin. Genet. Dev. 62 (-) 8-15 [2020-06-00; online 2020-06-18]
PubMed DOI Crossref
Activation of plasmacytoid dendritic cells and B cells with two structurally different Toll-like receptor 7 agonists.
Berggren O, Pucholt P, Amcoff C, Rönnblom L, Eloranta ML
Scand. J. Immunol. 91 (6) e12880 [2020-06-00; online 2020-04-13]
DOI Crossref
AB0206 CIRCULATING CENTROMERE PROTEIN F AUTOANTIBODIES FOR PREDICTING CLINICAL RESPONSE TO INFLIXIMAB IN RHEUMATOID ARTHRITIS
Lourido L, Ruiz-Romero C, Picchi F, ..., Nilsson P, Blanco FJ
Ann Rheum Dis 79 (-) 1403 [2020-06-00; online 2020-06-00]
PubMed DOI Crossref
A molecularly distinct subset of glioblastoma requires serum-containing media to establish sustainable bona fide glioblastoma stem cell cultures.
Maturi NP, Tan EJ, Xie Y, ..., Jiang Y, Uhrbom L
Glia 68 (6) 1228-1240 [2020-06-00; online 2019-12-23]
PubMed DOI Crossref
In silico Druggability Assessment of the NUDIX Hydrolase Protein Family as a Workflow for Target Prioritization.
Michel M, Homan EJ, Wiita E, ..., Helleday T, Warpman Berglund U
Front Chem 8 (-) 443 [2020-05-29; online 2020-05-29]
DOI Crossref
Novel heme-binding enables allosteric modulation in an ancient TIM-barrel glycosidase
Gamiz-Arco G, Gutierrez-Rus LI, Risso VA, ..., Gaucher EA, Sanchez-Ruiz JM
- - (-) - [2020-05-28; online 2020-05-28]
PubMed DOI Crossref
Intrinsic Dissolution Rate Profiling of Poorly Water-Soluble Compounds in Biorelevant Dissolution Media.
Teleki A, Nylander O, Bergström CAS
Pharmaceutics 12 (6) 493 [2020-05-28; online 2020-05-28]
Alexandra Teleki SciLifeLab Fellow
DOI Crossref
Cryo-EM Structure of Native Human Uromodulin, a Zona Pellucida Module Polymer
Stsiapanava A, Xu C, Brunati M, ..., Wu B, Jovine L
- - (-) - [2020-05-28; online 2020-05-28]
PubMed DOI Crossref
Shift in ecological strategy helps marginal populations of shepherd's purse (Capsella bursa-pastoris) to overcome a high genetic load.
Orsucci M, Milesi P, Hansen J, ..., Glémin S, Lascoux M
Proc. Biol. Sci. 287 (1927) 20200463 [2020-05-27; online 2020-05-20]
Pascal Milesi SciLifeLab Fellow
DOI Crossref
Sirtuin-1 Sensitive Lysine-136 Acetylation Drives Phase Separation and Pathological Aggregation of TDP-43
Morato JG, Hans F, von Zweydorf F, ..., Neumann M, Kahle PJ
- - (-) - [2020-05-26; online 2020-05-26]
SciLifeLab Fellow Simon Elsässer
DOI Crossref
GPSeq reveals the radial organization of chromatin in the cell nucleus
Custodio J, Kallas T, Girelli G, ..., Crosetto N, Bienko M
- - (-) - [2020-05-26; online 2020-05-26]
Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
Probing contacts of inhibitor locked in transition states in the catalytic triad of DENV2 type serine protease and its mutants by 1H, 19F and 15 N NMR spectroscopy.
Agback P, Woestenenk E, Agback T
BMC Mol Cell Biol 21 (1) 38 [2020-05-25; online 2020-05-25]
DOI Crossref
Energy efficiency and biological interactions define the core microbiome of deep oligotrophic groundwater
Mehrshad M, Lopez-Fernandez M, Sundh J, ..., Bertilsson S, Dopson M
- - (-) - [2020-05-25; online 2020-05-25]
PubMed DOI Crossref
LRIG1 gene copy number analysis by ddPCR and correlations to clinical factors in breast cancer.
Faraz M, Tellström A, Ardnor CE, ..., Hedman H, Ljuslinder I
BMC Cancer 20 (1) 459 [2020-05-24; online 2020-05-24]
PubMed DOI Crossref
Transcript isoform sequencing reveals widespread promoter-proximal transcriptional termination in Arabidopsis.
Thomas QA, Ard R, Liu J, ..., Pelechano V, Marquardt S
Nat Commun 11 (1) 2589 [2020-05-22; online 2020-05-22]
SciLifeLab Fellow
DOI Crossref
Peer Review Report For: A community proposal to integrate structural bioinformatics activities in ELIXIR (3D-Bioinfo Community) [version 1; peer review: 1 approved, 3 approved with reservations]
- - (-) - [2020-05-22; online 2020-05-22]
DOI Crossref
Genome-wide analysis identifies genetic effects on reproductive success and ongoing natural selection at the FADS locus
Mathieson I, Day FR, Barban N, ..., Mills MC, Perry JRB
- - (-) - [2020-05-22; online 2020-05-22]
DOI Crossref
An embryonic stem cell-specific heterochromatin state allows core histone exchange in the absence of DNA accessibility
Navarro C, Elsässer SJ
- - (-) - [2020-05-22; online 2020-05-22]
SciLifeLab Fellow Simon Elsässer
DOI Crossref
Peer Review Report For: A community proposal to integrate structural bioinformatics activities in ELIXIR (3D-Bioinfo Community) [version 1; peer review: 1 approved, 3 approved with reservations]
- - (-) - [2020-05-21; online 2020-05-21]
PubMed DOI Crossref
Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction.
Ntalla I, Weng LC, Cartwright JH, ..., Lubitz SA, Munroe PB
Nat Commun 11 (1) 2542 [2020-05-21; online 2020-05-21]
PubMed DOI Crossref
nucleAIzer: A Parameter-free Deep Learning Framework for Nucleus Segmentation Using Image Style Transfer.
Hollandi R, Szkalisity A, Toth T, ..., Smith K, Horvath P
Cell Syst 10 (5) 453-458.e6 [2020-05-20; online 2020-05-07]
DOI Crossref
Silica particles trigger the production of exopolysaccharides in harsh environment plant growth-promoting rhizobacteria and increase their ability to enhance drought tolerance
Fetsiukh A, Conrad J, Bergquist J, Ayele F, Timmusk S
- - (-) - [2020-05-20; online 2020-05-20]
PubMed DOI Crossref
Opposing spatial trends in methylmercury and total mercury along a peatland chronosequence trophic gradient.
Wang B, Nilsson MB, Eklöf K, ..., Skyllberg U, Bishop K
Sci. Total Environ. 718 (-) 137306 [2020-05-20; online 2020-02-13]
PubMed DOI Crossref
Integration of whole-body [18F]FDG PET/MRI with non-targeted metabolomics can provide new insights on tissue-specific insulin resistance in type 2 diabetes.
Diamanti K, Visvanathar R, Pereira MJ, ..., Wadelius C, Ahlström H
Sci Rep 10 (1) 8343 [2020-05-20; online 2020-05-20]
PubMed DOI Crossref
Integrating the "Immunome" in the Stratification of Myelodysplastic Syndromes and Future Clinical Trial Design.
Winter S, Shoaie S, Kordasti S, Platzbecker U
J Clin Oncol 38 (15) 1723-1735 [2020-05-20; online 2020-02-14]
Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
z-STED Imaging and Spectroscopy to Investigate Nanoscale Membrane Structure and Dynamics.
Barbotin A, Urbančič I, Galiani S, ..., Booth M, Sezgin E
Biophys. J. 118 (10) 2448-2457 [2020-05-19; online 2020-04-16]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
The Archaeal Roots of the Eukaryotic Dynamic Actin Cytoskeleton.
Stairs CW, Ettema TJG
Curr. Biol. 30 (10) R521-R526 [2020-05-18; online 2020-05-20]
PubMed DOI Crossref
Multi-HLA class II tetramer analyses of citrulline-reactive T cells and early treatment response in rheumatoid arthritis.
Gerstner C, Turcinov S, Hensvold AH, ..., van Baarsen LGM, Malmström V
BMC Immunol. 21 (1) 27 [2020-05-18; online 2020-05-18]
PubMed DOI Crossref
Behavioral Characterization of dmrt3a Mutant Zebrafish Reveals Crucial Aspects of Vertebrate Locomotion through Phenotypes Related to Acceleration.
Del Pozo A, Manuel R, Iglesias Gonzalez AB, ..., Kullander K, Boije H
eNeuro 7 (3) - [2020-05-18; online 2020-05-18]
DOI Crossref
Profiling of small non-coding RNAs across cellular and biofluid compartments: implications for multiple sclerosis immunopathology
Zheleznyakova GY, Piket E, Needhamsen M, ..., Piehl F, Jagodic M
- - (-) - [2020-05-16; online 2020-05-16]
PubMed DOI Crossref
Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson's disease.
Tiklová K, Nolbrant S, Fiorenzano A, ..., Perlmann T, Parmar M
Nat Commun 11 (1) 2434 [2020-05-15; online 2020-05-15]
DOI Crossref
A freshwater radiation of diplonemids
Mukherjee I, Salcher MM, Andrei AŞ, ..., Šimek K, Ghai R
- - (-) - [2020-05-15; online 2020-05-15]
PubMed DOI Crossref
Molecular Docking Studies of Royleanone Diterpenoids from Plectranthus spp. as P-Glycoprotein Inhibitors.
Isca VMS, Ferreira RJ, Garcia C, ..., Afonso CAM, Rijo P
ACS Med. Chem. Lett. 11 (5) 839-845 [2020-05-14; online 2020-03-12]
PubMed DOI Crossref
Targeting tumor vulnerabilities associated with loss of heterozygosity.
Rendo V, Stoimenov I, Sjöblom T
Mol Cell Oncol 7 (4) 1759390 [2020-05-13; online 2020-05-13]
PubMed DOI Crossref
Proteomic profiles before and during weight loss: Results from randomized trial of dietary intervention.
Figarska SM, Rigdon J, Ganna A, ..., Gardner CD, Ingelsson E
Sci Rep 10 (1) 7913 [2020-05-13; online 2020-05-13]
PubMed DOI Crossref
In Situ Sequencing: A High-Throughput, Multi-Targeted Gene Expression Profiling Technique for Cell Typing in Tissue Sections.
Hilscher MM, Gyllborg D, Yokota C, Nilsson M
Methods in molecular biology (Clifton, N.J.) 2148 (-) 313-329 [2020-05-13; online 2020-05-13]
PubMed DOI Crossref
Theoretical Infrared Spectra: Quantitative Similarity Measures and Force Fields.
Henschel H, Andersson AT, Jespers W, Mehdi Ghahremanpour M, van der Spoel D
J Chem Theory Comput 16 (5) 3307-3315 [2020-05-12; online 2020-04-23]
PubMed DOI Crossref
Quantitative analysis of amino acid metabolism in liver cancer links glutamate excretion to nucleotide synthesis.
Nilsson A, Haanstra JR, Engqvist M, ..., Teusink B, Nielsen J
Proc. Natl. Acad. Sci. U.S.A. 117 (19) 10294-10304 [2020-05-12; online 2020-04-27]
Avlant Nilsson DDLS Fellow
PubMed DOI Crossref
Blood-derived biomarkers correlate with clinical progression in Duchenne muscular dystrophy.
Strandberg K, Ayoglu B, Roos A, ..., Nilsson P, Szigyarto CA
J Neuromuscul Dis 7 (3) 231-246 [2020-05-12; online 2020-05-12]
DOI Crossref
A chemical screen identifies a link between lipid metabolism and mRNA translation
Corman A, Kanellis DC, Häggblad M, ..., Carreras-Puigvert J, Fernandez-Capetillo O
- - (-) - [2020-05-11; online 2020-05-11]
DOI Crossref
Lactone monomers obtained by enzyme catalysis and their use in reversible thermoresponsive networks
Farhat W, Biundo A, Stamm A, Malmström E, Syrén P
J of Applied Polymer Sci 137 (18) - [2020-05-10; online 2020-01-14]
PubMed DOI Crossref
Histidyl-Proline Diketopiperazine Isomers as Multipotent Anti-Alzheimer Drug Candidates.
Turkez H, Cacciatore I, Arslan ME, ..., Di Stefano A, Mardinoglu A
Biomolecules 10 (5) 737 [2020-05-09; online 2020-05-09]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Epoxylathyrane Derivatives as MDR-Selective Compounds for Disabling Multidrug Resistance in Cancer.
Reis MA, Matos AM, Duarte N, ..., Lage H, Ferreira MU
Front. Pharmacol. 11 (-) 599 [2020-05-08; online 2020-05-08]
DOI Crossref
“A Proteogenomic workflow reveals distinct molecular phenotypes related to breast cancer appearance”
De Marchi T, Pyl PT, Sjöstrom M, ..., Malmström L, Niméus E
- - (-) - [2020-05-07; online 2020-05-07]
DOI Crossref
Optimal protocols for sequence-based characterization of the human vaginal microbiome
Hugerth LW, Pereira M, Zha Y, ..., Schuppe-Koistinen I, Engstrand L
- - (-) - [2020-05-07; online 2020-05-07]
DDLS Fellow Luisa Hugerth
DOI Crossref
MEIS-WNT5A axis regulates development of 4 th ventricle choroid plexus
Kaiser K, Jang A, Lun MP, ..., Lehtinen MK, Bryja V
- - (-) - [2020-05-07; online 2020-05-07]
DOI Crossref
Identification of 370 genetic loci for age at first sex and birth linked to externalising behaviour
Mills MC, Tropf FC, Brazel DM, ..., Barban N, Day FR
- - (-) - [2020-05-07; online 2020-05-07]
PubMed DOI Crossref
Human proteins incorporated into tick-borne encephalitis virus revealed by in situ proximity ligation.
Ikebuchi R, Isaac AW, Yoshii K, ..., Landegren U, Kamali-Moghaddam M
Biochem. Biophys. Res. Commun. 525 (3) 714-719 [2020-05-07; online 2020-03-03]
PubMed DOI Crossref
Feasibility of Imaging EpCAM Expression in Ovarian Cancer Using Radiolabeled DARPin Ec1.
Vorobyeva A, Konovalova E, Xu T, ..., Tolmachev V, Deyev S
Int J Mol Sci 21 (9) - [2020-05-07; online 2020-05-07]
DOI Crossref
Malignant Schwann cell precursors mediate intratumoral plasticity in human neuroblastoma
Olsen TK, Otte J, Mei S, ..., Kharchenko PV, Baryawno N
- - (-) - [2020-05-05; online 2020-05-05]
PubMed DOI Crossref
A progressive and complex clinical course in two family members with ERF-related craniosynostosis: a case report.
Körberg I, Nowinski D, Bondeson ML, ..., Kölby L, Stattin EL
BMC Med. Genet. 21 (1) 90 [2020-05-05; online 2020-05-05]
PubMed DOI Crossref
Glycosylation Tunes Neuroserpin Physiological and Pathological Properties.
Visentin C, Broggini L, Sala BM, ..., Achour A, Ricagno S
Int J Mol Sci 21 (9) - [2020-05-03; online 2020-05-03]
PubMed DOI Crossref
Rare variants in dynein heavy chain genes in two individuals with situs inversus and developmental dyslexia: a case report.
Bieder A, Einarsdottir E, Matsson H, ..., Kere J, Tapia-Páez I
BMC Med. Genet. 21 (1) 87 [2020-05-01; online 2020-05-01]
PubMed DOI Crossref
Predicting resolution and image quality in RESOLFT and other point scanning microscopes [Invited].
Bodén A, Casas Moreno X, Cooper BK, York AG, Testa I
Biomed Opt Express 11 (5) 2313-2327 [2020-05-01; online 2020-04-02]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
National Cancer Institute Think-Tank Meeting Report on Proteomic Cartography and Biomarkers at the Single-Cell Level: Interrogation of Premalignant Lesions.
Kagan J, Moritz RL, Mazurchuk R, ..., Smith RD, Srivastava S
J. Proteome Res. 19 (5) 1900-1912 [2020-05-01; online 2020-04-02]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
MaRe: Processing Big Data with application containers on Apache Spark.
Capuccini M, Dahlö M, Toor S, Spjuth O
Gigascience 9 (5) - [2020-05-01; online 2020-05-06]
DOI Crossref
Genomic epidemiology of Campylobacter jejuni associated with asymptomatic pediatric infection in the Peruvian Amazon
Pascoe B, Schiaffino F, Murray S, ..., Kosek MN, Sheppard SK
- - (-) - [2020-05-01; online 2020-05-01]
PubMed DOI Crossref
Extracellular vesicles from mast cells induce mesenchymal transition in airway epithelial cells.
Yin Y, Shelke GV, Lässer C, Brismar H, Lötvall J
Respir. Res. 21 (1) 101 [2020-05-01; online 2020-05-01]
DOI Crossref
Dysregulation in mTOR/HIF-1 signaling identified by proteo-transcriptomics of SARS-CoV-2 infected cells
Appelberg S, Gupta S, Ambikan AT, ..., Mirazimi A, Neogi U
- - (-) - [2020-05-01; online 2020-05-01]
PubMed DOI Crossref
Differential Expression of Immune Genes between Two Closely Related Beetle Species with Different Immunocompetence following Attack by Asecodes parviclava.
Yang X, Fors L, Slotte T, ..., Wheat CW, Hambäck PA
Genome Biol Evol 12 (5) 522-534 [2020-05-01; online 2020-04-14]
SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Whole-genome sequencing reveals complex chromosome rearrangement disrupting NIPBL in infant with Cornelia de Lange syndrome.
Plesser Duvdevani M, Pettersson M, Eisfeldt J, ..., Lindstrand A, Harel T
Am. J. Med. Genet. A 182 (5) 1143-1151 [2020-05-00; online 2020-03-03]
PubMed DOI Crossref
Tuning antiviral CD8 T-cell response via proline-altered peptide ligand vaccination.
Duru AD, Sun R, Allerbring EB, ..., Turner SJ, Achour A
PLoS Pathog 16 (5) e1008244 [2020-05-00; online 2020-05-04]
PubMed DOI Crossref
The utility of artificial intelligence in the assessment of prostate pathology.
Egevad L, Ström P, Kartasalo K, ..., Delahunt B, Eklund M
Histopathology 76 (6) 790-792 [2020-05-00; online 2020-05-14]
DDLS Fellow Kimmo Kartasalo
PubMed DOI Crossref
TGFβ and EGF signaling orchestrates the AP-1- and p63 transcriptional regulation of breast cancer invasiveness.
Sundqvist A, Vasilaki E, Voytyuk O, ..., Ten Dijke P, van Dam H
Oncogene 39 (22) 4436-4449 [2020-05-00; online 2020-04-29]
PubMed DOI Crossref
TARP is an immunotherapeutic target in acute myeloid leukemia expressed in the leukemic stem cell compartment.
Depreter B, Weening KE, Vandepoele K, ..., Lammens T, Philippé J
Haematologica 105 (5) 1306-1316 [2020-05-00; online 2019-08-01]
PubMed DOI Crossref
SweHLA: the high confidence HLA typing bio-resource drawn from 1000 Swedish genomes.
Nordin J, Ameur A, Lindblad-Toh K, Gyllensten U, Meadows JRS
Eur. J. Hum. Genet. 28 (5) 627-635 [2020-05-00; online 2019-12-16]
PubMed DOI Crossref
Structural insights into influenza A virus ribonucleoproteins reveal a processive helical track as transcription mechanism.
Coloma R, Arranz R, de la Rosa-Trevín JM, ..., Ortín J, Martín-Benito J
Nat. Microbiol 5 (5) 727-734 [2020-05-00; online 2020-03-09]
PubMed DOI Crossref
Serglycin activates pro-tumorigenic signaling and controls glioblastoma cell stemness, differentiation and invasive potential.
Manou D, Bouris P, Kletsas D, ..., Karamanos NK, Theocharis AD
Matrix Biol Plus 6-7 (-) 100033 [2020-05-00; online 2020-03-11]
PubMed DOI Crossref
Salmonella Typhimurium discreet-invasion of the murine gut absorptive epithelium.
Fattinger SA, Böck D, Di Martino ML, ..., Hardt WD, Sellin ME
PLoS Pathog 16 (5) e1008503 [2020-05-00; online 2020-05-04]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
RNA at DNA Double-Strand Breaks: The Challenge of Dealing with DNA:RNA Hybrids.
Domingo-Prim J, Bonath F, Visa N
Bioessays 42 (5) e1900225 [2020-05-00; online 2020-02-27]
PubMed DOI Crossref
Next-Generation Sequencing Reveals Differential Responses to Acute versus Long-Term Exposures to Graphene Oxide in Human Lung Cells.
Mukherjee SP, Gupta G, Klöditz K, ..., Kostarelos K, Fadeel B
Small 16 (21) e1907686 [2020-05-00; online 2020-03-29]
PubMed DOI Crossref
Managing COVID-19 in the oncology clinic and avoiding the distraction effect.
Cortiula F, Pettke A, Bartoletti M, Puglisi F, Helleday T
Ann. Oncol. 31 (5) 553-555 [2020-05-00; online 2020-03-19]
PubMed DOI Crossref
Intestinal epithelial NAIP/NLRC4 restricts systemic dissemination of the adapted pathogen Salmonella Typhimurium due to site-specific bacterial PAMP expression.
Hausmann A, Böck D, Geiser P, ..., Sellin ME, Hardt WD
Mucosal Immunol 13 (3) 530-544 [2020-05-00; online 2020-01-17]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Increased iron absorption in patients with chronic heart failure and iron deficiency.
Cabrera CC, Ekström M, Linde C, ..., Tornvall P, Lyngå P
J Card Fail 26 (5) 440-443 [2020-05-00; online 2020-03-09]
PubMed DOI Crossref
Extra-pair paternity as a strategy to reduce the costs of heterospecific reproduction? Insights from the crow hybrid zone.
Knief U, Bossu CM, Wolf JBW
J Evol Biol 33 (5) 727-733 [2020-05-00; online 2020-03-16]
PubMed DOI Crossref
Early Childhood Antibiotic Treatment for Otitis Media and Other Respiratory Tract Infections Is Associated With Risk of Type 1 Diabetes: A Nationwide Register-Based Study With Sibling Analysis.
Wernroth ML, Fall K, Svennblad B, ..., Almqvist C, Fall T
Diabetes Care 43 (5) 991-999 [2020-05-00; online 2020-03-04]
PubMed DOI Crossref
Duchenne Muscular Dystrophy: recent advances in protein biomarkers and the clinical application.
Al-Khalili Szigyarto C
Expert Rev Proteomics 17 (5) 365-375 [2020-05-00; online 2020-07-28]
DOI Crossref
Does browning‐induced light limitation reduce fish body growth through shifts in prey composition or reduced foraging rates?
van Dorst RM, Gårdmark A, Svanbäck R, Huss M
Freshw Biol 65 (5) 947-959 [2020-05-00; online 2020-01-30]
PubMed DOI Crossref
Comprehensive chemical proteomics for target deconvolution of the redox active drug auranofin.
Saei AA, Gullberg H, Sabatier P, ..., Arnér ESJ, Zubarev RA
Redox Biol 32 (-) 101491 [2020-05-00; online 2020-03-03]
PubMed DOI Crossref
Analysis of DNA methylation patterns in the tumor immune microenvironment of metastatic melanoma.
Mitra S, Lauss M, Cabrita R, ..., Brown KM, Jönsson G
Mol Oncol 14 (5) 933-950 [2020-05-00; online 2020-03-21]
PubMed DOI Crossref
Active sulfur cycling in the terrestrial deep subsurface.
Bell E, Lamminmäki T, Alneberg J, ..., Frutschi M, Bernier-Latmani R
ISME J 14 (5) 1260-1272 [2020-05-00; online 2020-02-11]
PubMed DOI Crossref
Interactive proteogenomic exploration of response to Fusarium head blight in oat varieties with different resistance.
Willforss J, Leonova S, Tillander J, ..., Chawade A, Levander F
J Proteomics 218 (-) 103688 [2020-04-30; online 2020-02-14]
DOI Crossref
Visualizing drug inhibitor binding interactions using microcrystal electron diffraction
Clabbers MTB, Fisher SZ, Coinçon M, Zou X, Xu H
- - (-) - [2020-04-29; online 2020-04-29]
PubMed DOI Crossref
SpatialCPie: an R/Bioconductor package for spatial transcriptomics cluster evaluation.
Bergenstråhle J, Bergenstråhle L, Lundeberg J
BMC Bioinformatics 21 (1) 161 [2020-04-29; online 2020-04-29]
PubMed DOI Crossref
Interactions of the Lysosomotropic Detergent O-Methyl-Serine Dodecylamide Hydrochloride (MSDH) with Lipid Bilayer Membranes-Implications for Cell Toxicity.
Villamil Giraldo AM, Eriksson I, Wennmalm S, ..., Ederth T, Öllinger K
Int J Mol Sci 21 (9) - [2020-04-29; online 2020-04-29]
DOI Crossref
Bistability in oxidative stress response determines the migration behavior of phytoplankton in turbulence
Carrara F, Sengupta A, Behrendt L, Vardi A, Stocker R
- - (-) - [2020-04-29; online 2020-04-29]
Lars Behrendt SciLifeLab Fellow
PubMed DOI Crossref
The microcircuits of striatum in silico.
Hjorth JJJ, Kozlov A, Carannante I, ..., Hellgren Kotaleski J, Grillner S
Proc. Natl. Acad. Sci. U.S.A. 117 (17) 9554-9565 [2020-04-28; online 2020-04-22]
DOI Crossref
The N-Terminal Helix-Turn-Helix Motif of Transcription Factors MarA and Rob Drives DNA Recognition
Corbella M, Liao Q, Kasson PM, Kamerlin SCL
- - (-) - [2020-04-27; online 2020-04-27]
DOI Crossref
The genetic variation of lactase persistence alleles in northeast Africa
Hollfelder N, Babiker H, Granehäll L, Schlebusch CM, Jakobsson M
- - (-) - [2020-04-24; online 2020-04-24]
DOI Crossref
Parallel factor analysis enables quantification and identification of highly-convolved data independent-acquired protein spectra
Buric F, Zrimec J, Zelezniak A
- - (-) - [2020-04-23; online 2020-04-23]
Aleksej Zelezniak SciLifeLab Fellow
PubMed DOI Crossref
Optimization of Tetrahydroindazoles as Inhibitors of Human Dihydroorotate Dehydrogenase and Evaluation of Their Activity and In Vitro Metabolic Stability.
Popova G, Ladds MJGW, Johansson L, ..., Yngve U, Lain S
J Med Chem 63 (8) 3915-3934 [2020-04-23; online 2020-04-08]
PubMed DOI Crossref
Evolution of Angiotensin Peptides and Peptidomimetics as Angiotensin II Receptor Type 2 (AT2) Receptor Agonists.
Vasile S, Hallberg A, Sallander J, ..., Åqvist J, Gutiérrez-de-Terán H
Biomolecules 10 (4) - [2020-04-23; online 2020-04-23]
PubMed DOI Crossref
Tumor endothelial ELTD1 as a predictive marker for treatment of renal cancer patients with sunitinib.
Niinivirta M, Georganaki M, Enblad G, ..., Dimberg A, Ullenhag GJ
BMC Cancer 20 (1) 339 [2020-04-22; online 2020-04-22]
PubMed DOI Crossref
A community proposal to integrate structural bioinformatics activities in ELIXIR (3D-Bioinfo Community).
Orengo C, Velankar S, Wodak S, ..., Salminen T, Schneider B
F1000Res 9 (-) - [2020-04-22; online 2020-04-22]
PubMed DOI Crossref
Vascular permeability in retinopathy is regulated by VEGFR2 Y949 signaling to VE-cadherin.
Smith RO, Ninchoji T, Gordon E, ..., Kvanta A, Claesson-Welsh L
Elife 9 (-) - [2020-04-21; online 2020-04-21]
DOI Crossref
Integrated analyses of single-cell atlases reveal age, gender, and smoking status associations with cell type-specific expression of mediators of SARS-CoV-2 viral entry and highlights inflammatory programs in putative target cells
Muus C, Luecken MD, Eraslan G, ..., Zhao W, Ziegler CGK
- - (-) - [2020-04-20; online 2020-04-20]
PubMed DOI Crossref
Tumor-Targeted Delivery of the p53-Activating Peptide VIP116 with PEG-Stabilized Lipodisks.
Lundsten S, Hernández VA, Gedda L, ..., Edwards K, Nestor M
Nanomaterials (Basel) 10 (4) - [2020-04-19; online 2020-04-19]
PubMed DOI Crossref
Broad Host Range of SARS-CoV-2 Predicted by Comparative and Structural Analysis of ACE2 in Vertebrates.
Damas J, Hughes GM, Keough KC, ..., Karlsson EK, Lewin HA
bioRxiv - (-) - [2020-04-18; online 2020-04-18]
PubMed DOI Crossref
Genome-Scale Metabolic Modeling of Glioblastoma Reveals Promising Targets for Drug Development.
Larsson I, Uhlén M, Zhang C, Mardinoglu A
Front Genet 11 (-) 381 [2020-04-17; online 2020-04-17]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Estimating the impact of mobility patterns on COVID-19 infection rates in 11 European countries
Bryant P, Elofsson A
medRxiv - (-) - [2020-04-17; online 2020-04-17]
DDLS Fellow Patrick Bryant
PubMed DOI Crossref
Whole-genome genotyping and resequencing reveal the association of a deletion in the complex interferon alpha gene cluster with hypothyroidism in dogs.
Bianchi M, Rafati N, Karlsson Å, ..., Lindblad-Toh K, Rosengren Pielberg G
BMC Genomics 21 (1) 307 [2020-04-16; online 2020-04-16]
PubMed DOI Crossref
Enhancing the therapeutic effects of in vitro targeted radionuclide therapy of 3D multicellular tumor spheroids using the novel stapled MDM2/X-p53 antagonist PM2.
Mortensen ACL, Morin E, Brown CJ, Lane DP, Nestor M
EJNMMI Res 10 (1) 38 [2020-04-16; online 2020-04-16]
DOI Crossref
Intervention strategies against COVID-19 and their estimated impact on Swedish healthcare capacity
Gardner JM, Willem L, Van Der Wijngaart W, ..., Brusselaers N, Kasson P
- - (-) - [2020-04-15; online 2020-04-15]
PubMed DOI Crossref
Increased burden of ultra-rare structural variants localizing to boundaries of topologically associated domains in schizophrenia.
Halvorsen M, Huh R, Oskolkov N, ..., Sullivan PF, Szatkiewicz JP
Nat Commun 11 (1) 1842 [2020-04-15; online 2020-04-15]
PubMed DOI Crossref
High photon count rates improve the quality of super-resolution fluorescence fluctuation spectroscopy.
Schneider F, Hernandez-Varas P, Christoffer Lagerholm B, ..., Eggeling C, Urbančič I
J. Phys. D: Appl. Phys. 53 (16) 164003 [2020-04-15; online 2020-02-13]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Functional and genomic characterization of three novel cell lines derived from a metastatic gallbladder cancer tumor.
García P, Bizama C, Rosa L, ..., Lagos M, Roa JC
Biol Res 53 (1) 13 [2020-04-15; online 2020-04-15]
PubMed DOI Crossref
Automation of Spatial Transcriptomics library preparation to enable rapid and robust insights into spatial organization of tissues.
Berglund E, Saarenpää S, Jemt A, ..., Lundeberg J, Giacomello S
BMC Genomics 21 (1) 298 [2020-04-15; online 2020-04-15]
PubMed DOI Crossref
Adaptive Resetting of Tuberoinfundibular Dopamine (TIDA) Network Activity during Lactation in Mice.
Thörn Pérez C, Ferraris J, van Lunteren JA, ..., Iglesias MJ, Broberger C
J. Neurosci. 40 (16) 3203-3216 [2020-04-15; online 2020-03-24]
DOI Crossref
Precise triggering and chemical control of single-virus fusion within endosomes
Haldar S, Okamoto K, Kasson PM
- - (-) - [2020-04-13; online 2020-04-13]
PubMed DOI Crossref
Involvement of Heparan Sulfate and Heparanase in Neural Development and Pathogenesis of Brain Tumors.
Xiong A, Spyrou A, Forsberg-Nilsson K
Springer 1221 (-) 365-403 [2020-04-11; online 2020-04-11]
PubMed DOI Crossref
Implications of Heparan Sulfate and Heparanase in Amyloid Diseases.
Li JP, Zhang X
Springer 1221 (-) 631-645 [2020-04-11; online 2020-04-11]
PubMed DOI Crossref
The European Research Network on Signal Transduction (ERNEST): Toward a Multidimensional Holistic Understanding of G Protein-Coupled Receptor Signaling.
Sommer ME, Selent J, Carlsson J, ..., Waldhoer M, Kolb P
ACS pharmacology & translational science 3 (2) 361-370 [2020-04-10; online 2020-03-31]
Jens Carlsson SciLifeLab Fellow
PubMed DOI Crossref
MutT homologue 1 (MTH1) removes N6-methyl-dATP from the dNTP pool.
Scaletti ER, Vallin KS, Bräutigam L, ..., Stenmark P, Jemth AS
J Biol Chem 295 (15) 4761-4772 [2020-04-10; online 2020-03-06]
DOI Crossref
Multi-HLA class II tetramer analyses of citrulline-reactive T cells and early treatment response in rheumatoid arthritis
Gerstner C, Turcinov S, Hensvold AH, ..., Baarsen LGMv, Malmström V
- - (-) - [2020-04-10; online 2020-04-10]
PubMed DOI Crossref
The in vitro cytotoxic, genotoxic, and oxidative damage potentials of the oral artificial sweetener aspartame on cultured human blood cells.
Çadirci K, Özdemir Tozlu Ö, Türkez H, Mardinoğlu A
Turk J Med Sci 50 (2) 448-454 [2020-04-09; online 2020-04-09]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
A New Census of Protein Tandem Repeats and Their Relationship with Intrinsic Disorder.
Delucchi M, Schaper E, Sachenkova O, Elofsson A, Anisimova M
Genes (Basel) 11 (4) - [2020-04-09; online 2020-04-09]
DOI Crossref
Characterization of the nuclear and cytosolic transcriptomes in human brain tissue reveals new insights into the subcellular distribution of RNA transcripts
Zaghlool A, Niazi A, Björklund ÅK, ..., Ameur A, Feuk L
- - (-) - [2020-04-08; online 2020-04-08]
PubMed DOI Crossref
Role of DNA Damage Response in Suppressing Malignant Progression of Chronic Myeloid Leukemia and Polycythemia Vera: Impact of Different Oncogenes.
Stetka J, Gursky J, Liñan Velasquez J, ..., Bartek J, Divoky V
Cancers (Basel) 12 (4) - [2020-04-07; online 2020-04-07]
DOI Crossref
Deep learning models for lipid-nanoparticle-based drug delivery
Harrison PJ, Wieslander H, Sabirsh A, ..., Wählby C, Spjuth O
- - (-) - [2020-04-07; online 2020-04-07]
PubMed DOI Crossref
Building blocks are synthesized on demand during the yeast cell cycle.
Campbell K, Westholm J, Kasvandik S, ..., Mormino M, Nielsen J
Proc. Natl. Acad. Sci. U.S.A. 117 (14) 7575-7583 [2020-04-07; online 2020-03-25]
PubMed DOI Crossref
c-Src controls stability of sprouting blood vessels in the developing retina independently of cell-cell adhesion through focal adhesion assembly.
Schimmel L, Fukuhara D, Richards M, ..., Claesson-Welsh L, Gordon E
Development 147 (7) - [2020-04-06; online 2020-04-06]
PubMed DOI Crossref
Protein Contact Map Prediction Based on ResNet and DenseNet.
Li Z, Lin Y, Elofsson A, Yao Y
Biomed Res Int 2020 (-) 7584968 [2020-04-06; online 2020-04-06]
DOI Crossref
Genomic evaluation of circulating proteins for drug target characterisation and precision medicine
Folkersen L, Gustafsson S, Wang Q, ..., Ingelsson E, Mälarstig A
- - (-) - [2020-04-06; online 2020-04-06]
DOI Crossref
Enhancing a De Novo Enzyme Activity by Computationally-Focused, Ultra-Low-Throughput Sequence Screening
Risso VA, Romero-Rivera A, Gutierrez-Rus LI, ..., Sanchez Ruiz JM, Kamerlin SCL
- - (-) - [2020-04-06; online 2020-04-06]
DOI Crossref
Building an International Consortium for Tracking Coronavirus Health Status
Segal E, Zhang F, Lin X, ..., Vilo J, Wilmes P
- - (-) - [2020-04-06; online 2020-04-06]
PubMed DOI Crossref
Shifts in mercury methylation across a peatland chronosequence: From sulfate reduction to methanogenesis and syntrophy.
Hu H, Wang B, Bravo AG, ..., Nilsson MB, Bertilsson S
J Hazard Mater 387 (-) 121967 [2020-04-05; online 2019-12-23]
DOI Crossref
Abundantly expressed class of non-coding RNAs conserved through the multicellular evolution of dictyostelid social amoebae
Kjellin J, Avesson L, Reimegård J, ..., Schaap P, Söderbom F
- - (-) - [2020-04-05; online 2020-04-05]
DOI Crossref
Direct Electrical Detection of sub-aM DNA Concentrations
Guo M, Madaboosi N, Neumann F, Nilsson M, van der Wijngaart W
- - (-) - [2020-04-04; online 2020-04-04]
DOI Crossref
The protein expression profile of ACE2 in human tissues
Hikmet F, Méar L, Edvinsson Å, ..., Uhlén M, Lindskog C
- - (-) - [2020-04-03; online 2020-04-03]
PubMed DOI Crossref
Pooled CRISPRi screening of the cyanobacterium Synechocystis sp PCC 6803 for enhanced industrial phenotypes.
Yao L, Shabestary K, Björk SM, ..., Jahn M, Hudson EP
Nat Commun 11 (1) 1666 [2020-04-03; online 2020-04-03]
Paul Hudson SciLifeLab Fellow
DOI Crossref
Guidelines for curriculum and course development in higher education and training
Tractenberg RE, Lindvall JM, Attwood T, Via A
- - (-) - [2020-04-03; online 2020-04-03]
DOI Crossref
Bayesian genome scale modelling identifies thermal determinants of yeast metabolism
Li G, Hu Y, Wang H, ..., Zrimec J, Nielsen J
- - (-) - [2020-04-02; online 2020-04-02]
Aleksej Zelezniak SciLifeLab Fellow
PubMed DOI Crossref
Author Correction: The GenTree Dendroecological Collection, tree-ring and wood density data from seven tree species across Europe.
Martínez-Sancho E, Slámová L, Morganti S, ..., Westin J, Fonti P
Sci Data 7 (1) 114 [2020-04-02; online 2020-04-02]
PubMed DOI Crossref
Thermal Proteome Profiling Identifies Oxidative-Dependent Inhibition of the Transcription of Major Oncogenes as a New Therapeutic Mechanism for Select Anticancer Compounds.
Peuget S, Zhu J, Sanz G, ..., Zubarev R, Selivanova G
Cancer Res. 80 (7) 1538-1550 [2020-04-01; online 2020-02-04]
PubMed DOI Crossref
Paralogization and New Protein Architectures in Planctomycetes Bacteria with Complex Cell Structures.
Mahajan M, Yee B, Hägglund E, ..., Fuerst JA, Andersson SGE
Mol. Biol. Evol. 37 (4) 1020-1040 [2020-04-01; online 2019-12-07]
PubMed DOI Crossref
Lung developmental arrest caused by PDGF-A deletion: consequences for the adult mouse lung.
Gouveia L, Kraut S, Hadzic S, ..., Betsholtz C, Andrae J
Am J Physiol Lung Cell Mol Physiol 318 (4) L831-L843 [2020-04-01; online 2020-03-18]
PubMed DOI Crossref
Development of basic building blocks for cryo-EM: the emcore and emvis software libraries.
de la Rosa-Trevín JM, Hernández Viga PA, Otón J, Lindahl E
Acta Crystallogr D Struct Biol 76 (Pt 4) 350-356 [2020-04-01; online 2020-03-31]
PubMed DOI Crossref
Author Correction: Mutational and putative neoantigen load predict clinical benefit of adoptive T cell therapy in melanoma.
Lauss M, Donia M, Harbst K, ..., Svane IM, Jönsson G
Nat Commun 11 (1) 1714 [2020-04-01; online 2020-04-01]
DOI Crossref
Weakly-Supervised Prediction of Cell Migration Modes in Confocal Microscopy Images Using Bayesian Deep Learning
Gupta A, Larsson V, Matuszewski D, Stromblad S, Wahlby C
- - (-) 1626-1629 [2020-04-00; online 2020-04-00]
PubMed DOI Crossref
Tumour heterogeneity and the evolutionary trade-offs of cancer.
Hausser J, Alon U
Nat. Rev. Cancer 20 (4) 247-257 [2020-04-00; online 2020-02-24]
Jean Hausser SciLifeLab Fellow
DOI Crossref
Transcriptome-Supervised Classification of Tissue Morphology Using Deep Learning
Andersson A, Partel G, Solorzano L, Wahlby C
- - (-) 1630-1633 [2020-04-00; online 2020-04-00]
PubMed DOI Crossref
Thrombo-Inflammation in Cardiovascular Disease: An Expert Consensus Document from the Third Maastricht Consensus Conference on Thrombosis.
d'Alessandro E, Becker C, Bergmeier W, ..., Ten Cate H, Scientific Reviewer Committee
Thromb. Haemost. 120 (4) 538-564 [2020-04-00; online 2020-04-14]
PubMed DOI Crossref
The role of physical activity in metabolic homeostasis before and after the onset of type 2 diabetes: an IMI DIRECT study.
Koivula RW, Atabaki-Pasdar N, Giordano GN, ..., Franks PW, IMI DIRECT Consortium
Diabetologia 63 (4) 744-756 [2020-04-00; online 2020-01-30]
PubMed DOI Crossref
The acute effect of metabolic cofactor supplementation: a potential therapeutic strategy against non-alcoholic fatty liver disease.
Zhang C, Bjornson E, Arif M, ..., Borén J, Mardinoglu A
Mol Syst Biol 16 (4) e9495 [2020-04-00; online 2020-04-28]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Simultaneous mass spectrometry imaging of multiple neuropeptides in the brain and alterations induced by experimental parkinsonism and L-DOPA therapy.
Hulme H, Fridjonsdottir E, Gunnarsdottir H, ..., Svenningsson P, Andrén PE
Neurobiol. Dis. 137 (-) 104738 [2020-04-00; online 2020-01-10]
PubMed DOI Crossref
Screening for autoantibody targets in post-vaccination narcolepsy using proteome arrays.
Lind A, Eriksson D, Akel O, ..., Elding Larsson H, Landegren N
Scand. J. Immunol. 91 (4) e12864 [2020-04-00; online 2020-02-13]
PubMed DOI Crossref
Publisher Correction: MEMOTE for standardized genome-scale metabolic model testing.
Lieven C, Beber ME, Olivier BG, ..., Zakhartsev M, Zhang C
Nat. Biotechnol. 38 (4) 504 [2020-04-00; online 2020-04-09]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Phosphorylation Time-Course Study of the Response during Adenovirus Type 2 Infection.
Valdés A, Zhao H, Pettersson U, Lind SB
Proteomics 20 (7) e1900327 [2020-04-00; online 2020-02-25]
PubMed DOI Crossref
Perivascular Neuropilin-1 expression is an independent marker of improved survival in renal cell carcinoma.
Morin E, Lindskog C, Johansson M, ..., Claesson-Welsh L, Sjöberg E
J. Pathol. 250 (4) 387-396 [2020-04-00; online 2020-01-29]
DOI Crossref
Optimisation of the droplet split design for high acoustic particle enrichment in droplet microfluidics
Fornell A, Liu Z, Tenje M
Microelectronic Engineering 226 (-) 111303 [2020-04-00; online 2020-04-00]
PubMed DOI Crossref
Neuroimaging premenstrual dysphoric disorder: A systematic and critical review.
Dubol M, Epperson CN, Lanzenberger R, Sundström-Poromaa I, Comasco E
Front Neuroendocrinol 57 (-) 100838 [2020-04-00; online 2020-04-05]
PubMed DOI Crossref
Molecular characterization of a large unselected cohort of metastatic colorectal cancers in relation to primary tumor location, rare metastatic sites and prognosis.
Nunes L, Aasebø K, Mathot L, ..., Sjöblom T, Glimelius B
Acta Oncol 59 (4) 417-426 [2020-04-00; online 2020-01-10]
DOI Crossref
Modeling of biocatalytic reactions: A workflow for model calibration, selection, and validation using Bayesian statistics
Eisenkolb I, Jensch A, Eisenkolb K, ..., Spiess A, Radde NE
AIChE Journal 66 (4) - [2020-04-00; online 2019-12-05]
DOI Crossref
Microwave-Accelerated N-Acylation of Sulfoximines with Aldehydes under Catalyst-Free Conditions
Rajbongshi KK, Ambala S, Govender T, ..., Arvidsson PI, Naicker T
Synthesis 52 (08) 1279-1286 [2020-04-00; online 2020-01-29]
PubMed DOI Crossref
Maternal exposure to arsenic and mercury and associated risk of adverse birth outcomes in small-scale gold mining communities in Northern Tanzania.
Nyanza EC, Dewey D, Manyama M, ..., Hatfield J, Bernier FP
Environ Int 137 (-) 105450 [2020-04-00; online 2020-01-31]
PubMed DOI Crossref
MTHFR, TYMS and SLCO1B1 polymorphisms and adverse liver effects of methotrexate in rheumatoid arthritis.
Sundbaum JK, Baecklund E, Eriksson N, ..., Kohnke H, Wadelius M
Pharmacogenomics 21 (5) 337-346 [2020-04-00; online 2020-02-06]
PubMed DOI Crossref
Longitudinal serum biomarker screening identifies malate dehydrogenase 2 as candidate prognostic biomarker for Duchenne muscular dystrophy.
Signorelli M, Ayoglu B, Johansson C, ..., Al-Khalili Szigyarto C, Spitali P
J Cachexia Sarcopenia Muscle 11 (2) 505-517 [2020-04-00; online 2019-12-27]
PubMed DOI Crossref
Long-term proton pump inhibitor usage and the association with pancreatic cancer in Sweden.
Brusselaers N, Sadr-Azodi O, Engstrand L
J. Gastroenterol. 55 (4) 453-461 [2020-04-00; online 2019-12-06]
PubMed DOI Crossref
Investigation of the demetallation of 10-aryl substituted synthetic chlorins under acidic conditions.
Arkhypchuk AI, Xiong R, Borbas KE
J Inorg Biochem 205 (-) 110979 [2020-04-00; online 2020-01-03]
Ruisheng Xiong SciLifeLab Fellow
PubMed DOI Crossref
Inference of natural selection from ancient DNA.
Dehasque M, Ávila-Arcos MC, Díez-Del-Molino D, ..., Dalén L, Foote AD
Evol Lett 4 (2) 94-108 [2020-04-00; online 2020-03-18]
PubMed DOI Crossref
Incontinentia pigmenti: Generation of an IKBKG deficient human iPSC line (KICRi002-A-1) on a 46,XY background using CRISPR/Cas9.
Fatima A, Schuster J, Akram T, ..., Hoeber J, Dahl N
Stem Cell Res 44 (-) 101739 [2020-04-00; online 2020-02-20]
PubMed DOI Crossref
IL-15 and CD155 expression regulate LAT expression in murine DNAM1+ NK cells, enhancing their effectors functions.
Luu TT, Wagner AK, Schmied L, ..., Höglund P, Kadri N
Eur. J. Immunol. 50 (4) 494-504 [2020-04-00; online 2020-02-20]
PubMed DOI Crossref
Heparanase Facilitates PMA-Induced Megakaryocytic Differentiation in K562 Cells via Interleukin 6/STAT3 Pathway.
Wan LM, Zhang SK, Li SB, ..., Tan YX, Gong F
Thromb. Haemost. 120 (4) 647-657 [2020-04-00; online 2020-04-14]
PubMed DOI Crossref
Generation of a human Neurochondrin deficient iPSC line KICRi002-A-3 using CRISPR/Cas9.
Fatima A, Schuster J, Akram T, ..., Hoeber J, Dahl N
Stem Cell Res 44 (-) 101758 [2020-04-00; online 2020-03-13]
PubMed DOI Crossref
Establishing Trypanosoma cruzi farnesyl pyrophosphate synthase as a viable target for biosensor driven fragment-based lead discovery.
Opassi G, Nordström H, Lundin A, ..., Klebe G, Danielson UH
Protein Sci. 29 (4) 991-1003 [2020-04-00; online 2020-02-07]
DOI Crossref
Enclave-based oblivious RAM using Intel’s SGX
Rachid MH, Riley R, Malluhi Q
Computers & Security 91 (-) 101711 [2020-04-00; online 2020-04-00]
DOI Crossref
Defective membrane insertion of mutant Na,K‐ATPase, a cause of fatal epilepsy
Howard R, Ygberg S, Andersson M, ..., Lindstrand A, Aperia A
The FASEB Journal 34 (S1) 1-1 [2020-04-00; online 2020-04-18]
PubMed DOI Crossref
De Novo Clustering of Long-Read Transcriptome Data Using a Greedy, Quality Value-Based Algorithm.
Sahlin K, Medvedev P
J. Comput. Biol. 27 (4) 472-484 [2020-04-00; online 2020-03-16]
Kristoffer Sahlin SciLifeLab Fellow
PubMed DOI Crossref
Cell Cycle Profiling Reveals Protein Oscillation, Phosphorylation, and Localization Dynamics.
Herr P, Boström J, Rullman E, ..., Maddalo G, Altun M
Mol. Cell Proteomics 19 (4) 608-623 [2020-04-00; online 2020-02-12]
PubMed DOI Crossref
Cancer cell stemness, responses to experimental genotoxic treatments, cytomegalovirus protein expression and DNA replication stress in pediatric medulloblastomas.
Bartek J, Merchut-Maya JM, Maya-Mendoza A, ..., Söderberg-Nauclér C, Bartkova J
Cell Cycle 19 (7) 727-741 [2020-04-00; online 2020-02-13]
PubMed DOI Crossref
CYP2C9, VKORC1, and CYP4F2 polymorphisms and pediatric warfarin maintenance dose: a systematic review and meta-analysis.
Takeuchi M, Kobayashi T, Biss T, ..., Brandão LR, Ito S
Pharmacogenomics J. 20 (2) 306-319 [2020-04-00; online 2019-11-01]
PubMed DOI Crossref
Application of unsupervised learning and process simulation for energy optimization of a WWTP under various weather conditions.
Borzooei S, Miranda GHB, Abolfathi S, ..., Meucci L, Zanetti MC
Water Sci Technol 81 (8) 1541-1551 [2020-04-00; online 2020-07-10]
Gisele Miranda SciLifeLab Fellow
PubMed DOI Crossref
An adipocyte-specific defect in oxidative phosphorylation increases systemic energy expenditure and protects against diet-induced obesity in mouse models.
Choi MJ, Jung SB, Lee SE, ..., Yi HS, Shong M
Diabetologia 63 (4) 837-852 [2020-04-00; online 2020-01-10]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Acute cocaine treatment enhances the antagonistic allosteric adenosine A2A-dopamine D2 receptor-receptor interactions in rat dorsal striatum without increasing significantly extracellular dopamine levels.
Romero-Fernandez W, Zhou Z, Beggiato S, ..., Ferraro L, Fuxe K
Pharmacol Rep 72 (2) 332-339 [2020-04-00; online 2020-03-02]
PubMed DOI Crossref
A Multi-Omics Approach to Liver Diseases: Integration of Single Nuclei Transcriptomics with Proteomics and HiCap Bulk Data in Human Liver.
Cavalli M, Diamanti K, Pan G, ..., Komorowski J, Wadelius C
OMICS 24 (4) 180-194 [2020-04-00; online 2020-03-16]
PubMed DOI Crossref
Transcriptome Profiling and Toxicity Following Long-Term, Low Dose Exposure of Human Lung Cells to Ni and NiO Nanoparticles-Comparison with NiCl2.
Gliga AR, Di Bucchianico S, Åkerlund E, Karlsson HL
Nanomaterials (Basel) 10 (4) - [2020-03-31; online 2020-03-31]
DOI Crossref
Rare variants in dynein heavy chain genes in two individuals with situs inversus and developmental dyslexia
Bieder A, Einarsdottir E, Matsson H, ..., Kere J, Tapia-Páez I
- - (-) - [2020-03-31; online 2020-03-31]
DOI Crossref
Peer Review Report For: Sarek: A portable workflow for whole-genome sequencing analysis of germline and somatic variants [version 1; peer review: 2 approved]
- - (-) - [2020-03-31; online 2020-03-31]
PubMed DOI Crossref
Author Correction: An optochemical tool for light-induced dissociation of adherens junctions to control mechanical coupling between cells.
Ollech D, Pflästerer T, Shellard A, ..., Wombacher R, Cavalcanti-Adam EA
Nat Commun 11 (1) 1681 [2020-03-31; online 2020-03-31]
PubMed DOI Crossref
Structural basis for the increased processivity of D-family DNA polymerases in complex with PCNA.
Madru C, Henneke G, Raia P, ..., Carroni M, Sauguet L
Nat Commun 11 (1) 1591 [2020-03-27; online 2020-03-27]
PubMed DOI Crossref
Deficits in Motor Performance, Neurotransmitters and Synaptic Plasticity in Elderly and Experimental Parkinsonian Mice Lacking GPR37.
Zhang X, Mantas I, Fridjonsdottir E, ..., Chergui K, Svenningsson P
Front Aging Neurosci 12 (-) 84 [2020-03-27; online 2020-03-27]
DOI Crossref
Revealing ecologically coherent population structure of uncultivated bacterioplankton with POGENOM
Sjöqvist C, Delgado Zambrano L, Alneberg J, Andersson A
- - (-) - [2020-03-26; online 2020-03-26]
PubMed DOI Crossref
Oxytocin Receptors Regulate Social Preference in Zebrafish.
Landin J, Hovey D, Xu B, ..., Kettunen P, Westberg L
Sci Rep 10 (1) 5435 [2020-03-25; online 2020-03-25]
PubMed DOI Crossref
Hippo-YAP1 Is a Prognosis Marker and Potentially Targetable Pathway in Advanced Gallbladder Cancer.
García P, Rosa L, Vargas S, ..., Roa JC, Bizama C
Cancers (Basel) 12 (4) - [2020-03-25; online 2020-03-25]
DOI Crossref
Genomic basis of parallel adaptation varies with divergence in Arabidopsis and its relatives
Bohutínská M, Vlček J, Yair S, ..., Slotte T, Kolář F
bioRxiv - (-) - [2020-03-25; online 2020-03-25]
SciLifeLab Fellow Tanja Slotte
DOI Crossref
Author response: Vascular permeability in retinopathy is regulated by VEGFR2 Y949 signaling to VE-cadherin
Smith RO, Ninchoji T, Gordon E, ..., Kvanta A, Claesson-Welsh L
- - (-) - [2020-03-24; online 2020-03-24]
PubMed DOI Crossref
An atlas of human metabolism.
Robinson JL, Kocabaş P, Wang H, ..., Uhlén M, Nielsen J
Sci Signal 13 (624) eaaz1482 [2020-03-24; online 2020-03-24]
Adil Mardinoglu Avlant Nilsson DDLS Fellow SciLifeLab Fellow
PubMed DOI Crossref
TGF-β Signaling.
Tzavlaki K, Moustakas A
Biomolecules 10 (3) - [2020-03-23; online 2020-03-23]
PubMed DOI Crossref
Marine Sediments Illuminate Chlamydiae Diversity and Evolution.
Dharamshi JE, Tamarit D, Eme L, ..., Spang A, Ettema TJG
Curr. Biol. 30 (6) 1032-1048.e7 [2020-03-23; online 2020-03-05]
PubMed DOI Crossref
Molecular Profiling for Predictors of Radiosensitivity in Patients with Breast or Head-and-Neck Cancer.
Drobin K, Marczyk M, Halle M, ..., Schwenk JM, Haghdoost S
Cancers (Basel) 12 (3) - [2020-03-22; online 2020-03-22]
DOI Crossref
Streamlined freshwater bacterioplankton Nanopelagicales (acI) and “ Ca . Fonsibacter” (LD12) thrive in functional cohorts
Mondav R, Bertilsson S, Buck M, ..., Lindström ES, Garcia SL
- - (-) - [2020-03-20; online 2020-03-20]
Sarahi Garcia SciLifeLab Fellow
PubMed DOI Crossref
Non-dopaminergic Alterations in Depression-Like FSL Rats in Experimental Parkinsonism and L-DOPA Responses.
Schintu N, Zhang X, Stroth N, ..., Andrén PE, Svenningsson P
Front. Pharmacol. 11 (-) 304 [2020-03-20; online 2020-03-20]
PubMed DOI Crossref
Electrochemical Biosensors Based on S-Layer Proteins.
Damiati S, Schuster B
Sensors (Basel) 20 (6) - [2020-03-19; online 2020-03-19]
PubMed DOI Crossref
Cathepsin K regulates localization and secretion of Tartrate-Resistant Acid Phosphatase (TRAP) in TRAP-overexpressing MDA-MB-231 breast cancer cells.
Reithmeier A, Norgård M, Ek-Rylander B, Näreoja T, Andersson G
BMC Mol Cell Biol 21 (1) 15 [2020-03-18; online 2020-03-18]
PubMed DOI Crossref
Newborn Screening for Presymptomatic Diagnosis of Complement and Phagocyte Deficiencies.
Dezfouli M, Bergström S, Skattum L, ..., Nilsson P, Hammarström L
Front Immunol 11 (-) 455 [2020-03-17; online 2020-03-17]
DOI Crossref
Multi-HLA class II tetramer analyses of citrulline-reactive T cells and early treatment response in rheumatoid arthritis
Gerstner C, Turcinov S, Hensvold AH, ..., Baarsen LGMv, Malmström V
- - (-) - [2020-03-17; online 2020-03-17]
PubMed DOI Crossref
Monoamine oxidase A genotype and methylation moderate the association of maltreatment and aggressive behaviour.
Checknita D, Bendre M, Ekström TJ, ..., Hodgins S, Nilsson KW
Behav. Brain Res. 382 (-) 112476 [2020-03-16; online 2020-01-10]
Erika Comasco SciLifeLab Fellow
DOI Crossref
Facets of individual-specific health signatures determined from longitudinal plasma proteome profiling
Dodig-Crnković T, Hong MG, Thomas CE, ..., Uhlén M, Schwenk JM
bioRxiv - (-) - [2020-03-15; online 2020-03-15]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
Ecosystem-wide metagenomic binning enables prediction of ecological niches from genomes.
Alneberg J, Bennke C, Beier S, ..., Pinhassi J, Andersson AF
Commun Biol 3 (1) 119 [2020-03-13; online 2020-03-13]
PubMed DOI Crossref
Benefit of Later-Time-Point PET Imaging of HER3 Expression Using Optimized Radiocobalt-Labeled Affibody Molecules.
Rinne SS, Dahlsson Leitao C, Saleh-Nihad Z, ..., Löfblom J, Orlova A
Int J Mol Sci 21 (6) - [2020-03-13; online 2020-03-13]
PubMed DOI Crossref
A heat-sensitive Osh protein controls PI4P polarity.
Omnus DJ, Cadou A, Thomas FB, ..., Vaughan AN, Stefan CJ
BMC Biol. 18 (1) 28 [2020-03-13; online 2020-03-13]
PubMed DOI Crossref
Introducing Hann windows for reducing edge-effects in patch-based image segmentation.
Pielawski N, Wählby C
PLoS ONE 15 (3) e0229839 [2020-03-12; online 2020-03-12]
PubMed DOI Crossref
Interaction With 14-3-3 Correlates With Inactivation of the RIG-I Signalosome by Herpesvirus Ubiquitin Deconjugases.
Gupta S, Ylä-Anttila P, Sandalova T, Achour A, Masucci MG
Front Immunol 11 (-) 437 [2020-03-12; online 2020-03-12]
PubMed DOI Crossref
High-parametric evaluation of human invariant natural killer T cells to delineate heterogeneity in allo- and autoimmunity.
Erkers T, Xie BJ, Kenyon LJ, ..., Maecker HT, Meyer EH
Blood 135 (11) 814-825 [2020-03-12; online 2020-01-15]
PubMed DOI Crossref
ATR expands embryonic stem cell fate potential in response to replication stress.
Atashpaz S, Samadi Shams S, Gonzalez JM, ..., López-Contreras AJ, Costanzo V
Elife 9 (-) - [2020-03-12; online 2020-03-12]
PubMed DOI Crossref
Exploiting loss of heterozygosity for allele-selective colorectal cancer chemotherapy.
Rendo V, Stoimenov I, Mateus A, ..., Cheong I, Sjöblom T
Nat Commun 11 (1) 1308 [2020-03-11; online 2020-03-11]
PubMed DOI Crossref
Affibody Molecules as Targeting Vectors for PET Imaging.
Tolmachev V, Orlova A
Cancers (Basel) 12 (3) - [2020-03-11; online 2020-03-11]
PubMed DOI Crossref
Short and simple sequences favored the emergence of N-helix phospho-ligand binding sites in the first enzymes.
Longo LM, Petrović D, Kamerlin SCL, Tawfik DS
Proc. Natl. Acad. Sci. U.S.A. 117 (10) 5310-5318 [2020-03-10; online 2020-02-20]
PubMed DOI Crossref
Identification of germline variants in adults with hemophagocytic lymphohistiocytosis.
Miller PG, Niroula A, Ceremsak JJ, ..., Berliner N, Ebert BL
Blood Adv 4 (5) 925-929 [2020-03-10; online 2020-03-10]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy.
Georganaki M, Ramachandran M, Tuit S, ..., Tugues S, Dimberg A
Oncoimmunology 9 (1) 1730538 [2020-03-09; online 2020-03-09]
DOI Crossref
Towards a Computational Ecotoxicity Assay
Kamerlin N, Delcey MG, Manzetti S, van der Spoel D
- - (-) - [2020-03-06; online 2020-03-06]
PubMed DOI Crossref
Ribonucleotide reductase inhibitors suppress SAMHD1 ara-CTPase activity enhancing cytarabine efficacy.
Rudd SG, Tsesmetzis N, Sanjiv K, ..., Helleday T, Herold N
EMBO Mol Med 12 (3) e10419 [2020-03-06; online 2020-01-17]
PubMed DOI Crossref
Cathepsin g Degrades Both Glycosylated and Unglycosylated Regions of Lubricin, a Synovial Mucin.
Huang S, Thomsson KA, Jin C, ..., Karlsson NG, Eisler T
Sci Rep 10 (1) 4215 [2020-03-06; online 2020-03-06]
PubMed DOI Crossref
An atlas of the protein-coding genes in the human, pig, and mouse brain.
Sjöstedt E, Zhong W, Fagerberg L, ..., Uhlén M, Mulder J
Science (New York, N.Y.) 367 (6482) eaay5947 [2020-03-06; online 2020-03-07]
Adil Mardinoglu DDLS Fellow Fredrik Edfors SciLifeLab Fellow
DOI Crossref
Undinarchaeota illuminate the evolution of DPANN archaea
Dombrowski N, Williams TA, Sun J, ..., Rinke C, Spang A
- - (-) - [2020-03-05; online 2020-03-05]
PubMed DOI Crossref
Stressful Beginnings with Long-Term Consequences.
Consiglio CR, Brodin P
Cell 180 (5) 820-821 [2020-03-05; online 2020-03-07]
Camila Consiglio DDLS Fellow
PubMed DOI Crossref
Membrane lipids are both the substrates and a mechanistically responsive environment of TMEM16 scramblase proteins.
Khelashvili G, Cheng X, Falzone ME, ..., Accardi A, Weinstein H
J Comput Chem 41 (6) 538-551 [2020-03-05; online 2019-11-21]
DDLS Fellow Milka Doktorova
DOI Crossref
Marine snow as a habitat for microbial mercury methylators in the Baltic Sea
Capo E, Bravo AG, Soerensen AL, ..., Buck M, Björn E
- - (-) - [2020-03-05; online 2020-03-05]
DOI Crossref
Leaky severe combined immunodeficiency in mice lacking non-homologous end joining factors XLF and MRI
Castañeda-Zegarra S, Zhang Q, Alirezaylavasani A, ..., Yao R, Oksenych V
- - (-) - [2020-03-05; online 2020-03-05]
PubMed DOI Crossref
Epiphyseal Cartilage Formation Involves Differential Dynamics of Various Cellular Populations During Embryogenesis.
Zhang Y, Annusver K, Sunadome K, ..., Adameyko I, Xie M
Front Cell Dev Biol 8 (-) 122 [2020-03-05; online 2020-03-05]
PubMed DOI Crossref
(Radio)Theranostic Patient Management in Oncology Exemplified by Neuroendocrine Neoplasms, Prostate Cancer, and Breast Cancer.
Velikyan I
Pharmaceuticals (Basel, Switzerland) 13 (3) - [2020-03-05; online 2020-03-05]
DOI Crossref
Nonpharmacological treatment options for Alzheimer’s disease: from animal testing to clinical studies
TÜRKEZ H, ARSLAN ME, STEFANO AD, CACCIATORE I, MARDİNOĞLU A
Turk J Zool 44 (2) 81-89 [2020-03-04; online 2020-03-04]
PubMed DOI Crossref
OPENchip: an on-chip in situ molecular profiling platform for gene expression analysis and oncogenic mutation detection in single circulating tumour cells.
Lee AC, Svedlund J, Darai E, ..., Nilsson M, Kwon S
Lab Chip 20 (5) 912-922 [2020-03-03; online 2020-02-15]
PubMed DOI Crossref
Macrocyclic Peptides Uncover a Novel Binding Mode for Reversible Inhibitors of LSD1.
Yang J, Talibov VO, Peintner S, ..., Danielson UH, Kihlberg J
ACS Omega 5 (8) 3979-3995 [2020-03-03; online 2020-02-17]
PubMed DOI Crossref
How the matrix metalloproteinase MMP14 contributes to the progression of colorectal cancer.
Claesson-Welsh L
J. Clin. Invest. 130 (3) 1093-1095 [2020-03-02; online 2020-02-06]
PubMed DOI Crossref
Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age.
Merid SK, Novoloaca A, Sharp GC, ..., London SJ, Melén E
Genome Med 12 (1) 25 [2020-03-02; online 2020-03-02]
PubMed DOI Crossref
Acid-Cleavable Poly(ethylene glycol) Hydrogels Displaying Protein Release at pH 5.
Ewald J, Blankenburg J, Worm M, ..., Frey H, Pohlit H
Chemistry 26 (13) 2947-2953 [2020-03-02; online 2020-02-18]
PubMed DOI Crossref
The sweet detection of rolling circle amplification: Glucose-based electrochemical genosensor for the detection of viral nucleic acid.
Ciftci S, Cánovas R, Neumann F, ..., Crespo GA, Madaboosi N
Biosens Bioelectron 151 (-) 112002 [2020-03-01; online 2019-12-30]
PubMed DOI Crossref
SynQuant: an automatic tool to quantify synapses from microscopy images.
Wang Y, Wang C, Ranefall P, ..., Tian L, Yu G
Bioinformatics 36 (5) 1599-1606 [2020-03-01; online 2019-10-10]
PubMed DOI Crossref
PhyloMagnet: fast and accurate screening of short-read meta-omics data using gene-centric phylogenetics.
Schön ME, Eme L, Ettema TJG
Bioinformatics 36 (6) 1718-1724 [2020-03-01; online 2019-10-28]
PubMed DOI Crossref
*-DCC: A platform to collect, annotate, and explore a large variety of sequencing experiments.
Hörtenhuber M, Mukarram AK, Stoiber MH, Brown JB, Daub CO
Gigascience 9 (3) - [2020-03-01; online 2020-03-15]
PubMed DOI Crossref
White matter microstructure mediates the association between prenatal exposure to phthalates and behavior problems in preschool children.
England-Mason G, Grohs MN, Reynolds JE, ..., Dewey D, APrON Study Team
Environ. Res. 182 (-) 109093 [2020-03-00; online 2019-12-26]
PubMed DOI Crossref
Tumor localized agonistic anti-CD40 therapy and beyond.
Eltahir M, Persson H, Mangsbo S
Expert Opin Biol Ther 20 (3) 215-217 [2020-03-00; online 2020-01-10]
PubMed DOI Crossref
Thoracolumbar meningeal fibrosis in pugs.
Rohdin C, Ljungvall I, Häggström J, ..., Wohlsein P, Jäderlund KH
J. Vet. Intern. Med. 34 (2) 797-807 [2020-03-00; online 2020-01-31]
PubMed DOI Crossref
The nf-core framework for community-curated bioinformatics pipelines.
Ewels PA, Peltzer A, Fillinger S, ..., Di Tommaso P, Nahnsen S
Nat. Biotechnol. 38 (3) 276-278 [2020-03-00; online 2020-02-15]
PubMed DOI Crossref
The landscape of viral associations in human cancers.
Zapatka M, Borozan I, Brewer DS, ..., Lichter P, PCAWG Consortium
Nat. Genet. 52 (3) 320-330 [2020-03-00; online 2020-02-05]
PubMed DOI Crossref
The Apoptosis Pathway and CASP8 Variants Conferring Risk for Acute and Overuse Musculoskeletal Injuries.
Seale K, Burger M, Posthumus M, ..., Collins M, September AV
J Orthop Res 38 (3) 680-688 [2020-03-00; online 2019-11-11]
PubMed DOI Crossref
TH1579, MTH1 inhibitor, delays tumour growth and inhibits metastases development in osteosarcoma model.
Moukengue B, Brown HK, Charrier C, ..., Ory B, Lamoureux F
EBioMedicine 53 (-) 102704 [2020-03-00; online 2020-03-07]
PubMed DOI Crossref
Synthesis, Evaluation and Proposed Binding Pose of Substituted Spiro-Oxindole Dihydroquinazolinones as IRAP Inhibitors.
Engen K, Vanga SR, Lundbäck T, ..., Larhed M, Rosenström U
ChemistryOpen 9 (3) 325-337 [2020-03-00; online 2020-03-02]
PubMed DOI Crossref
Structure of a minimal photosystem I from the green alga Dunaliella salina.
Perez-Boerema A, Klaiman D, Caspy I, ..., Amunts A, Nelson N
Nat Plants 6 (3) 321-327 [2020-03-00; online 2020-03-02]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Performance of virtual screening against GPCR homology models: Impact of template selection and treatment of binding site plasticity.
Jaiteh M, Rodríguez-Espigares I, Selent J, Carlsson J
PLoS Comput Biol 16 (3) e1007680 [2020-03-00; online 2020-03-13]
Jens Carlsson SciLifeLab Fellow
DOI Crossref
P96 The regulation and pharmacological modulation of immune complex induced production of type III IFN by plasmacytoid dendritic cells
Hjorton K, Hagberg N, Pucholt P, ..., Eloranta ML, Rönnblom L
- - (-) A74.3-A75 [2020-03-00; online 2020-03-23]
DOI Crossref
P190 A simplified approach for patients with SLE to report disease activity using a revised version of the swedish systemic lupus activity questionnaire
Pettersson S, Illescas-Bäckelin V, Jönsen A, ..., Sjöwall C, Svenungsson E
- - (-) A122.2-A123 [2020-03-00; online 2020-03-23]
PubMed DOI Crossref
Overexpression of chromatin remodeling and tyrosine kinase genes in iAMP21-positive acute lymphoblastic leukemia.
Ivanov Öfverholm I, Zachariadis V, Taylan F, ..., Nordlund J, Barbany G
Leuk. Lymphoma 61 (3) 604-613 [2020-03-00; online 2019-10-22]
PubMed DOI Crossref
No evidence for DNA N 6-methyladenine in mammals.
Douvlataniotis K, Bensberg M, Lentini A, Gylemo B, Nestor CE
Sci Adv 6 (12) eaay3335 [2020-03-00; online 2020-03-18]
Antonio Lentini DDLS Fellow
PubMed DOI Crossref
Microbiome and Gastric Cancer.
Engstrand L, Graham DY
Dig Dis Sci 65 (3) 865-873 [2020-03-00; online 2020-02-11]
PubMed DOI Crossref
MEMOTE for standardized genome-scale metabolic model testing.
Lieven C, Beber ME, Olivier BG, ..., Zakhartsev M, Zhang C
Nat. Biotechnol. 38 (3) 272-276 [2020-03-00; online 2020-03-04]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Longitudinal changes in the frequency of mosaic chromosome Y loss in peripheral blood cells of aging men varies profoundly between individuals.
Danielsson M, Halvardson J, Davies H, ..., Dumanski JP, Forsberg LA
Eur. J. Hum. Genet. 28 (3) 349-357 [2020-03-00; online 2019-10-25]
PubMed DOI Crossref
Long-read metabarcoding of the eukaryotic rDNA operon to phylogenetically and taxonomically resolve environmental diversity.
Jamy M, Foster R, Barbera P, ..., Bass D, Burki F
Mol Ecol Resour 20 (2) 429-443 [2020-03-00; online 2019-11-29]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Life in the dark: far-red absorbing cyanobacteria extend photic zones deep into terrestrial caves.
Behrendt L, Trampe EL, Nord NB, ..., Hershey OS, Barton H
Environ. Microbiol. 22 (3) 952-963 [2020-03-00; online 2019-09-09]
Lars Behrendt SciLifeLab Fellow
PubMed DOI Crossref
Irreversible TrxR1 inhibitors block STAT3 activity and induce cancer cell death.
Busker S, Qian W, Haraldsson M, ..., Tamm KP, Page BDG
Sci Adv 6 (12) eaax7945 [2020-03-00; online 2020-03-20]
DOI Crossref
In Situ Encapsulation of Nile Red or Doxorubicin during RAFT‐Mediated Emulsion Polymerization via Polymerization‐Induced Self‐Assembly for Biomedical Applications
Engström J, Asem H, Brismar H, ..., Malkoch M, Malmström E
Macro Chemistry & Physics 221 (5) - [2020-03-00; online 2020-02-10]
PubMed DOI Crossref
High genetic risk score is associated with early disease onset, damage accrual and decreased survival in systemic lupus erythematosus.
Reid S, Alexsson A, Frodlund M, ..., Rönnblom L, Leonard D
Ann. Rheum. Dis. 79 (3) 363-369 [2020-03-00; online 2019-12-11]
PubMed DOI Crossref
Global variability analysis of mRNA and protein concentrations across and within human tissues.
Wegler C, Ölander M, Wiśniewski JR, ..., Andersson TB, Artursson P
NAR Genomics and Bioinformatics 2 (1) lqz010 [2020-03-00; online 2019-10-30]
PubMed DOI Crossref
Evolution of P2A and P5A ATPases: ancient gene duplications and the red algal connection to green plants revisited.
Palmgren M, Sørensen DM, Hallström BM, Säll T, Broberg K
Physiol Plant 168 (3) 630-647 [2020-03-00; online 2019-08-08]
PubMed DOI Crossref
Early increment of soluble triggering receptor expressed on myeloid cells 2 in plasma might be a predictor of poor outcome after ischemic stroke.
Kwon HS, Lee EH, Park HH, ..., Kamali-Moghaddam M, Koh SH
J Clin Neurosci 73 (-) 215-218 [2020-03-00; online 2020-02-14]
PubMed DOI Crossref
Distinct structural modulation of photosystem I and lipid environment stabilizes its tetrameric assembly.
Chen M, Perez-Boerema A, Zhang L, ..., Li S, Amunts A
Nat Plants 6 (3) 314-320 [2020-03-00; online 2020-03-09]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing.
Cortés-Ciriano I, Lee JJ, Xi R, ..., Park PJ, PCAWG Consortium
Nat. Genet. 52 (3) 331-341 [2020-03-00; online 2020-02-05]
PubMed DOI Crossref
Chemical imaging of evolving amyloid plaque pathology and associated Aβ peptide aggregation in a transgenic mouse model of Alzheimer's disease.
Michno W, Wehrli P, Meier SR, ..., Blennow K, Hanrieder J
J. Neurochem. 152 (5) 602-616 [2020-03-00; online 2019-11-06]
SciLifeLab Fellow Wojciech Michno
PubMed DOI Crossref
Butler enables rapid cloud-based analysis of thousands of human genomes.
Yakneen S, Waszak SM, PCAWG Technical Working Group , ..., Korbel JO, PCAWG Consortium
Nat. Biotechnol. 38 (3) 288-292 [2020-03-00; online 2020-02-05]
PubMed DOI Crossref
Autophagy role(s) in response to oncogenes and DNA replication stress.
Vanzo R, Bartkova J, Merchut-Maya JM, ..., Jäättelä M, Bartek J
Cell Death Differ. 27 (3) 1134-1153 [2020-03-00; online 2019-08-14]
PubMed DOI Crossref
A putative silencer variant in a spontaneous canine model of retinitis pigmentosa.
Kaukonen M, Quintero IB, Mukarram AK, ..., Lohi H, DoGA Consortium
PLoS Genet 16 (3) e1008659 [2020-03-00; online 2020-03-09]
DOI Crossref
Super-resolved spatial transcriptomics by deep data fusion
Bergenstråhle L, He B, Bergenstråhle J, ..., Zou J, Maaskola J
- - (-) - [2020-02-28; online 2020-02-28]
PubMed DOI Crossref
PCSK6 Is a Key Protease in the Control of Smooth Muscle Cell Function in Vascular Remodeling.
Rykaczewska U, Suur BE, Röhl S, ..., Hedin U, Matic L
Circ. Res. 126 (5) 571-585 [2020-02-28; online 2020-01-02]
PubMed DOI Crossref
Impact of Nanoscale Hindrances on the Relationship between Lipid Packing and Diffusion in Model Membranes.
Beckers D, Urbancic D, Sezgin E
J Phys Chem B 124 (8) 1487-1494 [2020-02-27; online 2020-02-18]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Complete Range of the Universal mtDNA Gene Pool and High Genetic Diversity in the Thai Dog Population.
Zhang L, Liu Y, Thai Ke Q, ..., Boonyaprakob U, Savolainen P
Genes (Basel) 11 (3) - [2020-02-27; online 2020-02-27]
PubMed DOI Crossref
A comprehensive analysis of coding and non-coding transcriptomic changes in cutaneous squamous cell carcinoma.
Das Mahapatra K, Pasquali L, Søndergaard JN, ..., Kristensen LS, Pivarcsi A
Sci Rep 10 (1) 3637 [2020-02-27; online 2020-02-27]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Streptococcus pneumoniae Nasopharyngeal Carriage among PCV-10-Vaccinated HIV-1-Infected Children with Maintained Serological Memory in Ethiopia.
Lemma M, Bekele Y, Petkov S, ..., Howe R, Chiodi F
Pathogens 9 (3) - [2020-02-25; online 2020-02-25]
PubMed DOI Crossref
Proposal of a Taxonomic Nomenclature for the Bacillus cereus Group Which Reconciles Genomic Definitions of Bacterial Species with Clinical and Industrial Phenotypes.
Carroll LM, Wiedmann M, Kovac J
MBio 11 (1) - [2020-02-25; online 2020-02-25]
DDLS Fellow Laura Carroll
PubMed DOI Crossref
Phenotypic Variability with SLURP1 Mutations and Diffuse Palmoplantar Keratoderma.
Harjama L, Kettunen K, Elomaa O, ..., Hadj-Rabia S, Hannula-Jouppi K
Acta Derm Venereol 100 (4) adv00060 [2020-02-25; online 2020-02-25]
PubMed DOI Crossref
Improved Synthesis and Isolation of Bedaquiline.
Lubanyana H, Arvidsson PI, Govender T, Kruger HG, Naicker T
ACS Omega 5 (7) 3607-3611 [2020-02-25; online 2020-02-17]
PubMed DOI Crossref
Energy Landscapes Reveal Agonist Control of G Protein-Coupled Receptor Activation via Microswitches.
Fleetwood O, Matricon P, Carlsson J, Delemotte L
Biochemistry 59 (7) 880-891 [2020-02-25; online 2020-02-07]
Jens Carlsson Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Correction: Glioblastoma and glioblastoma stem cells are dependent on functional MTH1.
Pudelko L, Rouhi P, Sanjiv K, ..., Helleday T, Bräutigam L
Oncotarget 11 (8) 827 [2020-02-25; online 2020-02-25]
DOI Crossref
Rapid colorimetric detection of COVID-19 coronavirus using a reverse transcriptional loop-mediated isothermal amplification (RT-LAMP) diagnostic platform: iLACO
Yu L, Wu S, Hao X, ..., Chen WH, Yin X
- - (-) - [2020-02-24; online 2020-02-24]
SciLifeLab Fellow
PubMed DOI Crossref
Patterns of African and Asian admixture in the Afrikaner population of South Africa.
Hollfelder N, Erasmus JC, Hammaren R, ..., Greeff JM, Schlebusch CM
BMC Biol. 18 (1) 16 [2020-02-24; online 2020-02-24]
PubMed DOI Crossref
rs953413 Regulates Polyunsaturated Fatty Acid Metabolism by Modulating ELOVL2 Expression.
Pan G, Cavalli M, Carlsson B, ..., Kumar C, Wadelius C
iScience 23 (2) 100808 [2020-02-21; online 2020-01-09]
DOI Crossref
Achieving symptom relief in patients with Myalgic encephalomyelitis by targeting the neuro-immune interface and inducing disease tolerance
Rodriguez LST, Pou C, Lakshmikanth T, ..., Julin P, Brodin P
- - (-) - [2020-02-21; online 2020-02-21]
PubMed DOI Crossref
A Guide to Carrying Out a Phylogenomic Target Sequence Capture Project.
Andermann T, Torres Jiménez MF, Matos-Maraví P, ..., Bacon CD, Antonelli A
Front Genet 10 (-) 1407 [2020-02-21; online 2020-02-21]
DDLS Fellow Tobias Andermann
PubMed DOI Crossref
In silico and In vitro Investigation of a Likely Pathway for Anti-Cancerous Effect of Thrombocidin-1 as a Novel Anticancer Peptide.
Tanhaian A, Mohammadi E, Vakili-Ghartavol R, ..., Mirzayi M, Jaafari MR
Protein Pept Lett 27 (8) 751-762 [2020-02-20; online 2020-02-20]
PubMed DOI Crossref
Towards a European health research and innovation cloud (HRIC).
Aarestrup FM, Albeyatti A, Armitage WJ, ..., Van den Bulcke M, Van Oyen H
Genome Med 12 (1) 18 [2020-02-19; online 2020-02-19]
PubMed DOI Crossref
Primary cell wall inspired micro containers as a step towards a synthetic plant cell.
Paulraj T, Wennmalm S, Wieland DCF, ..., Cárdenas M, Svagan AJ
Nat Commun 11 (1) 958 [2020-02-19; online 2020-02-19]
PubMed DOI Crossref
Enhanced sampling and free energy calculations for protein simulations.
Liao Q
Prog Mol Biol Transl Sci 170 (-) 177-213 [2020-02-19; online 2020-02-19]
DOI Crossref
A whole-genome sequenced control population in northern Sweden reveals subregional genetic differences
Svensson D, Rentoft M, Dahlin AM, ..., Trygg J, Johansson E
- - (-) - [2020-02-19; online 2020-02-19]
PubMed DOI Crossref
Targeting the NPL4 Adaptor of p97/VCP Segregase by Disulfiram as an Emerging Cancer Vulnerability Evokes Replication Stress and DNA Damage while Silencing the ATR Pathway.
Majera D, Skrott Z, Chroma K, ..., Mistrik M, Bartek J
Cells 9 (2) - [2020-02-18; online 2020-02-18]
PubMed DOI Crossref
Creating Supported Plasma Membrane Bilayers Using Acoustic Pressure.
Sezgin E, Carugo D, Levental I, Stride E, Eggeling C
Membranes (Basel) 10 (2) 30 [2020-02-18; online 2020-02-18]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Biophysical Characterization of Epigallocatechin-3-Gallate Effect on the Cardiac Sodium Channel Nav1.5.
Amarouch MY, Kurt H, Delemotte L, Abriel H
Molecules 25 (4) 902 [2020-02-18; online 2020-02-18]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
G Protein-Gated Inwardly Rectifying Potassium Channel Subunit 3 is Upregulated in Rat DRGs and Spinal Cord After Peripheral Nerve Injury.
Lyu C, Lyu GW, Mulder J, Martinez A, Shi TS
J Pain Res 13 (-) 419-429 [2020-02-17; online 2020-02-17]
PubMed DOI Crossref
Influence of Residualizing Properties of the Radiolabel on Radionuclide Molecular Imaging of HER3 Using Affibody Molecules.
Rinne SS, Xu T, Dahlsson Leitao C, ..., Tolmachev V, Vorobyeva A
Int J Mol Sci 21 (4) - [2020-02-15; online 2020-02-15]
PubMed DOI Crossref
GLI1-induced mammary gland tumours are transplantable and maintain major molecular features.
Norum JH, Frings O, Kasper M, ..., Sørlie T, Toftgård R
Int. J. Cancer 146 (4) 1125-1138 [2020-02-15; online 2019-07-08]
PubMed DOI Crossref
Effect of a radiolabel biochemical nature on tumor-targeting properties of EpCAM-binding engineered scaffold protein DARPin Ec1.
Deyev SM, Vorobyeva A, Schulga A, ..., Orlova A, Tolmachev V
Int J Biol Macromol 145 (-) 216-225 [2020-02-15; online 2019-12-19]
PubMed DOI Crossref
The First Structure of an Active Mammalian dCTPase and its Complexes With Substrate Analogs and Products.
Scaletti E, Claesson M, Helleday T, Jemth AS, Stenmark P
J. Mol. Biol. 432 (4) 1126-1142 [2020-02-14; online 2020-01-15]
DOI Crossref
Live cell imaging reveals that RecA finds homologous DNA by reduced dimensionality search
Wiktor J, Gynnå AH, Leroy P, ..., Testa I, Elf J
- - (-) - [2020-02-14; online 2020-02-14]
Ilaria Testa SciLifeLab Fellow
DOI Crossref
Conservation Genomic Analyses of African and Asiatic Cheetahs ( Acinonyx jubatus) Across Their Current and Historical Species Range
Prost S, Machado AP, Zumbroich J, ..., Kotze A, Burger PA
- - (-) - [2020-02-14; online 2020-02-14]
DOI Crossref
The irradiated brain microenvironment supports glioma stemness and survival via astrocyte-derived Transglutaminase 2
Berg TJ, Marques C, Pantazopoulou V, ..., Squatrito M, Pietras A
- - (-) - [2020-02-13; online 2020-02-13]
DOI Crossref
Spage2vec: Unsupervised detection of spatial gene expression constellations
Partel G, Wählby C
- - (-) - [2020-02-13; online 2020-02-13]
PubMed DOI Crossref
Refined detection and phasing of structural aberrations in pediatric acute lymphoblastic leukemia by linked-read whole-genome sequencing.
Nordlund J, Marincevic-Zuniga Y, Cavelier L, ..., Lönnerholm G, Syvänen AC
Sci Rep 10 (1) 2512 [2020-02-13; online 2020-02-13]
PubMed DOI Crossref
Radial Organization in the Mammalian Nucleus.
Crosetto N, Bienko M
Front Genet 11 (-) 33 [2020-02-12; online 2020-02-12]
Magda Bienko SciLifeLab Fellow
DOI Crossref
Paladin is a PI(4,5)P 2 phosphoinositide phosphatase that regulates endosomal signaling and angiogenesis
Nitzsche A, Pietilä R, Testini C, ..., Claesson-Welsh L, Hellström M
- - (-) - [2020-02-12; online 2020-02-12]
PubMed DOI Crossref
Deriving disease modules from the compressed transcriptional space embedded in a deep autoencoder.
Dwivedi SK, Tjärnberg A, Tegnér J, Gustafsson M
Nat Commun 11 (1) 856 [2020-02-12; online 2020-02-12]
DOI Crossref
Predicting and elucidating the etiology of fatty liver disease using a machine learning-based approach: an IMI DIRECT study
Atabaki-Pasdar N, Ohlsson M, Viñuela A, ..., Pavo I, Franks PW
- - (-) - [2020-02-11; online 2020-02-11]
PubMed DOI Crossref
Lipidomic profiles, lipid trajectories and clinical biomarkers in female elite endurance athletes.
Varga TV, Ali A, Herrera JAR, ..., Brunak S, Tornberg ÅB
Sci Rep 10 (1) 2349 [2020-02-11; online 2020-02-11]
PubMed DOI Crossref
CDX2: A Prognostic Marker in Metastatic Colorectal Cancer Defining a Better BRAF Mutated and a Worse KRAS Mutated Subgroup.
Aasebø K, Dragomir A, Sundström M, ..., Glimelius B, Sorbye H
Front Oncol 10 (-) 8 [2020-02-11; online 2020-02-11]
PubMed DOI Crossref
Whole genome sequencing unveils genetic heterogeneity in optic nerve hypoplasia.
Dahl S, Pettersson M, Eisfeldt J, ..., Anderlid BM, Lindstrand A
PLoS ONE 15 (2) e0228622 [2020-02-10; online 2020-02-10]
DOI Crossref
Amplification-free long read sequencing reveals unforeseen CRISPR-Cas9 off-target activity
Höijer I, Johansson J, Gudmundsson S, ..., Gyllensten U, Ameur A
- - (-) - [2020-02-09; online 2020-02-09]
PubMed DOI Crossref
Transcriptomic profiling of experimental arterial injury reveals new mechanisms and temporal dynamics in vascular healing response.
Röhl S, Rykaczewska U, Seime T, ..., Razuvaev A, Matic LP
JVS Vasc Sci 1 (-) 13-27 [2020-02-07; online 2020-02-07]
DOI Crossref
The proliferative history shapes the DNA methylome of B-cell tumors and predicts clinical outcome
Duran-Ferrer M, Clot G, Nadeu F, ..., Campo E, Martin-Subero JI
- - (-) - [2020-02-07; online 2020-02-07]
DOI Crossref
SCRINSHOT, a spatial method for single-cell resolution mapping of cell states in tissue sections
Sountoulidis A, Liontos A, Nguyen HP, ..., Nilsson M, Samakovlis C
- - (-) - [2020-02-07; online 2020-02-07]
DOI Crossref
Predatory colponemids are the sister group to all other alveolates
Tikhonenkov DV, Strassert JFH, Janouškovec J, ..., Burki F, Keeling PJ
bioRxiv - (-) - [2020-02-07; online 2020-02-07]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Frequency dependent multiphase flows on centrifugal microfluidics.
Pishbin E, Kazemzadeh A, Chimerad M, ..., Navidbakhsh M, Russom A
Lab Chip 20 (3) 514-524 [2020-02-07; online 2020-01-03]
PubMed DOI Crossref
The Dynamic Transcriptional Cell Atlas of Testis Development during Human Puberty.
Guo J, Nie X, Giebler M, ..., Hotaling JM, Cairns BR
Cell Stem Cell 26 (2) 262-276.e4 [2020-02-06; online 2020-01-09]
PubMed DOI Crossref
Regulation of lipid saturation without sensing membrane fluidity.
Ballweg S, Sezgin E, Doktorova M, ..., Hummer G, Ernst R
Nat Commun 11 (1) 756 [2020-02-06; online 2020-02-06]
DDLS Fellow Erdinc Sezgin Milka Doktorova SciLifeLab Fellow
PubMed DOI Crossref
Correction: A patient-derived xenograft pre-clinical trial reveals treatment responses and a resistance mechanism to karonudib in metastatic melanoma.
Einarsdottir BO, Karlsson J, Söderberg EMV, ..., Helleday T, Nilsson JA
Cell Death Dis 11 (2) 99 [2020-02-06; online 2020-02-06]
PubMed DOI Crossref
Clinicopathological features and prognostic value of SOX11 in childhood acute lymphoblastic leukemia.
Grönroos T, Mäkinen A, Laukkanen S, ..., Heinäniemi M, Lohi O
Sci Rep 10 (1) 2043 [2020-02-06; online 2020-02-06]
PubMed DOI Crossref
Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig.
Rubanova Y, Shi R, Harrigan CF, ..., Morris QD, PCAWG Consortium
Nat Commun 11 (1) 731 [2020-02-05; online 2020-02-05]
PubMed DOI Crossref
Pathway and network analysis of more than 2500 whole cancer genomes.
Reyna MA, Haan D, Paczkowska M, ..., Raphael BJ, PCAWG Consortium
Nat Commun 11 (1) 729 [2020-02-05; online 2020-02-05]
PubMed DOI Crossref
Integrative pathway enrichment analysis of multivariate omics data.
Paczkowska M, Barenboim J, Sintupisut N, ..., Reimand J, PCAWG Consortium
Nat Commun 11 (1) 735 [2020-02-05; online 2020-02-05]
PubMed DOI Crossref
Inferring structural variant cancer cell fraction.
Cmero M, Yuan K, Ong CS, ..., Macintyre G, PCAWG Consortium
Nat Commun 11 (1) 730 [2020-02-05; online 2020-02-05]
PubMed DOI Crossref
High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations.
Zhang Y, Chen F, Fonseca NA, ..., Creighton CJ, PCAWG Consortium
Nat Commun 11 (1) 736 [2020-02-05; online 2020-02-05]
PubMed DOI Crossref
Genomic footprints of activated telomere maintenance mechanisms in cancer.
Sieverling L, Hong C, Koser SD, ..., Feuerbach L, PCAWG Consortium
Nat Commun 11 (1) 733 [2020-02-05; online 2020-02-05]
PubMed DOI Crossref
Expression and regulation of FRMD6 in mouse DRG neurons and spinal cord after nerve injury.
Lyu C, Lyu GW, Mulder J, ..., Hökfelt T, Sten Shi TJ
Sci Rep 10 (1) 1880 [2020-02-05; online 2020-02-05]
PubMed DOI Crossref
Divergent mutational processes distinguish hypoxic and normoxic tumours.
Bhandari V, Li CH, Bristow RG, Boutros PC, PCAWG Consortium
Nat Commun 11 (1) 737 [2020-02-05; online 2020-02-05]
PubMed DOI Crossref
Direct stimulation of angiotensin II type 2 receptor reduces nitric oxide production in lipopolysaccharide treated mouse macrophages.
Isaksson R, Casselbrant A, Elebring E, ..., Larhed M, Fändriks L
Eur. J. Pharmacol. 868 (-) 172855 [2020-02-05; online 2019-12-16]
PubMed DOI Crossref
Combined burden and functional impact tests for cancer driver discovery using DriverPower.
Shuai S, PCAWG Drivers and Functional Interpretation Working Group , Gallinger S, Stein LD, PCAWG Consortium
Nat Commun 11 (1) 734 [2020-02-05; online 2020-02-05]
PubMed DOI Crossref
Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis.
Carlevaro-Fita J, Lanzós A, Feuerbach L, ..., Johnson R, PCAWG Consortium
Commun Biol 3 (1) 56 [2020-02-05; online 2020-02-05]
PubMed DOI Crossref
A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns.
Jiao W, Atwal G, Polak P, ..., Stein LD, PCAWG Consortium
Nat Commun 11 (1) 728 [2020-02-05; online 2020-02-05]
PubMed DOI Crossref
Molecular Insights from Conformational Ensembles via Machine Learning.
Fleetwood O, Kasimova MA, Westerlund AM, Delemotte L
Biophys. J. 118 (3) 765-780 [2020-02-04; online 2019-12-21]
Lucie Delemotte SciLifeLab Fellow
DOI Crossref
MetaCNV - a consensus approach to infer accurate copy numbers from low coverage data
Friedrich S, Barbulescu R, Helleday T, Sonnhammer EL
- - (-) - [2020-02-04; online 2020-02-04]
PubMed DOI Crossref
Abundance and diversity of resistomes differ between healthy human oral cavities and gut.
Carr VR, Witherden EA, Lee S, ..., Gomez-Cabrero D, Moyes DL
Nat Commun 11 (1) 693 [2020-02-04; online 2020-02-04]
Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
Immunometabolic Network Interactions of the Kynurenine Pathway in Cutaneous Malignant Melanoma.
Rad Pour S, Morikawa H, Kiani NA, ..., Eriksson H, Tegnér J
Front Oncol 10 (-) 51 [2020-02-03; online 2020-02-03]
DOI Crossref
Hybridization-based In Situ Sequencing (HybISS): spatial transcriptomic detection in human and mouse brain tissue
Gyllborg D, Langseth CM, Qian X, ..., Lein ES, Nilsson M
- - (-) - [2020-02-03; online 2020-02-03]
PubMed DOI Crossref
Genomic regions under selection in the feralization of the dingoes.
Zhang SJ, Wang GD, Ma P, ..., Savolainen P, Zhang YP
Nat Commun 11 (1) 671 [2020-02-03; online 2020-02-03]
PubMed DOI Crossref
Extensive dissemination and intraclonal maturation of HIV Env vaccine-induced B cell responses.
Phad GE, Pushparaj P, Tran K, ..., Wyatt RT, Karlsson Hedestam GB
J. Exp. Med. 217 (2) - [2020-02-03; online 2019-11-11]
DOI Crossref
Analysis of translating mitoribosome reveals functional characteristics of translation in mitochondria of fungi
Itoh Y, Naschberger A, Mortezaei N, Herrmann JM, Amunts A
bioRxiv - (-) - [2020-02-02; online 2020-02-02]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
miComplete: weighted quality evaluation of assembled microbial genomes.
Hugoson E, Lam WT, Guy L
Bioinformatics 36 (3) 936-937 [2020-02-01; online 2019-09-11]
PubMed DOI Crossref
Unification of miRNA and isomiR research: the mirGFF3 format and the mirtop API.
Desvignes T, Loher P, Eilbeck K, ..., Halushka MK, Pantano L
Bioinformatics 36 (3) 698-703 [2020-02-01; online 2019-09-11]
Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
Rethinking microbial symbioses.
Tamarit D, Andersson SGE
FEMS Microbiol. Lett. 367 (3) - [2020-02-01; online 2020-03-21]
PubMed DOI Crossref
Purifying Selection in Corvids Is Less Efficient on Islands.
Kutschera VE, Poelstra JW, Botero-Castro F, ..., Wiberg RAW, Wolf JBW
Mol. Biol. Evol. 37 (2) 469-474 [2020-02-01; online 2019-10-22]
PubMed DOI Crossref
Macrocyclic peptidomimetics as inhibitors of insulin-regulated aminopeptidase (IRAP).
Barlow N, Vanga SR, Sävmarker J, ..., Chai SY, Thompson PE
RSC Med Chem 11 (2) 234-244 [2020-02-01; online 2020-01-08]
PubMed DOI Crossref
Along the Indian Ocean Coast: Genomic Variation in Mozambique Provides New Insights into the Bantu Expansion.
Semo A, Gayà-Vidal M, Fortes-Lima C, ..., Schlebusch C, Rocha J
Mol. Biol. Evol. 37 (2) 406-416 [2020-02-01; online 2019-10-09]
PubMed DOI Crossref
A rapid and accurate method to quantify neurite outgrowth from cell and tissue cultures: Two image analytic approaches using adaptive thresholds or machine learning.
Ossinger A, Bajic A, Pan S, ..., Hailer NP, Schizas N
J Neurosci Methods 331 (-) 108522 [2020-02-01; online 2019-11-14]
PubMed DOI Crossref
Using personalized immune-humanized xenograft mouse models to predict immune checkpoint responses in malignant melanoma: potential and hurdles.
Helleday T
Ann. Oncol. 31 (2) 167-168 [2020-02-00; online 2020-01-22]
PubMed DOI Crossref
The repertoire of mutational signatures in human cancer.
Alexandrov LB, Kim J, Haradhvala NJ, ..., Stratton MR, PCAWG Consortium
Nature 578 (7793) 94-101 [2020-02-00; online 2020-02-05]
PubMed DOI Crossref
The molecular basis for sugar import in malaria parasites.
Qureshi AA, Suades A, Matsuoka R, ..., Delemotte L, Drew D
Nature 578 (7794) 321-325 [2020-02-00; online 2020-01-29]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
The evolutionary history of 2,658 cancers.
Gerstung M, Jolly C, Leshchiner I, ..., Van Loo P, PCAWG Consortium
Nature 578 (7793) 122-128 [2020-02-00; online 2020-02-06]
PubMed DOI Crossref
The antimalarial drug amodiaquine stabilizes p53 through ribosome biogenesis stress, independently of its autophagy-inhibitory activity.
Espinoza JA, Zisi A, Kanellis DC, ..., Lindström MS, Bartek J
Cell Death Differ. 27 (2) 773-789 [2020-02-00; online 2019-07-08]
PubMed DOI Crossref
Systematic review with meta-analysis: the risks of proton pump inhibitors during pregnancy.
Li CM, Zhernakova A, Engstrand L, Wijmenga C, Brusselaers N
Aliment. Pharmacol. Ther. 51 (4) 410-420 [2020-02-00; online 2020-01-07]
PubMed DOI Crossref
Selective sweeps on novel and introgressed variation shape mimicry loci in a butterfly adaptive radiation.
Moest M, Van Belleghem SM, James JE, ..., Steiner FM, Jiggins CD
PLoS Biol. 18 (2) e3000597 [2020-02-00; online 2020-02-06]
DDLS Fellow Jennifer James
PubMed DOI Crossref
Season of birth, childhood asthma and allergy in a nationwide cohort-Mediation through lower respiratory infections.
Almqvist C, Ekberg S, Rhedin S, ..., Fall T, Lundholm C
Clin. Exp. Allergy 50 (2) 222-230 [2020-02-00; online 2019-12-28]
PubMed DOI Crossref
Revealing the Regional Localization and Differential Lung Retention of Inhaled Compounds by Mass Spectrometry Imaging.
Hamm GR, Bäckström E, Brülls M, ..., Fridén M, Goodwin RJA
J Aerosol Med Pulm Drug Deliv 33 (1) 43-53 [2020-02-00; online 2019-07-31]
PubMed DOI Crossref
Response to Letter to the Editor by Bartoloni et al: 'Interplay of anti-SSA/SSB status and hypertension in determining cardiovascular risk in primary Sjögren's syndrome'.
Mofors J, Wahren-Herlenius M, Nordmark G
J. Intern. Med. 287 (2) 216-217 [2020-02-00; online 2019-11-05]
PubMed DOI Crossref
Repurposing human kinase inhibitors to create an antibiotic active against drug-resistant Staphylococcus aureus, persisters and biofilms.
Le P, Kunold E, Macsics R, ..., Medina E, Sieber SA
Nat Chem 12 (2) 145-158 [2020-02-00; online 2019-12-16]
PubMed DOI Crossref
Publisher Correction: Analysis of the Human Protein Atlas Image Classification competition.
Ouyang W, Winsnes CF, Hjelmare M, ..., Kappel C, Lundberg E
Nat. Methods 17 (2) 241 [2020-02-00; online 2020-01-24]
DDLS Fellow Wei Ouyang
DOI Crossref
Protein crystallization benefits from the rough well surface of a 48-well polystyrene microplate
Ye ZY, Broströmer E, Nan J, ..., Liu ZJ, Su XD
Journal of Crystal Growth 532 (-) 125425 [2020-02-00; online 2020-02-00]
PubMed DOI Crossref
Plasma Lipidome and Prediction of Type 2 Diabetes in the Population-Based Malmö Diet and Cancer Cohort.
Fernandez C, Surma MA, Klose C, ..., Simons K, Melander O
Diabetes Care 43 (2) 366-373 [2020-02-00; online 2019-12-08]
PubMed DOI Crossref
Perspective on CETSA Literature: Toward More Quantitative Data Interpretation.
Seashore-Ludlow B, Axelsson H, Lundbäck T
SLAS Discov 25 (2) 118-126 [2020-02-00; online 2019-10-30]
PubMed DOI Crossref
Patterns of somatic structural variation in human cancer genomes.
Li Y, Roberts ND, Wala JA, ..., Campbell PJ, PCAWG Consortium
Nature 578 (7793) 112-121 [2020-02-00; online 2020-02-05]
PubMed DOI Crossref
Pan-cancer analysis of whole genomes.
ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium
Nature 578 (7793) 82-93 [2020-02-00; online 2020-02-05]
PubMed DOI Crossref
OSU-6162, a Sigma1R Ligand in Low Doses, Can Further Increase the Effects of Cocaine Self-Administration on Accumbal D2R Heteroreceptor Complexes.
Borroto-Escuela DO, Romero-Fernandez W, Wydra K, ..., Filip M, Fuxe K
Neurotox Res 37 (2) 433-444 [2020-02-00; online 2019-11-28]
PubMed DOI Crossref
NCF1-339 polymorphism is associated with altered formation of neutrophil extracellular traps, high serum interferon activity and antiphospholipid syndrome in systemic lupus erythematosus.
Linge P, Arve S, Olsson LM, ..., Holmdahl R, Bengtsson A
Ann. Rheum. Dis. 79 (2) 254-261 [2020-02-00; online 2019-11-08]
DOI Crossref
Mapping pH-Dependent State Transitions of a Pentameric Ligand-gated Ion Channel through Markov State Modeling
Bergh C, Orellana L, Heusser SA, Howard RJ, Lindahl E
Biophysical Journal 118 (3) 191a [2020-02-00; online 2020-02-00]
PubMed DOI Crossref
Is evolution predictable? Quantitative genetics under complex genotype-phenotype maps.
Milocco L, Salazar-Ciudad I
Evolution 74 (2) 230-244 [2020-02-00; online 2020-01-03]
DDLS Fellow Lisandro Milocco
PubMed DOI Crossref
Increased risk of multiple myeloma in primary Sjögren's syndrome is limited to individuals with Ro/SSA and La/SSB autoantibodies.
Mofors J, Björk A, Smedby KE, ..., Nordmark G, Wahren-Herlenius M
Ann. Rheum. Dis. 79 (2) 307-308 [2020-02-00; online 2019-11-06]
PubMed DOI Crossref
Handling ties in continuous outcomes for confounder adjustment with rank-ordered logit and its application to ordinal outcomes.
Ning Y, Tan CS, Maraki A, ..., Reilly M, Støer NC
Stat Methods Med Res 29 (2) 437-454 [2020-02-00; online 2019-04-03]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Growth differentiation factor 15 (GDF-15) is a potential biomarker of both diabetic kidney disease and future cardiovascular events in cohorts of individuals with type 2 diabetes: a proteomics approach.
Carlsson AC, Nowak C, Lind L, ..., Fall T, Ärnlöv J
Ups. J. Med. Sci. 125 (1) 37-43 [2020-02-00; online 2019-12-05]
PubMed DOI Crossref
Genomic basis for RNA alterations in cancer.
PCAWG Transcriptome Core Group , Calabrese C, Davidson NR, ..., Zhang Z, PCAWG Consortium
Nature 578 (7793) 129-136 [2020-02-00; online 2020-02-05]
PubMed DOI Crossref
Genomic and transcriptomic features of dermatofibrosarcoma protuberans: Unusual chromosomal origin of the COL1A1-PDGFB fusion gene and synergistic effects of amplified regions in tumor development.
Köster J, Arbajian E, Viklund B, ..., Mandahl N, Mertens F
Cancer Genet 241 (-) 34-41 [2020-02-00; online 2019-12-10]
DOI Crossref
Environmental impacts and limitations of third‐generation biobutanol: Life cycle assessment of ‐butanol produced by genetically engineered cyanobacteria
Nilsson A, Shabestary K, Brandão M, Hudson EP
Journal of Industrial Ecology 24 (1) 205-216 [2020-02-00; online 2019-04-00]
Paul Hudson SciLifeLab Fellow
PubMed DOI Crossref
Digital Rolling Circle Amplification-Based Detection of Ebola and Other Tropical Viruses.
Ciftci S, Neumann F, Abdurahman S, ..., Nilsson M, Madaboosi N
J Mol Diagn 22 (2) 272-283 [2020-02-00; online 2019-12-16]
PubMed DOI Crossref
Concentration-response evaluation of ToxCast compounds for multivariate activity patterns of neural network function.
Kosnik MB, Strickland JD, Marvel SW, ..., Reif DM, Shafer TJ
Arch. Toxicol. 94 (2) 469-484 [2020-02-00; online 2019-12-10]
PubMed DOI Crossref
Comparison of a Deep Learning Risk Score and Standard Mammographic Density Score for Breast Cancer Risk Prediction.
Dembrower K, Liu Y, Azizpour H, ..., Lindholm P, Strand F
Radiology 294 (2) 265-272 [2020-02-00; online 2019-12-17]
DOI Crossref
Clinicopathological Characteristic of PD-L1 in Gastric Cancer Patients
Polom K, Williams C, Marano L, ..., Marrelli D, Roviello F
European Journal of Surgical Oncology 46 (2) e148 [2020-02-00; online 2020-02-00]
PubMed DOI Crossref
Classification of clear cell renal cell carcinoma based on PKM alternative splicing.
Li X, Turanli B, Juszczak K, ..., Zhang C, Mardinoglu A
Heliyon 6 (2) e03440 [2020-02-00; online 2020-02-19]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
DOI Crossref
Calmodulin Functionally Couples the KCNQ1 Channel Voltage-Sensing and Pore Domains
Kang PW, Westerlund AM, Shi J, ..., Delemotte L, Cui J
Biophysical Journal 118 (3) 332a-333a [2020-02-00; online 2020-02-00]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Biochemical and biophysical comparison of human and mouse beta-2 microglobulin reveals the molecular determinants of low amyloid propensity.
Achour A, Broggini L, Han X, ..., Camilloni C, Ricagno S
FEBS J. 287 (3) 546-560 [2020-02-00; online 2019-08-28]
PubMed DOI Crossref
Artificial intelligence for diagnosis and grading of prostate cancer in biopsies: a population-based, diagnostic study.
Ström P, Kartasalo K, Olsson H, ..., Egevad L, Eklund M
Lancet Oncol 21 (2) 222-232 [2020-02-00; online 2020-01-08]
DDLS Fellow Kimmo Kartasalo
PubMed DOI Crossref
Analysis of the genetic variants associated with circulating levels of sgp130. Results from the IMPROVE study.
Bonomi A, Veglia F, Baldassarre D, ..., Gigante B, on behalf of the IMPROVE study group
Genes Immun. 21 (2) 100-108 [2020-02-00; online 2020-01-14]
PubMed DOI Crossref
Analyses of non-coding somatic drivers in 2,658 cancer whole genomes.
Rheinbay E, Nielsen MM, Abascal F, ..., Getz G, PCAWG Consortium
Nature 578 (7793) 102-111 [2020-02-00; online 2020-02-05]
PubMed DOI Crossref
ALDH1A1-related stemness in high-grade serous ovarian cancer is a negative prognostic indicator but potentially targetable by EGFR/mTOR-PI3K/aurora kinase inhibitors.
Kaipio K, Chen P, Roering P, ..., Hautaniemi S, Carpén O
J. Pathol. 250 (2) 159-169 [2020-02-00; online 2019-12-03]
PubMed DOI Crossref
A window into lysogeny: revealing temperate phage biology with transcriptomics.
Owen SV, Canals R, Wenner N, ..., Kröger C, Hinton JCD
Microb Genom 6 (2) - [2020-02-00; online 2020-02-05]
PubMed DOI Crossref
A Multi-Cohort Metabolomics Analysis Discloses Sphingomyelin (32:1) Levels to be Inversely Related to Incident Ischemic Stroke.
Lind L, Salihovic S, Ganna A, ..., Ingelsson E, Ärnlöv J
J Stroke Cerebrovasc Dis 29 (2) 104476 [2020-02-00; online 2019-12-02]
PubMed DOI Crossref
A Comprehensive Sequencing-Based Analysis of Allelic Methylation Patterns in Hemostatic Genes in Human Liver.
Olsson Lindvall M, Davila Lopez M, Klasson S, ..., Stanne TM, Jern C
Thromb. Haemost. 120 (2) 229-242 [2020-02-00; online 2019-12-30]
DOI Crossref
In situ sequencing for RNA analysis in tissue sections v2
Yokota C, Gyllborg D, Nilsson M
- - (-) - [2020-01-31; online 2020-01-31]
DOI Crossref
CopyMix: Mixture Model Based Single-Cell Clustering and Copy Number Profiling using Variational Inference
Safinianaini N, P. E. de Souza C, Roth A, ..., Toosi H, Lagergren J
- - (-) - [2020-01-31; online 2020-01-31]
DOI Crossref
Approaches for Containerized Scientific Workflows in Cloud Environments with Applications in Life Science
Spjuth O, Capuccini M, Carone M, ..., Kultima K, Lampa S
- - (-) - [2020-01-31; online 2020-01-31]
DOI Crossref
Structural basis for the increased processivity of D-family DNA polymerases in complex with PCNA
Madru C, Raia P, Hugonneau-Beaufet I, ..., Carroni M, Sauguet L
- - (-) - [2020-01-30; online 2020-01-30]
DOI Crossref
Mapping the nucleolar proteome reveals a spatiotemporal organization related to intrinsic protein disorder
Stenström L, Mahdessian D, Gnann C, ..., Thul PJ, Lundberg E
bioRxiv - (-) - [2020-01-30; online 2020-01-30]
DDLS Fellow Wei Ouyang
DOI Crossref
Evolution from adherent to suspension – systems biology of HEK293 cell line development
Malm M, Saghaleyni R, Lundqvist M, ..., Nielsen J, Rockberg J
- - (-) - [2020-01-30; online 2020-01-30]
PubMed DOI Crossref
Sarek: A portable workflow for whole-genome sequencing analysis of germline and somatic variants.
Garcia M, Juhos S, Larsson M, ..., Käller M, Nystedt B
F1000Res 9 (-) 63 [2020-01-29; online 2020-01-29]
DOI Crossref
Sarek: A portable workflow for whole-genome sequencing analysis of germline and somatic variants
Garcia M, Juhos S, Larsson M, ..., Käller M, Nystedt B
F1000Res 9 (-) 63 [2020-01-29; online 2020-01-29]
PubMed DOI Crossref
Phylogenomics and biogeography of the world's thrushes (Aves, Turdus): new evidence for a more parsimonious evolutionary history.
Batista R, Olsson U, Andermann T, ..., Ribas CC, Antonelli A
Proc. Biol. Sci. 287 (1919) 20192400 [2020-01-29; online 2020-01-22]
DDLS Fellow Tobias Andermann
DOI Crossref
Mechanism of DNA surface exploration and operator bypassing during target search
Marklund E, van Oosten B, Mao G, ..., Elf J, Deindl S
- - (-) - [2020-01-29; online 2020-01-29]
Daniel Globisch SciLifeLab Fellow Sebastian Deindl
PubMed DOI Crossref
Author Correction: ATAC-seq reveals alterations in open chromatin in pancreatic islets from subjects with type 2 diabetes.
Bysani M, Agren R, Davegårdh C, ..., Bacos K, Ling C
Sci Rep 10 (1) 1744 [2020-01-29; online 2020-01-29]
PubMed DOI Crossref
Immune profiles in acute myeloid leukemia bone marrow associate with patient age, T-cell receptor clonality, and survival.
Brück O, Dufva O, Hohtari H, ..., Pellinen T, Mustjoki S
Blood Adv 4 (2) 274-286 [2020-01-28; online 2020-01-23]
PubMed DOI Crossref
Exploring the therapeutic potential of modern and ancestral phenylalanine/tyrosine ammonia-lyases as supplementary treatment of hereditary tyrosinemia.
Hendrikse NM, Holmberg Larsson A, Svensson Gelius S, ..., Nordling E, Syrén PO
Sci Rep 10 (1) 1315 [2020-01-28; online 2020-01-28]
PubMed DOI Crossref
Building de novo reference genome assemblies of complex eukaryotic microorganisms from single nuclei.
Montoliu-Nerin M, Sánchez-García M, Bergin C, ..., Johannesson H, Rosling A
Sci Rep 10 (1) 1303 [2020-01-28; online 2020-01-28]
PubMed DOI Crossref
Boosting Natural Killer Cell-Mediated Targeting of Sarcoma Through DNAM-1 and NKG2D.
Sayitoglu EC, Georgoudaki AM, Chrobok M, ..., Sutlu T, Duru AD
Front Immunol 11 (-) 40 [2020-01-28; online 2020-01-28]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Making Soup: Preparing and Validating Models of the Bacterial Cytoplasm for Molecular Simulation.
Oliveira Bortot L, Bashardanesh Z, van der Spoel D
J Chem Inf Model 60 (1) 322-331 [2020-01-27; online 2019-12-19]
PubMed DOI Crossref
Population Genomics of Transitions to Selfing in Brassicaceae Model Systems.
Mattila TM, Laenen B, Slotte T
Methods in molecular biology (Clifton, N.J.) 2090 (-) 269-287 [2020-01-25; online 2020-01-25]
SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Extracellular Vesicles Released From the Skin Commensal Yeast Malassezia sympodialis Activate Human Primary Keratinocytes.
Vallhov H, Johansson C, Veerman RE, Scheynius A
Front. Cell. Infect. Microbiol. 10 (-) 6 [2020-01-24; online 2020-01-24]
PubMed DOI Crossref
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D.
Kennedy SA, Jarboui MA, Srihari S, ..., Lynn DJ, Kolch W
Nat Commun 11 (1) 499 [2020-01-24; online 2020-01-24]
PubMed DOI Crossref
Estimating Detection Limits of Potentiometric DNA Sensors Using Surface Plasmon Resonance Analyses.
Xu X, Makaraviciute A, Abdurakhmanov E, ..., Nyholm L, Zhang Z
ACS Sens 5 (1) 217-224 [2020-01-24; online 2019-12-23]
PubMed DOI Crossref
An optochemical tool for light-induced dissociation of adherens junctions to control mechanical coupling between cells.
Ollech D, Pflästerer T, Shellard A, ..., Wombacher R, Cavalcanti-Adam EA
Nat Commun 11 (1) 472 [2020-01-24; online 2020-01-24]
PubMed DOI Crossref
The Medical Genome Reference Bank contains whole genome and phenotype data of 2570 healthy elderly.
Pinese M, Lacaze P, Rath EM, ..., Dinger ME, Thomas DM
Nat Commun 11 (1) 435 [2020-01-23; online 2020-01-23]
DOI Crossref
Improved computational analysis of ribosome dynamics from 5’P degradome data using fivepeseq
Nersisyan L, Ropat M, Pelechano V
- - (-) - [2020-01-23; online 2020-01-23]
SciLifeLab Fellow
DOI Crossref
Human immune system variation during one year
Lakshmikanth T, Muhammad SA, Olin A, ..., Uhlen M, Brodin P
- - (-) - [2020-01-23; online 2020-01-23]
PubMed DOI Crossref
Effect of TOP2A and ERCC1 gene polymorphisms on the efficacy and toxicity of cisplatin and etoposide-based chemotherapy in small cell lung cancer patients.
Nicoś M, Rolska-Kopińska A, Krawczyk P, ..., Szczyrek M, Milanowski J
Arch Med Sci 17 (2) 474-480 [2020-01-23; online 2020-01-23]
PubMed DOI Crossref
Docking Finds GPCR Ligands in Dark Chemical Matter.
Ballante F, Rudling A, Zeifman A, ..., Loza MI, Carlsson J
J Med Chem 63 (2) 613-620 [2020-01-23; online 2020-01-13]
Andreas Luttens DDLS Fellow Jens Carlsson SciLifeLab Fellow
DOI Crossref
Cancer-associated HIF-2α impacts trunk neural crest stemness
Mohlin S, Persson CU, Fredlund E, ..., Hammarlund E, Bronner ME
- - (-) - [2020-01-23; online 2020-01-23]
PubMed DOI Crossref
Structure-Activity Relationships (SARs) of α-Ketothioamides as Inhibitors of Phosphoglycerate Dehydrogenase (PHGDH).
Spillier Q, Ravez S, Unterlass J, ..., Feron O, Frédérick R
Pharmaceuticals (Basel, Switzerland) 13 (2) - [2020-01-22; online 2020-01-22]
PubMed DOI Crossref
Paenibacillus odorifer, the Predominant Paenibacillus Species Isolated from Milk in the United States, Demonstrates Genetic and Phenotypic Conservation of Psychrotolerance but Clade-Associated Differences in Nitrogen Metabolic Pathways.
Beno SM, Cheng RA, Orsi RH, ..., Martin NH, Wiedmann M
mSphere 5 (1) - [2020-01-22; online 2020-01-22]
DDLS Fellow Laura Carroll
PubMed DOI Crossref
Characterization of virus-mediated immunogenic cancer cell death and the consequences for oncolytic virus-based immunotherapy of cancer.
Ma J, Ramachandran M, Jin C, ..., Yu D, Essand M
Cell Death Dis 11 (1) 48 [2020-01-22; online 2020-01-22]
PubMed DOI Crossref
On the Long and Winding Road to a Perfect Membrane Model.
Doktorova M
Biophys. J. 118 (2) 273-275 [2020-01-21; online 2019-11-28]
DDLS Fellow Milka Doktorova
DOI Crossref
Faculty Opinions recommendation of Structure and activation mechanism of the BBSome membrane protein trafficking complex.
Amunts A
- - (-) - [2020-01-21; online 2020-01-18]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Fabrication of Silicon Microfluidic Chips for Acoustic Particle Focusing Using Direct Laser Writing.
Fornell A, Söderbäck P, Liu Z, De Albuquerque Moreira M, Tenje M
Micromachines (Basel) 11 (2) - [2020-01-21; online 2020-01-21]
PubMed DOI Crossref
Transcriptome analysis of fibroblasts from schizophrenia patients reveals differential expression of schizophrenia-related genes.
Etemadikhah M, Niazi A, Wetterberg L, Feuk L
Sci Rep 10 (1) 630 [2020-01-20; online 2020-01-20]
PubMed DOI Crossref
Loss of centromere function drives karyotype evolution in closely related Malassezia species.
Sankaranarayanan SR, Ianiri G, Coelho MA, ..., Heitman J, Sanyal K
Elife 9 (-) - [2020-01-20; online 2020-01-20]
DOI Crossref
Creating supported plasma membrane bilayers using acoustic pressure
Sezgin E, Carugo D, Levental I, Stride E, Eggeling C
- - (-) - [2020-01-20; online 2020-01-20]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Augmentation of Bri2 molecular chaperone activity against amyloid-β reduces neurotoxicity in mouse hippocampus in vitro.
Chen G, Andrade-Talavera Y, Tambaro S, ..., Abelein A, Johansson J
Commun Biol 3 (1) 32 [2020-01-20; online 2020-01-20]
PubMed DOI Crossref
Menstrual Hygiene Preparedness Among Schools in India: A Systematic Review and Meta-Analysis of System-and Policy-Level Actions.
Sharma S, Mehra D, Brusselaers N, Mehra S
Int J Environ Res Public Health 17 (2) - [2020-01-19; online 2020-01-19]
DOI Crossref
Author response: Loss of centromere function drives karyotype evolution in closely related Malassezia species
Sankaranarayanan SR, Ianiri G, Coelho MA, ..., Heitman J, Sanyal K
- - (-) - [2020-01-19; online 2020-01-19]
PubMed DOI Crossref
Evidence of altered mucosa-associated and fecal microbiota composition in patients with Irritable Bowel Syndrome.
Sundin J, Aziz I, Nordlander S, ..., Simrén M, Öhman L
Sci Rep 10 (1) 593 [2020-01-17; online 2020-01-17]
DDLS Fellow Luisa Hugerth
DOI Crossref
Impact of nanoscale hindrances on the relationship between lipid packing and diffusion in model membranes
Beckers D, Urbancic D, Sezgin E
- - (-) - [2020-01-16; online 2020-01-16]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Novel anti-Alzheimer phenol-lipoyl hybrids: Synthesis, physico-chemical characterization, and biological evaluation.
Pagoni A, Marinelli L, Di Stefano A, ..., Vassiliou S, Cacciatore I
Eur J Med Chem 186 (-) 111880 [2020-01-15; online 2019-11-12]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Linked-read sequencing enables haplotype-resolved resequencing at population scale
Lutgen D, Ritter R, Olsen RA, ..., Suh A, Burri R
- - (-) - [2020-01-15; online 2020-01-15]
PubMed DOI Crossref
Spatiotemporal mapping of RNA editing in the developing mouse brain using in situ sequencing reveals regional and cell-type-specific regulation.
Lundin E, Wu C, Widmark A, ..., Öhman M, Nilsson M
BMC Biol. 18 (1) 6 [2020-01-14; online 2020-01-14]
PubMed DOI Crossref
Identification and transfer of spatial transcriptomics signatures for cancer diagnosis.
Yoosuf N, Navarro JF, Salmén F, Ståhl PL, Daub CO
Breast Cancer Res. 22 (1) 6 [2020-01-13; online 2020-01-13]
PubMed DOI Crossref
A set of monomeric near-infrared fluorescent proteins for multicolor imaging across scales.
Matlashov ME, Shcherbakova DM, Alvelid J, ..., Testa I, Verkhusha VV
Nat Commun 11 (1) 239 [2020-01-13; online 2020-01-13]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
A regulatory role for CHD2 in myelopoiesis.
Shahin Varnoosfaderani F, Palau A, Dong W, ..., Svensson JP, Lennartsson A
Epigenetics 15 (6-7) 702-714 [2020-01-10; online 2020-01-10]
DOI Crossref
Three dimensional parallelized RESOLFT nanoscopy for volumetric live cell imaging
Bodén A, Pennacchietti F, Testa I
- - (-) - [2020-01-09; online 2020-01-09]
Ilaria Testa SciLifeLab Fellow
DOI Crossref
Stable stimulated emission depletion imaging of extended sample regions
Alvelid J, Testa I
J. Phys. D: Appl. Phys. 53 (2) 024001 [2020-01-09; online 2019-10-25]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure.
Shah S, Henry A, Roselli C, ..., Swerdlow DI, Lumbers RT
Nat Commun 11 (1) 163 [2020-01-09; online 2020-01-09]
PubMed DOI Crossref
MirGeneDB 2.0: the metazoan microRNA complement.
Fromm B, Domanska D, Høye E, ..., Friedländer MR, Peterson KJ
Nucleic Acids Res. 48 (D1) D132-D141 [2020-01-08; online 2019-10-11]
Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
MirGeneDB 2.0: the metazoan microRNA complement.
Fromm B, Domanska D, Høye E, ..., Friedländer MR, Peterson KJ
Nucleic Acids Res. 48 (D1) D1172 [2020-01-08; online 2019-10-24]
Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
DisProt: intrinsic protein disorder annotation in 2020.
Hatos A, Hajdu-Soltész B, Monzon AM, ..., Tosatto SCE, Piovesan D
Nucleic Acids Res. 48 (D1) D269-D276 [2020-01-08; online 2019-11-13]
PubMed DOI Crossref
DNA methylation changes in Down syndrome derived neural iPSCs uncover co-dysregulation of ZNF and HOX3 families of transcription factors.
Laan L, Klar J, Sobol M, ..., Schuster J, Dahl N
Clin Epigenetics 12 (1) 9 [2020-01-08; online 2020-01-08]
PubMed DOI Crossref
Evolutionary History, Genomic Adaptation to Toxic Diet, and Extinction of the Carolina Parakeet.
Gelabert P, Sandoval-Velasco M, Serres A, ..., Gilbert MTP, Lalueza-Fox C
Curr. Biol. 30 (1) 108-114.e5 [2020-01-06; online 2019-12-12]
DOI Crossref
ERCC1-XPF Interacts with Topoisomerase IIβ to Facilitate the Repair of Activity-induced DNA Breaks
Chatzinikolaou G, Stratigi K, Agathangelou K, ..., Altmüller J, Garinis GA
- - (-) - [2020-01-03; online 2020-01-03]
PubMed DOI Crossref
The GenTree Dendroecological Collection, tree-ring and wood density data from seven tree species across Europe.
Martínez-Sancho E, Slámová L, Morganti S, ..., Westin J, Fonti P
Sci Data 7 (1) 1 [2020-01-02; online 2020-01-02]
PubMed DOI Crossref
Life-long impairment of glucose homeostasis upon prenatal exposure to psychostimulants.
Korchynska S, Krassnitzer M, Malenczyk K, ..., Hökfelt TG, Harkany T
EMBO J. 39 (1) e100882 [2020-01-02; online 2019-11-21]
DOI Crossref
Faculty Opinions recommendation of Structural basis of DNA targeting by a transposon-encoded CRISPR-Cas system.
Amunts A
- - (-) - [2020-01-02; online 2019-12-22]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Individual cristae within the same mitochondrion display different membrane potentials and are functionally independent.
Amunts A
- - (-) - [2020-01-02; online 2019-12-26]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of In Situ Structure of an Intact Lipopolysaccharide-Bound Bacterial Surface Layer.
Amunts A
- - (-) - [2020-01-02; online 2019-12-27]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Cryo-electron microscopy structures of human oligosaccharyltransferase complexes OST-A and OST-B.
Amunts A
- - (-) - [2020-01-02; online 2019-12-25]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of Analysis of the Human Protein Atlas Image Classification competition.
Amunts A
- - (-) - [2020-01-02; online 2019-12-25]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of A mitochondrial megachannel resides in monomeric F1FO ATP synthase.
Amunts A
- - (-) - [2020-01-02; online 2019-12-26]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
The Mitogenome of Norway Spruce and a Reappraisal of Mitochondrial Recombination in Plants.
Sullivan AR, Eldfjell Y, Schiffthaler B, ..., Street NR, Wang XR
Genome Biol Evol 12 (1) 3586-3598 [2020-01-01; online 2019-11-28]
PubMed DOI Crossref
Protein aggregation in bacteria.
Schramm FD, Schroeder K, Jonas K
FEMS Microbiol Rev 44 (1) 54-72 [2020-01-01; online 2019-10-22]
Kristina Jonas SciLifeLab Fellow
PubMed DOI Crossref
Polymorphism Data Assist Estimation of the Nonsynonymous over Synonymous Fixation Rate Ratio ω for Closely Related Species.
Mugal CF, Kutschera VE, Botero-Castro F, Wolf JBW, Kaj I
Mol. Biol. Evol. 37 (1) 260-279 [2020-01-01; online 2019-09-11]
PubMed DOI Crossref
Hepatitis E virus genotype 3 strains and a plethora of other viruses detected in raw and still in tap water.
Wang H, Kjellberg I, Sikora P, ..., Bergstedt O, Norder H
Water Res 168 (-) 115141 [2020-01-01; online 2019-09-30]
PubMed DOI Crossref
Discovery of Novel Sequences in 1,000 Swedish Genomes.
Eisfeldt J, Mårtensson G, Ameur A, Nilsson D, Lindstrand A
Mol. Biol. Evol. 37 (1) 18-30 [2020-01-01; online 2019-09-29]
PubMed DOI Crossref
Correction to: In Situ Sequencing: A High-Throughput, Multi-Targeted Gene Expression Profiling Technique for Cell Typing in Tissue Sections.
Hilscher MM, Gyllborg D, Yokota C, Nilsson M
Methods in molecular biology (Clifton, N.J.) 2148 (-) C1 [2020-01-01; online 2020-01-01]
PubMed DOI Crossref
Advances in GLP-1 receptor targeting radiolabeled agent development and prospective of theranostics.
Velikyan I, Eriksson O
Theranostics 10 (1) 437-461 [2020-01-01; online 2020-01-01]
Olof Eriksson SciLifeLab Fellow
DOI Crossref
ATR expands embryonic stem cell fate potential in response to replication stress
Atashpaz S, Shams SS, Gonzalez JM, ..., López-Contreras AJ, Costanzo V
- - (-) - [2020-01-01; online 2020-01-01]
PubMed DOI Crossref
Type I IFN system activation in newborns exposed to Ro/SSA and La/SSB autoantibodies in utero.
Hedlund M, Thorlacius GE, Ivanchenko M, ..., Eloranta ML, Wahren-Herlenius M
RMD Open 6 (1) - [2020-01-00; online 2020-01-21]
PubMed DOI Crossref
Time-resolved imaging-based CRISPRi screening.
Camsund D, Lawson MJ, Larsson J, ..., Fange D, Elf J
Nat. Methods 17 (1) 86-92 [2020-01-00; online 2019-11-18]
PubMed DOI Crossref
The vaginal microbiota, human papillomavirus and cervical dysplasia: a systematic review and network meta-analysis.
Norenhag J, Du J, Olovsson M, ..., Engstrand L, Brusselaers N
BJOG 127 (2) 171-180 [2020-01-00; online 2019-07-17]
PubMed DOI Crossref
The Proteome of the Dentate Terminal Zone of the Perforant Path Indicates Presynaptic Impairment in Alzheimer Disease.
Haytural H, Mermelekas G, Emre C, ..., Tjernberg LO, Frykman S
Mol. Cell Proteomics 19 (1) 128-141 [2020-01-00; online 2019-11-07]
PubMed DOI Crossref
The New Tree of Eukaryotes.
Burki F, Roger AJ, Brown MW, Simpson AGB
Trends in Ecology & Evolution 35 (1) 43-55 [2020-01-00; online 2019-10-09]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
The Neuropeptide Y Y2 Receptor Is Coexpressed with Nppb in Primary Afferent Neurons and Y2 Activation Reduces Histaminergic and IL-31-Induced Itch.
Ma H, Gao T, Jakobsson JET, ..., Larhammar D, Lagerström MC
J. Pharmacol. Exp. Ther. 372 (1) 73-82 [2020-01-00; online 2019-11-26]
PubMed DOI Crossref
Publisher Correction: Analysis of the Human Protein Atlas Image Classification competition.
Ouyang W, Winsnes CF, Hjelmare M, ..., Kappel C, Lundberg E
Nat. Methods 17 (1) 115 [2020-01-00; online 2019-12-12]
DDLS Fellow Wei Ouyang
PubMed DOI Crossref
Protein and DNA methylation-based scores as surrogate markers for interferon system activation in patients with primary Sjögren's syndrome.
Björk A, Richardsdotter Andersson E, Imgenberg-Kreuz J, ..., Nordmark G, Wahren-Herlenius M
RMD Open 6 (1) - [2020-01-00; online 2020-01-21]
PubMed DOI Crossref
Promoter polymorphisms of TOP2A and ERCC1 genes as predictive factors for chemotherapy in non-small cell lung cancer patients.
Grenda A, Błach J, Szczyrek M, ..., Sawicki M, Milanowski J
Cancer Med 9 (2) 605-614 [2020-01-00; online 2019-12-03]
PubMed DOI Crossref
Proinflammatory Histidyl-Transfer RNA Synthetase-Specific CD4+ T Cells in the Blood and Lungs of Patients With Idiopathic Inflammatory Myopathies.
Galindo-Feria AS, Albrecht I, Fernandes-Cerqueira C, ..., Malmström V, Lundberg IE
Arthritis & rheumatology (Hoboken, N.J.) 72 (1) 179-191 [2020-01-00; online 2019-11-26]
PubMed DOI Crossref
Probabilistic cell typing enables fine mapping of closely related cell types in situ.
Qian X, Harris KD, Hauling T, ..., Hjerling-Leffler J, Nilsson M
Nat. Methods 17 (1) 101-106 [2020-01-00; online 2019-11-18]
DOI Crossref
Ontogenic succession of thermokarst thaw ponds is linked to dissolved organic matter quality and microbial degradation potential
Peura S, Wauthy M, Simone D, ..., Rautio M, Bertilsson S
Limnol. Oceanogr. 65 (S1) - [2020-01-00; online 2019-10-28]
Sari Peura SciLifeLab Fellow
PubMed DOI Crossref
Nordic OCD & Related Disorders Consortium: Rationale, design, and methods.
Mataix-Cols D, Hansen B, Mattheisen M, ..., Rück C, Crowley JJ
Am. J. Med. Genet. B Neuropsychiatr. Genet. 183 (1) 38-50 [2020-01-00; online 2019-08-19]
DOI Crossref
Non‐cyanobacterial diazotrophs dominate nitrogen‐fixing communities in permafrost thaw ponds
Fernandez L, Bertilsson S, Peura S
Limnol. Oceanogr. 65 (S1) - [2020-01-00; online 2019-08-05]
Sari Peura SciLifeLab Fellow
PubMed DOI Crossref
Medulloblastomics revisited: biological and clinical insights from thousands of patients.
Hovestadt V, Ayrault O, Swartling FJ, ..., Pfister SM, Northcott PA
Nat. Rev. Cancer 20 (1) 42-56 [2020-01-00; online 2019-12-09]
PubMed DOI Crossref
Circadian regulation of phosphodiesterase 6 genes in zebrafish differs between cones and rods: Implications for photopic and scotopic vision.
Abalo XM, Lagman D, Heras G, ..., Eggert J, Larhammar D
Vision Res 166 (-) 43-51 [2020-01-00; online 2019-12-16]
PubMed DOI Crossref
Changes in Proteomic Profiles are Related to Changes in BMI and Fat Distribution During 10 Years of Aging.
Lind L, Figarska S, Sundström J, ..., Ärnlöv J, Ingelsson E
Obesity (Silver Spring) 28 (1) 178-186 [2020-01-00; online 2019-12-05]
PubMed DOI Crossref
Biophysics and the nonlinear dynamics instigated by a special hormone.
Javed S, Sohail A, Asif A, Nutini A
Prog. Biophys. Mol. Biol. 150 (-) 62-66 [2020-01-00; online 2019-05-20]
PubMed DOI Crossref
Biomarkers: to be or not to be.
Yavuz S, Rönnblom L
Ann. Rheum. Dis. 79 (1) e8 [2020-01-00; online 2018-11-10]
PubMed DOI Crossref
Association Between Metformin Use and Risk of Esophageal Squamous Cell Carcinoma in a Population-Based Cohort Study.
Wang QL, Santoni G, Ness-Jensen E, Lagergren J, Xie SH
Am J Gastroenterol 115 (1) 73-78 [2020-01-00; online 2019-12-11]
DDLS Fellow Qiaoli Wang
PubMed DOI Crossref
Acute wheeze-specific gene module shows correlation with vitamin D and asthma medication.
Katayama S, Stenberg Hammar K, Krjutškov K, ..., Kere J, Söderhäll C
Eur. Respir. J. 55 (1) - [2020-01-00; online 2020-01-23]
PubMed DOI Crossref
AI- modelling of molecular identification and feminization of wolbachia infected Aedes aegypti.
Iftikhar M, Iftikhar S, Sohail A, Javed S
Prog. Biophys. Mol. Biol. 150 (-) 104-111 [2020-01-00; online 2019-07-11]
PubMed DOI Crossref
A new opening for orally taken peptide drugs.
Artursson P, Lundquist P
Nat Biomed Eng 4 (1) 12-13 [2020-01-00; online 2020-01-16]
PubMed DOI Crossref
A fieldable electrostatic air sampler enabling tuberculosis detection in bioaerosols.
Rufino de Sousa N, Sandström N, Shen L, ..., Croda J, Rothfuchs AG
Tuberculosis (Edinb) 120 (-) 101896 [2020-01-00; online 2019-12-24]
DOI Crossref
Targeted Editing of Zebrafish Genes to Understand Gene Function and Human Disease Pathology
Rissone A, Ledin J, Burgess SM
- - (-) 637-647 [2020-00-00; online 2020-00-00]
DOI Crossref
Sheep: Domestication
Meadows JRS
- - (-) 9637-9640 [2020-00-00; online 2020-10-26]
DOI Crossref
Screening for High Amounts of SARS-CoV-2 Identifies Pre-Symptomatic Subjects Among Healthy Healthcare Workers
Dillner J, Elfström KM, Blomqvist J, ..., Mühr LSA, Conneryd Lundgren K
SSRN Journal - (-) - [2020-00-00; online 2020-00-00]
DOI Crossref
Proximal Deletion 12q with a New Insight to Growth Retardation
Sobol M, Thuresson AC, Palmberg N, Soussi Zander C
Mol Syndromol 11 (3) 115-124 [2020-00-00; online 2020-04-10]
DOI Crossref
Optofluidic Fiber Component to Separate Micron-Sized Particles Using Elasto-Inertial Focusing
Harish AV, Kumar T, Etcheverry S, ..., Margulis W, Laurell F
- - (-) JTU2C.10 [2020-00-00; online 2020-00-00]
DOI Crossref
List of Contributors
Abdollahi M, Albaqami FF, Alharthy KM, ..., Zambrone FAD, Zayed J
- - (-) xv-xviii [2020-00-00; online 2020-00-00]
DOI Crossref
Inhibition of the Ubiquitin-Proteasome System by a Bioactivatable Prodrug
Giovannucci TA, Salomons FA, Martin Haraldsson M, ..., Johnsen JI, Dantuma N
SSRN Journal - (-) - [2020-00-00; online 2020-00-00]
DOI Crossref
Greece
Apalaki P, Vakonaki E, Tsatsakis AM
- - (-) 205-210 [2020-00-00; online 2020-00-00]
DOI Crossref
GROMEX: A Scalable and Versatile Fast Multipole Method for Biomolecular Simulation
Kohnke B, Ullmann TR, Beckmann A, ..., Dachsel H, Grubmüller H
- - (-) 517-543 [2020-00-00; online 2020-07-31]
DOI Crossref
Fiber Based Optofluidic Micro-Flow Cytometer Collecting Side-Scattered Light
Harish AV, Kumar T, Russom A, Margulis W, Laurell F
- - (-) AW3I.3 [2020-00-00; online 2020-00-00]
DOI Crossref
Divergent Clonal Differentiation Trajectories Establish CD8 <sup>+</sup> Memory T Cell Heterogeneity During Acute Viral Infections in Humans
Mold JE, Modolo L, Hård J, ..., Michaelsson J, Frisén J
SSRN Journal - (-) - [2020-00-00; online 2020-00-00]
DOI Crossref
Discovery of Functional Alternatively Spliced <i>PKM</i> Transcripts in Human Cancers
Li X, Zhang C, Kim W, ..., Uhlen M, Mardinoglu A
- - (-) - [2020-00-00; online 2020-00-00]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
DOI Crossref
Decoupling Inherent Risk and Early Cancer Signs in Image-Based Breast Cancer Risk Models
Liu Y, Azizpour H, Strand F, Smith K
- - (-) 230-240 [2020-00-00; online 2020-09-29]
DOI Crossref
Cryo-EM Structure of Native Human Uromodulin, a Zona Pellucida Module Polymer
Stsiapanava A, Xu C, Brunati M, ..., Wu B, Jovine L
SSRN Journal - (-) - [2020-00-00; online 2020-00-00]
DOI Crossref
Clinical proteomics and molecular pathology
Liotta LA, Davis JB, Couch RD, ..., Petricoin E, Espina V
- - (-) 149-163 [2020-00-00; online 2020-00-00]
DOI Crossref
Circulating miRNA Signature Predicts and Rescues Spaceflight Associated Health Risks
Malkani S, Cekanaviciute E, Mortreux M, ..., Grabham P, Beheshti A
- - (-) - [2020-00-00; online 2020-00-00]
DDLS Fellow Marc Friedländer Marcel Tarbier SciLifeLab Fellow
DOI Crossref
COVID-19 and Beyond: A Call for Action and Audacious Solidarity to All the Citizens and Nations, It Is Humanity’s Fight
Auffray C, Balling R, Blomberg N, ..., Wolkenhauer O, Wouters E
SSRN Journal - (-) - [2020-00-00; online 2020-00-00]
DOI Crossref
Advances in whole genome methylomic sequencing
Nordlund J
- - (-) 213-233 [2020-00-00; online 2020-00-00]
DOI Crossref
Acute Kidney Injury Leading to CKD is Associated with a Persistence of Metabolic Dysfunction and Hypertriglyceridemia
Harzandi A, Bidkhori G, Lee S, ..., Shoaie S, Sharpe C
SSRN Journal - (-) - [2020-00-00; online 2020-00-00]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
DOI Crossref
Acoustic Biosensors for Cell Research
Damiati S
- - (-) 1-32 [2020-00-00; online 2020-03-06]
DOI Crossref
A Novel Method for Reconstructing CT Images in GATE/GEANT4 with Application in Medical Imaging: A Complexity Analysis Approach
Gholami N, Dehshibi MM, Adamatzky A, ..., Fazlali M, Masip D
Journal of Information Processing 28 (0) 161-168 [2020-00-00; online 2020-00-00]
SciLifeLab Data Centre
Publications 9.5.1