Publications 2019

1083 publications

The Heat Shock Response in Yeast Maintains Protein Homeostasis by Chaperoning and Replenishing Proteins.
Mühlhofer M, Berchtold E, Stratil CG, ..., Zimmer R, Buchner J
Cell Reports 29 (13) 4593-4607.e8 [2019-12-24; online 2019-12-26]
SMO-M2 mutation does not support cell-autonomous Hedgehog activity in cerebellar granule cell precursors.
Petroni M, Sahùn Roncero M, Ramponi V, ..., De Smaele E, Giannini G
Sci Rep 9 (1) 19623 [2019-12-23; online 2019-12-23]
Sex differences in clinical presentation of systemic lupus erythematosus.
Ramírez Sepúlveda JI, Bolin K, Mofors J, ..., Gunnarsson I, Wahren-Herlenius M
Biol Sex Differ 10 (1) 60 [2019-12-16; online 2019-12-16]
Lamin A/C promotes DNA base excision repair.
Maynard S, Keijzers G, Akbari M, ..., Bartek J, Bohr VA
Nucleic Acids Res. 47 (22) 11709-11728 [2019-12-16; online 2019-10-28]
Spatial mapping of cell types by integration of transcriptomics data
Andersson A, Bergenstråhle J, Asp M, ..., Navarro JF, Lundeberg J
- - (-) - [2019-12-13; online 2019-12-13]
Oral Microbiota Development in Early Childhood.
Kennedy B, Peura S, Hammar U, ..., Bertilsson S, Fall T
Sci Rep 9 (1) 19025 [2019-12-13; online 2019-12-13]
Sari Peura SciLifeLab Fellow
The influence of common polygenic risk and gene sets on social skills group training response in autism spectrum disorder
Li D, Choque-Olsson N, Jiao H, ..., Bölte S, Tammimies K
- - (-) - [2019-12-12; online 2019-12-12]
Sphingosine-1-Phosphate Receptor 1 Activity Promotes Tumor Growth by Amplifying VEGF-VEGFR2 Angiogenic Signaling.
Balaji Ragunathrao VA, Anwar M, Akhter MZ, ..., Malik AB, Mehta D
Cell Reports 29 (11) 3472-3487.e4 [2019-12-10; online 2019-12-12]
Rotational and Translational Diffusion of Proteins as a Function of Concentration.
Bashardanesh Z, Elf J, Zhang H, van der Spoel D
ACS Omega 4 (24) 20654-20664 [2019-12-10; online 2019-11-27]
A Deep Learning Framework for Predicting Response to Therapy in Cancer.
Sakellaropoulos T, Vougas K, Narang S, ..., Tsirigos A, Gorgoulis VG
Cell Reports 29 (11) 3367-3373.e4 [2019-12-10; online 2019-12-12]
Depression, GABA, and Age Correlate with Plasma Levels of Inflammatory Markers.
Bhandage AK, Cunningham JL, Jin Z, ..., Ekselius L, Birnir B
Int J Mol Sci 20 (24) - [2019-12-06; online 2019-12-06]
Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy.
Čančer M, Hutter S, Holmberg KO, ..., Weishaupt H, Swartling FJ
Cell Stem Cell 25 (6) 855-870.e11 [2019-12-05; online 2019-11-27]
High throughput barcoding method for genome-scale phasing.
Redin D, Frick T, Aghelpasand H, ..., Olsen RA, Ahmadian A
Sci Rep 9 (1) 18116 [2019-12-02; online 2019-12-02]
DNA methylation profiles in chronic lymphocytic leukemia patients treated with chemoimmunotherapy.
Tsagiopoulou M, Papakonstantinou N, Moysiadis T, ..., Rosenquist R, Stamatopoulos K
Clin Epigenetics 11 (1) 177 [2019-12-02; online 2019-12-02]
Caspase-8 modulates physiological and pathological angiogenesis during retina development.
Tisch N, Freire-Valls A, Yerbes R, ..., Augustin HG, Ruiz de Almodovar C
J. Clin. Invest. 129 (12) 5092-5107 [2019-12-02; online 2019-08-28]
Arteria: An automation system for a sequencing core facility.
Dahlberg J, Hermansson J, Sturlaugsson S, ..., Hofmann O, Larsson P
Gigascience 8 (12) - [2019-12-01; online 2019-12-12]
Aquatic Adaptation and Depleted Diversity: A Deep Dive into the Genomes of the Sea Otter and Giant Otter.
Beichman AC, Koepfli KP, Li G, ..., Lohmueller KE, Wayne RK
Mol. Biol. Evol. 36 (12) 2631-2655 [2019-12-01; online 2019-06-19]
Zebrafish embryo as a replacement model for initial biocompatibility studies of biomaterials and drug delivery systems.
Rothenbücher TSP, Ledin J, Gibbs D, ..., Persson C, Hulsart-Billström G
Acta Biomater 100 (-) 235-243 [2019-12-00; online 2019-10-01]
The genomic footprint of sexual conflict.
Sayadi A, Martinez Barrio A, Immonen E, ..., Nystedt B, Arnqvist G
Nat Ecol Evol 3 (12) 1725-1730 [2019-12-00; online 2019-11-18]
The Emergence of Life
Camprubí E, de Leeuw JW, House CH, ..., Tirumalai MR, Westall F
Space Sci Rev 215 (8) - [2019-12-00; online 2019-12-12]
Obituary: Jonas Blomberg (1944–2019)
Medstrand P, Jern P
Retrovirology 16 (1) - [2019-12-00; online 2019-03-14]
Nordic Guidelines for Germline Predisposition to Myeloid Neoplasms in Adults: Recommendations for Genetic Diagnosis, Clinical Management and Follow-up.
Baliakas P, Tesi B, Wartiovaara-Kautto U, ..., Hellström-Lindberg E, Andersen MK
Hemasphere 3 (6) e321 [2019-12-00; online 2019-11-04]
ImJoy: an open-source computational platform for the deep learning era.
Ouyang W, Mueller F, Hjelmare M, Lundberg E, Zimmer C
Nat. Methods 16 (12) 1199-1200 [2019-12-00; online 2019-11-30]
DDLS Fellow Wei Ouyang
Genetically Engineered Fd Viruses for Site Specific Material Binding
Korkmaz N, Arslan T
BioNanoSci. 9 (4) 862-872 [2019-12-00; online 2019-08-03]
Generation of human induced pluripotent stem cell lines from patients with selective IgA deficiency.
Arias-Fuenzalida J, Yu J, Du L, ..., Hammarström L, Pan-Hammarström Q
Stem Cell Res 41 (-) 101613 [2019-12-00; online 2019-10-22]
Generation of a human induced pluripotent stem cell line (PHAi003) from a primary immunodeficient patient with CD70 mutation.
Arias-Fuenzalida J, Yu J, Abolhassani H, ..., Custodio J, Pan-Hammarström Q
Stem Cell Res 41 (-) 101612 [2019-12-00; online 2019-10-25]
FGFR4 phosphorylates MST1 to confer breast cancer cells resistance to MST1/2-dependent apoptosis.
Turunen SP, von Nandelstadh P, Öhman T, ..., Varjosalo M, Lehti K
Cell Death Differ. 26 (12) 2577-2593 [2019-12-00; online 2019-03-22]
Estimation of model accuracy in CASP13.
Cheng J, Choe MH, Elofsson A, ..., Venclovas Č, Wallner B
Proteins 87 (12) 1361-1377 [2019-12-00; online 2019-07-16]
Enrichment of oral microbiota in early cystic precursors to invasive pancreatic cancer.
Gaiser RA, Halimi A, Alkharaan H, ..., Del Chiaro M, Sällberg Chen M
Gut 68 (12) 2186-2194 [2019-12-00; online 2019-03-14]
DDLS Fellow Luisa Hugerth
Comparative Genomics Reveals Shared Mutational Landscape in Canine Hemangiosarcoma and Human Angiosarcoma.
Megquier K, Turner-Maier J, Swofford R, ..., Elvers I, Lindblad-Toh K
Mol. Cancer Res. 17 (12) 2410-2421 [2019-12-00; online 2019-09-30]
Analytic approach to explore dynamical osteoporotic bone turnover
Javed S, Younas M, Bhatti MY, Sohail A, Sattar A
Adv Differ Equ 2019 (1) - [2019-12-00; online 2019-02-14]
A miR-206 regulated gene landscape enhances mammary epithelial differentiation.
Wang J, Aydoğdu E, Mukhopadhyay S, Helguero LA, Williams C
J. Cell. Physiol. 234 (12) 22220-22233 [2019-12-00; online 2019-05-08]
Chemical flexibility of heterobimetallic Mn/Fe cofactors: R2lox and R2c proteins.
Kutin Y, Kositzki R, Branca RMM, ..., Cox N, Griese JJ
J Biol Chem 294 (48) 18372-18386 [2019-11-29; online 2019-10-07]
TcellSubC: An Atlas of the Subcellular Proteome of Human T Cells.
Joshi RN, Stadler C, Lehmann R, ..., Schmidt A, Vesterlund M
Front Immunol 10 (-) 2708 [2019-11-26; online 2019-11-26]
WRNIP1 Protects Reversed DNA Replication Forks from SLX4-Dependent Nucleolytic Cleavage.
Porebski B, Wild S, Kummer S, ..., Gaillard PL, Gari K
iScience 21 (-) 31-41 [2019-11-22; online 2019-10-08]
MYCN-enhanced Oxidative and Glycolytic Metabolism Reveals Vulnerabilities for Targeting Neuroblastoma.
Oliynyk G, Ruiz-Pérez MV, Sainero-Alcolado L, ..., Lehtiö J, Arsenian-Henriksson M
iScience 21 (-) 188-204 [2019-11-22; online 2019-10-11]
The population genomics of structural variation in a songbird genus
Weissensteiner MH, Bunikis I, Catalán A, ..., Warmuth VM, Wolf JBW
- - (-) - [2019-11-18; online 2019-11-18]
Olfactory Learning in the Stingless Bee Melipona eburnea Friese (Apidae: Meliponini).
Amaya-Márquez M, Tusso S, Hernández J, ..., Wells H, I Abramson C
Insects 10 (11) - [2019-11-18; online 2019-11-18]
Human Origins in Southern African Palaeo-wetlands? Strong Claims from Weak Evidence
Schlebusch CM, Loog L, Groucutt HS, ..., Brierley C, Thomas MG
- - (-) - [2019-11-17; online 2019-11-17]
High-Throughput Functional Ex-Vivo Drug Testing and Multi-Omics Profiling in Patients with Acute Myeloid Leukemia
Erkers T, Seashore-Ludlow B, Struyf N, ..., Lehtiö J, Kallioniemi O
Blood 134 (Supplement_1) 4641-4641 [2019-11-13; online 2019-11-13]
Single-Cell Transcriptomics Uncovers Zonation of Function in the Mesenchyme during Liver Fibrosis.
Dobie R, Wilson-Kanamori JR, Henderson BEP, ..., Marioni JC, Henderson NC
Cell Reports 29 (7) 1832-1847.e8 [2019-11-12; online 2019-11-14]
NF1 regulates mesenchymal glioblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1
Marques C, Unterkircher T, Kroon P, ..., Carro MS, Squatrito M
- - (-) - [2019-11-07; online 2019-11-07]
Agonist Selectivity and Ion Permeation in the α3β4 Ganglionic Nicotinic Receptor.
Gharpure A, Teng J, Zhuang Y, ..., Lindahl E, Hibbs RE
Neuron 104 (3) 501-511.e6 [2019-11-06; online 2019-09-02]
Myc-dependent endothelial proliferation is controlled by phosphotyrosine 1212 in VEGF receptor-2.
Testini C, Smith RO, Jin Y, ..., Hellström M, Claesson-Welsh L
EMBO Rep. 20 (11) e47845 [2019-11-05; online 2019-09-23]
A Systems-Based Map of Human Brain Cell-Type Enriched Genes and Malignancy-Associated Endothelial Changes.
Dusart P, Hallström BM, Renné T, ..., Uhlén M, Butler LM
Cell Reports 29 (6) 1690-1706.e4 [2019-11-05; online 2019-11-07]
Switched reaction specificity in polyesterases towards amide bond hydrolysis by enzyme engineering.
Biundo A, Subagia R, Maurer M, ..., Syrén PO, Guebitz GM
RSC Adv. 9 (62) 36217-36226 [2019-11-04; online 2019-11-07]
Fibrin fragment E potentiates TGF-β-induced myofibroblast activation and recruitment
Fuchs PF, Heindryckx F, Calitz C, ..., Kreuger J, Gerwins P
- - (-) - [2019-11-04; online 2019-11-04]
eIF4A inhibition circumvents uncontrolled DNA replication mediated by 4E-BP1 loss in pancreatic cancer.
Müller D, Shin S, Goullet de Rugy T, ..., Pyronnet S, Martineau Y
JCI Insight 4 (21) - [2019-11-01; online 2019-11-01]
Author Correction: Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells.
Page BDG, Valerie NCK, Wright RHG, ..., Beato M, Helleday T
Nat Commun 10 (1) 5050 [2019-11-01; online 2019-11-01]
Novel non-classic CYP21A2 variants, including combined alleles, identified in patients with congenital adrenal hyperplasia.
Karlsson L, de Paula Michelatto D, Lusa ALG, ..., Barbaro M, Lajic S
Clin Biochem 73 (-) 50-56 [2019-11-00; online 2019-07-22]
Mesenchymal transition and increased therapy resistance of glioblastoma cells is related to astrocyte reactivity.
Niklasson M, Bergström T, Jarvius M, ..., Segerman B, Segerman A
J. Pathol. 249 (3) 295-307 [2019-11-00; online 2019-08-31]
Leveraging European infrastructures to access 1 million human genomes by 2022.
Saunders G, Baudis M, Becker R, ..., Blomberg N, Scollen S
Nat. Rev. Genet. 20 (11) 693-701 [2019-11-00; online 2019-08-27]
Genetic predisposition to mosaic Y chromosome loss in blood.
Thompson DJ, Genovese G, Halvardson J, ..., Forsberg LA, Perry JRB
Nature 575 (7784) 652-657 [2019-11-00; online 2019-11-20]
Diagnostic pitfalls in vitamin B6-dependent epilepsy caused by mutations in the PLPBP gene.
Jensen KV, Frid M, Stödberg T, ..., Darin N, Grønborg S
JIMD Rep 50 (1) 1-8 [2019-11-00; online 2019-09-30]
CDX2 Loss With Microsatellite Stable Phenotype Predicts Poor Clinical Outcome in Stage II Colorectal Carcinoma.
Slik K, Turkki R, Carpén O, ..., Sundström J, Pellinen T
Am J Surg Pathol 43 (11) 1473-1482 [2019-11-00; online 2019-09-07]
Astakine1 forms protein complex in plasma.
Sirikharin R, Noonin C, Junkunlo K, Söderhäll K, Söderhäll I
Fish Shellfish Immunol. 94 (-) 66-71 [2019-11-00; online 2019-08-26]
Association of PTHrP levels in CSF with Alzheimer's disease biomarkers.
Kushnir MM, Michno W, Rockwood AL, ..., Strathmann FG, Hanrieder J
Clin Mass Spectrom 14 Pt B (-) 124-129 [2019-11-00; online 2018-10-09]
SciLifeLab Fellow Wojciech Michno
Apis mellifera.
Webster MT
Trends in Genetics 35 (11) 880-881 [2019-11-00; online 2019-10-09]
ADAMDEC1 Maintains a Growth Factor Signaling Loop in Cancer Stem Cells.
Jimenez-Pascual A, Hale JS, Kordowski A, ..., Lathia JD, Siebzehnrubl FA
Cancer Discov 9 (11) 1574-1589 [2019-11-00; online 2019-08-21]
The role of ligand-gated conformational changes in enzyme catalysis.
Moreira C, Calixto AR, Richard JP, Kamerlin SCL
Biochem. Soc. Trans. 47 (5) 1449-1460 [2019-10-31; online 2019-10-28]
The architecture of the Plasmodiophora brassicae nuclear and mitochondrial genomes.
Stjelja S, Fogelqvist J, Tellgren-Roth C, Dixelius C
Sci Rep 9 (1) 15753 [2019-10-31; online 2019-10-31]
STATegra, a comprehensive multi-omics dataset of B-cell differentiation in mouse.
Gomez-Cabrero D, Tarazona S, Ferreirós-Vidal I, ..., Tegner J, Conesa A
Sci Data 6 (1) 256 [2019-10-31; online 2019-10-31]
Population structure of drug-resistant Mycobacterium tuberculosis in Central Asia.
Engström A, Antonenka U, Kadyrov A, ..., Niemann S, Hoffmann H
BMC Infect Dis 19 (1) 908 [2019-10-29; online 2019-10-29]
Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9.
Schmidt AF, Holmes MV, Preiss D, ..., Casas JP, Hingorani AD
BMC Cardiovasc Disord 19 (1) 240 [2019-10-29; online 2019-10-29]
High-Grade Progression Confers Poor Survival in Pancreatic Neuroendocrine Tumors.
Botling J, Lamarca A, Bajic D, ..., Skogseid B, Crona J
Neuroendocrinology 110 (11-12) 891-898 [2019-10-29; online 2019-10-29]
Sharing Data from Molecular Simulations.
Abraham M, Apostolov R, Barnoud J, ..., Woods C, Zhmurov A
J Chem Inf Model 59 (10) 4093-4099 [2019-10-28; online 2019-10-11]
Lucie Delemotte SciLifeLab Fellow
Domainoid: domain-oriented orthology inference.
Persson E, Kaduk M, Forslund SK, Sonnhammer ELL
BMC Bioinformatics 20 (1) 523 [2019-10-28; online 2019-10-28]
Liver X Receptor regulates Th17 and RORγt + Treg cells by distinct mechanisms
Parigi SM, Das S, Frede A, ..., Gustafsson JÅ, Villablanca EJ
- - (-) - [2019-10-25; online 2019-10-25]
Detection of a High-Turnover Serotonin Circuit in the Mouse Brain Using Mass Spectrometry Imaging.
Sugiyama E, Guerrini MM, Honda K, ..., Suematsu M, Sugiura Y
iScience 20 (-) 359-372 [2019-10-25; online 2019-09-27]
Detailed Functional Characterization of a Waist-Hip Ratio Locus in 7p15.2 Defines an Enhancer Controlling Adipocyte Differentiation.
Castillejo-Lopez C, Pjanic M, Pirona AC, ..., Arner E, Ingelsson E
iScience 20 (-) 42-59 [2019-10-25; online 2019-09-10]
Colibactin DNA damage signature indicates causative role in colorectal cancer
Dziubańska-Kusibab PJ, Berger H, Battistini F, ..., Aaltonen LA, Meyer TF
- - (-) - [2019-10-25; online 2019-10-25]
ClinGen Myeloid Malignancy Variant Curation Expert Panel recommendations for germline RUNX1 variants.
Luo X, Feurstein S, Mohan S, ..., Wu D, Godley LA
Blood Adv 3 (20) 2962-2979 [2019-10-22; online 2019-10-28]
Phagocytosis is mediated by two-dimensional assemblies of the F-BAR protein GAS7.
Hanawa-Suetsugu K, Itoh Y, Ab Fatah M, ..., Shimada A, Suetsugu S
Nat Commun 10 (1) 4763 [2019-10-18; online 2019-10-18]
Considerations and Implications in the Purification of Extracellular Vesicles - A Cautionary Tale.
Lee YXF, Johansson H, Wood MJA, El Andaloussi S
Front Neurosci 13 (-) 1067 [2019-10-18; online 2019-10-18]
NOX4 regulates TGFβ-induced proliferation and self-renewal in glioblastoma stem cells
García-Gómez P, Dadras M, Bellomo C, ..., Moren A, Caja L
- - (-) - [2019-10-15; online 2019-10-15]
Cathepsin g degrades synovial fluid lubricin: relevance for osteoarthritis pathogenesis
Huang S, Thomsson KA, Jin C, ..., Karlsson NG, Eisler T
- - (-) - [2019-10-15; online 2019-10-15]
An intrinsically disordered proteins community for ELIXIR.
Davey NE, Babu MM, Blackledge M, ..., Wichapong K, Tosatto SCE
F1000Res 8 (-) - [2019-10-15; online 2019-10-15]
Activation of Oncogenic Super-Enhancers Is Coupled with DNA Repair by RAD51.
Hazan I, Monin J, Bouwman BAM, Crosetto N, Aqeilan RI
Cell Reports 29 (3) 560-572.e4 [2019-10-15; online 2019-10-17]
Affinity‐Based Chemoproteomics for Target Identification
Jenmalm Jensen A, Cornella Taracido I
- - (-) 25-49 [2019-10-14; online 2019-12-13]
N-Trifluoromethylthiolated Sulfonimidamides and Sulfoximines: Anti-microbial, Anti-mycobacterial, and Cytotoxic Activity.
Thota N, Makam P, Rajbongshi KK, ..., Naicker T, Arvidsson PI
ACS Med. Chem. Lett. 10 (10) 1457-1461 [2019-10-10; online 2019-09-11]
Reduced sialyl-Lewisx on salivary MUC7 from patients with burning mouth syndrome.
Acharya S, Jin C, Bylund J, ..., Carlén A, Karlsson NG
Mol Omics 15 (5) 331-339 [2019-10-07; online 2019-08-16]
MetaCNV - a consensus approach to infer accurate copy numbers from low coverage data
Friedrich S, Barbulescu R, Helleday T, Sonnhammer EL
- - (-) - [2019-10-07; online 2019-10-07]
Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation
Ng NHJ, Willems SM, Fernandez J, ..., Gloyn AL, Barroso I
- - (-) - [2019-10-03; online 2019-10-03]
P4493Microvesicles from patients with pulmonary arterial hypertension modulate bFGF from endothelial cells
Aberg M, Khandagale A, Wikstrom G, Siegbahn A, Christersson C
Eur. Heart J. 40 (Supplement_1) - [2019-10-01; online 2019-10-21]
Nephromyces Represents a Diverse and Novel Lineage of the Apicomplexa That Has Retained Apicoplasts.
Muñoz-Gómez SA, Durnin K, Eme L, ..., Saffo MB, Slamovits CH
Genome Biol Evol 11 (10) 2727-2740 [2019-10-01; online 2019-07-23]
Dysregulation of the Tryptophan Pathway Evidences Gender Differences in COPD.
Naz S, Bhat M, Ståhl S, ..., Wheelock ÅM, Wheelock CE
Metabolites 9 (10) - [2019-10-01; online 2019-10-01]
Dissecting the Effects of Selection and Mutation on Genetic Diversity in Three Wood White (Leptidea) Butterfly Species.
Talla V, Soler L, Kawakami T, ..., Wiklund C, Backström N
Genome Biol Evol 11 (10) 2875-2886 [2019-10-01; online 2019-10-04]
Advances and Applications in the Quest for Orthologs.
Glover N, Dessimoz C, Ebersberger I, ..., Sonnhammer E, Thomas PD
Mol. Biol. Evol. 36 (10) 2157-2164 [2019-10-01; online 2019-06-27]
Voices in methods development.
Anikeeva P, Boyden E, Brangwynne C, ..., Zernicka-Goetz M, Zhuang X
Nat. Methods 16 (10) 945-951 [2019-10-00; online 2019-09-29]
Proteomics identifies neddylation as a potential therapy target in small intestinal neuroendocrine tumors.
Fotouhi O, Kjellin H, Juhlin CC, ..., Larsson C, Orre LM
Oncogene 38 (43) 6881-6897 [2019-10-00; online 2019-08-12]
P2.01-66 Genomic Landscapes of DNA Copy Number Alterations in Primary Lung Cancers and Matched Brain Metastases
Nicoś M, Garnerone S, Harbers L, ..., Jassem J, Crosetto N
Journal of Thoracic Oncology 14 (10) S665-S666 [2019-10-00; online 2019-10-00]
Inhibition of SYK or BTK augments venetoclax sensitivity in SHP1-negative/BCL-2-positive diffuse large B-cell lymphoma.
Sasi BK, Martines C, Xerxa E, ..., Rosenquist R, Efremov DG
Leukemia 33 (10) 2416-2428 [2019-10-00; online 2019-03-14]
Duration of use of proton pump inhibitors and the risk of gastric and oesophageal cancer.
Brusselaers N, Lagergren J, Engstrand L
Cancer Epidemiol 62 (-) 101585 [2019-10-00; online 2019-08-21]
Dog Ownership and Survival After a Major Cardiovascular Event: A Register-Based Prospective Study.
Mubanga M, Byberg L, Egenvall A, Ingelsson E, Fall T
Circ Cardiovasc Qual Outcomes 12 (10) e005342 [2019-10-00; online 2019-10-08]
Disulfiram's anti-cancer activity reflects targeting NPL4, not inhibition of aldehyde dehydrogenase.
Skrott Z, Majera D, Gursky J, ..., Mistrik M, Bartek J
Oncogene 38 (40) 6711-6722 [2019-10-00; online 2019-08-07]
An Empirical Study of the Relation Between Network Architecture and Complexity
Konuk E, Smith K
- - (-) 4597-4599 [2019-10-00; online 2019-10-00]
Acute Cocaine Enhances Dopamine D2R Recognition and Signaling and Counteracts D2R Internalization in Sigma1R-D2R Heteroreceptor Complexes.
Borroto-Escuela DO, Narváez M, Romero-Fernández W, ..., Ferraro L, Fuxe K
Mol. Neurobiol. 56 (10) 7045-7055 [2019-10-00; online 2019-04-10]
Interactions between Toll-Like Receptor 4 (TLR4) polymorphisms and urban or rural living on the risk for Asthma
Kisiel M, Rask-Andersen M, Johansson Å, Ek W, Rask-Andersen A
- - (-) PA1977 [2019-09-28; online 2019-11-21]
Molecular Atlas of the Adult Mouse Brain
Ortiz C, Navarro JF, Jurek A, ..., Lundeberg J, Meletis K
- - (-) - [2019-09-27; online 2019-09-27]
Homogeneous Differential Magnetic Assay.
Sepehri S, Zardán Gómez de la Torre T, Schneiderman JF, ..., Winkler D, Kalaboukhov A
ACS Sens 4 (9) 2381-2388 [2019-09-27; online 2019-08-22]
An Algorithmic Information Calculus for Causal Discovery and Reprogramming Systems.
Zenil H, Kiani NA, Marabita F, ..., Ball G, Tegnér J
iScience 19 (-) 1160-1172 [2019-09-27; online 2019-08-08]
An efficient single-cell transcriptomics workflow to assess protist diversity and lifestyle
Onsbring H, Tice AK, Barton BT, Brown MW, Ettema TJG
- - (-) - [2019-09-25; online 2019-09-25]
Novel Y-Chromosome Long Non-Coding RNAs Expressed in Human Male CNS During Early Development.
Johansson MM, Pottmeier P, Suciu P, ..., Peuckert C, Jazin E
Front Genet 10 (-) 891 [2019-09-24; online 2019-09-24]
Multi-HLA class II tetramer analyses of citrulline-reactive T cells and early treatment response in rheumatoid arthritis
Gerstner C, Turcinov S, Hensvold AH, ..., Baarsen LGMv, Malmström V
- - (-) - [2019-09-24; online 2019-09-24]
Identification and Characterization of Post-activated B Cells in Systemic Autoimmune Diseases.
Weißenberg SY, Szelinski F, Schrezenmeier E, ..., Lino AC, Dörner T
Front Immunol 10 (-) 2136 [2019-09-24; online 2019-09-24]
Ataxia in Patients With Bi-Allelic NFASC Mutations and Absence of Full-Length NF186.
Kvarnung M, Shahsavani M, Taylan F, ..., Lindstrand A, Falk A
Front Genet 10 (-) 896 [2019-09-24; online 2019-09-24]
The Complement System Is Essential for the Phagocytosis of Mesenchymal Stromal Cells by Monocytes.
Gavin C, Meinke S, Heldring N, ..., Le Blanc K, Kadri N
Front Immunol 10 (-) 2249 [2019-09-20; online 2019-09-20]
The Stapled Peptide PM2 Stabilizes p53 Levels and Radiosensitizes Wild-Type p53 Cancer Cells.
Mortensen ACL, Spiegelberg D, Brown CJ, Lane DP, Nestor M
Front Oncol 9 (-) 923 [2019-09-19; online 2019-09-19]
The TGFB2-AS1 lncRNA Regulates TGF-β Signaling by Modulating Corepressor Activity.
Papoutsoglou P, Tsubakihara Y, Caja L, ..., Heldin CH, Moustakas A
Cell Reports 28 (12) 3182-3198.e11 [2019-09-17; online 2019-09-19]
eBDIMS server: protein transition pathways with ensemble analysis in 2D-motion spaces.
Orellana L, Gustavsson J, Bergh C, Yoluk O, Lindahl E
Bioinformatics 35 (18) 3505-3507 [2019-09-15; online 2019-03-07]
Heparanase promotes glioma progression via enhancing CD24 expression.
Barash U, Spyrou A, Liu P, ..., Vlodavsky I, Yang X
Int. J. Cancer 145 (6) 1596-1608 [2019-09-15; online 2019-05-14]
Batch-normalization of cerebellar and medulloblastoma gene expression datasets utilizing empirically defined negative control genes.
Weishaupt H, Johansson P, Sundström A, ..., Nelander S, Swartling FJ
Bioinformatics 35 (18) 3357-3364 [2019-09-15; online 2019-02-05]
A Single-Stranded Oligonucleotide Inhibits Toll-Like Receptor 3 Activation and Reduces Influenza A (H1N1) Infection.
Poux C, Dondalska A, Bergenstråhle J, ..., Tregoning JS, Spetz AL
Front Immunol 10 (-) 2161 [2019-09-12; online 2019-09-12]
Sharing Data from Molecular Simulations
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Speeding Up Percolator.
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Identification of a Biomarker Panel for Early Detection of Lung Cancer Patients.
Geary B, Walker MJ, Snow JT, ..., Crosbie PA, Whetton AD
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Splotch: Robust estimation of aligned spatial temporal gene expression data
Äijö T, Maniatis S, Vickovic S, ..., Lundeberg J, Bonneau R
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Sanja Vickovic SciLifeLab Fellow
Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis.
Huang M, Tailor J, Zhen Q, ..., Smith A, Weiss WA
Cell Stem Cell 25 (3) 433-446.e7 [2019-09-05; online 2019-06-13]
Unveiling the Biochemistry of the Epigenetic Regulator SMYD3.
Fabini E, Talibov VO, Mihalic F, ..., Del Rio A, Danielson UH
Biochemistry 58 (35) 3634-3645 [2019-09-03; online 2019-08-21]
NK cells switch from granzyme B to death receptor-mediated cytotoxicity during serial killing.
Prager I, Liesche C, van Ooijen H, ..., Önfelt B, Watzl C
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The autoantibody response to cyclic citrullinated collagen type II peptides in rheumatoid arthritis.
Liang B, Ge C, Lönnblom E, ..., Zhao M, Holmdahl R
Rheumatology (Oxford) 58 (9) 1623-1633 [2019-09-01; online 2019-03-21]
Impact of Epithelial-Stromal Interactions on Peritumoral Fibroblasts in Ductal Carcinoma in Situ.
Strell C, Paulsson J, Jin SB, ..., Wärnberg F, Östman A
J. Natl. Cancer Inst. 111 (9) 983-995 [2019-09-01; online 2019-03-01]
Salmonella persisters promote the spread of antibiotic resistance plasmids in the gut.
Bakkeren E, Huisman JS, Fattinger SA, ..., Diard M, Hardt WD
Nature 573 (7773) 276-280 [2019-09-00; online 2019-09-04]
Mikael Sellin SciLifeLab Fellow
Regulation of replication fork speed: Mechanisms and impact on genomic stability.
Merchut-Maya JM, Bartek J, Maya-Mendoza A
DNA Repair (Amst.) 81 (-) 102654 [2019-09-00; online 2019-07-08]
Real-time prediction of influenza outbreaks in Belgium.
Miranda GHB, Baetens JM, Bossuyt N, Bruno OM, De Baets B
Epidemics 28 (-) 100341 [2019-09-00; online 2019-04-18]
Gisele Miranda SciLifeLab Fellow
Prescribed Drugs and the Microbiome.
Brusselaers N
Gastroenterol Clin North Am 48 (3) 331-342 [2019-09-00; online 2019-06-12]
Mitochondrial DNA analysis of a Viking age mass grave in Sweden.
Buś MM, Lembring M, Kjellström A, ..., Parson W, Allen M
Forensic Sci Int Genet 42 (-) 268-274 [2019-09-00; online 2019-06-06]
Microfluidic Immunoaffinity Basophil Activation Test for Point-of-Care Allergy Diagnosis.
Aljadi Z, Kalm F, Ramachandraiah H, ..., Lundahl J, Russom A
J Appl Lab Med 4 (2) 152-163 [2019-09-00; online 2019-05-09]
Introducing the HPA Brain Atlas, a brain-centric sub atlas with regional expression maps of the human, mouse and pig brain
Sjöstedt E, Zhong W, Mitsios N, ..., Ulhén M, Mulder J
IBRO Reports 6 (-) S526 [2019-09-00; online 2019-09-00]
Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration.
Wilman HR, Parisinos CA, Atabaki-Pasdar N, ..., Banerjee R, Yaghootkar H
J Hepatol 71 (3) 594-602 [2019-09-00; online 2019-06-19]
Fibroblast as a critical stromal cell type determining prognosis in prostate cancer.
Blom S, Erickson A, Östman A, ..., Kallioniemi O, Pellinen T
Prostate 79 (13) 1505-1513 [2019-09-00; online 2019-07-03]
A genome-wide transcriptional study reveals that iron deficiency inhibits the yeast TORC1 pathway.
Romero AM, Ramos-Alonso L, Montellá-Manuel S, ..., Martínez-Pastor MT, Puig S
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1862 (9) 194414 [2019-09-00; online 2019-08-05]
Prototypical pacemaker neurons are immunocompetent cells
Klimovich A, Giacomello S, Björklund Å, ..., Adameyko I, Bosch TCG
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A Bi-LSTM Based Ensemble Algorithm for Prediction of Protein Secondary Structure
Hu H, Li Z, Elofsson A, Xie S
Applied Sciences 9 (17) 3538 [2019-08-28; online 2019-08-28]
Small-Molecule and CRISPR Screening Converge to Reveal Receptor Tyrosine Kinase Dependencies in Pediatric Rhabdoid Tumors.
Oberlick EM, Rees MG, Seashore-Ludlow B, ..., Schreiber SL, Roberts CWM
Cell Reports 28 (9) 2331-2344.e8 [2019-08-27; online 2019-08-29]
Prediction of Partition Coefficients of Environmental Toxins Using Computational Chemistry Methods.
van der Spoel D, Manzetti S, Zhang H, Klamt A
ACS Omega 4 (9) 13772-13781 [2019-08-27; online 2019-08-12]
Nanoscale dynamics of cholesterol in the cell membrane.
Pinkwart K, Schneider F, Lukoseviciute M, ..., Eggeling C, Sezgin E
J. Biol. Chem. 294 (34) 12599-12609 [2019-08-23; online 2019-07-03]
Erdinc Sezgin SciLifeLab Fellow
Karonudib is a promising anticancer therapy in hepatocellular carcinoma.
Hua X, Sanjiv K, Gad H, ..., Helleday T, Warpman Berglund U
Ther Adv Med Oncol 11 (-) 1758835919866960 [2019-08-23; online 2019-08-23]
Array-Based Profiling of Proteins and Autoantibody Repertoires in CSF.
Pin E, Sjöberg R, Andersson E, ..., Nilsson P, Månberg A
Methods in molecular biology (Clifton, N.J.) 2044 (-) 303-318 [2019-08-23; online 2019-08-23]
Restriction of AID activity and somatic hypermutation by PARP-1.
Tepper S, Mortusewicz O, Członka E, ..., Leonhardt H, Jungnickel B
Nucleic Acids Res. 47 (14) 7418-7429 [2019-08-22; online 2019-05-28]
Editorial: Technical Advances in Cryo-Electron Microscopy.
Rivera-Calzada A, Carroni M
Front Mol Biosci 6 (-) 72 [2019-08-22; online 2019-08-22]
Exhaustion of CD4+ T-cells mediated by the Kynurenine Pathway in Melanoma.
Rad Pour S, Morikawa H, Kiani NA, ..., Hansson J, Tegnér J
Sci Rep 9 (1) 12150 [2019-08-21; online 2019-08-21]
Toxic Activation of an AAA+ Protease by the Antibacterial Drug Cyclomarin A.
Maurer M, Linder D, Franke KB, ..., Bukau B, Mogk A
Cell Chem Biol 26 (8) 1169-1179.e4 [2019-08-15; online 2019-06-13]
DNA Methylation Trajectories During Pregnancy.
Gruzieva O, Merid SK, Chen S, ..., Arshad SH, Pershagen G
Epigenet Insights 12 (-) 2516865719867090 [2019-08-13; online 2019-08-13]
The bio.tools registry of software tools and data resources for the life sciences.
Ison J, Ienasescu H, Chmura P, ..., Løngreen P, Brunak S
Genome Biol. 20 (1) 164 [2019-08-12; online 2019-08-12]
Spatial and temporal transcriptomics reveal microglia-astroglia crosstalk in the amyloid-β plaque cell niche of Alzheimer’s disease
Chen WT, Lu A, Craessaerts K, ..., Fiers M, De Strooper B
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Detecting and Controlling Dye Effects in Single-Virus Fusion Experiments.
Rawle RJ, Villamil Giraldo AM, Boxer SG, Kasson PM
Biophys. J. 117 (3) 445-452 [2019-08-06; online 2019-07-02]
Single Cell Gene Expression Analysis Reveals Human Stem Cell-Derived Graft Composition in a Cell Therapy Model of Parkinson’s Disease
Tiklová K, Nolbrant S, Fiorenzano A, ..., Perlmann T, Parmar M
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Social Parasitism in the Honeybee (Apis mellifera) Is Not Controlled by a Single SNP.
Christmas MJ, Smith NMA, Oldroyd BP, Webster MT
Mol. Biol. Evol. 36 (8) 1764-1767 [2019-08-01; online 2019-04-28]
PconsC4: fast, accurate and hassle-free contact predictions.
Michel M, Menéndez Hurtado D, Elofsson A
Bioinformatics 35 (15) 2677-2679 [2019-08-01; online 2018-12-28]
Intraspecific Diversity of Fission Yeast Mitochondrial Genomes.
Tao YT, Suo F, Tusso S, ..., Wolf JBW, Du LL
Genome Biol Evol 11 (8) 2312-2329 [2019-08-01; online 2019-08-01]
Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells.
Amaral PP, Engström PG, Robson SC, ..., Kouzarides T, Castelo-Branco G
Exp. Cell Res. 381 (1) 129-138 [2019-08-01; online 2019-05-09]
Tools for Bioimaging Pancreatic β Cells in Diabetes.
Kang NY, Soetedjo AAP, Amirruddin NS, ..., Eriksson O, Teo AKK
Trends in molecular medicine 25 (8) 708-722 [2019-08-00; online 2019-06-06]
Olof Eriksson SciLifeLab Fellow
The metabolites urobilin and sphingomyelin (30:1) are associated with incident heart failure in the general population.
Stenemo M, Ganna A, Salihovic S, ..., Ärnlöv J, Fall T
ESC Heart Fail 6 (4) 764-773 [2019-08-00; online 2019-05-30]
Systematic Development of Sandwich Immunoassays for the Plasma Secretome.
Häussler RS, Bendes A, Iglesias M, ..., Qundos U, Schwenk JM
Proteomics 19 (15) e1900008 [2019-08-00; online 2019-07-22]
DDLS Fellow Fredrik Edfors
Short- and long-term effect of contraceptive methods on fecundity.
Berglund Scherwitzl E, Lundberg O, Kopp Kallner H, ..., Gemzell Danielsson K, Scherwitzl R
Eur J Contracept Reprod Health Care 24 (4) 260-265 [2019-08-00; online 2019-06-21]
Phosphatase inhibitor PPP1R11 modulates resistance of human T cells toward Treg-mediated suppression of cytokine expression.
Joshi RN, Fernandes SJ, Shang MM, ..., Tegnér J, Schmidt A
J Leukoc Biol 106 (2) 413-430 [2019-08-00; online 2019-03-18]
Moritella viscosa in lumpfish (Cyclopterus lumpus) and Atlantic salmon (Salmo salar)
Einarsdottir T, Sigurdardottir H, Einarsdottir E, Bjornsdottir TS
Fish Shellfish Immunol. 91 (-) 469 [2019-08-00; online 2019-08-00]
Gas-Phase Collisions with Trimethylamine-N-Oxide Enable Activation-Controlled Protein Ion Charge Reduction.
Kaldmäe M, Österlund N, Lianoudaki D, ..., Marklund EG, Landreh M
J. Am. Soc. Mass Spectrom. 30 (8) 1385-1388 [2019-08-00; online 2019-07-08]
Functional characterization in vitro of twelve naturally occurring variants of the human pancreatic polypeptide receptor NPY4R.
Shebanits K, Vasile S, Xu B, Gutiérrez-de-Terán H, Larhammar D
Neuropeptides 76 (-) 101933 [2019-08-00; online 2019-05-15]
Breast cancer outcome prediction with tumour tissue images and machine learning.
Turkki R, Byckhov D, Lundin M, ..., Lundin J, Linder N
Breast Cancer Res. Treat. 177 (1) 41-52 [2019-08-00; online 2019-05-22]
An archaeal symbiont-host association from the deep terrestrial subsurface.
Schwank K, Bornemann TLV, Dombrowski N, ..., Banfield JF, Probst AJ
ISME J 13 (8) 2135-2139 [2019-08-00; online 2019-05-02]
Computational and Experimental Druggability Assessment of Human DNA Glycosylases.
Michel M, Visnes T, Homan EJ, ..., Warpman Berglund U, Helleday T
ACS Omega 4 (7) 11642-11656 [2019-07-31; online 2019-07-05]
Shared and Unique Patterns of DNA Methylation in Systemic Lupus Erythematosus and Primary Sjögren's Syndrome.
Imgenberg-Kreuz J, Almlöf JC, Leonard D, ..., Sandling JK, Nordmark G
Front Immunol 10 (-) 1686 [2019-07-30; online 2019-07-30]
Amyloid fibril polymorphism and cell-specific toxicity in vivo.
Jonson M, Nyström S, Sandberg A, ..., Thor S, Hammarström P
Amyloid 26 (sup1) 136-137 [2019-07-26; online 2019-07-26]
SciLifeLab Fellow Wojciech Michno
Spatial Chromosome Folding and Active Transcription Drive DNA Fragility and Formation of Oncogenic MLL Translocations.
Gothe HJ, Bouwman BAM, Gusmao EG, ..., Crosetto N, Roukos V
Mol. Cell 75 (2) 267-283.e12 [2019-07-25; online 2019-06-12]
Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis.
Smillie CS, Biton M, Ordovas-Montanes J, ..., Xavier RJ, Regev A
Cell 178 (3) 714-730.e22 [2019-07-25; online 2019-07-28]
Sanja Vickovic SciLifeLab Fellow
Estrogen deprivation triggers an immunosuppressive phenotype in breast cancer cells
Hühn D, Martí-Rodrigo P, Mouron S, ..., Carreras-Puigvert J, Fernandez-Capetillo O
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Structure of McrBC without DNA binding domains (one half of the full complex)
Itoh Y, Nirwan N, Saikrishnan K, Amunts A
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A collagen-based microwell migration assay to study NK-target cell interactions.
Olofsson PE, Brandt L, Magnusson KEG, ..., Jaldén J, Önfelt B
Sci Rep 9 (1) 10672 [2019-07-23; online 2019-07-23]
Caspase-8 Modulates Angiogenesis By Regulating A Cell Death Independent Pathway In Endothelial Cells
Tisch N, Freire-Valls A, Yerbes R, ..., Augustin HG, de Almodovar CR
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Population genomics of the Viking world
Margaryan A, Lawson D, Sikora M, ..., Werge T, Willerslev E
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A Chemical Screen Identifies Compounds Capable of Selecting for Haploidy in Mammalian Cells.
Olbrich T, Vega-Sendino M, Murga M, ..., Ruiz S, Fernandez-Capetillo O
Cell Reports 28 (3) 597-604.e4 [2019-07-16; online 2019-07-18]
The Potential Use of Metabolic Cofactors in Treatment of NAFLD.
Mardinoglu A, Ural D, Zeybel M, ..., Uhlén M, Borén J
Nutrients 11 (7) 1578 [2019-07-12; online 2019-07-12]
Adil Mardinoglu SciLifeLab Fellow
Sexual dimorphism in the incidence of human cancers.
Zheng D, Trynda J, Williams C, ..., McLaughlin SA, Li Z
BMC Cancer 19 (1) 684 [2019-07-12; online 2019-07-12]
Mozambican genetic variation provides new insights into the Bantu expansion
Semo A, Gayà-Vidal M, Fortes-Lima C, ..., Schlebusch C, Rocha J
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The role of gelsolin domain 3 in familial amyloidosis (Finnish type).
Zorgati H, Larsson M, Ren W, ..., Li W, Robinson RC
Proc. Natl. Acad. Sci. U.S.A. 116 (28) 13958-13963 [2019-07-09; online 2019-06-26]
Generally applicable transcriptome-wide analysis of translation using anota2seq.
Oertlin C, Lorent J, Murie C, ..., Topisirovic I, Larsson O
Nucleic Acids Res. 47 (12) e70 [2019-07-09; online 2019-03-31]
Systems-level immunomonitoring using self-sampled capillary blood
Josyula VS, Lakshmikanth T, Mikes J, Chen Y, Brodin P
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GUESSmyLT: Software to guess the RNA-Seq library type of paired and single end read files
Wik E, Olin H, Haughey C, Klasson L, Dainat J
JOSS 4 (39) 1344 [2019-07-07; online 2019-07-07]
Evolution of Protein Domain Architectures.
Forslund SK, Kaduk M, Sonnhammer ELL
Methods in molecular biology (Clifton, N.J.) 1910 (-) 469-504 [2019-07-07; online 2019-07-07]
Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology.
Spracklen CN, Karaderi T, Yaghootkar H, ..., Loos RJF, Mohlke KL
Am. J. Hum. Genet. 105 (1) 15-28 [2019-07-03; online 2019-06-06]
sRNAbench and sRNAtoolbox 2019: intuitive fast small RNA profiling and differential expression.
Aparicio-Puerta E, Lebrón R, Rueda A, ..., Oliver J, Hackenberg M
Nucleic Acids Res. 47 (W1) W530-W535 [2019-07-02; online 2019-05-23]
Depression, GABA and age correlate with the plasma levels of inflammatory markers
Bhandage AK, Cunningham JL, Jin Z, ..., Ekselius L, Birnir B
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Reference Intervals for Fecal Calprotectin in Pregnant Women Using a Particle Enhanced Turbidimetric Assay.
Fall T, Hedman A, Pershagen G, ..., Helmersson-Karlqvist J, Larsson A
Clin. Lab. 65 (7) - [2019-07-01; online 2019-07-17]
Androgen Receptor Burden and Poor Response to Abiraterone or Enzalutamide in TP53 Wild-Type Metastatic Castration-Resistant Prostate Cancer.
De Laere B, Rajan P, Grönberg H, ..., Lindberg J, CORE-ARV-CTC and ProBIO Investigators
JAMA Oncol 5 (7) 1060-1062 [2019-07-01; online 2019-05-03]
Abstract 3843: LSD1 modulation by allosteric ligands
Emond WB, Geitmann M, Jarvius M, ..., Segerman A, Bremberg U
Cancer Res. 79 (13_Supplement) 3843-3843 [2019-07-01; online 2019-07-01]
A Retro-biosynthesis-Based Route to Generate Pinene-Derived Polyesters.
Stamm A, Biundo A, Schmidt B, ..., Bornscheuer UT, Syrén PO
Chembiochem 20 (13) 1664-1671 [2019-07-01; online 2019-05-21]
Vaginal dysbiosis and the risk of human papillomavirus and cervical cancer: systematic review and meta-analysis.
Brusselaers N, Shrestha S, van de Wijgert J, Verstraelen H
Am J Obstet Gynecol 221 (1) 9-18.e8 [2019-07-00; online 2018-12-12]
The autoimmune targets in IPEX are dominated by gut epithelial proteins.
Eriksson D, Bacchetta R, Gunnarsson HI, ..., Kämpe O, Landegren N
J. Allergy Clin. Immunol. 144 (1) 327-330.e8 [2019-07-00; online 2019-04-23]
TANK-binding kinase 1 is a mediator of platelet-induced EMT in mammary carcinoma cells.
Zhang Y, Unnithan RVM, Hamidi A, ..., Cedervall J, Olsson AK
FASEB J. 33 (7) 7822-7832 [2019-07-00; online 2019-03-26]
Structural basis of inhibition of the human serine hydroxymethyltransferase SHMT2 by antifolate drugs.
Scaletti E, Jemth AS, Helleday T, Stenmark P
FEBS Lett. 593 (14) 1863-1873 [2019-07-00; online 2019-06-10]
Stratification of asthma phenotypes by airway proteomic signatures.
Schofield JPR, Burg D, Nicholas B, ..., Djukanović R, U-BIOPRED Study Group
J. Allergy Clin. Immunol. 144 (1) 70-82 [2019-07-00; online 2019-03-28]
Seeking the ultimate challenge.
Brodin P
Nat. Med. 25 (7) 1026 [2019-07-00; online 2019-07-05]
Immune cell constitution in bone marrow microenvironment predicts outcome in adult ALL.
Hohtari H, Brück O, Blom S, ..., Porkka K, Mustjoki S
Leukemia 33 (7) 1570-1582 [2019-07-00; online 2019-01-11]
Hemostatic Genes Exhibit a High Degree of Allele-Specific Regulation in Liver.
Olsson Lindvall M, Hansson L, Klasson S, ..., Jern C, Stanne TM
Thromb. Haemost. 119 (7) 1072-1083 [2019-07-00; online 2019-04-29]
Has2 natural antisense RNA and Hmga2 promote Has2 expression during TGFβ-induced EMT in breast cancer.
Kolliopoulos C, Lin CY, Heldin CH, Moustakas A, Heldin P
Matrix Biol. 80 (-) 29-45 [2019-07-00; online 2018-09-05]
Epigenome-wide association study of lung function level and its change.
Imboden M, Wielscher M, Rezwan FI, ..., Jarvis D, Probst-Hensch NM
Eur. Respir. J. 54 (1) - [2019-07-00; online 2019-07-04]
Drug-Induced Liver Injury due to Flucloxacillin: Relevance of Multiple Human Leukocyte Antigen Alleles.
Nicoletti P, Aithal GP, Chamberlain TC, ..., Daly AK, International Drug-Induced Liver Injury Consortium (iDILIC)
Clin. Pharmacol. Ther. 106 (1) 245-253 [2019-07-00; online 2019-03-19]
Dog10K: an international sequencing effort to advance studies of canine domestication, phenotypes and health.
Ostrander EA, Wang GD, Larson G, ..., Zhang YP, Dog10K Consortium
Natl Sci Rev 6 (4) 810-824 [2019-07-00; online 2019-04-10]
Different time-dependent changes of risk for evolution in chronic lymphocytic leukemia with mutated or unmutated antigen B cell receptors.
Moysiadis T, Baliakas P, Rossi D, ..., Ghia P, Stamatopoulos K
Leukemia 33 (7) 1801-1805 [2019-07-00; online 2019-01-24]
Author Correction: Genome sequencing and population genomic analyses provide insights into the adaptive landscape of silver birch.
Salojärvi J, Smolander OP, Nieminen K, ..., Helariutta Y, Kangasjärvi J
Nat. Genet. 51 (7) 1187-1189 [2019-07-00; online 2019-06-15]
Analyzing DNA methylation patterns in subjects diagnosed with schizophrenia using machine learning methods.
Torabi Moghadam B, Etemadikhah M, Rajkowska G, ..., Feuk L, Carlström EL
J Psychiatr Res 114 (-) 41-47 [2019-07-00; online 2019-04-02]
Silencing of Aberrant Secretory Protein Expression by Disease-Associated Mutations.
Tikhonova EB, Karamysheva ZN, von Heijne G, Karamyshev AL
J. Mol. Biol. 431 (14) 2567-2580 [2019-06-28; online 2019-05-14]
Exploring Molecular Signs of Sex in the Marine Diatom Skeletonema marinoi.
Ferrante MI, Entrambasaguas L, Johansson M, ..., Montresor M, Godhe A
Genes (Basel) 10 (7) - [2019-06-28; online 2019-06-28]
funMotifs: Tissue-specific transcription factor motifs
Umer HM, Smolinska-Garbulowska K, Marzouka Nad, ..., Wadelius C, Komorowski J
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The mitogenome of Norway spruce and a reappraisal of mitochondrial recombination in plants
Sullivan AR, Eldfjell Y, Schiffthaler B, ..., Street NR, Wang XR
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Structural and mutational analysis of the ribosome-arresting human XBP1u.
Shanmuganathan V, Schiller N, Magoulopoulou A, ..., von Heijne G, Beckmann R
Elife 8 (-) - [2019-06-27; online 2019-06-27]
Pharmacogenomics of statin-related myopathy: Meta-analysis of rare variants from whole-exome sequencing.
Floyd JS, Bloch KM, Brody JA, ..., Alfirevic A, PREDICTION-ADR Consortium and EUDRAGENE
PLoS ONE 14 (6) e0218115 [2019-06-26; online 2019-06-26]
A rapid smartphone-based lactate dehydrogenase test for neonatal diagnostics at the point of care.
Halvorsen CP, Olson L, Araújo AC, ..., Winbladh B, Russom A
Sci Rep 9 (1) 9301 [2019-06-26; online 2019-06-26]
A Role for the VPS Retromer in Brucella Intracellular Replication Revealed by Genomewide siRNA Screening.
Casanova A, Low SH, Québatte M, ..., Ben-Tekaya H, Dehio C
mSphere 4 (3) - [2019-06-26; online 2019-06-26]
Deriving Disease Modules from the Compressed Transcriptional Space Embedded in a Deep Auto-encoder
Dwivedi SK, Tjärnberg A, Tegnér J, Gustafsson M
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High-density lipoprotein characteristics and coronary heart disease: a Mendelian randomization study
Prats-Uribe A, Sayols-Baixeras S, Fernández-Sanlés A, ..., Hernáez Á, Elosua R
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Author response: Structural and mutational analysis of the ribosome-arresting human XBP1u
Shanmuganathan V, Schiller N, Magoulopoulou A, ..., von Heijne G, Beckmann R
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Impact of Intracellular Concentrations on Metabolic Drug-Drug Interaction Studies.
Treyer A, Ullah M, Parrott N, ..., Fowler S, Artursson P
AAPS J 21 (5) 77 [2019-06-18; online 2019-06-18]
Immune cells lacking Y chromosome have widespread dysregulation of autosomal genes
Dumanski JP, Halvardson J, Davies H, ..., Ryś J, Forsberg LA
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A Call for Blood-In Human Immunology.
Brodin P, Duffy D, Quintana-Murci L
Immunity 50 (6) 1335-1336 [2019-06-18; online 2019-06-20]
PconsFam: An Interactive Database of Structure Predictions of Pfam Families.
Lamb J, Jarmolinska AI, Michel M, ..., Sulkowska JI, Elofsson A
J. Mol. Biol. 431 (13) 2442-2448 [2019-06-14; online 2019-02-21]
A simple pressure-assisted method for MicroED specimen preparation
Zhao J, Xu H, Lebrette H, ..., Högbom M, Zou X
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SweHLA: the high confidence HLA typing bio-resource drawn from 1 000 Swedish genomes
Nordin J, Ameur A, Lindblad-Toh K, Gyllensten U, Meadows JRS
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Mitigating Anticipated Effects of Systematic Errors Supports Sister-Group Relationship between Xenacoelomorpha and Ambulacraria.
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The Nordic Zebrafish and Husbandry Meeting 2018.
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Redox Biol 24 (-) 101227 [2019-06-00; online 2019-05-21]
PF230 THE RNA HELICASE DDX17 PROTECTS ACUTE MYELOID LEUKEMIA CELLS AGAINST DNA DAMAGE
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Hemasphere 3 (S1) 67 [2019-06-00; online 2019-06-30]
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Maternal exposure to arsenic and mercury in small-scale gold mining areas of Northern Tanzania.
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High-Dimensional Multi-Block Analysis of Factors Associated with Thrombin Generation Potential
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Epithelial dysregulation in obese severe asthmatics with gastro-oesophageal reflux.
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Droplet Dilution Unit Operation Including Bead Washing Using Integrated Acoustophoresis
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A novel RAD21 p.(Gln592del) variant expands the clinical description of Cornelia de Lange syndrome type 4 - Review of the literature.
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A Brief History of Protein Sorting Prediction.
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Sex differences in IL-17 contribute to chronicity in male versus female urinary tract infection.
Zychlinsky Scharff A, Rousseau M, Lacerda Mariano L, ..., Duffy D, Ingersoll MA
JCI Insight 5 (13) - [2019-05-30; online 2019-05-30]
Camila Consiglio DDLS Fellow
Plasma protein profiling reveals candidate biomarkers for multiple sclerosis treatment.
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PLoS ONE 14 (5) e0217208 [2019-05-29; online 2019-05-29]
Membrane integration and topology of RIFIN and STEVOR proteins of the Plasmodium falciparum parasite
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Type I interferons in host defence and inflammatory diseases.
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Lupus Sci Med 6 (1) e000336 [2019-05-28; online 2019-05-28]
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Ice-Age Climate Adaptations Trap the Alpine Marmot in a State of Low Genetic Diversity.
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Curr. Biol. 29 (10) 1712-1720.e7 [2019-05-20; online 2019-05-09]
Aleksej Zelezniak SciLifeLab Fellow
Detecting Novel Sequence Signals in Targeting Peptides Using Deep Learning
Almagro Armenteros JJ, Salvatore M, Emanuelsson O, ..., Elofsson A, Nielsen H
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Circulating Levels of Interferon Regulatory Factor-5 Associates With Subgroups of Systemic Lupus Erythematosus Patients.
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Front Immunol 10 (-) 1029 [2019-05-17; online 2019-05-17]
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In vitro phosphodiesterase 10A (PDE10A) binding in whole hemisphere human brain using the PET radioligand [18F]MNI-659.
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Cell generation dynamics underlying naïve T cell homeostasis in adult humans
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Automated Cell Processing for Mass Cytometry Experiments.
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Intra-individual changes in the frequency of mosaic loss of chromosome Y over time estimated with a new method
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Genome Sequence of Kordia sp. Strain SMS9 Identified in a Non-Axenic Culture of the Diatom Skeletonema marinoi.
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Periodontal Health and Oral Microbiota in Patients with Rheumatoid Arthritis.
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Antibody Validation Strategy for Nuclear Receptors.
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Prompt apoptotic response to high glucose in SGLT-expressing renal cells.
Nilsson LM, Zhang L, Bondar A, ..., Scott L, Aperia A
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Endocr Connect 8 (5) 559-570 [2019-05-01; online 2019-04-10]
Pervasive hybridizations in the history of wheat relatives.
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Sci Adv 5 (5) eaav9188 [2019-05-00; online 2019-05-01]
PRR14L mutations are associated with chromosome 22 acquired uniparental disomy, age-related clonal hematopoiesis and myeloid neoplasia.
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Leukemia 33 (5) 1184-1194 [2019-05-00; online 2018-12-20]
No evidence of a causal association of type 2 diabetes and glucose metabolism with atrial fibrillation.
Harati H, Zanetti D, Rao A, ..., Ingelsson E, Knowles JW
Diabetologia 62 (5) 800-804 [2019-05-00; online 2019-02-27]
Interferon signature in patients with STAT1 gain-of-function mutation is epigenetically determined.
Kaleviste E, Saare M, Leahy TR, ..., Peterson P, Kisand K
Eur. J. Immunol. 49 (5) 790-800 [2019-05-00; online 2019-03-07]
Identification of 22 novel loci associated with urinary biomarkers of albumin, sodium, and potassium excretion.
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Kidney Int. 95 (5) 1197-1208 [2019-05-00; online 2019-03-12]
A Missense Variant in PTPN22 is a Risk Factor for Drug-induced Liver Injury.
Cirulli ET, Nicoletti P, Abramson K, ..., Drug-Induced Liver Injury Network (DILIN) investigators , International DILI consortium (iDILIC)
Gastroenterology 156 (6) 1707-1716.e2 [2019-05-00; online 2019-01-18]
Invasive cervical tumors with high and low HPV titer represent molecular subgroups with different disease etiology.
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Integrin α10, a Novel Therapeutic Target in Glioblastoma, Regulates Cell Migration, Proliferation, and Survival.
Munksgaard Thorén M, Chmielarska Masoumi K, Krona C, ..., Holmqvist B, Lundgren-Åkerlund E
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Atmospheric Deposition Impact on Bacterial Community Composition in the NW Mediterranean.
Marín-Beltrán I, Logue JB, Andersson AF, Peters F
Front Microbiol 10 (-) 858 [2019-04-24; online 2019-04-24]
Body composition and atrial fibrillation: a Mendelian randomization study.
Tikkanen E, Gustafsson S, Knowles JW, ..., Burgess S, Ingelsson E
Eur. Heart J. 40 (16) 1277-1282 [2019-04-21; online 2019-02-06]
The horse Y chromosome as an informative marker for tracing sire lines.
Felkel S, Vogl C, Rigler D, ..., Brem G, Wallner B
Sci Rep 9 (1) 6095 [2019-04-15; online 2019-04-15]
The Genome of Blue-Capped Cordon-Bleu Uncovers Hidden Diversity of LTR Retrotransposons in Zebra Finch.
Boman J, Frankl-Vilches C, da Silva Dos Santos M, ..., Gahr M, Suh A
Genes (Basel) 10 (4) - [2019-04-13; online 2019-04-13]
Impact of severe OSA during REM sleep on cardiac and inflammatory protein levels
Ljunggren M, Theorell-Haglöw J, Freyhult E, ..., Janson C, Lindberg E
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Receptor-Independent Transfer of Low Density Lipoprotein Cargo to Biomembranes.
Axmann M, Sezgin E, Karner A, ..., Stangl H, Plochberger B
Nano Lett. 19 (4) 2562-2567 [2019-04-10; online 2019-03-08]
Erdinc Sezgin SciLifeLab Fellow
Breast cancer quantitative proteome and proteogenomic landscape.
Johansson HJ, Socciarelli F, Vacanti NM, ..., Børresen-Dale AL, Lehtiö J
Nat Commun 10 (1) 1600 [2019-04-08; online 2019-04-08]
A hybrid de novo genome assembly of the honeybee, Apis mellifera, with chromosome-length scaffolds.
Wallberg A, Bunikis I, Pettersson OV, ..., Robinson GE, Webster MT
BMC Genomics 20 (1) 275 [2019-04-08; online 2019-04-08]
High-Quality Library Preparation for NGS-Based Immunoglobulin Germline Gene Inference and Repertoire Expression Analysis.
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Front Immunol 10 (-) 660 [2019-04-05; online 2019-04-05]
System-wide Profiling of RNA-Binding Proteins Uncovers Key Regulators of Virus Infection.
Garcia-Moreno M, Noerenberg M, Ni S, ..., Mohammed S, Castello A
Mol. Cell 74 (1) 196-211.e11 [2019-04-04; online 2019-02-21]
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Regulation of adenylyl cyclase 5 in striatal neurons confers the ability to detect coincident neuromodulatory signals
Bruce NJ, Narzi D, Trpevski D, ..., Carloni P, Kotaleski JH
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A validated strategy to infer protein biomarkers from RNA-Seq by combining multiple mRNA splice variants and time-delay
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Detection of bacterial pathogens and drug resistance markers using Rolling circle amplification v1
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Case Reports of Pre-clinical Replication Studies in Metabolism and Diabetes.
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Cell Metab. 29 (4) 795-802 [2019-04-02; online 2019-03-14]
Gustaf Christoffersson SciLifeLab Fellow
B cell profiling in malaria reveals expansion and remodelling of CD11c+ B cell subsets.
Sundling C, Rönnberg C, Yman V, ..., Persson KE, Färnert A
JCI Insight 5 (9) - [2019-04-02; online 2019-04-02]
The biology of the cell - insights from mass cytometry.
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SignalP 5.0 improves signal peptide predictions using deep neural networks.
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Placing RNA in context and space - methods for spatially resolved transcriptomics.
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FEBS J. 286 (8) 1468-1481 [2019-04-00; online 2018-03-31]
Measuring nanoscale diffusion dynamics in cellular membranes with super-resolution STED-FCS.
Sezgin E, Schneider F, Galiani S, ..., Lagerholm BC, Eggeling C
Nat Protoc 14 (4) 1054-1083 [2019-04-00; online 2019-03-06]
Erdinc Sezgin SciLifeLab Fellow
In vivo efficiency of antimicrobial inorganic bone grafts in osteomyelitis treatments.
Mestres G, Fernandez-Yague MA, Pastorino D, ..., Manzanares-Céspedes MC, Ginebra MP
Mater Sci Eng C Mater Biol Appl 97 (-) 84-95 [2019-04-00; online 2018-11-28]
Identification of Candidate Plasma Protein Biomarkers for Cervical Cancer Using the Multiplex Proximity Extension Assay.
Berggrund M, Enroth S, Lundberg M, ..., Olovsson M, Gyllensten U
Mol. Cell Proteomics 18 (4) 735-743 [2019-04-00; online 2019-01-28]
Genetics of adaptation in modern chicken.
Qanbari S, Rubin CJ, Maqbool K, ..., Simianer H, Andersson L
PLoS Genet 15 (4) e1007989 [2019-04-00; online 2019-04-29]
Dual roles of heparanase in human carotid plaque calcification.
Aldi S, Eriksson L, Kronqvist M, ..., Österholm C, Hedin U
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Absence of TXNIP in Humans Leads to Lactic Acidosis and Low Serum Methionine Linked to Deficient Respiration on Pyruvate.
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Diabetes 68 (4) 709-723 [2019-04-00; online 2019-02-12]
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Reid S, Alexsson A, Frodlund M, ..., Ronnblom L, Leonard D
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Structural and mutational analysis of the ribosome-arresting human XBP1u
Shanmuganathan V, Schiller N, Magoulopoulou A, ..., von Heijne G, Beckmann R
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STATegra: a comprehensive multi-omics dataset of B-cell differentiation in mouse
Gomez-Cabrero D, Tarazona S, Ferreirós-Vidal I, ..., Tegner J, Conesa A
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Transmission dynamics study of tuberculosis isolates with whole genome sequencing in southern Sweden.
Alaridah N, Hallbäck ET, Tångrot J, ..., Kaijser B, Godaly G
Sci Rep 9 (1) 4931 [2019-03-20; online 2019-03-20]
Addendum: The FAIR Guiding Principles for scientific data management and stewardship.
Wilkinson MD, Dumontier M, Jan Aalbersberg I, ..., Zhao J, Mons B
Sci Data 6 (1) 6 [2019-03-19; online 2019-03-19]
A deep learning framework for nucleus segmentation using image style transfer
Hollandi R, Szkalisity A, Toth T, ..., Smith K, Horvath P
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Pax6 and KDM5C co-occupy a subset of developmentally critical genes including Notch signaling regulators in neural progenitors
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Marine sediments illuminate Chlamydiae diversity and evolution
Dharamshi JE, Tamarit D, Eme L, ..., Spang A, Ettema TJG
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Lithium treatment reverses irradiation-induced changes in rodent neural progenitors
Giulia Z, Shinobu G, Giulia G, ..., Ola H, Klas B
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Transforming growth factor β (TGFβ) induces NUAK kinase expression to fine-tune its signaling output.
Kolliopoulos C, Raja E, Razmara M, ..., Moustakas A, van der Heide LP
J Biol Chem 294 (11) 4119-4136 [2019-03-15; online 2019-01-08]
ST viewer: a tool for analysis and visualization of spatial transcriptomics datasets.
Fernández Navarro J, Lundeberg J, Ståhl PL
Bioinformatics 35 (6) 1058-1060 [2019-03-15; online 2019-03-16]
Live detection of neural stem and glioblastoma cells by an oligothiophene derivative
Ilkhanizadeh S, Gracias A, Åslund AKO, ..., Hermanson O, Nilsson KPR
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Automatic rat brain segmentation from MRI using statistical shape models and random forest
Bendazzoli S, Brusini I, Damberg P, ..., Andersson L, Wang C
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A generalized framework for controlling FDR in gene regulatory network inference.
Morgan D, Tjärnberg A, Nordling TEM, Sonnhammer ELL
Bioinformatics 35 (6) 1026-1032 [2019-03-15; online 2018-09-01]
Cytogenetic complexity in chronic lymphocytic leukemia: definitions, associations, and clinical impact.
Baliakas P, Jeromin S, Iskas M, ..., Stamatopoulos K, ERIC, the European Research Initiative on CLL
Blood 133 (11) 1205-1216 [2019-03-14; online 2019-01-02]
Loss of ErbB3 redirects Integrin β1 from early endosomal recycling to secretion in extracellular vesicles
Rodrigues-Junior DM, Sáez-Ibáñez AR, Terabayashi T, ..., Moustakas A, Ferby I
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MTH1 promotes mitotic progression to avoid oxidative DNA damage in cancer cells
Gad H, Mortusewicz O, Rudd SG, ..., Berglund UW, Helleday T
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Secondary ossification center induces and protects growth plate structure
Xie M, Gol’din P, Herdina AN, ..., Eriksson A, Chagin AS
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Genomic analysis reveals shared genes and pathways in human and canine angiosarcoma
Megquier K, Turner-Maier J, Swofford R, ..., Elvers I, Lindblad-Toh K
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Dog ownership and cardiovascular risk factors: a nationwide prospective register-based cohort study.
Mubanga M, Byberg L, Egenvall A, ..., Ingelsson E, Fall T
BMJ Open 9 (3) e023447 [2019-03-07; online 2019-03-07]
Gramicidin Increases Lipid Flip-Flop in Symmetric and Asymmetric Lipid Vesicles.
Doktorova M, Heberle FA, Marquardt D, ..., Weinstein H, Andersen OS
Biophys. J. 116 (5) 860-873 [2019-03-05; online 2019-01-25]
DDLS Fellow Milka Doktorova
A microfluidic platform towards automated multiplexed in situ sequencing.
Maïno N, Hauling T, Cappi G, ..., Dupouy DG, Nilsson M
Sci Rep 9 (1) 3542 [2019-03-05; online 2019-03-05]
A Systematic Investigation of the Malignant Functions and Diagnostic Potential of the Cancer Secretome.
Robinson JL, Feizi A, Uhlén M, Nielsen J
Cell Reports 26 (10) 2622-2635.e5 [2019-03-05; online 2019-03-07]
Taxonomic status of the Australian dingo: the case for Canis dingo Meyer, 1793.
Smith BP, Cairns KM, Adams JW, ..., Morrant DS, Crowther MS
Zootaxa 4564 (1) zootaxa.4564.1.6 [2019-03-04; online 2019-03-04]
The high efficacy of muscarinic M4 receptor in D1 medium spiny neurons reverses striatal hyperdopaminergia.
Nair AG, Castro LRV, El Khoury M, ..., Hellgren-Kotaleski J, Vincent P
Neuropharmacology 146 (-) 74-83 [2019-03-01; online 2018-11-22]
Small molecule activators of the p53 response.
Ladds MJGW, Laín S
J Mol Cell Biol 11 (3) 245-254 [2019-03-01; online 2019-01-29]
Container-based bioinformatics with Pachyderm.
Novella JA, Emami Khoonsari P, Herman S, ..., Kultima K, Spjuth O
Bioinformatics 35 (5) 839-846 [2019-03-01; online 2018-08-14]
Summer comes to the Southern Ocean: how phytoplankton shape bacterioplankton communities far into the deep dark sea
Richert I, Yager PL, Dinasquet J, ..., Bertilsson S, Scofield DG
Ecosphere 10 (3) - [2019-03-00; online 2019-03-12]
Spontaneous calcium activity in metanephric mesenchymal cells regulates branching morphogenesis in the embryonic kidney.
Fontana JM, Khodus GR, Unnersjö-Jess D, ..., Aperia A, Brismar H
FASEB J. 33 (3) 4089-4096 [2019-03-00; online 2018-11-29]
Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.
Justice AE, Karaderi T, Highland HM, ..., T2D-Genes Consortium , MAGIC Investigators
Nat. Genet. 51 (3) 452-469 [2019-03-00; online 2019-02-18]
Plant microRNAs in human sera are likely contaminants.
Fromm B, Kang W, Rovira C, ..., Friedländer MR, Tosar JP
J Nutr Biochem 65 (-) 139-140 [2019-03-00; online 2018-09-05]
Marc Friedländer SciLifeLab Fellow
Molecular mechanisms underlying striatal synaptic plasticity: relevance to chronic alcohol consumption and seeking.
Blackwell KT, Salinas AG, Tewatia P, ..., Hellgren Kotaleski J, Lovinger DM
Eur. J. Neurosci. 49 (6) 768-783 [2019-03-00; online 2018-04-20]
Identification of metabolic profiles associated with human exposure to perfluoroalkyl substances.
Salihovic S, Fall T, Ganna A, ..., Ingelsson E, Lind L
J Expo Sci Environ Epidemiol 29 (2) 196-205 [2019-03-00; online 2018-09-05]
High-Resolution Regulatory Maps Connect Vascular Risk Variants to Disease-Related Pathways.
Åkerborg Ö, Spalinskas R, Pradhananga S, ..., Eriksson PP, Sahlén P
Circ Genom Precis Med 12 (3) e002353 [2019-03-00; online 2019-02-21]
Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations.
Sakornsakolpat P, Prokopenko D, Lamontagne M, ..., SpiroMeta Consortium , International COPD Genetics Consortium
Nat. Genet. 51 (3) 494-505 [2019-03-00; online 2019-02-25]
Chromosomal inversions associated with environmental adaptation in honeybees.
Christmas MJ, Wallberg A, Bunikis I, ..., Wallerman O, Webster MT
Mol. Ecol. 28 (6) 1358-1374 [2019-03-00; online 2018-12-21]
Best Practices Recommendations for Diagnostic Immunohistochemistry in Lung Cancer.
Yatabe Y, Dacic S, Borczuk AC, ..., Wistuba I, Moreira AL
J Thorac Oncol 14 (3) 377-407 [2019-03-00; online 2018-12-18]
Allergen-specific IgE over time in women before, during and after pregnancy.
Hedman AM, Lundholm C, Scheynius A, ..., Pershagen G, Almqvist C
Allergy 74 (3) 625-628 [2019-03-00; online 2018-12-09]
A simple approach for restoration of differentiation and function in cryopreserved human hepatocytes.
Ölander M, Wiśniewski JR, Flörkemeier I, ..., Urdzik J, Artursson P
Arch. Toxicol. 93 (3) 819-829 [2019-03-00; online 2018-12-17]
A radical switch in clonality reveals a stem cell niche in the epiphyseal growth plate.
Newton PT, Li L, Zhou B, ..., Sävendahl L, Chagin AS
Nature 567 (7747) 234-238 [2019-03-00; online 2019-02-27]
A Phenotypic Screening Assay Identifies Modulators of Diamond Blackfan Anemia.
Siva K, Ek F, Chen J, ..., Lundbäck T, Flygare J
SLAS Discov 24 (3) 304-313 [2019-03-00; online 2019-02-21]
High-density spatial transcriptomics arrays for in situ tissue profiling
Vickovic S, Eraslan G, Klughammer J, ..., Regev A, Ståhl PL
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Sanja Vickovic SciLifeLab Fellow
A novel mutation tolerant padlock probe design for multiplexed detection of hypervariable RNA viruses.
Ciftci S, Neumann F, Hernández-Neuta I, ..., Madaboosi N, Nilsson M
Sci Rep 9 (1) 2872 [2019-02-27; online 2019-02-27]
Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells
Samudyata , Amaral PP, Engström PG, ..., Kouzarides T, Castelo-Branco G
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Biocatalysis for terpene-based polymers.
Farhat W, Stamm A, Robert-Monpate M, Biundo A, Syrén PO
Z Naturforsch C J Biosci 74 (3-4) 91-100 [2019-02-25; online 2019-02-23]
Tissue lysis and digestion for MS analysis v1
Kotol D
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Prediction of response to anti-cancer drugs becomes robust via network integration of molecular data.
Franco M, Jeggari A, Peuget S, ..., Selivanova G, Alexeyenko A
Sci Rep 9 (1) 2379 [2019-02-20; online 2019-02-20]
High Spatial Resolution Profiling in Tree Species
Giacomello S, Delhomme N, Niittylä T, Tuominen H, Street NR
- - (-) 329-360 [2019-02-20; online 2019-02-20]
Gene regulatory network of human GM-CSF secreting T helper cells
Éliás S, Schmidt A, Gomez-Cabrero D, Tegnér J
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DRAFT - Robotic automation of production and the recovery of cell spheroids
Langer K, Jönsson H
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HPA Cell Atlas Standard Immunostaining Protocol v1
Thul P, Axelsson U
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Individualization of Hematopoietic Stem Cell Transplantation Using Alpha/Beta T-Cell Depletion.
Rådestad E, Sundin M, Törlén J, ..., Mattsson J, Uhlin M
Front Immunol 10 (-) 189 [2019-02-11; online 2019-02-11]
HybISS: Hybridization-based In Situ Sequencing v1
Gyllborg D, Nilsson M
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Modeling double strand break susceptibility to interrogate structural variation in cancer.
Ballinger TJ, Bouwman BAM, Mirzazadeh R, ..., Crosetto N, Semple CA
Genome Biol. 20 (1) 28 [2019-02-08; online 2019-02-08]
Synthesis of Sulfonimidamide‐Based Amino Acid Building Blocks with Orthogonal Protecting Groups
Chinthakindi PK, Benediktsdottir A, Ibrahim A, ..., Chen Y, Sandström A
Eur. J. Org. Chem. 2019 (5) 1045-1057 [2019-02-07; online 2019-01-02]
Virus-Based Immunotherapy of Glioblastoma.
Martikainen M, Essand M
Cancers (Basel) 11 (2) - [2019-02-05; online 2019-02-05]
A systems-based map of human brain cell-type enriched genes and malignancy-associated endothelial changes
Dusart P, Hallström BM, Renne T, ..., Uhlén M, Butler LM
- - (-) - [2019-02-05; online 2019-02-05]
SynQuant: An Automatic Tool to Quantify Synapses from Microscopy Images
Wang Y, Wang C, Ranefall P, ..., Tian L, Yu G
- - (-) - [2019-02-02; online 2019-02-02]
Structural Patching Fosters Divergence of Mitochondrial Ribosomes.
Petrov AS, Wood EC, Bernier CR, ..., Brown A, Amunts A
Mol. Biol. Evol. 36 (2) 207-219 [2019-02-01; online 2018-12-06]
Alexey Amunts SciLifeLab Fellow
Protein measurements in venous plasma, earlobe capillary plasma and in plasma stored on filter paper.
Siart B, de Oliveira FMS, Shen Q, ..., Kamali-Moghaddam M, Wallner B
Anal. Biochem. 566 (-) 146-150 [2019-02-01; online 2018-11-22]
Abstract A128: Tumor endothelial cells say IDO to CD40-stimulating immunotherapy
Dimberg A, Karampatzakis A, Tuit S, ..., Essand M, Georganaki M
Cancer Immunol Res 7 (2_Supplement) A128-A128 [2019-02-01; online 2019-02-01]
AFISsys - An autonomous instrument for the preservation of brackish water samples for microbial metatranscriptome analysis.
Charvet S, Riemann L, Alneberg J, ..., Fischer U, Labrenz M
Water Res 149 (-) 351-361 [2019-02-01; online 2018-11-12]
miR-31 regulates energy metabolism and is suppressed in T cells from patients with Sjögren's syndrome.
Johansson A, Nyberg WA, Sjöstrand M, ..., Jagodic M, Espinosa A
Eur. J. Immunol. 49 (2) 313-322 [2019-02-00; online 2018-10-22]
Upregulated BMP-Smad signaling activity in the glucuronyl C5-epimerase knock out MEF cells.
Batool T, Fang J, Jansson V, ..., Moustakas A, Li JP
Cell. Signal. 54 (-) 122-129 [2019-02-00; online 2018-11-17]
The genomic basis of adaptation to high-altitude habitats in the eastern honey bee (Apis cerana).
Montero-Mendieta S, Tan K, Christmas MJ, ..., Wallberg A, Webster MT
Mol. Ecol. 28 (4) 746-760 [2019-02-00; online 2019-02-04]
Tailored approaches grounded on immunogenetic features for refined prognostication in chronic lymphocytic leukemia.
Baliakas P, Moysiadis T, Hadzidimitriou A, ..., Stamatopoulos K, European Research Initiative on CLL (ERIC)
Haematologica 104 (2) 360-369 [2019-02-00; online 2018-09-27]
T-cell inflamed tumor microenvironment predicts favorable prognosis in primary testicular lymphoma.
Leivonen SK, Pollari M, Brück O, ..., Mustjoki S, Leppä S
Haematologica 104 (2) 338-346 [2019-02-00; online 2018-09-20]
Phosphatidylinositol Inhibits TRPV1 via its Vanilloid Binding Site
Torun Yazici A, Gianti E, Kasimova MA, Carnevale V, Rohacs T
Biophysical Journal 116 (3) 536a [2019-02-00; online 2019-02-00]
Pandemrix-induced narcolepsy is associated with genes related to immunity and neuronal survival.
Hallberg P, Smedje H, Eriksson N, ..., Wadelius M, Swedegene
EBioMedicine 40 (-) 595-604 [2019-02-00; online 2019-01-30]
PD-L1 as a prognostic factor in gastric cancer patients
Polom K, Shen Q, Williams C, ..., Kamali-Moghaddam M, Roviello F
European Journal of Surgical Oncology 45 (2) e138-e139 [2019-02-00; online 2019-02-00]
Molecular Imaging of a New Multimodal Microbubble for Adhesion Molecule Targeting.
Ahmed M, Gustafsson B, Aldi S, ..., Hedin U, Caidahl K
Cell Mol Bioeng 12 (1) 15-32 [2019-02-00; online 2018-11-28]
Individual and stable autoantibody repertoires in healthy individuals.
Neiman M, Hellström C, Just D, ..., Uhlén M, Nilsson P
Autoimmunity 52 (1) 1-11 [2019-02-00; online 2019-03-05]
Common Genetic Variation in Relation to Brachial Vascular Dimensions and Flow-Mediated Vasodilation.
Dörr M, Hamburg NM, Müller C, ..., Benjamin EJ, Schnabel RB
Circ Genom Precis Med 12 (2) e002409 [2019-02-00; online 2019-02-20]
Circulating proteins as predictors of cardiovascular mortality in end-stage renal disease.
Feldreich T, Nowak C, Fall T, ..., Green D, Ärnlöv J
J Nephrol 32 (1) 111-119 [2019-02-00; online 2018-11-29]
Candidate biomarkers for the diagnosis and prognosis of drug-induced liver injury: An international collaborative effort.
Church RJ, Kullak-Ublick GA, Aubrecht J, ..., Poynard T, Watkins PB
Hepatology 69 (2) 760-773 [2019-02-00; online 2018-06-27]
BCG-induced cytokine release in bladder cancer cells is regulated by Ca2+ signaling.
Ibarra C, Karlsson M, Codeluppi S, ..., Miyakawa A, Uhlén P
Mol Oncol 13 (2) 202-211 [2019-02-00; online 2018-12-13]
B cell alterations during BAFF inhibition with belimumab in SLE.
Ramsköld D, Parodis I, Lakshmikanth T, ..., Gunnarsson I, Malmström V
EBioMedicine 40 (-) 517-527 [2019-02-00; online 2018-12-26]
Allosteric Modulation via Transmembrane Interfaces in a Pentameric Ligand-Gated Ion Channel
Howard RJ, Zhuang Y, Nakamura S, ..., Orellana L, Lindahl E
Biophysical Journal 116 (3) 245a-246a [2019-02-00; online 2019-02-00]
Adenoviral detection by recombinase polymerase amplification and vertical flow paper microarray.
Nybond S, Réu P, Rhedin S, ..., Gantelius J, Svahn HA
Anal Bioanal Chem 411 (4) 813-822 [2019-02-00; online 2018-11-29]
Adenosine Kinase Deficiency: Report and Review.
Alhusani A, Obaid A, Blom HJ, Wedell A, Alfadhel M
Neuropediatrics 50 (1) 46-50 [2019-02-00; online 2018-11-26]
Centromere-mediated chromosome break drives karyotype evolution in closely related Malassezia species
Sankaranarayanan SR, Ianiri G, Reza MH, ..., Heitman J, Sanyal K
- - (-) - [2019-01-29; online 2019-01-29]
ADAMDEC1 maintains a novel growth factor signaling loop in cancer stem cells
Hale JS, Jimenez-Pascual A, Kordowski A, ..., Lathia JD, Siebzehnrubl FA
- - (-) - [2019-01-26; online 2019-01-26]
A Structural Basis for 129 Xe Hyper-CEST Signal in TEM-1 β-Lactamase.
Roose BW, Zemerov SD, Wang Y, ..., Carnevale V, Dmochowski IJ
Chemphyschem 20 (2) 260-267 [2019-01-21; online 2018-09-13]
Killer whale genomes reveal a complex history of recurrent admixture and vicariance
Foote AD, Martin MD, Louis M, ..., Wolf JBW, Morin PA
- - (-) - [2019-01-16; online 2019-01-16]
A micro-dispenser for long-term storage and controlled release of liquids.
Kazemzadeh A, Eriksson A, Madou M, Russom A
Nat Commun 10 (1) 189 [2019-01-14; online 2019-01-14]
Targeted Analysis of Serum Proteins Encoded at Known Inflammatory Bowel Disease Risk Loci.
Drobin K, Assadi G, Hong MG, ..., D'Amato M, Halfvarson J
Inflamm Bowel Dis 25 (2) 306-316 [2019-01-10; online 2018-10-26]
The Pfam protein families database in 2019.
El-Gebali S, Mistry J, Bateman A, ..., Tosatto SCE, Finn RD
Nucleic Acids Res. 47 (D1) D427-D432 [2019-01-08; online 2018-10-26]
GROmaρs: A GROMACS-Based Toolset to Analyze Density Maps Derived from Molecular Dynamics Simulations.
Briones R, Blau C, Kutzner C, de Groot BL, Aponte-Santamaría C
Biophys. J. 116 (1) 4-11 [2019-01-08; online 2018-12-01]
Ascetosporea.
Bass D, Ward GM, Burki F
Curr. Biol. 29 (1) R7-R8 [2019-01-07; online 2019-01-09]
Fabien Burki SciLifeLab Fellow
The Versatility of SMRT Sequencing.
Hestand MS, Ameur A
Genes (Basel) 10 (1) - [2019-01-04; online 2019-01-04]
The BAF and PRC2 Complex Subunits Dpf2 and Eed Antagonistically Converge on Tbx3 to Control ESC Differentiation.
Zhang W, Chronis C, Chen X, ..., Sahlén P, Plath K
Cell Stem Cell 24 (1) 138-152.e8 [2019-01-03; online 2019-01-05]
SubCellBarCode: Proteome-wide Mapping of Protein Localization and Relocalization.
Orre LM, Vesterlund M, Pan Y, ..., Fredlund E, Lehtiö J
Mol. Cell 73 (1) 166-182.e7 [2019-01-03; online 2019-01-05]
Spatial and temporal localization of immune transcripts defines hallmarks and diversity in the tuberculosis granuloma
Carow B, Hauling T, Qian X, ..., Nilsson M, Rottenberg ME
- - (-) - [2019-01-02; online 2019-01-02]
Saccharomyces cerevisiae respiratory supercomplex III2IV
Rathore S, Berndtsson J, Conrad J, Ott M
- - (-) - [2019-01-02; online 2018-05-15]
Intrinsic blinking characteristics of single colloidal CdSe-CdS/ZnS core-multishell quantum dots
Fu Y, Jussi J, Elmlund L, ..., Wang Q, Brismar H
Phys. Rev. B 99 (3) - [2019-01-02; online 2019-01-02]
A Neural Circuit Mechanism for Encoding Aversive Stimuli in the Mesolimbic Dopamine System.
de Jong JW, Afjei SA, Pollak Dorocic I, ..., Deisseroth K, Lammel S
Neuron 101 (1) 133-151.e7 [2019-01-02; online 2018-11-29]
Iskra Pollak Dorocic SciLifeLab Fellow
Genomic diversity, lifestyles and evolutionary origins of DPANN archaea.
Dombrowski N, Lee JH, Williams TA, Offre P, Spang A
FEMS Microbiol. Lett. 366 (2) - [2019-01-01; online 2019-01-11]
Allele Phasing Greatly Improves the Phylogenetic Utility of Ultraconserved Elements.
Andermann T, Fernandes AM, Olsson U, ..., Faircloth BC, Antonelli A
Syst. Biol. 68 (1) 32-46 [2019-01-01; online 2018-05-18]
DDLS Fellow Tobias Andermann
ZBED6 negatively regulates insulin production, neuronal differentiation, and cell aggregation in MIN6 cells.
Wang X, Jiang L, Wallerman O, ..., Welsh N, Andersson L
FASEB J. 33 (1) 88-100 [2019-01-00; online 2018-06-29]
The DNA Damaging Revolution: PARP Inhibitors and Beyond.
Yap TA, Plummer R, Azad NS, Helleday T
Am Soc Clin Oncol Educ Book 39 (-) 185-195 [2019-01-00; online 2019-05-17]
Temporal and long-term gut microbiota variation in allergic disease: A prospective study from infancy to school age.
Simonyté Sjödin K, Hammarström ML, Rydén P, ..., Engstrand L, West CE
Allergy 74 (1) 176-185 [2019-01-00; online 2018-10-18]
Single-Molecule Sequencing: Towards Clinical Applications.
Ameur A, Kloosterman WP, Hestand MS
Trends Biotechnol 37 (1) 72-85 [2019-01-00; online 2018-08-13]
Roles for globus pallidus externa revealed in a computational model of action selection in the basal ganglia.
Suryanarayana SM, Hellgren Kotaleski J, Grillner S, Gurney KN
Neural Netw 109 (-) 113-136 [2019-01-00; online 2018-10-19]
Regio- and Stereoselective Synthesis of Spirooxindoles via Mizoroki–Heck Coupling of Aryl Iodides
Larhed M, Adeyemi A, Wetzel A, Bergman J, Brånalt J
Synlett 30 (01) 82-88 [2019-01-00; online 2018-12-04]
Proteomic profiling of endothelium-dependent vasodilation.
Lind L, Sundström J, Ärnlöv J, Ingelsson E
J. Hypertens. 37 (1) 216-222 [2019-01-00; online 2018-10-20]
Phylogenomics supports the monophyly of the Cercozoa.
Irwin NAT, Tikhonenkov DV, Hehenberger E, ..., Burki F, Keeling PJ
Mol. Phylogenet. Evol. 130 (-) 416-423 [2019-01-00; online 2018-10-11]
Fabien Burki SciLifeLab Fellow
Mosaic loss of chromosome Y in leukocytes matters.
Forsberg LA, Halvardson J, Rychlicka-Buniowska E, ..., Ingelsson M, Dumanski JP
Nat. Genet. 51 (1) 4-7 [2019-01-00; online 2018-10-31]
Flood pulse regulation of bacterioplankton community composition in an Amazonian floodplain lake
de Melo ML, Bertilsson S, Amaral JHF, ..., Forsberg BR, Sarmento H
Freshw Biol 64 (1) 108-120 [2019-01-00; online 2018-11-05]
Extraction and quantification of phycobiliproteins from the red alga Furcellaria lumbricalis
Saluri M, Kaldmäe M, Tuvikene R
Algal Research 37 (-) 115-123 [2019-01-00; online 2019-01-00]
Combined epithelial marker analysis of tumour budding in stage II colorectal cancer.
Slik K, Blom S, Turkki R, ..., Sundström J, Pellinen T
J Pathol Clin Res 5 (1) 63-78 [2019-01-00; online 2018-11-29]
Affibody‑mediated imaging of EGFR expression in prostate cancer using radiocobalt‑labeled DOTA‑ZEGFR:2377.
Mitran B, Andersson KG, Lindström E, ..., Orlova A, Löfblom J
Oncol Rep 41 (1) 534-542 [2019-01-00; online 2018-10-15]
A quantitative framework for characterizing the evolutionary history of mammalian gene expression.
Chen J, Swofford R, Johnson J, ..., Palma FD, Regev A
Genome Res 29 (1) 53-63 [2019-01-00; online 2018-12-14]
The Role of VEGF in Controlling Vascular Permeability
Venkatraman L, Claesson-Welsh L
- - (-) 33-50 [2019-00-00; online 2019-10-01]
SA98GENETIC ANALYSIS OF CADM2, A POSSIBLE LINK BETWEEN MENTAL AND PHYSICAL HEALTH
Morris J, Bailey M, Baldassarre D, ..., Smith D, Strawbridge R
Eur Neuropsychopharmacol 29 (-) S1242 [2019-00-00; online 2019-00-00]
Retinoid-Related Orphan Nuclear Receptor RORB is Required for Saltatorial Locomotion in Rabbits
Carneiro M, Vieillard J, Andrade P, ..., Kullander K, Andersson L
- - (-) - [2019-00-00; online 2019-00-00]
Next-Generation Sequencing
Wiedmann M, Carroll LM
- - (-) 376-383 [2019-00-00; online 2019-00-00]
DDLS Fellow Laura Carroll
NF1 Regulates Mesenchymal Glioblastoma Plasticity and Aggressiveness Through the AP-1 Transcription Factor FOSL1
Marques C, Unterkircher T, Kroon P, ..., Carro MS, Squatrito M
SSRN Journal - (-) - [2019-00-00; online 2019-00-00]
Mitochondrion-Related Organelles in Free-Living Protists
Leger MM, Kolísko M, Stairs CW, Simpson AGB
- - (-) 287-308 [2019-00-00; online 2019-08-10]
Latest Advances in Solving the All-Pairs Suffix Prefix Problem
Rachid M
- - (-) 174-181 [2019-00-00; online 2019-00-00]
Kinetic Analysis of Carbonic Anhydrase–Sulfonamide Inhibitor Interactions
Talibov VO, Linkuvienė V, Danielson UH, Matulis D
- - (-) 125-140 [2019-00-00; online 2019-05-22]
Ion Mobility in Structural Biology
Allison TM, Landreh M
- - (-) 161-195 [2019-00-00; online 2019-00-00]
Experimental Models of Intestinal Inflammation: Lessons from Mouse and Zebrafish
Diaz OE, Morales RA, Das S, Villablanca EJ
- - (-) 47-76 [2019-00-00; online 2019-12-20]
Chemo-enzymatic pathways toward pinene-based renewable materials
Stamm A, Tengdelius M, Schmidt B, ..., Fogelström L, Malmström E
Green Chem. 21 (10) 2720-2731 [2019-00-00; online 2019-00-00]
Activation of Oncogenic Super-Enhancers Is Coupled with DNA Repair by RAD51
Hazan I, Monin J, Crosetto N, Aqeilan R
- - (-) - [2019-00-00; online 2019-00-00]
A Systems-Based Map of Human Brain Cell-Type Enriched Genes and Malignancy-Associated Endothelial Changes
Dusart P, Hallström BM, Renne T, ..., Uhlen M, Butler L
SSRN Journal - (-) - [2019-00-00; online 2019-00-00]

Publications 9.5.1