Publications 2015

693 publications

Systematic hierarchical coarse-graining with the inverse Monte Carlo method.
Lyubartsev AP, Naômé A, Vercauteren DP, Laaksonen A
J Chem Phys 143 (24) 243120 [2015-12-28; online 2016-01-03]
Fragment-Based Discovery of Subtype-Selective Adenosine Receptor Ligands from Homology Models.
Ranganathan A, Stoddart LA, Hill SJ, Carlsson J
J Med Chem 58 (24) 9578-9590 [2015-12-24; online 2015-12-08]
Evaluation of Intracellular Signaling Downstream Chimeric Antigen Receptors.
Karlsson H, Svensson E, Gigg C, ..., Dotti G, Loskog A
PLoS ONE 10 (12) e0144787 [2015-12-23; online 2015-12-23]
The Urinary Bladder Transcriptome and Proteome Defined by Transcriptomics and Antibody-Based Profiling.
Habuka M, Fagerberg L, Hallström BM, ..., Yamamoto T, Uhlen M
PLoS ONE 10 (12) e0145301 [2015-12-22; online 2015-12-22]
Transcriptome analysis reveals mucin 4 to be highly associated with periodontitis and identifies pleckstrin as a link to systemic diseases.
Lundmark A, Davanian H, Båge T, ..., Lundeberg J, Yucel-Lindberg T
Sci Rep 5 (-) 18475 [2015-12-21; online 2015-12-21]
Genome-wide genetic homogeneity between sexes and populations for human height and body mass index.
Yang J, Bakshi A, Zhu Z, ..., Ingelsson E, Visscher PM
Hum. Mol. Genet. 24 (25) 7445-7449 [2015-12-20; online 2015-10-22]
The ELIXIR channel in F1000Research.
Blomberg N, Oliveira A, Mons B, Persson B, Jonassen I
F1000Res 4 (-) - [2015-12-18; online 2015-12-18]
Exploring water as building bricks in enzyme engineering.
Hendil-Forssell P, Martinelle M, Syrén PO
Chem. Commun. (Camb.) 51 (97) 17221-17224 [2015-12-18; online 2015-10-02]
Cancer Metabolism: A Modeling Perspective.
Ghaffari P, Mardinoglu A, Nielsen J
Front. Physiol. 6 (-) 382 [2015-12-16; online 2015-12-16]
Powerful Populations Respond to Viruses and Vaccines.
Brodin P
Immunity 43 (6) 1035-1037 [2015-12-15; online 2015-12-20]
Oligonucleotide gap-fill ligation for mutation detection and sequencing in situ.
Mignardi M, Mezger A, Qian X, ..., Larsson C, Nilsson M
Nucleic Acids Res. 43 (22) e151 [2015-12-15; online 2015-08-03]
Metagenome-assembled genomes uncover a global brackish microbiome.
Hugerth LW, Larsson J, Alneberg J, ..., Pinhassi J, Andersson AF
Genome Biol. 16 (-) 279 [2015-12-14; online 2015-12-14]
High levels of WNT-5A in human glioma correlate with increased presence of tumor-associated microglia/monocytes.
Dijksterhuis JP, Arthofer E, Marinescu VD, ..., Mulder J, Schulte G
Exp. Cell Res. 339 (2) 280-288 [2015-12-10; online 2015-10-25]
Pleiotrophin promotes vascular abnormalization in gliomas and correlates with poor survival in patients with astrocytomas.
Zhang L, Kundu S, Feenstra T, ..., Dieterich LC, Dimberg A
Sci Signal 8 (406) ra125 [2015-12-08; online 2015-12-08]
Tumor-Induced Local and Systemic Impact on Blood Vessel Function.
Cedervall J, Dimberg A, Olsson AK
Mediators Inflamm. 2015 (-) 418290 [2015-12-07; online 2015-12-07]
Bioinformatics Mining and Modeling Methods for the Identification of Disease Mechanisms in Neurodegenerative Disorders.
Hofmann-Apitius M, Ball G, Gebel S, ..., Tegnér J, Canard L
Int J Mol Sci 16 (12) 29179-29206 [2015-12-07; online 2015-12-07]
Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation.
Soler Artigas M, Wain LV, Miller S, ..., Hall IP, Tobin MD
Nat Commun 6 (-) 8658 [2015-12-04; online 2015-12-04]
Multipotent versus differentiated cell fate selection in the developing Drosophila airways.
Matsuda R, Hosono C, Samakovlis C, Saigo K
Elife 4 (-) - [2015-12-02; online 2015-12-02]
Editorial: Microbial Responses to Environmental Changes.
Logue JB, Findlay SE, Comte J
Front Microbiol 6 (-) 1364 [2015-12-02; online 2015-12-02]
cgmisc: enhanced genome-wide association analyses and visualization.
Kierczak M, Jabłońska J, Forsberg SK, ..., Carlborg Ö, Lindblad-Toh K
Bioinformatics 31 (23) 3830-3831 [2015-12-01; online 2015-08-06]
Stratification of Hepatocellular Carcinoma Patients Based on Acetate Utilization.
Björnson E, Mukhopadhyay B, Asplund A, ..., Nielsen J, Mardinoglu A
Cell Reports 13 (9) 2014-2026 [2015-12-01; online 2015-11-19]
Rapid and Efficient Conversion of (11) CO2 to (11) CO through Silacarboxylic Acids: Applications in Pd-Mediated Carbonylations.
Nordeman P, Friis SD, Andersen TL, ..., Skrydstrup T, Antoni G
Chemistry 21 (49) 17601-17604 [2015-12-01; online 2015-10-23]
Protein profiling reveals consequences of lifestyle choices on predicted biological aging.
Enroth S, Enroth SB, Johansson Å, Gyllensten U
Sci Rep 5 (-) 17282 [2015-12-01; online 2015-12-01]
Multi-level omics analysis in a murine model of dystrophin loss and therapeutic restoration.
Roberts TC, Johansson HJ, McClorey G, ..., El Andaloussi S, Wood MJ
Hum. Mol. Genet. 24 (23) 6756-6768 [2015-12-01; online 2015-09-18]
Highly Sensitive FRET-FCS Detects Amyloid β-Peptide Oligomers in Solution at Physiological Concentrations.
Wennmalm S, Chmyrov V, Widengren J, Tjernberg L
Anal. Chem. 87 (23) 11700-11705 [2015-12-01; online 2015-11-10]
Gene-based meta-analysis of genome-wide association studies implicates new loci involved in obesity.
Hägg S, Ganna A, Van Der Laan SW, ..., Pawitan Y, Ingelsson E
Hum. Mol. Genet. 24 (23) 6849-6860 [2015-12-01; online 2015-09-16]
Cyclophilin D, a target for counteracting skeletal muscle dysfunction in mitochondrial myopathy.
Gineste C, Hernandez A, Ivarsson N, ..., Wredenberg A, Westerblad H
Hum. Mol. Genet. 24 (23) 6580-6587 [2015-12-01; online 2015-09-14]
ARResT/AssignSubsets: a novel application for robust subclassification of chronic lymphocytic leukemia based on B cell receptor IG stereotypy.
Bystry V, Agathangelidis A, Bikos V, ..., Darzentas N, European Research Initiative on CLL
Bioinformatics 31 (23) 3844-3846 [2015-12-01; online 2015-08-06]
A genome-wide IR-induced RAD51 foci RNAi screen identifies CDC73 involved in chromatin remodeling for DNA repair.
Herr P, Lundin C, Evers B, ..., Sonnhammer E, Helleday T
Cell Discov 1 (-) 15034 [2015-12-01; online 2015-12-01]
p11 regulates the surface localization of mGluR5.
Lee KW, Westin L, Kim J, ..., Kim Y, Greengard P
Mol. Psychiatry 20 (12) 1485 [2015-12-00; online 2015-11-19]
The body mass index (BMI) is significantly correlated with levels of cytokines and chemokines in cerebrospinal fluid.
Larsson A, Carlsson L, Lind AL, ..., Kamali-Moghaddam M, Thulin M
Cytokine 76 (2) 514-518 [2015-12-00; online 2015-07-15]
The Constrained Maximal Expression Level Owing to Haploidy Shapes Gene Content on the Mammalian X Chromosome.
Hurst LD, Ghanbarian AT, Forrest AR, FANTOM consortium , Huminiecki L
PLoS Biol. 13 (12) e1002315 [2015-12-00; online 2015-12-18]
Tamoxifen Inhibits TGF-β-Mediated Activation of Myofibroblasts by Blocking Non-Smad Signaling Through ERK1/2.
Carthy JM, Sundqvist A, Heldin A, ..., Heldin CH, Moustakas A
J. Cell. Physiol. 230 (12) 3084-3092 [2015-12-00; online 2015-06-23]
ISDN2014_0322: REMOVED: Identification of novel genetic causes of Rett syndrome‐like phenotypes by whole exome sequencing
Lopes F, Barbosa M, Temudo T, ..., Ulf Gyllensten , Maciel P
Intl J of Devlp Neuroscience 47 (Part_A) 99-99 [2015-12-00; online 2015-11-05]
Gout and its comorbidities in the total population of Stockholm.
Wändell P, Carlsson AC, Ljunggren G
Prev Med 81 (-) 387-391 [2015-12-00; online 2015-10-21]
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.
Gaulton KJ, Ferreira T, Lee Y, ..., Morris AP, DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium
Nat. Genet. 47 (12) 1415-1425 [2015-12-00; online 2015-11-09]
Development of autoantibodies against muscle-specific FHL1 in severe inflammatory myopathies.
Albrecht I, Wick C, Hallgren Å, ..., Kämpe O, Lundberg IE
J. Clin. Invest. 125 (12) 4612-4624 [2015-12-00; online 2015-11-09]
Daily self-sampling for high-risk human papillomavirus (HR-HPV) testing.
Sanner K, Wikström I, Gustavsson I, ..., Gyllensten U, Olovsson M
J. Clin. Virol. 73 (-) 1-7 [2015-12-00; online 2015-10-08]
Characterization of the honeybee AmNaV1 channel and tools to assess the toxicity of insecticides
Gosselin-Badaroudine P, Moreau A, Delemotte L, ..., Klein ML, Chahine M
Sci Rep 5 (1) - [2015-12-00; online 2015-07-23]
Lucie Delemotte SciLifeLab Fellow
Bacterial diversity along a 2600 km river continuum.
Savio D, Sinclair L, Ijaz UZ, ..., Farnleitner AH, Eiler A
Environ. Microbiol. 17 (12) 4994-5007 [2015-12-00; online 2015-06-11]
Alteration by p11 of mGluR5 localization regulates depression-like behaviors.
Lee KW, Westin L, Kim J, ..., Kim Y, Greengard P
Mol. Psychiatry 20 (12) 1546-1556 [2015-12-00; online 2015-09-15]
Adaptation to acetaminophen exposure elicits major changes in expression and distribution of the hepatic proteome.
Eakins R, Walsh J, Randle L, ..., Goldring CE, Park BK
Sci Rep 5 (-) 16423 [2015-11-26; online 2015-11-26]
Single-cell screening of photosynthetic growth and lactate production by cyanobacteria.
Hammar P, Angermayr SA, Sjostrom SL, ..., Hudson EP, Joensson HN
Biotechnol Biofuels 8 (1) 193 [2015-11-25; online 2015-11-25]
Machine Learning Based Classification of Microsatellite Variation: An Effective Approach for Phylogeographic Characterization of Olive Populations.
Torkzaban B, Kayvanjoo AH, Ardalan A, ..., Ebrahimi M, Hosseini-Mazinani M
PLoS ONE 10 (11) e0143465 [2015-11-24; online 2015-11-24]
Amelanism in the corn snake is associated with the insertion of an LTR-retrotransposon in the OCA2 gene.
Saenko SV, Lamichhaney S, Martinez Barrio A, ..., Andersson L, Milinkovitch MC
Sci Rep 5 (-) 17118 [2015-11-24; online 2015-11-24]
Functional Characterization of Germline Mutations in PDGFB and PDGFRB in Primary Familial Brain Calcification.
Vanlandewijck M, Lebouvier T, Andaloussi Mäe M, ..., Keller A, Betsholtz C
PLoS ONE 10 (11) e0143407 [2015-11-23; online 2015-11-23]
Kinetic Studies to Elucidate Impaired Metabolism of Triglyceride-rich Lipoproteins in Humans.
Adiels M, Mardinoglu A, Taskinen MR, Borén J
Front. Physiol. 6 (-) 342 [2015-11-20; online 2015-11-20]
RNA sequencing uncovers antisense RNAs and novel small RNAs in Streptococcus pyogenes.
Le Rhun A, Beer YY, Reimegård J, Chylinski K, Charpentier E
RNA Biol 13 (2) 177-195 [2015-11-19; online 2015-11-19]
Jagged 1 Rescues the Duchenne Muscular Dystrophy Phenotype.
Vieira NM, Elvers I, Alexander MS, ..., Kunkel LM, Zatz M
Cell 163 (5) 1204-1213 [2015-11-19; online 2015-11-12]
Single cell analysis of cancer cells using an improved RT-MLPA method has potential for cancer diagnosis and monitoring.
Kvastad L, Werne Solnestam B, Johansson E, ..., Latta D, Lundeberg J
Sci Rep 5 (-) 16519 [2015-11-12; online 2015-11-12]
NPM1 histone chaperone is upregulated in glioblastoma to promote cell survival and maintain nucleolar shape.
Holmberg Olausson K, Elsir T, Moazemi Goudarzi K, Nistér M, Lindström MS
Sci Rep 5 (-) 16495 [2015-11-12; online 2015-11-12]
The 2015 super-resolution microscopy roadmap
Hell SW, Sahl SJ, Bates M, ..., Diaspro A, Cordes T
J. Phys. D: Appl. Phys. 48 (44) 443001 [2015-11-11; online 2015-10-15]
Ilaria Testa SciLifeLab Fellow
Immunocapture strategies in translational proteomics.
Fredolini C, Byström S, Pin E, ..., Nilsson P, Schwenk JM
Expert Rev Proteomics 13 (1) 83-98 [2015-11-11; online 2015-11-11]
Molecular signatures of plastic phenotypes in two eusocial insect species with simple societies.
Patalano S, Vlasova A, Wyatt C, ..., Reik W, Sumner S
Proc. Natl. Acad. Sci. U.S.A. 112 (45) 13970-13975 [2015-11-10; online 2015-10-19]
Acute MUS81 depletion leads to replication fork slowing and a constitutive DNA damage response.
Xing M, Wang X, Palmai-Pallag T, ..., Hickson ID, Ying S
Oncotarget 6 (35) 37638-37646 [2015-11-10; online 2015-09-29]
Affiliated researcher
An 8 minute colorimetric paper-based reverse phase vertical flow serum microarray for screening of hyper IgE syndrome.
Reuterswärd P, Gantelius J, Andersson Svahn H
Analyst 140 (21) 7327-7334 [2015-11-07; online 2015-09-15]
Development of Phage-Based Antibody Fragment Reagents for Affinity Enrichment of Bacterial Immunoglobulin G Binding Proteins.
Säll A, Sjöholm K, Waldemarson S, ..., Persson H, Malmström J
J. Proteome Res. 14 (11) 4704-4713 [2015-11-06; online 2015-10-27]
Intra-mitochondrial Methylation Deficiency Due to Mutations in SLC25A26.
Kishita Y, Pajak A, Bolar NA, ..., Okazaki Y, Wedell A
Am. J. Hum. Genet. 97 (5) 761-768 [2015-11-05; online 2015-10-29]
Castration radiosensitizes prostate cancer tissue by impairing DNA double-strand break repair.
Tarish FL, Schultz N, Tanoglidi A, ..., Granfors T, Helleday T
Sci Transl Med 7 (312) 312re11 [2015-11-04; online 2015-11-06]
NSMCE2 suppresses cancer and aging in mice independently of its SUMO ligase activity.
Jacome A, Gutierrez-Martinez P, Schiavoni F, ..., Blasco MA, Fernandez-Capetillo O
EMBO J. 34 (21) 2604-2619 [2015-11-03; online 2015-10-06]
Topological Evaluation of Methods for Reconstruction of Genetic Regulatory Networks
Olczak J, Kiani NA, Zenil H, Tegner J
- - (-) 468-473 [2015-11-00; online 2015-11-00]
The ketogenic diet compensates for AGC1 deficiency and improves myelination.
Dahlin M, Martin DA, Hedlund Z, ..., von Döbeln U, Wedell A
Epilepsia 56 (11) e176-e181 [2015-11-00; online 2015-09-24]
The Human Endometrium-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling.
Zieba A, Sjöstedt E, Olovsson M, ..., Uhlen M, Ponten F
OMICS 19 (11) 659-668 [2015-11-00; online 2015-10-21]
Slow degradation in phagocytic astrocytes can be enhanced by lysosomal acidification.
Lööv C, Mitchell CH, Simonsson M, Erlandsson A
Glia 63 (11) 1997-2009 [2015-11-00; online 2015-06-12]
Single-cell genomics of a rare environmental alphaproteobacterium provides unique insights into Rickettsiaceae evolution.
Martijn J, Schulz F, Zaremba-Niedzwiedzka K, ..., Guy L, Ettema TJ
ISME J 9 (11) 2373-2385 [2015-11-00; online 2015-04-07]
Single-Molecule Sequencing Reveals Estrogen-Regulated Clinically Relevant lncRNAs in Breast Cancer.
Jonsson P, Coarfa C, Mesmar F, ..., Gunaratne PH, Williams C
Mol. Endocrinol. 29 (11) 1634-1645 [2015-11-00; online 2015-10-01]
Risks and benefits of sex-mismatched hematopoietic cell transplantation differ according to conditioning strategy.
Nakasone H, Remberger M, Tian L, ..., Miklos DB, Meyer E
Haematologica 100 (11) 1477-1485 [2015-11-00; online 2015-08-06]
Rescue of primary ubiquinone deficiency due to a novel COQ7 defect using 2,4-dihydroxybensoic acid.
Freyer C, Stranneheim H, Naess K, ..., Wredenberg A, Wedell A
J. Med. Genet. 52 (11) 779-783 [2015-11-00; online 2015-06-17]
Proteomic Profiling of Detergent Resistant Membranes (Lipid Rafts) of Prostasomes.
Dubois L, Ronquist KK, Ek B, Ronquist G, Larsson A
Mol. Cell Proteomics 14 (11) 3015-3022 [2015-11-00; online 2015-08-13]
Population genetic differentiation of height and body mass index across Europe.
Robinson MR, Hemani G, Medina-Gomez C, ..., Yang J, Visscher PM
Nat. Genet. 47 (11) 1357-1362 [2015-11-00; online 2015-09-14]
Mutation in CEP63 co-segregating with developmental dyslexia in a Swedish family.
Einarsdottir E, Svensson I, Darki F, ..., Kere J, Matsson H
Hum. Genet. 134 (11-12) 1239-1248 [2015-11-00; online 2015-09-23]
Larger aggregates of mutant seipin in Celia's Encephalopathy, a new protein misfolding neurodegenerative disease.
Ruiz-Riquelme A, Sánchez-Iglesias S, Rábano A, ..., Araújo-Vilar D, Requena JR
Neurobiol. Dis. 83 (-) 44-53 [2015-11-00; online 2015-08-15]
Integrating Sequence Evolution into Probabilistic Orthology Analysis.
Ullah I, Sjöstrand J, Andersson P, Sennblad B, Lagergren J
Syst. Biol. 64 (6) 969-982 [2015-11-00; online 2015-06-30]
In situ forming interpenetrating hydrogels of hyaluronic acid hybridized with iron oxide nanoparticles.
Kheirabadi M, Shi L, Bagheri R, ..., Hilborn J, Ossipov DA
Biomater Sci 3 (11) 1466-1474 [2015-11-00; online 2015-08-08]
Impact of sludge deposition on biodiversity.
Manzetti S, van der Spoel D
Ecotoxicology 24 (9) 1799-1814 [2015-11-00; online 2015-08-30]
HaloPlex Targeted Resequencing for Mutation Detection in Clinical Formalin-Fixed, Paraffin-Embedded Tumor Samples.
Moens LN, Falk-Sörqvist E, Ljungström V, ..., Nilsson M, Botling J
J Mol Diagn 17 (6) 729-739 [2015-11-00; online 2015-09-03]
Genome-Wide Association Study of Golden Retrievers Identifies Germ-Line Risk Factors Predisposing to Mast Cell Tumours.
Arendt ML, Melin M, Tonomura N, ..., Starkey M, Lindblad-Toh K
PLoS Genet 11 (11) e1005647 [2015-11-00; online 2015-11-20]
Exome sequencing of lymphomas from three dog breeds reveals somatic mutation patterns reflecting genetic background.
Elvers I, Turner-Maier J, Swofford R, ..., Lindblad-Toh K, Alföldi J
Genome Res 25 (11) 1634-1645 [2015-11-00; online 2015-09-16]
Early Exposure to Dogs and Farm Animals and the Risk of Childhood Asthma.
Fall T, Lundholm C, Örtqvist AK, ..., Ingelsson E, Almqvist C
JAMA Pediatr 169 (11) e153219 [2015-11-00; online 2015-11-02]
Assessing the consistency of public human tissue RNA-seq data sets.
Danielsson F, James T, Gomez-Cabrero D, Huss M
Brief. Bioinformatics 16 (6) 941-949 [2015-11-00; online 2015-03-30]
Identification of proteins highly expressed in uterine fluid from mice with hydrometra.
Antonson P, Nalvarte I, Varshney M, ..., Gustafsson JÅ, Dahlman-Wright K
Biochem. Biophys. Res. Commun. 466 (4) 650-655 [2015-10-30; online 2015-09-21]
Paving the way to targeting HECT ubiquitin ligases.
Zinzalla G
Future Med Chem 7 (16) 2107-2111 [2015-10-29; online 2015-10-29]
Crosstalk between Hippo and TGFβ: Subcellular Localization of YAP/TAZ/Smad Complexes.
Grannas K, Arngården L, Lönn P, ..., Zieba A, Söderberg O
J. Mol. Biol. 427 (21) 3407-3415 [2015-10-23; online 2015-05-01]
Affiliated researcher
The effect of N-methylation of amino acids (Ac-X-OMe) on solubility and conformation: a DFT study.
Md Abdur Rauf S, Arvidsson PI, Albericio F, ..., Kruger HG, Honarparvar B
Org. Biomol. Chem. 13 (39) 9993-10006 [2015-10-21; online 2015-08-21]
Genetic Polymorphisms in Vitamin D Metabolism and Signaling Genes and Risk of Breast Cancer: A Nested Case-Control Study.
Clendenen TV, Ge W, Koenig KL, ..., Sund M, Zeleniuch-Jacquotte A
PLoS ONE 10 (10) e0140478 [2015-10-21; online 2015-10-21]
Structure-activity relationships for lipoprotein lipase agonists that lower plasma triglycerides in vivo.
Caraballo R, Larsson M, Nilsson SK, ..., Enquist PA, Elofsson M
Eur J Med Chem 103 (-) 191-209 [2015-10-20; online 2015-09-02]
Induction of USP17 by combining BET and HDAC inhibitors in breast cancer cells.
Borbely G, Haldosen LA, Dahlman-Wright K, Zhao C
Oncotarget 6 (32) 33623-33635 [2015-10-20; online 2015-09-18]
Controlled Lateral Positioning of Microparticles Inside Droplets Using Acoustophoresis.
Fornell A, Nilsson J, Jonsson L, ..., Joensson HN, Tenje M
Anal. Chem. 87 (20) 10521-10526 [2015-10-20; online 2015-10-09]
Structural Basis for Oxygen Activation at a Heterodinuclear Manganese/Iron Cofactor.
Griese JJ, Kositzki R, Schrapers P, ..., Haumann M, Högbom M
J Biol Chem 290 (42) 25254-25272 [2015-10-16; online 2015-08-31]
Genetic and nutrient modulation of acetyl-CoA levels in Synechocystis for n-butanol production.
Anfelt J, Kaczmarzyk D, Shabestary K, ..., Uhlén M, Hudson EP
Microb Cell Fact 14 (1) 167 [2015-10-16; online 2015-10-16]
Domestication Effects on Stress Induced Steroid Secretion and Adrenal Gene Expression in Chickens.
Fallahsharoudi A, de Kock N, Johnsson M, ..., Wright D, Jensen P
Sci Rep 5 (-) 15345 [2015-10-16; online 2015-10-16]
Role of the AMP kinase in cytokine-induced human EndoC-βH1 cell death.
Fred RG, Kappe C, Ameur A, ..., Scharfmann R, Welsh N
Mol. Cell. Endocrinol. 414 (-) 53-63 [2015-10-15; online 2015-07-26]
Poisoning Cancer Cells with Oxidized Nucleosides.
Helleday T
N. Engl. J. Med. 373 (16) 1570-1571 [2015-10-15; online 2015-10-16]
A straightforward approach for gated STED-FCS to investigate lipid membrane dynamics.
Clausen MP, Sezgin E, Bernardino de la Serna J, ..., Lagerholm BC, Eggeling C
Methods 88 (-) 67-75 [2015-10-15; online 2015-06-27]
Erdinc Sezgin SciLifeLab Fellow
Mutation in NRAS in familial Noonan syndrome--case report and review of the literature.
Ekvall S, Wilbe M, Dahlgren J, ..., Annerén G, Bondeson ML
BMC Med. Genet. 16 (-) 95 [2015-10-14; online 2015-10-14]
The folate-coupled enzyme MTHFD2 is a nuclear protein and promotes cell proliferation.
Gustafsson Sheppard N, Jarl L, Mahadessian D, ..., Jain M, Nilsson R
Sci Rep 5 (-) 15029 [2015-10-13; online 2015-10-13]
Thousands of RAD-seq Loci Fully Resolve the Phylogeny of the Highly Disjunct Arctic-Alpine Genus Diapensia (Diapensiaceae).
Hou Y, Nowak MD, Mirré V, ..., Brochmann C, Popp M
PLoS ONE 10 (10) e0140175 [2015-10-08; online 2015-10-08]
The alternative splicing factor Nova2 regulates vascular development and lumen formation.
Giampietro C, Deflorian G, Gallo S, ..., Dejana E, Ghigna C
Nat Commun 6 (-) 8479 [2015-10-08; online 2015-10-08]
Extensive weight loss reveals distinct gene expression changes in human subcutaneous and visceral adipose tissue.
Mardinoglu A, Heiker JT, Gärtner D, ..., Nielsen J, Blüher M
Sci Rep 5 (1) 14841 [2015-10-05; online 2015-10-05]
Gene-pseudogene evolution: a probabilistic approach.
Mahmudi O, Sennblad B, Arvestad L, Nowick K, Lagergren J
BMC Genomics 16 Suppl 10 (Suppl 10) S12 [2015-10-02; online 2015-10-02]
Expanding the Catalytic Triad in Epoxide Hydrolases and Related Enzymes.
Amrein BA, Bauer P, Duarte F, ..., Widersten M, Kamerlin SC
ACS Catal 5 (10) 5702-5713 [2015-10-02; online 2015-08-17]
Transcriptome Sequencing Reveals PCAT5 as a Novel ERG-Regulated Long Noncoding RNA in Prostate Cancer.
Ylipää A, Kivinummi K, Kohvakka A, ..., Visakorpi T, Nykter M
Cancer Res. 75 (19) 4026-4031 [2015-10-01; online 2015-08-17]
DDLS Fellow Kimmo Kartasalo
Timeless Interacts with PARP-1 to Promote Homologous Recombination Repair.
Xie S, Mortusewicz O, Ma HT, ..., Helleday T, Qian C
Mol. Cell 60 (1) 163-176 [2015-10-01; online 2015-09-03]
Spatiotemporal Heterogeneity Characterizes the Genetic Landscape of Pheochromocytoma and Defines Early Events in Tumorigenesis.
Crona J, Backman S, Maharjan R, ..., Hellman P, Björklund P
Clin. Cancer Res. 21 (19) 4451-4460 [2015-10-01; online 2015-05-19]
Neuropeptide Y family receptors Y1 and Y2 from sea lamprey, Petromyzon marinus.
Xu B, Lagman D, Sundström G, Larhammar D
Gen. Comp. Endocrinol. 222 (-) 106-115 [2015-10-01; online 2015-08-06]
Homozygous loss-of-function variants in European cosmopolitan and isolate populations.
Kaiser VB, Svinti V, Prendergast JG, ..., Semple CA, Wilson JF
Hum. Mol. Genet. 24 (19) 5464-5474 [2015-10-01; online 2015-07-14]
Transcriptome Profiling Reveals Degree of Variability in Induced Pluripotent Stem Cell Lines: Impact for Human Disease Modeling.
Schuster J, Halvardson J, Pilar Lorenzo L, ..., Feuk L, Dahl N
Cell Reprogram 17 (5) 327-337 [2015-10-00; online 2015-09-08]
The effects of age and gender on plasma levels of 63 cytokines.
Larsson A, Carlsson L, Gordh T, ..., Thulin M, Kamali-Moghaddam M
J. Immunol. Methods 425 (-) 58-61 [2015-10-00; online 2015-06-14]
The cyanobacterium Mastigocladus fulfills the nitrogen demand of a terrestrial hot spring microbial mat.
Estrella Alcamán M, Fernandez C, Delgado A, Bergman B, Díez B
ISME J 9 (10) 2290-2303 [2015-10-00; online 2015-07-31]
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J. Cell Biol. 210 (2) 319-332 [2015-07-20; online 2015-07-13]
Mitochondrial ribosome assembly in health and disease
De Silva D, Tu YT, Amunts A, Fontanesi F, Barrientos A
Cell Cycle 14 (14) 2226-2250 [2015-07-18; online 2015-06-00]
Alexey Amunts SciLifeLab Fellow
Epigenome data release: a participant-centered approach to privacy protection.
Dyke SO, Cheung WA, Joly Y, ..., Walter J, Pastinen T
Genome Biol. 16 (1) 142 [2015-07-17; online 2015-07-17]
SAXS-Guided Metadynamics.
Kimanius D, Pettersson I, Schluckebier G, Lindahl E, Andersson M
J Chem Theory Comput 11 (7) 3491-3498 [2015-07-14; online 2015-11-18]
Properties of Organic Liquids when Simulated with Long-Range Lennard-Jones Interactions.
Fischer NM, van Maaren PJ, Ditz JC, Yildirim A, van der Spoel D
J Chem Theory Comput 11 (7) 2938-2944 [2015-07-14; online 2015-06-02]
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Nat Commun 6 (-) 7688 [2015-07-09; online 2015-07-09]
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BMC Genomics 16 (1) 499 [2015-07-04; online 2015-07-04]
Discovery of GPCR Ligands by Molecular Docking Screening: Novel Opportunities Provided by Crystal Structures.
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A Synergistic Interaction between Chk1- and MK2 Inhibitors in KRAS-Mutant Cancer.
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Cell 162 (1) 146-159 [2015-07-02; online 2015-07-04]
The TOPCONS web server for consensus prediction of membrane protein topology and signal peptides.
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Replication of Genetic Polymorphisms Reported to Be Associated with Taxane-Related Sensory Neuropathy in Patients with Early Breast Cancer Treated with Paclitaxel--letter.
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Neutrophil Extracellular Traps Accumulate in Peripheral Blood Vessels and Compromise Organ Function in Tumor-Bearing Animals.
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Critical Role of Histone Turnover in Neuronal Transcription and Plasticity.
Maze I, Wenderski W, Noh KM, ..., Molina H, Allis CD
Neuron 87 (1) 77-94 [2015-07-01; online 2015-07-04]
SciLifeLab Fellow Simon Elsässer
Using Genetic Variants to Assess the Relationship Between Circulating Lipids and Type 2 Diabetes.
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Diabetes 64 (7) 2676-2684 [2015-07-00; online 2015-05-06]
Toward Rare Blood Cell Preservation for RNA Sequencing.
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The Nuclear PolyA-Binding Protein Nab2p Is Essential for mRNA Production
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Cell Reports 12 (1) 128-139 [2015-07-00; online 2015-07-00]
SciLifeLab Fellow Vicent Pelechano
Quality of life in patients with venous thromboembolism and atrial fibrillation treated with coumarin anticoagulants.
Marvig CL, Verhoef TI, de Boer A, ..., Maitland-van der Zee AH, EU-PACT consortium
Thromb. Res. 136 (1) 69-75 [2015-07-00; online 2015-04-25]
Polymorphisms in DCDC2 and S100B associate with developmental dyslexia.
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Neuroproteomics tools in clinical practice.
Shevchenko G, Konzer A, Musunuri S, Bergquist J
Biochim. Biophys. Acta 1854 (7) 705-717 [2015-07-00; online 2015-02-10]
Metabolite profiling of microfluidic cell culture conditions for droplet based screening.
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Biomicrofluidics 9 (4) 044128 [2015-07-00; online 2015-08-31]
Insertion of exogenous epitopes in the E3-19K of oncolytic adenoviruses to enhance TAP-independent presentation and immunogenicity.
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High-throughput gene targeting and phenotyping in zebrafish using CRISPR/Cas9.
Varshney GK, Pei W, LaFave MC, ..., Ledin J, Burgess SM
Genome Res 25 (7) 1030-1042 [2015-07-00; online 2015-06-05]
Endothelial cell spheroids as a versatile tool to study angiogenesis in vitro.
Heiss M, Hellström M, Kalén M, ..., Augustin HG, Korff T
FASEB J. 29 (7) 3076-3084 [2015-07-00; online 2015-04-09]
Disentangling seasonal bacterioplankton population dynamics by high-frequency sampling.
Lindh MV, Sjöstedt J, Andersson AF, ..., Legrand C, Pinhassi J
Environ. Microbiol. 17 (7) 2459-2476 [2015-07-00; online 2015-01-27]
Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation.
Horikoshi M, Mӓgi R, van de Bunt M, ..., Morris AP, ENGAGE Consortium
PLoS Genet 11 (7) e1005230 [2015-07-00; online 2015-07-01]
BBMRI-ERIC as a resource for pharmaceutical and life science industries: the development of biobank-based Expert Centres.
van Ommen GJ, Törnwall O, Bréchot C, ..., Litton JE, Zatloukal K
Eur. J. Hum. Genet. 23 (7) 893-900 [2015-07-00; online 2014-11-19]
Structural Basis for the Specificity of Human NUDT16 and Its Regulation by Inosine Monophosphate.
Trésaugues L, Lundbäck T, Welin M, ..., Gräslund S, Nordlund P
PLoS ONE 10 (6) e0131507 [2015-06-29; online 2015-06-29]
The human cardiac and skeletal muscle proteomes defined by transcriptomics and antibody-based profiling.
Lindskog C, Linné J, Fagerberg L, ..., Pontén F, Uhlén M
BMC Genomics 16 (1) 475 [2015-06-25; online 2015-06-25]
Transcriptional modulator ZBED6 affects cell cycle and growth of human colorectal cancer cells.
Akhtar Ali M, Younis S, Wallerman O, ..., Andersson L, Sjöblom T
Proc. Natl. Acad. Sci. U.S.A. 112 (25) 7743-7748 [2015-06-23; online 2015-06-08]
Linked genetic variants on chromosome 10 control ear morphology and body mass among dog breeds.
Webster MT, Kamgari N, Perloski M, ..., Pielberg G, Lindblad-Toh K
BMC Genomics 16 (1) 474 [2015-06-23; online 2015-06-23]
Transforming growth factor β and bone morphogenetic protein actions in brain tumors.
Caja L, Bellomo C, Moustakas A
FEBS Lett. 589 (14) 1588-1597 [2015-06-22; online 2015-05-06]
Force Field Benchmark of Organic Liquids. 2. Gibbs Energy of Solvation.
Zhang J, Tuguldur B, van der Spoel D
J Chem Inf Model 55 (6) 1192-1201 [2015-06-22; online 2015-06-03]
Transglutaminase 4 as a prostate autoantigen in male subfertility.
Landegren N, Sharon D, Shum AK, ..., Snyder M, Kämpe O
Sci Transl Med 7 (292) 292ra101 [2015-06-17; online 2015-06-19]
Elevated Serum GAD65 and GAD65-GADA Immune Complexes in Stiff Person Syndrome.
Gu Urban GJ, Friedman M, Ren P, ..., Landegren U, Kamali-Moghaddam M
Sci Rep 5 (-) 11196 [2015-06-16; online 2015-06-16]
Mobility-based prediction of hydration structures of protein surfaces.
Jeszenői N, Horváth I, Bálint M, van der Spoel D, Hetényi C
Bioinformatics 31 (12) 1959-1965 [2015-06-15; online 2015-02-13]
Defining the Human Brain Proteome Using Transcriptomics and Antibody-Based Profiling with a Focus on the Cerebral Cortex.
Sjöstedt E, Fagerberg L, Hallström BM, ..., Uhlén M, Mulder J
PLoS ONE 10 (6) e0130028 [2015-06-15; online 2015-06-15]
Proximity-dependent initiation of hybridization chain reaction.
Koos B, Cane G, Grannas K, ..., Kamali-Moghaddam M, Söderberg O
Nat Commun 6 (-) 7294 [2015-06-12; online 2015-06-12]
Histone H3.3 is required for endogenous retroviral element silencing in embryonic stem cells.
Elsässer SJ, Noh KM, Diaz N, Allis CD, Banaszynski LA
Nature 522 (7555) 240-244 [2015-06-11; online 2015-05-04]
Phasing of single DNA molecules by massively parallel barcoding.
Borgström E, Redin D, Lundin S, ..., Andersson AF, Ahmadian A
Nat Commun 6 (-) 7173 [2015-06-09; online 2015-06-09]
Next-generation pathology--surveillance of tumor microecology.
Koos B, Kamali-Moghaddam M, David L, ..., Wählby C, Söderberg O
J. Mol. Biol. 427 (11) 2013-2022 [2015-06-05; online 2015-02-26]
Affiliated researcher
Excessive antigen reactivity may underlie the clinical aggressiveness of chronic lymphocytic leukemia stereotyped subset #8.
Gounari M, Ntoufa S, Apollonio B, ..., Stamatopoulos K, Ghia P
Blood 125 (23) 3580-3587 [2015-06-04; online 2015-04-21]
A quantitative assessment of the Hadoop framework for analyzing massively parallel DNA sequencing data.
Siretskiy A, Sundqvist T, Voznesenskiy M, Spjuth O
Gigascience 4 (-) 26 [2015-06-04; online 2015-06-04]
Single-cell polyadenylation site mapping reveals 3' isoform choice variability.
Velten L, Anders S, Pekowska A, ..., Pelechano V, Steinmetz LM
Mol Syst Biol 11 (6) 812 [2015-06-03; online 2015-06-03]
SciLifeLab Fellow Vicent Pelechano
Processing of protein ADP-ribosylation by Nudix hydrolases.
Palazzo L, Thomas B, Jemth AS, ..., Helleday T, Ahel I
Biochem. J. 468 (2) 293-301 [2015-06-01; online 2015-03-20]
Functional loss of IκBε leads to NF-κB deregulation in aggressive chronic lymphocytic leukemia.
Mansouri L, Sutton LA, Ljungström V, ..., Nilsson M, Rosenquist R
J. Exp. Med. 212 (6) 833-843 [2015-06-01; online 2015-05-18]
Transforming Growth Factor β Signaling in Colorectal Cancer Cells With Microsatellite Instability Despite Biallelic Mutations in TGFBR2.
de Miranda NF, van Dinther M, van den Akker BE, ..., ten Dijke P, Morreau H
Gastroenterology 148 (7) 1427-37.e8 [2015-06-00; online 2015-02-28]
The impact of low-frequency and rare variants on lipid levels.
Surakka I, Horikoshi M, Mägi R, ..., Ripatti S, ENGAGE Consortium
Nat. Genet. 47 (6) 589-597 [2015-06-00; online 2015-05-11]
THU0481 Discovery of Potential Serum Biomarkers in Osteoarthritis Using Protein Arrays
Lourido L, Ayoglu B, Henjes F, ..., Nilsson P, Blanco FJ
Ann Rheum Dis 74 (-) 373-374 [2015-06-00; online 2015-06-00]
Significance of archaeal nitrification in hypoxic waters of the Baltic Sea.
Berg C, Vandieken V, Thamdrup B, Jürgens K
ISME J 9 (6) 1319-1332 [2015-06-00; online 2014-11-25]
OP0271 Analysis of the Autoantibody Repertoire in Idiopathic Inflammatory Myopathies Using Antigen Bead Array
Notarnicola A, Mattsson C, Idborg H, ..., Nilsson P, Lundberg IE
Ann Rheum Dis 74 (-) 174 [2015-06-00; online 2015-06-00]
Multiple Changes of Gene Expression and Function Reveal Genomic and Phenotypic Complexity in SLE-like Disease.
Wilbe M, Kozyrev SV, Farias FH, ..., Hansson-Hamlin H, Lindblad-Toh K
PLoS Genet 11 (6) e1005248 [2015-06-00; online 2015-06-09]
Molecular evidence for antigen drive in the natural history of mantle cell lymphoma.
Xochelli A, Sutton LA, Agathangelidis A, ..., Belessi C, Stamatopoulos K
Am. J. Pathol. 185 (6) 1740-1748 [2015-06-00; online 2015-04-02]
Microbial metagenomics in the Baltic Sea: Recent advancements and prospects for environmental monitoring.
Ininbergs K, Bergman B, Larsson J, Ekman M
Ambio 44 Suppl 3 (Suppl 3) 439-450 [2015-06-00; online 2015-05-30]
MATHEMATICAL MODELING OF BEHÇET'S DISEASE: A DYNAMICAL SYSTEMS APPROACH
ERDEM C, BOZKURT Y, ERMAN B, GÜL A, DEMIR A
J. Biol. Syst. 23 (02) 231-257 [2015-06-00; online 2015-05-28]
Cemal Erdem DDLS Fellow
Loss of ASRGL1 expression is an independent biomarker for disease-specific survival in endometrioid endometrial carcinoma.
Edqvist PH, Huvila J, Forsström B, ..., Pontén F, Auranen A
Gynecol. Oncol. 137 (3) 529-537 [2015-06-00; online 2015-04-07]
Human adaptation to arsenic-rich environments.
Schlebusch CM, Gattepaille LM, Engström K, ..., Jakobsson M, Broberg K
Mol. Biol. Evol. 32 (6) 1544-1555 [2015-06-00; online 2015-03-03]
Exome sequencing of contralateral breast cancer identifies metastatic disease.
Klevebring D, Lindberg J, Rockberg J, ..., Sandberg M, Czene K
Breast Cancer Res. Treat. 151 (2) 319-324 [2015-06-00; online 2015-04-29]
Variants in ELL2 influencing immunoglobulin levels associate with multiple myeloma.
Swaminathan B, Thorleifsson G, Jöud M, ..., Thorsteinsdóttir U, Nilsson B
Nat Commun 6 (1) 7213 [2015-05-26; online 2015-05-26]
Estrogen Receptor β2 Induces Hypoxia Signature of Gene Expression by Stabilizing HIF-1α in Prostate Cancer.
Dey P, Velazquez-Villegas LA, Faria M, ..., Gustafsson JÅ, Ström AM
PLoS ONE 10 (5) e0128239 [2015-05-26; online 2015-05-26]
Understanding thio-effects in simple phosphoryl systems: role of solvent effects and nucleophile charge.
Carvalho AT, O'Donoghue AC, Hodgson DR, Kamerlin SC
Org. Biomol. Chem. 13 (19) 5391-5398 [2015-05-21; online 2015-03-24]
Spectral imaging to measure heterogeneity in membrane lipid packing.
Sezgin E, Waithe D, Bernardino de la Serna J, Eggeling C
Chemphyschem 16 (7) 1387-1394 [2015-05-18; online 2015-03-05]
Erdinc Sezgin SciLifeLab Fellow
CGGBP1 mitigates cytosine methylation at repetitive DNA sequences.
Agarwal P, Collier P, Fritz MH, ..., Westermark B, Singh U
BMC Genomics 16 (1) 390 [2015-05-16; online 2015-05-16]
Obesity, metabolic syndrome and risk of atrial fibrillation: a Swedish, prospective cohort study.
Nyström PK, Carlsson AC, Leander K, ..., Hellenius ML, Gigante B
PLoS ONE 10 (5) e0127111 [2015-05-15; online 2015-05-15]
Differential protein expression profiles of cyst fluid from papillary thyroid carcinoma and benign thyroid lesions.
Dinets A, Pernemalm M, Kjellin H, ..., Lehtiö J, Höög A
PLoS ONE 10 (5) e0126472 [2015-05-15; online 2015-05-15]
Complex archaea that bridge the gap between prokaryotes and eukaryotes.
Spang A, Saw JH, Jørgensen SL, ..., Guy L, Ettema TJG
Nature 521 (7551) 173-179 [2015-05-14; online 2015-05-06]
Vinylic MIDA Boronates: New Building Blocks for the Synthesis of Aza-Heterocycles.
Llona-Minguez S, Desroses M, Ghassemian A, ..., Scobie M, Helleday T
Chemistry 21 (20) 7394-7398 [2015-05-11; online 2015-03-25]
Functionally Structured Genomes in Lactobacillus kunkeei Colonizing the Honey Crop and Food Products of Honeybees and Stingless Bees.
Tamarit D, Ellegaard KM, Wikander J, ..., Vásquez A, Andersson SG
Genome Biol Evol 7 (6) 1455-1473 [2015-05-06; online 2015-05-06]
Somatostatin Analogs Treated Small Intestinal Neuroendocrine Tumor Patients Circulating MicroRNAs.
Li SC, Khan M, Caplin M, ..., Öberg K, Giandomenico V
PLoS ONE 10 (5) e0125553 [2015-05-05; online 2015-05-05]
Intestinal dysbiosis in children with short bowel syndrome is associated with impaired outcome.
Engstrand Lilja H, Wefer H, Nyström N, Finkel Y, Engstrand L
Microbiome 3 (-) 18 [2015-05-04; online 2015-05-04]
RhoD is a Golgi component with a role in anterograde protein transport from the ER to the plasma membrane.
Blom M, Reis K, Nehru V, ..., Gad AKB, Aspenström P
Exp. Cell Res. 333 (2) 208-219 [2015-05-01; online 2015-03-05]
Coordinated expression of DNAM-1 and LFA-1 in educated NK cells.
Enqvist M, Ask EH, Forslund E, ..., Önfelt B, Malmberg KJ
J. Immunol. 194 (9) 4518-4527 [2015-05-01; online 2015-03-30]
A systematic investigation of the contribution of genetic variation within the MHC region to HPV seropositivity.
Chen D, Gaborieau V, Zhao Y, ..., Brennan P, McKay JD
Hum. Mol. Genet. 24 (9) 2681-2688 [2015-05-01; online 2015-01-23]
When pigs fly, UCP1 makes heat.
Jastroch M, Andersson L
Mol Metab 4 (5) 359-362 [2015-05-00; online 2015-02-18]
Tracking the origin of metastatic prostate cancer.
Lindberg J, Kristiansen A, Wiklund P, Grönberg H, Egevad L
Eur. Urol. 67 (5) 819-822 [2015-05-00; online 2014-09-22]
The tyrosine kinase inhibitors imatinib and dasatinib reduce myeloid suppressor cells and release effector lymphocyte responses.
Christiansson L, Söderlund S, Mangsbo S, ..., Loskog A, Olsson-Strömberg U
Mol. Cancer Ther. 14 (5) 1181-1191 [2015-05-00; online 2015-03-11]
Recent advances in QM/MM free energy calculations using reference potentials.
Duarte F, Amrein BA, Blaha-Nelson D, Kamerlin SCL
Biochim. Biophys. Acta 1850 (5) 954-965 [2015-05-00; online 2014-07-16]
Quantifying the impact of transporters on cellular drug permeability.
Matsson P, Fenu LA, Lundquist P, ..., Kansy M, Artursson P
Trends Pharmacol. Sci. 36 (5) 255-262 [2015-05-00; online 2015-03-19]
Predictors of recurrent cellulitis in five years. Clinical risk factors and the role of PTX3 and CRP.
Karppelin M, Siljander T, Aittoniemi J, ..., Vuopio J, Syrjänen J
J. Infect. 70 (5) 467-473 [2015-05-00; online 2014-11-15]
NOTA: a potent metallo-β-lactamase inhibitor.
Somboro AM, Tiwari D, Bester LA, ..., Naicker T, Essack SY
J Antimicrob Chemother 70 (5) 1594-1596 [2015-05-00; online 2015-01-06]
Mass-spectrometry-based characterization of oxidations in proteins.
Artemenko K, Mi J, Bergquist J
Free Radic. Res. 49 (5) 477-493 [2015-05-00; online 2015-04-17]
ITS1: a DNA barcode better than ITS2 in eukaryotes?
Wang XC, Liu C, Huang L, ..., Cai D, Li JQ
Mol Ecol Resour 15 (3) 573-586 [2015-05-00; online 2014-09-24]
DDLS Fellow Johan Bengtsson-Palme
Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption.
Coffee and Caffeine Genetics Consortium , Cornelis MC, Byrne EM, ..., van Dam RM, Chasman DI
Mol. Psychiatry 20 (5) 647-656 [2015-05-00; online 2014-10-07]
Evolutionary histories of transposable elements in the genome of the largest living marsupial carnivore, the Tasmanian devil.
Gallus S, Hallström BM, Kumar V, ..., Schumann GG, Nilsson MA
Mol. Biol. Evol. 32 (5) 1268-1283 [2015-05-00; online 2015-01-28]
Diagnostic urinary proteome profile for immunoglobulin a nephropathy.
Samavat S, Kalantari S, Nafar M, ..., Parvin M, Zubarev RA
Iran J Kidney Dis 9 (3) 239-248 [2015-05-00; online 2015-05-10]
Affiliated researcher
Autosomal recessive mutations in the COL2A1 gene cause severe spondyloepiphyseal dysplasia.
Tham E, Nishimura G, Geiberger S, ..., Nordenskjöld M, Grigelioniene G
Clin. Genet. 87 (5) 496-498 [2015-05-00; online 2014-09-08]
Autoantibody response against NALP5/MATER in primary ovarian insufficiency and in autoimmune Addison's disease.
Brozzetti A, Alimohammadi M, Morelli S, ..., Falorni A, Italian Addison Network
J. Clin. Endocrinol. Metab. 100 (5) 1941-1948 [2015-05-00; online 2015-03-03]
Age- and sex-specific causal effects of adiposity on cardiovascular risk factors.
Fall T, Hägg S, Ploner A, ..., Ingelsson E, ENGAGE Consortium
Diabetes 64 (5) 1841-1852 [2015-05-00; online 2015-02-23]
African origin for Madagascan dogs revealed by mtDNA analysis.
Ardalan A, Oskarsson MC, van Asch B, Rabakonandriania E, Savolainen P
R Soc Open Sci 2 (5) 140552 [2015-05-00; online 2015-05-20]
Nanoparticle-stabilized microbubbles for multimodal imaging and drug delivery.
Mørch Ý, Hansen R, Berg S, ..., de Lange Davies C, Stenstad PM
Contrast Media Mol Imaging 10 (5) 356-366 [2015-04-30; online 2015-04-30]
An epigenome-wide association study of total serum immunoglobulin E concentration.
Liang L, Willis-Owen SAG, Laprise C, ..., Moffatt MF, Cookson WOCM
Nature 520 (7549) 670-674 [2015-04-30; online 2015-02-18]
Single-Cell Characterization of in vitro Migration and Interaction Dynamics of T Cells Expanded with IL-2 and IL-7.
Tauriainen J, Gustafsson K, Göthlin M, ..., Uhlin M, Önfelt B
Front Immunol 6 (-) 196 [2015-04-28; online 2015-04-28]
Frequency and distribution of Notch mutations in tumor cell lines.
Mutvei AP, Fredlund E, Lendahl U
BMC Cancer 15 (-) 311 [2015-04-25; online 2015-04-25]
Membrane nanoclusters-tails of the unexpected.
Sezgin E, Davis SJ, Eggeling C
Cell 161 (3) 433-434 [2015-04-23; online 2015-04-25]
Erdinc Sezgin SciLifeLab Fellow
Genetically determined height and coronary artery disease.
Nelson CP, Hamby SE, Saleheen D, ..., Samani NJ, CARDIoGRAM+C4D Consortium
N. Engl. J. Med. 372 (17) 1608-1618 [2015-04-23; online 2015-04-08]
Adaptive lipid packing and bioactivity in membrane domains.
Sezgin E, Gutmann T, Buhl T, ..., Levental I, Schwille P
PLoS ONE 10 (4) e0123930 [2015-04-23; online 2015-04-23]
Erdinc Sezgin SciLifeLab Fellow
Fast and sensitive total protein and Peptide assays for proteomic analysis.
Wiśniewski JR, Gaugaz FZ
Anal. Chem. 87 (8) 4110-4116 [2015-04-21; online 2015-04-09]
Circulating carnosine dipeptidase 1 associates with weight loss and poor prognosis in gastrointestinal cancer.
Arner P, Henjes F, Schwenk JM, ..., Nilsson P, Rydén M
PLoS ONE 10 (4) e0123566 [2015-04-21; online 2015-04-21]
Solid-phase cloning for high-throughput assembly of single and multiple DNA parts.
Lundqvist M, Edfors F, Sivertsson Å, ..., Uhlén M, Rockberg J
Nucleic Acids Res. 43 (7) e49 [2015-04-20; online 2015-01-23]
Exploration of the arrest peptide sequence space reveals arrest-enhanced variants.
Cymer F, Hedman R, Ismail N, von Heijne G
J Biol Chem 290 (16) 10208-10215 [2015-04-17; online 2015-02-24]
Extensive intra-phylotype diversity in lactobacilli and bifidobacteria from the honeybee gut.
Ellegaard KM, Tamarit D, Javelind E, ..., Andersson SG, Vásquez A
BMC Genomics 16 (1) 284 [2015-04-11; online 2015-04-11]
Synthesis and bioactivity of β-substituted fosmidomycin analogues targeting 1-deoxy-D-xylulose-5-phosphate reductoisomerase.
Chofor R, Sooriyaarachchi S, Risseeuw MD, ..., Mowbray SL, Van Calenbergh S
J Med Chem 58 (7) 2988-3001 [2015-04-09; online 2015-03-31]
The structure of the human mitochondrial ribosome
Amunts A, Brown A, Toots J, Scheres SHW, Ramakrishnan V
Science 348 (6230) 95-98 [2015-04-03; online 2015-04-02]
Alexey Amunts SciLifeLab Fellow
An entity evolving into a community: defining the common ancestor and evolutionary trajectory of chronic lymphocytic leukemia stereotyped subset #4.
Sutton LA, Papadopoulos G, Hadzidimitriou A, ..., Tzovaras D, Stamatopoulos K
Mol. Med. 20 (1) 720-728 [2015-04-02; online 2015-04-02]
Behavioral cost & overdominance in Anopheles gambiae.
Diop MM, Moiroux N, Chandre F, ..., Labbé P, Pennetier C
PLoS ONE 10 (4) e0121755 [2015-04-01; online 2015-04-01]
Pascal Milesi SciLifeLab Fellow
RIFINs are adhesins implicated in severe Plasmodium falciparum malaria.
Goel S, Palmkvist M, Moll K, ..., Nilsson I, Wahlgren M
Nat. Med. 21 (4) 314-317 [2015-04-00; online 2015-03-09]
Nanoclusters of the resting T cell antigen receptor (TCR) localize to non-raft domains.
Beck-García K, Beck-García E, Bohler S, ..., Alarcón B, Schamel WW
Biochim. Biophys. Acta 1853 (4) 802-809 [2015-04-00; online 2014-12-20]
Erdinc Sezgin SciLifeLab Fellow
Molecular histology of lung cancer: from targets to treatments.
Wood SL, Pernemalm M, Crosbie PA, Whetton AD
Cancer Treat. Rev. 41 (4) 361-375 [2015-04-00; online 2015-02-20]
Microfluidic-based isolation of bacteria from whole blood for sepsis diagnostics.
Zelenin S, Hansson J, Ardabili S, ..., Brismar H, Russom A
Biotechnol. Lett. 37 (4) 825-830 [2015-04-00; online 2014-11-21]
Lysophosphatidic acid receptor (LPAR) modulators: The current pharmacological toolbox.
Llona-Minguez S, Ghassemian A, Helleday T
Prog. Lipid Res. 58 (-) 51-75 [2015-04-00; online 2015-02-20]
Functional anti-CD94/NKG2A and anti-CD94/NKG2C autoantibodies in patients with systemic lupus erythematosus.
Hagberg N, Theorell J, Hjorton K, ..., Bryceson YT, Rönnblom L
Arthritis & rheumatology (Hoboken, N.J.) 67 (4) 1000-1011 [2015-04-00; online 2014-12-17]
Evidence of streptococcal origin of acute non-necrotising cellulitis: a serological study.
Karppelin M, Siljander T, Haapala AM, ..., Vuopio J, Syrjänen J
Eur. J. Clin. Microbiol. Infect. Dis. 34 (4) 669-672 [2015-04-00; online 2014-11-18]
Duffy antigen receptor genetic variant and the association with Interleukin 8 levels.
Moreno Velásquez I, Kumar J, Björkbacka H, ..., de Faire U, Gigante B
Cytokine 72 (2) 178-184 [2015-04-00; online 2015-01-31]
Calcium signaling in neocortical development.
Uhlén P, Fritz N, Smedler E, Malmersjö S, Kanatani S
Dev Neurobiol 75 (4) 360-368 [2015-04-00; online 2015-02-18]
Adiposity as a cause of cardiovascular disease: a Mendelian randomization study.
Hägg S, Fall T, Ploner A, ..., Ingelsson E, European Network for Genetic and Genomic Epidemiology Consortium
Int J Epidemiol 44 (2) 578-586 [2015-04-00; online 2015-05-27]
Aberrant post-translational modifications compromise human myosin motor function in old age.
Li M, Ogilvie H, Ochala J, ..., Bergquist J, Larsson L
Aging Cell 14 (2) 228-235 [2015-04-00; online 2015-02-02]
A missense change in the ATG4D gene links aberrant autophagy to a neurodegenerative vacuolar storage disease.
Kyöstilä K, Syrjä P, Jagannathan V, ..., Lohi H, Leeb T
PLoS Genet 11 (4) e1005169 [2015-04-00; online 2015-04-15]
Rewired metabolism in drug-resistant leukemia cells: a metabolic switch hallmarked by reduced dependence on exogenous glutamine.
Stäubert C, Bhuiyan H, Lindahl A, ..., Lehtiö J, Nordström A
J Biol Chem 290 (13) 8348-8359 [2015-03-27; online 2015-02-19]
Dissecting antibodies with regards to linear and conformational epitopes.
Forsström B, Axnäs BB, Rockberg J, ..., Bohlin A, Uhlen M
PLoS ONE 10 (3) e0121673 [2015-03-27; online 2015-03-27]
Catalytic stimulation by restrained active-site floppiness--the case of high density lipoprotein-bound serum paraoxonase-1.
Ben-David M, Sussman JL, Maxwell CI, ..., Kamerlin SCL, Tawfik DS
J. Mol. Biol. 427 (6 Pt B) 1359-1374 [2015-03-27; online 2015-01-30]
Affiliated researcher
Transducin duplicates in the zebrafish retina and pineal complex: differential specialisation after the teleost tetraploidisation.
Lagman D, Callado-Pérez A, Franzén IE, Larhammar D, Abalo XM
PLoS ONE 10 (3) e0121330 [2015-03-25; online 2015-03-25]
Crystal structures of the kinase domain of the sulfate-activating complex in Mycobacterium tuberculosis.
Poyraz Ö, Brunner K, Lohkamp B, ..., Schnell R, Schneider G
PLoS ONE 10 (3) e0121494 [2015-03-25; online 2015-03-25]
Coordinated international action to accelerate genome-to-phenome with FAANG, the Functional Annotation of Animal Genomes project.
Andersson L, Archibald AL, Bottema CD, ..., Zhou H, FAANG Consortium
Genome Biol. 16 (1) 57 [2015-03-25; online 2015-03-25]
Molecular docking screening using agonist-bound GPCR structures: probing the A2A adenosine receptor.
Rodríguez D, Gao ZG, Moss SM, Jacobson KA, Carlsson J
J Chem Inf Model 55 (3) 550-563 [2015-03-23; online 2015-02-13]
Chondroitin / dermatan sulfate modification enzymes in zebrafish development.
Habicher J, Haitina T, Eriksson I, ..., Ahlberg PE, Ledin J
PLoS ONE 10 (3) e0121957 [2015-03-20; online 2015-03-20]
No redistribution of lung blood flow by inhaled nitric oxide in endotoxemic piglets pretreated with an endothelin receptor antagonist.
Trachsel S, Hambraeus-Jonzon K, Bergquist M, ..., Chen L, Hedenstierna G
J. Appl. Physiol. 118 (6) 768-775 [2015-03-15; online 2014-12-30]
Microsatellite instability and mutations in BRAF and KRAS are significant predictors of disseminated disease in colon cancer.
Birgisson H, Edlund K, Wallin U, ..., Glimelius B, Sundström M
BMC Cancer 15 (-) 125 [2015-03-14; online 2015-03-14]
The NDST gene family in zebrafish: role of NDST1B in pharyngeal arch formation.
Filipek-Górniok B, Carlsson P, Haitina T, ..., Ledin J, Kjellén L
PLoS ONE 10 (3) e0119040 [2015-03-13; online 2015-03-13]
Mechanisms of integral membrane protein insertion and folding.
Cymer F, von Heijne G, White SH
J. Mol. Biol. 427 (5) 999-1022 [2015-03-13; online 2014-09-30]
Affiliated researcher
Computational and molecular tools for scalable rAAV-mediated genome editing.
Stoimenov I, Ali MA, Pandzic T, Sjöblom T
Nucleic Acids Res. 43 (5) e30 [2015-03-11; online 2014-12-08]
Microglia-Secreted Galectin-3 Acts as a Toll-like Receptor 4 Ligand and Contributes to Microglial Activation.
Burguillos MA, Svensson M, Schulte T, ..., Joseph B, Deierborg T
Cell Reports 10 (9) 1626-1638 [2015-03-10; online 2015-03-05]
How valence bond theory can help you understand your (bio)chemical reaction.
Shurki A, Derat E, Barrozo A, Kamerlin SC
Chem Soc Rev 44 (5) 1037-1052 [2015-03-07; online 2014-10-30]
Binding of subdomains 1/2 of PfEMP1-DBL1α to heparan sulfate or heparin mediates Plasmodium falciparum rosetting.
Angeletti D, Sandalova T, Wahlgren M, Achour A
PLoS ONE 10 (3) e0118898 [2015-03-05; online 2015-03-05]
Proteomic profiling reveals autoimmune targets in sarcoidosis.
Häggmark A, Hamsten C, Wiklundh E, ..., Grunewald J, Nilsson P
Am. J. Respir. Crit. Care Med. 191 (5) 574-583 [2015-03-01; online 2015-01-22]
Resistant microbial cooccurrence patterns inferred by network topology.
Peura S, Bertilsson S, Jones RI, Eiler A
Applied and environmental microbiology 81 (6) 2090-2097 [2015-03-00; online 2015-01-09]
Protein kinase A directly phosphorylates metabotropic glutamate receptor 5 to modulate its function.
Uematsu K, Heiman M, Zelenina M, ..., Nishi A, Greengard P
J. Neurochem. 132 (6) 677-686 [2015-03-00; online 2015-03-04]
Preclinical characterization of acyl sulfonimidamides: potential carboxylic acid bioisosteres with tunable properties.
Borhade SR, Svensson R, Brandt P, ..., Arvidsson PI, Sandström A
ChemMedChem 10 (3) 455-460 [2015-03-00; online 2015-01-28]
Plasma IL-5 concentration and subclinical carotid atherosclerosis.
Silveira A, McLeod O, Strawbridge RJ, ..., de Faire U, Hamsten A
Atherosclerosis 239 (1) 125-130 [2015-03-00; online 2014-12-23]
Pharmacotherapy and mortality in atrial fibrillation--a cohort of men and women 75 years or older in Sweden.
Wändell PE, Carlsson AC, Sundquist J, ..., Bottai M, Sundquist K
Age Ageing 44 (2) 232-238 [2015-03-00; online 2014-10-16]
Palmitate-induced impairments of β-cell function are linked with generation of specific ceramide species via acylation of sphingosine.
Manukyan L, Ubhayasekera SJ, Bergquist J, Sargsyan E, Bergsten P
Endocrinology 156 (3) 802-812 [2015-03-00; online 2014-12-23]
PXK locus in systemic lupus erythematosus: fine mapping and functional analysis reveals novel susceptibility gene ABHD6.
Oparina NY, Delgado-Vega AM, Martinez-Bueno M, ..., Alarcon-Riquelme ME, Kozyrev SV
Ann. Rheum. Dis. 74 (3) e14 [2015-03-00; online 2014-02-17]
MuSK: a new target for lethal fetal akinesia deformation sequence (FADS).
Wilbe M, Ekvall S, Eurenius K, ..., Annerén G, Bondeson ML
J. Med. Genet. 52 (3) 195-202 [2015-03-00; online 2015-01-22]
Imaging of a clinically relevant stroke model: glucose hypermetabolism revisited.
Arnberg F, Grafström J, Lundberg J, ..., Stone-Elander S, Holmin S
Stroke 46 (3) 835-842 [2015-03-00; online 2015-02-05]
FGF2 as a potential prognostic biomarker for proneural glioma patients.
Sooman L, Freyhult E, Jaiswal A, ..., Bergqvist M, Ekman S
Acta Oncol 54 (3) 385-394 [2015-03-00; online 2014-09-29]
Emerging carbon-based nanosensor devices: structures, functions and applications
Manzetti S, Vasilache D, Francesco E
Adv. Manuf. 3 (1) 63-72 [2015-03-00; online 2015-03-11]
Convergent evolution of the genomes of marine mammals.
Foote AD, Liu Y, Thomas GW, ..., Gilbert MT, Gibbs RA
Nat. Genet. 47 (3) 272-275 [2015-03-00; online 2015-01-26]
Common variation at 12q24.13 (OAS3) influences chronic lymphocytic leukemia risk.
Sava GP, Speedy HE, Di Bernardo MC, ..., Allan JM, Houlston RS
Leukemia 29 (3) 748-751 [2015-03-00; online 2014-11-03]
A genomic duplication is associated with ectopic eomesodermin expression in the embryonic chicken comb and two duplex-comb phenotypes.
Dorshorst B, Harun-Or-Rashid M, Bagherpoor AJ, ..., Hallböök F, Andersson L
PLoS Genet 11 (3) e1004947 [2015-03-00; online 2015-03-19]
Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells.
Arner E, Daub CO, Vitting-Seerup K, ..., Carninci P, Hayashizaki Y
Science (New York, N.Y.) 347 (6225) 1010-1014 [2015-02-27; online 2015-02-12]
Influence of antifreeze proteins on the ice/water interface.
Todde G, Hovmöller S, Laaksonen A
J Phys Chem B 119 (8) 3407-3413 [2015-02-26; online 2015-02-10]
Overexpression of heparanase lowers the amyloid burden in amyloid-β precursor protein transgenic mice.
Jendresen CB, Cui H, Zhang X, ..., Nilsson LNG, Li JP
J Biol Chem 290 (8) 5053-5064 [2015-02-20; online 2014-12-29]
Capture Hi-C identifies the chromatin interactome of colorectal cancer risk loci.
Jäger R, Migliorini G, Henrion M, ..., Fletcher O, Houlston RS
Nat Commun 6 (-) 6178 [2015-02-19; online 2015-02-19]
No difference in small bowel microbiota between patients with irritable bowel syndrome and healthy controls.
Dlugosz A, Winckler B, Lundin E, ..., Engstrand L, Lindberg G
Sci Rep 5 (-) 8508 [2015-02-17; online 2015-02-17]
DNA methylation-based subtype prediction for pediatric acute lymphoblastic leukemia.
Nordlund J, Bäcklin CL, Zachariadis V, ..., Forestier E, Syvänen AC
Clin Epigenetics 7 (1) 11 [2015-02-17; online 2015-02-17]
Genome-wide enrichment analysis between endometriosis and obesity-related traits reveals novel susceptibility loci.
Rahmioglu N, Macgregor S, Drong AW, ..., Lindgren CM, Zondervan KT
Hum. Mol. Genet. 24 (4) 1185-1199 [2015-02-15; online 2014-10-08]
Synthesis and characterisation of lanthanide-hydroporphyrin dyads.
Xiong R, Andres J, Scheffler K, Borbas KE
Dalton Trans 44 (6) 2541-2553 [2015-02-14; online 2014-10-24]
Ruisheng Xiong SciLifeLab Fellow
New genetic loci link adipose and insulin biology to body fat distribution.
Shungin D, Winkler TW, Croteau-Chonka DC, ..., Lindgren CM, Mohlke KL
Nature 518 (7538) 187-196 [2015-02-12; online 2015-02-13]
Genetic studies of body mass index yield new insights for obesity biology.
Locke AE, Kahali B, Berndt SI, ..., Loos RJF, Speliotes EK
Nature 518 (7538) 197-206 [2015-02-12; online 2015-02-13]
Clonal distribution of BCR-ABL1 mutations and splice isoforms by single-molecule long-read RNA sequencing.
Cavelier L, Ameur A, Häggqvist S, ..., Olsson-Strömberg U, Hermanson M
BMC Cancer 15 (-) 45 [2015-02-12; online 2015-02-12]
Deciphering solution scattering data with experimentally guided molecular dynamics simulations.
Björling A, Niebling S, Marcellini M, van der Spoel D, Westenhoff S
J Chem Theory Comput 11 (2) 780-787 [2015-02-10; online 2015-02-18]
14-3-3ζ turns TGF-β to the dark side.
ten Dijke P, van Dam H
Cancer Cell 27 (2) 151-153 [2015-02-09; online 2015-02-12]
Methods applicable to membrane nanodomain studies?
Ashrafzadeh P, Parmryd I
Essays Biochem. 57 (-) 57-68 [2015-02-07; online 2015-02-07]
Synthesis of 4-quinolones via a carbonylative Sonogashira cross-coupling using molybdenum hexacarbonyl as a CO source.
Åkerbladh L, Nordeman P, Wejdemar M, Odell LR, Larhed M
J. Org. Chem. 80 (3) 1464-1471 [2015-02-06; online 2015-01-21]
Novel readout method for molecular diagnostic assays based on optical measurements of magnetic nanobead dynamics.
Donolato M, Antunes P, Bejhed RS, ..., Hansen MF, Vavassori P
Anal. Chem. 87 (3) 1622-1629 [2015-02-03; online 2015-01-09]
Microbial community composition and diversity via 16S rRNA gene amplicons: evaluating the illumina platform.
Sinclair L, Osman OA, Bertilsson S, Eiler A
PLoS ONE 10 (2) e0116955 [2015-02-03; online 2015-02-03]
Identifying anti-growth factors for human cancer cell lines through genome-scale metabolic modeling.
Ghaffari P, Mardinoglu A, Asplund A, ..., Uhlen M, Nielsen J
Sci Rep 5 (1) 8183 [2015-02-02; online 2015-02-02]
Flagellin as carrier and adjuvant in cocaine vaccine development.
Lockner JW, Eubanks LM, Choi JL, ..., Wilson IA, Janda KD
Mol. Pharm. 12 (2) 653-662 [2015-02-02; online 2015-01-07]
Daniel Globisch SciLifeLab Fellow
Viral and cellular proteins containing FGDF motifs bind G3BP to block stress granule formation.
Panas MD, Schulte T, Thaa B, ..., Achour A, McInerney GM
PLoS Pathog 11 (2) e1004659 [2015-02-00; online 2015-02-06]
Splenic marginal-zone lymphoma: ontogeny and genetics.
Baliakas P, Strefford JC, Bikos V, ..., Stamatopoulos K, Oscier D
Leuk. Lymphoma 56 (2) 301-310 [2015-02-00; online 2014-08-19]
Recurrent mutations refine prognosis in chronic lymphocytic leukemia.
Baliakas P, Hadzidimitriou A, Sutton LA, ..., Rosenquist R, European Research Initiative on CLL (ERIC)
Leukemia 29 (2) 329-336 [2015-02-00; online 2014-06-19]
Predicting venous thrombosis in women using a combination of genetic markers and clinical risk factors.
Bruzelius M, Bottai M, Sabater-Lleal M, ..., Hamsten A, Odeberg J
J. Thromb. Haemost. 13 (2) 219-227 [2015-02-00; online 2015-01-12]
Interleukin-8 is associated with increased total mortality in women but not in men-findings from a community-based cohort of elderly.
Moreno Velásquez I, Ärnlöv J, Leander K, ..., Gigante B, Carlsson AC
Ann. Med. 47 (1) 28-33 [2015-02-00; online 2014-10-10]
Genome-wide association study identifies shared risk loci common to two malignancies in golden retrievers.
Tonomura N, Elvers I, Thomas R, ..., Breen M, Lindblad-Toh K
PLoS Genet 11 (2) e1004922 [2015-02-00; online 2015-02-02]
Genome and physiology of the ascomycete filamentous fungus Xeromyces bisporus, the most xerophilic organism isolated to date.
Leong SL, Lantz H, Pettersson OV, ..., Tellgren-Roth C, Schnürer J
Environ. Microbiol. 17 (2) 496-513 [2015-02-00; online 2014-10-07]
Expression of human skin-specific genes defined by transcriptomics and antibody-based profiling.
Edqvist PH, Fagerberg L, Hallström BM, ..., Uhlén M, Pontén F
J. Histochem. Cytochem. 63 (2) 129-141 [2015-02-00; online 2014-11-19]
Detection of glyco-mucin profiles improves specificity of MUC16 and MUC1 biomarkers in ovarian serous tumours.
Ricardo S, Marcos-Silva L, Pereira D, ..., Lunet N, David L
Mol Oncol 9 (2) 503-512 [2015-02-00; online 2014-10-22]
Charge-driven dynamics of nascent-chain movement through the SecYEG translocon.
Ismail N, Hedman R, Lindén M, von Heijne G
Nat. Struct. Mol. Biol. 22 (2) 145-149 [2015-02-00; online 2015-01-05]
CTNND2-a candidate gene for reading problems and mild intellectual disability.
Hofmeister W, Nilsson D, Topa A, ..., Syk Lundberg E, Lindstrand A
J. Med. Genet. 52 (2) 111-122 [2015-02-00; online 2014-12-03]
Bactobolin A Binds to a Site on the 70S Ribosome Distinct from Previously Seen Antibiotics
Amunts A, Fiedorczuk K, Truong TT, ..., Greenberg EP, Ramakrishnan V
Journal of Molecular Biology 427 (4) 753-755 [2015-02-00; online 2015-02-00]
Alexey Amunts SciLifeLab Fellow
A general method for rapid determination of antibiotic susceptibility and species in bacterial infections.
Mezger A, Gullberg E, Göransson J, ..., Nilsson M, Andersson DI
J. Clin. Microbiol. 53 (2) 425-432 [2015-02-00; online 2014-11-19]
Chromatin-dependent regulation of RNA polymerases II and III activity throughout the transcription cycle
Jordán-Pla A, Gupta I, de Miguel-Jiménez L, ..., Pelechano V, Pérez-Ortín JE
Nucleic Acids Res. 43 (2) 787-802 [2015-01-30; online 2014-12-29]
SciLifeLab Fellow Vicent Pelechano
Not all IGHV3-21 chronic lymphocytic leukemias are equal: prognostic considerations.
Baliakas P, Agathangelidis A, Hadzidimitriou A, ..., Rosenquist R, Stamatopoulos K
Blood 125 (5) 856-859 [2015-01-29; online 2014-12-17]
Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility.
Wessel J, Chu AY, Willems SM, ..., Scott RA, Goodarzi MO
Nat Commun 6 (-) 5897 [2015-01-29; online 2015-01-29]
Endonuclease specificity and sequence dependence of type IIS restriction enzymes.
Lundin S, Jemt A, Terje-Hegge F, ..., Lexow P, Lundeberg J
PLoS ONE 10 (1) e0117059 [2015-01-28; online 2015-01-28]
Intratumoral genome diversity parallels progression and predicts outcome in pediatric cancer.
Mengelbier LH, Karlsson J, Lindgren D, ..., Mayrhofer M, Gisselsson D
Nat Commun 6 (-) 6125 [2015-01-27; online 2015-01-27]
Scaling predictive modeling in drug development with cloud computing.
Moghadam BT, Alvarsson J, Holm M, ..., Carlsson L, Spjuth O
J Chem Inf Model 55 (1) 19-25 [2015-01-26; online 2015-01-08]
HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials.
Swerdlow DI, Preiss D, Kuchenbaecker KB, ..., Hingorani AD, Sattar N
The Lancet 385 (9965) 351-361 [2015-01-24; online 2014-09-24]
Proteomics. Tissue-based map of the human proteome.
Uhlén M, Fagerberg L, Hallström BM, ..., Nielsen J, Pontén F
Science (New York, N.Y.) 347 (6220) 1260419 [2015-01-23; online 2015-01-24]
Ancestral vertebrate complexity of the opioid system.
Larhammar D, Bergqvist C, Sundström G
Vitam Horm 97 (-) 95-122 [2015-01-23; online 2015-01-23]
The mutational landscapes of genetic and chemical models of Kras-driven lung cancer.
Westcott PM, Halliwill KD, To MD, ..., Adams DJ, Balmain A
Nature 517 (7535) 489-492 [2015-01-22; online 2014-11-02]
Coupled diffusion in lipid bilayers upon close approach.
Pronk S, Lindahl E, Kasson PM
Journal of the American Chemical Society 137 (2) 708-714 [2015-01-21; online 2015-01-06]
Biological interpretation of genome-wide association studies using predicted gene functions.
Pers TH, Karjalainen JM, Chan Y, ..., Hirschhorn JN, Franke L
Nat Commun 6 (-) 5890 [2015-01-19; online 2015-01-19]
Variation in the human immune system is largely driven by non-heritable influences.
Brodin P, Jojic V, Gao T, ..., Maecker HT, Davis MM
Cell 160 (1-2) 37-47 [2015-01-15; online 2015-01-17]
The human otubain2-ubiquitin structure provides insights into the cleavage specificity of poly-ubiquitin-linkages.
Altun M, Walter TS, Kramer HB, ..., Ren J, Kessler BM
PLoS ONE 10 (1) e0115344 [2015-01-15; online 2015-01-15]
A proteomic approach to monitor the dynamic response of the female oviductal epithelial cell surface to male gametes.
Artemenko K, Horáková J, Steinberger B, ..., Bergquist J, Mayrhofer C
J Proteomics 113 (-) 1-14 [2015-01-15; online 2014-10-02]
Dual channel RESOLFT nanoscopy by using fluorescent state kinetics.
Testa I, D'Este E, Urban NT, Balzarotti F, Hell SW
Nano Lett. 15 (1) 103-106 [2015-01-14; online 2014-12-02]
Ilaria Testa SciLifeLab Fellow
Pan-vertebrate comparative genomics unmasks retrovirus macroevolution.
Hayward A, Cornwallis CK, Jern P
Proc. Natl. Acad. Sci. U.S.A. 112 (2) 464-469 [2015-01-13; online 2014-12-22]
A high-throughput ChIP-Seq for large-scale chromatin studies.
Chabbert CD, Adjalley SH, Klaus B, ..., Pelechano V, Steinmetz LM
Mol Syst Biol 11 (1) 777 [2015-01-12; online 2015-01-12]
SciLifeLab Fellow Vicent Pelechano
The origin and evolution of maize in the Southwestern United States.
da Fonseca RR, Smith BD, Wales N, ..., Ross-Ibarra J, Gilbert MT
Nat Plants 1 (-) 14003 [2015-01-08; online 2015-01-08]
Multiscale simulations of human telomeric G-quadruplex DNA.
Rebič M, Mocci F, Laaksonen A, Uličný J
J Phys Chem B 119 (1) 105-113 [2015-01-08; online 2014-12-17]
DCDC2 mutations cause a renal-hepatic ciliopathy by disrupting Wnt signaling.
Schueler M, Braun DA, Chandrasekar G, ..., Kere J, Hildebrandt F
Am. J. Hum. Genet. 96 (1) 81-92 [2015-01-08; online 2014-12-31]
TRIM28 represses transcription of endogenous retroviruses in neural progenitor cells.
Fasching L, Kapopoulou A, Sachdeva R, ..., Trono D, Jakobsson J
Cell Reports 10 (1) 20-28 [2015-01-06; online 2014-12-24]
Mutagenesis. Smoking is associated with mosaic loss of chromosome Y.
Dumanski JP, Rasi C, Lönn M, ..., Ingelsson E, Forsberg LA
Science (New York, N.Y.) 347 (6217) 81-83 [2015-01-02; online 2014-12-04]
A secretagogin locus of the mammalian hypothalamus controls stress hormone release.
Romanov RA, Alpár A, Zhang MD, ..., Hökfelt T, Harkany T
EMBO J. 34 (1) 36-54 [2015-01-02; online 2014-11-27]
The influence of light and water mass on bacterial population dynamics in the Amundsen Sea Polynya
Richert I, Dinasquet J, Logares R, ..., Wendeberg A, Bertilsson S
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Characterization of peptide QRFP (26RFa) and its receptor from amphioxus, Branchiostoma floridae.
Xu B, Bergqvist CA, Sundström G, ..., Leprince J, Larhammar D
Gen. Comp. Endocrinol. 210 (-) 107-113 [2015-01-01; online 2014-10-25]
VEGF suppresses T-lymphocyte infiltration in the tumor microenvironment through inhibition of NF-κB-induced endothelial activation.
Huang H, Langenkamp E, Georganaki M, ..., Kreuger J, Dimberg A
FASEB J. 29 (1) 227-238 [2015-01-00; online 2014-10-31]
The mutational landscape in pediatric acute lymphoblastic leukemia deciphered by whole genome sequencing.
Lindqvist CM, Nordlund J, Ekman D, ..., Syvänen AC, Berglund EC
Hum. Mutat. 36 (1) 118-128 [2015-01-00; online 2014-10-31]
The Biobanking Analysis Resource Catalogue (BARCdb): a new research tool for the analysis of biobank samples.
Galli J, Oelrich J, Taussig MJ, ..., Ortega-Paino E, Landegren U
Nucleic Acids Res. 43 (Database issue) D1158-D1162 [2015-01-00; online 2014-10-21]
Spatially resolved transcriptomics and beyond.
Crosetto N, Bienko M, van Oudenaarden A
Nat. Rev. Genet. 16 (1) 57-66 [2015-01-00; online 2014-12-02]
Reprogramming of Yersinia from virulent to persistent mode revealed by complex in vivo RNA-seq analysis.
Avican K, Fahlgren A, Huss M, ..., Dersch P, Fällman M
PLoS Pathog 11 (1) e1004600 [2015-01-00; online 2015-01-15]
InParanoid 8: orthology analysis between 273 proteomes, mostly eukaryotic.
Sonnhammer EL, Östlund G
Nucleic Acids Res. 43 (Database issue) D234-D239 [2015-01-00; online 2014-11-27]
Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus.
Mahajan A, Sim X, Ng HJ, ..., Gloyn AL, T2D-GENES consortium and GoT2D consortium
PLoS Genet 11 (1) e1004876 [2015-01-00; online 2015-01-27]
Deregulated proliferation and differentiation in brain tumors.
Swartling FJ, Čančer M, Frantz A, Weishaupt H, Persson AI
Cell Tissue Res. 359 (1) 225-254 [2015-01-00; online 2014-11-23]
Combining an amyloid-beta (Aβ) cleaving enzyme inhibitor with a γ-secretase modulator results in an additive reduction of Aβ production.
Strömberg K, Eketjäll S, Georgievska B, ..., Cowburn RF, Dabrowski M
FEBS J. 282 (1) 65-73 [2015-01-00; online 2014-11-07]
Avoiding pitfalls in L1-regularised inference of gene networks.
Tjärnberg A, Nordling TE, Studham M, Nelander S, Sonnhammer EL
Mol Biosyst 11 (1) 287-296 [2015-01-00; online 2014-11-07]
A Machine Learning Approach to Explain Drug Selectivity to Soluble and Membrane Protein Targets.
Freyhult E, Gustafsson MG, Strömbergsson H
Mol Inform 34 (1) 44-52 [2015-01-00; online 2015-01-08]
Tackling Exascale Software Challenges in Molecular Dynamics Simulations with GROMACS
Páll S, Abraham MJ, Kutzner C, Hess B, Lindahl E
- - (-) 3-27 [2015-00-00; online 2015-02-19]
Pd-catalyzed C–N coupling of vinylbromides and sulfonimidamides: a facile synthesis of N′-vinylsulfonimidamides
Nandi GC, Kota SR, Wakchaure PB, ..., Naicker T, Arvidsson PI
RSC Adv. 5 (76) 62084-62090 [2015-00-00; online 2015-00-00]
On-chip ultrasonic sample preparation for cell based assays
Iranmanesh I, Ramachandraiah H, Russom A, Wiklund M
RSC Adv. 5 (91) 74304-74311 [2015-00-00; online 2015-00-00]
Intriguing properties of unusual silicon nanocrystals
Manzetti S, Lu T, Behzadi H, ..., Thi Le HL, Vach H
RSC Adv. 5 (95) 78192-78208 [2015-00-00; online 2015-00-00]
Interpretation of Conformal Prediction Classification Models
Ahlberg E, Spjuth O, Hasselgren C, Carlsson L
- - (-) 323-334 [2015-00-00; online 2015-04-03]
Gap Filling as Exact Path Length Problem
Salmela L, Sahlin K, Mäkinen V, Tomescu AI
- - (-) 281-292 [2015-00-00; online 2015-03-26]
Functional porous membranes from amorphous linear dendritic polyester hybrids
Mongkhontreerat S, Walter MV, Cai Y, ..., Hult A, Malkoch M
Polym. Chem. 6 (13) 2390-2395 [2015-00-00; online 2015-00-00]
Discovery of trace amine-associated receptor 1 ligands by molecular docking screening against a homology model
Lam VM, Rodríguez D, Zhang T, ..., Carlsson J, Salahpour A
Med. Chem. Commun. 6 (12) 2216-2223 [2015-00-00; online 2015-00-00]
Correction: Intriguing properties of unusual silicon nanocrystals
Manzetti S, Lu T, Behzadi H, ..., Thi Le HL, Vach H
RSC Adv. 5 (100) 82631-82631 [2015-00-00; online 2015-00-00]

Publications 9.5.1