Publications 2019

Table
JSON
CSV
XLSX
TXT

789 publications

PubMed DOI Crossref
Circulating Tissue Factor-Positive Procoagulant Microparticles in Patients with Type 1 Diabetes.
Zhang C, Ou Q, Gu Y, ..., Meng W, Li S
Diabetes Metab Syndr Obes 12 (-) 2819-2828 [2019-12-31; online 2019-12-31]
PubMed DOI Crossref
Real time large scale in vivo observations reveal intrinsic synchrony, plasticity and growth cone dynamics of midline crossing axons at the ventral floor plate of the zebrafish spinal cord.
Andersen SSL
J Integr Neurosci 18 (4) 351-368 [2019-12-30; online 2020-01-09]
DOI Crossref
z-STED imaging and spectroscopy to investigate nanoscale membrane structure and dynamics
Barbotin A, Urbančič I, Galiani S, ..., Booth M, Sezgin E
- - (-) - [2019-12-28; online 2019-12-28]
DOI Crossref
Quantum Phenomena in Nanomaterials: Coherent Superpositions of Fine Structure States in CdSe Nanocrystals at Room Temperature
Collini E, Gattuso H, Bolzonello L, ..., Striccoli M, Remacle F
J. Phys. Chem. C 123 (51) 31286-31293 [2019-12-26; online 2019-12-02]
PubMed DOI Crossref
The Heat Shock Response in Yeast Maintains Protein Homeostasis by Chaperoning and Replenishing Proteins.
Mühlhofer M, Berchtold E, Stratil CG, ..., Zimmer R, Buchner J
Cell Reports 29 (13) 4593-4607.e8 [2019-12-24; online 2019-12-26]
DOI Crossref
Biophysical characterization of Epigallocatechin-3-Gallate effect on the cardiac sodium channel Nav1.5
AMAROUCH MY, Kurt MH, Delemotte L, Abriel H
- - (-) - [2019-12-24; online 2019-12-24]
PubMed DOI Crossref
SMO-M2 mutation does not support cell-autonomous Hedgehog activity in cerebellar granule cell precursors.
Petroni M, Sahùn Roncero M, Ramponi V, ..., De Smaele E, Giannini G
Sci Rep 9 (1) 19623 [2019-12-23; online 2019-12-23]
DOI Crossref
Translational profiling of macrophages infected with Leishmania donovani identifies mTOR- and eIF4A-sensitive immune-related transcripts
Chaparro V, Leroux LP, Masvidal L, ..., Larsson O, Jaramillo M
- - (-) - [2019-12-20; online 2019-12-20]
PubMed DOI Crossref
A genome-wide transcriptomic analysis of protein-coding genes in human blood cells.
Uhlen M, Karlsson MJ, Zhong W, ..., Fagerberg L, Brodin P
Science (New York, N.Y.) 366 (6472) eaax9198 [2019-12-20; online 2019-12-21]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
High genetic diversity but no geographical structure of Aedes albopictus populations in Réunion Island.
Latreille AC, Milesi P, Magalon H, Mavingui P, Atyame CM
Parasit Vectors 12 (1) 597 [2019-12-19; online 2019-12-19]
Pascal Milesi SciLifeLab Fellow
PubMed DOI Crossref
ORF6 and ORF61 Expressing MVA Vaccines Impair Early but Not Late Latency in Murine Gammaherpesvirus MHV-68 Infection.
Samreen B, Tao S, Tischer K, Adler H, Drexler I
Front Immunol 10 (-) 2984 [2019-12-18; online 2019-12-18]
PubMed DOI Crossref
Solenodon genome reveals convergent evolution of venom in eulipotyphlan mammals.
Casewell NR, Petras D, Card DC, ..., Undheim EAB, Turvey ST
Proc. Natl. Acad. Sci. U.S.A. 116 (51) 25745-25755 [2019-12-17; online 2019-11-26]
PubMed DOI Crossref
Comparative genomics study reveals Red Sea Bacillus with characteristics associated with potential microbial cell factories (MCFs).
Othoum G, Prigent S, Derouiche A, ..., Mijakovic I, Essack M
Sci Rep 9 (1) 19254 [2019-12-17; online 2019-12-17]
DOI Crossref
Ancient microRNA profiles of a 14,300-year-old canid are taxonomically informative and give glimpses into gene regulation from the Pleistocene
Fromm B, Tarbier M, Smith O, ..., Gilbert MTP, Friedländer MR
- - (-) - [2019-12-17; online 2019-12-17]
PubMed DOI Crossref
Sex differences in clinical presentation of systemic lupus erythematosus.
Ramírez Sepúlveda JI, Bolin K, Mofors J, ..., Gunnarsson I, Wahren-Herlenius M
Biol Sex Differ 10 (1) 60 [2019-12-16; online 2019-12-16]
PubMed DOI Crossref
Lamin A/C promotes DNA base excision repair.
Maynard S, Keijzers G, Akbari M, ..., Bartek J, Bohr VA
Nucleic Acids Res. 47 (22) 11709-11728 [2019-12-16; online 2019-10-28]
PubMed DOI Crossref
Trastuzumab cotreatment improves survival of mice with PC-3 prostate cancer xenografts treated with the GRPR antagonist 177 Lu-DOTAGA-PEG2 -RM26.
Mitran B, Rinne SS, Konijnenberg MW, ..., Rosenström U, Orlova A
Int. J. Cancer 145 (12) 3347-3358 [2019-12-15; online 2019-05-23]
PubMed DOI Crossref
MPRAscore: robust and non-parametric analysis of massively parallel reporter assays.
Niroula A, Ajore R, Nilsson B
Bioinformatics 35 (24) 5351-5353 [2019-12-15; online 2019-07-31]
Abhishek Niroula DDLS Fellow
DOI Crossref
Informing Pharmacokinetic Models with Physiological Data: Oral Population Modeling of L-Serine in Humans
Bosley JR, Björnson E, Zhang C, ..., Boren J, Mardinoglu A
- - (-) - [2019-12-14; online 2019-12-14]
DOI Crossref
Spatial mapping of cell types by integration of transcriptomics data
Andersson A, Bergenstråhle J, Asp M, ..., Navarro JF, Lundeberg J
- - (-) - [2019-12-13; online 2019-12-13]
PubMed DOI Crossref
Oral Microbiota Development in Early Childhood.
Kennedy B, Peura S, Hammar U, ..., Bertilsson S, Fall T
Sci Rep 9 (1) 19025 [2019-12-13; online 2019-12-13]
PubMed DOI Crossref
Antibiotic Uptake Across Gram-Negative Outer Membranes: Better Predictions Towards Better Antibiotics.
Ferreira RJ, Kasson PM
ACS Infect Dis 5 (12) 2096-2104 [2019-12-13; online 2019-10-25]
PubMed DOI Crossref
Nucleotide composition of transposable elements likely contributes to AT/GC compositional homogeneity of teleost fish genomes.
Symonová R, Suh A
Mobile DNA 10 (-) 49 [2019-12-12; online 2019-12-12]
PubMed DOI Crossref
Exploring inflammatory signatures in arthritic joint biopsies with Spatial Transcriptomics.
Carlberg K, Korotkova M, Larsson L, ..., Ståhl PL, Malmström V
Sci Rep 9 (1) 18975 [2019-12-12; online 2019-12-12]
PubMed DOI Crossref
A Spatiotemporal Organ-Wide Gene Expression and Cell Atlas of the Developing Human Heart.
Asp M, Giacomello S, Larsson L, ..., Sylvén C, Lundeberg J
Cell 179 (7) 1647-1660.e19 [2019-12-12; online 2019-12-14]
Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
Sphingosine-1-Phosphate Receptor 1 Activity Promotes Tumor Growth by Amplifying VEGF-VEGFR2 Angiogenic Signaling.
Balaji Ragunathrao VA, Anwar M, Akhter MZ, ..., Malik AB, Mehta D
Cell Reports 29 (11) 3472-3487.e4 [2019-12-10; online 2019-12-12]
PubMed DOI Crossref
Rotational and Translational Diffusion of Proteins as a Function of Concentration.
Bashardanesh Z, Elf J, Zhang H, van der Spoel D
ACS Omega 4 (24) 20654-20664 [2019-12-10; online 2019-11-27]
PubMed DOI Crossref
InfleCS: Clustering Free Energy Landscapes with Gaussian Mixtures.
Westerlund AM, Delemotte L
J Chem Theory Comput 15 (12) 6752-6759 [2019-12-10; online 2019-11-07]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
A Deep Learning Framework for Predicting Response to Therapy in Cancer.
Sakellaropoulos T, Vougas K, Narang S, ..., Tsirigos A, Gorgoulis VG
Cell Reports 29 (11) 3367-3373.e4 [2019-12-10; online 2019-12-12]
PubMed DOI Crossref
DNA translocation to giant unilamellar vesicles during electroporation is independent of DNA size.
Sachdev S, Muralidharan A, Choudhary DK, ..., Kreutzer MT, Boukany PE
Soft Matter 15 (45) 9187-9194 [2019-12-07; online 2019-10-09]
PubMed DOI Crossref
Progress on Identifying and Characterizing the Human Proteome: 2019 Metrics from the HUPO Human Proteome Project.
Omenn GS, Lane L, Overall CM, ..., Baker MS, Deutsch EW
J. Proteome Res. 18 (12) 4098-4107 [2019-12-06; online 2019-09-13]
PubMed DOI Crossref
CD8+ γδ T Cells Are More Frequent in CMV Seropositive Bone Marrow Grafts and Display Phenotype of an Adaptive Immune Response.
Gaballa A, Arruda LCM, Rådestad E, Uhlin M
Stem Cells Int 2019 (-) 6348060 [2019-12-06; online 2019-12-06]
PubMed DOI Crossref
Efficient delipidation of a recombinant lung surfactant lipopeptide analogue by liquid-gel chromatography.
Basabe-Burgos O, Ahlström JZ, Mikolka P, ..., Curstedt T, Rising A
PLoS ONE 14 (12) e0226072 [2019-12-04; online 2019-12-04]
DOI Crossref
The Use of GC-, Codon-, and Amino Acid-frequencies to Understand the Evolutionary Forces at a Genomic Scale
Elofsson A
- - (-) - [2019-12-03; online 2019-12-03]
PubMed DOI Crossref
A2AR Transmembrane 2 Peptide Administration Disrupts the A2AR-A2AR Homoreceptor but Not the A2AR-D2R Heteroreceptor Complex: Lack of Actions on Rodent Cocaine Self-Administration.
Borroto-Escuela DO, Wydra K, Romero-Fernandez W, ..., Filip M, Fuxe K
Int J Mol Sci 20 (23) - [2019-12-03; online 2019-12-03]
DOI Crossref
Tuning antiviral CD8 T-cell response via proline-altered peptide ligand vaccination
Duru AD, Sun R, Allerbring EB, ..., Turner SJ, Achour A
- - (-) - [2019-12-02; online 2019-12-02]
PubMed DOI Crossref
HIV-1 Reverse Transcriptase Promotes Tumor Growth and Metastasis Formation via ROS-Dependent Upregulation of Twist.
Bayurova E, Jansons J, Skrastina D, ..., Gordeychuk I, Isaguliants M
Oxid Med Cell Longev 2019 (-) 6016278 [2019-12-02; online 2019-12-02]
PubMed DOI Crossref
Evaluation of Diffusion-Weighted MRI and FDG-PET/CT to Assess Response to AdCD40L treatment in Metastatic Melanoma Patients.
Schiza A, Irenaeus S, Ortiz-Nieto F, ..., Ullenhag GJ, Ahlström H
Sci Rep 9 (1) 18069 [2019-12-02; online 2019-12-02]
PubMed DOI Crossref
DNA replication and mitotic entry: A brake model for cell cycle progression.
Lemmens B, Lindqvist A
J. Cell Biol. 218 (12) 3892-3902 [2019-12-02; online 2019-11-11]
PubMed DOI Crossref
Caspase-8 modulates physiological and pathological angiogenesis during retina development.
Tisch N, Freire-Valls A, Yerbes R, ..., Augustin HG, Ruiz de Almodovar C
J. Clin. Invest. 129 (12) 5092-5107 [2019-12-02; online 2019-08-28]
PubMed DOI Crossref
Overeating Saturated Fat Promotes Fatty Liver and Ceramides Compared With Polyunsaturated Fat: A Randomized Trial.
Rosqvist F, Kullberg J, Ståhlman M, ..., Ahlström H, Risérus U
J. Clin. Endocrinol. Metab. 104 (12) 6207-6219 [2019-12-01; online 2019-08-02]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Genome-wide association analysis of 350 000 Caucasians from the UK Biobank identifies novel loci for asthma, hay fever and eczema.
Johansson Å, Rask-Andersen M, Karlsson T, Ek WE
Hum. Mol. Genet. 28 (23) 4022-4041 [2019-12-01; online 2019-07-31]
PubMed DOI Crossref
Aquatic Adaptation and Depleted Diversity: A Deep Dive into the Genomes of the Sea Otter and Giant Otter.
Beichman AC, Koepfli KP, Li G, ..., Lohmueller KE, Wayne RK
Mol. Biol. Evol. 36 (12) 2631-2655 [2019-12-01; online 2019-06-19]
PubMed DOI Crossref
Transcription-induced formation of extrachromosomal DNA during yeast ageing.
Hull RM, King M, Pizza G, ..., Vergara X, Houseley J
PLoS Biol. 17 (12) e3000471 [2019-12-00; online 2019-12-03]
DOI Crossref
The Emergence of Life
Camprubí E, de Leeuw JW, House CH, ..., Tirumalai MR, Westall F
Space Sci Rev 215 (8) - [2019-12-00; online 2019-12-12]
PubMed DOI Crossref
Processive DNA synthesis is associated with localized decompaction of constitutive heterochromatin at the sites of DNA replication and repair.
Chagin VO, Reinhart B, Becker A, ..., Leonhardt H, Cardoso MC
Nucleus 10 (1) 231-253 [2019-12-00; online 2019-11-21]
DOI Crossref
Obituary: Jonas Blomberg (1944–2019)
Medstrand P, Jern P
Retrovirology 16 (1) - [2019-12-00; online 2019-03-14]
PubMed DOI Crossref
Nordic Guidelines for Germline Predisposition to Myeloid Neoplasms in Adults: Recommendations for Genetic Diagnosis, Clinical Management and Follow-up.
Baliakas P, Tesi B, Wartiovaara-Kautto U, ..., Hellström-Lindberg E, Andersen MK
Hemasphere 3 (6) e321 [2019-12-00; online 2019-11-04]
PubMed DOI Crossref
Nascent RNA analyses: tracking transcription and its regulation.
Wissink EM, Vihervaara A, Tippens ND, Lis JT
Nat. Rev. Genet. 20 (12) 705-723 [2019-12-00; online 2019-08-09]
Anniina Vihervaara SciLifeLab Fellow
PubMed DOI Crossref
ImJoy: an open-source computational platform for the deep learning era.
Ouyang W, Mueller F, Hjelmare M, Lundberg E, Zimmer C
Nat. Methods 16 (12) 1199-1200 [2019-12-00; online 2019-11-30]
PubMed DOI Crossref
Homogeneity in the association of body mass index with type 2 diabetes across the UK Biobank: A Mendelian randomization study.
Wainberg M, Mahajan A, Kundaje A, ..., Sinnott-Armstrong N, Rivas MA
PLoS Med. 16 (12) e1002982 [2019-12-00; online 2019-12-10]
PubMed DOI Crossref
Homeostasis in the Central Dogma of molecular biology: the importance of mRNA instability.
Pérez-Ortín JE, Tordera V, Chávez S
RNA Biol 16 (12) 1659-1666 [2019-12-00; online 2019-09-02]
PubMed DOI Crossref
Highly hydrophilic cationic gold nanorods stabilized by novel quaternary ammonium surfactant with negligible cytotoxicity.
Salajkova S, Sramek M, Malinak D, ..., Zarska M, Kuca K
J Biophotonics 12 (12) e201900024 [2019-12-00; online 2019-07-23]
DOI Crossref
High-resolution mass spectrometry (HRMS) methods for nontarget discovery and characterization of poly- and per-fluoroalkyl substances (PFASs) in environmental and human samples
Liu Y, D'Agostino LA, Qu G, Jiang G, Martin JW
TrAC Trends in Analytical Chemistry 121 (-) 115420 [2019-12-00; online 2019-12-00]
PubMed DOI Crossref
Generation of human induced pluripotent stem cell lines from patients with selective IgA deficiency.
Arias-Fuenzalida J, Yu J, Du L, ..., Hammarström L, Pan-Hammarström Q
Stem Cell Res 41 (-) 101613 [2019-12-00; online 2019-10-22]
PubMed DOI Crossref
Generation of a human induced pluripotent stem cell line (PHAi003) from a primary immunodeficient patient with CD70 mutation.
Arias-Fuenzalida J, Yu J, Abolhassani H, ..., Custodio J, Pan-Hammarström Q
Stem Cell Res 41 (-) 101612 [2019-12-00; online 2019-10-25]
PubMed DOI Crossref
Gains of Chromosome 1p and 15q are Associated with Poor Survival After Cytoreductive Surgery and HIPEC for Treating Colorectal Peritoneal Metastases.
Enblad M, Graf W, Terman A, ..., Isaksson A, Birgisson H
Ann Surg Oncol 26 (13) 4835-4842 [2019-12-00; online 2019-10-16]
DOI Crossref
Front Cover: Highly hydrophilic cationic gold nanorods stabilized by novel quaternary ammonium surfactant with negligible cytotoxicity (J. Biophotonics 12/2019)
Salajkova S, Sramek M, Malinak D, ..., Zarska M, Kuca K
Journal of Biophotonics 12 (12) - [2019-12-00; online 2019-12-09]
DOI Crossref
Fluorescence microscopy at the molecular scale
Alvelid J, Testa I
Current Opinion in Biomedical Engineering 12 (-) 34-42 [2019-12-00; online 2019-12-00]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
FGFR4 phosphorylates MST1 to confer breast cancer cells resistance to MST1/2-dependent apoptosis.
Turunen SP, von Nandelstadh P, Öhman T, ..., Varjosalo M, Lehti K
Cell Death Differ. 26 (12) 2577-2593 [2019-12-00; online 2019-03-22]
PubMed DOI Crossref
Estimation of model accuracy in CASP13.
Cheng J, Choe MH, Elofsson A, ..., Venclovas Č, Wallner B
Proteins 87 (12) 1361-1377 [2019-12-00; online 2019-07-16]
PubMed DOI Crossref
Enrichment of oral microbiota in early cystic precursors to invasive pancreatic cancer.
Gaiser RA, Halimi A, Alkharaan H, ..., Del Chiaro M, Sällberg Chen M
Gut 68 (12) 2186-2194 [2019-12-00; online 2019-03-14]
DDLS Fellow Luisa Hugerth
PubMed DOI Crossref
Enhanced translation expands the endo-lysosome size and promotes antigen presentation during phagocyte activation.
Hipolito VEB, Diaz JA, Tandoc KV, ..., Topisirovic I, Botelho RJ
PLoS Biol. 17 (12) e3000535 [2019-12-00; online 2019-12-04]
PubMed DOI Crossref
Comparative Genomics Reveals Shared Mutational Landscape in Canine Hemangiosarcoma and Human Angiosarcoma.
Megquier K, Turner-Maier J, Swofford R, ..., Elvers I, Lindblad-Toh K
Mol. Cancer Res. 17 (12) 2410-2421 [2019-12-00; online 2019-09-30]
PubMed DOI Crossref
Chromatin-sensitive cryptic promoters putatively drive expression of alternative protein isoforms in yeast.
Wei W, Hennig BP, Wang J, ..., Steinmetz LM, Pelechano V
Genome Res 29 (12) 1974-1984 [2019-12-00; online 2019-11-18]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Cardiac expression of the microsomal triglyceride transport protein protects the heart function during ischemia.
Klevstig M, Arif M, Mannila M, ..., Ehrenborg E, Borén J
J. Mol. Cell. Cardiol. 137 (-) 1-8 [2019-12-00; online 2019-09-15]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Biological characterization of new inhibitors of microsomal PGE synthase-1 in preclinical models of inflammation and vascular tone.
Larsson K, Steinmetz J, Bergqvist F, ..., Korotkova M, Jakobsson PJ
Br J Pharmacol 176 (24) 4625-4638 [2019-12-00; online 2019-12-28]
PubMed DOI Crossref
Assessing the potential for assisted gene flow using past introduction of Norway spruce in southern Sweden: Local adaptation and genetic basis of quantitative traits in trees.
Milesi P, Berlin M, Chen J, ..., Karlsson B, Lascoux M
Evol Appl 12 (10) 1946-1959 [2019-12-00; online 2019-08-22]
Pascal Milesi SciLifeLab Fellow
DOI Crossref
Analytic approach to explore dynamical osteoporotic bone turnover
Javed S, Younas M, Bhatti MY, Sohail A, Sattar A
Adv Differ Equ 2019 (1) - [2019-12-00; online 2019-02-14]
PubMed DOI Crossref
Analysis of the Human Protein Atlas Image Classification competition.
Ouyang W, Winsnes CF, Hjelmare M, ..., Kappel C, Lundberg E
Nat. Methods 16 (12) 1254-1261 [2019-12-00; online 2019-11-28]
PubMed DOI Crossref
Absolute Quantification of Apolipoproteins Following Treatment with Omega-3 Carboxylic Acids and Fenofibrate Using a High Precision Stable Isotope-labeled Recombinant Protein Fragments Based SRM Assay.
Hober A, Edfors F, Ryaboshapkina M, ..., Oscarsson J, Miliotis T
Mol. Cell Proteomics 18 (12) 2433-2446 [2019-12-00; online 2019-10-07]
PubMed DOI Crossref
A novel tool for clinical diagnosis of allergy operating a microfluidic immunoaffinity basophil activation test technique.
Aljadi Z, Kalm F, Nilsson C, ..., Lundahl J, Nopp A
Clin. Immunol. 209 (-) 108268 [2019-12-00; online 2019-10-24]
PubMed DOI Crossref
A miR-206 regulated gene landscape enhances mammary epithelial differentiation.
Wang J, Aydoğdu E, Mukhopadhyay S, Helguero LA, Williams C
J. Cell. Physiol. 234 (12) 22220-22233 [2019-12-00; online 2019-05-08]
DOI Crossref
Dissecting chronic myeloid leukaemia overlapping transcriptome with TIF-Seq2
Wang J, Li B, Marques S, ..., Wei W, Pelechano V
- - (-) - [2019-11-29; online 2019-11-29]
PubMed DOI Crossref
Chemical flexibility of heterobimetallic Mn/Fe cofactors: R2lox and R2c proteins.
Kutin Y, Kositzki R, Branca RMM, ..., Cox N, Griese JJ
J Biol Chem 294 (48) 18372-18386 [2019-11-29; online 2019-10-07]
DOI Crossref
The SWI/SNF subunits BRG1 affects alternative splicing by changing RNA binding factor interactions with RNA
Zapater AG, Mackowiak SD, Guo Y, ..., Visa N, Farrants AKÖ
- - (-) - [2019-11-28; online 2019-11-28]
PubMed DOI Crossref
Author Correction: Intra- and inter-individual metabolic profiling highlights carnitine and lysophosphatidylcholine pathways as key molecular defects in type 2 diabetes.
Diamanti K, Cavalli M, Pan G, ..., Komorowski J, Wadelius C
Sci Rep 9 (1) 18158 [2019-11-28; online 2019-11-28]
PubMed DOI Crossref
Local origin or external input: modern horse origin in East Asia.
Ning T, Ling Y, Hu S, ..., Savolainen P, Zhang Y
BMC Evol Biol BMC Evolutionary Biology 19 (1) 217 [2019-11-27; online 2019-11-27]
PubMed DOI Crossref
Increase in negative charge of 68Ga/chelator complex reduces unspecific hepatic uptake but does not improve imaging properties of HER3-targeting affibody molecules.
Rinne SS, Dahlsson Leitao C, Gentry J, ..., Löfblom J, Orlova A
Sci Rep 9 (1) 17710 [2019-11-27; online 2019-11-27]
PubMed DOI Crossref
Helix breaking transition in the S4 of HCN channel is critical for hyperpolarization-dependent gating.
Kasimova MA, Tewari D, Cowgill JB, ..., Delemotte L, Chanda B
Elife 8 (-) - [2019-11-27; online 2019-11-27]
PubMed DOI Crossref
HPV viral load in self-collected vaginal fluid samples as predictor for presence of cervical intraepithelial neoplasia.
Berggrund M, Gustavsson I, Aarnio R, ..., Olovsson M, Gyllensten U
Virol. J. 16 (1) 146 [2019-11-27; online 2019-11-27]
PubMed DOI Crossref
The human secretome.
Uhlén M, Karlsson MJ, Hober A, ..., Fagerberg L, Sivertsson Å
Sci Signal 12 (609) eaaz0274 [2019-11-26; online 2019-11-26]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Evolutionary Refinement of DNA Nanostructures Using Coarse-Grained Molecular Dynamics Simulations.
Benson E, Lolaico M, Tarasov Y, Gådin A, Högberg B
ACS Nano 13 (11) 12591-12598 [2019-11-26; online 2019-10-15]
Erik Benson SciLifeLab Fellow
DOI Crossref
Host-adaptation in Legionellales is 2.4 Ga, coincident with eukaryogenesis
Hugoson E, Ammunét T, Guy L
- - (-) - [2019-11-25; online 2019-11-25]
PubMed DOI Crossref
A genomic survey of transposable elements in the choanoflagellate Salpingoeca rosetta reveals selection on codon usage.
Southworth J, Grace CA, Marron AO, Fatima N, Carr M
Mobile DNA 10 (-) 44 [2019-11-23; online 2019-11-23]
PubMed DOI Crossref
WRNIP1 Protects Reversed DNA Replication Forks from SLX4-Dependent Nucleolytic Cleavage.
Porebski B, Wild S, Kummer S, ..., Gaillard PL, Gari K
iScience 21 (-) 31-41 [2019-11-22; online 2019-10-08]
PubMed DOI Crossref
JNK-Dependent cJun Phosphorylation Mitigates TGFβ- and EGF-Induced Pre-Malignant Breast Cancer Cell Invasion by Suppressing AP-1-Mediated Transcriptional Responses.
Sundqvist A, Voytyuk O, Hamdi M, ..., Ten Dijke P, van Dam H
Cells 8 (12) - [2019-11-21; online 2019-11-21]
PubMed DOI Crossref
Effects of sampling strategy and DNA extraction on human skin microbiome investigations.
Bjerre RD, Hugerth LW, Boulund F, ..., Johansen JD, Engstrand L
Sci Rep 9 (1) 17287 [2019-11-21; online 2019-11-21]
DDLS Fellow Luisa Hugerth
PubMed DOI Crossref
Author Correction: MEG3 long noncoding RNA regulates the TGF-β pathway genes through formation of RNA-DNA triplex structures.
Mondal T, Subhash S, Vaid R, ..., Gorab E, Kanduri C
Nat Commun 10 (1) 5290 [2019-11-21; online 2019-11-21]
DOI Crossref
Reprogrammed mRNA translation drives resistance to therapeutic targeting of ribosome biogenesis
Kusnadi EP, Trigos AS, Cullinane C, ..., Kang J, Pearson RB
- - (-) - [2019-11-20; online 2019-11-20]
PubMed DOI Crossref
Metabolically Active Brown Adipose Tissue Is Found in Adult Subjects with Type 1 Diabetes.
Eriksson O, Selvaraju RK, Berglund M, Espes D
Int J Mol Sci 20 (23) 5827 [2019-11-20; online 2019-11-20]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Inhibition of Upf2-Dependent Nonsense-Mediated Decay Leads to Behavioral and Neurophysiological Abnormalities by Activating the Immune Response.
Johnson JL, Stoica L, Liu Y, ..., Morgan AT, Costa-Mattioli M
Neuron 104 (4) 665-679.e8 [2019-11-20; online 2019-10-01]
PubMed DOI Crossref
Selection of an optimal macrocyclic chelator improves the imaging of prostate cancer using cobalt-labeled GRPR antagonist RM26.
Mitran B, Thisgaard H, Rinne S, ..., Orlova A, Rosenström U
Sci Rep 9 (1) 17086 [2019-11-19; online 2019-11-19]
DOI Crossref
Author response: Helix breaking transition in the S4 of HCN channel is critical for hyperpolarization-dependent gating
Kasimova MA, Tewari D, Cowgill JB, ..., Delemotte L, Chanda B
- - (-) - [2019-11-19; online 2019-11-19]
PubMed DOI Crossref
Training-free measures based on algorithmic probability identify high nucleosome occupancy in DNA sequences.
Zenil H, Minary P
Nucleic Acids Res. 47 (20) e129 [2019-11-18; online 2019-09-13]
PubMed DOI Crossref
Structure of a mitochondrial ATP synthase with bound native cardiolipin.
Mühleip A, McComas SE, Amunts A
Elife 8 (-) - [2019-11-18; online 2019-11-18]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Olfactory Learning in the Stingless Bee Melipona eburnea Friese (Apidae: Meliponini).
Amaya-Márquez M, Tusso S, Hernández J, ..., Wells H, I Abramson C
Insects 10 (11) - [2019-11-18; online 2019-11-18]
DOI Crossref
Human Origins in Southern African Palaeo-wetlands? Strong Claims from Weak Evidence
Schlebusch CM, Loog L, Groucutt HS, ..., Brierley C, Thomas MG
- - (-) - [2019-11-17; online 2019-11-17]
PubMed DOI Crossref
More Favorable Palmitic Acid Over Palmitoleic Acid Modification of Wnt3 Ensures Its Localization and Activity in Plasma Membrane Domains.
Azbazdar Y, Ozalp O, Sezgin E, ..., Karaca E, Ozhan G
Front Cell Dev Biol 7 (-) 281 [2019-11-15; online 2019-11-15]
Erdinc Sezgin SciLifeLab Fellow
DOI Crossref
High-Throughput Functional Ex-Vivo Drug Testing and Multi-Omics Profiling in Patients with Acute Myeloid Leukemia
Erkers T, Seashore-Ludlow B, Struyf N, ..., Lehtiö J, Kallioniemi O
Blood 134 (Supplement_1) 4641-4641 [2019-11-13; online 2019-11-13]
DOI Crossref
GPCRmd uncovers the dynamics of the 3D-GPCRome
Rodríguez-Espigares I, Torrens-Fontanals M, Tiemann JKS, ..., Guixà-González R, Selent J
- - (-) - [2019-11-13; online 2019-11-13]
PubMed DOI Crossref
Impact of γδ T cells on clinical outcome of hematopoietic stem cell transplantation: systematic review and meta-analysis.
Arruda LCM, Gaballa A, Uhlin M
Blood Adv 3 (21) 3436-3448 [2019-11-12; online 2019-11-13]
DOI Crossref
Classification of clear cell renal cell carcinoma based on PKM alternative splicing
Li X, Turanli B, Juszczak K, ..., Zhang C, Mardinoglu A
- - (-) - [2019-11-12; online 2019-11-12]
PubMed DOI Crossref
Early symptoms and sensations as predictors of lung cancer: a machine learning multivariate model.
Levitsky A, Pernemalm M, Bernhardson BM, ..., Tishelman C, Eriksson LE
Sci Rep 9 (1) 16504 [2019-11-11; online 2019-11-11]
PubMed DOI Crossref
Structural basis for the interaction of the chaperone Cbp3 with newly synthesized cytochrome b during mitochondrial respiratory chain assembly.
Ndi M, Masuyer G, Dawitz H, ..., Stenmark P, Ott M
J Biol Chem 294 (45) 16663-16671 [2019-11-08; online 2019-09-19]
PubMed DOI Crossref
RITA requires eIF2α-dependent modulation of mRNA translation for its anti-cancer activity.
Ristau J, van Hoef V, Peuget S, ..., Selivanova G, Larsson O
Cell Death Dis 10 (11) 845 [2019-11-07; online 2019-11-07]
DOI Crossref
NF1 regulates mesenchymal glioblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1
Marques C, Unterkircher T, Kroon P, ..., Carro MS, Squatrito M
- - (-) - [2019-11-07; online 2019-11-07]
PubMed DOI Crossref
Copy number of 8q24.3 drives HSF1 expression and patient outcome in cancer: an individual patient data meta-analysis.
Brusselaers N, Ekwall K, Durand-Dubief M
Hum Genomics 13 (1) 54 [2019-11-07; online 2019-11-07]
PubMed DOI Crossref
Complex I is bypassed during high intensity exercise.
Nilsson A, Björnson E, Flockhart M, Larsen FJ, Nielsen J
Nat Commun 10 (1) 5072 [2019-11-07; online 2019-11-07]
Avlant Nilsson DDLS Fellow
DOI Crossref
Clonally distinct differentiation trajectories shape CD8 + memory T cell heterogeneity after acute viral infections in humans
Mold JE, Modolo L, Hård J, ..., Michaëlsson J, Frisén J
- - (-) - [2019-11-07; online 2019-11-07]
PubMed DOI Crossref
Agonist Selectivity and Ion Permeation in the α3β4 Ganglionic Nicotinic Receptor.
Gharpure A, Teng J, Zhuang Y, ..., Lindahl E, Hibbs RE
Neuron 104 (3) 501-511.e6 [2019-11-06; online 2019-09-02]
PubMed DOI Crossref
Large-Scale Conformational Changes and Protein Function: Breaking the in silico Barrier.
Orellana L
Front Mol Biosci 6 (-) 117 [2019-11-05; online 2019-11-05]
PubMed DOI Crossref
A Systems-Based Map of Human Brain Cell-Type Enriched Genes and Malignancy-Associated Endothelial Changes.
Dusart P, Hallström BM, Renné T, ..., Uhlén M, Butler LM
Cell Reports 29 (6) 1690-1706.e4 [2019-11-05; online 2019-11-07]
PubMed DOI Crossref
Switched reaction specificity in polyesterases towards amide bond hydrolysis by enzyme engineering.
Biundo A, Subagia R, Maurer M, ..., Syrén PO, Guebitz GM
RSC Adv. 9 (62) 36217-36226 [2019-11-04; online 2019-11-07]
PubMed DOI Crossref
ProTstab - predictor for cellular protein stability.
Yang Y, Ding X, Zhu G, ..., Lv Q, Vihinen M
BMC Genomics 20 (1) 804 [2019-11-04; online 2019-11-04]
Abhishek Niroula DDLS Fellow
DOI Crossref
Fibrin fragment E potentiates TGF-β-induced myofibroblast activation and recruitment
Fuchs PF, Heindryckx F, Calitz C, ..., Kreuger J, Gerwins P
- - (-) - [2019-11-04; online 2019-11-04]
PubMed DOI Crossref
Assessment of EGFR gene mutations in circulating free DNA in monitoring of response to EGFR tyrosine kinase inhibitors in patients with lung adenocarcinoma.
Nicoś M, Wojas-Krawczyk K, Krawczyk P, ..., Ramlau R, Milanowski J
Arch Med Sci 16 (6) 1496-1500 [2019-11-03; online 2019-11-03]
PubMed DOI Crossref
eIF4A inhibition circumvents uncontrolled DNA replication mediated by 4E-BP1 loss in pancreatic cancer.
Müller D, Shin S, Goullet de Rugy T, ..., Pyronnet S, Martineau Y
JCI Insight 4 (21) - [2019-11-01; online 2019-11-01]
PubMed DOI Crossref
Isolates from Colonic Spirochetosis in Humans Show High Genomic Divergence and Potential Pathogenic Features but Are Not Detected Using Standard Primers for the Human Microbiota.
Thorell K, Inganäs L, Backhans A, ..., Andreasson A, Engstrand L
J. Bacteriol. 201 (21) - [2019-11-01; online 2019-10-04]
PubMed DOI Crossref
Downregulation of Epidermal Growth Factor Receptor in hepatocellular carcinoma facilitates Transforming Growth Factor-β-induced epithelial to amoeboid transition.
López-Luque J, Bertran E, Crosas-Molist E, ..., Sanz-Moreno V, Fabregat I
Cancer Lett. 464 (-) 15-24 [2019-11-01; online 2019-08-26]
PubMed DOI Crossref
Author Correction: Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells.
Page BDG, Valerie NCK, Wright RHG, ..., Beato M, Helleday T
Nat Commun 10 (1) 5050 [2019-11-01; online 2019-11-01]
PubMed DOI Crossref
Association of Use of the Neonatal Early-Onset Sepsis Calculator With Reduction in Antibiotic Therapy and Safety: A Systematic Review and Meta-analysis.
Achten NB, Klingenberg C, Benitz WE, ..., van Rossum AMC, Plötz FB
JAMA Pediatr 173 (11) 1032-1040 [2019-11-01; online 2019-09-04]
PubMed DOI Crossref
Unraveling African diversity from a cross-disciplinary perspective.
Fortes-Lima C, Mtetwa E, Schlebusch C
Evol Anthropol 28 (6) 288-292 [2019-11-00; online 2019-10-16]
PubMed DOI Crossref
Tissue factor in ulcerative colitis, with and without concomitant primary sclerosing cholangitis.
Vessby J, Lampinen M, Åberg M, ..., Wanders A, Carlson M
Ups. J. Med. Sci. 124 (4) 238-245 [2019-11-00; online 2019-11-27]
PubMed DOI Crossref
Systems biology perspective for studying the gut microbiota in human physiology and liver diseases.
Altay O, Nielsen J, Uhlen M, Boren J, Mardinoglu A
EBioMedicine 49 (-) 364-373 [2019-11-00; online 2019-10-18]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
On-chip background dilution in droplets with high particle recovery using acoustophoresis.
Liu Z, Fornell A, Barbe L, Hjort K, Tenje M
Biomicrofluidics 13 (6) 064123 [2019-11-00; online 2019-12-06]
PubMed DOI Crossref
Novel non-classic CYP21A2 variants, including combined alleles, identified in patients with congenital adrenal hyperplasia.
Karlsson L, de Paula Michelatto D, Lusa ALG, ..., Barbaro M, Lajic S
Clin Biochem 73 (-) 50-56 [2019-11-00; online 2019-07-22]
PubMed DOI Crossref
Molecular imaging mass spectrometry for probing protein dynamics in neurodegenerative disease pathology.
Michno W, Wehrli PM, Blennow K, Zetterberg H, Hanrieder J
J. Neurochem. 151 (4) 488-506 [2019-11-00; online 2018-11-06]
SciLifeLab Fellow Wojciech Michno
PubMed DOI Crossref
Molecular imaging identifies age-related attenuation of acetylcholine in retrosplenial cortex in response to acetylcholinesterase inhibition.
Vallianatou T, Shariatgorji M, Nilsson A, ..., Svenningsson P, Andrén PE
Neuropsychopharmacology 44 (12) 2091-2098 [2019-11-00; online 2019-04-22]
PubMed DOI Crossref
Machine learning and data mining frameworks for predicting drug response in cancer: An overview and a novel in silico screening process based on association rule mining.
Vougas K, Sakellaropoulos T, Kotsinas A, ..., Tsirigos A, Gorgoulis VG
Pharmacol Ther 203 (-) 107395 [2019-11-00; online 2019-07-30]
PubMed DOI Crossref
Higher-order epistasis shapes the fitness landscape of a xenobiotic-degrading enzyme.
Yang G, Anderson DW, Baier F, ..., Bornberg-Bauer E, Tokuriki N
Nat. Chem. Biol. 15 (11) 1120-1128 [2019-11-00; online 2019-10-21]
PubMed DOI Crossref
Functional polymorphisms within the inflammatory pathway regulate expression of extracellular matrix components in a genetic risk dependent model for anterior cruciate ligament injuries.
Suijkerbuijk MAM, Ponzetti M, Rahim M, ..., Collins M, September AV
J Sci Med Sport 22 (11) 1219-1225 [2019-11-00; online 2019-07-29]
PubMed DOI Crossref
Exercise related sudden cardiac death (SCD) in the young - Pre-mortal characterization of a Swedish nationwide cohort, showing a decline in SCD among athletes.
Wisten A, Börjesson M, Krantz P, Stattin EL
Resuscitation 144 (-) 99-105 [2019-11-00; online 2019-09-24]
PubMed DOI Crossref
Evolutionary compaction and adaptation visualized by the structure of the dormant microsporidian ribosome.
Barandun J, Hunziker M, Vossbrinck CR, Klinge S
Nat. Microbiol 4 (11) 1798-1804 [2019-11-00; online 2019-07-22]
Jonas Barandun SciLifeLab Fellow
DOI Crossref
Dual specificity phosphatase (DUSP)-4 is induced by platelet-derived growth factor -BB in an Erk1/2-, STAT3- and p53-dependent manner
Yin R, Eger G, Sarri N, ..., Heldin CH, Lennartsson J
Biochemical and Biophysical Research Communications 519 (3) 469-474 [2019-11-00; online 2019-11-00]
PubMed DOI Crossref
Chemometric Strategies for Sensitive Annotation and Validation of Anatomical Regions of Interest in Complex Imaging Mass Spectrometry Data.
Wehrli PM, Michno W, Blennow K, Zetterberg H, Hanrieder J
J. Am. Soc. Mass Spectrom. 30 (11) 2278-2288 [2019-11-00; online 2019-09-16]
SciLifeLab Fellow Wojciech Michno
PubMed DOI Crossref
CDX2 Loss With Microsatellite Stable Phenotype Predicts Poor Clinical Outcome in Stage II Colorectal Carcinoma.
Slik K, Turkki R, Carpén O, ..., Sundström J, Pellinen T
Am J Surg Pathol 43 (11) 1473-1482 [2019-11-00; online 2019-09-07]
PubMed DOI Crossref
Building gene regulatory networks from scATAC-seq and scRNA-seq using Linked Self Organizing Maps.
Jansen C, Ramirez RN, El-Ali NC, ..., Conesa A, Mortazavi A
PLoS Comput Biol 15 (11) e1006555 [2019-11-00; online 2019-11-04]
PubMed DOI Crossref
Autism needs to be considered in children with Down Syndrome.
Wester Oxelgren U, Åberg M, Myrelid Å, ..., Gustafsson J, Fernell E
Acta Paediatr 108 (11) 2019-2026 [2019-11-00; online 2019-06-09]
PubMed DOI Crossref
Author Correction: Leveraging European infrastructures to access 1 million human genomes by 2022.
Saunders G, Baudis M, Becker R, ..., Blomberg N, Scollen S
Nat. Rev. Genet. 20 (11) 702 [2019-11-00; online 2019-09-15]
PubMed DOI Crossref
Astakine1 forms protein complex in plasma.
Sirikharin R, Noonin C, Junkunlo K, Söderhäll K, Söderhäll I
Fish Shellfish Immunol. 94 (-) 66-71 [2019-11-00; online 2019-08-26]
PubMed DOI Crossref
Association of PTHrP levels in CSF with Alzheimer's disease biomarkers.
Kushnir MM, Michno W, Rockwood AL, ..., Strathmann FG, Hanrieder J
Clin Mass Spectrom 14 Pt B (-) 124-129 [2019-11-00; online 2018-10-09]
SciLifeLab Fellow Wojciech Michno
PubMed DOI Crossref
Apis mellifera.
Webster MT
Trends in Genetics 35 (11) 880-881 [2019-11-00; online 2019-10-09]
PubMed DOI Crossref
ADAMDEC1 Maintains a Growth Factor Signaling Loop in Cancer Stem Cells.
Jimenez-Pascual A, Hale JS, Kordowski A, ..., Lathia JD, Siebzehnrubl FA
Cancer Discov 9 (11) 1574-1589 [2019-11-00; online 2019-08-21]
PubMed DOI Crossref
14-3-3 scaffold proteins mediate the inactivation of trim25 and inhibition of the type I interferon response by herpesvirus deconjugases.
Gupta S, Ylä-Anttila P, Sandalova T, ..., Achour A, Masucci MG
PLoS Pathog 15 (11) e1008146 [2019-11-00; online 2019-11-11]
PubMed DOI Crossref
The role of ligand-gated conformational changes in enzyme catalysis.
Moreira C, Calixto AR, Richard JP, Kamerlin SCL
Biochem. Soc. Trans. 47 (5) 1449-1460 [2019-10-31; online 2019-10-28]
PubMed DOI Crossref
STATegra, a comprehensive multi-omics dataset of B-cell differentiation in mouse.
Gomez-Cabrero D, Tarazona S, Ferreirós-Vidal I, ..., Tegner J, Conesa A
Sci Data 6 (1) 256 [2019-10-31; online 2019-10-31]
DOI Crossref
Pooled CRISPRi screening of the cyanobacterium Synechocystis sp. PCC 6803 for enhanced growth, tolerance, and chemical production
Yao L, Shabestary K, Björk SM, ..., Jahn M, Hudson EP
- - (-) - [2019-10-30; online 2019-10-30]
PubMed DOI Crossref
Population structure of drug-resistant Mycobacterium tuberculosis in Central Asia.
Engström A, Antonenka U, Kadyrov A, ..., Niemann S, Hoffmann H
BMC Infect Dis 19 (1) 908 [2019-10-29; online 2019-10-29]
PubMed DOI Crossref
Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9.
Schmidt AF, Holmes MV, Preiss D, ..., Casas JP, Hingorani AD
BMC Cardiovasc Disord 19 (1) 240 [2019-10-29; online 2019-10-29]
DOI Crossref
Transcript isoform sequencing reveals widespread promoter-proximal transcriptional termination
Ard R, Thomas Q, Li B, ..., Pelechano V, Marquardt S
- - (-) - [2019-10-28; online 2019-10-28]
PubMed DOI Crossref
Sharing Data from Molecular Simulations.
Abraham M, Apostolov R, Barnoud J, ..., Woods C, Zhmurov A
J Chem Inf Model 59 (10) 4093-4099 [2019-10-28; online 2019-10-11]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Domainoid: domain-oriented orthology inference.
Persson E, Kaduk M, Forslund SK, Sonnhammer ELL
BMC Bioinformatics 20 (1) 523 [2019-10-28; online 2019-10-28]
DOI Crossref
Liver X Receptor regulates Th17 and RORγt + Treg cells by distinct mechanisms
Parigi SM, Das S, Frede A, ..., Gustafsson JÅ, Villablanca EJ
- - (-) - [2019-10-25; online 2019-10-25]
DOI Crossref
In Silico Druggability Assessment of the NUDIX Hydrolase Protein Family as a Workflow for Target Prioritization
Michel M, Homan EJ, Wiita E, ..., Helleday T, Berglund UW
- - (-) - [2019-10-25; online 2019-10-25]
DOI Crossref
In Silico Druggability Assessment of the NUDIX Hydrolase Protein Family as a Workflow for Target Prioritization
Michel M, Homan EJ, Wiita E, ..., Helleday T, Berglund UW
- - (-) - [2019-10-25; online 2019-10-25]
PubMed DOI Crossref
Detection of a High-Turnover Serotonin Circuit in the Mouse Brain Using Mass Spectrometry Imaging.
Sugiyama E, Guerrini MM, Honda K, ..., Suematsu M, Sugiura Y
iScience 20 (-) 359-372 [2019-10-25; online 2019-09-27]
PubMed DOI Crossref
ClinGen Myeloid Malignancy Variant Curation Expert Panel recommendations for germline RUNX1 variants.
Luo X, Feurstein S, Mohan S, ..., Wu D, Godley LA
Blood Adv 3 (20) 2962-2979 [2019-10-22; online 2019-10-28]
DOI Crossref
Genome Sequence of Segmented Filamentous Bacteria Present in the Human Intestine
Jonsson H, Hugerth LW, Sundh J, Andersson AF
- - (-) - [2019-10-21; online 2019-10-21]
PubMed DOI Crossref
The importance of study design in the application of artificial intelligence methods in medicine.
Eklund M, Kartasalo K, Olsson H, Ström P
NPJ Digit Med 2 (-) 101 [2019-10-18; online 2019-10-18]
DDLS Fellow Kimmo Kartasalo
PubMed DOI Crossref
Phagocytosis is mediated by two-dimensional assemblies of the F-BAR protein GAS7.
Hanawa-Suetsugu K, Itoh Y, Ab Fatah M, ..., Shimada A, Suetsugu S
Nat Commun 10 (1) 4763 [2019-10-18; online 2019-10-18]
PubMed DOI Crossref
CUTseq is a versatile method for preparing multiplexed DNA sequencing libraries from low-input samples.
Zhang X, Garnerone S, Simonetti M, ..., Bienko M, Crosetto N
Nat Commun 10 (1) 4732 [2019-10-18; online 2019-10-18]
Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
Assessment of glucagon receptor occupancy by Positron Emission Tomography in non-human primates.
Eriksson O, Velikyan I, Haack T, ..., Pierrou S, Wagner M
Sci Rep 9 (1) 14960 [2019-10-18; online 2019-10-18]
Olof Eriksson SciLifeLab Fellow
DOI Crossref
Accurate contact-based modelling of repeat proteins predicts the structure of Curlin and SPW repeats
Bassot C, Elofsson A
- - (-) - [2019-10-17; online 2019-10-17]
PubMed DOI Crossref
Prenatal maternal and childhood bisphenol a exposure and brain structure and behavior of young children.
Grohs MN, Reynolds JE, Liu J, ..., Dewey D, APrON Study Team
Environ Health 18 (1) 85 [2019-10-15; online 2019-10-15]
PubMed DOI Crossref
Dual Bioorthogonal Labeling of the Amyloid-β Protein Precursor Facilitates Simultaneous Visualization of the Protein and Its Cleavage Products.
van Husen LS, Schedin-Weiss S, Trung MN, ..., Elsässer SJ, Tjernberg LO
J. Alzheimers Dis. 72 (2) 537-548 [2019-10-15; online 2019-10-15]
PubMed DOI Crossref
CSF levels of apolipoprotein C1 and autotaxin found to associate with neuropathic pain and fibromyalgia.
Lind AL, Just D, Mikus M, ..., Gordh T, Månberg A
J Pain Res 12 (-) 2875-2889 [2019-10-15; online 2019-10-15]
PubMed DOI Crossref
Author Correction: Extracellular nanovesicles released from the commensal yeast Malassezia sympodialis are enriched in allergens and interact with cells in human skin.
Johansson HJ, Vallhov H, Holm T, ..., Lehtiö J, Scheynius A
Sci Rep 9 (1) 15014 [2019-10-15; online 2019-10-15]
PubMed DOI Crossref
An intrinsically disordered proteins community for ELIXIR.
Davey NE, Babu MM, Blackledge M, ..., Wichapong K, Tosatto SCE
F1000Res 8 (-) - [2019-10-15; online 2019-10-15]
PubMed DOI Crossref
Activation of Oncogenic Super-Enhancers Is Coupled with DNA Repair by RAD51.
Hazan I, Monin J, Bouwman BAM, Crosetto N, Aqeilan RI
Cell Reports 29 (3) 560-572.e4 [2019-10-15; online 2019-10-17]
PubMed DOI Crossref
A Fluorescent Kinase Inhibitor that Exhibits Diagnostic Changes in Emission upon Binding.
Fleming CL, Sandoz PA, Inghardt T, ..., Grøtli M, Andréasson J
Angew. Chem. Int. Ed. Engl. 58 (42) 15000-15004 [2019-10-14; online 2019-09-05]
DOI Crossref
A Fluorescent Kinase Inhibitor that Exhibits Diagnostic Changes in Emission upon Binding
Fleming CL, Sandoz PA, Inghardt T, ..., Grøtli M, Andréasson J
Angewandte Chemie 131 (42) 15142-15146 [2019-10-14; online 2019-09-05]
PubMed DOI Crossref
A Fluorescence-based Assay for Characterization and Quantification of Lipid Droplet Formation in Human Intestinal Organoids.
van Rijn JM, van Hoesel M, Middendorp S
J Vis Exp - (152) - [2019-10-13; online 2019-10-13]
PubMed DOI Crossref
Characterization of transgenic mouse models targeting neuromodulatory systems reveals organizational principles of the dorsal raphe.
Cardozo Pinto DF, Yang H, Pollak Dorocic I, ..., Smidt MP, Lammel S
Nat Commun 10 (1) 4633 [2019-10-11; online 2019-10-11]
Iskra Pollak Dorocic SciLifeLab Fellow
PubMed DOI Crossref
N-Trifluoromethylthiolated Sulfonimidamides and Sulfoximines: Anti-microbial, Anti-mycobacterial, and Cytotoxic Activity.
Thota N, Makam P, Rajbongshi KK, ..., Naicker T, Arvidsson PI
ACS Med. Chem. Lett. 10 (10) 1457-1461 [2019-10-10; online 2019-09-11]
PubMed DOI Crossref
Uncovering the Role of Key Active-Site Side Chains in Catalysis: An Extended Brønsted Relationship for Substrate Deprotonation Catalyzed by Wild-Type and Variants of Triosephosphate Isomerase.
Kulkarni YS, Amyes TL, Richard JP, Kamerlin SCL
Journal of the American Chemical Society 141 (40) 16139-16150 [2019-10-09; online 2019-09-25]
DOI Crossref
MetaCNV - a consensus approach to infer accurate copy numbers from low coverage data
Friedrich S, Barbulescu R, Helleday T, Sonnhammer EL
- - (-) - [2019-10-07; online 2019-10-07]
PubMed DOI Crossref
Remodeling the genome with DNA twists.
Bowman GD, Deindl S
Science (New York, N.Y.) 366 (6461) 35-36 [2019-10-04; online 2019-10-12]
SciLifeLab Fellow Sebastian Deindl
DOI Crossref
Ecosystem responses to increased organic carbon concentration: comparing results based on long-term monitoring and whole-lake experimentation
Kankaala P, Arvola L, Hiltunen M, ..., Tulonen T, Vesala S
Inland Waters 9 (4) 489-502 [2019-10-02; online 2019-07-30]
DOI Crossref
Tiled STED Imaging of Extended Sample Regions
Alvelid J, Testa I
- - (-) - [2019-10-01; online 2019-10-01]
DOI Crossref
P764A quality improvement program for heart failure involving structured patient data, diagnosis and organization of care - results from the 4D heart failure project
Matan D, Lofstrom U, Cabrera-Corovic C, ..., Linde C, Persson H
Eur. Heart J. 40 (Supplement_1) - [2019-10-01; online 2019-10-21]
PubMed DOI Crossref
Industrial wastewater treatment plant enriches antibiotic resistance genes and alters the structure of microbial communities.
Bengtsson-Palme J, Milakovic M, Švecová H, ..., Grabic R, Udikovic-Kolic N
Water Res 162 (-) 437-445 [2019-10-01; online 2019-07-04]
DDLS Fellow Johan Bengtsson-Palme
PubMed DOI Crossref
Dysregulation of the Tryptophan Pathway Evidences Gender Differences in COPD.
Naz S, Bhat M, Ståhl S, ..., Wheelock ÅM, Wheelock CE
Metabolites 9 (10) - [2019-10-01; online 2019-10-01]
PubMed DOI Crossref
Advances and Applications in the Quest for Orthologs.
Glover N, Dessimoz C, Ebersberger I, ..., Sonnhammer E, Thomas PD
Mol. Biol. Evol. 36 (10) 2157-2164 [2019-10-01; online 2019-06-27]
DOI Crossref
217Metabolomic profile of patients with new onset heart failure; more microvascular dysfunction in patients with preserved ejection fraction compared to reduced ejection fraction - the PREFERS Study
Hage C, Lofgren L, Michopoulos F, ..., Persson H, Linde C
Eur. Heart J. 40 (Supplement_1) - [2019-10-01; online 2019-10-21]
PubMed DOI Crossref
Voices in methods development.
Anikeeva P, Boyden E, Brangwynne C, ..., Zernicka-Goetz M, Zhuang X
Nat. Methods 16 (10) 945-951 [2019-10-00; online 2019-09-29]
PubMed DOI Crossref
VGLUT2 rs2290045 genotype moderates environmental sensitivity to alcohol-related problems in three samples of youths.
Vrettou M, Nilsson KW, Tuvblad C, ..., Nylander I, Comasco E
Eur Child Adolesc Psychiatry 28 (10) 1329-1340 [2019-10-00; online 2019-02-25]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Understanding the Influence of Nanocarrier-Mediated Brain Delivery on Therapeutic Performance Through Pharmacokinetic-Pharmacodynamic Modeling.
Hu Y, Hammarlund-Udenaes M, Fridén M
J Pharm Sci 108 (10) 3425-3433 [2019-10-00; online 2019-06-01]
PubMed DOI Crossref
T-cell frequencies of CD8+ γδ and CD27+ γδ cells in the stem cell graft predict the outcome after allogeneic hematopoietic cell transplantation.
Gaballa A, Stikvoort A, Önfelt B, ..., Watz E, Uhlin M
Bone Marrow Transplant 54 (10) 1562-1574 [2019-10-00; online 2019-02-05]
PubMed DOI Crossref
Regulation of adenylyl cyclase 5 in striatal neurons confers the ability to detect coincident neuromodulatory signals.
Bruce NJ, Narzi D, Trpevski D, ..., Carloni P, Hellgren Kotaleski J
PLoS Comput Biol 15 (10) e1007382 [2019-10-00; online 2019-10-30]
PubMed DOI Crossref
Proteomics identifies neddylation as a potential therapy target in small intestinal neuroendocrine tumors.
Fotouhi O, Kjellin H, Juhlin CC, ..., Larsson C, Orre LM
Oncogene 38 (43) 6881-6897 [2019-10-00; online 2019-08-12]
PubMed DOI Crossref
Pancreatic perfusion and its response to glucose as measured by simultaneous PET/MRI.
Espes D, Manell E, Rydén A, ..., Jansson L, Eriksson O
Acta diabetologica 56 (10) 1113-1120 [2019-10-00; online 2019-04-26]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Inhibition of SYK or BTK augments venetoclax sensitivity in SHP1-negative/BCL-2-positive diffuse large B-cell lymphoma.
Sasi BK, Martines C, Xerxa E, ..., Rosenquist R, Efremov DG
Leukemia 33 (10) 2416-2428 [2019-10-00; online 2019-03-14]
PubMed DOI Crossref
High-definition spatial transcriptomics for in situ tissue profiling.
Vickovic S, Eraslan G, Salmén F, ..., Regev A, Ståhl PL
Nat. Methods 16 (10) 987-990 [2019-10-00; online 2019-09-09]
Sanja Vickovic SciLifeLab Fellow
PubMed DOI Crossref
High-Fat Diet Enriched with Bilberry Modifies Colonic Mucus Dynamics and Restores Marked Alterations of Gut Microbiome in Rats.
Liu HY, Walden TB, Ahl D, ..., Phillipson M, Holm L
Mol Nutr Food Res 63 (20) e1900117 [2019-10-00; online 2019-08-12]
PubMed DOI Crossref
Genetic basis and timing of a major mating system shift in Capsella.
Bachmann JA, Tedder A, Laenen B, ..., Castric V, Slotte T
New Phytol. 224 (1) 505-517 [2019-10-00; online 2019-08-01]
SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Dynamic membrane topology in an unassembled membrane protein.
Seurig M, Ek M, von Heijne G, Fluman N
Nat. Chem. Biol. 15 (10) 945-948 [2019-10-00; online 2019-09-09]
PubMed DOI Crossref
Duration of use of proton pump inhibitors and the risk of gastric and oesophageal cancer.
Brusselaers N, Lagergren J, Engstrand L
Cancer Epidemiol 62 (-) 101585 [2019-10-00; online 2019-08-21]
PubMed DOI Crossref
Dog Ownership and Survival After a Major Cardiovascular Event: A Register-Based Prospective Study.
Mubanga M, Byberg L, Egenvall A, Ingelsson E, Fall T
Circ Cardiovasc Qual Outcomes 12 (10) e005342 [2019-10-00; online 2019-10-08]
PubMed DOI Crossref
Diversity and evolution of chitin synthases in oomycetes (Straminipila: Oomycota).
Klinter S, Bulone V, Arvestad L
Mol. Phylogenet. Evol. 139 (-) 106558 [2019-10-00; online 2019-07-06]
PubMed DOI Crossref
Disulfiram's anti-cancer activity reflects targeting NPL4, not inhibition of aldehyde dehydrogenase.
Skrott Z, Majera D, Gursky J, ..., Mistrik M, Bartek J
Oncogene 38 (40) 6711-6722 [2019-10-00; online 2019-08-07]
PubMed DOI Crossref
Detecting sequence signals in targeting peptides using deep learning.
Almagro Armenteros JJ, Salvatore M, Emanuelsson O, ..., Elofsson A, Nielsen H
Life Sci. Alliance 2 (5) - [2019-10-00; online 2019-09-30]
PubMed DOI Crossref
Concomitant Ro/SSA and La/SSB antibodies are biomarkers for the risk of venous thromboembolism and cerebral infarction in primary Sjögren's syndrome.
Mofors J, Holmqvist M, Westermark L, ..., Wahren-Herlenius M, Nordmark G
J. Intern. Med. 286 (4) 458-468 [2019-10-00; online 2019-06-17]
PubMed DOI Crossref
Comprehensive mapping of neurotransmitter networks by MALDI-MS imaging.
Shariatgorji M, Nilsson A, Fridjonsdottir E, ..., Odell LR, Andrén PE
Nat. Methods 16 (10) 1021-1028 [2019-10-00; online 2019-09-23]
PubMed DOI Crossref
Association between Transcription Factor AP-2B genotype, obesity, insulin resistance and dietary intake in a longitudinal birth cohort study.
Joost U, Villa I, Comasco E, ..., Veidebaum T, Harro J
Int J Obes (Lond) 43 (10) 2095-2106 [2019-10-00; online 2019-06-17]
Erika Comasco SciLifeLab Fellow
DOI Crossref
An Empirical Study of the Relation Between Network Architecture and Complexity
Konuk E, Smith K
- - (-) 4597-4599 [2019-10-00; online 2019-10-00]
PubMed DOI Crossref
Acute Cocaine Enhances Dopamine D2R Recognition and Signaling and Counteracts D2R Internalization in Sigma1R-D2R Heteroreceptor Complexes.
Borroto-Escuela DO, Narváez M, Romero-Fernández W, ..., Ferraro L, Fuxe K
Mol. Neurobiol. 56 (10) 7045-7055 [2019-10-00; online 2019-04-10]
PubMed DOI Crossref
A way forward with eco evo devo: an extended theory of resource polymorphism with postglacial fishes as model systems.
Skúlason S, Parsons KJ, Svanbäck R, ..., Smith C, Snorrason SS
Biol Rev Camb Philos Soc 94 (5) 1786-1808 [2019-10-00; online 2019-06-19]
PubMed DOI Crossref
A natural toroidal microswimmer with a rotary eukaryotic flagellum.
Hess S, Eme L, Roger AJ, Simpson AGB
Nat. Microbiol 4 (10) 1620-1626 [2019-10-00; online 2019-06-10]
DOI Crossref
Interactions between Toll-Like Receptor 4 (TLR4) polymorphisms and urban or rural living on the risk for Asthma
Kisiel M, Rask-Andersen M, Johansson Å, Ek W, Rask-Andersen A
- - (-) PA1977 [2019-09-28; online 2019-11-21]
PubMed DOI Crossref
Warburg and Krebs and related effects in cancer.
Unterlass JE, Curtin NJ
Expert Rev Mol Med 21 (-) e4 [2019-09-27; online 2019-09-27]
DOI Crossref
Molecular Atlas of the Adult Mouse Brain
Ortiz C, Navarro JF, Jurek A, ..., Lundeberg J, Meletis K
- - (-) - [2019-09-27; online 2019-09-27]
PubMed DOI Crossref
Homogeneous Differential Magnetic Assay.
Sepehri S, Zardán Gómez de la Torre T, Schneiderman JF, ..., Winkler D, Kalaboukhov A
ACS Sens 4 (9) 2381-2388 [2019-09-27; online 2019-08-22]
PubMed DOI Crossref
EvoChromo: towards a synthesis of chromatin biology and evolution.
Drinnenberg IA, Berger F, Elsässer SJ, ..., Warnecke T, Wolfe KH
Development 146 (19) - [2019-09-26; online 2019-09-26]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Cytoplasmic protein misfolding titrates Hsp70 to activate nuclear Hsf1.
Masser AE, Kang W, Roy J, ..., Friedländer MR, Andréasson C
Elife 8 (-) - [2019-09-25; online 2019-09-25]
DOI Crossref
Multi-HLA class II tetramer analyses of citrulline-reactive T cells and early treatment response in rheumatoid arthritis
Gerstner C, Turcinov S, Hensvold AH, ..., Baarsen LGMv, Malmström V
- - (-) - [2019-09-24; online 2019-09-24]
PubMed DOI Crossref
Identification and Characterization of Post-activated B Cells in Systemic Autoimmune Diseases.
Weißenberg SY, Szelinski F, Schrezenmeier E, ..., Lino AC, Dörner T
Front Immunol 10 (-) 2136 [2019-09-24; online 2019-09-24]
PubMed DOI Crossref
Chromatin conformation remains stable upon extensive transcriptional changes driven by heat shock.
Ray J, Munn PR, Vihervaara A, ..., Danko CG, Lis JT
Proc. Natl. Acad. Sci. U.S.A. 116 (39) 19431-19439 [2019-09-24; online 2019-09-10]
Anniina Vihervaara SciLifeLab Fellow
DOI Crossref
Faculty Opinions recommendation of The nucleosome core particle remembers its position through DNA replication and RNA transcription.
Elsässer S
- - (-) - [2019-09-23; online 2019-09-17]
PubMed DOI Crossref
What industry can teach academia.
Mao Y
Science (New York, N.Y.) 365 (6459) 1342 [2019-09-20; online 2019-10-12]
SciLifeLab Fellow Yumeng Mao
PubMed DOI Crossref
The Complement System Is Essential for the Phagocytosis of Mesenchymal Stromal Cells by Monocytes.
Gavin C, Meinke S, Heldring N, ..., Le Blanc K, Kadri N
Front Immunol 10 (-) 2249 [2019-09-20; online 2019-09-20]
PubMed DOI Crossref
The Stapled Peptide PM2 Stabilizes p53 Levels and Radiosensitizes Wild-Type p53 Cancer Cells.
Mortensen ACL, Spiegelberg D, Brown CJ, Lane DP, Nestor M
Front Oncol 9 (-) 923 [2019-09-19; online 2019-09-19]
DOI Crossref
Identification of spatial compartments in tissue from in situ sequencing data
Partel G, Hilscher MM, Milli G, ..., Nilsson M, Wählby C
- - (-) - [2019-09-18; online 2019-09-18]
PubMed DOI Crossref
Quantitative Multiplexed ChIP Reveals Global Alterations that Shape Promoter Bivalency in Ground State Embryonic Stem Cells.
Kumar B, Elsässer SJ
Cell Reports 28 (12) 3274-3284.e5 [2019-09-17; online 2019-09-19]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Characterization of Binding of Magnetic Nanoparticles to Rolling Circle Amplification Products by Turn-On Magnetic Assay.
Sepehri S, Agnarsson B, Torre TZG, ..., Winkler D, Kalaboukhov A
Biosensors (Basel) 9 (3) - [2019-09-17; online 2019-09-17]
DOI Crossref
Nuclear gene proximity and protein interactions shape transcript covariances in mammalian single cells
Tarbier M, Mackowiak SD, Frade J, ..., Gallant CJ, Friedländer MR
- - (-) - [2019-09-16; online 2019-09-16]
PubMed DOI Crossref
eBDIMS server: protein transition pathways with ensemble analysis in 2D-motion spaces.
Orellana L, Gustavsson J, Bergh C, Yoluk O, Lindahl E
Bioinformatics 35 (18) 3505-3507 [2019-09-15; online 2019-03-07]
PubMed DOI Crossref
Heparanase promotes glioma progression via enhancing CD24 expression.
Barash U, Spyrou A, Liu P, ..., Vlodavsky I, Yang X
Int. J. Cancer 145 (6) 1596-1608 [2019-09-15; online 2019-05-14]
PubMed DOI Crossref
Batch-normalization of cerebellar and medulloblastoma gene expression datasets utilizing empirically defined negative control genes.
Weishaupt H, Johansson P, Sundström A, ..., Nelander S, Swartling FJ
Bioinformatics 35 (18) 3357-3364 [2019-09-15; online 2019-02-05]
PubMed DOI Crossref
Bispecific GRPR-Antagonistic Anti-PSMA/GRPR Heterodimer for PET and SPECT Diagnostic Imaging of Prostate Cancer.
Mitran B, Varasteh Z, Abouzayed A, ..., Orlova A, Rosenström U
Cancers (Basel) 11 (9) - [2019-09-14; online 2019-09-14]
PubMed DOI Crossref
Mechanical properties of plasma membrane vesicles correlate with lipid order, viscosity and cell density.
Steinkühler J, Sezgin E, Urbančič I, Eggeling C, Dimova R
Commun Biol 2 (-) 337 [2019-09-13; online 2019-09-13]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Medicine and the media: Medical experts' problems and solutions while working with journalists.
Larsson A, Appel S, Sundberg CJ, Rosenqvist M
PLoS ONE 14 (9) e0220897 [2019-09-12; online 2019-09-12]
PubMed DOI Crossref
Chlamydia pan-genomic analysis reveals balance between host adaptation and selective pressure to genome reduction.
Sigalova OM, Chaplin AV, Bochkareva OO, ..., Burskaia V, Gelfand MS
BMC Genomics 20 (1) 710 [2019-09-12; online 2019-09-12]
PubMed DOI Crossref
Autoantibodies to Killer Cell Immunoglobulin-Like Receptors in Patients With Systemic Lupus Erythematosus Induce Natural Killer Cell Hyporesponsiveness.
Segerberg F, Lundtoft C, Reid S, ..., Carlsten M, Hagberg N
Front Immunol 10 (-) 2164 [2019-09-11; online 2019-09-11]
PubMed DOI Crossref
Perturbation of mitochondrial bioenergetics by polycations counteracts resistance to BRAFE600 inhibition in melanoma cells.
Hall A, Maynard S, Wu LP, ..., Moghimi SM, Bartek J
J Control Release 309 (-) 158-172 [2019-09-10; online 2019-07-23]
PubMed DOI Crossref
Peptide-Induced Lipid Flip-Flop in Asymmetric Liposomes Measured by Small Angle Neutron Scattering.
Nguyen MHL, DiPasquale M, Rickeard BW, ..., Katsaras J, Marquardt D
Langmuir 35 (36) 11735-11744 [2019-09-10; online 2019-08-27]
DDLS Fellow Milka Doktorova
DOI Crossref
Strategies to Reduce or Eliminate Resistant Pathogens in the Environment
Bengtsson‐Palme J, Heß S
Antibiotic Drug Resistance - (-) 637-673 [2019-09-09; online 2019-08-23]
DDLS Fellow Johan Bengtsson-Palme
DOI Crossref
Sharing Data from Molecular Simulations
Abraham MJ, Apostolov R, Barnoud J, ..., Woods C, Zhmurov A
- - (-) - [2019-09-09; online 2019-09-09]
DOI Crossref
Sharing Data from Molecular Simulations
Abraham MJ, Apostolov R, Barnoud J, ..., Woods C, Zhmurov A
- - (-) - [2019-09-09; online 2019-09-09]
PubMed DOI Crossref
Comprehensive investigation of key biomarkers and pathways in hepatitis B virus-related hepatocellular carcinoma.
Liao X, Yu T, Yang C, ..., Ye X, Peng T
J. Cancer 10 (23) 5689-5704 [2019-09-07; online 2019-09-07]
PubMed DOI Crossref
Speeding Up Percolator.
Halloran JT, Zhang H, Kara K, ..., Käll L, Noble WS
J. Proteome Res. 18 (9) 3353-3359 [2019-09-06; online 2019-08-23]
PubMed DOI Crossref
Identification of a Biomarker Panel for Early Detection of Lung Cancer Patients.
Geary B, Walker MJ, Snow JT, ..., Crosbie PA, Whetton AD
J. Proteome Res. 18 (9) 3369-3382 [2019-09-06; online 2019-08-21]
DOI Crossref
Splotch: Robust estimation of aligned spatial temporal gene expression data
Äijö T, Maniatis S, Vickovic S, ..., Lundeberg J, Bonneau R
- - (-) - [2019-09-05; online 2019-09-05]
PubMed DOI Crossref
Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis.
Huang M, Tailor J, Zhen Q, ..., Smith A, Weiss WA
Cell Stem Cell 25 (3) 433-446.e7 [2019-09-05; online 2019-06-13]
PubMed DOI Crossref
Double-strand breaks in ribosomal RNA genes activate a distinct signaling and chromatin response to facilitate nucleolar restructuring and repair.
Korsholm LM, Gál Z, Lin L, ..., Bartek J, Larsen DH
Nucleic Acids Res. 47 (15) 8019-8035 [2019-09-05; online 2019-06-12]
DOI Crossref
Mumame: a software tool for quantifying gene-specific point-mutations in shotgun metagenomic data
Magesh S, Jonsson V, Bengtsson-Palme J
MBMG 3 (-) - [2019-09-04; online 2019-09-04]
DDLS Fellow Johan Bengtsson-Palme
PubMed DOI Crossref
Insights Into Enhanced Complement Activation by Structures of Properdin and Its Complex With the C-Terminal Domain of C3b.
van den Bos RM, Pearce NM, Granneman J, Brondijk THC, Gros P
Front Immunol 10 (-) 2097 [2019-09-04; online 2019-09-04]
DDLS Fellow Nicholas Pearce
PubMed DOI Crossref
Unveiling the Biochemistry of the Epigenetic Regulator SMYD3.
Fabini E, Talibov VO, Mihalic F, ..., Del Rio A, Danielson UH
Biochemistry 58 (35) 3634-3645 [2019-09-03; online 2019-08-21]
PubMed DOI Crossref
Meiotic sex in Chagas disease parasite Trypanosoma cruzi.
Schwabl P, Imamura H, Van den Broeck F, ..., Grijalva MJ, Llewellyn MS
Nat Commun 10 (1) 3972 [2019-09-03; online 2019-09-03]
DOI Crossref
Author response: Cytoplasmic protein misfolding titrates Hsp70 to activate nuclear Hsf1
Masser AE, Kang W, Roy J, ..., Friedländer MR, Andréasson C
- - (-) - [2019-09-03; online 2019-09-03]
PubMed DOI Crossref
NK cells switch from granzyme B to death receptor-mediated cytotoxicity during serial killing.
Prager I, Liesche C, van Ooijen H, ..., Önfelt B, Watzl C
J. Exp. Med. 216 (9) 2113-2127 [2019-09-02; online 2019-07-03]
DOI Crossref
Integrated thin film resistive sensors for in situ temperature measurements in an acoustic trap
Werr G, Khaji Z, Ohlin M, ..., Hjort K, Tenje M
J. Micromech. Microeng. 29 (9) 095003 [2019-09-01; online 2019-07-01]
PubMed DOI Crossref
Impact of Epithelial-Stromal Interactions on Peritumoral Fibroblasts in Ductal Carcinoma in Situ.
Strell C, Paulsson J, Jin SB, ..., Wärnberg F, Östman A
J. Natl. Cancer Inst. 111 (9) 983-995 [2019-09-01; online 2019-03-01]
PubMed DOI Crossref
The majority of Swedish systemic lupus erythematosus patients are still affected by irreversible organ impairment: factors related to damage accrual in two regional cohorts.
Frodlund M, Reid S, Wetterö J, ..., Sjöwall C, Leonard D
Lupus 28 (10) 1261-1272 [2019-09-00; online 2019-07-11]
PubMed DOI Crossref
Streptococcal sagA activates a proinflammatory response in mast cells by a sublytic mechanism.
von Beek C, Waern I, Eriksson J, ..., Guss B, Pejler G
Cell. Microbiol. 21 (9) e13064 [2019-09-00; online 2019-07-07]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Salmonella persisters promote the spread of antibiotic resistance plasmids in the gut.
Bakkeren E, Huisman JS, Fattinger SA, ..., Diard M, Hardt WD
Nature 573 (7773) 276-280 [2019-09-00; online 2019-09-04]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Regulation of replication fork speed: Mechanisms and impact on genomic stability.
Merchut-Maya JM, Bartek J, Maya-Mendoza A
DNA Repair (Amst.) 81 (-) 102654 [2019-09-00; online 2019-07-08]
PubMed DOI Crossref
Real-time prediction of influenza outbreaks in Belgium.
Miranda GHB, Baetens JM, Bossuyt N, Bruno OM, De Baets B
Epidemics 28 (-) 100341 [2019-09-00; online 2019-04-18]
Gisele Miranda SciLifeLab Fellow
PubMed DOI Crossref
Rate and extent of mitragynine and 7-hydroxymitragynine blood-brain barrier transport and their intra-brain distribution: the missing link in pharmacodynamic studies.
Yusof SR, Mohd Uzid M, Teh EH, ..., Loryan I, Hammarlund-Udenaes M
Addict Biol 24 (5) 935-945 [2019-09-00; online 2018-08-08]
PubMed DOI Crossref
Ouabain-regulated phosphoproteome reveals molecular mechanisms for Na+, K+-ATPase control of cell adhesion, proliferation, and survival.
Panizza E, Zhang L, Fontana JM, ..., Lehtiö J, Aperia A
FASEB J. 33 (9) 10193-10206 [2019-09-00; online 2019-07-10]
PubMed DOI Crossref
Mitochondrial DNA analysis of a Viking age mass grave in Sweden.
Buś MM, Lembring M, Kjellström A, ..., Parson W, Allen M
Forensic Sci Int Genet 42 (-) 268-274 [2019-09-00; online 2019-06-06]
PubMed DOI Crossref
Microfluidic Immunoaffinity Basophil Activation Test for Point-of-Care Allergy Diagnosis.
Aljadi Z, Kalm F, Ramachandraiah H, ..., Lundahl J, Russom A
J Appl Lab Med 4 (2) 152-163 [2019-09-00; online 2019-05-09]
PubMed DOI Crossref
Investigation of the skin microbiome: swabs vs. biopsies.
Prast-Nielsen S, Tobin AM, Adamzik K, ..., Engstrand L, Fry L
Br. J. Dermatol. 181 (3) 572-579 [2019-09-00; online 2019-05-06]
DDLS Fellow Luisa Hugerth
PubMed DOI Crossref
Impact of demography on linked selection in two outcrossing Brassicaceae species.
Mattila TM, Laenen B, Horvath R, ..., Savolainen O, Slotte T
Ecol Evol 9 (17) 9532-9545 [2019-09-00; online 2019-08-13]
SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Genomic data provide new insights on the demographic history and the extent of recent material transfers in Norway spruce.
Chen J, Li L, Milesi P, ..., Vendramin GG, Lascoux M
Evol Appl 12 (8) 1539-1551 [2019-09-00; online 2019-04-30]
Pascal Milesi SciLifeLab Fellow
PubMed DOI Crossref
Fibroblast as a critical stromal cell type determining prognosis in prostate cancer.
Blom S, Erickson A, Östman A, ..., Kallioniemi O, Pellinen T
Prostate 79 (13) 1505-1513 [2019-09-00; online 2019-07-03]
PubMed DOI Crossref
Early life stress and voluntary alcohol consumption in relation to Maoa methylation in male rats.
Bendre M, Granholm L, Drennan R, ..., Nylander I, Comasco E
Alcohol 79 (-) 7-16 [2019-09-00; online 2018-11-08]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: descriptive characteristics of the epidemiological studies within the IMI DIRECT Consortium.
Koivula RW, Forgie IM, Kurbasic A, ..., Franks PW, IMI DIRECT Consortium
Diabetologia 62 (9) 1601-1615 [2019-09-00; online 2019-06-15]
PubMed DOI Crossref
Different epigenetic clocks reflect distinct pathophysiological features of multiple sclerosis.
Theodoropoulou E, Alfredsson L, Piehl F, Marabita F, Jagodic M
Epigenomics 11 (12) 1429-1439 [2019-09-00; online 2019-10-08]
DOI Crossref
Correlation of computed tomography with carotid plaque transcriptomes associates calcification with lesion-stabilization
Karlöf E, Seime T, Dias N, ..., Matic LP, Hedin U
Atherosclerosis 288 (-) 175-185 [2019-09-00; online 2019-09-00]
PubMed DOI Crossref
Contribution of genetics to visceral adiposity and its relation to cardiovascular and metabolic disease.
Karlsson T, Rask-Andersen M, Pan G, ..., Ek WE, Johansson Å
Nat. Med. 25 (9) 1390-1395 [2019-09-00; online 2019-09-09]
PubMed DOI Crossref
A widely used sampling device in colorectal cancer screening programmes allows for large-scale microbiome studies.
Gudra D, Shoaie S, Fridmanis D, ..., Leja M, Engstrand L
Gut 68 (9) 1723-1725 [2019-09-00; online 2018-09-21]
PubMed DOI Crossref
A genome-wide transcriptional study reveals that iron deficiency inhibits the yeast TORC1 pathway.
Romero AM, Ramos-Alonso L, Montellá-Manuel S, ..., Martínez-Pastor MT, Puig S
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1862 (9) 194414 [2019-09-00; online 2019-08-05]
DOI Crossref
633 Human skin long noncoding RNA WAKMAR1 regulates wound healing by enhancing keratinocyte migration
Li D, Kular L, Vij M, ..., Jagodic M, Xu Landén N
J. Invest. Dermatol. 139 (9) S323 [2019-09-00; online 2019-09-00]
DOI Crossref
Prototypical pacemaker neurons are immunocompetent cells
Klimovich A, Giacomello S, Björklund Å, ..., Adameyko I, Bosch TCG
- - (-) - [2019-08-30; online 2019-08-30]
DOI Crossref
Combined mRNA and protein single cell analysis in a dynamic cellular system using SPARC
Reimegård J, Danielsson M, Tarbier M, ..., Friedländer MR, Gallant CJ
- - (-) - [2019-08-28; online 2019-08-28]
PubMed DOI Crossref
Characterization of the endogenous retrovirus insertion in CYP19A1 associated with henny feathering in chicken.
Li J, Davis BW, Jern P, ..., Siegel PB, Andersson L
Mobile DNA 10 (-) 38 [2019-08-28; online 2019-08-28]
PubMed DOI Crossref
A Comparison of Functional Features in Chinese and US Mobile Apps for Diabetes Self-Management: A Systematic Search in App Stores and Content Analysis.
Wu Y, Zhou Y, Wang X, ..., Tian H, Li S
JMIR Mhealth Uhealth 7 (8) e13971 [2019-08-28; online 2019-08-28]
DOI Crossref
A Bi-LSTM Based Ensemble Algorithm for Prediction of Protein Secondary Structure
Hu H, Li Z, Elofsson A, Xie S
Applied Sciences 9 (17) 3538 [2019-08-28; online 2019-08-28]
PubMed DOI Crossref
Turning Up the Heat: Local Temperature Control During in vivo Imaging of Immune Cells.
Ahl D, Eriksson O, Sedin J, ..., Christoffersson G, Phillipson M
Front Immunol 10 (-) 2036 [2019-08-27; online 2019-08-27]
Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
Small-Molecule and CRISPR Screening Converge to Reveal Receptor Tyrosine Kinase Dependencies in Pediatric Rhabdoid Tumors.
Oberlick EM, Rees MG, Seashore-Ludlow B, ..., Schreiber SL, Roberts CWM
Cell Reports 28 (9) 2331-2344.e8 [2019-08-27; online 2019-08-29]
PubMed DOI Crossref
Prediction of Partition Coefficients of Environmental Toxins Using Computational Chemistry Methods.
van der Spoel D, Manzetti S, Zhang H, Klamt A
ACS Omega 4 (9) 13772-13781 [2019-08-27; online 2019-08-12]
DOI Crossref
A time-resolved imaging-based CRISPRi screening method
Camsund D, Lawson MJ, Larsson J, ..., Fange D, Elf J
- - (-) - [2019-08-27; online 2019-08-27]
PubMed DOI Crossref
Nanoscale dynamics of cholesterol in the cell membrane.
Pinkwart K, Schneider F, Lukoseviciute M, ..., Eggeling C, Sezgin E
J. Biol. Chem. 294 (34) 12599-12609 [2019-08-23; online 2019-07-03]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Karonudib is a promising anticancer therapy in hepatocellular carcinoma.
Hua X, Sanjiv K, Gad H, ..., Helleday T, Warpman Berglund U
Ther Adv Med Oncol 11 (-) 1758835919866960 [2019-08-23; online 2019-08-23]
PubMed DOI Crossref
Restriction of AID activity and somatic hypermutation by PARP-1.
Tepper S, Mortusewicz O, Członka E, ..., Leonhardt H, Jungnickel B
Nucleic Acids Res. 47 (14) 7418-7429 [2019-08-22; online 2019-05-28]
PubMed DOI Crossref
Human Mesenchymal glioblastomas are characterized by an increased immune cell presence compared to Proneural and Classical tumors.
Kaffes I, Szulzewsky F, Chen Z, ..., Brat DJ, Hambardzumyan D
Oncoimmunology 8 (11) e1655360 [2019-08-22; online 2019-08-22]
PubMed DOI Crossref
Editorial: Technical Advances in Cryo-Electron Microscopy.
Rivera-Calzada A, Carroni M
Front Mol Biosci 6 (-) 72 [2019-08-22; online 2019-08-22]
PubMed DOI Crossref
Clinical validation of the HPVIR high-risk HPV test on cervical samples according to the international guidelines for human papillomavirus DNA test requirements for cervical cancer screening.
Gustavsson I, Aarnio R, Myrnäs M, ..., Olovsson M, Gyllensten U
Virol. J. 16 (1) 107 [2019-08-22; online 2019-08-22]
PubMed DOI Crossref
Exhaustion of CD4+ T-cells mediated by the Kynurenine Pathway in Melanoma.
Rad Pour S, Morikawa H, Kiani NA, ..., Hansson J, Tegnér J
Sci Rep 9 (1) 12150 [2019-08-21; online 2019-08-21]
PubMed DOI Crossref
Molecular Basis and Ecological Relevance of Caulobacter Cell Filamentation in Freshwater Habitats.
Heinrich K, Leslie DJ, Morlock M, Bertilsson S, Jonas K
MBio 10 (4) - [2019-08-20; online 2019-08-20]
PubMed DOI Crossref
Progress towards the Tree of Eukaryotes.
Keeling PJ, Burki F
Curr. Biol. 29 (16) R808-R817 [2019-08-19; online 2019-08-21]
Fabien Burki SciLifeLab Fellow
DOI Crossref
Perturbation-based gene regulatory network inference to unravel oncogenic mechanisms
Morgan D, Studham M, Tjärnberg A, ..., Nordling TEM, Sonnhammer ELL
- - (-) - [2019-08-15; online 2019-08-15]
PubMed DOI Crossref
MRPS25 mutations impair mitochondrial translation and cause encephalomyopathy.
Bugiardini E, Mitchell AL, Rosa ID, ..., Pitceathly RDS, Spinazzola A
Hum. Mol. Genet. 28 (16) 2711-2719 [2019-08-15; online 2019-05-01]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer.
Cadenas C, Vosbeck S, Edlund K, ..., Marchan R, Hengstler JG
Int. J. Cancer 145 (4) 901-915 [2019-08-15; online 2019-02-07]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
IL-22 Binding Protein Promotes the Disease Process in Multiple Sclerosis.
Lindahl H, Guerreiro-Cacais AO, Bedri SK, ..., Jagodic M, Olsson T
J. Immunol. 203 (4) 888-898 [2019-08-15; online 2019-07-10]
PubMed DOI Crossref
A Discovery of a Genetic Mutation Causing Reduction of Atrogin-1 Expression in Broiler Chicken Muscle.
Li J, Hu Y, Li L, ..., Hu X, Li N
Front Genet 10 (-) 716 [2019-08-15; online 2019-08-15]
PubMed DOI Crossref
Incorporation of a Hydrophilic Spacer Reduces Hepatic Uptake of HER2-Targeting Affibody-DM1 Drug Conjugates.
Ding H, Altai M, Rinne SS, ..., Gräslund T, Orlova A
Cancers (Basel) 11 (8) - [2019-08-14; online 2019-08-14]
PubMed DOI Crossref
Vascular regression precedes motor neuron loss in the FUS (1-359) ALS mouse model.
Crivello M, Hogg MC, Jirström E, ..., Lewandowski SA, Prehn JHM
Dis Model Mech 12 (8) - [2019-08-13; online 2019-08-13]
PubMed DOI Crossref
Statistical Analysis of Community RNA Transcripts between Organic Carbon and Geogas-Fed Continental Deep Biosphere Groundwaters.
Lopez-Fernandez M, Broman E, Simone D, Bertilsson S, Dopson M
MBio 10 (4) - [2019-08-13; online 2019-08-13]
DOI Crossref
seqCAT: a Bioconductor R-package for variant analysis of high throughput sequencing data
Fasterius E, Al-Khalili Szigyarto C
F1000Res 7 (-) 1466 [2019-08-12; online 2019-08-12]
DOI Crossref
Spatial and temporal transcriptomics reveal microglia-astroglia crosstalk in the amyloid-β plaque cell niche of Alzheimer’s disease
Chen WT, Lu A, Craessaerts K, ..., Fiers M, De Strooper B
- - (-) - [2019-08-12; online 2019-08-12]
PubMed DOI Crossref
Chemoselective probe for detailed analysis of ketones and aldehydes produced by gut microbiota in human samples.
Conway LP, Garg N, Lin W, ..., Löhr JM, Globisch D
Chem. Commun. (Camb.) 55 (62) 9080-9083 [2019-08-11; online 2019-07-09]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
The Nucleolus: A Multiphase Condensate Balancing Ribosome Synthesis and Translational Capacity in Health, Aging and Ribosomopathies.
Correll CC, Bartek J, Dundr M
Cells 8 (8) - [2019-08-10; online 2019-08-10]
DOI Crossref
Progressive alignment with Cactus: a multiple-genome aligner for the thousand-genome era
Armstrong J, Hickey G, Diekhans M, ..., Zhang G, Paten B
- - (-) - [2019-08-09; online 2019-08-09]
PubMed DOI Crossref
DiscoverY: a classifier for identifying Y chromosome sequences in male assemblies.
Rangavittal S, Stopa N, Tomaszkiewicz M, ..., Makova KD, Medvedev P
BMC Genomics 20 (1) 641 [2019-08-09; online 2019-08-09]
Kristoffer Sahlin SciLifeLab Fellow
PubMed DOI Crossref
The ribosomal protein S1-dependent standby site in tisB mRNA consists of a single-stranded region and a 5' structure element.
Romilly C, Deindl S, Wagner EGH
Proc. Natl. Acad. Sci. U.S.A. 116 (32) 15901-15906 [2019-08-06; online 2019-07-18]
SciLifeLab Fellow Sebastian Deindl
PubMed DOI Crossref
Detecting and Controlling Dye Effects in Single-Virus Fusion Experiments.
Rawle RJ, Villamil Giraldo AM, Boxer SG, Kasson PM
Biophys. J. 117 (3) 445-452 [2019-08-06; online 2019-07-02]
PubMed DOI Crossref
Evaluation of Tumor-Targeting Properties of an Antagonistic Bombesin Analogue RM26 Conjugated with a Non-Residualizing Radioiodine Label Comparison with a Radiometal-Labelled Counterpart.
Oroujeni M, Abouzayed A, Lundmark F, ..., Tolmachev V, Rosenström U
Pharmaceutics 11 (8) - [2019-08-02; online 2019-08-02]
PubMed DOI Crossref
Social Parasitism in the Honeybee (Apis mellifera) Is Not Controlled by a Single SNP.
Christmas MJ, Smith NMA, Oldroyd BP, Webster MT
Mol. Biol. Evol. 36 (8) 1764-1767 [2019-08-01; online 2019-04-28]
PubMed DOI Crossref
PconsC4: fast, accurate and hassle-free contact predictions.
Michel M, Menéndez Hurtado D, Elofsson A
Bioinformatics 35 (15) 2677-2679 [2019-08-01; online 2018-12-28]
PubMed DOI Crossref
Intraspecific Diversity of Fission Yeast Mitochondrial Genomes.
Tao YT, Suo F, Tusso S, ..., Wolf JBW, Du LL
Genome Biol Evol 11 (8) 2312-2329 [2019-08-01; online 2019-08-01]
PubMed DOI Crossref
Individual Physiological Adaptations Enable Selected Bacterial Taxa To Prevail during Long-Term Incubations.
Herlemann DPR, Markert S, Meeske C, ..., Jürgens K, Schweder T
Applied and environmental microbiology 85 (15) - [2019-08-01; online 2019-07-18]
PubMed DOI Crossref
Distinct Cancer-Promoting Stromal Gene Expression Depending on Lung Function.
Sandri BJ, Masvidal L, Murie C, ..., Wendt CH, Larsson O
Am. J. Respir. Crit. Care Med. 200 (3) 348-358 [2019-08-01; online 2019-02-12]
PubMed DOI Crossref
Tools for Bioimaging Pancreatic β Cells in Diabetes.
Kang NY, Soetedjo AAP, Amirruddin NS, ..., Eriksson O, Teo AKK
Trends in molecular medicine 25 (8) 708-722 [2019-08-00; online 2019-06-06]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
The metabolites urobilin and sphingomyelin (30:1) are associated with incident heart failure in the general population.
Stenemo M, Ganna A, Salihovic S, ..., Ärnlöv J, Fall T
ESC Heart Fail 6 (4) 764-773 [2019-08-00; online 2019-05-30]
PubMed DOI Crossref
Strategies for increasing the throughput of super-resolution microscopies.
Mahecic D, Testa I, Griffié J, Manley S
Curr Opin Chem Biol 51 (-) 84-91 [2019-08-00; online 2019-06-15]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
Single-cell expression noise and gene-body methylation in Arabidopsis thaliana.
Horvath R, Laenen B, Takuno S, Slotte T
Heredity (Edinb) 123 (2) 81-91 [2019-08-00; online 2019-01-16]
SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Phosphatase inhibitor PPP1R11 modulates resistance of human T cells toward Treg-mediated suppression of cytokine expression.
Joshi RN, Fernandes SJ, Shang MM, ..., Tegnér J, Schmidt A
J Leukoc Biol 106 (2) 413-430 [2019-08-00; online 2019-03-18]
PubMed DOI Crossref
Mowat-Wilson syndrome: Generation of two human iPS cell lines (UUIGPi004A and UUIGPi005A) from siblings with a truncating ZEB2 gene variant.
Schuster J, Sobol M, Fatima A, ..., Nordgren A, Dahl N
Stem Cell Res 39 (-) 101518 [2019-08-00; online 2019-07-27]
PubMed DOI Crossref
Longitudinal analysis reveals early-pregnancy associations between perfluoroalkyl sulfonates and thyroid hormone status in a Canadian prospective birth cohort.
Reardon AJF, Khodayari Moez E, Dinu I, ..., Martin JW, APrON Study
Environ Int 129 (-) 389-399 [2019-08-00; online 2019-05-28]
PubMed DOI Crossref
Hypothalamic-pituitary-adrenal axis responsiveness, startle response, and sensorimotor gating in late pregnancy.
Breedh J, Comasco E, Hellgren C, ..., Skalkidou A, Poromaa IS
Psychoneuroendocrinology 106 (-) 1-8 [2019-08-00; online 2019-03-15]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Human prenatal exposure to polychlorinated biphenyls (PCBs) and risk behaviors in adolescence.
Dickerson AS, Ransome Y, Karlsson O
Environ Int 129 (-) 247-255 [2019-08-00; online 2019-05-27]
Oskar Karlsson SciLifeLab Fellow
PubMed DOI Crossref
Generation of three human induced pluripotent stem cell (iPSC) lines from three patients with Dravet syndrome carrying distinct SCN1A gene mutations.
Schuster J, Fatima A, Sobol M, ..., Laan L, Dahl N
Stem Cell Res 39 (-) 101523 [2019-08-00; online 2019-07-31]
PubMed DOI Crossref
Functional characterization in vitro of twelve naturally occurring variants of the human pancreatic polypeptide receptor NPY4R.
Shebanits K, Vasile S, Xu B, Gutiérrez-de-Terán H, Larhammar D
Neuropeptides 76 (-) 101933 [2019-08-00; online 2019-05-15]
PubMed DOI Crossref
Forecasting the critical role of intermittent therapies for the control of bone resorption.
Idrees M, Sohail A, Javed S
Clin Biomech (Bristol) 68 (-) 128-136 [2019-08-00; online 2019-06-07]
PubMed DOI Crossref
Engineering antigen-specific NK cell lines against the melanoma-associated antigen tyrosinase via TCR gene transfer.
Parlar A, Sayitoglu EC, Ozkazanc D, ..., Duru AD, Sutlu T
Eur. J. Immunol. 49 (8) 1278-1290 [2019-08-00; online 2019-05-17]
PubMed DOI Crossref
Cathepsin D improves the prediction of undetected diabetes in patients with myocardial infarction.
Velders MA, Calais F, Dahle N, ..., Ärnlöv J, Hedberg P
Ups. J. Med. Sci. 124 (3) 187-192 [2019-08-00; online 2019-08-20]
PubMed DOI Crossref
Breast cancer outcome prediction with tumour tissue images and machine learning.
Turkki R, Byckhov D, Lundin M, ..., Lundin J, Linder N
Breast Cancer Res. Treat. 177 (1) 41-52 [2019-08-00; online 2019-05-22]
PubMed DOI Crossref
Biodiversity loss through speciation collapse: Mechanisms, warning signals, and possible rescue.
Zhang L, Thibert-Plante X, Ripa J, Svanbäck R, Brännström Å
Evolution 73 (8) 1504-1516 [2019-08-00; online 2019-04-29]
PubMed DOI Crossref
An archaeal symbiont-host association from the deep terrestrial subsurface.
Schwank K, Bornemann TLV, Dombrowski N, ..., Banfield JF, Probst AJ
ISME J 13 (8) 2135-2139 [2019-08-00; online 2019-05-02]
PubMed DOI Crossref
Elucidating the Reprograming of Colorectal Cancer Metabolism Using Genome-Scale Metabolic Modeling.
Zhang C, Aldrees M, Arif M, ..., Mardinoglu A, Aziz MA
Front Oncol 9 (-) 681 [2019-07-30; online 2019-07-30]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
A validated single-cell-based strategy to identify diagnostic and therapeutic targets in complex diseases.
Gawel DR, Serra-Musach J, Lilja S, ..., Gustafsson M, Benson M
Genome Med 11 (1) 47 [2019-07-30; online 2019-07-30]
Antonio Lentini DDLS Fellow
DOI Crossref
Mass Spectrometry-Based Plasma Proteomics: Considerations from Sample Collection to Achieving Translational Data
Ignjatovic V, Geyer PE, Palaniappan KK, ..., Deutsch EW, Schwenk JM
- - (-) - [2019-07-26; online 2019-07-26]
PubMed DOI Crossref
Amyloid fibril polymorphism and cell-specific toxicity in vivo.
Jonson M, Nyström S, Sandberg A, ..., Thor S, Hammarström P
Amyloid 26 (sup1) 136-137 [2019-07-26; online 2019-07-26]
SciLifeLab Fellow Wojciech Michno
PubMed DOI Crossref
Spatial Chromosome Folding and Active Transcription Drive DNA Fragility and Formation of Oncogenic MLL Translocations.
Gothe HJ, Bouwman BAM, Gusmao EG, ..., Crosetto N, Roukos V
Mol. Cell 75 (2) 267-283.e12 [2019-07-25; online 2019-06-12]
DOI Crossref
Role of Host–Guest Charge Transfer in Cyclodextrin Complexation: A Computational Study
Yin C, Cui Z, Jiang Y, van der Spoel D, Zhang H
J. Phys. Chem. C 123 (29) 17745-17756 [2019-07-25; online 2019-07-01]
PubMed DOI Crossref
Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis.
Smillie CS, Biton M, Ordovas-Montanes J, ..., Xavier RJ, Regev A
Cell 178 (3) 714-730.e22 [2019-07-25; online 2019-07-28]
Sanja Vickovic SciLifeLab Fellow
DOI Crossref
Estrogen deprivation triggers an immunosuppressive phenotype in breast cancer cells
Hühn D, Martí-Rodrigo P, Mouron S, ..., Carreras-Puigvert J, Fernandez-Capetillo O
- - (-) - [2019-07-25; online 2019-07-25]
DOI Crossref
Multi-ancestry GWAS of the electrocardiographic PR interval identifies 210 loci underlying cardiac conduction
Ntalla I, Weng LC, Cartwright JH, ..., Lubitz SA, Munroe PB
- - (-) - [2019-07-24; online 2019-07-24]
PubMed DOI Crossref
α-synuclein-lipoprotein interactions and elevated ApoE level in cerebrospinal fluid from Parkinson's disease patients.
Paslawski W, Zareba-Paslawska J, Zhang X, ..., Andrén PE, Svenningsson P
Proc. Natl. Acad. Sci. U.S.A. 116 (30) 15226-15235 [2019-07-23; online 2019-07-03]
PubMed DOI Crossref
Synthesis and Preclinical Evaluation of Radio-Iodinated GRPR/PSMA Bispecific Heterodimers for the Theranostics Application in Prostate Cancer.
Abouzayed A, Yim CB, Mitran B, ..., Rosenström U, Orlova A
Pharmaceutics 11 (7) - [2019-07-23; online 2019-07-23]
PubMed DOI Crossref
A collagen-based microwell migration assay to study NK-target cell interactions.
Olofsson PE, Brandt L, Magnusson KEG, ..., Jaldén J, Önfelt B
Sci Rep 9 (1) 10672 [2019-07-23; online 2019-07-23]
PubMed DOI Crossref
An intervention targeting social, communication and daily activity skills in children and adolescents with Down syndrome and autism: a pilot study.
Wester Oxelgren U, Westerlund J, Myrelid Å, ..., Gustafsson J, Fernell E
Neuropsychiatr Dis Treat 15 (-) 2049-2056 [2019-07-18; online 2019-07-18]
PubMed DOI Crossref
Constitutive Serotonin Transporter Reduction Resembles Maternal Separation with Regard to Stress-Related Gene Expression.
Comasco E, Schijven D, de Maeyer H, ..., Sundström-Poromaa I, Olivier JDA
ACS Chem Neurosci 10 (7) 3132-3142 [2019-07-17; online 2019-01-23]
DOI Crossref
Effects of long-term warming and enhanced nitrogen and sulfur deposition on microbial communities in a boreal peatland
Martí M, Eiler A, Buck M, ..., Nilsson MB, Svensson BH
- - (-) - [2019-07-16; online 2019-07-16]
PubMed DOI Crossref
A Chemical Screen Identifies Compounds Capable of Selecting for Haploidy in Mammalian Cells.
Olbrich T, Vega-Sendino M, Murga M, ..., Ruiz S, Fernandez-Capetillo O
Cell Reports 28 (3) 597-604.e4 [2019-07-16; online 2019-07-18]
PubMed DOI Crossref
Differential Activity of ATR and WEE1 Inhibitors in a Highly Sensitive Subpopulation of DLBCL Linked to Replication Stress.
Young LA, O'Connor LO, de Renty C, ..., Lau A, O'Connor MJ
Cancer Res. 79 (14) 3762-3775 [2019-07-15; online 2019-05-23]
PubMed DOI Crossref
Assessment of weather-based influent scenarios for a WWTP: Application of a pattern recognition technique.
Borzooei S, Miranda GHB, Teegavarapu R, ..., Meucci L, Zanetti MC
J Environ Manage 242 (-) 450-456 [2019-07-15; online 2019-05-06]
Gisele Miranda SciLifeLab Fellow
PubMed DOI Crossref
The Potential Use of Metabolic Cofactors in Treatment of NAFLD.
Mardinoglu A, Ural D, Zeybel M, ..., Uhlén M, Borén J
Nutrients 11 (7) 1578 [2019-07-12; online 2019-07-12]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Sexual dimorphism in the incidence of human cancers.
Zheng D, Trynda J, Williams C, ..., McLaughlin SA, Li Z
BMC Cancer 19 (1) 684 [2019-07-12; online 2019-07-12]
PubMed DOI Crossref
Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC.
Nirwan N, Itoh Y, Singh P, ..., Amunts A, Saikrishnan K
Nat Commun 10 (1) 3058 [2019-07-11; online 2019-07-11]
Alexey Amunts SciLifeLab Fellow
DOI Crossref
Mozambican genetic variation provides new insights into the Bantu expansion
Semo A, Gayà-Vidal M, Fortes-Lima C, ..., Schlebusch C, Rocha J
- - (-) - [2019-07-10; online 2019-07-10]
DOI Crossref
Genome-wide association study provides new insights into the genetic architecture and pathogenesis of heart failure
Shah S, Henry A, Roselli C, ..., Swerdlow DI, Lumbers RT
- - (-) - [2019-07-10; online 2019-07-10]
PubMed DOI Crossref
The role of gelsolin domain 3 in familial amyloidosis (Finnish type).
Zorgati H, Larsson M, Ren W, ..., Li W, Robinson RC
Proc. Natl. Acad. Sci. U.S.A. 116 (28) 13958-13963 [2019-07-09; online 2019-06-26]
PubMed DOI Crossref
Generally applicable transcriptome-wide analysis of translation using anota2seq.
Oertlin C, Lorent J, Murie C, ..., Topisirovic I, Larsson O
Nucleic Acids Res. 47 (12) e70 [2019-07-09; online 2019-03-31]
DOI Crossref
Molecular insights from conformational ensembles via machine learning
Fleetwood O, Kasimova MA, Westerlund AM, Delemotte L
- - (-) - [2019-07-07; online 2019-07-07]
PubMed DOI Crossref
Evolution of Protein Domain Architectures.
Forslund SK, Kaduk M, Sonnhammer ELL
Methods in molecular biology (Clifton, N.J.) 1910 (-) 469-504 [2019-07-07; online 2019-07-07]
PubMed DOI Crossref
RebiQoL: A randomized trial of telemedicine patient support program for health-related quality of life and adherence in people with MS treated with Rebif.
Landtblom AM, Guala D, Martin C, ..., Jansson L, Fredrikson S
PLoS ONE 14 (7) e0218453 [2019-07-05; online 2019-07-05]
PubMed DOI Crossref
Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology.
Spracklen CN, Karaderi T, Yaghootkar H, ..., Loos RJF, Mohlke KL
Am. J. Hum. Genet. 105 (1) 15-28 [2019-07-03; online 2019-06-06]
PubMed DOI Crossref
sRNAbench and sRNAtoolbox 2019: intuitive fast small RNA profiling and differential expression.
Aparicio-Puerta E, Lebrón R, Rueda A, ..., Oliver J, Hackenberg M
Nucleic Acids Res. 47 (W1) W530-W535 [2019-07-02; online 2019-05-23]
PubMed DOI Crossref
Single-cell RNA-seq variant analysis for exploration of genetic heterogeneity in cancer.
Fasterius E, Uhlén M, Al-Khalili Szigyarto C
Sci Rep 9 (1) 9524 [2019-07-02; online 2019-07-02]
DOI Crossref
Depression, GABA and age correlate with the plasma levels of inflammatory markers
Bhandage AK, Cunningham JL, Jin Z, ..., Ekselius L, Birnir B
- - (-) - [2019-07-02; online 2019-07-02]
PubMed DOI Crossref
Reference Intervals for Fecal Calprotectin in Pregnant Women Using a Particle Enhanced Turbidimetric Assay.
Fall T, Hedman A, Pershagen G, ..., Helmersson-Karlqvist J, Larsson A
Clin. Lab. 65 (7) - [2019-07-01; online 2019-07-17]
PubMed DOI Crossref
Phosphorylation of G3BP1-S149 does not influence stress granule assembly.
Panas MD, Kedersha N, Schulte T, ..., Ivanov P, Anderson P
J. Cell Biol. 218 (7) 2425-2432 [2019-07-01; online 2019-06-06]
PubMed DOI Crossref
Coupled Enzymatic Treatment and Mass Spectrometric Analysis for Identification of Glucuronidated Metabolites in Human Samples.
Correia MSP, Rao M, Ballet C, Globisch D
Chembiochem 20 (13) 1678-1683 [2019-07-01; online 2019-05-08]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
An ErbB2/c-Src axis links bioenergetics with PRC2 translation to drive epigenetic reprogramming and mammary tumorigenesis.
Smith HW, Hirukawa A, Sanguin-Gendreau V, ..., Topisirovic I, Muller WJ
Nat Commun 10 (1) 2901 [2019-07-01; online 2019-07-01]
DOI Crossref
Abstract 3843: LSD1 modulation by allosteric ligands
Emond WB, Geitmann M, Jarvius M, ..., Segerman A, Bremberg U
Cancer Res. 79 (13_Supplement) 3843-3843 [2019-07-01; online 2019-07-01]
PubMed DOI Crossref
A Retro-biosynthesis-Based Route to Generate Pinene-Derived Polyesters.
Stamm A, Biundo A, Schmidt B, ..., Bornscheuer UT, Syrén PO
Chembiochem 20 (13) 1664-1671 [2019-07-01; online 2019-05-21]
PubMed DOI Crossref
Why do eukaryotic proteins contain more intrinsically disordered regions?
Basile W, Salvatore M, Bassot C, Elofsson A
PLoS Comput Biol 15 (7) e1007186 [2019-07-00; online 2019-07-22]
PubMed DOI Crossref
Vaginal dysbiosis and the risk of human papillomavirus and cervical cancer: systematic review and meta-analysis.
Brusselaers N, Shrestha S, van de Wijgert J, Verstraelen H
Am J Obstet Gynecol 221 (1) 9-18.e8 [2019-07-00; online 2018-12-12]
PubMed DOI Crossref
The presence and impact of reference bias on population genomic studies of prehistoric human populations.
Günther T, Nettelblad C
PLoS Genet 15 (7) e1008302 [2019-07-00; online 2019-07-26]
PubMed DOI Crossref
TANK-binding kinase 1 is a mediator of platelet-induced EMT in mammary carcinoma cells.
Zhang Y, Unnithan RVM, Hamidi A, ..., Cedervall J, Olsson AK
FASEB J. 33 (7) 7822-7832 [2019-07-00; online 2019-03-26]
PubMed DOI Crossref
Stratification of asthma phenotypes by airway proteomic signatures.
Schofield JPR, Burg D, Nicholas B, ..., Djukanović R, U-BIOPRED Study Group
J. Allergy Clin. Immunol. 144 (1) 70-82 [2019-07-00; online 2019-03-28]
PubMed DOI Crossref
Seeking the ultimate challenge.
Brodin P
Nat. Med. 25 (7) 1026 [2019-07-00; online 2019-07-05]
PubMed DOI Crossref
Regulation of the replication initiator DnaA in Caulobacter crescentus.
Felletti M, Omnus DJ, Jonas K
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1862 (7) 697-705 [2019-07-00; online 2018-01-31]
Kristina Jonas SciLifeLab Fellow
PubMed DOI Crossref
Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.
Malik R, Chauhan G, Traylor M, ..., Debette S, Dichgans M
Nat. Genet. 51 (7) 1192-1193 [2019-07-00; online 2019-06-05]
PubMed DOI Crossref
Proposal of the reverse flow model for the origin of the eukaryotic cell based on comparative analyses of Asgard archaeal metabolism.
Spang A, Stairs CW, Dombrowski N, ..., Baker BJ, Ettema TJG
Nat. Microbiol 4 (7) 1138-1148 [2019-07-00; online 2019-04-01]
PubMed DOI Crossref
Primary microcephaly, primordial dwarfism, and brachydactyly in adult cases with biallelic skipping of RTTN exon 42.
Zakaria M, Fatima A, Klar J, ..., Baig SM, Dahl N
Hum. Mutat. 40 (7) 899-903 [2019-07-00; online 2019-05-24]
PubMed DOI Crossref
Plasma Proteomics Analysis Reveals Dysregulation of Complement Proteins and Inflammation in Acquired Obesity-A Study on Rare BMI-Discordant Monozygotic Twin Pairs.
Sahebekhtiari N, Saraswat M, Joenväärä S, ..., Renkonen R, Pietiläinen KH
Proteomics Clin Appl 13 (4) e1800173 [2019-07-00; online 2019-02-05]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Outlining the proton-conduction pathway in otopetrin channels.
Delemotte L
Nat. Struct. Mol. Biol. 26 (7) 528-530 [2019-07-00; online 2019-06-27]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Methotrexate treatment in rheumatoid arthritis and elevated liver enzymes: A long-term follow-up of predictors, surveillance, and outcome in clinical practice.
Karlsson Sundbaum J, Eriksson N, Hallberg P, ..., Wadelius M, Baecklund E
Int J Rheum Dis 22 (7) 1226-1232 [2019-07-00; online 2019-04-22]
PubMed DOI Crossref
Leucocytosis is associated with retinopathy of prematurity in extremely preterm infants.
Lundgren P, Klevebro S, Brodin P, ..., Hallberg B, Hellström A
Acta Paediatr 108 (7) 1357-1358 [2019-07-00; online 2019-04-12]
PubMed DOI Crossref
Killer whale genomes reveal a complex history of recurrent admixture and vicariance.
Foote AD, Martin MD, Louis M, ..., Wolf JBW, Morin PA
Mol. Ecol. 28 (14) 3427-3444 [2019-07-00; online 2019-05-27]
PubMed DOI Crossref
Interferon-regulated suprabasin is essential for stress-induced stem-like cell conversion and therapy resistance of human malignancies.
Hubackova S, Pribyl M, Kyjacova L, ..., Bartek J, Hodny Z
Mol Oncol 13 (7) 1467-1489 [2019-07-00; online 2019-06-10]
PubMed DOI Crossref
Immune cell constitution in bone marrow microenvironment predicts outcome in adult ALL.
Hohtari H, Brück O, Blom S, ..., Porkka K, Mustjoki S
Leukemia 33 (7) 1570-1582 [2019-07-00; online 2019-01-11]
PubMed DOI Crossref
Has2 natural antisense RNA and Hmga2 promote Has2 expression during TGFβ-induced EMT in breast cancer.
Kolliopoulos C, Lin CY, Heldin CH, Moustakas A, Heldin P
Matrix Biol. 80 (-) 29-45 [2019-07-00; online 2018-09-05]
PubMed DOI Crossref
Generation of human induced pluripotent stem cell (iPSC) lines from three patients with von Hippel-Lindau syndrome carrying distinct VHL gene mutations.
Schuster J, Fatima A, Schwarz F, ..., Laan L, Dahl N
Stem Cell Res 38 (-) 101474 [2019-07-00; online 2019-05-30]
PubMed DOI Crossref
Drug-Induced Liver Injury due to Flucloxacillin: Relevance of Multiple Human Leukocyte Antigen Alleles.
Nicoletti P, Aithal GP, Chamberlain TC, ..., Daly AK, International Drug-Induced Liver Injury Consortium (iDILIC)
Clin. Pharmacol. Ther. 106 (1) 245-253 [2019-07-00; online 2019-03-19]
PubMed DOI Crossref
Dog10K: an international sequencing effort to advance studies of canine domestication, phenotypes and health.
Ostrander EA, Wang GD, Larson G, ..., Zhang YP, Dog10K Consortium
Natl Sci Rev 6 (4) 810-824 [2019-07-00; online 2019-04-10]
PubMed DOI Crossref
Different time-dependent changes of risk for evolution in chronic lymphocytic leukemia with mutated or unmutated antigen B cell receptors.
Moysiadis T, Baliakas P, Rossi D, ..., Ghia P, Stamatopoulos K
Leukemia 33 (7) 1801-1805 [2019-07-00; online 2019-01-24]
PubMed DOI Crossref
Diagnostic excision of the cervix in women over 40 years with human papilloma virus persistency and normal cytology.
Aarnio R, Wikström I, Gustavsson I, Gyllensten U, Olovsson M
Eur J Obstet Gynecol Reprod Biol X 3 (-) 100042 [2019-07-00; online 2019-05-08]
PubMed DOI Crossref
Cryo-EM structure of the activated RET signaling complex reveals the importance of its cysteine-rich domain.
Bigalke JM, Aibara S, Roth R, ..., Amunts A, Sandmark J
Sci Adv 5 (7) eaau4202 [2019-07-00; online 2019-07-31]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Consequences of a high incidence of microsatellite instability and BRAF-mutated tumors: A population-based cohort of metastatic colorectal cancer patients.
Aasebø KØ, Dragomir A, Sundström M, ..., Glimelius B, Sorbye H
Cancer Med 8 (7) 3623-3635 [2019-07-00; online 2019-05-09]
PubMed DOI Crossref
Canine transmissible venereal tumor genome reveals ancient introgression from coyotes to pre-contact dogs in North America.
Wang X, Zhou BW, Yang MA, ..., Fu Q, Zhang YP
Cell Res. 29 (7) 592-595 [2019-07-00; online 2019-06-03]
PubMed DOI Crossref
An acoustofluidic platform for non-contact trapping of cell-laden hydrogel droplets compatible with optical microscopy.
Fornell A, Johannesson C, Searle SS, ..., Nilsson J, Tenje M
Biomicrofluidics 13 (4) 044101 [2019-07-00; online 2019-07-11]
PubMed DOI Crossref
Addiction to DUSP1 protects JAK2V617F-driven polycythemia vera progenitors against inflammatory stress and DNA damage, allowing chronic proliferation.
Stetka J, Vyhlidalova P, Lanikova L, ..., Hodny Z, Divoky V
Oncogene 38 (28) 5627-5642 [2019-07-00; online 2019-04-09]
PubMed DOI Crossref
3D-Printed Whole Prostate Models with Tumor Hotspots Using Dual-Extruder Printer.
Liimatainen K, Latonen L, Kartasalo K, Ruusuvuori P
Annu Int Conf IEEE Eng Med Biol Soc 2019 (-) 2867-2871 [2019-07-00; online 2020-01-18]
DDLS Fellow Kimmo Kartasalo
PubMed DOI Crossref
The Next Generation of Pattern Recognition Receptor Agonists: Improving Response Rates in Cancer Immunotherapy.
O' Donovan DH, Mao Y, Mele DA
Current medicinal chemistry 27 (34) 5654-5674 [2019-06-30; online 2019-06-30]
SciLifeLab Fellow Yumeng Mao
PubMed DOI Crossref
Silencing of Aberrant Secretory Protein Expression by Disease-Associated Mutations.
Tikhonova EB, Karamysheva ZN, von Heijne G, Karamyshev AL
J. Mol. Biol. 431 (14) 2567-2580 [2019-06-28; online 2019-05-14]
PubMed DOI Crossref
Optimal composition and position of histidine-containing tags improves biodistribution of 99mTc-labeled DARPin G3.
Vorobyeva A, Schulga A, Konovalova E, ..., Tolmachev V, Deyev SM
Sci Rep 9 (1) 9405 [2019-06-28; online 2019-06-28]
DOI Crossref
funMotifs: Tissue-specific transcription factor motifs
Umer HM, Smolinska-Garbulowska K, Marzouka Nad, ..., Wadelius C, Komorowski J
- - (-) - [2019-06-27; online 2019-06-27]
DOI Crossref
The mitogenome of Norway spruce and a reappraisal of mitochondrial recombination in plants
Sullivan AR, Eldfjell Y, Schiffthaler B, ..., Street NR, Wang XR
- - (-) - [2019-06-27; online 2019-06-27]
PubMed DOI Crossref
Structural and mutational analysis of the ribosome-arresting human XBP1u.
Shanmuganathan V, Schiller N, Magoulopoulou A, ..., von Heijne G, Beckmann R
Elife 8 (-) - [2019-06-27; online 2019-06-27]
PubMed DOI Crossref
GPR44 as a Target for Imaging Pancreatic Beta-Cell Mass.
Eriksson O
Current diabetes reports 19 (8) 49 [2019-06-27; online 2019-06-27]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Comment on 'AIRE-deficient patients harbor unique high-affinity disease-ameliorating autoantibodies'.
Landegren N, Rosen LB, Freyhult E, ..., Anderson M, Kämpe O
Elife 8 (-) - [2019-06-27; online 2019-06-27]
PubMed DOI Crossref
A rapid smartphone-based lactate dehydrogenase test for neonatal diagnostics at the point of care.
Halvorsen CP, Olson L, Araújo AC, ..., Winbladh B, Russom A
Sci Rep 9 (1) 9301 [2019-06-26; online 2019-06-26]
PubMed DOI Crossref
A Role for the VPS Retromer in Brucella Intracellular Replication Revealed by Genomewide siRNA Screening.
Casanova A, Low SH, Québatte M, ..., Ben-Tekaya H, Dehio C
mSphere 4 (3) - [2019-06-26; online 2019-06-26]
DOI Crossref
Deriving Disease Modules from the Compressed Transcriptional Space Embedded in a Deep Auto-encoder
Dwivedi SK, Tjärnberg A, Tegnér J, Gustafsson M
- - (-) - [2019-06-24; online 2019-06-24]
PubMed DOI Crossref
Genome-Wide Analysis of Long Non-Coding RNA Profiles in Canine Oral Melanomas.
Hitte C, Le Béguec C, Cadieu E, ..., André C, Derrien T
Genes (Basel) 10 (6) - [2019-06-23; online 2019-06-23]
PubMed DOI Crossref
Serotype-specific evolutionary patterns of antimicrobial-resistant Salmonella enterica.
Liao J, Orsi RH, Carroll LM, ..., Zhang H, Wiedmann M
BMC Evol Biol BMC Evolutionary Biology 19 (1) 132 [2019-06-21; online 2019-06-21]
DDLS Fellow Laura Carroll
PubMed DOI Crossref
Indirect Radioiodination of DARPin G3 Using N-succinimidyl-Para-Iodobenzoate Improves the Contrast of HER2 Molecular Imaging.
Vorobyeva A, Schulga A, Rinne SS, ..., Deyev S, Tolmachev V
Int J Mol Sci 20 (12) - [2019-06-21; online 2019-06-21]
DOI Crossref
Shotgun Environmental DNA, Pollen, and Macrofossil Analysis of Lateglacial Lake Sediments From Southern Sweden
Parducci L, Alsos IG, Unneberg P, ..., Slotte T, Wohlfarth B
Front. Ecol. Evol. 7 (-) - [2019-06-20; online 2019-06-20]
SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Hybrid Refinement of Heterogeneous Conformational Ensembles Using Spectroscopic Data.
Hays JM, Cafiso DS, Kasson PM
J Phys Chem Lett 10 (12) 3410-3414 [2019-06-20; online 2019-06-07]
PubMed DOI Crossref
High throughput proteomics identifies a high-accuracy 11 plasma protein biomarker signature for ovarian cancer.
Enroth S, Berggrund M, Lycke M, ..., Sundfeldt K, Gyllensten U
Commun Biol 2 (-) 221 [2019-06-20; online 2019-06-20]
DOI Crossref
Author response: Structural and mutational analysis of the ribosome-arresting human XBP1u
Shanmuganathan V, Schiller N, Magoulopoulou A, ..., von Heijne G, Beckmann R
- - (-) - [2019-06-19; online 2019-06-19]
PubMed DOI Crossref
Impact of Intracellular Concentrations on Metabolic Drug-Drug Interaction Studies.
Treyer A, Ullah M, Parrott N, ..., Fowler S, Artursson P
AAPS J 21 (5) 77 [2019-06-18; online 2019-06-18]
DOI Crossref
Immune cells lacking Y chromosome have widespread dysregulation of autosomal genes
Dumanski JP, Halvardson J, Davies H, ..., Ryś J, Forsberg LA
- - (-) - [2019-06-18; online 2019-06-18]
PubMed DOI Crossref
Mitotically heritable effects of BMAA on striatal neural stem cell proliferation and differentiation.
Pierozan P, Karlsson O
Cell Death Dis 10 (7) 478 [2019-06-17; online 2019-06-17]
Oskar Karlsson SciLifeLab Fellow
PubMed DOI Crossref
Conformational switches control early maturation of the eukaryotic small ribosomal subunit.
Hunziker M, Barandun J, Buzovetsky O, ..., Molina H, Klinge S
Elife 8 (-) - [2019-06-17; online 2019-06-17]
Jonas Barandun SciLifeLab Fellow
PubMed DOI Crossref
Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen.
Menden MP, Wang D, Mason MJ, ..., Dry JR, Saez-Rodriguez J
Nat Commun 10 (1) 2674 [2019-06-17; online 2019-06-17]
PubMed DOI Crossref
Terrestrial diet influences mercury bioaccumulation in zooplankton and macroinvertebrates in lakes with differing dissolved organic carbon concentrations.
Wu P, Kainz M, Åkerblom S, ..., Bergström AK, Bishop K
Sci. Total Environ. 669 (-) 821-832 [2019-06-15; online 2019-03-13]
PubMed DOI Crossref
Dietary Fiber in Bilberry Ameliorates Pre-Obesity Events in Rats by Regulating Lipid Depot, Cecal Short-Chain Fatty Acid Formation and Microbiota Composition.
Liu HY, Walden TB, Cai D, ..., Nyman M, Holm L
Nutrients 11 (6) - [2019-06-15; online 2019-06-15]
PubMed DOI Crossref
Colitis-induced colorectal cancer and intestinal epithelial estrogen receptor beta impact gut microbiota diversity.
Ibrahim A, Hugerth LW, Hases L, ..., Engstrand L, Williams C
Int. J. Cancer 144 (12) 3086-3098 [2019-06-15; online 2019-01-11]
DDLS Fellow Luisa Hugerth
PubMed DOI Crossref
A Novel ACKR2-Dependent Role of Fibroblast-Derived CXCL14 in Epithelial-to-Mesenchymal Transition and Metastasis of Breast Cancer.
Sjöberg E, Meyrath M, Milde L, ..., Augsten M, Östman A
Clin. Cancer Res. 25 (12) 3702-3717 [2019-06-15; online 2019-03-08]
PubMed DOI Crossref
PconsFam: An Interactive Database of Structure Predictions of Pfam Families.
Lamb J, Jarmolinska AI, Michel M, ..., Sulkowska JI, Elofsson A
J. Mol. Biol. 431 (13) 2442-2448 [2019-06-14; online 2019-02-21]
DOI Crossref
A chromosome-level assembly of the Atlantic herring – detection of a supergene and other signals of selection
Pettersson ME, Rochus CM, Han F, ..., Folkvord A, Andersson L
- - (-) - [2019-06-11; online 2019-06-11]
DOI Crossref
A simple pressure-assisted method for MicroED specimen preparation
Zhao J, Xu H, Lebrette H, ..., Högbom M, Zou X
- - (-) - [2019-06-10; online 2019-06-10]
DOI Crossref
iNetModels 2.0: an interactive visualization and database of multi-omics data
Arif M, Zhang C, Li X, ..., Uhlen M, Mardinoglu A
- - (-) - [2019-06-08; online 2019-06-08]
PubMed DOI Crossref
BarkBase: Epigenomic Annotation of Canine Genomes.
Megquier K, Genereux DP, Hekman J, ..., Hoffman A, Karlsson EK
Genes (Basel) 10 (6) - [2019-06-07; online 2019-06-07]
DOI Crossref
RMetD2: a tool for integration of relative transcriptomics data into Genome-scale metabolic models
Zhang C, Lee S, Bidkhori G, ..., Nielsen J, Mardinoglu A
- - (-) - [2019-06-06; online 2019-06-06]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
SweHLA: the high confidence HLA typing bio-resource drawn from 1 000 Swedish genomes
Nordin J, Ameur A, Lindblad-Toh K, Gyllensten U, Meadows JRS
- - (-) - [2019-06-04; online 2019-06-04]
PubMed DOI Crossref
Copy number determination of the gene for the human pancreatic polypeptide receptor NPY4R using read depth analysis and droplet digital PCR.
Shebanits K, Günther T, Johansson ACV, ..., Jakobsson M, Larhammar D
BMC Biotechnol. 19 (1) 31 [2019-06-04; online 2019-06-04]
PubMed DOI Crossref
COMBImage2: a parallel computational framework for higher-order drug combination analysis that includes automated plate design, matched filter based object counting and temporal data mining.
Chantzi E, Jarvius M, Niklasson M, Segerman A, Gustafsson MG
BMC Bioinformatics 20 (1) 304 [2019-06-04; online 2019-06-04]
PubMed DOI Crossref
Mitigating Anticipated Effects of Systematic Errors Supports Sister-Group Relationship between Xenacoelomorpha and Ambulacraria.
Philippe H, Poustka AJ, Chiodin M, ..., Martinez P, Telford MJ
Curr. Biol. 29 (11) 1818-1826.e6 [2019-06-03; online 2019-05-16]
PubMed DOI Crossref
Tumoral Pyruvate Kinase L/R as a Predictive Marker for the Treatment of Renal Cancer Patients with Sunitinib and Sorafenib.
Niinivirta M, Enblad G, Lindskog C, ..., Dragomir A, Ullenhag GJ
J. Cancer 10 (14) 3224-3231 [2019-06-02; online 2019-06-02]
PubMed DOI Crossref
Integrated analysis of competing endogenous RNA network revealing potential prognostic biomarkers of hepatocellular carcinoma.
Liao X, Wang X, Huang K, ..., Ye X, Peng T
J. Cancer 10 (14) 3267-3283 [2019-06-02; online 2019-06-02]
PubMed DOI Crossref
Low guanylyl cyclase activity in Weddell seals: implications for peripheral vasoconstriction and perfusion of the brain during diving.
Hindle AG, Allen KN, Batten AJ, ..., Zapol WM, Buys ES
Am. J. Physiol. Regul. Integr. Comp. Physiol. 316 (6) R704-R715 [2019-06-01; online 2019-03-20]
PubMed DOI Crossref
Validation of Dried Blood Spots for Maternal Biomonitoring of Nonessential Elements in an Artisanal and Small-Scale Gold Mining Area of Tanzania.
Nyanza EC, Dewey D, Bernier F, ..., Hatfield J, Martin JW
Environ Toxicol Chem 38 (6) 1285-1293 [2019-06-00; online 2019-03-23]
PubMed DOI Crossref
Using PconsC4 and PconsFold2 to Predict Protein Structure.
Bassot C, Menendez Hurtado D, Elofsson A
Curr Protoc Bioinformatics 66 (1) e75 [2019-06-00; online 2019-05-07]
DOI Crossref
Trapping of Cell-Laden Hyaluronic Acid-Acrylamide Hydrogel Droplets using Bulk Acoustic Waves
Fornell A, Johannesson C, Searle SS, ..., Nilsson J, Tenje M
- - (-) 2352-2355 [2019-06-00; online 2019-06-00]
PubMed DOI Crossref
Translating genotype data of 44,000 biobank participants into clinical pharmacogenetic recommendations: challenges and solutions.
Reisberg S, Krebs K, Lepamets M, ..., Vilo J, Milani L
Genet Med 21 (6) 1345-1354 [2019-06-00; online 2018-10-16]
DOI Crossref
The cellular proteome of pancreatic ductal adenocarcinoma
Silwal-Pandit L, Johansson H, Stålberg SM, ..., Lehtiö J, Kure E
Pancreatology 19 (-) S155 [2019-06-00; online 2019-06-00]
PubMed DOI Crossref
The Nordic Zebrafish and Husbandry Meeting 2018.
Filipek-Górniok B, Ledin J, Aleström P, Braeutigam L
Zebrafish 16 (3) 329-330 [2019-06-00; online 2019-03-05]
PubMed DOI Crossref
Targeted brain delivery of methotrexate by glutathione PEGylated liposomes: How can the formulation make a difference?
Hu Y, Gaillard PJ, de Lange ECM, Hammarlund-Udenaes M
Eur J Pharm Biopharm 139 (-) 197-204 [2019-06-00; online 2019-04-02]
PubMed DOI Crossref
Separate domains of G3BP promote efficient clustering of alphavirus replication complexes and recruitment of the translation initiation machinery.
Götte B, Panas MD, Hellström K, ..., Ahola T, McInerney GM
PLoS Pathog 15 (6) e1007842 [2019-06-00; online 2019-06-14]
DOI Crossref
S843 THE PROLIFERATIVE HISTORY SHAPES THE DNA METHYLOME OF B‐CELL TUMORS AND PREDICTS CLINICAL OUTCOME
Duran‐Ferrer M, Clot G, Nadeu F, ..., Campo E, Martín‐Subero JI
Hemasphere 3 (S1) 376 [2019-06-00; online 2019-06-30]
PubMed DOI Crossref
Release of paused RNA polymerase II at specific loci favors DNA double-strand-break formation and promotes cancer translocations.
Dellino GI, Palluzzi F, Chiariello AM, ..., Crosetto N, Pelicci PG
Nat. Genet. 51 (6) 1011-1023 [2019-06-00; online 2019-05-20]
PubMed DOI Crossref
Regulatory Immune Mechanisms beyond Regulatory T Cells.
Christoffersson G, von Herrath M
Trends Immunol. 40 (6) 482-491 [2019-06-00; online 2019-05-14]
Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
Quantification of cellular protein and redox imbalance using SILAC-iodoTMT methodology.
Vajrychova M, Salovska B, Pimkova K, ..., Bartek J, Hodny Z
Redox Biol 24 (-) 101227 [2019-06-00; online 2019-05-21]
PubMed DOI Crossref
PML nuclear bodies are recruited to persistent DNA damage lesions in an RNF168-53BP1 dependent manner and contribute to DNA repair.
Vancurova M, Hanzlikova H, Knoblochova L, ..., Hodny Z, Bartek J
DNA Repair (Amst.) 78 (-) 114-127 [2019-06-00; online 2019-04-06]
DOI Crossref
PF230 THE RNA HELICASE DDX17 PROTECTS ACUTE MYELOID LEUKEMIA CELLS AGAINST DNA DAMAGE
Jagdhane P, Garg S, Xia J, ..., Koehn M, Pabst C
Hemasphere 3 (S1) 67 [2019-06-00; online 2019-06-30]
PubMed DOI Crossref
No borders during the post-glacial assembly of European bryophytes.
Ledent A, Désamoré A, Laenen B, ..., Patiño J, Vanderpoorten A
Ecol Lett 22 (6) 973-986 [2019-06-00; online 2019-03-22]
PubMed DOI Crossref
Maternal exposure to arsenic and mercury in small-scale gold mining areas of Northern Tanzania.
Nyanza EC, Bernier FP, Manyama M, ..., Martin JW, Dewey D
Environ. Res. 173 (-) 432-442 [2019-06-00; online 2019-03-19]
PubMed DOI Crossref
Low stress resilience in late adolescence and risk of smoking, high alcohol consumption and drug use later in life.
Kennedy B, Chen R, Fang F, ..., Larsson H, Fall K
J Epidemiol Community Health 73 (6) 496-501 [2019-06-00; online 2019-02-04]
PubMed DOI Crossref
Infections increase the risk of developing Sjögren's syndrome.
Mofors J, Arkema EV, Björk A, ..., Nordmark G, Wahren-Herlenius M
J. Intern. Med. 285 (6) 670-680 [2019-06-00; online 2019-04-17]
DOI Crossref
High-Dimensional Multi-Block Analysis of Factors Associated with Thrombin Generation Potential
Lorenzo H, Misbah R, Odeber J, ..., Tregouet DA, Thiebaut R
- - (-) 453-458 [2019-06-00; online 2019-06-00]
PubMed DOI Crossref
Growth-driven displacement of protein aggregates along the cell length ensures partitioning to both daughter cells in Caulobacter crescentus.
Schramm FD, Schroeder K, Alvelid J, Testa I, Jonas K
Mol. Microbiol. 111 (6) 1430-1448 [2019-06-00; online 2019-04-03]
Ilaria Testa Kristina Jonas SciLifeLab Fellow
DOI Crossref
Genetic data and radiocarbon dating question Plovers Lake as a Middle Stone Age hominin-bearing site
Lombard M, Malmström H, Schlebusch C, ..., Zipfel B, Jakobsson M
Journal of Human Evolution 131 (-) 203-209 [2019-06-00; online 2019-06-00]
PubMed DOI Crossref
Epithelial dysregulation in obese severe asthmatics with gastro-oesophageal reflux.
Perotin JM, Schofield JPR, Wilson SJ, ..., U-BIOPRED Study Group , U-BIOPRED:
Eur. Respir. J. 53 (6) - [2019-06-00; online 2019-06-27]
DOI Crossref
Droplet Dilution Unit Operation Including Bead Washing Using Integrated Acoustophoresis
Liu Z, Fornell A, Tenje M
- - (-) 2333-2336 [2019-06-00; online 2019-06-00]
DOI Crossref
Detection methods for circulating tumor cells in the blood of patients with pancreatic cancer in a pre-operative setting
Mailian E, Kordes M, Russom A, ..., Eriksson L, Löhr JM
Pancreatology 19 (-) S117 [2019-06-00; online 2019-06-00]
PubMed DOI Crossref
Cardiometabolic Proteins Associated with Metabolic Syndrome.
Lind L, Elmståhl S, Ingelsson E
Metab Syndr Relat Disord 17 (5) 272-279 [2019-06-00; online 2019-03-18]
PubMed DOI Crossref
Biorelevant intrinsic dissolution profiling in early drug development: Fundamental, methodological, and industrial aspects.
Bergström CAS, Box K, Holm R, ..., Schäfer KJ, Teleki A
Eur J Pharm Biopharm 139 (-) 101-114 [2019-06-00; online 2019-03-09]
Alexandra Teleki SciLifeLab Fellow
PubMed DOI Crossref
Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.
Shrine N, Guyatt AL, Erzurumluoglu AM, ..., Tobin MD, Wain LV
Nat. Genet. 51 (6) 1067 [2019-06-00; online 2019-05-22]
PubMed DOI Crossref
A strategy for the identification of protein architectures directly from ion mobility mass spectrometry data reveals stabilizing subunit interactions in light harvesting complexes.
Kaldmäe M, Sahin C, Saluri M, Marklund EG, Landreh M
Protein Sci. 28 (6) 1024-1030 [2019-06-00; online 2019-04-19]
PubMed DOI Crossref
A Brief History of Protein Sorting Prediction.
Nielsen H, Tsirigos KD, Brunak S, von Heijne G
Protein J 38 (3) 200-216 [2019-06-00; online 2019-05-24]
DOI Crossref
Author response: Comment on 'AIRE-deficient patients harbor unique high-affinity disease-ameliorating autoantibodies'
Landegren N, Rosen LB, Freyhult E, ..., Anderson M, Kämpe O
- - (-) - [2019-05-31; online 2019-05-31]
PubMed DOI Crossref
Assembly and Characterization of a Pathogen Strain Collection for Produce Safety Applications: Pre-growth Conditions Have a Larger Effect on Peroxyacetic Acid Tolerance Than Strain Diversity.
Harrand AS, Kovac J, Carroll LM, ..., Kent DJ, Wiedmann M
Front Microbiol 10 (-) 1223 [2019-05-31; online 2019-05-31]
DDLS Fellow Laura Carroll
PubMed DOI Crossref
Sex differences in IL-17 contribute to chronicity in male versus female urinary tract infection.
Zychlinsky Scharff A, Rousseau M, Lacerda Mariano L, ..., Duffy D, Ingersoll MA
JCI Insight 5 (13) - [2019-05-30; online 2019-05-30]
Camila Consiglio DDLS Fellow
DOI Crossref
Membrane integration and topology of RIFIN and STEVOR proteins of the Plasmodium falciparum parasite
Andersson A, Kudva R, Magoulopoulou A, ..., Nilsson I, Tellgren-Roth Å
- - (-) - [2019-05-29; online 2019-05-29]
DOI Crossref
Cotranslational folding cooperativity of contiguous domains of α-spectrin
Kemp G, Nilsson OB, Tian P, Best RB, von Heijne G
- - (-) - [2019-05-29; online 2019-05-29]
PubMed DOI Crossref
Type I interferons in host defence and inflammatory diseases.
Crow MK, Ronnblom L
Lupus Sci Med 6 (1) e000336 [2019-05-28; online 2019-05-28]
PubMed DOI Crossref
The small GTPase Rab5c is a key regulator of trafficking of the CD93/Multimerin-2/β1 integrin complex in endothelial cell adhesion and migration.
Barbera S, Nardi F, Elia I, ..., Galvagni F, Orlandini M
Cell Commun. Signal 17 (1) 55 [2019-05-28; online 2019-05-28]
PubMed DOI Crossref
Mucus Architecture and Near-Surface Swimming Affect Distinct Salmonella Typhimurium Infection Patterns along the Murine Intestinal Tract.
Furter M, Sellin ME, Hansson GC, Hardt WD
Cell Reports 27 (9) 2665-2678.e3 [2019-05-28; online 2019-05-30]
Mikael Sellin SciLifeLab Fellow
DOI Crossref
Population history and genetic adaptation of the Fulani nomads: Inferences from genome-wide data and the lactase persistence trait
Vicente M, Priehodová E, Diallo I, ..., Černý V, Schlebusch CM
- - (-) - [2019-05-27; online 2019-05-27]
PubMed DOI Crossref
Human serum albumin-based probes for molecular targeting of macrophage scavenger receptors.
Ahmed M, Baumgartner R, Aldi S, ..., Gustafsson B, Caidahl K
Int J Nanomedicine 14 (-) 3723-3741 [2019-05-21; online 2019-05-21]
PubMed DOI Crossref
Barcoded Consortium Infections Resolve Cell Type-Dependent Salmonella enterica Serovar Typhimurium Entry Mechanisms.
Di Martino ML, Ek V, Hardt WD, Eriksson J, Sellin ME
MBio 10 (3) - [2019-05-21; online 2019-05-21]
DOI Crossref
Plasma proteomic analyses and treatment predictive biomarker candidates in melanoma patients receiving immune checkpoint blockade or targeted therapy.
Eriksson H, Babacic H, Lehtio J, Pernemalm M
J Clin Oncol 37 (15_suppl) 9574-9574 [2019-05-20; online 2019-05-20]
PubMed DOI Crossref
Ice-Age Climate Adaptations Trap the Alpine Marmot in a State of Low Genetic Diversity.
Gossmann TI, Shanmugasundram A, Börno S, ..., Timmermann B, Ralser M
Curr. Biol. 29 (10) 1712-1720.e7 [2019-05-20; online 2019-05-09]
PubMed DOI Crossref
Evidence of large genetic influences on dog ownership in the Swedish Twin Registry has implications for understanding domestication and health associations.
Fall T, Kuja-Halkola R, Dobney K, Westgarth C, Magnusson PKE
Sci Rep 9 (1) 7554 [2019-05-17; online 2019-05-17]
DOI Crossref
Detecting Novel Sequence Signals in Targeting Peptides Using Deep Learning
Almagro Armenteros JJ, Salvatore M, Emanuelsson O, ..., Elofsson A, Nielsen H
- - (-) - [2019-05-17; online 2019-05-17]
PubMed DOI Crossref
WASH phosphorylation balances endosomal versus cortical actin network integrities during epithelial morphogenesis.
Tsarouhas V, Liu D, Tsikala G, ..., Billadeau DD, Samakovlis C
Nat Commun 10 (1) 2193 [2019-05-16; online 2019-05-16]
PubMed DOI Crossref
LXRα limits TGFβ-dependent hepatocellular carcinoma associated fibroblast differentiation.
Morén A, Bellomo C, Tsubakihara Y, ..., Heldin CH, Moustakas A
Oncogenesis 8 (6) 36 [2019-05-16; online 2019-05-16]
DOI Crossref
Genetic origin and salinity history influence the reproductive success of Atlantic herring
Berg F, Slotte A, Andersson L, Folkvord A
Mar. Ecol. Prog. Ser. 617-618 (-) 81-94 [2019-05-16; online 2019-05-16]
PubMed DOI Crossref
Ultrasensitive Immunoprofiling of Plasma Extracellular Vesicles Identifies Syndecan-1 as a Potential Tool for Minimally Invasive Diagnosis of Glioma.
Indira Chandran V, Welinder C, Månsson AS, ..., Sundgren PC, Belting M
Clin. Cancer Res. 25 (10) 3115-3127 [2019-05-15; online 2019-01-24]
PubMed DOI Crossref
Lysosomotropic challenge of mast cells causes intra-granular reactive oxygen species production.
Paivandy A, Eriksson J, Melo FR, Sellin ME, Pejler G
Cell death discovery 5 (1) 95 [2019-05-15; online 2019-05-15]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
In vitro phosphodiesterase 10A (PDE10A) binding in whole hemisphere human brain using the PET radioligand [18F]MNI-659.
Svedberg MM, Varnäs K, Varrone A, ..., Halldin C, Mrzljak L
Brain Res 1711 (-) 140-145 [2019-05-15; online 2019-01-18]
PubMed DOI Crossref
Oncogenic mutations at the EGFR ectodomain structurally converge to remove a steric hindrance on a kinase-coupled cryptic epitope.
Orellana L, Thorne AH, Lema R, ..., Furnari FB, Orozco M
Proc. Natl. Acad. Sci. U.S.A. 116 (20) 10009-10018 [2019-05-14; online 2019-04-26]
PubMed DOI Crossref
Chemical Sensors Generated on Wafer-Scale Epitaxial Graphene for Application to Front-Line Drug Detection.
Karlsson M, Strandqvist C, Jussi J, ..., Fu Y, Wang Q
Sensors (Basel) 19 (10) - [2019-05-14; online 2019-05-14]
PubMed DOI Crossref
EXOSC10 is required for RPA assembly and controlled DNA end resection at DNA double-strand breaks.
Domingo-Prim J, Endara-Coll M, Bonath F, ..., Huertas P, Visa N
Nat Commun 10 (1) 2135 [2019-05-13; online 2019-05-13]
Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
Mucosal-associated invariant T cells and oral microbiome in persistent apical periodontitis.
Davanian H, Gaiser RA, Silfverberg M, ..., Engstrand L, Sällberg Chen M
Int J Oral Sci 11 (2) 16 [2019-05-09; online 2019-05-09]
DDLS Fellow Luisa Hugerth
DOI Crossref
Intra-individual changes in the frequency of mosaic loss of chromosome Y over time estimated with a new method
Danielsson M, Halvardson J, Davies H, ..., Dumanski JP, Forsberg LA
- - (-) - [2019-05-09; online 2019-05-09]
PubMed DOI Crossref
Mucispirillum schaedleri Antagonizes Salmonella Virulence to Protect Mice against Colitis.
Herp S, Brugiroux S, Garzetti D, ..., Berry D, Stecher B
Cell Host Microbe 25 (5) 681-694.e8 [2019-05-08; online 2019-04-18]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
RNAi expression tuning, microfluidic screening, and genome recombineering for improved protein production in Saccharomyces cerevisiae.
Wang G, Björk SM, Huang M, ..., Joensson HN, Petranovic D
Proc. Natl. Acad. Sci. U.S.A. 116 (19) 9324-9332 [2019-05-07; online 2019-04-18]
PubMed DOI Crossref
Multi-Omic Data Interpretation to Repurpose Subtype Specific Drug Candidates for Breast Cancer.
Turanli B, Karagoz K, Bidkhori G, ..., Mardinoglu A, Arga KY
Front Genet 10 (-) 420 [2019-05-07; online 2019-05-07]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
MAPK pathway and B cells overactivation in multiple sclerosis revealed by phosphoproteomics and genomic analysis.
Kotelnikova E, Kiani NA, Messinis D, ..., Tegner J, Villoslada P
Proc. Natl. Acad. Sci. U.S.A. 116 (19) 9671-9676 [2019-05-07; online 2019-04-19]
PubMed DOI Crossref
Image-Based Quantification of Cell Debris as a Measure of Apoptosis.
Ölander M, Handin N, Artursson P
Anal. Chem. 91 (9) 5548-5552 [2019-05-07; online 2019-04-25]
PubMed DOI Crossref
Identification of Novel Mobilized Colistin Resistance Gene mcr-9 in a Multidrug-Resistant, Colistin-Susceptible Salmonella enterica Serotype Typhimurium Isolate.
Carroll LM, Gaballa A, Guldimann C, ..., Henderson LO, Wiedmann M
MBio 10 (3) - [2019-05-07; online 2019-05-07]
DDLS Fellow Laura Carroll
PubMed DOI Crossref
Human skin long noncoding RNA WAKMAR1 regulates wound healing by enhancing keratinocyte migration.
Li D, Kular L, Vij M, ..., Jagodic M, Landén NX
Proc. Natl. Acad. Sci. U.S.A. 116 (19) 9443-9452 [2019-05-07; online 2019-04-24]
Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
Membrane Electroporation and Electropermeabilization: Mechanisms and Models.
Kotnik T, Rems L, Tarek M, Miklavčič D
Annu Rev Biophys 48 (-) 63-91 [2019-05-06; online 2019-02-20]
DOI Crossref
Energy landscapes reveal agonist control of GPCR activation via microswitches
Fleetwood O, Matricon P, Carlsson J, Delemotte L
- - (-) - [2019-05-04; online 2019-05-04]
PubMed DOI Crossref
Long Time-Scale Atomistic Simulations of the Structure and Dynamics of Transcription Factor-DNA Recognition.
Liao Q, Lüking M, Krüger DM, ..., Kasson PM, Lynn Kamerlin SC
J Phys Chem B 123 (17) 3576-3590 [2019-05-02; online 2019-04-18]
SciLifeLab Fellow Sebastian Deindl
DOI Crossref
Establishing reference samples for detection of somatic mutations and germline variants with NGS technologies
Fang LT, Zhu B, Zhao Y, ..., Wang C, Xiao W
- - (-) - [2019-05-02; online 2019-05-02]
PubMed DOI Crossref
Antibody Validation Strategy for Nuclear Receptors.
Katona B, Ibrahim A, Sundberg M, Williams C
Methods in molecular biology (Clifton, N.J.) 1966 (-) 79-99 [2019-05-02; online 2019-05-02]
PubMed DOI Crossref
Improved contrast of affibody-mediated imaging of HER3 expression in mouse xenograft model through co-injection of a trivalent affibody for in vivo blocking of hepatic uptake.
Rosestedt M, Andersson KG, Rinne SS, ..., Tolmachev V, Orlova A
Sci Rep 9 (1) 6779 [2019-05-01; online 2019-05-01]
PubMed DOI Crossref
Erratum: Experimental strategies for imaging bioparticles with femtosecond hard X-ray pulses. Corrigendum.
Daurer BJ, Okamoto K, Bielecki J, ..., Hajdu J, Larsson DSD
IUCrJ 6 (Pt 3) 500 [2019-05-01; online 2019-04-09]
PubMed DOI Crossref
A preliminary transcriptome analysis suggests a transitory effect of vitamin D on mitochondrial function in obese young Finnish subjects.
Einarsdottir E, Pekkinen M, Krjutškov K, ..., Mäkitie O, Viljakainen H
Endocr Connect 8 (5) 559-570 [2019-05-01; online 2019-04-10]
PubMed DOI Crossref
A case of systemic lupus erythematosus with C1q deficiency, increased serum interferon-α levels and high serum interferogenic activity.
Bolin K, Eloranta ML, Kozyrev SV, ..., Knight A, Rönnblom L
Rheumatology (Oxford) 58 (5) 918-919 [2019-05-01; online 2019-01-05]
PubMed DOI Crossref
Towards the new normal: Transcriptomic convergence and genomic legacy of the two subgenomes of an allopolyploid weed (Capsella bursa-pastoris).
Kryvokhyzha D, Milesi P, Duan T, ..., Glémin S, Lascoux M
PLoS Genet 15 (5) e1008131 [2019-05-00; online 2019-05-13]
Pascal Milesi SciLifeLab Fellow
PubMed DOI Crossref
Stress-related genetic polymorphisms in association with peripartum depression symptoms and stress hormones: A longitudinal population-based study.
Skalkidou A, Poromaa IS, Iliadis SI, ..., Freyhult E, Comasco E
Psychoneuroendocrinology 103 (-) 296-305 [2019-05-00; online 2019-02-07]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Single-cell analysis reveals the KIT D816V mutation in haematopoietic stem and progenitor cells in systemic mastocytosis.
Grootens J, Ungerstedt JS, Ekoff M, ..., Nilsson G, Dahlin JS
EBioMedicine 43 (-) 150-158 [2019-05-00; online 2019-04-08]
PubMed DOI Crossref
Placental inflammation, lifestyle, maternal and early child sensitisation to allergens - the assessment of lifestyle and allergic disease during infancy birth cohort.
Papadogiannakis N, Joerink M, Rindsjö E, Scheynius A, Alm J
Acta Paediatr 108 (5) 927-932 [2019-05-00; online 2018-11-19]
PubMed DOI Crossref
No evidence of a causal association of type 2 diabetes and glucose metabolism with atrial fibrillation.
Harati H, Zanetti D, Rao A, ..., Ingelsson E, Knowles JW
Diabetologia 62 (5) 800-804 [2019-05-00; online 2019-02-27]
PubMed DOI Crossref
More severe intellectual disability found in teenagers compared to younger children with Down syndrome.
Wester Oxelgren U, Myrelid Å, Annerén G, ..., Gustafsson J, Fernell E
Acta Paediatr 108 (5) 961-966 [2019-05-00; online 2018-12-25]
PubMed DOI Crossref
Impact of obesity on angiogenic and inflammatory markers in the Finnish Genetics of Pre-eclampsia Consortium (FINNPEC) cohort.
Jääskeläinen T, Heinonen S, Hämäläinen E, ..., Laivuori H, FINNPEC
Int J Obes (Lond) 43 (5) 1070-1081 [2019-05-00; online 2018-09-25]
PubMed DOI Crossref
Identification of 22 novel loci associated with urinary biomarkers of albumin, sodium, and potassium excretion.
Zanetti D, Rao A, Gustafsson S, ..., Montgomery SB, Ingelsson E
Kidney Int. 95 (5) 1197-1208 [2019-05-00; online 2019-03-12]
PubMed DOI Crossref
GM1 locates to mature amyloid structures implicating a prominent role for glycolipid-protein interactions in Alzheimer pathology.
Michno W, Wehrli PM, Zetterberg H, Blennow K, Hanrieder J
Biochim Biophys Acta Proteins Proteom 1867 (5) 458-467 [2019-05-00; online 2018-09-28]
SciLifeLab Fellow Wojciech Michno
PubMed DOI Crossref
Expression of GNAZ, encoding the Gαz protein, predicts survival in mantle cell lymphoma.
Mundt F, Merrien M, Nygren L, ..., Sander B, Wasik AM
Br. J. Haematol. 185 (4) 708-712 [2019-05-00; online 2019-02-20]
PubMed DOI Crossref
Exome sequencing in Crisponi/cold-induced sweating syndrome-like individuals reveals unpredicted alternative diagnoses.
Angius A, Uva P, Oppo M, ..., Rutsch F, Crisponi L
Clin. Genet. 95 (5) 607-614 [2019-05-00; online 2019-03-28]
PubMed DOI Crossref
Electrospray sample injection for single-particle imaging with x-ray lasers.
Bielecki J, Hantke MF, Daurer BJ, ..., Hajdu J, Maia FRNC
Sci Adv 5 (5) eaav8801 [2019-05-00; online 2019-05-03]
DOI Crossref
CoordinateCleaner: Standardized cleaning of occurrence records from biological collection databases
Zizka A, Silvestro D, Andermann T, ..., Zizka V, Antonelli A
Methods Ecol Evol 10 (5) 744-751 [2019-05-00; online 2019-02-24]
DDLS Fellow Tobias Andermann
PubMed DOI Crossref
Combining evidence from four immune cell types identifies DNA methylation patterns that implicate functionally distinct pathways during Multiple Sclerosis progression.
Ewing E, Kular L, Fernandes SJ, ..., Gomez-Cabrero D, Jagodic M
EBioMedicine 43 (-) 411-423 [2019-05-00; online 2019-04-30]
PubMed DOI Crossref
A missense mutation in TYRP1 causes the chocolate plumage color in chicken and alters melanosome structure.
Li J, Bed'hom B, Marthey S, ..., Andersson L, Tixier-Boichard M
Pigment Cell Melanoma Res 32 (3) 381-390 [2019-05-00; online 2018-12-14]
PubMed DOI Crossref
A Missense Variant in PTPN22 is a Risk Factor for Drug-induced Liver Injury.
Cirulli ET, Nicoletti P, Abramson K, ..., Drug-Induced Liver Injury Network (DILIN) investigators , International DILI consortium (iDILIC)
Gastroenterology 156 (6) 1707-1716.e2 [2019-05-00; online 2019-01-18]
PubMed DOI Crossref
Pyroglutamation of amyloid-βx-42 (Aβx-42) followed by Aβ1-40 deposition underlies plaque polymorphism in progressing Alzheimer's disease pathology.
Michno W, Nyström S, Wehrli P, ..., Zetterberg H, Hanrieder J
J Biol Chem 294 (17) 6719-6732 [2019-04-26; online 2019-02-27]
SciLifeLab Fellow Wojciech Michno
PubMed DOI Crossref
Systematic Evaluation of the Safety Threshold for Allograft Macrovesicular Steatosis in Cadaveric Liver Transplantation.
Liu Z, Jia J, Ning H, ..., Zhou L, Zheng S
Front. Physiol. 10 (-) 429 [2019-04-25; online 2019-04-25]
PubMed DOI Crossref
Integrin α10, a Novel Therapeutic Target in Glioblastoma, Regulates Cell Migration, Proliferation, and Survival.
Munksgaard Thorén M, Chmielarska Masoumi K, Krona C, ..., Holmqvist B, Lundgren-Åkerlund E
Cancers (Basel) 11 (4) - [2019-04-25; online 2019-04-25]
PubMed DOI Crossref
Atmospheric Deposition Impact on Bacterial Community Composition in the NW Mediterranean.
Marín-Beltrán I, Logue JB, Andersson AF, Peters F
Front Microbiol 10 (-) 858 [2019-04-24; online 2019-04-24]
PubMed DOI Crossref
Asgard archaea capable of anaerobic hydrocarbon cycling.
Seitz KW, Dombrowski N, Eme L, ..., Ettema TJG, Baker BJ
Nat Commun 10 (1) 1822 [2019-04-23; online 2019-04-23]
PubMed DOI Crossref
Body composition and atrial fibrillation: a Mendelian randomization study.
Tikkanen E, Gustafsson S, Knowles JW, ..., Burgess S, Ingelsson E
Eur. Heart J. 40 (16) 1277-1282 [2019-04-21; online 2019-02-06]
PubMed DOI Crossref
Non-Invasive Imaging Methodologies for Assessment of Radiation Damage to Bone Marrow and Kidneys from Peptide Receptor Radionuclide Therapy.
Ahlstedt J, Johansson E, Sydoff M, ..., Gram M, Eriksson O
Neuroendocrinology 110 (1-2) 130-138 [2019-04-19; online 2019-04-19]
Olof Eriksson SciLifeLab Fellow
DOI Crossref
Decision letter: Molecular mechanisms of human P2X3 receptor channel activation and modulation by divalent cation bound ATP
- - (-) - [2019-04-19; online 2019-04-19]
PubMed DOI Crossref
Publisher Correction: A network of chaperones prevents and detects failures in membrane protein lipid bilayer integration.
Coelho JPL, Stahl M, Bloemeke N, ..., Sieber SA, Feige MJ
Nat Commun 10 (1) 1908 [2019-04-18; online 2019-04-18]
DOI Crossref
Discovery of functional alternatively spliced PKM transcripts in human cancers
Li X, Zhang C, Kim W, ..., Uhlen M, Mardinoglu A
- - (-) - [2019-04-18; online 2019-04-18]
PubMed DOI Crossref
Attachment Patterns of Human and Avian Influenza Viruses to Trachea and Colon of 26 Bird Species - Support for the Community Concept.
Eriksson P, Lindskog C, Lorente-Leal V, ..., Jourdain E, Ellström P
Front Microbiol 10 (-) 815 [2019-04-18; online 2019-04-18]
PubMed DOI Crossref
Epigenetic Modifications in Placenta are Associated with the Child's Sensitization to Allergens.
Harb H, Alashkar Alhamwe B, Acevedo N, ..., Potaczek DP, Scheynius A
Biomed Res Int 2019 (-) 1315257 [2019-04-17; online 2019-04-17]
PubMed DOI Crossref
Hepatic posttranscriptional network comprised of CCR4-NOT deadenylase and FGF21 maintains systemic metabolic homeostasis.
Morita M, Siddiqui N, Katsumura S, ..., Yamamoto T, Sonenberg N
Proc. Natl. Acad. Sci. U.S.A. 116 (16) 7973-7981 [2019-04-16; online 2019-03-29]
PubMed DOI Crossref
The horse Y chromosome as an informative marker for tracing sire lines.
Felkel S, Vogl C, Rigler D, ..., Brem G, Wallner B
Sci Rep 9 (1) 6095 [2019-04-15; online 2019-04-15]
PubMed DOI Crossref
Direct observation of coordinated DNA movements on the nucleosome during chromatin remodelling.
Sabantsev A, Levendosky RF, Zhuang X, Bowman GD, Deindl S
Nat Commun 10 (1) 1720 [2019-04-12; online 2019-04-12]
SciLifeLab Fellow Sebastian Deindl
PubMed DOI Crossref
Receptor-Independent Transfer of Low Density Lipoprotein Cargo to Biomembranes.
Axmann M, Sezgin E, Karner A, ..., Stangl H, Plochberger B
Nano Lett. 19 (4) 2562-2567 [2019-04-10; online 2019-03-08]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
iFISH is a publically available resource enabling versatile DNA FISH to study genome architecture.
Gelali E, Girelli G, Matsumoto M, ..., Crosetto N, Bienko M
Nat Commun 10 (1) 1636 [2019-04-09; online 2019-04-09]
Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
In-depth human plasma proteome analysis captures tissue proteins and transfer of protein variants across the placenta.
Pernemalm M, Sandberg A, Zhu Y, ..., Westgren M, Lehtiö J
Elife 8 (-) - [2019-04-08; online 2019-04-08]
DOI Crossref
Multiplexed Analysis of the Secretin-like GPCR-RAMP Interactome
Lorenzen E, Dodig-Crnković T, Kotliar IB, ..., Schwenk JM, Sakmar TP
- - (-) - [2019-04-06; online 2019-04-06]
PubMed DOI Crossref
Spatiotemporal dynamics of molecular pathology in amyotrophic lateral sclerosis.
Maniatis S, Äijö T, Vickovic S, ..., Bonneau R, Phatnani H
Science (New York, N.Y.) 364 (6435) 89-93 [2019-04-05; online 2019-04-06]
Sanja Vickovic SciLifeLab Fellow
DOI Crossref
Separate domains of G3BP promote efficient clustering of alphavirus replication complexes and recruitment of the translation initiation machinery
Götte B, Panas MD, Hellström K, ..., Ahola T, McInerney GM
- - (-) - [2019-04-05; online 2019-04-05]
PubMed DOI Crossref
System-wide Profiling of RNA-Binding Proteins Uncovers Key Regulators of Virus Infection.
Garcia-Moreno M, Noerenberg M, Ni S, ..., Mohammed S, Castello A
Mol. Cell 74 (1) 196-211.e11 [2019-04-04; online 2019-02-21]
SciLifeLab Fellow Vicent Pelechano
DOI Crossref
Regulation of adenylyl cyclase 5 in striatal neurons confers the ability to detect coincident neuromodulatory signals
Bruce NJ, Narzi D, Trpevski D, ..., Carloni P, Kotaleski JH
- - (-) - [2019-04-04; online 2019-04-04]
DOI Crossref
A validated strategy to infer protein biomarkers from RNA-Seq by combining multiple mRNA splice variants and time-delay
Magnusson R, Rundquist O, Kim MJ, ..., Kim MS, Gustafsson M
- - (-) - [2019-04-04; online 2019-04-04]
PubMed DOI Crossref
QligFEP: an automated workflow for small molecule free energy calculations in Q.
Jespers W, Esguerra M, Åqvist J, Gutiérrez-de-Terán H
J Cheminform 11 (1) 26 [2019-04-02; online 2019-04-02]
PubMed DOI Crossref
Mature Human White Adipocytes Cultured under Membranes Maintain Identity, Function, and Can Transdifferentiate into Brown-like Adipocytes.
Harms MJ, Li Q, Lee S, ..., Spalding KL, Boucher J
Cell Reports 27 (1) 213-225.e5 [2019-04-02; online 2019-04-04]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Detection of bacterial pathogens and drug resistance markers using Rolling circle amplification v1
Kühnemund M, Hernandez I, Istiaq Sharif M, ..., A.M. Gijs M, Nilsson M
- - (-) - [2019-04-02; online 2019-04-02]
PubMed DOI Crossref
Case Reports of Pre-clinical Replication Studies in Metabolism and Diabetes.
von Herrath M, Pagni PP, Grove K, ..., Karlsen AE, Petersen JS
Cell Metab. 29 (4) 795-802 [2019-04-02; online 2019-03-14]
Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
New Phylogenomic Analysis of the Enigmatic Phylum Telonemia Further Resolves the Eukaryote Tree of Life.
Strassert JFH, Jamy M, Mylnikov AP, Tikhonenkov DV, Burki F
Mol. Biol. Evol. 36 (4) 757-765 [2019-04-01; online 2019-01-23]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Integrated Molecular Analysis of Undifferentiated Uterine Sarcomas Reveals Clinically Relevant Molecular Subtypes.
Binzer-Panchal A, Hardell E, Viklund B, ..., Isaksson A, Carlson JW
Clin. Cancer Res. 25 (7) 2155-2165 [2019-04-01; online 2019-01-07]
PubMed DOI Crossref
Genome Size Evolution: Small Transposons with Large Consequences.
Suh A
Curr. Biol. 29 (7) R241-R243 [2019-04-01; online 2019-04-03]
PubMed DOI Crossref
The repertoire of maternal anti-viral antibodies in human newborns.
Pou C, Nkulikiyimfura D, Henckel E, ..., Bohlin K, Brodin P
Nat. Med. 25 (4) 591-596 [2019-04-00; online 2019-03-18]
PubMed DOI Crossref
Synthesis and preclinical evaluation of the CRTH2 antagonist [11C]MK-7246 as a novel PET tracer and potential surrogate marker for pancreatic beta-cell mass.
Eriksson J, Roy T, Sawadjoon S, ..., Eriksson O, Odell LR
Nucl. Med. Biol. 71 (-) 1-10 [2019-04-00; online 2019-04-13]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
SignalP 5.0 improves signal peptide predictions using deep neural networks.
Almagro Armenteros JJ, Tsirigos KD, Sønderby CK, ..., von Heijne G, Nielsen H
Nat. Biotechnol. 37 (4) 420-423 [2019-04-00; online 2019-02-18]
PubMed DOI Crossref
Prediction of individuals at high absolute risk of esophageal squamous cell carcinoma.
Wang QL, Lagergren J, Xie SH
Gastrointest Endosc 89 (4) 726-732.e2 [2019-04-00; online 2018-10-25]
DDLS Fellow Qiaoli Wang
PubMed DOI Crossref
Measuring nanoscale diffusion dynamics in cellular membranes with super-resolution STED-FCS.
Sezgin E, Schneider F, Galiani S, ..., Lagerholm BC, Eggeling C
Nat Protoc 14 (4) 1054-1083 [2019-04-00; online 2019-03-06]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Liver macrophages regulate systemic metabolism through non-inflammatory factors.
Morgantini C, Jager J, Li X, ..., Bajgar A, Aouadi M
Nat Metab 1 (4) 445-459 [2019-04-00; online 2019-03-25]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
In vivo efficiency of antimicrobial inorganic bone grafts in osteomyelitis treatments.
Mestres G, Fernandez-Yague MA, Pastorino D, ..., Manzanares-Céspedes MC, Ginebra MP
Mater Sci Eng C Mater Biol Appl 97 (-) 84-95 [2019-04-00; online 2018-11-28]
PubMed DOI Crossref
Identification of Candidate Plasma Protein Biomarkers for Cervical Cancer Using the Multiplex Proximity Extension Assay.
Berggrund M, Enroth S, Lundberg M, ..., Olovsson M, Gyllensten U
Mol. Cell Proteomics 18 (4) 735-743 [2019-04-00; online 2019-01-28]
DOI Crossref
ITIH1 (Inter-Alpha Trypsin Inhibitor Heavy Chain 1) is a potential proteomic biomarker to predict early knee osteoarthritis. A qualification phase study using data from the osteoarthritis iniciative (OAI)
Lourido L, Ruiz-Romero C, Camacho M, ..., Nilsson P, Blanco F
Osteoarthritis and Cartilage 27 (-) S69-S70 [2019-04-00; online 2019-04-00]
PubMed DOI Crossref
Genetics of adaptation in modern chicken.
Qanbari S, Rubin CJ, Maqbool K, ..., Simianer H, Andersson L
PLoS Genet 15 (4) e1007989 [2019-04-00; online 2019-04-29]
PubMed DOI Crossref
Feedforward regulation of Myc coordinates lineage-specific with housekeeping gene expression during B cell progenitor cell differentiation.
Ferreirós-Vidal I, Carroll T, Zhang T, ..., Merkenschlager M, Gomez-Cabrero D
PLoS Biol. 17 (4) e2006506 [2019-04-00; online 2019-04-12]
PubMed DOI Crossref
Epistatic mutations under divergent selection govern phenotypic variation in the crow hybrid zone.
Knief U, Bossu CM, Saino N, ..., Weissensteiner M, Wolf JBW
Nat Ecol Evol 3 (4) 570-576 [2019-04-00; online 2019-03-25]
PubMed DOI Crossref
Dual roles of heparanase in human carotid plaque calcification.
Aldi S, Eriksson L, Kronqvist M, ..., Österholm C, Hedin U
Atherosclerosis 283 (-) 127-136 [2019-04-00; online 2019-01-05]
PubMed DOI Crossref
Discovery of therapeutic agents for prostate cancer using genome-scale metabolic modeling and drug repositioning.
Turanli B, Zhang C, Kim W, ..., Arga KY, Mardinoglu A
EBioMedicine 42 (-) 386-396 [2019-04-00; online 2019-03-21]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Deep Learning in Image Cytometry: A Review.
Gupta A, Harrison PJ, Wieslander H, ..., Sintorn I, Wählby C
Cytometry A 95 (4) 366-380 [2019-04-00; online 2018-12-19]
DDLS Fellow Kimmo Kartasalo
PubMed DOI Crossref
Comparison of tumor‑targeting properties of directly and indirectly radioiodinated designed ankyrin repeat protein (DARPin) G3 variants for molecular imaging of HER2.
Vorobyeva A, Sсhulga A, Konovalova E, ..., Deyev S, Tolmachev V
Int. J. Oncol. 54 (4) 1209-1220 [2019-04-00; online 2019-02-11]
PubMed DOI Crossref
Author Correction: Liver macrophages regulate systemic metabolism through non-inflammatory factors.
Morgantini C, Jager J, Li X, ..., Bajgar A, Aouadi M
Nat Metab 1 (4) 497 [2019-04-00; online 2019-04-01]
DOI Crossref
Attempted syntheses of N-confused hydroporphyrins through modified Lindsey routes
Xiong R, Arkhypchuk AI, Eszter Borbas K
J. Porphyrins Phthalocyanines 23 (04n05) 589-598 [2019-04-00; online 2019-05-15]
Ruisheng Xiong SciLifeLab Fellow
PubMed DOI Crossref
Absence of TXNIP in Humans Leads to Lactic Acidosis and Low Serum Methionine Linked to Deficient Respiration on Pyruvate.
Katsu-Jiménez Y, Vázquez-Calvo C, Maffezzini C, ..., Wedell A, Arnér ESJ
Diabetes 68 (4) 709-723 [2019-04-00; online 2019-02-12]
PubMed DOI Crossref
A whole-brain atlas of monosynaptic input targeting four different cell types in the medial prefrontal cortex of the mouse.
Ährlund-Richter S, Xuan Y, van Lunteren JA, ..., Meletis K, Carlén M
Nat. Neurosci. 22 (4) 657-668 [2019-04-00; online 2019-03-18]
Iskra Pollak Dorocic SciLifeLab Fellow
PubMed DOI Crossref
Heterogeneous drug tissue binding in brain regions of rats, Alzheimer's patients and controls: impact on translational drug development.
Gustafsson S, Sehlin D, Lampa E, Hammarlund-Udenaes M, Loryan I
Sci Rep 9 (1) 5308 [2019-03-29; online 2019-03-29]
DOI Crossref
Single-molecule genome assembly of the Basket Willow, Salix viminalis , reveals earliest stages of sex chromosome expansion
Almeida P, Proux-Wera E, Churcher A, ..., Berlin S, Mank JE
- - (-) - [2019-03-28; online 2019-03-28]
PubMed DOI Crossref
Myoglobinopathy is an adult-onset autosomal dominant myopathy with characteristic sarcoplasmic inclusions.
Olivé M, Engvall M, Ravenscroft G, ..., Wedell A, Laing NG
Nat Commun 10 (1) 1396 [2019-03-27; online 2019-03-27]
PubMed DOI Crossref
Mechanistic Understanding of the Interactions between Nano-Objects with Different Surface Properties and α-Synuclein.
Mohammad-Beigi H, Hosseini A, Adeli M, ..., Mahmoudi M, Hajipour MJ
ACS Nano 13 (3) 3243-3256 [2019-03-26; online 2019-02-27]
DOI Crossref
Structural and mutational analysis of the ribosome-arresting human XBP1u
Shanmuganathan V, Schiller N, Magoulopoulou A, ..., von Heijne G, Beckmann R
- - (-) - [2019-03-25; online 2019-03-25]
PubMed DOI Crossref
Changes in Cervical Human Papillomavirus (HPV) Prevalence at a Youth Clinic in Stockholm, Sweden, a Decade After the Introduction of the HPV Vaccine.
Ährlund-Richter A, Cheng L, Hu YOO, ..., Dalianis T, Du J
Front. Cell. Infect. Microbiol. 9 (-) 59 [2019-03-20; online 2019-03-20]
DOI Crossref
Faculty Opinions recommendation of Engineering Epigenetic Regulation Using Synthetic Read-Write Modules.
Elsässer S, Lafranchi L
- - (-) - [2019-03-19; online 2019-03-12]
PubMed DOI Crossref
Addendum: The FAIR Guiding Principles for scientific data management and stewardship.
Wilkinson MD, Dumontier M, Jan Aalbersberg I, ..., Zhao J, Mons B
Sci Data 6 (1) 6 [2019-03-19; online 2019-03-19]
PubMed DOI Crossref
Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair.
Ma J, Benitez JA, Li J, ..., Chen CC, Furnari FB
Cancer Cell 35 (3) 504-518.e7 [2019-03-18; online 2019-02-28]
DOI Crossref
A deep learning framework for nucleus segmentation using image style transfer
Hollandi R, Szkalisity A, Toth T, ..., Smith K, Horvath P
- - (-) - [2019-03-17; online 2019-03-17]
DOI Crossref
Marine sediments illuminate Chlamydiae diversity and evolution
Dharamshi JE, Tamarit D, Eme L, ..., Spang A, Ettema TJG
- - (-) - [2019-03-16; online 2019-03-16]
PubMed DOI Crossref
Transforming growth factor β (TGFβ) induces NUAK kinase expression to fine-tune its signaling output.
Kolliopoulos C, Raja E, Razmara M, ..., Moustakas A, van der Heide LP
J Biol Chem 294 (11) 4119-4136 [2019-03-15; online 2019-01-08]
PubMed DOI Crossref
ST viewer: a tool for analysis and visualization of spatial transcriptomics datasets.
Fernández Navarro J, Lundeberg J, Ståhl PL
Bioinformatics 35 (6) 1058-1060 [2019-03-15; online 2019-03-16]
DOI Crossref
Live detection of neural stem and glioblastoma cells by an oligothiophene derivative
Ilkhanizadeh S, Gracias A, Åslund AKO, ..., Hermanson O, Nilsson KPR
- - (-) - [2019-03-15; online 2019-03-15]
PubMed DOI Crossref
Graft γδ TCR Sequencing Identifies Public Clonotypes Associated with Hematopoietic Stem Cell Transplantation Efficacy in Acute Myeloid Leukemia Patients and Unravels Cytomegalovirus Impact on Repertoire Distribution.
Arruda LCM, Gaballa A, Uhlin M
J. Immunol. 202 (6) 1859-1870 [2019-03-15; online 2019-02-01]
PubMed DOI Crossref
Force-Profile Analysis of the Cotranslational Folding of HemK and Filamin Domains: Comparison of Biochemical and Biophysical Folding Assays.
Kemp G, Kudva R, de la Rosa A, von Heijne G
J. Mol. Biol. 431 (6) 1308-1314 [2019-03-15; online 2019-02-07]
PubMed DOI Crossref
Comprehensive kinetic and substrate specificity analysis of an arylsulfatase from Helix pomatia using mass spectrometry.
Correia MSP, Ballet C, Meistermann H, Conway LP, Globisch D
Bioorg. Med. Chem. 27 (6) 955-962 [2019-03-15; online 2019-01-30]
Daniel Globisch SciLifeLab Fellow
PubMed DOI Crossref
Clonal heterogeneity influences drug responsiveness in renal cancer assessed by ex vivo drug testing of multiple patient-derived cancer cells.
Saeed K, Ojamies P, Pellinen T, ..., Kallioniemi O, Östling P
Int. J. Cancer 144 (6) 1356-1366 [2019-03-15; online 2018-11-04]
DOI Crossref
Automatic rat brain segmentation from MRI using statistical shape models and random forest
Bendazzoli S, Brusini I, Damberg P, ..., Andersson L, Wang C
- - (-) 95 [2019-03-15; online 2019-03-15]
PubMed DOI Crossref
A generalized framework for controlling FDR in gene regulatory network inference.
Morgan D, Tjärnberg A, Nordling TEM, Sonnhammer ELL
Bioinformatics 35 (6) 1026-1032 [2019-03-15; online 2018-09-01]
PubMed DOI Crossref
Phylogenetic Distribution and Diversity of Bacterial Pseudo-Orthocaspases Underline Their Putative Role in Photosynthesis.
Klemenčič M, Asplund-Samuelsson J, Dolinar M, Funk C
Front Plant Sci 10 (-) 293 [2019-03-14; online 2019-03-14]
PubMed DOI Crossref
Cytogenetic complexity in chronic lymphocytic leukemia: definitions, associations, and clinical impact.
Baliakas P, Jeromin S, Iskas M, ..., Stamatopoulos K, ERIC, the European Research Initiative on CLL
Blood 133 (11) 1205-1216 [2019-03-14; online 2019-01-02]
DOI Crossref
Loss of ErbB3 redirects Integrin β1 from early endosomal recycling to secretion in extracellular vesicles
Rodrigues-Junior DM, Sáez-Ibáñez AR, Terabayashi T, ..., Moustakas A, Ferby I
- - (-) - [2019-03-13; online 2019-03-13]
DOI Crossref
Faculty Opinions recommendation of Structures of human PRC2 with its cofactors AEBP2 and JARID2.
Elsässer S
- - (-) - [2019-03-13; online 2019-03-05]
PubMed DOI Crossref
Expression of PD-L1 and PD-1 in Chemoradiotherapy-Naïve Esophageal and Gastric Adenocarcinoma: Relationship With Mismatch Repair Status and Survival.
Svensson MC, Borg D, Zhang C, ..., Leandersson K, Jirström K
Front Oncol 9 (-) 136 [2019-03-13; online 2019-03-13]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Successive crystal structure snapshots suggest the basis for MHC class I peptide loading and editing by tapasin.
Hafstrand I, Sayitoglu EC, Apavaloaei A, ..., Duru AD, Achour A
Proc. Natl. Acad. Sci. U.S.A. 116 (11) 5055-5060 [2019-03-12; online 2019-02-26]
DOI Crossref
MTH1 promotes mitotic progression to avoid oxidative DNA damage in cancer cells
Gad H, Mortusewicz O, Rudd SG, ..., Berglund UW, Helleday T
- - (-) - [2019-03-12; online 2019-03-12]
DOI Crossref
MTH1 inhibitor TH588 induces mitosis-dependent accumulation of genomic 8-oxodG and disturbs mitotic progression
Rudd SG, Gad H, Amaral N, ..., Berglund UW, Helleday T
- - (-) - [2019-03-12; online 2019-03-12]
DOI Crossref
Secondary ossification center induces and protects growth plate structure
Xie M, Gol’din P, Herdina AN, ..., Eriksson A, Chagin AS
- - (-) - [2019-03-11; online 2019-03-11]
DOI Crossref
Genomic analysis reveals shared genes and pathways in human and canine angiosarcoma
Megquier K, Turner-Maier J, Swofford R, ..., Elvers I, Lindblad-Toh K
- - (-) - [2019-03-08; online 2019-03-08]
PubMed DOI Crossref
Dog ownership and cardiovascular risk factors: a nationwide prospective register-based cohort study.
Mubanga M, Byberg L, Egenvall A, ..., Ingelsson E, Fall T
BMJ Open 9 (3) e023447 [2019-03-07; online 2019-03-07]
DOI Crossref
Quantitative multiplexed ChIP reveals global alterations that shape promoter bivalency in ground state embryonic stem cells
Kumar B, Elsässer SJ
- - (-) - [2019-03-06; online 2019-03-06]
PubMed DOI Crossref
Virus Genomes from Deep Sea Sediments Expand the Ocean Megavirome and Support Independent Origins of Viral Gigantism.
Bäckström D, Yutin N, Jørgensen SL, ..., Koonin EV, Ettema TJG
MBio 10 (2) - [2019-03-05; online 2019-03-05]
PubMed DOI Crossref
Gramicidin Increases Lipid Flip-Flop in Symmetric and Asymmetric Lipid Vesicles.
Doktorova M, Heberle FA, Marquardt D, ..., Weinstein H, Andersen OS
Biophys. J. 116 (5) 860-873 [2019-03-05; online 2019-01-25]
DDLS Fellow Milka Doktorova
PubMed DOI Crossref
A Systematic Investigation of the Malignant Functions and Diagnostic Potential of the Cancer Secretome.
Robinson JL, Feizi A, Uhlén M, Nielsen J
Cell Reports 26 (10) 2622-2635.e5 [2019-03-05; online 2019-03-07]
DOI Crossref
The sperm of Xenacoelomorpha revisited: implications for the evolution of early bilaterians
Buckland-Nicks J, Lundin K, Wallberg A
Zoomorphology 138 (1) 13-27 [2019-03-04; online 2018-11-23]
PubMed DOI Crossref
Taxonomic status of the Australian dingo: the case for Canis dingo Meyer, 1793.
Smith BP, Cairns KM, Adams JW, ..., Morrant DS, Crowther MS
Zootaxa 4564 (1) zootaxa.4564.1.6 [2019-03-04; online 2019-03-04]
PubMed DOI Crossref
Enantioselective Aminohydroxylation of Styrenyl Olefins Catalyzed by an Engineered Hemoprotein.
Cho I, Prier CK, Jia ZJ, ..., Görbe T, Arnold FH
Angew. Chem. Int. Ed. Engl. 58 (10) 3138-3142 [2019-03-04; online 2019-01-25]
PubMed DOI Crossref
A novel L1CAM isoform with angiogenic activity generated by NOVA2-mediated alternative splicing.
Angiolini F, Belloni E, Giordano M, ..., Cavallaro U, Ghigna C
Elife 8 (-) - [2019-03-04; online 2019-03-04]
PubMed DOI Crossref
Molecular Design of HER3-Targeting Affibody Molecules: Influence of Chelator and Presence of HEHEHE-Tag on Biodistribution of 68Ga-Labeled Tracers.
Dahlsson Leitao C, Rinne SS, Mitran B, ..., Löfblom J, Orlova A
Int J Mol Sci 20 (5) - [2019-03-02; online 2019-03-02]
PubMed DOI Crossref
Vertical stratification of bacteria and archaea in sediments of a small boreal humic lake.
Rissanen AJ, Peura S, Mpamah PA, ..., Mäki A, Nykänen H
FEMS Microbiol. Lett. 366 (5) - [2019-03-01; online 2019-02-27]
Sari Peura SciLifeLab Fellow
PubMed DOI Crossref
The high efficacy of muscarinic M4 receptor in D1 medium spiny neurons reverses striatal hyperdopaminergia.
Nair AG, Castro LRV, El Khoury M, ..., Hellgren-Kotaleski J, Vincent P
Neuropharmacology 146 (-) 74-83 [2019-03-01; online 2018-11-22]
PubMed DOI Crossref
Small molecule activators of the p53 response.
Ladds MJGW, Laín S
J Mol Cell Biol 11 (3) 245-254 [2019-03-01; online 2019-01-29]
PubMed DOI Crossref
Silica bead-based microfluidic device with integrated photodiodes for the rapid capture and detection of rolling circle amplification products in the femtomolar range.
Soares RRG, Neumann F, Caneira CRF, ..., Conde JP, Nilsson M
Biosens Bioelectron 128 (-) 68-75 [2019-03-01; online 2018-12-18]
PubMed DOI Crossref
Making immunotherapy 'cold' tumours 'hot' by chemotherapy-induced mutations-a misconception.
Helleday T
Ann. Oncol. 30 (3) 360-361 [2019-03-01; online 2019-01-31]
PubMed DOI Crossref
Histone Acetylation of Immune Regulatory Genes in Human Placenta in Association with Maternal Intake of Olive Oil and Fish Consumption.
Acevedo N, Frumento P, Harb H, ..., Scheynius A, Potaczek DP
Int J Mol Sci 20 (5) - [2019-03-01; online 2019-03-01]
PubMed DOI Crossref
Cytokine Profiles in Autoantibody Defined Subgroups of Systemic Lupus Erythematosus.
Torell F, Eketjäll S, Idborg H, ..., Svenungsson E, Trygg J
J. Proteome Res. 18 (3) 1208-1217 [2019-03-01; online 2019-02-18]
PubMed DOI Crossref
Container-based bioinformatics with Pachyderm.
Novella JA, Emami Khoonsari P, Herman S, ..., Kultima K, Spjuth O
Bioinformatics 35 (5) 839-846 [2019-03-01; online 2018-08-14]
PubMed DOI Crossref
The protein synthesis inhibitor brusatol normalizes high-fat diet-induced glucose intolerance in male C57BL/6 mice: role of translation factor eIF5A hypusination.
Turpaev K, Krizhanovskii C, Wang X, ..., Bergsten P, Welsh N
FASEB J. 33 (3) 3510-3522 [2019-03-00; online 2018-11-21]
DOI Crossref
The origin and diversification of the Entorrhizales: deep evolutionary roots but recent speciation with a phylogenetic and phenotypic split between associates of the Cyperaceae and Juncaceae
Riess K, Schön ME, Ziegler R, ..., Piątek M, Garnica S
Org Divers Evol 19 (1) 13-30 [2019-03-00; online 2018-12-03]
PubMed DOI Crossref
Targeting miR-34a/Pdgfra interactions partially corrects alveologenesis in experimental bronchopulmonary dysplasia.
Ruiz-Camp J, Quantius J, Lignelli E, ..., Seeger W, Morty RE
EMBO Mol Med 11 (3) - [2019-03-00; online 2019-02-17]
PubMed DOI Crossref
Targeting genotoxic and proteotoxic stress-response pathways in human prostate cancer by clinically available PARP inhibitors, vorinostat and disulfiram.
Majera D, Skrott Z, Bouchal J, ..., Mistrik M, Bartek J
Prostate 79 (4) 352-362 [2019-03-00; online 2018-11-29]
DOI Crossref
Summer comes to the Southern Ocean: how phytoplankton shape bacterioplankton communities far into the deep dark sea
Richert I, Yager PL, Dinasquet J, ..., Bertilsson S, Scofield DG
Ecosphere 10 (3) - [2019-03-00; online 2019-03-12]
PubMed DOI Crossref
Spontaneous calcium activity in metanephric mesenchymal cells regulates branching morphogenesis in the embryonic kidney.
Fontana JM, Khodus GR, Unnersjö-Jess D, ..., Aperia A, Brismar H
FASEB J. 33 (3) 4089-4096 [2019-03-00; online 2018-11-29]
PubMed DOI Crossref
Region-by-region analysis of PET, MRI, and histology in en bloc-resected oligodendrogliomas reveals intra-tumoral heterogeneity.
Roodakker KR, Alhuseinalkhudhur A, Al-Jaff M, ..., Larsson EM, Smits A
Eur. J. Nucl. Med. Mol. Imaging 46 (3) 569-579 [2019-03-00; online 2018-08-14]
PubMed DOI Crossref
Pyruvate kinase L/R is a regulator of lipid metabolism and mitochondrial function.
Liu Z, Zhang C, Lee S, ..., Boren J, Mardinoglu A
Metab. Eng. 52 (-) 263-272 [2019-03-00; online 2019-01-04]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Plant microRNAs in human sera are likely contaminants.
Fromm B, Kang W, Rovira C, ..., Friedländer MR, Tosar JP
J Nutr Biochem 65 (-) 139-140 [2019-03-00; online 2018-09-05]
Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
Pervasive population genomic consequences of genome duplication in Arabidopsis arenosa.
Monnahan P, Kolář F, Baduel P, ..., Bomblies K, Yant L
Nat Ecol Evol 3 (3) 457-468 [2019-03-00; online 2019-02-25]
SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Mucin 5B, carbonic anhydrase 9 and claudin 18 are potential theranostic markers of gallbladder carcinoma.
Espinoza JA, Riquelme I, Sagredo EA, ..., Kalergis AM, Roa JC
Histopathology 74 (4) 597-607 [2019-03-00; online 2019-01-28]
PubMed DOI Crossref
Molecular mechanisms underlying striatal synaptic plasticity: relevance to chronic alcohol consumption and seeking.
Blackwell KT, Salinas AG, Tewatia P, ..., Hellgren Kotaleski J, Lovinger DM
Eur. J. Neurosci. 49 (6) 768-783 [2019-03-00; online 2018-04-20]
PubMed DOI Crossref
Menopausal hormone therapy and biliary tract cancer: a population-based matched cohort study in Sweden.
Kilander C, Lagergren J, Konings P, Sadr-Azodi O, Brusselaers N
Acta Oncol 58 (3) 290-295 [2019-03-00; online 2019-01-18]
PubMed DOI Crossref
Loss of function, missense, and intronic variants in NOTCH1 confer different risks for left ventricular outflow tract obstructive heart defects in two European cohorts.
Helle E, Córdova-Palomera A, Ojala T, ..., Ashley E, Priest JR
Genet Epidemiol 43 (2) 215-226 [2019-03-00; online 2018-12-04]
PubMed DOI Crossref
Integrated Identification and Quantification Error Probabilities for Shotgun Proteomics.
The M, Käll L
Mol. Cell Proteomics 18 (3) 561-570 [2019-03-00; online 2018-11-27]
PubMed DOI Crossref
Identification of metabolic profiles associated with human exposure to perfluoroalkyl substances.
Salihovic S, Fall T, Ganna A, ..., Ingelsson E, Lind L
J Expo Sci Environ Epidemiol 29 (2) 196-205 [2019-03-00; online 2018-09-05]
PubMed DOI Crossref
High-Resolution Regulatory Maps Connect Vascular Risk Variants to Disease-Related Pathways.
Åkerborg Ö, Spalinskas R, Pradhananga S, ..., Eriksson PP, Sahlén P
Circ Genom Precis Med 12 (3) e002353 [2019-03-00; online 2019-02-21]
PubMed DOI Crossref
Genetic variation in the Estonian population: pharmacogenomics study of adverse drug effects using electronic health records.
Tasa T, Krebs K, Kals M, ..., Vilo J, Milani L
Eur. J. Hum. Genet. 27 (3) 442-454 [2019-03-00; online 2018-11-12]
PubMed DOI Crossref
Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations.
Sakornsakolpat P, Prokopenko D, Lamontagne M, ..., SpiroMeta Consortium , International COPD Genetics Consortium
Nat. Genet. 51 (3) 494-505 [2019-03-00; online 2019-02-25]
PubMed DOI Crossref
Best Practices Recommendations for Diagnostic Immunohistochemistry in Lung Cancer.
Yatabe Y, Dacic S, Borczuk AC, ..., Wistuba I, Moreira AL
J Thorac Oncol 14 (3) 377-407 [2019-03-00; online 2018-12-18]
PubMed DOI Crossref
Allergen-specific IgE over time in women before, during and after pregnancy.
Hedman AM, Lundholm C, Scheynius A, ..., Pershagen G, Almqvist C
Allergy 74 (3) 625-628 [2019-03-00; online 2018-12-09]
PubMed DOI Crossref
A synonymous germline variant in a gene encoding a cell adhesion molecule is associated with cutaneous mast cell tumour development in Labrador and Golden Retrievers.
Biasoli D, Compston-Garnett L, Ricketts SL, ..., Lindblad-Toh K, Starkey M
PLoS Genet 15 (3) e1007967 [2019-03-00; online 2019-03-22]
PubMed DOI Crossref
A simple approach for restoration of differentiation and function in cryopreserved human hepatocytes.
Ölander M, Wiśniewski JR, Flörkemeier I, ..., Urdzik J, Artursson P
Arch. Toxicol. 93 (3) 819-829 [2019-03-00; online 2018-12-17]
PubMed DOI Crossref
A comparative global proteomic analysis of the hematopoietic lineages in the crustacean Pacifastacus leniusculus.
Söderhäll I, Junkunlo K
Dev. Comp. Immunol. 92 (-) 170-178 [2019-03-00; online 2018-11-24]
DOI Crossref
A Proinflammatory Invariant Natural Killer T Cell Phenotypic State Associates with Human Graft-Versus-Host Disease Onset
Xie BJ, Erkers T, Kenyon L, ..., Maecker HT, Meyer EH
Biology of Blood and Marrow Transplantation 25 (3) S290 [2019-03-00; online 2019-03-00]
PubMed DOI Crossref
A High-throughput Bead-based Affinity Assay Enables Analysis of Genital Protein Signatures in Women At Risk of HIV Infection.
Månberg A, Bradley F, Qundos U, ..., Nilsson P, Broliden K
Mol. Cell Proteomics 18 (3) 461-476 [2019-03-00; online 2018-11-30]
PubMed DOI Crossref
The long-term prognostic and predictive capacity of cyclin D1 gene amplification in 2305 breast tumours.
Lundberg A, Lindström LS, Li J, ..., Bergh J, Tobin NP
Breast Cancer Res. 21 (1) 34 [2019-02-28; online 2019-02-28]
Arian Lundberg DDLS Fellow
DOI Crossref
High-density spatial transcriptomics arrays for in situ tissue profiling
Vickovic S, Eraslan G, Klughammer J, ..., Regev A, Ståhl PL
- - (-) - [2019-02-28; online 2019-02-28]
DOI Crossref
Ecological strategy and genetic load in the shepherd’s purse ( Capsella bursa-pastoris ) from the core and the limit of its natural range
Orsucci M, Milesi P, Hansen J, ..., Glémin S, Lascoux M
- - (-) - [2019-02-28; online 2019-02-28]
PubMed DOI Crossref
A novel mutation tolerant padlock probe design for multiplexed detection of hypervariable RNA viruses.
Ciftci S, Neumann F, Hernández-Neuta I, ..., Madaboosi N, Nilsson M
Sci Rep 9 (1) 2872 [2019-02-27; online 2019-02-27]
PubMed DOI Crossref
Sex-specific lipid molecular signatures in obesity-associated metabolic dysfunctions revealed by lipidomic characterization in ob/ob mouse.
González-Granillo M, Helguero LA, Alves E, ..., Gustafsson JÅ, Korach-André M
Biol Sex Differ 10 (1) 11 [2019-02-26; online 2019-02-26]
PubMed DOI Crossref
Long-term balancing selection drives evolution of immunity genes in Capsella.
Koenig D, Hagmann J, Li R, ..., Wright SI, Weigel D
Elife 8 (-) - [2019-02-26; online 2019-02-26]
SciLifeLab Fellow Tanja Slotte
PubMed DOI Crossref
Human Glycerol 3-Phosphate Dehydrogenase: X-ray Crystal Structures That Guide the Interpretation of Mutagenesis Studies.
Mydy LS, Cristobal JR, Katigbak RD, ..., Richard JP, Gulick AM
Biochemistry 58 (8) 1061-1073 [2019-02-26; online 2019-01-31]
DOI Crossref
Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells
Samudyata , Amaral PP, Engström PG, ..., Kouzarides T, Castelo-Branco G
- - (-) - [2019-02-25; online 2019-02-25]
PubMed DOI Crossref
Biocatalysis for terpene-based polymers.
Farhat W, Stamm A, Robert-Monpate M, Biundo A, Syrén PO
Z Naturforsch C J Biosci 74 (3-4) 91-100 [2019-02-25; online 2019-02-23]
PubMed DOI Crossref
Allele specific chromatin signals, 3D interactions, and motif predictions for immune and B cell related diseases.
Cavalli M, Baltzer N, Umer HM, ..., Komorowski J, Wadelius C
Sci Rep 9 (1) 2695 [2019-02-25; online 2019-02-25]
PubMed DOI Crossref
Genetic variants and Expression of Cytochrome p450 Oxidoreductase Predict Postoperative Survival in Patients with Hepatitis B Virus-Related Hepatocellular Carcinoma.
Huang K, Liao X, Han C, ..., Ye X, Peng T
J. Cancer 10 (6) 1453-1465 [2019-02-23; online 2019-02-23]
PubMed DOI Crossref
Evolutionary Implications of the microRNA- and piRNA Complement of Lepidodermella squamata (Gastrotricha).
Fromm B, Tosar JP, Aguilera F, ..., Bachmann L, Hejnol A
Noncoding RNA 5 (1) 19 [2019-02-22; online 2019-02-22]
Marc Friedländer SciLifeLab Fellow
DOI Crossref
High Spatial Resolution Profiling in Tree Species
Giacomello S, Delhomme N, Niittylä T, Tuominen H, Street NR
- - (-) 329-360 [2019-02-20; online 2019-02-20]
PubMed DOI Crossref
Two subgroups in systemic lupus erythematosus with features of antiphospholipid or Sjögren's syndrome differ in molecular signatures and treatment perspectives.
Idborg H, Zandian A, Sandberg AS, ..., Svenungsson E, Jakobsson PJ
Arthritis Res Ther 21 (1) 62 [2019-02-18; online 2019-02-18]
PubMed DOI Crossref
Quantification and discovery of sequence determinants of protein-per-mRNA amount in 29 human tissues.
Eraslan B, Wang D, Gusic M, ..., Kuster B, Gagneur J
Mol Syst Biol 15 (2) e8513 [2019-02-18; online 2019-02-18]
PubMed DOI Crossref
First-in-class positron emission tomography tracer for the glucagon receptor.
Velikyan I, Haack T, Bossart M, ..., Wagner M, Eriksson O
EJNMMI Res 9 (1) 17 [2019-02-15; online 2019-02-15]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Exploration of extracellular vesicles from Ascaris suum provides evidence of parasite-host cross talk.
Hansen EP, Fromm B, Andersen SD, ..., Thamsborg SM, Nejsum P
J Extracell Vesicles 8 (1) 1578116 [2019-02-14; online 2019-02-14]
PubMed DOI Crossref
Heterogeneity of Metabolic Defects in Type 2 Diabetes and Its Relation to Reactive Oxygen Species and Alterations in Beta-Cell Mass.
Elksnis A, Martinell M, Eriksson O, Espes D
Front. Physiol. 10 (-) 107 [2019-02-13; online 2019-02-13]
Olof Eriksson SciLifeLab Fellow
DOI Crossref
Dynamic membrane topology in an unassembled membrane protein
Seurig M, Ek M, von Heijne G, Fluman N
- - (-) - [2019-02-13; online 2019-02-13]
DOI Crossref
Author response: In-depth human plasma proteome analysis captures tissue proteins and transfer of protein variants across the placenta
Pernemalm M, Sandberg A, Zhu Y, ..., Westgren M, Lehtiö J
- - (-) - [2019-02-13; online 2019-02-13]
PubMed DOI Crossref
Characterization of Emetic and Diarrheal Bacillus cereus Strains From a 2016 Foodborne Outbreak Using Whole-Genome Sequencing: Addressing the Microbiological, Epidemiological, and Bioinformatic Challenges.
Carroll LM, Wiedmann M, Mukherjee M, ..., Cole JA, Kovac J
Front Microbiol 10 (-) 144 [2019-02-12; online 2019-02-12]
DDLS Fellow Laura Carroll
PubMed DOI Crossref
Individualization of Hematopoietic Stem Cell Transplantation Using Alpha/Beta T-Cell Depletion.
Rådestad E, Sundin M, Törlén J, ..., Mattsson J, Uhlin M
Front Immunol 10 (-) 189 [2019-02-11; online 2019-02-11]
DOI Crossref
HybISS: Hybridization-based In Situ Sequencing v1
Gyllborg D, Nilsson M
- - (-) - [2019-02-11; online 2019-02-11]
PubMed DOI Crossref
Correction to: An Application-Directed, Versatile DNA FISH Platform for Research and Diagnostics.
Gelali E, Custodio J, Girelli G, ..., Crosetto N, Bienko M
Methods in molecular biology (Clifton, N.J.) 1766 (-) E1 [2019-02-10; online 2019-02-10]
PubMed DOI Crossref
Modeling double strand break susceptibility to interrogate structural variation in cancer.
Ballinger TJ, Bouwman BAM, Mirzazadeh R, ..., Crosetto N, Semple CA
Genome Biol. 20 (1) 28 [2019-02-08; online 2019-02-08]
DOI Crossref
Isolates from colonic spirochaetosis in humans show high genomic divergence and carry potential pathogenic features but are not detected by 16S amplicon sequencing using standard primers for the human microbiota
Thorell K, Inganäs L, Backhans A, ..., Andreasson A, Engstrand L
- - (-) - [2019-02-08; online 2019-02-08]
PubMed DOI Crossref
A network of chaperones prevents and detects failures in membrane protein lipid bilayer integration.
Coelho JPL, Stahl M, Bloemeke N, ..., Sieber SA, Feige MJ
Nat Commun 10 (1) 672 [2019-02-08; online 2019-02-08]
PubMed DOI Crossref
A conserved molecular switch in Class F receptors regulates receptor activation and pathway selection.
Wright SC, Kozielewicz P, Kowalski-Jahn M, ..., Carlsson J, Schulte G
Nat Commun 10 (1) 667 [2019-02-08; online 2019-02-08]
Jens Carlsson SciLifeLab Fellow
DOI Crossref
Spatiotemporal dissection of the cell cycle with single-cell proteogenomics
Mahdessian D, Cesnik AJ, Gnann C, ..., Sullivan D, Lundberg E
- - (-) - [2019-02-07; online 2019-02-07]
DOI Crossref
Patterns of African and Asian admixture in the Afrikaner population of South Africa
Hollfelder N, Erasmus J, Hammaren R, ..., Greeff J, Schlebusch C
- - (-) - [2019-02-07; online 2019-02-07]
PubMed DOI Crossref
Virus-Based Immunotherapy of Glioblastoma.
Martikainen M, Essand M
Cancers (Basel) 11 (2) - [2019-02-05; online 2019-02-05]
PubMed DOI Crossref
Kinetic modeling of the Calvin cycle identifies flux control and stable metabolomes in Synechocystis carbon fixation.
Janasch M, Asplund-Samuelsson J, Steuer R, Hudson EP
J. Exp. Bot. 70 (3) 973-983 [2019-02-05; online 2018-10-30]
Paul Hudson SciLifeLab Fellow
DOI Crossref
Dissection of the cellular function of the ZBED6 transcription factor in mouse myoblast cells using gene editing, RNAseq and proteomics
Younis S, Naboulsi R, Wang X, ..., Welsh N, Andersson L
- - (-) - [2019-02-05; online 2019-02-05]
DOI Crossref
A systems-based map of human brain cell-type enriched genes and malignancy-associated endothelial changes
Dusart P, Hallström BM, Renne T, ..., Uhlén M, Butler LM
- - (-) - [2019-02-05; online 2019-02-05]
PubMed DOI Crossref
A New Computational Method for Membrane Compressibility: Bilayer Mechanical Thickness Revisited.
Doktorova M, LeVine MV, Khelashvili G, Weinstein H
Biophys. J. 116 (3) 487-502 [2019-02-05; online 2019-01-03]
DDLS Fellow Milka Doktorova
PubMed DOI Crossref
Structural Patching Fosters Divergence of Mitochondrial Ribosomes.
Petrov AS, Wood EC, Bernier CR, ..., Brown A, Amunts A
Mol. Biol. Evol. 36 (2) 207-219 [2019-02-01; online 2018-12-06]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Smart scanning for low-illumination and fast RESOLFT nanoscopy in vivo.
Dreier J, Castello M, Coceano G, ..., Vicidomini G, Testa I
Nat Commun 10 (1) 556 [2019-02-01; online 2019-02-01]
Ilaria Testa SciLifeLab Fellow
PubMed DOI Crossref
DDT and its metabolites could contribute to the aetiology of chronic kidney disease of unknown aetiology (CKDu) and more studies are a priority.
Jayasinghe S, Lind L, Salihovic S, Larsson A, Lind PM
Sci. Total Environ. 649 (-) 1638-1639 [2019-02-01; online 2018-09-12]
DOI Crossref
Abstract B110: Proinflammatory allogeneic dendritic cells promote activation of bystander immune cells and indirectly license antigen-specific T-cells
Fotaki G, Jin C, Kerzeli IK, ..., Yu D, Essand M
Cancer Immunol Res 7 (2_Supplement) B110-B110 [2019-02-01; online 2019-02-01]
DOI Crossref
Abstract A128: Tumor endothelial cells say IDO to CD40-stimulating immunotherapy
Dimberg A, Karampatzakis A, Tuit S, ..., Essand M, Georganaki M
Cancer Immunol Res 7 (2_Supplement) A128-A128 [2019-02-01; online 2019-02-01]
PubMed DOI Crossref
AFISsys - An autonomous instrument for the preservation of brackish water samples for microbial metatranscriptome analysis.
Charvet S, Riemann L, Alneberg J, ..., Fischer U, Labrenz M
Water Res 149 (-) 351-361 [2019-02-01; online 2018-11-12]
PubMed DOI Crossref
miR-31 regulates energy metabolism and is suppressed in T cells from patients with Sjögren's syndrome.
Johansson A, Nyberg WA, Sjöstrand M, ..., Jagodic M, Espinosa A
Eur. J. Immunol. 49 (2) 313-322 [2019-02-00; online 2018-10-22]
PubMed DOI Crossref
Transcription-driven chromatin repression of Intragenic transcription start sites.
Nielsen M, Ard R, Leng X, ..., Pelechano V, Marquardt S
PLoS Genet 15 (2) e1007969 [2019-02-00; online 2019-02-01]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Towards a systematic understanding of differences between archaeal and bacterial diversity.
Spang A, Offre P
Environ Microbiol Rep 11 (1) 9-12 [2019-02-00; online 2018-11-05]
PubMed DOI Crossref
The genomic basis of adaptation to high-altitude habitats in the eastern honey bee (Apis cerana).
Montero-Mendieta S, Tan K, Christmas MJ, ..., Wallberg A, Webster MT
Mol. Ecol. 28 (4) 746-760 [2019-02-00; online 2019-02-04]
PubMed DOI Crossref
The contribution of lipid peroxidation to membrane permeability in electropermeabilization: A molecular dynamics study.
Rems L, Viano M, Kasimova MA, Miklavčič D, Tarek M
Bioelectrochemistry 125 (-) 46-57 [2019-02-00; online 2018-08-04]
PubMed DOI Crossref
Test-retest variability of VO2max using total-capture indirect calorimetry reveals linear relationship of VO2 and Power.
Schoffelen PFM, den Hoed M, van Breda E, Plasqui G
Scand J Med Sci Sports 29 (2) 213-222 [2019-02-00; online 2018-11-12]
PubMed DOI Crossref
Tailored approaches grounded on immunogenetic features for refined prognostication in chronic lymphocytic leukemia.
Baliakas P, Moysiadis T, Hadzidimitriou A, ..., Stamatopoulos K, European Research Initiative on CLL (ERIC)
Haematologica 104 (2) 360-369 [2019-02-00; online 2018-09-27]
PubMed DOI Crossref
T-cell inflamed tumor microenvironment predicts favorable prognosis in primary testicular lymphoma.
Leivonen SK, Pollari M, Brück O, ..., Mustjoki S, Leppä S
Haematologica 104 (2) 338-346 [2019-02-00; online 2018-09-20]
PubMed DOI Crossref
Molecular Imaging of a New Multimodal Microbubble for Adhesion Molecule Targeting.
Ahmed M, Gustafsson B, Aldi S, ..., Hedin U, Caidahl K
Cell Mol Bioeng 12 (1) 15-32 [2019-02-00; online 2018-11-28]
PubMed DOI Crossref
LGR5 promotes tumorigenicity and invasion of glioblastoma stem-like cells and is a potential therapeutic target for a subset of glioblastoma patients.
Xie Y, Sundström A, Maturi NP, ..., Jiang Y, Uhrbom L
J. Pathol. 247 (2) 228-240 [2019-02-00; online 2019-01-10]
PubMed DOI Crossref
How good are pathogenicity predictors in detecting benign variants?
Niroula A, Vihinen M
PLoS Comput Biol 15 (2) e1006481 [2019-02-00; online 2019-02-11]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
Heparan sulfate proteoglycan - A common receptor for diverse cytokines.
Xie M, Li JP
Cell. Signal. 54 (-) 115-121 [2019-02-00; online 2018-11-27]
PubMed DOI Crossref
Ex vivo culture of cells derived from circulating tumour cell xenograft to support small cell lung cancer research and experimental therapeutics.
Lallo A, Gulati S, Schenk MW, ..., Helleday T, Dive C
Br J Pharmacol 176 (3) 436-450 [2019-02-00; online 2018-12-13]
PubMed DOI Crossref
Common Genetic Variation in Relation to Brachial Vascular Dimensions and Flow-Mediated Vasodilation.
Dörr M, Hamburg NM, Müller C, ..., Benjamin EJ, Schnabel RB
Circ Genom Precis Med 12 (2) e002409 [2019-02-00; online 2019-02-20]
PubMed DOI Crossref
Characterization of heterogeneous redox responses in hepatocellular carcinoma patients using network analysis.
Benfeitas R, Bidkhori G, Mukhopadhyay B, ..., Kunos G, Mardinoglu A
EBioMedicine 40 (-) 471-487 [2019-02-00; online 2018-12-31]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Candidate biomarkers for the diagnosis and prognosis of drug-induced liver injury: An international collaborative effort.
Church RJ, Kullak-Ublick GA, Aubrecht J, ..., Poynard T, Watkins PB
Hepatology 69 (2) 760-773 [2019-02-00; online 2018-06-27]
PubMed DOI Crossref
BCG-induced cytokine release in bladder cancer cells is regulated by Ca2+ signaling.
Ibarra C, Karlsson M, Codeluppi S, ..., Miyakawa A, Uhlén P
Mol Oncol 13 (2) 202-211 [2019-02-00; online 2018-12-13]
DOI Crossref
Allosteric Modulation via Transmembrane Interfaces in a Pentameric Ligand-Gated Ion Channel
Howard RJ, Zhuang Y, Nakamura S, ..., Orellana L, Lindahl E
Biophysical Journal 116 (3) 245a-246a [2019-02-00; online 2019-02-00]
PubMed DOI Crossref
Adenosine Kinase Deficiency: Report and Review.
Alhusani A, Obaid A, Blom HJ, Wedell A, Alfadhel M
Neuropediatrics 50 (1) 46-50 [2019-02-00; online 2018-11-26]
DOI Crossref
A De Novo Mutation Associated with Epilepsy Enhances KV1.2 Voltage Dependence, Suppressing Neuronal Excitability
Pantazis A, Kaneko M, Westerlund AM, ..., Saitta S, Olcese R
Biophysical Journal 116 (3) 247a [2019-02-00; online 2019-02-00]
PubMed DOI Crossref
Evolution of vertebrate nicotinic acetylcholine receptors.
Pedersen JE, Bergqvist CA, Larhammar D
BMC Evol Biol BMC Evolutionary Biology 19 (1) 38 [2019-01-30; online 2019-01-30]
DOI Crossref
ADAMDEC1 maintains a novel growth factor signaling loop in cancer stem cells
Hale JS, Jimenez-Pascual A, Kordowski A, ..., Lathia JD, Siebzehnrubl FA
- - (-) - [2019-01-26; online 2019-01-26]
PubMed DOI Crossref
Optimization of HER3 expression imaging using affibody molecules: Influence of chelator for labeling with indium-111.
Rinne SS, Leitao CD, Mitran B, ..., Löfblom J, Orlova A
Sci Rep 9 (1) 655 [2019-01-24; online 2019-01-24]
PubMed DOI Crossref
Biochemical Differences in Cerebrospinal Fluid between Secondary Progressive and Relapsing⁻Remitting Multiple Sclerosis.
Herman S, Åkerfeldt T, Spjuth O, Burman J, Kultima K
Cells 8 (2) - [2019-01-24; online 2019-01-24]
PubMed DOI Crossref
Chromophore pre-maturation for improved speed and sensitivity of split-GFP monitoring of protein secretion.
Lundqvist M, Thalén N, Volk AL, ..., Uhlen M, Rockberg J
Sci Rep 9 (1) 310 [2019-01-22; online 2019-01-22]
PubMed DOI Crossref
Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects.
Rask-Andersen M, Karlsson T, Ek WE, Johansson Å
Nat Commun 10 (1) 339 [2019-01-21; online 2019-01-21]
PubMed DOI Crossref
A Structural Basis for 129 Xe Hyper-CEST Signal in TEM-1 β-Lactamase.
Roose BW, Zemerov SD, Wang Y, ..., Carnevale V, Dmochowski IJ
Chemphyschem 20 (2) 260-267 [2019-01-21; online 2018-09-13]
PubMed DOI Crossref
Uncertainty quantification, propagation and characterization by Bayesian analysis combined with global sensitivity analysis applied to dynamical intracellular pathway models.
Eriksson O, Jauhiainen A, Maad Sasane S, ..., Sartorius C, Hellgren Kotaleski J
Bioinformatics 35 (2) 284-292 [2019-01-15; online 2018-07-17]
PubMed DOI Crossref
TCF/LEF dependent and independent transcriptional regulation of Wnt/β-catenin target genes.
Doumpas N, Lampart F, Robinson MD, ..., Cantù C, Basler K
EMBO J. 38 (2) - [2019-01-15; online 2018-11-13]
Antonio Lentini DDLS Fellow
PubMed DOI Crossref
Discovery of KIRREL as a biomarker for prognostic stratification of patients with thin melanoma.
Lundgren S, Fagerström-Vahman H, Zhang C, ..., Nodin B, Jirström K
Biomark Res 7 (1) 1 [2019-01-14; online 2019-01-14]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Diarrheal bacterial pathogens and multi-resistant enterobacteria in the Choqueyapu River in La Paz, Bolivia.
Guzman-Otazo J, Gonzales-Siles L, Poma V, ..., Iñiguez V, Sjöling Å
PLoS ONE 14 (1) e0210735 [2019-01-14; online 2019-01-14]
DDLS Fellow Johan Bengtsson-Palme
PubMed DOI Crossref
A micro-dispenser for long-term storage and controlled release of liquids.
Kazemzadeh A, Eriksson A, Madou M, Russom A
Nat Commun 10 (1) 189 [2019-01-14; online 2019-01-14]
PubMed DOI Crossref
Transglutaminase inhibition stimulates hematopoiesis and reduces aggressive behavior of crayfish, Pacifastacus leniusculus.
Junkunlo K, Söderhäll K, Söderhäll I
J Biol Chem 294 (2) 708-715 [2019-01-11; online 2018-11-13]
PubMed DOI Crossref
Negative Association Between Allopregnanolone and Cerebral Serotonin Transporter Binding in Healthy Women of Fertile Age.
Sundström Poromaa I, Comasco E, Bäckström T, ..., Jensen P, Frokjaer VG
Front Psychol 9 (-) 2767 [2019-01-11; online 2019-01-11]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
The Circulating Transcriptome as a Source of Biomarkers for Melanoma.
Solé C, Tramonti D, Schramm M, ..., Middleton MR, Lawrie CH
Cancers (Basel) 11 (1) 70 [2019-01-10; online 2019-01-10]
Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
Decreased Snow Cover Stimulates Under-Ice Primary Producers but Impairs Methanotrophic Capacity.
Garcia SL, Szekely AJ, Bergvall C, Schattenhofer M, Peura S
mSphere 4 (1) - [2019-01-09; online 2019-01-09]
PubMed DOI Crossref
CoExpresso: assess the quantitative behavior of protein complexes in human cells.
Chalabi MH, Tsiamis V, Käll L, Vandin F, Schwämmle V
BMC Bioinformatics 20 (1) 17 [2019-01-09; online 2019-01-09]
PubMed DOI Crossref
The UNITE database for molecular identification of fungi: handling dark taxa and parallel taxonomic classifications.
Nilsson RH, Larsson KH, Taylor AFS, ..., Kõljalg U, Abarenkov K
Nucleic Acids Res. 47 (D1) D259-D264 [2019-01-08; online 2018-10-30]
DDLS Fellow Johan Bengtsson-Palme
PubMed DOI Crossref
The Pfam protein families database in 2019.
El-Gebali S, Mistry J, Bateman A, ..., Tosatto SCE, Finn RD
Nucleic Acids Res. 47 (D1) D427-D432 [2019-01-08; online 2018-10-26]
DOI Crossref
Systematic Development of Sandwich Immunoassays for the Plasma Secretome
Häussler RS, Bendes A, Iglesias M, ..., Qundos U, Schwenk JM
- - (-) - [2019-01-08; online 2019-01-08]
PubMed DOI Crossref
Improved Differential Diagnosis of Alzheimer's Disease by Integrating ELISA and Mass Spectrometry-Based Cerebrospinal Fluid Biomarkers.
Khoonsari PE, Shevchenko G, Herman S, ..., Ingelsson M, Kultima K
J. Alzheimers Dis. 67 (2) 639-651 [2019-01-08; online 2019-01-08]
DOI Crossref
Genetic predisposition to mosaic Y chromosome loss in blood is associated with genomic instability in other tissues and susceptibility to non-haematological cancers
Thompson DJ, Genovese G, Halvardson J, ..., Forsberg LA, Perry JRB
- - (-) - [2019-01-08; online 2019-01-08]
PubMed DOI Crossref
GROmaρs: A GROMACS-Based Toolset to Analyze Density Maps Derived from Molecular Dynamics Simulations.
Briones R, Blau C, Kutzner C, de Groot BL, Aponte-Santamaría C
Biophys. J. 116 (1) 4-11 [2019-01-08; online 2018-12-01]
PubMed DOI Crossref
Conventional analysis of movement on non-flat surfaces like the plasma membrane makes Brownian motion appear anomalous.
Adler J, Sintorn IM, Strand R, Parmryd I
Commun Biol 2 (-) 12 [2019-01-08; online 2019-01-08]
DOI Crossref
Causal deconvolution by algorithmic generative models
Zenil H, Kiani NA, Zea AA, Tegnér J
Nat Mach Intell 1 (1) 58-66 [2019-01-07; online 2019-01-07]
PubMed DOI Crossref
Ascetosporea.
Bass D, Ward GM, Burki F
Curr. Biol. 29 (1) R7-R8 [2019-01-07; online 2019-01-09]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Multiple-Enzyme-Digestion Strategy Improves Accuracy and Sensitivity of Label- and Standard-Free Absolute Quantification to a Level That Is Achievable by Analysis with Stable Isotope-Labeled Standard Spiking.
Wiśniewski JR, Wegler C, Artursson P
J. Proteome Res. 18 (1) 217-224 [2019-01-04; online 2018-10-30]
PubMed DOI Crossref
The BAF and PRC2 Complex Subunits Dpf2 and Eed Antagonistically Converge on Tbx3 to Control ESC Differentiation.
Zhang W, Chronis C, Chen X, ..., Sahlén P, Plath K
Cell Stem Cell 24 (1) 138-152.e8 [2019-01-03; online 2019-01-05]
PubMed DOI Crossref
The Major RNA-Binding Protein ProQ Impacts Virulence Gene Expression in Salmonella enterica Serovar Typhimurium.
Westermann AJ, Venturini E, Sellin ME, ..., Hardt WD, Vogel J
MBio 10 (1) - [2019-01-02; online 2019-01-02]
Mikael Sellin SciLifeLab Fellow
DOI Crossref
Spatial and temporal localization of immune transcripts defines hallmarks and diversity in the tuberculosis granuloma
Carow B, Hauling T, Qian X, ..., Nilsson M, Rottenberg ME
- - (-) - [2019-01-02; online 2019-01-02]
DOI Crossref
Intrinsic blinking characteristics of single colloidal CdSe-CdS/ZnS core-multishell quantum dots
Fu Y, Jussi J, Elmlund L, ..., Wang Q, Brismar H
Phys. Rev. B 99 (3) - [2019-01-02; online 2019-01-02]
PubMed DOI Crossref
A Neural Circuit Mechanism for Encoding Aversive Stimuli in the Mesolimbic Dopamine System.
de Jong JW, Afjei SA, Pollak Dorocic I, ..., Deisseroth K, Lammel S
Neuron 101 (1) 133-151.e7 [2019-01-02; online 2018-11-29]
Iskra Pollak Dorocic SciLifeLab Fellow
PubMed DOI Crossref
The importance of bioconcentration into the pelagic food web base for methylmercury biomagnification: A meta-analysis.
Wu P, Kainz MJ, Bravo AG, ..., Sonesten L, Bishop K
Sci. Total Environ. 646 (-) 357-367 [2019-01-01; online 2018-07-24]
PubMed DOI Crossref
Randomised study of HPV prevalence and detection of CIN2+ in vaginal self-sampling compared to cervical specimens collected by medical personnel.
Gustavsson I, Aarnio R, Berggrund M, ..., Olovsson M, Gyllensten U
Int. J. Cancer 144 (1) 89-97 [2019-01-01; online 2018-10-29]
PubMed DOI Crossref
Large expert-curated database for benchmarking document similarity detection in biomedical literature search.
Brown P, RELISH Consortium , Zhou Y
Database (Oxford) 2019 (-) - [2019-01-01; online 2019-01-01]
DDLS Fellow Johan Bengtsson-Palme
PubMed DOI Crossref
Genomic diversity, lifestyles and evolutionary origins of DPANN archaea.
Dombrowski N, Lee JH, Williams TA, Offre P, Spang A
FEMS Microbiol. Lett. 366 (2) - [2019-01-01; online 2019-01-11]
PubMed DOI Crossref
Allele Phasing Greatly Improves the Phylogenetic Utility of Ultraconserved Elements.
Andermann T, Fernandes AM, Olsson U, ..., Faircloth BC, Antonelli A
Syst. Biol. 68 (1) 32-46 [2019-01-01; online 2018-05-18]
DDLS Fellow Tobias Andermann
PubMed DOI Crossref
ZBED6 negatively regulates insulin production, neuronal differentiation, and cell aggregation in MIN6 cells.
Wang X, Jiang L, Wallerman O, ..., Welsh N, Andersson L
FASEB J. 33 (1) 88-100 [2019-01-00; online 2018-06-29]
PubMed DOI Crossref
The DNA Damaging Revolution: PARP Inhibitors and Beyond.
Yap TA, Plummer R, Azad NS, Helleday T
Am Soc Clin Oncol Educ Book 39 (-) 185-195 [2019-01-00; online 2019-05-17]
PubMed DOI Crossref
Ten simple rules on how to create open access and reproducible molecular simulations of biological systems.
Elofsson A, Hess B, Lindahl E, ..., van der Spoel D, Wallqvist A
PLoS Comput Biol 15 (1) e1006649 [2019-01-00; online 2019-01-17]
PubMed DOI Crossref
Temporal and long-term gut microbiota variation in allergic disease: A prospective study from infancy to school age.
Simonyté Sjödin K, Hammarström ML, Rydén P, ..., Engstrand L, West CE
Allergy 74 (1) 176-185 [2019-01-00; online 2018-10-18]
PubMed DOI Crossref
TIAR marks nuclear G2/M transition granules and restricts CDK1 activity under replication stress.
Lafarga V, Sung HM, Haneke K, ..., Fernandez-Capetillo O, Stoecklin G
EMBO Rep. 20 (1) - [2019-01-00; online 2018-12-11]
PubMed DOI Crossref
Smartphone-based clinical diagnostics: towards democratization of evidence-based health care.
Hernández-Neuta I, Neumann F, Brightmeyer J, ..., Ozcan A, Nilsson M
J. Intern. Med. 285 (1) 19-39 [2019-01-00; online 2018-09-12]
PubMed DOI Crossref
Roles for globus pallidus externa revealed in a computational model of action selection in the basal ganglia.
Suryanarayana SM, Hellgren Kotaleski J, Grillner S, Gurney KN
Neural Netw 109 (-) 113-136 [2019-01-00; online 2018-10-19]
PubMed DOI Crossref
Revisions to the Classification, Nomenclature, and Diversity of Eukaryotes.
Adl SM, Bass D, Lane CE, ..., Zlatogursky V, Zhang Q
J. Eukaryot. Microbiol. 66 (1) 4-119 [2019-01-00; online 2018-09-27]
Fabien Burki SciLifeLab Fellow
DOI Crossref
Regio- and Stereoselective Synthesis of Spirooxindoles via Mizoroki–Heck Coupling of Aryl Iodides
Larhed M, Adeyemi A, Wetzel A, Bergman J, Brånalt J
Synlett 30 (01) 82-88 [2019-01-00; online 2018-12-04]
PubMed DOI Crossref
Proteomic profiling of endothelium-dependent vasodilation.
Lind L, Sundström J, Ärnlöv J, Ingelsson E
J. Hypertens. 37 (1) 216-222 [2019-01-00; online 2018-10-20]
PubMed DOI Crossref
Pneumolysin binds to the mannose receptor C type 1 (MRC-1) leading to anti-inflammatory responses and enhanced pneumococcal survival.
Subramanian K, Neill DR, Malak HA, ..., Kadioglu A, Henriques-Normark B
Nat. Microbiol 4 (1) 62-70 [2019-01-00; online 2018-11-12]
PubMed DOI Crossref
Phylogenomics supports the monophyly of the Cercozoa.
Irwin NAT, Tikhonenkov DV, Hehenberger E, ..., Burki F, Keeling PJ
Mol. Phylogenet. Evol. 130 (-) 416-423 [2019-01-00; online 2018-10-11]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
New mitochondrial primers for metabarcoding of insects, designed and evaluated using in silico methods.
Marquina D, Andersson AF, Ronquist F
Mol Ecol Resour 19 (1) 90-104 [2019-01-00; online 2018-10-16]
PubMed DOI Crossref
NQO1*2 polymorphism predicts overall survival in MDS patients.
Moudra A, Minarik L, Vancurova M, ..., Hodny Z, Jonasova A
Br. J. Haematol. 184 (2) 305-308 [2019-01-00; online 2018-01-24]
DOI Crossref
Microzooplankton distribution in the Amundsen Sea Polynya (Antarctica) during an extensive Phaeocystis antarctica bloom
Swalethorp R, Dinasquet J, Logares R, ..., Nielsen TG, Riemann L
Progress in Oceanography 170 (-) 1-10 [2019-01-00; online 2019-01-00]
PubMed DOI Crossref
McSwan: A joint site frequency spectrum method to detect and date selective sweeps across multiple population genomes.
Tournebize R, Poncet V, Jakobsson M, Vigouroux Y, Manel S
Mol Ecol Resour 19 (1) 283-295 [2019-01-00; online 2018-11-22]
PubMed DOI Crossref
Introducing ribosomal tandem repeat barcoding for fungi.
Wurzbacher C, Larsson E, Bengtsson-Palme J, ..., Kagami M, Nilsson RH
Mol Ecol Resour 19 (1) 118-127 [2019-01-00; online 2018-10-24]
DDLS Fellow Johan Bengtsson-Palme
PubMed DOI Crossref
Host-derived population genomics data provides insights into bacterial and diatom composition of the killer whale skin.
Hooper R, Brealey JC, van der Valk T, ..., Foote AD, Guschanski K
Mol. Ecol. 28 (2) 484-502 [2019-01-00; online 2018-10-24]
DOI Crossref
Flood pulse regulation of bacterioplankton community composition in an Amazonian floodplain lake
de Melo ML, Bertilsson S, Amaral JHF, ..., Forsberg BR, Sarmento H
Freshw Biol 64 (1) 108-120 [2019-01-00; online 2018-11-05]
DOI Crossref
Extraction and quantification of phycobiliproteins from the red alga Furcellaria lumbricalis
Saluri M, Kaldmäe M, Tuvikene R
Algal Research 37 (-) 115-123 [2019-01-00; online 2019-01-00]
PubMed DOI Crossref
Error-prone bypass of DNA lesions during lagging-strand replication is a common source of germline and cancer mutations.
Seplyarskiy VB, Akkuratov EE, Akkuratova N, ..., Adameyko I, Sunyaev SR
Nat. Genet. 51 (1) 36-41 [2019-01-00; online 2018-12-03]
PubMed DOI Crossref
Combined epithelial marker analysis of tumour budding in stage II colorectal cancer.
Slik K, Blom S, Turkki R, ..., Sundström J, Pellinen T
J Pathol Clin Res 5 (1) 63-78 [2019-01-00; online 2018-11-29]
PubMed DOI Crossref
Chimeric padlock and iLock probes for increased efficiency of targeted RNA detection.
Krzywkowski T, Kühnemund M, Nilsson M
RNA 25 (1) 82-89 [2019-01-00; online 2018-10-11]
PubMed DOI Crossref
Back to the drawing board-loss of chromosome Y (LOY) in leukocytes is associated with age-related macular degeneration.
Forsberg LA
Eur. J. Hum. Genet. 27 (1) 17-19 [2019-01-00; online 2018-10-23]
PubMed DOI Crossref
Affibody‑mediated imaging of EGFR expression in prostate cancer using radiocobalt‑labeled DOTA‑ZEGFR:2377.
Mitran B, Andersson KG, Lindström E, ..., Orlova A, Löfblom J
Oncol Rep 41 (1) 534-542 [2019-01-00; online 2018-10-15]
PubMed DOI Crossref
A quantitative framework for characterizing the evolutionary history of mammalian gene expression.
Chen J, Swofford R, Johnson J, ..., Palma FD, Regev A
Genome Res 29 (1) 53-63 [2019-01-00; online 2018-12-14]
DOI Crossref
Solar steam generation based on the photothermal effect: from designs to applications, and beyond
Lin Y, Xu H, Shan X, ..., Hu Y, Gan Z
J. Mater. Chem. A 7 (33) 19203-19227 [2019-00-00; online 2019-00-00]
DOI Crossref
SA98GENETIC ANALYSIS OF CADM2, A POSSIBLE LINK BETWEEN MENTAL AND PHYSICAL HEALTH
Morris J, Bailey M, Baldassarre D, ..., Smith D, Strawbridge R
Eur Neuropsychopharmacol 29 (-) S1242 [2019-00-00; online 2019-00-00]
DOI Crossref
Retinoid-Related Orphan Nuclear Receptor RORB is Required for Saltatorial Locomotion in Rabbits
Carneiro M, Vieillard J, Andrade P, ..., Kullander K, Andersson L
- - (-) - [2019-00-00; online 2019-00-00]
DOI Crossref
Next-Generation Sequencing
Wiedmann M, Carroll LM
- - (-) 376-383 [2019-00-00; online 2019-00-00]
DDLS Fellow Laura Carroll
DOI Crossref
Nanostructured Minerals and Vitamins for Food Fortification and Food Supplementation
Knijnenburg JTN, Posavec L, Teleki A
- - (-) 63-98 [2019-00-00; online 2019-00-00]
Alexandra Teleki SciLifeLab Fellow
DOI Crossref
NF1 Regulates Mesenchymal Glioblastoma Plasticity and Aggressiveness Through the AP-1 Transcription Factor FOSL1
Marques C, Unterkircher T, Kroon P, ..., Carro MS, Squatrito M
SSRN Journal - (-) - [2019-00-00; online 2019-00-00]
DOI Crossref
Mitochondrion-Related Organelles in Free-Living Protists
Leger MM, Kolísko M, Stairs CW, Simpson AGB
- - (-) 287-308 [2019-00-00; online 2019-08-10]
DOI Crossref
Latest Advances in Solving the All-Pairs Suffix Prefix Problem
Rachid M
- - (-) 174-181 [2019-00-00; online 2019-00-00]
DOI Crossref
Kinetic Analysis of Carbonic Anhydrase–Sulfonamide Inhibitor Interactions
Talibov VO, Linkuvienė V, Danielson UH, Matulis D
- - (-) 125-140 [2019-00-00; online 2019-05-22]
DOI Crossref
Helix Breaking Transition in the S4 of HCN Channel is Critical for Hyperpolarization-Dependent Gating
Kasimova MA, Tewari D, Cowgill J, ..., Delemotte L, Chanda B
SSRN Journal - (-) - [2019-00-00; online 2019-00-00]
DOI Crossref
HIGH-THROUGHPUT ANTIBODY-BASED PROFILING OF SERUM IN SCHIZOPHRENIA AND BIPOLAR DISORDER PATIENTS: AN INTEGRATIVE GENOMICS-PROTEOMICS PILOT STUDY
Papiol S, Just D, Kannaiyan N, ..., Nilsson P, Schulze T
Eur Neuropsychopharmacol 29 (-) S993-S994 [2019-00-00; online 2019-00-00]
DOI Crossref
Experimental Models of Intestinal Inflammation: Lessons from Mouse and Zebrafish
Diaz OE, Morales RA, Das S, Villablanca EJ
- - (-) 47-76 [2019-00-00; online 2019-12-20]
DOI Crossref
Chemo-enzymatic pathways toward pinene-based renewable materials
Stamm A, Tengdelius M, Schmidt B, ..., Fogelström L, Malmström E
Green Chem. 21 (10) 2720-2731 [2019-00-00; online 2019-00-00]
DOI Crossref
Assessment and Management of Risks Associated With Antibiotic Resistance in the Environment
Bengtsson-Palme J
Management of Emerging Public Health Issues and Risks: Multidisciplinary Approaches to the Changing Environment - (-) 243-263 [2019-00-00; online 2019-00-00]
DDLS Fellow Johan Bengtsson-Palme
DOI Crossref
A Systems-Based Map of Human Brain Cell-Type Enriched Genes and Malignancy-Associated Endothelial Changes
Dusart P, Hallström BM, Renne T, ..., Uhlen M, Butler L
SSRN Journal - (-) - [2019-00-00; online 2019-00-00]
SciLifeLab Data Centre
Publications 9.5.1