Publications 2024

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934 publications

DOI Crossref
Can we infer excitation-inhibition balance from the spectrum of population activity?
Chakravarty K, Roy S, Sinha A, Kumar A
- - (-) - [2024-12-30; online 2024-12-30]
PubMed DOI Crossref
The FunCoup Cytoscape App: multi-species network analysis and visualization.
Buzzao D, Steininger L, Guala D, Sonnhammer ELL
Bioinformatics 41 (1) - [2024-12-26; online 2024-12-19]
PubMed DOI Crossref
Correction for Wärnberg and Kumar, Feasibility of dopamine as a vector-valued feedback signal in the basal ganglia.
Proc. Natl. Acad. Sci. U.S.A. 121 (52) e2424183121 [2024-12-24; online 2024-12-16]
DOI Crossref
Evolutionary rescue of spherical mreB deletion mutants of the rod-shape bacterium Pseudomonas fluorescens SBW25
Yulo PRJ, Desprat N, Gerth ML, ..., Rainey PB, Hendrickson HL
- - (-) - [2024-12-23; online 2024-12-23]
PubMed DOI Crossref
Click chemistry-based dual nanosystem for microRNA-122 detection with single-base specificity from tumour cells.
Robles-Remacho A, Martos-Jamai I, Tabraue-Chávez M, ..., Diaz-Mochon JJ, Sanchez-Martin RM
J Nanobiotechnology 22 (1) 791 [2024-12-23; online 2024-12-23]
DOI Crossref
HAPP: High-Accuracy Pipeline for Processing deep metabarcoding data
Sundh J, Granqvist E, Iwaszkiewicz-Eggebrecht E, ..., Andersson AF, Ronquist F
- - (-) - [2024-12-22; online 2024-12-22]
PubMed DOI Crossref
Microbial Dynamics: Assessing Skincare Regimens' Impact on the Facial Skin Microbiome and Skin Health Parameters.
Wagner N, Valeriano VD, Diou-Hirtz S, ..., Schuppe-Koistinen I, Gillbro JM
Microorganisms 12 (12) - [2024-12-21; online 2024-12-21]
DOI Crossref
GenePioneer: A Comprehensive Python Package for Identification of Essential Genes and Modules in Cancer
Taheri G, Haerianardakani A
- - (-) - [2024-12-21; online 2024-12-21]
DDLS Fellow Golnaz Taheri
DOI Crossref
Ex Vivo Drug Responses and Molecular Profiles of 597 Pediatric Acute Lymphoblastic Leukemia Patients
Enblad AP, Krali O, Gezelius H, ..., Lönnerholm G, Nordlund J
- - (-) - [2024-12-20; online 2024-12-20]
PubMed DOI Crossref
Biologically inspired bioactive hydrogels for scarless corneal repair.
Huang J, Jiang T, Qie J, ..., Yao K, Han H
Sci Adv 10 (51) eadt1643 [2024-12-20; online 2024-12-18]
PubMed DOI Crossref
Molecular and functional profiling of primary normal ovarian cells defines insights into cancer development and drug responses.
Piki E, Dini A, Rantanen F, ..., Murumägi A, Ungureanu D
Mol Ther Oncol 32 (4) 200903 [2024-12-19; online 2024-11-08]
DOI Crossref
Crystallographic and NMR Study of Streptococcus pneumonia LCP Protein PsrSp Indicate the Importance of Dynamics in Four Long Loops for Ligand Specificity
Sandalova T, Sala BM, Moche M, ..., Agback P, Achour A
Crystals 14 (12) 1094 [2024-12-19; online 2024-12-19]
PubMed DOI Crossref
Paracentrotus lividus sea urchin gonadal extract mitigates neurotoxicity and inflammatory signaling in a rat model of Parkinson's disease.
Nagy NS, Helal M, Alsawy ES, ..., Al-Sherif SS, Essawy AE
PLoS ONE 19 (12) e0315858 [2024-12-18; online 2024-12-18]
DOI Crossref
Non-linear transcriptional responses to gradual modulation of transcription factor dosage
Domingo J, Minaeva M, Morris JA, ..., Sanjana NE, Lappalainen T
- - (-) - [2024-12-17; online 2024-12-17]
PubMed DOI Crossref
Flexible and robust cell type annotation for highly multiplexed tissue images.
Sun H, Yu S, Casals AM, ..., Lundberg E, Murphy RF
bioRxiv - (-) - [2024-12-17; online 2024-12-17]
PubMed DOI Crossref
Gaps between Open Science activities and actual recognition systems: Insights from an international survey.
Grattarola F, Shmagun H, Erdmann C, ..., Kim J, Mabile L
PLoS ONE 19 (12) e0315632 [2024-12-16; online 2024-12-16]
DOI Crossref
AI-first structural identification of pathogenic protein targets
Saluri M, Landreh M, Bryant P
- - (-) - [2024-12-16; online 2024-12-16]
PubMed DOI Crossref
Author Correction: AutoTransOP: translating omics signatures without orthologue requirements using deep learning.
Meimetis N, Pullen KM, Zhu DY, ..., Magliacane S, Lauffenburger DA
NPJ Syst Biol Appl 10 (1) 148 [2024-12-13; online 2024-12-13]
Avlant Nilsson DDLS Fellow
PubMed DOI Crossref
Neuropilin-1 controls vascular permeability through juxtacrine regulation of endothelial adherens junctions.
Pal S, Su Y, Nwadozi E, Claesson-Welsh L, Richards M
Angiogenesis 28 (1) 7 [2024-12-12; online 2024-12-12]
PubMed DOI Crossref
How to build the virtual cell with artificial intelligence: Priorities and opportunities.
Bunne C, Roohani Y, Rosen Y, ..., Leskovec J, Quake SR
Cell 187 (25) 7045-7063 [2024-12-12; online 2024-12-14]
PubMed DOI Crossref
CSF levels of brain-derived proteins correlate with brain ventricular volume in cognitively healthy 70-year-olds.
Bergström S, Mravinacová S, Lindberg O, ..., Skoog I, Månberg A
Clin Proteomics 21 (1) 65 [2024-12-12; online 2024-12-12]
DOI Crossref
The Role of BAZ2-dependent Chromatin Remodeling in Suppressing G4 DNA Structures and Associated Genomic Instability
Vandeuren AL, O’Dare K, Wilson RHC, ..., Reed SH, Day TA
- - (-) - [2024-12-11; online 2024-12-11]
PubMed DOI Crossref
EchoTilt: An Acoustofluidic Method for the Capture and Enrichment of Nanoplastics Directed Toward Drinking Water Monitoring.
Costa M, van der Geer L, Joaquim M, ..., Wiklund M, Russom A
Micromachines (Basel) 15 (12) - [2024-12-11; online 2024-12-11]
DOI Crossref
Activation of the ChvG-ChvI pathway promotes multiple survival strategies during cell wall stress in Agrobacterium tumefaciens
Bouchier JM, Knebel E, Amstutz J, ..., Cava F, Brown PJB
- - (-) - [2024-12-11; online 2024-12-11]
PubMed DOI Crossref
The impact of Parkinson's disease on striatal network connectivity and corticostriatal drive: An in silico study.
Carannante I, Scolamiero M, Hjorth JJJ, ..., Chachólski W, Kotaleski JH
Netw Neurosci 8 (4) 1149-1172 [2024-12-10; online 2024-12-10]
DOI Crossref
XRN1 supplies free nucleotides to feed alphavirus replication
Ruscica V, Iselin L, Hull R, ..., Davis I, Castello A
- - (-) - [2024-12-09; online 2024-12-09]
DOI Crossref
Pooled overexpression screening identifies PIPPI as a novel microprotein involved in the ER stress response
Lafranchi L, Spinner A, Hornisch M, ..., Piazza I, Elsässer SJ
- - (-) - [2024-12-09; online 2024-12-09]
PubMed DOI Crossref
From early methods for DNA diagnostics to genomes and epigenomes at high resolution during four decades - a personal perspective.
Syvänen AC
Ups. J. Med. Sci. 129 (-) - [2024-12-09; online 2024-12-09]
PubMed DOI Crossref
Elucidating acquired PARP inhibitor resistance in advanced prostate cancer.
Seed G, Beije N, Yuan W, ..., Carreira S, de Bono J
Cancer Cell 42 (12) 2113-2123.e4 [2024-12-09; online 2024-11-21]
Arian Lundberg DDLS Fellow
DOI Crossref
Plasma proteomics for novel biomarker discovery in childhood tuberculosis
Fossati A, Wambi P, Jaganath D, ..., Zar HJ, Swaney DL
- - (-) - [2024-12-08; online 2024-12-08]
Andrea Fossati DDLS Fellow
PubMed DOI Crossref
The Circulating Proteome─Technological Developments, Current Challenges, and Future Trends.
Geyer PE, Hornburg D, Pernemalm M, ..., Deutsch EW, Schwenk JM
J. Proteome Res. 23 (12) 5279-5295 [2024-12-06; online 2024-10-31]
PubMed DOI Crossref
Saltational Episodes of Reticulate Evolution in the Drosophila saltans Species Group.
Prediger C, Ferreira EA, Zorzato SV, ..., Yassin A, Madi-Ravazzi L
Mol. Biol. Evol. 41 (12) - [2024-12-06; online 2024-12-11]
PubMed DOI Crossref
"Head-to-Toe" Lipid Properties Govern the Binding and Cargo Transfer of High-Density Lipoprotein.
Weber F, Axmann M, Sezgin E, ..., Stangl H, Plochberger B
Membranes (Basel) 14 (12) - [2024-12-06; online 2024-12-06]
PubMed DOI Crossref
SARS-CoV-2 N protein recruits G3BP to double membrane vesicles to promote translation of viral mRNAs.
Long S, Guzyk M, Perez Vidakovics L, ..., Achour A, McInerney GM
Nat Commun 15 (1) 10607 [2024-12-05; online 2024-12-05]
PubMed DOI Crossref
A landscape of X-inactivation during human T cell development.
Gylemo B, Bensberg M, Hennings V, ..., Ekwall O, Nestor CE
Nat Commun 15 (1) 10527 [2024-12-04; online 2024-12-04]
Antonio Lentini DDLS Fellow
PubMed DOI Crossref
Improved Localization of Insulinomas Using 68Ga-NODAGA-Exendin-4 PET/CT.
Boss M, Eriksson O, Mikkola K, ..., Hermans J, Gotthardt M
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 65 (12) 1959-1964 [2024-12-03; online 2024-12-03]
PubMed DOI Crossref
Identification of SPP1 + macrophages as an immune suppressor in hepatocellular carcinoma using single-cell and bulk transcriptomics.
Jin H, Kim W, Yuan M, ..., Zhang C, Mardinoglu A
Front Immunol 15 (-) 1446453 [2024-12-03; online 2024-12-03]
PubMed DOI Crossref
Correction: Candidate serum protein biomarkers for active pulmonary tuberculosis diagnosis in tuberculosis endemic settings.
Ayalew S, Wegayehu T, Wondale B, ..., Fredolini C, Mihret A
BMC Infect Dis 24 (1) 1380 [2024-12-03; online 2024-12-03]
PubMed DOI Crossref
The paradox of predictability provides a bridge between micro- and macroevolution.
Tsuboi M, Sztepanacz J, De Lisle S, ..., Love AC, Houle D
J Evol Biol 37 (12) 1413-1432 [2024-12-02; online 2024-08-31]
DDLS Fellow Lisandro Milocco
PubMed DOI Crossref
Spc2 modulates substrate- and cleavage site-selection in the yeast signal peptidase complex.
Chung Y, Yim C, Pereira GP, ..., Souza PCT, Kim H
J. Cell Biol. 223 (12) - [2024-12-02; online 2024-11-20]
PubMed DOI Crossref
PET imaging of GABAA receptors in pancreatic islets by [11C]flumazenil.
Maloum-Rami F, Cheung P, Antoni G, ..., Eriksson O, Espes D
EJNMMI Res 14 (1) 122 [2024-12-02; online 2024-12-02]
PubMed DOI Crossref
Correction: Longitudinal assessment of reactivity and affinity profile of anti-Jo1 autoantibodies to distinct HisRS domains and a splice variant in a cohort of patients with myositis and anti-synthetase syndrome.
Notarnicola A, Preger C, Lundström SL, ..., Lundberg IE, Fernandes-Cerqueira C
Arthritis Res Ther 26 (1) 206 [2024-12-02; online 2024-12-02]
PubMed DOI Crossref
Characterising and preventing the gut microbiota's inactivation of trifluridine, a colorectal cancer drug.
McCoubrey LE, Shen C, Mwasambu S, ..., Globisch D, Basit AW
Eur J Pharm Sci 203 (-) 106922 [2024-12-01; online 2024-10-03]
Daniel Globisch SciLifeLab Fellow
DOI Crossref
Visual classification of tau‐PET detects four subtypes with different long‐term outcomes
Boccalini C, Mathoux G, Hristovska I, ..., Vogel JW, Garibotto V
Alzheimers Dement 20 (S2) - [2024-12-00; online 2025-01-09]
DOI Crossref
Unlocking Tau PET Accessibility: a Machine Learning‐Based Prediction of Tau Pathology from Plasma, MRI and Clinical Variables
Karlsson L, Vogel JW, Strandberg O, ..., Mattsson‐Carlgren N, Hansson O
Alzheimers Dement 20 (S2) - [2024-12-00; online 2025-01-09]
PubMed DOI Crossref
Ultra-processed food consumption, plasma metabolite profile, and risk of all-cause and cause-specific mortality in a population-based cohort.
Du Y, Zhang S, Schjølberg JS, ..., Sonestedt E, Borné Y
Clin Nutr 43 (12) 184-193 [2024-12-00; online 2024-10-20]
PubMed DOI Crossref
Transport mechanism of DgoT, a bacterial homolog of SLC17 organic anion transporters.
Dmitrieva N, Gholami S, Alleva C, ..., Alfonso-Prieto M, Fahlke C
EMBO J. 43 (24) 6740-6765 [2024-12-00; online 2024-10-25]
DOI Crossref
The mTOR‐4E‐BP1 axis controls microglia inflammatory and neurodegenerative responses
Bermudez S, Choi J, Kim S, ..., Healy LM, Sonenberg N
Alzheimers Dement 20 (S1) - [2024-12-00; online 2025-01-03]
PubMed DOI Crossref
The last of their kind: Is the genus Scutiger (Anura: Megophryidae) a relict element of the paleo-Transhimalaya biota?
Hofmann S, Podsiadlowski L, Andermann T, ..., Jablonski D, Schmidt J
Mol. Phylogenet. Evol. 201 (-) 108166 [2024-12-00; online 2024-08-09]
DDLS Fellow Tobias Andermann
DOI Crossref
Targeting Alzheimer's disease with novel dual-function 3,5-diaryl-4,5-dihydro-1H-pyrazole-1-carbothioamide derivatives
Katsogiannou A, Karta D, Di Stefano A, ..., Vassiliou S, Cacciatore I
European Journal of Medicinal Chemistry Reports 12 (-) 100235 [2024-12-00; online 2024-12-00]
PubMed DOI Crossref
Structural basis of LRPPRC-SLIRP-dependent translation by the mitoribosome.
Singh V, Moran JC, Itoh Y, ..., Barrientos A, Amunts A
Nat. Struct. Mol. Biol. 31 (12) 1838-1847 [2024-12-00; online 2024-08-12]
PubMed DOI Crossref
SenNet recommendations for detecting senescent cells in different tissues.
Suryadevara V, Hudgins AD, Rajesh A, ..., Dou Z, Neretti N
Nat. Rev. Mol. Cell Biol. 25 (12) 1001-1023 [2024-12-00; online 2024-06-03]
Sanja Vickovic SciLifeLab Fellow
PubMed DOI Crossref
Role of human plasma metabolites in prediabetes and type 2 diabetes from the IMI-DIRECT study.
Sharma S, Dong Q, Haid M, ..., Pearson ER, Grallert H
Diabetologia 67 (12) 2804-2818 [2024-12-00; online 2024-09-30]
PubMed DOI Crossref
Risk factors for Charcot foot development in individuals with diabetes mellitus.
Tsatsaris G, Rajamand Ekberg N, Fall T, Catrina SB
Diabetologia 67 (12) 2702-2710 [2024-12-00; online 2024-09-13]
PubMed DOI Crossref
Reviewability and supportability: New complementary principles to empower research software practices.
Zhang H, Maillo A, Khan SA, ..., Gomez-Cabrero D, Tegnér J
Comput Struct Biotechnol J 23 (-) 3989-3998 [2024-12-00; online 2024-11-06]
DOI Crossref
Regional Amyloid Load Predicts Tau and Atrophy Dynamics
Chaggar P, Vogel JW, Binette AP, ..., Hansson O, Goriely A
Alzheimers Dement 20 (S2) - [2024-12-00; online 2025-01-09]
DOI Crossref
Proteomics analysis characterizing new markers related to Aβ plaques and tau tangles pathologies
Binette AP, Wennström M, Strandberg O, ..., Vogel JW, Hansson O
Alzheimers Dement 20 (S2) - [2024-12-00; online 2025-01-09]
PubMed DOI Crossref
Probe set selection for targeted spatial transcriptomics.
Kuemmerle LB, Luecken MD, Firsova AB, ..., Samakovlis C, Theis FJ
Nat. Methods 21 (12) 2260-2270 [2024-12-00; online 2024-11-18]
PubMed DOI Crossref
Optimising in-cell NMR acquisition for nucleic acids.
Annecke HTP, Eidelpes R, Feyrer H, ..., Dasgupta R, Petzold K
J Biomol NMR 78 (4) 249-264 [2024-12-00; online 2024-08-20]
PubMed DOI Crossref
Novel tetrahydronaphthalen-1-yl-phenethyl ureas: synthesis and dual antibacterial-anticancer activities.
Akbaba Y, Kacı FN, Arslan ME, ..., Mardinoğlu A, Türkez H
J Enzyme Inhib Med Chem 39 (1) 2286925 [2024-12-00; online 2023-12-07]
PubMed DOI Crossref
New developments for the Quest for Orthologs benchmark service.
Altenhoff A, Nevers Y, Tran V, ..., Ebersberger I, Sonnhammer E
NAR Genomics and Bioinformatics 6 (4) lqae167 [2024-12-00; online 2024-12-11]
DOI Crossref
Multiplex detection of meningitis pathogens by a vertical flow paper microarray and signal enhancement suitable for low-resource settings: Proof of concept
Réu P, Gaudenzi G, Nanjebe D, ..., Boum II Y, Russom A
Talanta Open 10 (-) 100357 [2024-12-00; online 2024-12-00]
DOI Crossref
Individual variation in proteomic cascades along the Alzheimer’s disease spectrum
Vogel JW, Vilkaite G, Binette AP, ..., Mattsson‐Carlgren N, Hansson O
Alzheimers Dement 20 (S2) - [2024-12-00; online 2025-01-09]
DOI Crossref
Improved precision of Alzheimer’s disease fluid biomarkers when using Amyloid‐β40 or non‐phosphorylated tau as a reference
Karlsson L, Janelidze S, Horie K, ..., Mattsson‐Carlgren N, Hansson O
Alzheimers Dement 20 (S2) - [2024-12-00; online 2025-01-09]
DOI Crossref
Impact of regional MAPT, APOE, and Aβ on tau propagation in Alzheimer’s disease: Insights from a connectome‐based simulation model
Xiao Y, Strandberg O, Bazinet V, ..., Hansson O, Vogel JW
Alzheimers Dement 20 (S8) - [2024-12-00; online 2025-01-09]
PubMed DOI Crossref
Exploratory insights from the immuno-oncology hollow fiber assay: A pilot approach bridging In Vitro and In Vivo models.
Selvin T, Berglund M, Åkerström A, ..., Andersson CR, Fryknäs M
SLAS Technol 29 (6) 100232 [2024-12-00; online 2024-12-03]
PubMed DOI Crossref
Emerging mutation in SARS-CoV-2 facilitates escape from NK cell recognition and associates with enhanced viral fitness.
Bilev E, Wild N, Momayyezi P, ..., Achour A, Hammer Q
PLoS Pathog 20 (12) e1012755 [2024-12-00; online 2024-12-09]
PubMed DOI Crossref
Early detection of pancreatic cancer: Study design and analytical considerations in biomarker discovery and early phase validation studies.
Smith LM, Mahoney DW, Bamlet WR, ..., Koay EJ, Oberg AL
Pancreatology 24 (8) 1265-1279 [2024-12-00; online 2024-10-29]
DDLS Fellow Qiaoli Wang
PubMed DOI Crossref
Diagnosing Monogenic Stroke at Younger Age.
Ilinca A, Kafantari E, Wallenius J, ..., Puschmann A, Lindgren AG
Stroke 55 (12) 2846-2855 [2024-12-00; online 2024-11-05]
DOI Crossref
Designing from biobased to closed-loop circularity: Flexible dynamic polyimine-amide networks
Subramaniyan S, Zhang B, Syrén PO, Hakkarainen M
Chem Eng J 501 (-) 157632 [2024-12-00; online 2024-12-00]
DOI Crossref
Data‐driven progression patterns of Aβ, tau, α‐synuclein and vascular pathology in a clinical population
Mastenbroek SE, Collij LE, Vogel JW, ..., Ossenkoppele R, Hansson O
Alzheimers Dement 20 (S2) - [2024-12-00; online 2025-01-09]
PubMed DOI Crossref
Cyclophilin D plays a critical role in the survival of senescent cells.
Protasoni M, López-Polo V, Stephan-Otto Attolini C, ..., Kovatcheva M, Serrano M
EMBO J. 43 (23) 5972-6000 [2024-12-00; online 2024-10-24]
PubMed DOI Crossref
CopyMix: Mixture model based single-cell clustering and copy number profiling using variational inference.
Safinianaini N, De Souza CPE, Roth A, ..., Toosi H, Lagergren J
Comput Biol Chem 113 (-) 108257 [2024-12-00; online 2024-10-23]
DOI Crossref
Benzylhydroxamic acids as inhibitors of insulin regulated aminopeptidase (IRAP)
Beveridge J, Söderström M, Prieto-Díaz R, ..., Larhed M, Gising J
European Journal of Medicinal Chemistry Reports 12 (-) 100215 [2024-12-00; online 2024-12-00]
PubMed DOI Crossref
Author Correction: A virally encoded tRNA neutralizes the PARIS antiviral defence system.
Burman N, Belukhina S, Depardieu F, ..., Wiedenheft B, Isaev A
Nature 636 (8043) E8 [2024-12-00; online 2024-12-05]
PubMed DOI Crossref
A framework for sharing of clinical and genetic data for precision medicine applications.
Elhussein A, Baymuradov U, NYGC ALS Consortium , ..., Natarajan K, Gürsoy G
Nat. Med. 30 (12) 3578-3589 [2024-12-00; online 2024-09-03]
DOI Crossref
Deteriorated mechanics of left ventricular diastolic filling one year after coronary artery bypass grafting
Norderfeldt J, Sundqvist MG, Maret E, ..., Eriksson MJ, Ugander M
- - (-) - [2024-11-29; online 2024-11-29]
PubMed DOI Crossref
Aquaporin-4 as a cerebrospinal fluid biomarker of Alzheimer's disease.
Gómez de San José N, Halbgebauer S, Steinacker P, ..., Parnetti L, Otto M
Transl Neurodegener 13 (1) 57 [2024-11-29; online 2024-11-29]
PubMed DOI Crossref
The ROCK-1/2 inhibitor RKI-1447 blocks N-MYC, promotes cell death, and emerges as a synergistic partner for BET inhibitors in neuroblastoma.
Pepich A, Tümmler C, Abu Ajamieh S, ..., Johnsen JI, Wickström M
Cancer Lett. 605 (-) 217261 [2024-11-28; online 2024-09-20]
PubMed DOI Crossref
Sparse Neighbor Joining: rapid phylogenetic inference using a sparse distance matrix.
Kurt S, Bouchard-Côté A, Lagergren J
Bioinformatics 40 (12) - [2024-11-28; online 2024-11-21]
PubMed DOI Crossref
Author Correction: Integration of whole-body [18F]FDG PET/MRI with non-targeted metabolomics can provide new insights on tissue-specific insulin resistance in type 2 diabetes.
Diamanti K, Visvanathar R, Pereira MJ, ..., Wadelius C, Ahlström H
Sci Rep 14 (1) 29632 [2024-11-28; online 2024-11-28]
PubMed DOI Crossref
A Swedish dietary guideline index, gut microbial α-diversity and prevalence of metabolic syndrome - observations in the Swedish CArdioPulmonary bioImage Study (SCAPIS).
Ericson U, Hellstrand S, Larsson A, ..., Fall T, Orho-Melander M
Food Nutr Res 68 (-) - [2024-11-28; online 2024-11-28]
PubMed DOI Crossref
Maintenance of cell wall remodeling and vesicle production are connected in Mycobacterium tuberculosis.
Salgueiro V, Bertol J, Gutierrez C, ..., Sanz J, Prados-Rosales R
bioRxiv - (-) - [2024-11-27; online 2024-11-27]
PubMed DOI Crossref
Cryo-EM structure of single-layered nucleoprotein-RNA complex from Marburg virus.
Zinzula L, Beck F, Camasta M, ..., Plitzko JM, Baumeister W
Nat Commun 15 (1) 10307 [2024-11-27; online 2024-11-27]
PubMed DOI Crossref
Contemporary menopausal hormone therapy and risk of cardiovascular disease: Swedish nationwide register based emulated target trial.
Johansson T, Karlsson T, Bliuc D, ..., Center JR, Johansson Å
BMJ 387 (-) e078784 [2024-11-27; online 2024-11-27]
PubMed DOI Crossref
The association between novel urinary kidney damage biomarkers and coronary atherosclerosis in an apparently healthy population.
Lin YT, Wuopio J, Larsson A, ..., Fall T, Ärnlöv J
Sci Rep 14 (1) 29215 [2024-11-25; online 2024-11-25]
DOI Crossref
Microneedles loaded with lipid nanocarriers for local treatment of vulvovaginal candidiasis
Udayakumar P, Škalko-Basnet N, Salas Cotaquispe CF, ..., Du J, Teleki A
- - (-) - [2024-11-25; online 2024-11-25]
Alexandra Teleki SciLifeLab Fellow
PubMed DOI Crossref
Co-occurring mutations identify prognostic subgroups of microsatellite stable colorectal cancer.
Nunes L, Stenersen JM, Kryeziu K, ..., Lothe RA, Sveen A
Mol Cancer 23 (1) 264 [2024-11-25; online 2024-11-25]
PubMed DOI Crossref
Naltrexone blocks alcohol-induced effects on kappa-opioid receptors in the plasma membrane.
Oasa S, Sezgin E, Ma Y, ..., Vukojević V, Terenius L
Transl Psychiatry 14 (1) 477 [2024-11-24; online 2024-11-24]
PubMed DOI Crossref
The early transcriptional and post-transcriptional responses to fluconazole in sensitive and resistant Candida albicans.
Stevens I, Silao FG, Huch S, ..., Ljungdahl PO, Pelechano V
Sci Rep 14 (1) 29012 [2024-11-22; online 2024-11-22]
SciLifeLab Fellow Vicent Pelechano
PubMed DOI Crossref
Response to Letter to Editor by A. Derbalah et al.: the role of automation in enhancing reproducibility and interoperability of PBPK models.
Domínguez-Romero E, Mazurenko S, Scheringer M, ..., Županič A, Suarez-Diez M
Brief. Bioinformatics 26 (1) - [2024-11-22; online 2025-02-10]
PubMed DOI Crossref
Bridging the gap: Integrating cutting-edge techniques into biological imaging with deepImageJ.
Fuster-Barceló C, García-López-de-Haro C, Gómez-de-Mariscal E, ..., Sage D, Muñoz-Barrutia A
Biol Imaging 4 (-) e14 [2024-11-22; online 2024-11-22]
PubMed DOI Crossref
Flipping a switch on BRD4: How to control the do-it-all.
van Hout FAH, Vihervaara A
Mol. Cell 84 (22) 4257-4259 [2024-11-21; online 2024-11-23]
Anniina Vihervaara SciLifeLab Fellow
PubMed DOI Crossref
Single-molecule states link transcription factor binding to gene expression.
Doughty BR, Hinks MM, Schaepe JM, ..., Bintu L, Greenleaf WJ
Nature - (-) - [2024-11-20; online 2024-11-20]
Emil Marklund SciLifeLab Fellow
PubMed DOI Crossref
SARS-CoV-2 and HSV-1 Induce Amyloid Aggregation in Human CSF Resulting in Drastic Soluble Protein Depletion.
Christ W, Kapell S, Sobkowiak MJ, ..., El Andaloussi S, Ezzat K
ACS Chem Neurosci 15 (22) 4095-4104 [2024-11-20; online 2024-11-07]
PubMed DOI Crossref
Complete genome sequences of the prosthecate dimorphic bacteria Brevundimonas intermedia CB63T and Brevundimonas staleyi FWC43T.
Hallgren J, Daneby F, Jonas K
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Annotated genome sequences of Salmonella Haifa, Salmonella Bangkok, and Salmonella Reading, isolated from chicken meat in South Africa.
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Single cell long read whole genome sequencing reveals somatic transposon activity in human brain.
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Standalone single- and bi-layered human skin 3D models supported by recombinant silk feature native spatial organization.
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Plasma Proteomics Differentiates between Patients with B-Cell Lymphomas
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Mutations in BCORCCND2NRAS and XPO1 Predict Clinical Outcomes upon MRD-Guided Venetoclax Plus Ibrutinib in Relapsed and Refractory Chronic Lymphocytic Leukemia
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Mutation-Specific Differences in the Relationship between Obesity and Clonal Hematopoiesis, with a Focus on JAK2V617F and MPN Prevention
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Mapping the Spatial Proteome of Individual Leukemia Cells Undergoing Fludarabine Treatment
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Differential Response to ATR/Chk1 Inhibition in Preleukemia and Transformed Leukemia in an MLL-ENL Model of Leukemogenesis Reflects Enrichment for Myc-Transcriptional Program
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Deciphering the Heterogeneity of Acute Myeloid Leukemia through Chromatin Accessibility Profiling
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Clinical Relevance of the Integrative Analysis of Gut Microbiome and Metabolomics in Myeloid Neoplasms: Correlations with Genomic Profiles, Treatment Response/Complications and Clinical Outcome
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CCDC28A deficiency causes head-tail coupling defects and immotility in murine spermatozoa.
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BMI trajectories from birth to young adulthood associate with distinct cardiometabolic profiles.
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A PERTURBATION CELL ATLAS OF HUMAN INDUCED PLURIPOTENT STEM CELLS.
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Prelude to malignancy: A gene expression signature in normal mammary gland from breast cancer patients suggests pre-tumorous alterations and is associated with adverse outcomes.
Andreou M, Jąkalski M, Duzowska K, ..., Mieczkowski J, Piotrowski A
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EMhub: a web platform for data management and on-the-fly processing in scientific facilities.
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The genetic landscape of neuro-related proteins in human plasma.
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Sustained immune activation and impaired epithelial barrier integrity in the ectocervix of women with chronic HIV infection.
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Photothermal induction of pyroptosis in malignant glioma spheroids using (16-mercaptohexadecyl)trimethylammonium bromide-modified cationic gold nanorods.
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Massive parallel sequencing-based non-invasive prenatal test (NIPT) identifies aberrations on chromosome 13.
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Loss of heterozygosity of CYP2D6 enhances the sensitivity of hepatocellular carcinomas to talazoparib.
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EBioMedicine 109 (-) 105368 [2024-11-00; online 2024-10-04]
Daniel Globisch SciLifeLab Fellow
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Integration across biophysical scales identifies molecular and cellular correlates of person-to-person variability in human brain connectivity.
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Epigenetic regulation by polycomb repressive complex 1 promotes cerebral cavernous malformations.
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Early-life chemical exposome: Comprehensive strategies for wide-scope screening of organic compounds
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Detach-ROCKET: sequential feature selection for time series classification with random convolutional kernels
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Nat. Methods 21 (11) 2008-2012 [2024-11-00; online 2024-10-21]
DDLS Fellow Kaisa Thorell
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Boric Acid and Borax Protect Human Lymphocytes from Oxidative Stress and Genotoxicity Induced by 3-Monochloropropane-1,2-diol.
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Automated multiplexed affinity-based enrichment of peptides for LC-MS/MS plasma proteomics.
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Author Correction: Androgen receptor pathway inhibitors and taxanes in metastatic prostate cancer: an outcome-adaptive randomized platform trial.
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Antibody-displaying extracellular vesicles for targeted cancer therapy.
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An ancient ecospecies of Helicobacter pylori.
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Nature 635 (8037) 178-185 [2024-11-00; online 2024-10-16]
DDLS Fellow Kaisa Thorell
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Aberrant overexpression of myosin 1b in glioblastoma promotes angiogenesis via VEGF-myc-myosin 1b-Piezo1 axis.
Lv W, Yang F, Ge Z, ..., Jiang X, Zhang Y
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351 Enhancing mesothelin-CAR T cell efficacy in ovarian cancer: the role of drug combinations
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Yuan M, Mardinoglu A
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Multi-omics characterization of lymphedema-induced adipose tissue resulting from breast cancer-related surgery.
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Genomic codes governing enhancer RNA fate
Yip CW, Parr C, Takahashi H, ..., Hon CC, Carninci P
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Time-resolved scattering methods for biological samples at the CoSAXS beamline, MAX IV Laboratory.
Herranz-Trillo F, Sørensen HV, Dicko C, ..., Lerato M, Terry AE
Meth. Enzymol. 709 (-) 245-296 [2024-10-30; online 2024-10-30]
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Protumoral lipid droplet-loaded macrophages are enriched in human glioblastoma and can be therapeutically targeted.
Governa V, de Oliveira KG, Bång-Rudenstam A, ..., Bengzon J, Belting M
Sci Transl Med 16 (771) eadk1168 [2024-10-30; online 2024-10-30]
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PKLR-modulating compounds show promising effects for the treatment of hepatocellular carcinoma
Mardinoglu A, Kim W, Jin H, ..., Shi X, Zhang C
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Mechanisms conferring bacterial cell wall variability and adaptivity.
Torrens G, Cava F
Biochem. Soc. Trans. 52 (5) 1981-1993 [2024-10-30; online 2024-09-26]
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A dynamic 3D polymer model of the Escherichia coli chromosome driven by data from optical pooled screening
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Identifying Hub Genes and Metabolic Pathways in Collagen VI-Related Dystrophies: A Roadmap to Therapeutic Intervention.
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Biomolecules 14 (11) - [2024-10-29; online 2024-10-29]
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The ABCF ATPase New1 resolves translation termination defects associated with specific tRNAArg and tRNALys isoacceptors in the P site.
Turnbull K, Paternoga H, von der Weth E, ..., Wilson DN, Hauryliuk V
Nucleic Acids Res. 52 (19) 12005-12020 [2024-10-28; online 2024-09-01]
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Data of the Insect Biome Atlas: a metabarcoding survey of the terrestrial arthropods of Sweden and Madagascar
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Smartphone-driven centrifugal microfluidics for diagnostics in resource limited settings.
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Biomed Microdevices 26 (4) 43 [2024-10-26; online 2024-10-26]
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Optimized method for fluorine-18 radiolabeling of Affibody molecules using RESCA.
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Sequence-dependent scale for translocon-mediated insertion of interfacial helices in membranes
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Novel Approach for Lifetime-Proportional Luminescence Imaging Using Frame Straddling.
Ahmerkamp S, Pacherres CO, Mosshammer M, ..., Koren K, Kühl M
ACS Sens 9 (10) 5531-5540 [2024-10-25; online 2024-10-14]
Lars Behrendt SciLifeLab Fellow
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Mitochondrial ETF insufficiency drives neoplastic growth by selectively optimizing cancer bioenergetics
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Discovery of a Series of Macrocycles as Potent Inhibitors of Leishmania Infantum.
Riu F, Ruppitsch LA, Duy Vo D, ..., Sjö P, Kihlberg J
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The energy metabolism of Cupriavidus necator in different trophic conditions.
Jahn M, Crang N, Gynnå AH, ..., Charpentier E, Hudson EP
Applied and environmental microbiology 90 (10) e0074824 [2024-10-23; online 2024-09-25]
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Homologous Peptide Foldamer Promotes FUS Aggregation and Triggers Cancer Cell Death.
Wang MD, Yi L, Li Y, ..., Liu C, Wang H
Journal of the American Chemical Society 146 (42) 28669-28676 [2024-10-23; online 2024-10-15]
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A unique metabolic gene cluster regulates lactose and galactose metabolism in the yeast Candida intermedia.
Peri KVR, Yuan L, Faria Oliveira F, ..., Kerkhoven EJ, Geijer C
Applied and environmental microbiology 90 (10) e0113524 [2024-10-23; online 2024-09-06]
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Fish are poor sentinels for surveillance of riverine AMR
Tskhay F, Köbsch C, Elena AX, ..., Berendonk TU, Klümper U
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DDLS Fellow Johan Bengtsson-Palme
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Bacterial spore surface nanoenvironment requires a AAA+ ATPase to promote MurG function.
Delerue T, Updegrove TB, Chareyre S, ..., Aravind L, Ramamurthi KS
Proc. Natl. Acad. Sci. U.S.A. 121 (43) e2414737121 [2024-10-22; online 2024-10-15]
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Crystallographic and NMR studies of Streptococcus pneumonia LCP protein Psr Sp indicate the importance of dynamics in four long loops for ligand specificity
Sandalova T, Sala BM, Moche M, ..., Agback P, Achour A
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Synthesis, Characterization, Theoretical Studies and in Vitro Embriyotoxic, Genotoxic and Anticancer Effects of Novel Phenyl(1,4,6-Triphenyl-2-Thioxo-1,2,3,4-Tetrahydropyrimidin-5-yl)Methanone
Akbas E, Othman KA, Çelikezen FÇ, ..., Yapca OE, Mardinoglu A
Polycyclic Aromatic Compounds 44 (9) 6284-6301 [2024-10-20; online 2023-11-03]
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Distinct molecular profiles and shared drug vulnerabilities in pancreatic metastases of renal cell carcinoma.
Roos-Mattila M, Kallio P, Luck TJ, ..., Pietiäinen VM, Seppänen HE
Commun Biol 7 (1) 1355 [2024-10-20; online 2024-10-20]
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Symmetry-adapted Markov state models of closing, opening, and desensitizing in α 7 nicotinic acetylcholine receptors.
Zhuang Y, Howard RJ, Lindahl E
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OS09.5.A UNEXPECTED FUNCTIONAL ROLE OF GLYCOCALYX ENCAPSULATION DURING GBM METABOLIC ADAPTATION OPENS AVENUES FOR NEW TREATMENT CONCEPTS
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Neuro-oncology 26 (Supplement_5) v26-v26 [2024-10-17; online 2024-10-17]
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snPATHO-seq, a versatile FFPE single-nucleus RNA sequencing method to unlock pathology archives.
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Commun Biol 7 (1) 1340 [2024-10-16; online 2024-10-16]
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Temperature, sediment resuspension, and salinity drive the prevalence of Vibrio vulnificus in the coastal Baltic Sea.
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MBio 15 (10) e0156924 [2024-10-16; online 2024-09-19]
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ESPressoscope: A small and powerful approach for in situ microscopy.
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Contributions of DNA Sequencing Technologies to the Integrative Monitoring of Karstic Caves
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VISION - an open-source software for automated multi-dimensional image analysis of cellular biophysics.
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Machine learning in microscopy - insights, opportunities and challenges.
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IN VIVO APPLICATION OF LOCAL DRUG DELIVERY SYSTEMS AGAINST MEDULLOBLASTOMA GROUP 3 AND ATYPICAL/TERATOID/RHABOID TUMOURS
Moloney DC, McCrorie DP, ElSherbeny MA, ..., Smith DS, Rahman DR
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Autoinflammation in patients with leukocytic CBL loss of heterozygosity is caused by constitutive ERK-mediated monocyte activation.
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Secondary Binding Site of CYP17A1 in Enhanced Sampling Simulations.
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Resilience of genetic diversity in forest trees over the Quaternary.
Milesi P, Kastally C, Dauphin B, ..., Pyhäjärvi T, GenTree Consortium
Nat Commun 15 (1) 8538 [2024-10-14; online 2024-10-14]
Pascal Milesi SciLifeLab Fellow
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Metagenomic assemblies tend to break around antibiotic resistance genes.
Abramova A, Karkman A, Bengtsson-Palme J
BMC Genomics 25 (1) 959 [2024-10-14; online 2024-10-14]
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Combining Data-Driven and Structure-Based Approaches in Designing Dual PARP1-BRD4 Inhibitors for Breast Cancer Treatment.
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J Chem Inf Model 64 (19) 7725-7742 [2024-10-14; online 2024-09-18]
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Coagulation factor X promotes resistance to androgen-deprivation therapy in prostate cancer.
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Cancer Cell 42 (10) 1676-1692.e11 [2024-10-14; online 2024-09-19]
Arian Lundberg DDLS Fellow
PubMed DOI Crossref
Characterization of Nuclear Mitochondrial Insertions in Canine Genome Assemblies.
Schall PZ, Meadows JRS, Ramos-Almodovar F, Kidd JM
Genes (Basel) 15 (10) - [2024-10-14; online 2024-10-14]
PubMed DOI Crossref
Methotrexate promotes the release of granulocyte-macrophage colony-stimulating factor from rheumatoid arthritis fibroblast-like synoviocytes via autocrine interleukin-1 signaling.
Bergström B, Selldén T, Bollmann M, Svensson MND, Ekwall AH
Arthritis Res Ther 26 (1) 178 [2024-10-11; online 2024-10-11]
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Maintenance of cell wall remodeling and vesicle production are connected in Mycobacterium tuberculosis
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Isotope Encoded chemical Imaging Identifies Amyloid Plaque Age Dependent Structural Maturation, Synaptic Loss, and Increased Toxicity.
Wood JI, Dulewicz M, Ge J, ..., Edwards FA, Hanrieder J
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DOI Crossref
Properties and limitations of eDNA substrates for terrestrial animal monitoring
Zhao B, Andermann T
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DDLS Fellow Tobias Andermann
PubMed DOI Crossref
New connections of medication use and polypharmacy with the gut microbiota composition and functional potential in a large population.
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Deep plasma proteomics identifies and validates an eight-protein biomarker panel that separate benign from malignant tumors in ovarian cancer
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SlipO2Chip - single-cell respiration under tuneable environments.
Cui Y, Moreira MA, Whalen KE, ..., Tenje M, Behrendt L
Lab Chip 24 (20) 4786-4797 [2024-10-09; online 2024-10-09]
Lars Behrendt SciLifeLab Fellow
PubMed DOI Crossref
Quest for Orthologs in the Era of Biodiversity Genomics.
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Genome Biol Evol 16 (10) - [2024-10-09; online 2024-10-15]
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In Situ Functionalization of Polar Polythiophene-Based Organic Electrochemical Transistor to Interface In Vitro Models.
Buchmann S, Stoop P, Roekevisch K, ..., Zeglio E, Herland A
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PubMed DOI Crossref
Peripartum depression symptom trajectories, telomere length and genotype, and adverse childhood experiences.
Vrettou M, Lager S, Toffoletto S, ..., Skalkidou A, Comasco E
BMC Psychiatry 24 (1) 661 [2024-10-08; online 2024-10-08]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Identification of novel and potent inhibitors of SARS-CoV-2 main protease from DNA-encoded chemical libraries.
Akaberi D, Pourghasemi Lati M, Krambrich J, ..., Verho O, Lennerstrand J
Antimicrob. Agents Chemother. 68 (10) e0090924 [2024-10-08; online 2024-08-28]
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Call for Papers for a Special Issue on “Ocean Health”
Dachs J, Boehm A, Sunderland E, ..., Schlenk D, Brooks B
Environ Sci Technol Lett 11 (10) 1016-1016 [2024-10-08; online 2024-10-08]
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Call for Papers for a Special Issue on “Ocean Health”
Dachs J, Boehm A, Sunderland E, ..., Schlenk D, Brooks B
Environ. Sci. Technol. 58 (40) 17523-17523 [2024-10-08; online 2024-10-08]
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LOW COST, PORTABLE DNA NANOBALL AMPLIFICATION KIT TO INTEGRATE WITH AND PERFORM LAMP REACTION IN A POINT-OF-CARE DIGITAL ASSAY FOR RAPID ELECTRONIC QUANTIFICATION OF CLINICAL PATHOGENS USING DNA NANOBALLS
Karimi K, Barrett D, Chille E, ..., Pelechano V, Javanmard M
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Genetic Adaptation to Amoxicillin inEscherichia coli: The Limited Role ofdinBandkatE
Teichmann L, Wenne M, Luitwieler S, ..., Bengtsson-Palme J, Kuile Bt
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DDLS Fellow Johan Bengtsson-Palme
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Beyond Tumors: Reduced survival linked to pathogenic PIK3CA and TP53 post-zygotic variants in the uninvolved breast tissue of recurrent cancer patients
Andreou M, Chojnowska K, Filipowicz N, ..., Dumanski JP, Piotrowski A
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A genotype-first approach identifies variants for orofacial clefts and other phenotypes in dogs
Buckley RM, Bilgen N, Harris AC, ..., Boyko AR, Ostrander EA
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Quantification of Anisotropy in Exchange and Dispersion Interactions: A Simple Model for Physics-Based Force Fields.
Kříž K, van der Spoel D
J Phys Chem Lett 15 (39) 9974-9978 [2024-10-03; online 2024-09-24]
PubMed DOI Crossref
Multiplexed chromatin immunoprecipitation sequencing for quantitative study of histone modifications and chromatin factors.
Kumar B, Navarro C, Yung PYK, ..., Martin M, Elsässer SJ
Nat Protoc - (-) - [2024-10-03; online 2024-10-03]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Genetics of immune response to Epstein-Barr virus: prospects for multiple sclerosis pathogenesis.
Huang J, Tengvall K, Lima IB, ..., Olsson T, Kockum I
Brain 147 (10) 3573-3582 [2024-10-03; online 2024-04-17]
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A thermoplastic chip for correlative assays combining screening and high-resolution imaging of immune cell responses
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Dimensionality Reduction of Genetic Data using Contrastive Learning
Thor F, Nettelblad C
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PubMed DOI Crossref
Unveiling the Molecular Mechanisms of Glioblastoma through an Integrated Network-Based Approach.
Kaynar A, Kim W, Ceyhan AB, ..., Shoaie S, Mardinoglu A
Biomedicines 12 (10) - [2024-10-01; online 2024-10-01]
PubMed DOI Crossref
Spatial Transcriptome Mapping of the Desmoplastic Growth Pattern of Colorectal Liver Metastases by In Situ Sequencing Reveals a Biologically Relevant Zonation of the Desmoplastic Rim.
Andersson A, Escriva Conde M, Surova O, ..., Nilsson M, Nyström H
Clin. Cancer Res. 30 (19) 4517-4529 [2024-10-01; online 2024-07-26]
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Lamins regulate nuclear mechanics and shape to control glioblastoma cell proliferation, migration and invasion
Wang X, Pereira D, Perfettini I, ..., Etienne-Manneville S, Manneville JB
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IL-7-dependent and -independent lineages of IL-7R-dependent human T cells.
Arango-Franco CA, Ogishi M, Unger S, ..., Casanova JL, Puel A
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Gene expression-phenotype association study reveals the dual role of TNF-α/TNFR1 signaling axis in confined breast cancer cell migration.
Cruceriu D, Balacescu L, Baldasici O, ..., Irimia D, Tudoran O
Life Sci 354 (-) 122982 [2024-10-01; online 2024-08-14]
PubMed DOI Crossref
Evaluation of Nontargeted Mass Spectral Data Acquisition Strategies for Water Analysis and Toxicity-Based Feature Prioritization by MS2Tox.
Peets P, Rian MB, Martin JW, Kruve A
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Engineered modular neuronal networks-on-chip represent structure-function relationship.
Habibey R, Striebel J, Meinert M, ..., Nasiri R, Latifi S
Biosens Bioelectron 261 (-) 116518 [2024-10-01; online 2024-06-22]
PubMed DOI Crossref
Chloroplastic ascorbate modifies plant metabolism and may act as a metabolite signal regardless of oxidative stress.
Tóth D, Tengölics R, Aarabi F, ..., Papp B, Tóth SZ
Plant Physiol. 196 (2) 1691-1711 [2024-10-01; online 2024-08-06]
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Yeast9: a consensus genome-scale metabolic model for S. cerevisiae curated by the community.
Zhang C, Sánchez BJ, Li F, ..., Lu H, Kerkhoven EJ
Mol Syst Biol 20 (10) 1134-1150 [2024-10-00; online 2024-08-12]
PubMed DOI Crossref
The genomes of all lungfish inform on genome expansion and tetrapod evolution.
Schartl M, Woltering JM, Irisarri I, ..., Schneider I, Meyer A
Nature 634 (8032) 96-103 [2024-10-00; online 2024-08-14]
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The genetic architecture of repeated local adaptation to climate in distantly related plants.
Whiting JR, Booker TR, Rougeux C, ..., Zhou L, Yeaman S
Nat Ecol Evol 8 (10) 1933-1947 [2024-10-00; online 2024-08-26]
Pascal Milesi SciLifeLab Fellow
PubMed DOI Crossref
The ACROBAT 2022 challenge: Automatic registration of breast cancer tissue.
Weitz P, Valkonen M, Solorzano L, ..., Ruusuvuori P, Rantalainen M
Med Image Anal 97 (-) 103257 [2024-10-00; online 2024-07-01]
DDLS Fellow Kimmo Kartasalo
PubMed DOI Crossref
The 'queen of the Andes' (Puya raimondii) is genetically fragile and fragmented: a consequence of long generation time and semelparity?
Liu L, James J, Zhang Y, ..., Lascoux M, Ge X
New Phytol. 244 (1) 277-291 [2024-10-00; online 2024-08-12]
DDLS Fellow Jennifer James
PubMed DOI Crossref
Structure prediction analysis of human core TIM23 complex reveals conservation of the protein translocation mechanism.
Maruszczak KK, Draczkowski P, Wnorowski A, Chacinska A
FEBS Open Bio 14 (10) 1656-1667 [2024-10-00; online 2024-06-04]
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Sex bias in FGFR3 somatic mutations in bladder cancer
Meng X, Wang Q
Oncol Transl Med 10 (5) 252-256 [2024-10-00; online 2024-08-12]
DDLS Fellow Qiaoli Wang
PubMed DOI Crossref
Proteomic changes in Alzheimer's disease associated with progressive Aβ plaque and tau tangle pathologies.
Pichet Binette A, Gaiteri C, Wennström M, ..., Vogel JW, Hansson O
Nat. Neurosci. 27 (10) 1880-1891 [2024-10-00; online 2024-08-26]
DDLS Fellow Jacob W Vogel
PubMed DOI Crossref
Production of stable and pure ZC3H11A - An extensively disordered RNA binding protein.
Fekry M, Stenberg G, Dobritzsch D, Danielson UH
Protein Expr. Purif. 222 (-) 106542 [2024-10-00; online 2024-07-04]
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PDGF-induced internalisation promotes proteolytic cleavage of PDGFRβ in mesenchymal cells.
Rubin Sander M, Tsiatsiou AK, Wang K, ..., Heldin CH, Lennartsson J
Growth Factors 42 (4) 147-160 [2024-10-00; online 2024-10-10]
PubMed DOI Crossref
Multiplex plasma protein assays as a diagnostic tool for lung cancer.
Ahamed MT, Forshed J, Levitsky A, ..., Eriksson LE, Andersson B
Cancer Sci. 115 (10) 3439-3454 [2024-10-00; online 2024-07-30]
PubMed DOI Crossref
Lipidome changes due to improved dietary fat quality inform cardiometabolic risk reduction and precision nutrition.
Eichelmann F, Prada M, Sellem L, ..., Schulze MB, Wittenbecher C
Nat. Med. 30 (10) 2867-2877 [2024-10-00; online 2024-07-11]
Clemens Wittenbecher DDLS Fellow
PubMed DOI Crossref
Leveraging zebrafish to investigate pancreatic development, regeneration, and diabetes.
Mi J, Ren L, Andersson O
Trends in molecular medicine 30 (10) 932-949 [2024-10-00; online 2024-06-01]
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LD-transpeptidation is crucial for fitness and polar growth in Agrobacterium tumefaciens.
Aliashkevich A, Guest T, Alvarez L, ..., Brown PJB, Cava F
PLoS Genet 20 (10) e1011449 [2024-10-00; online 2024-10-21]
PubMed DOI Crossref
Kinetic and structural characterization of NUDT15 and NUDT18 as catalysts of isoprene pyrophosphate hydrolysis.
Scaletti ER, Unterlass JE, Almlöf I, ..., Stenmark P, Jemth AS
FEBS J. 291 (19) 4301-4322 [2024-10-00; online 2024-06-29]
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Iron deficiency in new onset heart failure: association with clinical factors and quality of life.
Cabrera CC, Ekström M, Tornvall P, ..., Persson B, Lyngå P
ESC Heart Fail 11 (5) 2661-2671 [2024-10-00; online 2024-05-27]
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Genetic Stock Identification Reveals Mismatches Between Management Areas and Population Genetic Structure in a Migratory Pelagic Fish.
Seljestad GW, Quintela M, Bekkevold D, ..., Glover KA, Berg F
Evol Appl 17 (10) e70030 [2024-10-00; online 2024-10-24]
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Generation of a ZEB2 deficient human iPSC line (KICRi002A-4).
Schuster J, Fatima A, Papadopoulos N, ..., Sobol M, Dahl N
Stem Cell Res 80 (-) 103521 [2024-10-00; online 2024-07-31]
PubMed DOI Crossref
Emerging methods and applications in 3D genomics.
Pedrotti S, Castiglioni I, Perez-Estrada C, ..., Crosetto N, Bienko M
Curr Opin Cell Biol 90 (-) 102409 [2024-10-00; online 2024-08-22]
PubMed DOI Crossref
Design and evaluation of novel inhibitors for the treatment of clear cell renal cell carcinoma.
Bouzian Y, El Hafi M, Parvizi N, ..., Turkez H, Mardinoglu A
Bioorg Chem 151 (-) 107597 [2024-10-00; online 2024-07-06]
PubMed DOI Crossref
Blood lipid profiling indicates that dietary fat quality is associated with cardiometabolic risk.
Nat. Med. 30 (10) 2735-2736 [2024-10-00; online 2024-08-31]
Clemens Wittenbecher DDLS Fellow
PubMed DOI Crossref
Beyond basic characterization and omics: Immunomodulatory roles of platelet-derived extracellular vesicles unveiled by functional testing.
Palviainen M, Puutio J, Østergaard RH, ..., Hayashi Y, Siljander PR
J Extracell Vesicles 13 (10) e12513 [2024-10-00; online 2024-09-27]
PubMed DOI Crossref
Bayesian polynomial neural networks and polynomial neural ordinary differential equations.
Fronk C, Yun J, Singh P, Petzold L
PLoS Comput Biol 20 (10) e1012414 [2024-10-00; online 2024-10-10]
Prashant Singh SciLifeLab Fellow
PubMed DOI Crossref
Author Correction: Immune system adaptation during gender-affirming testosterone treatment.
Lakshmikanth T, Consiglio C, Sardh F, ..., Landegren N, Brodin P
Nature 634 (8033) E5 [2024-10-00; online 2024-09-25]
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Assessment of the exposure to cytotoxic Bacillus cereus group genotypes through high-temperature, short-time milk consumption.
Su J, Chandross-Cohen T, Qian C, ..., Wiedmann M, Kovac J
J Dairy Sci 107 (10) 7631-7647 [2024-10-00; online 2024-06-06]
DDLS Fellow Laura Carroll
PubMed DOI Crossref
A virally encoded tRNA neutralizes the PARIS antiviral defence system.
Burman N, Belukhina S, Depardieu F, ..., Wiedenheft B, Isaev A
Nature 634 (8033) 424-431 [2024-10-00; online 2024-08-07]
PubMed DOI Crossref
A versatile tissue-rolling technique for spatial-omics analyses of the entire murine gastrointestinal tract.
Monasterio G, Morales RA, Bejarano DA, ..., Das S, Villablanca EJ
Nat Protoc 19 (10) 3085-3137 [2024-10-00; online 2024-06-21]
PubMed DOI Crossref
A cocktail of histidine, carnosine, cysteine and serine reduces adiposity and improves metabolic health and adipose tissue immunometabolic function in ovariectomized rats.
Baudin J, Hernandez-Baixauli J, Romero-Giménez J, ..., Arola L, Caimari A
Biomed. Pharmacother. 179 (-) 117326 [2024-10-00; online 2024-08-28]
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376 (PB364): Targeting TGF-β signaling components to ameliorate Palbociclib resistance in breast cancer
Ali M, Itoh Y, Heldin CH, Moustakas A
Eur. J. Cancer 211 (-) 114889 [2024-10-00; online 2024-10-00]
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MirGeneDB 3.0: Improved taxonomic sampling, uniform nomenclature of novel conserved microRNA families, and updated covariance models
Clarke AW, Høye E, Hembrom AA, ..., Peterson KJ, Fromm B
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The regulatory landscape of interacting RNA and protein pools in cellular homeostasis and cancer.
Gallardo-Dodd CJ, Kutter C
Hum Genomics 18 (1) 109 [2024-09-27; online 2024-09-27]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Syngap1 Promotes Cognitive Function through Regulation of Cortical Sensorimotor Dynamics.
Vaissiere T, Michaelson SD, Creson T, ..., Fontolan L, Rumbaugh G
bioRxiv - (-) - [2024-09-27; online 2024-09-27]
PubMed DOI Crossref
SpLitteR: diploid genome assembly using TELL-Seq linked-reads and assembly graphs.
Tolstoganov I, Chen Z, Pevzner P, Korobeynikov A
PeerJ 12 (-) e18050 [2024-09-27; online 2024-09-27]
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Introducing synthetic thermostable RNase inhibitors to single-cell RNA-seq.
Noble JC, Lentini A, Hagemann-Jensen M, Sandberg R, Reinius B
Nat Commun 15 (1) 8373 [2024-09-27; online 2024-09-27]
Antonio Lentini DDLS Fellow
PubMed DOI Crossref
Antimicrobial Dihydroflavonols and Isoflavans Isolated from the Root Bark of Dalbergia gloveri.
Kiganda I, Wieske LHE, Nchiozem-Ngnitedem VA, ..., Yenesew A, Erdelyi M
J Nat Prod 87 (9) 2263-2271 [2024-09-27; online 2024-09-10]
Ruisheng Xiong SciLifeLab Fellow
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Targeting mutant p53: Evaluation of novel anti-p53 R175H monoclonal antibodies as diagnostic tools
Spiegelberg D, Hwang LA, Pua KH, ..., Nestor M, Lane DP
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Discovery of 2-Aryl-4-aminoquinazolin-Based LSD1 Inhibitors to Activate Immune Response in Gastric Cancer.
Wang B, Wang SW, Zhou Y, ..., Chen XB, Dai XJ
J Med Chem 67 (18) 16165-16184 [2024-09-26; online 2024-09-12]
PubMed DOI Crossref
Single-cell dissection of the human blood-brain barrier and glioma blood-tumor barrier.
Xie Y, Yang F, He L, ..., Wang L, Zhang L
Neuron 112 (18) 3089-3105.e7 [2024-09-25; online 2024-08-26]
PubMed DOI Crossref
Gastrin-releasing peptide receptor as theranostic target in estrogen-receptor positive breast cancer: A preclinical study of the theranostic pair [55Co]Co- and [177Lu]Lu-DOTA-RM26.
Baun C, Olsen BB, Alves CML, ..., Dam JH, Thisgaard H
Nucl. Med. Biol. 138-139 (-) 108961 [2024-09-25; online 2024-09-25]
PubMed DOI Crossref
Enhancing T-cell recruitment in renal cell carcinoma with cytokine-armed adenoviruses.
Feodoroff M, Hamdan F, Antignani G, ..., Grönholm M, Cerullo V
Oncoimmunology 13 (1) 2407532 [2024-09-25; online 2024-09-25]
PubMed DOI Crossref
A resource of identified and annotated lincRNAs expressed during somatic embryogenesis development in Norway spruce.
Canovi C, Stojkovič K, Benítez AA, ..., Egertsdotter U, Street NR
Physiol Plant 176 (5) e14537 [2024-09-25; online 2024-09-25]
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The Organelle in the Ointment: improved detection of cryptic mitochondrial reads resolves many unknown sequences in cross-species microbiome analyses
Sonett D, Brown T, Bengtsson-Palme J, Padilla-Gamiño JL, Zaneveld JR
ISME Commun - (-) - [2024-09-24; online 2024-09-24]
DDLS Fellow Johan Bengtsson-Palme
DOI Crossref
Longitudinal analysis of genetic and environmental interplay in human metabolic profiles and the implication for metabolic health
Wang J, Zenere A, Wang X, ..., Uhlén M, Zhong W
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PubMed DOI Crossref
Making PBPK models more reproducible in practice.
Domínguez-Romero E, Mazurenko S, Scheringer M, ..., Županič A, Suarez-Diez M
Brief. Bioinformatics 25 (6) - [2024-09-23; online 2024-11-04]
PubMed DOI Crossref
Improved sub-genomic RNA prediction with the ARTIC protocol.
Baudeau T, Sahlin K
Nucleic Acids Res. 52 (17) e82 [2024-09-23; online 2024-08-16]
Kristoffer Sahlin SciLifeLab Fellow
PubMed DOI Crossref
A machine learning-based prediction of tau load and distribution in Alzheimer's disease using plasma, MRI and clinical variables.
Karlsson L, Vogel J, Arvidsson I, ..., Mattsson-Carlgren N, Hansson O
medRxiv - (-) - [2024-09-23; online 2024-09-23]
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Microgravity Effect on Pancreatic Islets.
Zeger L, Barasa P, Han Y, ..., Christoffersson G, Kozlova EN
Cells 13 (18) - [2024-09-21; online 2024-09-21]
Gustaf Christoffersson SciLifeLab Fellow
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FunCoup 6: advancing functional association networks across species with directed links and improved user experience
Buzzao D, Persson E, Guala D, Sonnhammer ELL
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Biodiversity of microorganisms in the Baltic Sea: the power of novel methods in the identification of marine microbes.
Mazur-Marzec H, Andersson AF, Błaszczyk A, ..., Witkowski A, Węgrzyn A
FEMS Microbiol Rev 48 (5) - [2024-09-18; online 2024-10-06]
PubMed DOI Crossref
Integrating amyloid and tau imaging with proteomics and genomics in Alzheimer's disease.
Vilkaite G, Vogel J, Mattsson-Carlgren N
Cell Rep Med 5 (9) 101735 [2024-09-17; online 2024-09-19]
DDLS Fellow Jacob W Vogel
PubMed DOI Crossref
Contextualising samples: supporting reference genomes of European biodiversity through sample and associated metadata collection.
Böhne A, Fernández R, Leonard JA, ..., Vinnere Pettersson O, Struck TH
NPJ Biodivers 3 (1) 26 [2024-09-17; online 2024-09-17]
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Conserved Evolutionary Response to Whole Genome Duplication in Angiosperms Revealed Using High Resolution Gene Expression Profiling
Leal JL, Hodková E, Billhardt A, ..., Salojärvi J, Lascoux M
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BCL2 expression is enriched in advanced prostate cancer with features of lineage plasticity.
Westaby D, Jiménez-Vacas JM, Figueiredo I, ..., de Bono J, Sharp A
J. Clin. Invest. 134 (18) - [2024-09-17; online 2024-09-17]
Arian Lundberg DDLS Fellow
PubMed DOI Crossref
Aurora B and Aurora C pools at two chromosomal regions collaboratively maintain chromosome alignment and prevent aneuploidy at the second meiotic division in mammalian oocytes.
Kouznetsova A, Valentiniene S, Liu JG, ..., Brismar H, Höög C
Front Cell Dev Biol 12 (-) 1470981 [2024-09-17; online 2024-09-17]
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An Atlas of Accessible Chromatin in Advanced Prostate Cancer Reveals the Epigenetic Evolution during Tumor Progression.
Shrestha R, Chesner LN, Zhang M, ..., Quigley DA, Feng FY
Cancer Res. 84 (18) 3086-3100 [2024-09-16; online 2024-07-11]
Arian Lundberg DDLS Fellow
PubMed DOI Crossref
Maternal pre-pregnancy BMI influences the associations between bisphenol and phthalate exposures and maternal weight changes and fat accumulation.
Irvine N, Bell RC, Subhan FB, ..., England-Mason G, APrON Study Team
Environ. Res. 257 (-) 119276 [2024-09-15; online 2024-06-01]
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The CHCHD2-CHCHD10 protein complex is modulated by mitochondrial dysfunction and alters lipid homeostasis in the mouse brain
Gerlach J, Pireddu P, Zhang X, ..., Svenningsson P, Filograna R
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Sequence variants influencing the regulation of serum IgG subclass levels.
Olafsdottir TA, Thorleifsson G, Lopez de Lapuente Portilla A, ..., Nilsson B, Stefansson K
Nat Commun 15 (1) 8054 [2024-09-14; online 2024-09-14]
Abhishek Niroula DDLS Fellow
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Nasal transcriptomic profiling reveals distinct patterns in Type 2 Asthma
Merid SK, Hernandez-Pacheco N, Björkander S, ..., Koppelman GH, Melén E
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Cigarette smoking, but not snuff usage, is associated with a systemic inflammatory profile in young adults
Björkander S, Klevebro S, Hernandez-Pacheco N, ..., Bergström A, Melén E
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Biomarkers in ICU-treated Covid-19 patients 4 and 10 months after discharge: evidence for persistent inflammation and remodeling
Kalafatis D, Björnson M, Kistner A, ..., Westergren-Thorsson G, Sköld M
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Microbial dietary preference and interactions affect the export of lipids to the deep ocean.
Behrendt L, Alcolombri U, Hunter JE, ..., Stocker R, Van Mooy BAS
Science (New York, N.Y.) 385 (6714) eaab2661 [2024-09-13; online 2024-09-13]
Lars Behrendt SciLifeLab Fellow
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Discovery of a 6-Aminobenzo[b]thiophene 1,1-Dioxide Derivative (K2071) with a Signal Transducer and Activator of Transcription 3 Inhibitory, Antimitotic, and Senotherapeutic Activities.
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Barbotin A, Billaudeau C, Sezgin E, Carballido-López R
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Dev. Cell 59 (16) 2189-2202.e8 [2024-08-19; online 2024-07-31]
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Koukaroudi D, Qiu Z, Fransén E, ..., Seibt J, Grant SGN
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Hugerth LW, Krog MC, Vomstein K, ..., Nielsen HS, Schuppe-Koistinen I
Microbiome 12 (1) 153 [2024-08-19; online 2024-08-19]
DDLS Fellow Luisa Hugerth
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Nat Commun 15 (1) 7111 [2024-08-19; online 2024-08-19]
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Curti L, Rohban S, Bianchi N, ..., Parazzoli D, Campaner S
Nat Commun 15 (1) 7100 [2024-08-18; online 2024-08-18]
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Lee H, Langseth CM, Salas SM, ..., Grillo M, Nilsson M
Development 151 (16) - [2024-08-15; online 2024-08-29]
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Nilsson M, Kozyrev SV, Lindblad-Toh K, Rönnberg H, Hansson-Hamlin H
Acta Vet Scand 66 (1) 39 [2024-08-15; online 2024-08-15]
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Erb IK, Suarez C, Frank EM, ..., Lindberg E, Paul CJ
FEMS Microbes 5 (-) xtae024 [2024-08-14; online 2024-08-14]
DDLS Fellow Johan Bengtsson-Palme
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Distinct bacterial and protist plankton diversity dynamics uncovered through DNA-based monitoring in the Baltic Sea area
Jurdzinski KT, Latz MA, Torstensson A, ..., Karlson B, Andersson AF
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Sun W-S, Torrens G, Ter Beek J, Cava F, Berntsson RP-A
MBio 15 (8) e0048824 [2024-08-14; online 2024-06-28]
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Eriksen R, White MC, Dawed AY, ..., Frost G, Pearson ER
J. Clin. Endocrinol. Metab. 109 (9) e1697-e1707 [2024-08-13; online 2024-04-30]
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Genomic and transcriptomic features of androgen receptor signaling inhibitor resistance in metastatic castration-resistant prostate cancer.
Zhu X, Farsh T, Vis D, ..., van der Heijden MS, Feng FY
J. Clin. Invest. 134 (19) - [2024-08-13; online 2024-08-13]
Arian Lundberg DDLS Fellow
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Four decades of research on Viktor Mutt’s neuropeptides with focus on galanin
Hökfelt T, Barde S, Zhong W, Xu ZQD, Alberts P
PEAS 73 (3) 170-192 [2024-08-12; online 2024-08-12]
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A role for the S4-domain containing protein YlmH in ribosome-associated quality control in Bacillus subtilis.
Takada H, Paternoga H, Fujiwara K, ..., Wilson DN, Hauryliuk V
Nucleic Acids Res. 52 (14) 8483-8499 [2024-08-12; online 2024-05-30]
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Sex-Specific Associations between Prenatal Exposure to Bisphenols and Phthalates and Infant Epigenetic Age Acceleration.
England-Mason G, Merrill SM, Liu J, ..., Kobor MS, Dewey D
Epigenomes 8 (3) - [2024-08-10; online 2024-08-10]
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Duplexed CeTEAM drug biosensors reveal determinants of PARP inhibitor selectivity
Pires MJ, Lovric A, Alam S, ..., Altun M, Valerie NCK
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Pathway activation model for personalized prediction of drug synergy
Trac QT, Huang Y, Erkers T, ..., Pawitan Y, Vu TN
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Stimulated emission depletion microscopy
Lukinavičius G, Alvelid J, Gerasimaitė R, ..., Han KY, Testa I
Nat Rev Methods Primers 4 (1) - [2024-08-08; online 2024-08-08]
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Insights into the mechanisms driven by H3K4 KMTs in pancreatic cancer.
LaRue-Nolan KC, Raja Arul GL, Sigafoos AN, Shi J, Fernandez-Zapico ME
Biochem. J. 481 (15) 983-997 [2024-08-07; online 2024-07-30]
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Hypoxic-Ischemic Insult Alters Polyamine and Neurotransmitter Abundance in the Specific Neonatal Rat Brain Subregions.
Mácha H, Luptáková D, Juránek I, Andrén PE, Havlíček V
ACS Chem Neurosci 15 (15) 2811-2821 [2024-08-07; online 2024-07-26]
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Extensively acquired antimicrobial resistant bacteria restructure the individual microbial community in post-antibiotic conditions
Baek JW, Lim S, Park N, ..., Koh A, Lee S
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Association of polygenic scores for autism with volumetric MRI phenotypes in cerebellum and brainstem in adults.
Mohammad S, Gentreau M, Dubol M, ..., Mwinyi J, Schiöth HB
Mol Autism 15 (1) 34 [2024-08-07; online 2024-08-07]
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Applying Spatial Metabolomics To Investigate Age- and Drug-Induced Neurochemical Changes.
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β-Carboline-based light and pH dual stimuli-responsive ion transporters induce cancer cell death.
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Hydrogen production by a fully de novo enzyme.
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Integrating Natural and Engineered Genetic Variation to Decode Regulatory Influence on Blood Traits
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Deciphering the genetics and mechanisms of predisposition to multiple myeloma.
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Abhishek Niroula DDLS Fellow
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Understanding the interplay between dNTP metabolism and genome stability in cancer.
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Effects of oral contraceptives and menopausal hormone therapy on the risk of rheumatoid arthritis: a prospective cohort study.
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The brittle star genome illuminates the genetic basis of animal appendage regeneration.
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Structure-based virtual screening of vast chemical space as a starting point for drug discovery.
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SMYD5 methylation of rpL40 links ribosomal output to gastric cancer.
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Role of estrogen signaling in fibroblastic reticular cells for innate and adaptive immune responses in antigen-induced arthritis.
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Mechanistic screening of reproductive toxicity in a novel 3D testicular co-culture model shows significant impairments following exposure to low-dibutyl phthalate concentrations.
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Maternal exposure to bisphenols, phthalates, perfluoroalkyl acids, and trace elements and their associations with gestational diabetes mellitus in the APrON cohort.
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Mapping the Multiscale Proteomic Organization of Cellular and Disease Phenotypes.
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Mapping spatially resolved transcriptomes in human and mouse pulmonary fibrosis.
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Maculopathy and adult-onset ataxia in patients with biallelic MFSD8 variants.
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Mol Genet Genomic Med 12 (8) e2505 [2024-08-00; online 2024-08-07]
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Integrated analyses highlight interactions between the three-dimensional genome and DNA, RNA and epigenomic alterations in metastatic prostate cancer.
Zhao SG, Bootsma M, Zhou S, ..., Lupien M, Feng FY
Nat. Genet. 56 (8) 1689-1700 [2024-08-00; online 2024-07-17]
Arian Lundberg DDLS Fellow
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Genotyping oral contraceptive users for venous thromboembolism risk.
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Exploring Paleogene Tibet's warm temperate environments through target enrichment and phylogenetic niche modelling of Himalayan spiny frogs (Paini, Dicroglossidae).
Hofmann S, Rödder D, Andermann T, ..., Schmidt J, Podsiadlowski L
Mol. Ecol. 33 (15) e17446 [2024-08-00; online 2024-07-01]
DDLS Fellow Tobias Andermann
PubMed DOI Crossref
Epidemiological and environmental investigation of the 'big four' Vibrio species, 1994 to 2021: a Baltic Sea retrospective study.
Gyraitė G, Kataržytė M, Bučas M, ..., Lastauskienė E, Labrenz M
Euro Surveill 29 (32) - [2024-08-00; online 2024-08-09]
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Direct presentation of inflammation-associated self-antigens by thymic innate-like T cells induces elimination of autoreactive CD8+ thymocytes.
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Development and implementation of assays to monitor human adenovirus F40/41 in wastewater: Trends preceding, during, and following the non-A-to-E hepatitis outbreak in Stockholm.
Perez-Zabaleta M, Williams C, Cetecioglu Z
Environ Int 190 (-) 108937 [2024-08-00; online 2024-08-05]
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Combining VPS34 inhibitors with STING agonists enhances type I interferon signaling and anti-tumor efficacy.
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Mol Oncol 18 (8) 1904-1922 [2024-08-00; online 2024-03-20]
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BioImage.IO Chatbot: a community-driven AI assistant for integrative computational bioimaging.
Lei W, Fuster-Barceló C, Reder G, Muñoz-Barrutia A, Ouyang W
Nat. Methods 21 (8) 1368-1370 [2024-08-00; online 2024-08-10]
DDLS Fellow Wei Ouyang
PubMed DOI Crossref
Artificial intelligence for high content imaging in drug discovery.
Carreras-Puigvert J, Spjuth O
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A suicidal and extensively disordered luciferase with a bright luminescence.
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Protein Sci. 33 (8) e5115 [2024-08-00; online 2024-07-18]
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A second space age spanning omics, platforms and medicine across orbits.
Mason CE, Green J, Adamopoulos KI, ..., Mateus J, Beheshti A
Nature 632 (8027) 995-1008 [2024-08-00; online 2024-06-11]
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A Visual Environment for Data Driven Protein Modeling and Validation.
Falk M, Tobiasson V, Bock A, Hansen C, Ynnerman A
IEEE Trans Vis Comput Graph 30 (8) 5063-5073 [2024-08-00; online 2024-07-01]
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Inhibition of IRAP Enhance the Expression of Pro-cognitive Markers Drebrin and MAP2 in Rat Primary Neuronal Cells
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Bacteria combine polar- and dispersed-growth to power cell elongation and wall width dynamics
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Genome-wide expression analysis in a Fabry disease human podocyte cell line.
Snanoudj S, Derambure C, Zhang C, ..., Bekri S, Tebani A
Heliyon 10 (14) e34357 [2024-07-30; online 2024-07-09]
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Cryo-EM structures of ρ1 GABA A receptors with antagonist and agonist drugs
Fan C, Cowgill J, Howard RJ, Lindahl E
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Helical superstructures between amyloid and collagen in cardiac fibrils from a patient with AL amyloidosis.
Schulte T, Chaves-Sanjuan A, Speranzini V, ..., Palladini G, Ricagno S
Nat Commun 15 (1) 6359 [2024-07-28; online 2024-07-28]
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Selective lysis of acute myeloid leukemia cells by CD34/CD3 bispecific antibody through the activation of γδ T-cells.
Al Agrafi F, Gaballa A, Hahn P, ..., Uhlin M, Stikvoort A
Oncoimmunology 13 (1) 2379063 [2024-07-27; online 2024-07-27]
PubMed DOI Crossref
OCT1 (SLC22A1) transporter kinetics and regulation in primary human hepatocyte 3D spheroids.
Mickols E, Meyer A, Handin N, ..., Karlgren M, Artursson P
Sci Rep 14 (1) 17334 [2024-07-27; online 2024-07-27]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Large-scale proteomics reveals precise biomarkers for detection of ovarian cancer in symptomatic women.
Ivansson E, Hedlund Lindberg J, Stålberg K, ..., Gyllensten U, Enroth S
Sci Rep 14 (1) 17288 [2024-07-27; online 2024-07-27]
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Disparate and shared transcriptomic signatures associated with cortical atrophy in genetic bvFTD.
Shen T, Vogel JW, Van Deerlin VM, ..., Irwin DJ, McMillan CT
medRxiv - (-) - [2024-07-27; online 2024-07-27]
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Complex Polyploids: Origins, Genomic Composition, and Role of Introgressed Alleles.
Leal JL, Milesi P, Hodková E, ..., Salojärvi J, Lascoux M
Syst. Biol. 73 (2) 392-418 [2024-07-27; online 2024-04-13]
DDLS Fellow Jennifer James Pascal Milesi SciLifeLab Fellow
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Autoantibodies towards HFE and SYT5 in anti-neutrophil cytoplasm antibody-associated vasculitis relapse
Bayati S, Nazeer J, Ng J, ..., Nilsson P, Pin E
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Adaptive Robust Learning using Latent Bernoulli Variables
Karakulev A, Zachariah D, Singh P
Proceedings of the 41st International Conference on Machine Learning, PMLR 235 (-) 23105-23122 [2024-07-27; online 2023-12-04]
Prashant Singh SciLifeLab Fellow
PubMed DOI Crossref
Loss of the tumour suppressor LKB1/STK11 uncovers a leptin-mediated sensitivity mechanism to mitochondrial uncouplers for targeted cancer therapy.
Angelopoulou A, Theocharous G, Valakos D, ..., Papaspyropoulos A, Gorgoulis VG
Mol Cancer 23 (1) 147 [2024-07-25; online 2024-07-25]
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Improved protein complex prediction with AlphaFold-multimer by denoising the MSA profile
Bryant P, Noé F
PLoS Comput Biol 20 (7) e1012253 [2024-07-25; online 2024-07-25]
DDLS Fellow Patrick Bryant
DOI Crossref
Distinct Plasma Protein Profiles Distinguish Faster from Slower Disease Progression in HIV-1 and HIV-2 infections
Johansson E, Nazziwa J, Freyhult E, ..., Jansson M, Esbjörnsson J
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MpANT regulates meristem development in Marchantia polymorpha.
Liu W, Yang Z, Cai G, ..., Willemsen V, Xu L
Cell Reports 43 (7) 114466 [2024-07-23; online 2024-07-09]
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High-Resolution Mass Spectrometry for Human Exposomics: Expanding Chemical Space Coverage.
Lai Y, Koelmel JP, Walker DI, ..., Jones DP, Miller GW
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Protective alleles and precision healthcare in crewed spaceflight.
Rutter LA, MacKay MJ, Cope H, ..., Giacomello S, Mason CE
Nat Commun 15 (1) 6158 [2024-07-22; online 2024-07-22]
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Glutamine-addiction in cisplatin resistant cancer cells is mediated by SLC7A11 and can be targeted with asparaginase therapy
Wang J, Strauss R, Bartek J, Rudd SG
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Discovery of Cell-Permeable Allosteric Inhibitors of Liver Pyruvate Kinase: Design and Synthesis of Sulfone-Based Urolithins.
Iqbal S, Islam MZ, Ashraf S, ..., Turkez H, Mardinoglu A
Int J Mol Sci 25 (14) - [2024-07-22; online 2024-07-22]
PubMed DOI Crossref
Multiscale photocatalytic proximity labeling reveals cell surface neighbors on and between cells.
Lin Z, Schaefer K, Lui I, ..., Sali A, Wells JA
Science (New York, N.Y.) 385 (6706) eadl5763 [2024-07-19; online 2024-07-19]
Andrea Fossati DDLS Fellow
PubMed DOI Crossref
Discovery of a Therapeutic Agent for Glioblastoma Using a Systems Biology-Based Drug Repositioning Approach.
Kaynar A, Ozcan M, Li X, ..., Shoaie S, Mardinoglu A
Int J Mol Sci 25 (14) - [2024-07-18; online 2024-07-18]
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Electromigrated Gold Nanogap Tunnel Junction Arrays: Fabrication and Electrical Behavior in Liquid and Gaseous Media.
Raja SN, Jain S, Kipen J, ..., Herland A, Niklaus F
ACS Appl Mater Interfaces 16 (28) 37131-37146 [2024-07-17; online 2024-07-02]
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A potential space-making role in cell wall biogenesis for SltB1and DacB revealed by a beta-lactamase induction phenotype in Pseudomonas aeruginosa.
Gyger J, Torrens G, Cava F, Bernhardt TG, Fumeaux C
MBio 15 (7) e0141924 [2024-07-17; online 2024-06-26]
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Waves of transcription drive erythroid differentiation and launch the NRF2-activated antioxidant program
Karppi I, Pessa JC, Rabenius A, ..., Sistonen L, Vihervaara A
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Mapping the contribution of the C-linker domain to gating polarity in CNBD channels.
Lin JL, Chang Y, Tewari D, Cowgill J, Chanda B
Biophys. J. 123 (14) 2176-2184 [2024-07-16; online 2024-04-27]
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Divergent evolution of male-determining loci on proto-Y chromosomes of the housefly.
Li X, Visser S, Son JH, ..., Bopp D, Beukeboom LW
Nat Commun 15 (1) 5984 [2024-07-16; online 2024-07-16]
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Ancient tree-topologies and gene-flow processes among human lineages in Africa
Breton G, Sjödin P, Zervakis PI, ..., Jakobsson M, Verdu P
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An intracellular hydrophobic nexus critical for hERG1 channel slow deactivation.
Stevens-Sostre WA, Flores-Aldama L, Bustos D, ..., Delemotte L, Robertson GA
Biophys. J. 123 (14) 2024-2037 [2024-07-16; online 2024-01-12]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
TMEM16F scramblase regulates angiogenesis via endothelial intracellular signaling.
Shan KZ, Le T, Liang P, ..., Claesson-Welsh L, Yang H
J. Cell. Sci. 137 (14) - [2024-07-15; online 2024-07-18]
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Retraction notice to "Combined metabolic activators improve metabolic functions in the animal models of neurodegenerative diseases" [Life Sci. 314 (2023) 121325].
Turkez H, Altay O, Yildirim S, ..., Uhlén M, Mardinoglu A
Life Sci 349 (-) 122712 [2024-07-15; online 2024-05-18]
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Discovery and in vitro Evaluation of Novel Serotonin 5-HT2A Receptor Ligands Identified Through Virtual Screening.
Zięba A, Bartuzi D, Stępnicki P, ..., Castro M, Kaczor AA
ChemMedChem 19 (14) e202400080 [2024-07-15; online 2024-05-29]
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Advances in development of biomarkers for brain damage and ischemia.
Karimova D, Rostami E, Chubarev VN, ..., Schiöth HB, Rask-Andersen M
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SignalP: The Evolution of a Web Server.
Nielsen H, Teufel F, Brunak S, von Heijne G
Methods in molecular biology (Clifton, N.J.) 2836 (-) 331-367 [2024-07-12; online 2024-07-12]
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How sex and gender shape functional brain networks.
Matte Bon G, Kraft D, Kaufmann T
Sci Adv 10 (28) eadq3079 [2024-07-12; online 2024-07-12]
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Cardiomyocyte antisense transcription regulates exon usage in the elastic spring region of Titin to modulate sarcomere function
Celik S, Hyrefelt L, Czuba T, ..., Smith JG, Gidlöf O
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Nasal tissue-resident memory CD4 + T cells persist after influenza A virus infection and provide heterosubtypic protection
Mathew NR, Gailleton R, Scharf L, ..., Tang KW, Angeletti D
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Mechanism of phage sensing and restriction by toxin-antitoxin-chaperone systems.
Mets T, Kurata T, Ernits K, ..., Atkinson GC, Hauryliuk V
Cell Host Microbe 32 (7) 1059-1073.e8 [2024-07-10; online 2024-05-30]
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Evolutionary rescue of spherical mreB deletion mutants of the rod-shape bacterium Pseudomonas fluorescens SBW25
Yulo PRJ, Desprat N, Gerth ML, ..., Rainey PB, Hendrickson HL
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Characterization of a lipid-based jumbo phage compartment as a hub for early phage infection.
Mozumdar D, Fossati A, Stevenson E, ..., Swaney DL, Bondy-Denomy J
Cell Host Microbe 32 (7) 1050-1058.e7 [2024-07-10; online 2024-06-12]
Andrea Fossati DDLS Fellow
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Cerebrospinal fluid levels of NfM in relation to NfL and pNfH as prognostic markers in amyotrophic lateral sclerosis
Olofsson J, Bergström S, Mravinacová S, ..., Nilsson P, Månberg A
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Associations between Microglia and Astrocytic Proteins and Tau Biomarkers across the Continuum of Alzheimer's Disease.
Doroszkiewicz J, Kulczyńska-Przybik A, Dulewicz M, ..., Blennow K, Mroczko B
Int J Mol Sci 25 (14) - [2024-07-09; online 2024-07-09]
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Advancing drug discovery through assay development: a survey of tool compounds within the human solute carrier superfamily.
Digles D, Ingles-Prieto A, Dvorak V, ..., Wiedmer T, Superti-Furga G
Front. Pharmacol. 15 (-) 1401599 [2024-07-09; online 2024-07-09]
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Simulating the Skin Permeation Process of Ionizable Molecules.
Lundborg M, Wennberg C, Lindahl E, Norlén L
J Chem Inf Model 64 (13) 5295-5302 [2024-07-08; online 2024-06-25]
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Genome-scale metabolic network of human carotid plaque reveals the pivotal role of glutamine/glutamate metabolism in macrophage modulating plaque inflammation and vulnerability.
Jin H, Zhang C, Nagenborg J, ..., Mardinoglu A, Biessen EAL
Cardiovasc Diabetol 23 (1) 240 [2024-07-08; online 2024-07-08]
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Broadcasters, receivers, functional groups of metabolites, and the link to heart failure by revealing metabolomic network connectivity.
Yazdani A, Mendez-Giraldez R, Yazdani A, ..., Larson MG, Elsea SH
Metabolomics 20 (4) 71 [2024-07-07; online 2024-07-07]
Clemens Wittenbecher DDLS Fellow
DOI Crossref
Cellular and molecular events organizing the assembly of tertiary lymphoid structures in glioblastoma
Vaccaro A, Yang F, van de Walle T, ..., Ramachandran M, Dimberg A
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ADAR-Mediated A>I(G) RNA Editing in the Genotoxic Drug Response of Breast Cancer.
Bernal YA, Durán E, Solar I, Sagredo EA, Armisén R
Int J Mol Sci 25 (13) - [2024-07-06; online 2024-07-06]
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Nucleotide binding to the ATP-cone in anaerobic ribonucleotide reductases allosterically regulates activity by modulating substrate binding.
Bimai O, Banerjee I, Rozman Grinberg I, ..., Sjöberg BM, Logan DT
Elife 12 (-) - [2024-07-05; online 2024-07-05]
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A generalizable data-driven model of atrophy heterogeneity and progression in memory clinic settings.
Baumeister H, Vogel JW, Insel PS, ..., Hansson O, Berron D
Brain 147 (7) 2400-2413 [2024-07-05; online 2024-04-24]
DDLS Fellow Jacob W Vogel
PubMed DOI Crossref
Rapid genome sequencing for critically ill infants: an inaugural pilot study from Turkey.
Guner Yilmaz B, Akgun-Dogan O, Ozdemir O, ..., Ozbek U, Alanay Y
Front Pediatr 12 (-) 1412880 [2024-07-04; online 2024-07-04]
PubMed DOI Crossref
A single-cell transcriptomic study of heterogeneity in human embryonic tanycytes.
Bai Y, Chen Q, Li Y
Sci Rep 14 (1) 15384 [2024-07-04; online 2024-07-04]
PubMed DOI Crossref
Historic dog Furs Unravel the Origin and Artificial Selection of Modern Nordic Lapphund and Elkhound dog Breeds.
Wang SZ, Yan Y, Widlund M, ..., Savolainen P, Wang GD
Mol. Biol. Evol. 41 (7) - [2024-07-03; online 2024-06-06]
PubMed DOI Crossref
High Caveolin-1 mRNA expression in triple-negative breast cancer is associated with an aggressive tumor microenvironment, chemoresistance, and poor clinical outcome.
Godina C, Khazaei S, Belting M, ..., Bosch A, Jernström H
PLoS ONE 19 (7) e0305222 [2024-07-03; online 2024-07-03]
PubMed DOI Crossref
Flotillin-mediated stabilization of unfolded proteins in bacterial membrane microdomains.
Ukleja M, Kricks L, Torrens G, ..., Cava F, Lopez D
Nat Commun 15 (1) 5583 [2024-07-03; online 2024-07-03]
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Investigations of microbiota composition and neuroactive pathways in association with symptoms of stress and depression in a cohort of healthy women.
Bashir Z, Hugerth LW, Krog MC, ..., Fransson E, Nielsen HS
Front. Cell. Infect. Microbiol. 14 (-) 1324794 [2024-07-02; online 2024-07-02]
DDLS Fellow Luisa Hugerth
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Vaginal Microbiota Transplantation (VMT) for treatment of vaginal dysbiosis without the use of antibiotics – A Double-Blinded Randomized Controlled Trial in healthy women with vaginal dysbiosis
Wrønding T, Vomstein K, DeLong K, ..., Ensign LM, Nielsen HS
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MDverse: Shedding Light on the Dark Matter of Molecular Dynamics Simulations
Tiemann JKS, Szczuka M, Bouarroudj L, ..., Chavent M, Poulain P
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High-bandwidth low-current measurement system for automated and scalable probing of tunnel junctions in liquids.
Raja SN, Jain S, Kipen J, ..., Herland A, Niklaus F
Rev Sci Instrum 95 (7) - [2024-07-01; online 2024-07-22]
PubMed DOI Crossref
Deletion of CD44 promotes adipogenesis by regulating PPARγ and cell cycle-related pathways.
Weng X, Jiang H, Walker DJ, ..., Wang J, Kang L
J Endocrinol 262 (1) - [2024-07-01; online 2024-05-20]
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Cancer Core Europe: Leveraging Institutional Synergies to Advance Oncology Research and Care Globally.
Carmona J, Chavarria E, Donoghue K, ..., Zwart W, Tabernero J
Cancer Discov 14 (7) 1147-1153 [2024-07-01; online 2024-06-13]
PubMed DOI Crossref
CCG-1423-derived compounds reduce global RNA synthesis and inhibit transcriptional responses.
Prajapati B, Sokolova M, Sidorenko E, ..., Vihervaara A, Vartiainen MK
J. Cell. Sci. 137 (13) - [2024-07-01; online 2024-07-15]
Anniina Vihervaara SciLifeLab Fellow
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Author response: MDverse: Shedding Light on the Dark Matter of Molecular Dynamics Simulations
Tiemann JKS, Szczuka M, Bouarroudj L, ..., Chavent M, Poulain P
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Special issue: TGF-β and epithelial-mesenchymal transition in cancer.
Ten Dijke P, Miyazono K, Heldin CH, Moustakas A
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Novel drug targets and molecular mechanisms for sarcopenia based on systems biology.
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Lipid imaging of Alzheimer's disease pathology.
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Zhang M, Sjöström M, Cui X, ..., Feng FY, Quigley DA
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Arian Lundberg DDLS Fellow
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Identification of Gene‐Therapy Responsive Blood Biomarkers in mdx Mouse Model
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Exploring BPA alternatives - Environmental levels and toxicity review.
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Lars Behrendt SciLifeLab Fellow
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Evaluation of activated sludge settling characteristics from microscopy images with deep convolutional neural networks and transfer learning
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Gisele Miranda SciLifeLab Fellow
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Enhancing Neuronal Cell Uptake of Therapeutic Nucleic Acids with Tetrahedral DNA Nanostructures.
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Small 20 (29) e2309140 [2024-07-00; online 2024-02-11]
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Enhanced Cellular Uptake through Nanotopography‐Induced Macropinocytosis
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Engineering of Saccharomyces cerevisiae for enhanced metabolic robustness and L-lactic acid production from lignocellulosic biomass.
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Effects and avoidance of photoconversion-induced artifacts in confocal and STED microscopy.
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Detection and quantification of Na,K-ATPase dimers in the plasma membrane of living cells by FRET-FCS.
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Corrigendum to "Discovery of therapeutic agents targeting PKLR for NAFLD using drug repositioning" [eBioMedicine, 2022;83:104214].
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EBioMedicine 105 (-) 105224 [2024-07-00; online 2024-06-28]
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Comparison of Xrn1 and Rat1 5' → 3' exoribonucleases in budding yeast supports the specific role of Xrn1 in cotranslational mRNA decay.
Pérez-Ortín JE, Jordán-Pla A, Zhang Y, ..., Pelechano V, García-Martínez J
Yeast 41 (7) 458-472 [2024-07-00; online 2024-06-14]
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Cleanroom-Free Direct Laser Micropatterning of Polymers for Organic Electrochemical Transistors in Logic Circuits and Glucose Biosensors.
Enrico A, Buchmann S, De Ferrari F, ..., Herland A, Zeglio E
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Cactus: A user-friendly and reproducible ATAC-Seq and mRNA-Seq analysis pipeline for data preprocessing, differential analysis, and enrichment analysis.
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Being Breastfed in Infancy and Risk of Colorectal Cancer and Precursor Lesions.
Yuan C, Wang QL, Kim H, ..., Giovannucci EL, Ng K
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The quantification of zebrafish ocular-associated proteins provides hints for sex-biased visual impairments and perception.
Niksirat H, Siino V, Steinbach C, Levander F
Heliyon 10 (12) e33057 [2024-06-30; online 2024-06-13]
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Population History and Admixture of the Fulani People from the Sahel
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CPSign: conformal prediction for cheminformatics modeling.
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Implementing AI in Advanced Recycling of Perovskite Solar Cells
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Elasto-inertial focusing and particle migration in high aspect ratio microchannels for high-throughput separation.
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Decrypting lysine deacetylase inhibitor action and protein modifications by dose-resolved proteomics.
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Design of linear and cyclic peptide binders of different lengths from protein sequence information
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Mass Spectrometry Proteomics Characterization of Plasma Biomarkers for Colorectal Cancer Associated With Inflammation.
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Host-bacteria interactions: ecological and evolutionary insights from ancient, professional endosymbionts.
Bontemps Z, Paranjape K, Guy L
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Hidden secrets of the cancer genome: unlocking the impact of non-coding mutations in gene regulatory elements.
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Identification of fragments targeting SMYD3 using highly sensitive kinetic and multiplexed biosensor-based screening.
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RSC Med Chem 15 (6) 1982-1990 [2024-06-19; online 2024-03-20]
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Discovery of tumour indicating morphological changes in benign prostate biopsies through AI
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SURG-02. INTRAOPERATIVE APPLICATION OF A POLYMER-BASED HYDROGEL AGAINST MEDULLOBLASTOMA GROUP 3 AND ATYPICAL TERATOID/RHABDOID TUMOURS
Moloney C, ElSherbeny A, McCrorie P, ..., Smith SJ, Rahman R
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Deciphering the functional specialization of whole-brain spatiomolecular gradients in the adult brain.
Vogel JW, Alexander-Bloch AF, Wagstyl K, ..., Satterthwaite TD, Seidlitz J
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DDLS Fellow Jacob W Vogel
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DIPG-27. MATCHED PRIMARY-RELAPSE PEDHGG PATIENT-DERIVED XENOGRAFT MODELS TO IDENTIFY THERAPY RESISTANCE PROFILES
Barnerjee S, Zhao M, Rosen G, ..., Holmberg KO, Giraud G
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Disease progression modelling reveals heterogeneity in trajectories of Lewy-type α-synuclein pathology.
Mastenbroek SE, Vogel JW, Collij LE, ..., Beach TG, Hansson O
Nat Commun 15 (1) 5133 [2024-06-15; online 2024-06-15]
DDLS Fellow Jacob W Vogel
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Cortical morphology variations during the menstrual cycle in individuals with and without premenstrual dysphoric disorder.
Dubol M, Stiernman L, Sundström-Poromaa I, Bixo M, Comasco E
J Affect Disord 355 (-) 470-477 [2024-06-15; online 2024-03-27]
Erika Comasco SciLifeLab Fellow
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Wide-scale Geographical Analysis of Genetic Ancestry in the South African Coloured Population
Lankheet I, Hammarén R, Caballero LXA, ..., de Jongh M, Schlebusch C
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Human In Vitro Models of Neuroenergetics and Neurometabolic Disturbances: Current Advances and Clinical Perspectives.
Rogal J, Zamproni LN, Nikolakopoulou P, ..., Wredenberg A, Herland A
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Author response: Activity modulation in anaerobic ribonucleotide reductases: nucleotide binding to the ATP-cone allosterically mediates substrate binding to the active site
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Activity modulation in anaerobic ribonucleotide reductases: nucleotide binding to the ATP-cone allosterically mediates substrate binding to the active site
Bimaï O, Banerjee I, Grinberg IR, ..., Sjöberg BM, Logan DT
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Novel Dihydropteridinone Derivatives As Potent Inhibitors of the Understudied Human Kinases Vaccinia-Related Kinase 1 and Casein Kinase 1δ/ε.
de Souza Gama FH, Dutra LA, Hawgood M, ..., Azevedo H, Couñago RM
J Med Chem 67 (11) 8609-8629 [2024-06-13; online 2024-05-23]
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Exploring penetrance of clinically relevant variants in over 800,000 humans from the Genome Aggregation Database.
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SETD8 inhibition targets cancer cells with increased rates of ribosome biogenesis
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Construction of the ETECFinder database for the characterization of enterotoxigenic Escherichia coli (ETEC) and revision of the VirulenceFinder web tool at the CGE website.
Scheutz F, Nielsen CH, von Mentzer A
J. Clin. Microbiol. 62 (6) e0057023 [2024-06-12; online 2024-04-24]
Astrid von Mentzer DDLS Fellow
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Pharmaceutical Quality by Design Approach to Develop High-Performance Nanoparticles for Magnetic Hyperthermia.
Ansari SR, Suárez-López YDC, Thersleff T, ..., Rinaldi-Ramos CM, Teleki A
ACS Nano 18 (23) 15284-15302 [2024-06-11; online 2024-05-30]
Alexandra Teleki SciLifeLab Fellow
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Hemangiosarcoma Cells Promote Conserved Host-derived Hematopoietic Expansion.
Kim JH, Schulte AJ, Sarver AL, ..., Kaufman DS, Modiano JF
Cancer Res Commun 4 (6) 1467-1480 [2024-06-11; online 2024-05-17]
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EchoGrid: High-Throughput Acoustic Trapping for Enrichment of Environmental Microplastics.
Costa M, Hammarström B, van der Geer L, ..., Wiklund M, Russom A
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Astronaut omics and the impact of space on the human body at scale.
Rutter LA, Cope H, MacKay MJ, ..., Mason CE, Giacomello S
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Aquaporin-4 as an early cerebrospinal fluid biomarker of Alzheimer’s disease
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The Effect of Metformin Treatment on the Circulating Proteome
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Pathway activation model for personalized prediction of drug synergy
Trac QT, Huang Y, Erkers T, ..., Pawitan Y, Vu TN
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Improved Detection of Drug-Induced Liver Injury by Integrating Predicted in vivo and in vitro Data.
Seal S, Williams DP, Hosseini-Gerami L, ..., Spjuth O, Bender A
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Fluoroquinolone-Specific Resistance Trajectories in E. coli and their Dependence on the SOS-Response
Teichmann L, Luitwieler S, Bengtsson-Palme J, ter Kuile B
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Aβ Oligomer Dissociation Is Catalyzed by Fibril Surfaces.
Dear AJ, Thacker D, Wennmalm S, ..., Linse S, Knowles TPJ
ACS Chem Neurosci 15 (11) 2296-2307 [2024-06-05; online 2024-05-24]
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Author Correction: Gene-expression memory-based prediction of cell lineages from scRNA-seq datasets.
Eisele AS, Tarbier M, Dormann AA, Pelechano V, Suter DM
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The N-terminal SAM domain of the dNTPase SAMHD1 is not required for inhibition by small molecule TH6342.
Dirks C, Bwanika HC, Jemth AS, Zhang SM, Rudd SG
Nucleosides Nucleotides Nucleic Acids 43 (8) 831-836 [2024-06-03; online 2024-06-03]
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MoLPC2: improved prediction of large protein complex structures and stoichiometry using Monte Carlo Tree Search and AlphaFold2.
Chim HY, Elofsson A
Bioinformatics 40 (6) - [2024-06-03; online 2024-05-23]
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Experimental validation of numerical point spread function calculation including aberration estimation.
Holinirina Dina Miora R, Senftleben M, Abrahamsson S, ..., Heintzmann R, Bosman G
Opt Express 32 (12) 21887-21908 [2024-06-03; online 2024-06-11]
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Chemical signatures delineate heterogeneous amyloid plaque populations across the Alzheimer's disease spectrum.
Koutarapu S, Ge J, Dulewicz M, ..., Schöll M, Hanrieder J
bioRxiv - (-) - [2024-06-03; online 2024-06-03]
SciLifeLab Fellow Wojciech Michno
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Chemical Exposomics in Human Plasma by Lipid Removal and Large Volume Injection Gas Chromatography High-Resolution Mass Spectrometry
Xie H, Sdougkou K, Papazian S, ..., Rantakokko P, Martin J
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Virtual special issue of Nordic POP: Patient-oriented products.
Rosenholm JM, Flaten GE, Teleki A
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Atrial Fibrillation and Clonal Hematopoiesis in TET2 and ASXL1.
Saadatagah S, Naderian M, Uddin M, ..., Kullo IJ, Ballantyne CM
JAMA Cardiol 9 (6) 497-506 [2024-06-01; online 2024-04-10]
Abhishek Niroula DDLS Fellow
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The use of systems biology in treatment of metabolic diseases
Mardinoglu A
Free Radic. Biol. Med. 218 (-) 53 [2024-06-00; online 2024-06-00]
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The nexus of nuclear envelope dynamics, circular economy and cancer cell pathophysiology.
Keuper K, Bartek J, Maya-Mendoza A
Eur J Cell Biol 103 (2) 151394 [2024-06-00; online 2024-02-06]
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Temperature and water availability drive insect seasonality across a temperate and a tropical region.
van Dijk LJA, Fisher BL, Miraldo A, ..., Roslin T, Tack AJM
Proc. Biol. Sci. 291 (2025) 20240090 [2024-06-00; online 2024-06-19]
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Structure of plant photosystem I in a native assembly state defines PsaF as a regulatory checkpoint.
Naschberger A, Fadeeva M, Klaiman D, ..., Nelson N, Amunts A
Nat Plants 10 (6) 874-879 [2024-06-00; online 2024-05-30]
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Structural dynamics of therapeutic nucleic acids with phosphorothioate backbone modifications.
Carlesso A, Hörberg J, Deganutti G, Reymer A, Matsson P
NAR Genomics and Bioinformatics 6 (2) lqae058 [2024-06-00; online 2024-05-25]
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Plasma bile acids in association with Crohn's disease.
Kiasat A, Prast-Nielsen S, Rautiainen S, ..., Löf Granström A, Gustafsson UO
Scand. J. Gastroenterol. 59 (6) 674-682 [2024-06-00; online 2024-03-20]
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Peripheral Blood Mononuclear Cell Gene Expression Associated with Pulmonary Microvascular Perfusion: The Multi-Ethnic Study of Atherosclerosis Chronic Obstructive Pulmonary Disease.
Buschur KL, Pottinger TD, Vogel-Claussen J, ..., Lappalainen T, Barr RG
Ann Am Thorac Soc 21 (6) 884-894 [2024-06-00; online 2024-02-09]
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OP0179 DISEASE ASSOCIATED AUTOANTIBODIES ARE LINKED TO GRADUAL PROTEOMIC CHANGES IN PRIMARY SJÖGREN’S SYNDROME
Björk A, Mofors J, Meneghel L, ..., Nordmark G, Wahren-Herlenius M
Ann Rheum Dis 83 (-) 42-43 [2024-06-00; online 2024-06-00]
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OP0139 THE MOLECULAR LANDSCAPE OF ANTIPHOSPHOLIPID SYNDROME IN SYSTEMIC LUPUS ERYTHEMATOSUS: DISTINCT TRANSCRIPTIONAL PROFILES IN VENOUS VERSUS ARTERIAL EVENTS, WITH POTENTIAL THERAPEUTIC IMPLICATIONS
Nikolopoulos D, Loukogiannaki C, Sentis G, ..., Filia A, Boumpas D
Ann Rheum Dis 83 (-) 23-24 [2024-06-00; online 2024-06-00]
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Mixing Insulating Commodity Polymers with Semiconducting n-type Polymers Enables High-Performance Electrochemical Transistors.
Zeglio E, Wang Y, Jain S, ..., Hamedi MM, Herland A
Adv. Mater. Weinheim 36 (23) e2302624 [2024-06-00; online 2024-03-10]
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Mid-pregnancy allopregnanolone levels and trajectories of perinatal depressive symptoms.
Björväng RD, Walldén Y, Fransson E, ..., Sundström-Poromaa I, Skalkidou A
Psychoneuroendocrinology 164 (-) 107009 [2024-06-00; online 2024-02-28]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Malat1 affects transcription and splicing through distinct pathways in mouse embryonic stem cells.
Aslanzadeh M, Stanicek L, Tarbier M, ..., Biryukova I, Friedländer MR
NAR Genomics and Bioinformatics 6 (2) lqae045 [2024-06-00; online 2024-05-06]
DDLS Fellow Marcel Tarbier
PubMed DOI Crossref
Macrophages upregulate mural cell-like markers and support healing of ischemic injury by adopting functions important for vascular support.
Amoedo-Leite C, Parv K, Testini C, ..., Christoffersson G, Phillipson M
Nat Cardiovasc Res 3 (6) 685-700 [2024-06-00; online 2024-06-06]
Gustaf Christoffersson SciLifeLab Fellow
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Live-cell imaging powered by computation.
Shroff H, Testa I, Jug F, Manley S
Nat. Rev. Mol. Cell Biol. 25 (6) 443-463 [2024-06-00; online 2024-02-20]
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How ancient RNA survives and what we can learn from it.
Friedländer MR, Gilbert MTP
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High-throughput molecular assays for inclusion in personalised oncology trials - State-of-the-art and beyond.
Edsjö A, Russnes HG, Lehtiö J, ..., Rosenquist R, PCM4EU consortium
J. Intern. Med. 295 (6) 785-803 [2024-06-00; online 2024-05-02]
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Genomic landscapes of divergence among island bird populations: Evidence of parallel adaptation but at different loci?
Martin CA, Sheppard EC, Ali HAA, ..., Spurgin LG, Richardson DS
Mol. Ecol. 33 (12) e17365 [2024-06-00; online 2024-05-11]
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Genomic basis of the distinct biosynthesis of β-glucogallin, a biochemical marker for hydrolyzable tannin production, in three oak species.
Yang Q, Li J, Wang Y, ..., Liu Y, Li G
New Phytol. 242 (6) 2702-2718 [2024-06-00; online 2024-03-21]
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Functional and structural insights into activation of TRPV2 by weak acids.
Haug FM, Pumroy RA, Sridhar A, ..., Moiseenkova-Bell V, Leffler A
EMBO J. 43 (11) 2264-2290 [2024-06-00; online 2024-04-26]
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Effects of small-scale outplanting fertilization on conifer seedling growth and fungal community establishment
Schneider AN, Castro D, Holmlund M, ..., Hurry V, Street NR
Trees, Forests and People 16 (-) 100568 [2024-06-00; online 2024-06-00]
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Effects of boric acid on volatile tellurium in severe accident conditions
Börjesson Sandén F, Pasi AE, Kärkelä T, Kajolinna T, Ekberg C
Annals of Nuclear Energy 200 (-) 110412 [2024-06-00; online 2024-06-00]
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Design and synthesis of novel JNK inhibitors targeting liver pyruvate kinase for the treatment of non-alcoholic fatty liver disease and hepatocellular carcinoma
Iqbal S, Sebhaoui J, Ashraf S, ..., Turkez H, Mardinoglu A
Bioorganic Chemistry 147 (-) 107425 [2024-06-00; online 2024-06-00]
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DL4MicEverywhere: deep learning for microscopy made flexible, shareable and reproducible.
Hidalgo-Cenalmor I, Pylvänäinen JW, G Ferreira M, ..., Henriques R, Gómez-de-Mariscal E
Nat. Methods 21 (6) 925-927 [2024-06-00; online 2024-05-18]
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Comment to: "SCA4 Unravelled After More than 25 Years Using Advanced Genomic Technologies".
Paucar M, Nilsson D, Engvall M, ..., Wedell A, Svenningsson P
Mov Disord 39 (6) 1077 [2024-06-00; online 2024-06-26]
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Cellular responses to silencing of PDIA3 (protein disulphide-isomerase A3): Effects on proliferation, migration, and genes in control of active vitamin D.
Kermpatsou D, Olsson F, Wåhlén E, ..., Lennartsson J, Norlin M
J. Steroid Biochem. Mol. Biol. 240 (-) 106497 [2024-06-00; online 2024-03-07]
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The ABCF ATPase New1 resolves translation termination defects associated with specific tRNAArg and tRNALys isoacceptors in the P site.
Turnbull K, Paternoga H, von der Weth E, ..., Wilson DN, Hauryliuk V
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Cotranslational membrane insertion of the voltage-sensitive K + channel KvAP
Westerfield JM, Kozojedová P, Juli C, Metola A, von Heijne G
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Structure prediction of protein-ligand complexes from sequence information with Umol
Bryant P, Kelkar A, Guljas A, Clementi C, Noé F
Nat Commun 15 (1) - [2024-05-28; online 2024-05-28]
DDLS Fellow Patrick Bryant
PubMed DOI Crossref
Bacillamide D produced by Bacillus cereus from the mouse intestinal bacterial collection (miBC) is a potent cytotoxin in vitro.
Hohmann M, Brunner V, Johannes W, ..., Janßen KP, Gulder TAM
Commun Biol 7 (1) 655 [2024-05-28; online 2024-05-28]
DDLS Fellow Laura Carroll
PubMed DOI Crossref
An Automated Versatile Diagnostic Workflow for Infectious Disease Detection in Low-Resource Settings.
Urrutia Iturritza M, Mlotshwa P, Gantelius J, ..., Jönsson HN, Gaudenzi G
Micromachines (Basel) 15 (6) - [2024-05-28; online 2024-05-28]
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2-Aryladenine Derivatives as a Potent Scaffold for Adenosine Receptor Antagonists: The 6-Morpholino Derivatives.
Areias F, Correia C, Rocha A, ..., Proença MF, Carvalho MA
Molecules 29 (11) - [2024-05-28; online 2024-05-28]
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Synthesis and Biological Evaluation of Novel Benzylidene Thiazolo Pyrimidin-3(5 )-One Derivatives
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Daniel Globisch SciLifeLab Fellow
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Eur Urol Oncol - (-) - [2024-05-23; online 2024-05-23]
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Diagnosis of Cancer After Recent Weight Loss-Reply.
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JAMA 331 (19) 1678-1679 [2024-05-21; online 2024-04-24]
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Mitoribosome structure with cofactors and modifications reveals mechanism of ligand binding and interactions with L1 stalk.
Singh V, Itoh Y, Del'Olio S, ..., Taoka M, Amunts A
Nat Commun 15 (1) 4272 [2024-05-20; online 2024-05-20]
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Non-invasive PET imaging of liver fibrogenesis using a RESCA-conjugated Affibody molecule.
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An atlas of protein-protein associations of human tissues prioritizes candidate disease genes
Laman Trip DS, van Oostrum M, Memon D, ..., Wollscheid B, Beltrao P
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Andrea Fossati DDLS Fellow
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The full spectrum of SLC22 OCT1 mutations illuminates the bridge between drug transporter biophysics and pharmacogenomics.
Yee SW, Macdonald CB, Mitrovic D, ..., Giacomini KM, Coyote-Maestas W
Mol. Cell 84 (10) 1932-1947.e10 [2024-05-16; online 2024-05-03]
Lucie Delemotte SciLifeLab Fellow
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Microfluidic Cartridge for Bead-Based Affinity Assays.
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Compositional and functional differences of the vaginal microbiota of women with and without cervical dysplasia.
Norenhag J, Edfeldt G, Stålberg K, ..., Schuppe-Koistinen I, Olovsson M
Sci Rep 14 (1) 11183 [2024-05-16; online 2024-05-16]
DDLS Fellow Luisa Hugerth
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Matte Bon G, Kraft D, Comasco E, Derntl B, Kaufmann T
Biol Sex Differ 15 (1) 42 [2024-05-15; online 2024-05-15]
Erika Comasco SciLifeLab Fellow
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Clear effects on root system architecture of winter wheat cultivars (Triticum aestivum L.) from cultivation environment and practices.
Cope JE, Berckx F, Lundmark J, ..., Karlsson I, Weih M
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Spatial Coherence in DNA Barcode Networks
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Nucleobase catalysts for the enzymatic activation of 8-oxoguanine DNA glycosylase 1
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Iron oxide nanoparticles for treatment and diagnosis of chronic inflammatory diseases: A systematic review.
Ansari SR, Mahajan J, Teleki A
Wiley Interdiscip Rev Nanomed Nanobiotechnol 16 (3) e1963 [2024-05-10; online 2024-05-10]
Alexandra Teleki SciLifeLab Fellow
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TPP1 is associated with risk of advanced precursors and cervical cancer survival.
Wang QL, Gong C, Meng XY, ..., Wu Q, Zhou Y
PLoS ONE 19 (5) e0298118 [2024-05-09; online 2024-05-09]
DDLS Fellow Qiaoli Wang
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Chromatin damage generated by DNA intercalators leads to degradation of RNA Polymerase II.
Espinoza JA, Kanellis DC, Saproo S, ..., Bartek J, Lindström MS
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A Decade in a Systematic Review: The Evolution and Impact of Cell Painting.
Seal S, Trapotsi MA, Spjuth O, ..., Bender A, Carpenter AE
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High Resolution Crystal Structure of the Pyruvate Kinase Tetramer in Complex with the Allosteric Activator Mitapivat/AG-348
Han X, Sandalova T, Zhang C, ..., Achour A, Sun R
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GROMACS on AMD GPU-Based HPC Platforms: Using SYCL for Performance and Portability
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Adaptive sampling-based structural prediction reveals opening of a GABA receptor through the αβ interface
Haloi N, Howard RJ, Lindahl E
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MDverse: Shedding Light on the Dark Matter of Molecular Dynamics Simulations.
Tiemann JKS, Szczuka M, Bouarroudj L, ..., Chavent M, Poulain P
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Differential expression of plasma proteins in pregnant women exposed to Plasmodium falciparum malaria
Kanoi BN, Waweru H, Kobia FM, ..., Gitaka J, Kamali-Moghaddam M
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Geiser P, Martino MLD, Lopes ACC, ..., Eriksson J, Sellin ME
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Ancestral terpene cyclases: From fundamental science to applications in biosynthesis.
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Spatial transcriptomics Visium data for mouse bleomycin model of lung fibrosis
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Evolutionary convergence of sensory circuits in the pallium of amniotes
Rueda-Alaña E, Senovilla-Ganzo R, Grillo M, ..., De Pitta M, García-Moreno F
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CopyVAE: a variational autoencoder-based approach for copy number variation inference using single-cell transcriptomics.
Kurt S, Chen M, Toosi H, ..., Hartman J, Lagergren J
Bioinformatics 40 (5) - [2024-05-02; online 2024-04-28]
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Abstract PO3-25-07: Characterization of tertiary lymphoid structures and its association with response to immune checkpoint inhibitors in triple negative breast cancer using spatial transcriptomics
Wang X, Venet D, Lifrange F, ..., Rothé F, Sotiriou C
Cancer Res. 84 (9_Supplement) PO3-25-07-PO3-25-07 [2024-05-02; online 2024-05-02]
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Cerebrospinal fluid reference proteins increase accuracy and interpretability of biomarkers for brain diseases.
Karlsson L, Vogel J, Arvidsson I, ..., Mattsson-Carlgren N, Hansson O
Nat Commun 15 (1) 3676 [2024-05-01; online 2024-05-01]
DDLS Fellow Jacob W Vogel
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Olesinski EA, Bhatia KS, Wang C, ..., Letai A, Bhatt S
Blood Cancer Discov 5 (3) 180-201 [2024-05-01; online 2024-03-05]
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White matter volume and treatment with selective progesterone receptor modulator in patients with premenstrual dysphoric disorder.
Kaltsouni E, Wikström J, Lanzenberger R, Sundström-Poromaa I, Comasco E
Psychoneuroendocrinology 163 (-) 106977 [2024-05-00; online 2024-01-22]
Erika Comasco SciLifeLab Fellow
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The decanoate esters of nandrolone, testosterone, and trenbolone induce steroid specific memory impairment and somatic effects in the male rat.
Zelleroth S, Stam F, Nylander E, ..., Grönbladh A, Hallberg M
Horm Behav 161 (-) 105501 [2024-05-00; online 2024-02-17]
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Super-sectioning with multi-sheet reversible saturable optical fluorescence transitions (RESOLFT) microscopy.
Bodén A, Ollech D, York AG, Millett-Sikking A, Testa I
Nat. Methods 21 (5) 882-888 [2024-05-00; online 2024-02-23]
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Scuphr: A probabilistic framework for cell lineage tree reconstruction.
Koptagel H, Jun SH, Hård J, Lagergren J
PLoS Comput Biol 20 (5) e1012094 [2024-05-00; online 2024-05-09]
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Brismar H, Senftleben M, Latron E, ..., Edwards S, Ogazon A
Physiology 39 (S1) - [2024-05-00; online 2024-05-00]
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Genomic basis of seed colour in quinoa inferred from variant patterns using extreme gradient boosting.
Sandell FL, Holzweber T, Street NR, Dohm JC, Himmelbauer H
Plant Biotechnol J 22 (5) 1312-1324 [2024-05-00; online 2024-01-11]
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Keaton JM, Kamali Z, Xie T, ..., Snieder H, Warren HR
Nat. Genet. 56 (5) 778-791 [2024-05-00; online 2024-04-30]
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Generation of Anterior Segment of the Eye Cells from hiPSCs in Microfluidic Platforms.
Koçak G, Uyulgan S, Polatlı E, ..., Utine CA, Güven S
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Vujasinovic M, Elbe P, Ekheden I, ..., Löhr JM, Ludvigsson JF
Scand. J. Gastroenterol. 59 (5) 600-607 [2024-05-00; online 2024-02-13]
DDLS Fellow Qiaoli Wang
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Disease staging of Alzheimer's disease using a CSF-based biomarker model.
Salvadó G, Horie K, Barthélemy NR, ..., Bateman RJ, Hansson O
Nat Aging 4 (5) 694-708 [2024-05-00; online 2024-03-21]
DDLS Fellow Jacob W Vogel
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Colonization factors of human and animal-specific enterotoxigenic Escherichia coli (ETEC).
von Mentzer A, Svennerholm AM
Trends Microbiol. 32 (5) 448-464 [2024-05-00; online 2023-12-04]
Astrid von Mentzer DDLS Fellow
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Cellular energy regulates mRNA degradation in a codon-specific manner.
Tomaz da Silva P, Zhang Y, Theodorakis E, ..., Pelechano V, Gagneur J
Mol Syst Biol 20 (5) 506-520 [2024-05-00; online 2024-03-15]
SciLifeLab Fellow Vicent Pelechano
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COVID-19 vaccine uptake among young adults: Influence of asthma and sociodemographic factors.
Ödling M, Andersson N, Ekström S, ..., Melén E, Kull I
J Allergy Clin Immunol Glob 3 (2) 100231 [2024-05-00; online 2024-02-20]
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Shrine N, Guyatt AL, Erzurumluoglu AM, ..., Tobin MD, Wain LV
Nat. Genet. 56 (5) 1032-1033 [2024-05-00; online 2024-04-20]
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Arachidonic acid and docosahexaenoic acid levels correlate with the inflammation proteome in extremely preterm infants.
Klevebro S, Kebede Merid S, Sjöbom U, ..., Hellström A, Nilsson AK
Clin Nutr 43 (5) 1162-1170 [2024-05-00; online 2024-04-03]
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MassiveFold: unveiling AlphaFold’s hidden potential with optimized and parallelized massive sampling
Raouraoua N, Mirabello C, Véry T, ..., Lensink M, Brysbaert G
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Drivers Underlying Metastasis and Relapse in Medulloblastoma and Targeting Strategies.
Holmberg KO, Borgenvik A, Zhao M, Giraud G, Swartling FJ
Cancers (Basel) 16 (9) - [2024-04-30; online 2024-04-30]
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Clonal Hematopoiesis of Indeterminate Potential With Loss of Tet2 Enhances Risk for Atrial Fibrillation Through Nlrp3 Inflammasome Activation.
Lin AE, Bapat AC, Xiao L, ..., Ellinor PT, Ebert BL
Circulation 149 (18) 1419-1434 [2024-04-30; online 2024-02-15]
Abhishek Niroula DDLS Fellow
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Mapping Lesions that Cause Psychosis to a Human Brain Circuit and Proposed Stimulation Target
Pines AR, Frandsen SB, Drew W, ..., Silbersweig D, Siddiqi SH
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Loss of NEDD8 in cancer cells causes vulnerability to immune checkpoint blockade in triple-negative breast cancer.
Papakyriacou I, Kutkaite G, Rúbies Bedós M, ..., Menden MP, Mao Y
Nat Commun 15 (1) 3581 [2024-04-27; online 2024-04-27]
SciLifeLab Fellow Yumeng Mao
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Tissue and cellular spatiotemporal dynamics in colon aging.
Daly AC, Cambuli F, Äijö T, ..., Regev A, Vickovic S
bioRxiv - (-) - [2024-04-26; online 2024-04-26]
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New approach methods to assess developmental and adult neurotoxicity for regulatory use: a PARC work package 5 project.
Tal T, Myhre O, Fritsche E, ..., Torres-Ruiz M, Bartmann K
Front Toxicol 6 (-) 1359507 [2024-04-26; online 2024-04-26]
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Interpreting mammalian evolutionary constraint at synonymous sites in light of the unwanted transcript hypothesis
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Deep learning insights into the architecture of the mammalian egg-sperm fusion synapse.
Elofsson A, Han L, Bianchi E, Wright GJ, Jovine L
Elife 13 (-) - [2024-04-26; online 2024-04-26]
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Deep learning insights into the architecture of the mammalian egg-sperm fusion synapse
Elofsson A, Han L, Bianchi E, Wright GJ, Jovine L
Elife 13 (-) - [2024-04-26; online 2024-04-26]
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Loss of Y in regulatory T lymphocytes in the tumor micro-environment of primary colorectal cancers and liver metastases.
Wójcik M, Juhas U, Mohammadi E, ..., Filipowicz N, Dumanski JP
Sci Rep 14 (1) 9458 [2024-04-24; online 2024-04-24]
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Inhibitors of dermatan sulfate epimerase 1 decreased accumulation of glycosaminoglycans in mucopolysaccharidosis type I fibroblasts.
Maccarana M, Li B, Li H, ..., Yu M, Li JP
Glycobiology 34 (6) - [2024-04-24; online 2024-05-18]
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Cell Painting-based bioactivity prediction boosts high-throughput screening hit-rates and compound diversity.
Fredin Haslum J, Lardeau CH, Karlsson J, ..., Smith K, Müllers E
Nat Commun 15 (1) 3470 [2024-04-24; online 2024-04-24]
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Two Novel [68Ga]Ga-Labeled Radiotracers Based on Metabolically Stable [Sar11]RM26 Antagonistic Peptide for Diagnostic Positron Emission Tomography Imaging of GRPR-Positive Prostate Cancer.
Kanellopoulos P, Bezverkhniaia E, Abouzayed A, ..., Tolmachev V, Orlova A
ACS Omega 9 (16) 18608-18616 [2024-04-23; online 2024-04-10]
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Author Correction: scCircle-seq unveils the diversity and complexity of extrachromosomal circular DNAs in single cells.
Chen JP, Diekmann C, Wu H, ..., Bienko M, Crosetto N
Nat Commun 15 (1) 3390 [2024-04-22; online 2024-04-22]
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Patient-Specific Measurable Residual Disease Markers Predict Outcome in Patients With Myelodysplastic Syndrome and Related Diseases After Hematopoietic Stem-Cell Transplantation.
Tobiasson M, Pandzic T, Illman J, ..., Dybedal I, Hellström-Lindberg E
J Clin Oncol 42 (12) 1378-1390 [2024-04-20; online 2024-01-17]
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Inference of drug off-target effects on cellular signaling using interactome-based deep learning.
Meimetis N, Lauffenburger DA, Nilsson A
iScience 27 (4) 109509 [2024-04-19; online 2024-03-14]
Avlant Nilsson DDLS Fellow
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Divergent mechanisms of steroid inhibition in the human ρ1 GABAA receptor
Lindahl E, Fan C, Cowgill J, Howard R
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PubMed DOI Crossref
Nucleolar stress caused by arginine-rich peptides triggers a ribosomopathy and accelerates aging in mice.
Sirozh O, Saez-Mas A, Jung B, ..., Lafarga V, Fernandez-Capetillo O
Mol. Cell 84 (8) 1527-1540.e7 [2024-04-18; online 2024-03-22]
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Longitudinal Exposomics in a Multiomic Wellness Cohort Reveals Distinctive and Dynamic Environmental Chemical Mixtures in Blood
Sdougkou K, Papazian S, Bonnefille B, ..., Martin LJ, Martin JW
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PubMed DOI Crossref
Comparison of the performance of multiple whole-genome sequence-based tools for the identification of Bacillus cereus sensu stricto biovar Thuringiensis.
Chung T, Salazar A, Harm G, ..., Carroll LM, Kovac J
Applied and environmental microbiology 90 (4) e0177823 [2024-04-17; online 2024-03-12]
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Microenvironmental reorganization in brain tumors following radiotherapy and recurrence revealed by hyperplexed immunofluorescence imaging.
Watson SS, Duc B, Kang Z, ..., Hausser J, Joyce JA
Nat Commun 15 (1) 3226 [2024-04-15; online 2024-04-15]
PubMed DOI Crossref
Efficient calculation of orientation-dependent lipid dynamics from membrane simulations.
Doktorova M, Khelashvili G, Brown MF
bioRxiv - (-) - [2024-04-15; online 2024-04-15]
DDLS Fellow Milka Doktorova
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Macromolecular condensation organizes nucleolar sub-phases to set up a pH gradient.
King MR, Ruff KM, Lin AZ, ..., Vahey MD, Pappu RV
Cell 187 (8) 1889-1906.e24 [2024-04-11; online 2024-03-18]
PubMed DOI Crossref
Recalibrating differential gene expression by genetic dosage variance prioritizes functionally relevant genes.
Rentzsch P, Kollotzek A, Mohammadi P, Lappalainen T
bioRxiv - (-) - [2024-04-10; online 2024-04-10]
PubMed DOI Crossref
Paternal leakage of plastids rescues inter-lineage hybrids in Silene nutans.
Postel Z, Van Rossum F, Godé C, Schmitt E, Touzet P
Ann. Bot. 133 (3) 427-434 [2024-04-10; online 2023-12-23]
DOI Crossref
Deep learning insights into the architecture of the mammalian egg-sperm fusion synapse
Elofsson A, Han L, Bianchi E, Wright GJ, Jovine L
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DOI Crossref
Author response: Deep learning insights into the architecture of the mammalian egg-sperm fusion synapse
Elofsson A, Han L, Bianchi E, Wright GJ, Jovine L
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Multiple pro-viral effects of the host protein G3BP in SARS-CoV-2 Infection
McInerney G, Long S, Vidakovics LP, ..., Guzyk M, Coquet J
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GRPR-Antagonists Carrying DOTAGA-Chelator via Positively Charged Linkers: Perspectives for Prostate Cancer Theranostics.
Obeid K, Kanellopoulos P, Abouzayed A, ..., Maina T, Orlova A
Pharmaceutics 16 (4) - [2024-04-08; online 2024-04-08]
PubMed DOI Crossref
Drug repositioning for immunotherapy in breast cancer using single-cell analysis.
Mohammadi E, Dashti S, Shafizade N, ..., Mardinoglu A, Sekhavati MH
NPJ Syst Biol Appl 10 (1) 37 [2024-04-08; online 2024-04-08]
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The Discovery of New Inhibitors of Insulin-Regulated Aminopeptidase by a High-Throughput Screening of 400,000 Drug-like Compounds.
Gising J, Honarnejad S, Bras M, ..., Hallberg M, Larhed M
Int J Mol Sci 25 (7) - [2024-04-06; online 2024-04-06]
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Sulfone-based human liver pyruvate kinase inhibitors - Design, synthesis and in vitro bioactivity.
Matić J, Akladios F, Battisti UM, ..., Uhlen M, Grøtli M
Eur J Med Chem 269 (-) 116306 [2024-04-05; online 2024-03-05]
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Biosynthesis of Hesperetin, Homoeriodictyol, and Homohesperetin in a Transcriptomics-Driven Engineered Strain of Streptomyces albidoflavus.
Pérez-Valero Á, Serna-Diestro J, Tafur Rangel A, ..., Villar CJ, Lombó F
Int J Mol Sci 25 (7) - [2024-04-05; online 2024-04-05]
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Author Response: Activity modulation in anaerobic ribonucleotide reductases: nucleotide binding to the ATP-cone allosterically mediates substrate binding to the active site
Bimaï O, Banerjee I, Grinberg IR, ..., Sjöberg BM, Logan DT
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DOI Crossref
Activity modulation in anaerobic ribonucleotide reductases: nucleotide binding to the ATP-cone allosterically mediates substrate binding to the active site
Bimaï O, Banerjee I, Grinberg IR, ..., Sjöberg BM, Logan DT
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Identification of New Ketamine Metabolites and Their Detailed Distribution in the Mammalian Brain.
Vallianatou T, de Souza Anselmo C, Tsiara I, ..., Lundgaard I, Globisch D
ACS Chem Neurosci 15 (7) 1335-1341 [2024-04-03; online 2024-03-20]
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White horses - non-coding sequences drive premature hair greying and predisposition to melanoma.
Andersson L
Ups. J. Med. Sci. 129 (-) - [2024-04-02; online 2024-04-02]
PubMed DOI Crossref
Utilizing developmental dynamics for evolutionary prediction and control.
Milocco L, Uller T
Proc. Natl. Acad. Sci. U.S.A. 121 (14) e2320413121 [2024-04-02; online 2024-03-26]
DDLS Fellow Lisandro Milocco
DOI Crossref
Rücktitelbild: Rapid and Bifunctional Chemoselective Metabolome Analysis of Liver Disease Plasma Using the Reagent 4‐Nitrophenyl‐2‐azirine (Angew. Chem. 14/2024)
Lin W, Gerullat L, Braadland PR, ..., Hov JR, Globisch D
Angewandte Chemie 136 (14) - [2024-04-02; online 2024-02-29]
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Rapid and Bifunctional Chemoselective Metabolome Analysis of Liver Disease Plasma Using the Reagent 4‐Nitrophenyl‐2‐azirine
Lin W, Gerullat L, Braadland PR, ..., Hov JR, Globisch D
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Angewandte Chemie International Edition 63 (14) - [2024-04-02; online 2024-02-29]
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Birukov A, Guasch-Ferré M, Ley SH, ..., Hu FB, Zhang C
Diabetes Care 47 (4) 720-728 [2024-04-01; online 2024-02-20]
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Senftleben ML, Bajor A, Hirata E, Abrahamsson S, Brismar H
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Unexpected effect of halogenation on the water solubility of small organic compounds.
Zhang J, Gulyás KV, Li J, ..., Zhu W, Xu Z
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Ruisheng Xiong SciLifeLab Fellow
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Terlipressin therapy is associated with increased risk of colonisation with multidrug-resistant bacteria in patients with decompensated cirrhosis.
Mücke MM, Hernández-Tejero M, Gu W, ..., Trebicka J, MICROB-PREDICT and PREDICT Study Group of the EASL-CLIF Consortium
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Spatial landmark detection and tissue registration with deep learning.
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Single-cell omics analysis with genome-scale metabolic modeling.
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Siegel PB, Honaker CF, Andersson L
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Quantitative imaging of doxorubicin diffusion and cellular uptake in biomimetic gels with human liver tumor cells.
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Mullett MS, Harris AR, Scanu B, ..., Heungens K, Jung T
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Karunarathne P, Zhou Q, Lascoux M, Milesi P
Glob Chang Biol 30 (4) e17262 [2024-04-00; online 2024-03-28]
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Mol. Ecol. 33 (8) e17329 [2024-04-00; online 2024-03-27]
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Alvarado Obando M, Rey-Varela D, Cava F, Dörr T
PLoS Genet 20 (4) e1011234 [2024-04-00; online 2024-04-10]
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Prieto-Díaz R, Fojo-Carballo H, Majellaro M, ..., Gutiérrez-de-Terán H, Sotelo E
Biomed. Pharmacother. 173 (-) 116345 [2024-04-00; online 2024-03-05]
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Sommerauer C, Gallardo-Dodd CJ, Savva C, ..., Williams C, Kutter C
Mol Syst Biol 20 (4) 374-402 [2024-04-00; online 2024-03-08]
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Silao FGS, Valeriano VD, Uddström E, Falconer E, Ljungdahl PO
Mol. Microbiol. 121 (4) 696-716 [2024-04-00; online 2024-01-04]
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Ernst C, Andreassen PR, Giger GH, ..., Hardt WD, Vorholt JA
PLoS Biol. 22 (4) e3002597 [2024-04-00; online 2024-04-29]
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Claret JL, Di-Liegro M, Namias A, ..., Milesi P, Labbé P
Heredity (Edinb) 132 (4) 179-191 [2024-04-00; online 2024-01-27]
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Frommelt F, Fossati A, Uliana F, ..., Ciuffa R, Gstaiger M
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Andrea Fossati DDLS Fellow
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Kemas AM, Zandi Shafagh R, Taebnia N, ..., Hofmann U, Lauschke VM
Adv Healthc Mater 13 (11) e2303561 [2024-04-00; online 2023-12-10]
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Naseri S, Cordova MM, Wenthe J, ..., Loskog A, Ullenhag GJ
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Therriault J, Schindler SE, Salvadó G, ..., Jack CR, Rosa-Neto P
Nat Rev Neurol 20 (4) 232-244 [2024-04-00; online 2024-03-01]
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Automated model building and protein identification in cryo-EM maps.
Jamali K, Käll L, Zhang R, ..., Kimanius D, Scheres SHW
Nature 628 (8007) 450-457 [2024-04-00; online 2024-02-26]
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Sci Bull (Beijing) 69 (6) 803-822 [2024-03-30; online 2024-01-19]
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Two Different Strategies for Stabilization of Brain Tissue and Extraction of Neuropeptides.
Fridjonsdottir E, Nilsson A, Fricker LD, Andrén PE
Methods in molecular biology (Clifton, N.J.) 2758 (-) 49-60 [2024-03-29; online 2024-03-29]
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Eisele AS, Tarbier M, Dormann AA, Pelechano V, Suter DM
Nat Commun 15 (1) 2744 [2024-03-29; online 2024-03-29]
DDLS Fellow Marcel Tarbier
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Karami M, Soltani Mohammadi A, Martin M, ..., Patro R, Sahlin K
Bioinformatics 40 (4) - [2024-03-29; online 2024-04-05]
Kristoffer Sahlin SciLifeLab Fellow
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Best practices for the execution, analysis, and data storage of plant single-cell/nucleus transcriptomics.
Grones C, Eekhout T, Shi D, ..., Libault M, De Rybel B
Plant Cell 36 (4) 812-828 [2024-03-29; online 2024-01-17]
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Low coverage of species constrains the use of DNA barcoding to assess mosquito biodiversity.
Moraes Zenker M, Portella TP, Pessoa FAC, Bengtsson-Palme J, Galetti PM
Sci Rep 14 (1) 7432 [2024-03-28; online 2024-03-28]
DDLS Fellow Johan Bengtsson-Palme
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Vaccines (Basel) 12 (4) - [2024-03-27; online 2024-03-27]
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Unboxing the network among long non-coding RNAs and TGF-β signaling in cancer.
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Salmonella T3SS-2 virulence enhances gut-luminal colonization by enabling chemotaxis-dependent exploitation of intestinal inflammation.
Gül E, Huuskonen J, Abi Younes A, ..., Bakkeren E, Hardt WD
Cell Reports 43 (3) 113925 [2024-03-26; online 2024-03-07]
Mikael Sellin SciLifeLab Fellow
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ProQ-dependent activation of Salmonella virulence genes mediated by post-transcriptional control of PhoP synthesis.
Bergman S, Andresen L, Kjellin J, ..., Sellin ME, Holmqvist E
mSphere 9 (3) e0001824 [2024-03-26; online 2024-02-27]
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Jou-Claus S, Rodríguez-Escales P, Martínez-Landa L, ..., Quintana G, Valhondo C
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NEDD8 loss causes cancer vulnerability to immune checkpoint blockade in triple-negative breast cancer
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Corrigendum: Development of new approach methods for the identification and characterization of endocrine metabolic disruptors-a PARC project.
Braeuning A, Balaguer P, Bourguet W, ..., Wewer N, Zalko D
Front Toxicol 6 (-) 1394396 [2024-03-25; online 2024-03-25]
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A Comprehensive Analysis of the Effect of A>I(G) RNA-Editing Sites on Genotoxic Drug Response and Progression in Breast Cancer.
Bernal YA, Blanco A, Sagredo EA, ..., Marcelain K, Armisén R
Biomedicines 12 (4) - [2024-03-25; online 2024-03-25]
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Influence of Molecular Design on the Tumor Targeting and Biodistribution of PSMA-Binding Tracers Labeled with Technetium-99m.
Bezverkhniaia E, Kanellopoulos P, Rosenström U, Tolmachev V, Orlova A
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Abstract 7287: High-grade serous ovarian carcinoma detected with TP53 mutation panel and SiMSen-Seq
Widjaja AO, Micallef P, Ulfenborg B, ..., Linder A, Sundfeldt K
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Abstract 3100: Interactive analysis of drug testing data for functional precision oncology with Breeze 2.0
Potdar S, Ianevski F, Ianevski A, ..., Aittokallio T, Saarela J
Cancer Res. 84 (6_Supplement) 3100-3100 [2024-03-22; online 2024-03-22]
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Contrasting segregation patterns among endogenous retroviruses across the koala population.
Lillie M, Pettersson M, Jern P
Commun Biol 7 (1) 350 [2024-03-21; online 2024-03-21]
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Cluster-free annotation of single cells using Earth mover’s distance-based classification
Forlin R, Tajvar P, Wang N, Dimarogonas D, Brodin P
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Caveolin-1 gene expression provides additional prognostic information combined with PAM50 risk of recurrence (ROR) score in breast cancer.
Godina C, Belting M, Vallon-Christersson J, ..., Bosch A, Jernström H
Sci Rep 14 (1) 6675 [2024-03-20; online 2024-03-20]
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Neural network informed photon filtering reduces fluorescence correlation spectroscopy artifacts.
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Near-wall depletion and layering affect contact line friction of multicomponent liquids
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Identification of novel and potent inhibitors of SARS-CoV-2 main protease from DNA-encoded chemical libraries
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Chloroplastic ascorbate acts as a regulatory hub in plant metabolism regardless of oxidative stress
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Glutamine deprivation alters TGF-β signaling in hepatocellular carcinoma
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Is GBA1 T369M not a risk factor for Parkinson's disease in the Swedish population?
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Maintenance of cell wall remodeling and vesicle production are connected in Mycobacterium tuberculosis
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Boundary cap neural crest stem cells promote angiogenesis after transplantation to avulsed dorsal roots in mice and induce migration of endothelial cells in 3D printed scaffolds.
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Gustaf Christoffersson SciLifeLab Fellow
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Author Response: Maintenance of cell wall remodeling and vesicle production are connected in Mycobacterium tuberculosis
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Spatial Dynamics of the Developing Human Heart
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Regulation of meiotic telomere dynamics through membrane fluidity promoted by AdipoR2-ELOVL2.
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Medically relevant tandem repeats in nanopore sequencing of control cohorts
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The impact of genetically controlled splicing on exon inclusion and protein structure.
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Structural constraints on the emergence of oscillations in multi-population neural networks.
Zang J, Liu S, Helson P, Kumar A
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Structural constraints on the emergence of oscillations in multi-population neural networks
Zang J, Liu S, Helson P, Kumar A
Elife 12 (-) - [2024-03-13; online 2024-03-13]
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Identification of a new gregarine parasite associated with mass mortality events of freshwater pearl mussels (Margaritifera margaritifera) in Sweden.
Alfjorden A, Onut-Brännström I, Wengström N, ..., Persson BD, Burki F
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Genome wide association study in Swedish Labrador retrievers identifies genetic loci associated with hip dysplasia and body weight.
Kieler IN, Persson SM, Hagman R, ..., Lindblad-Toh K, Arendt ML
Sci Rep 14 (1) 6090 [2024-03-13; online 2024-03-13]
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Transcriptome Analysis Reveals Distinct Patterns Between the Invasive and Noninvasive Pituitary Neuroendocrine Tumors.
Jotanovic J, Tebani A, Hekmati N, ..., Pontén F, Casar-Borota O
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Ribosomes modulate transcriptome abundance via generalized frameshift and out-of-frame mRNA decay
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Neutralizing IFN-γ autoantibodies are rare and pathogenic in HLA-DRB1*15:02 or 16:02 individuals.
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Vascular characterization reveals immunomodulatory targets for brain metastases.
Lugano R, Dimberg A
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U-FISH: a universal deep learning approach for accurate FISH spot detection across diverse datasets
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An efficient protocol for extracting thylakoid membranes and total leaf proteins from Posidonia oceanica and other polyphenol-rich plants.
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Plasma metabolites of a healthy lifestyle in relation to mortality and longevity: Four prospective US cohort studies.
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Clemens Wittenbecher DDLS Fellow
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Twenty years on from Developmental Plasticity and Evolution: middle-range theories and how to test them.
Uller T, Milocco L, Isanta-Navarro J, Cornwallis CK, Feiner N
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Protein biomarkers and alternatively methylated cell-free DNA detect early stage pancreatic cancer.
Ben-Ami R, Wang QL, Zhang J, ..., Dor Y, Wolpin BM
Gut 73 (4) 639-648 [2024-03-07; online 2024-03-07]
DDLS Fellow Qiaoli Wang
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Essential role of local antibody distribution in mediating bone-resorbing effects.
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Clonal haematopoiesis of indeterminate potential predicts incident cardiac arrhythmias.
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Investigating the efficacy of green solvents and solvent-free conditions in hydrogen-bonding mediated organocatalyzed model reactions.
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An Allosteric Cholesterol Site in Glycine Receptors Characterized Through Molecular Simulations
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Linear epitopes of bony fish β-parvalbumins.
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Immuno-oncological effects of standard anticancer agents and commonly used concomitant drugs: an in vitro assessment.
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BMC Pharmacol Toxicol 25 (1) 25 [2024-03-05; online 2024-03-05]
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CD93 maintains endothelial barrier function and limits metastatic dissemination.
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A role for the S4-domain containing protein YlmH in ribosome-associated quality control in Bacillus subtilis
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Conformal prediction enables disease course prediction and allows individualized diagnostic uncertainty in multiple sclerosis
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The Calvin Benson cycle in bacteria: New insights from systems biology.
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Patient-Centric Quantitative Microsampling for Accurate Determination of Urine Albumin to Creatinine Ratio (UACR) in a Clinical Setting.
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From pixels to phenotypes: Integrating image-based profiling with cell health data as BioMorph features improves interpretability.
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Asymmetric T-cell division: insights from cutting-edge experimental techniques and implications for immunotherapy.
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VE-cadherin junction dynamics in initial lymphatic vessels promotes lymph node metastasis.
Sáinz-Jaspeado M, Ring S, Proulx ST, ..., Ulvmar MH, Jin Y
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Uncovering driver genes in breast cancer through an innovative machine learning mutational analysis method.
Taheri G, Habibi M
Comput Biol Med 171 (-) 108234 [2024-03-00; online 2024-02-29]
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P13 Acquired ficolin-3 deficiency in patients with systemic lupus erythematosus
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DEPICTER: Deep representation clustering for histology annotation.
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Abhishek Niroula DDLS Fellow
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Genetic and molecular architecture of complex traits.
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Risk factors for clonal hematopoiesis of indeterminate potential in people with HIV: a report from the REPRIEVE trial.
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Predictive biomarkers of rapidly developing insulin deficiency in children with type 1 diabetes.
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Equine enteroid-derived monolayers recapitulate key features of parasitic intestinal nematode infection.
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Decoding of the surfaceome and endocytome in primary glioblastoma cells identifies potential target antigens in the hypoxic tumor niche.
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Spatial Neurolipidomics at the Single Amyloid-β Plaque Level in Postmortem Human Alzheimer's Disease Brain.
Michno W, Bowman A, Jha D, ..., Heeren RMA, Hanrieder J
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Limited parallelism in genetic adaptation to brackish water bodies in European sprat and Atlantic herring
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Toward ovarian cancer screening with protein biomarkers using dried, self-sampled cervico-vaginal fluid.
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iScience 27 (2) 109001 [2024-02-16; online 2024-01-24]
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Targeting the Main Protease (Mpro, nsp5) by Growth of Fragment Scaffolds Exploiting Structure-Based Methodologies.
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Community stability increases the predictability of microeukaryote community coalescence outcomes
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Castillejo-López C, Bárcenas-Walls JR, Cavalli M, Larsson A, Wadelius C
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RhoB expression associated with chemotherapy response and prognosis in colorectal cancer.
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Prevalent and persistent new-onset autoantibodies in mild to severe COVID-19
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BMC Biol. 22 (1) 36 [2024-02-14; online 2024-02-14]
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Targeting MYC induces lipid droplet accumulation by upregulation of HILPDA in clear cell renal cell carcinoma.
Sainero-Alcolado L, Garde-Lapido E, Snaebjörnsson MT, ..., Schulze A, Arsenian-Henriksson M
Proc. Natl. Acad. Sci. U.S.A. 121 (7) e2310479121 [2024-02-13; online 2024-02-09]
SciLifeLab Fellow Vicent Pelechano
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Most axonal mitochondria in cortical pyramidal neurons lack mitochondrial DNA and consume ATP.
Hirabayashi Y, Lewis TL, Du Y, ..., Testa I, Polleux F
bioRxiv - (-) - [2024-02-13; online 2024-02-13]
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CSF protein ratios with enhanced potential to reflect Alzheimer's disease pathology and neurodegeneration.
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Mol Neurodegener 19 (1) 15 [2024-02-13; online 2024-02-13]
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A distinctive family of L,D-transpeptidases catalyzing L-Ala-mDAP crosslinks in Alpha- and Betaproteobacteria.
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phbuilder: A Tool for Efficiently Setting up Constant pH Molecular Dynamics Simulations in GROMACS.
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Identification of a gene network driving the attenuated response to lipopolysaccharide of monocytes from hypertensive coronary artery disease patients.
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A high-resolution spatial map of cilia-associated proteins based on characterization of the human fallopian tube-specific proteome
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Prelude to Malignancy: A Gene Expression Signature in Normal Mammary Gland from Breast Cancer Patients Suggests Pre-tumorous Alterations and Is Associated with Adverse Outcomes
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Covalent bicyclization of protein complexes yields durable quaternary structures.
Hutchins GH, Kiehstaller S, Poc P, ..., Hennig S, Grossmann TN
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2D MXene electrochemical transistors.
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Structural basis for the oligomerization-facilitated NLRP3 activation.
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PKSmart: An Open-Source Computational Model to Predict in vivo Pharmacokinetics of Small Molecules
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Immune mapping of human tuberculosis and sarcoidosis lung granulomas.
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Author Correction: Direct RNA targeted in situ sequencing for transcriptomic profiling in tissue.
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Editorial: Footprints of immune cells in the type 1 diabetic pancreas, volume II.
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Single-molecule chromatin configurations link transcription factor binding to expression in human cells.
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Microfluidics and Organ-on-a-Chip for Disease Modeling and Drug Screening.
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Noninvasive PET Detection of CD69-Positive Immune Cells Before Signs of Clinical Disease in Inflammatory Arthritis.
Puuvuori E, Shen Y, Hulsart-Billström G, ..., Wermeling F, Eriksson O
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 65 (2) 294-299 [2024-02-01; online 2024-02-01]
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Pain 165 (2) 324-336 [2024-02-01; online 2023-08-11]
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ClusTrast: a short read de novo transcript isoform assembler guided by clustered contigs.
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BMC Bioinformatics 25 (1) 54 [2024-02-01; online 2024-02-01]
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Wildlife endogenous retroviruses: colonization, consequences, and cooption.
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Trends in Genetics 40 (2) 149-159 [2024-02-00; online 2023-11-19]
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The Pseudomonas aeruginosa lectin LecB modulates intracellular reactive oxygen species production in human neutrophils.
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Stress biology: Complexity and multifariousness in health and disease.
Mayer MP, Blair L, Blatch GL, ..., Wang SXY, Zininga T
Cell Stress Chaperones 29 (1) 143-157 [2024-02-00; online 2024-02-03]
Anniina Vihervaara SciLifeLab Fellow
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Strategies to decrease inequalities in cancer therapeutics, care and prevention: Proceedings on a conference organized by the Pontifical Academy of Sciences and the European Academy of Cancer Sciences, Vatican City, February 23-24, 2023.
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Sfrp1 inhibits lung fibroblast invasion during transition to injury-induced myofibroblasts.
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Reconstruction of genome-scale metabolic models of non-conventional yeasts: current state, challenges, and perspectives
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Biotechnol Bioproc E 29 (1) 35-67 [2024-02-00; online 2024-02-13]
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Predicting COVID-19 hospitalizations: The importance of healthcare hotlines, test positivity rates and vaccination coverage.
van Zoest V, Lindberg K, Varotsis G, Osei FB, Fall T
Spat Spatiotemporal Epidemiol 48 (-) 100636 [2024-02-00; online 2024-01-17]
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Porcine circovirus type 2 infection promotes the SUMOylation of nucleophosmin-1 to facilitate the viral circular single-stranded DNA replication.
Du Q, Zhu L, Zhong J, ..., Tong D, Huang Y
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Plasma metabolite predictors of metabolic syndrome incidence and reversion.
Semnani-Azad Z, Toledo E, Babio N, ..., Hu FB, Guasch-Ferré M
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On proving that an unsafe controller is not proven safe
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Journal of Logical and Algebraic Methods in Programming 137 (-) 100939 [2024-02-00; online 2024-02-00]
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Multivalent insulin receptor activation using insulin-DNA origami nanostructures.
Spratt J, Dias JM, Kolonelou C, ..., Ruas JL, Teixeira AI
Nat Nanotechnol 19 (2) 237-245 [2024-02-00; online 2023-10-09]
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Ion and lipid orchestration of secondary active transport.
Drew D, Boudker O
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Intrinsic deletion at 10q23.31, including the PTEN gene locus, is aggravated upon CRISPR-Cas9-mediated genome engineering in HAP1 cells mimicking cancer profiles.
Geng K, Merino LG, Veiga RG, ..., Brinkman EK, Kutter C
Life Sci. Alliance 7 (2) - [2024-02-00; online 2023-11-20]
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PubMed DOI Crossref
Humoral immune responses to the monovalent XBB.1.5-adapted BNT162b2 mRNA booster in Sweden.
Marking U, Bladh O, Aguilera K, ..., Sheward DJ, Thålin C
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High-throughput and multi-parametric biophysical cell phenotyping with smart probes
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Biophysical Journal 123 (3) 449a-450a [2024-02-00; online 2024-02-00]
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High-content screening of drug combinations of an mPGES-1 inhibitor in multicellular tumor spheroids leads to mechanistic insights into neuroblastoma chemoresistance.
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Electroporation of bacteria in microfluidic device
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Effects of exercise on whole-blood transcriptome profile in children with overweight/obesity.
Altmäe S, Plaza-Florido A, Esteban FJ, ..., Radom-Aizik S, Ortega FB
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Editorial overview: Computational neuroscience as a bridge between artificial intelligence, modeling and data.
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Determining protein conformational ensembles by combining machine learning and small-angle scattering
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Antisecretory factor in breastmilk is associated with reduced incidence of sepsis in preterm infants.
Gustafsson A, Johansson E, Henckel E, ..., Lange S, Bohlin K
Pediatr. Res. 95 (3) 762-769 [2024-02-00; online 2023-11-24]
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ATG12-ATG5-TECPR1: an alternative E3-like complex utilized during the cellular response to lysosomal membrane damage.
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A peptidoglycan N-deacetylase specific for anhydroMurNAc chain termini in Agrobacterium tumefaciens.
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A Perfusable Multi‐Hydrogel Vasculature On‐Chip Engineered by 2‐Photon 3D Printing and Scaffold Molding to Improve Microfabrication Fidelity in Hydrogels
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ESPressoscope: a small and powerful platform for in situ microscopy
Li E, Saggiomo V, Ouyang W, Prakash M, Diederich B
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Discovery of lipid binding sites in a ligand-gated ion channel by integrating simulations and cryo-EM.
Bergh C, Rovšnik U, Howard R, Lindahl E
Elife 12 (-) - [2024-01-30; online 2024-01-30]
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A two-step activation mechanism enables mast cells to differentiate their response between extracellular and invasive enterobacterial infection.
von Beek C, Fahlgren A, Geiser P, ..., Pejler G, Sellin ME
Nat Commun 15 (1) 904 [2024-01-30; online 2024-01-30]
Mikael Sellin SciLifeLab Fellow
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Interactive computational and experimental approaches improve the sensitivity of periplasmic binding protein-based nicotine biosensors for measurements in biofluids.
Haloi N, Huang S, Nichols AL, ..., Mayo SL, Lester HA
Protein Eng. Des. Sel. 37 (-) - [2024-01-29; online 2024-02-02]
PubMed DOI Crossref
AutoTransOP: translating omics signatures without orthologue requirements using deep learning.
Meimetis N, Pullen KM, Zhu DY, ..., Magliacane S, Lauffenburger DA
NPJ Syst Biol Appl 10 (1) 13 [2024-01-29; online 2024-01-29]
Avlant Nilsson DDLS Fellow
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Sensitive and Specific Analyses of Colorectal Cancer Recurrence through Multiplex superRCA Mutation Detection in Blood Plasma.
Sandberg E, Nunes L, Edqvist PH, ..., Landegren U, Sjöblom T
Cancers (Basel) 16 (3) - [2024-01-27; online 2024-01-27]
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Sex-Specific Associations between Prenatal Exposure to Di(2-ethylhexyl) Phthalate, Epigenetic Age Acceleration, and Susceptibility to Early Childhood Upper Respiratory Infections.
Merrill SM, Letourneau N, Giesbrecht GF, ..., Dewey D, England-Mason G
Epigenomes 8 (1) - [2024-01-26; online 2024-01-26]
DOI Crossref
SMAC mimetics overcome apoptotic resistance in ovarian cancer through MSLN-TNF alpha axis
Coelho R, Seashore-Ludlow B, Schütz S, ..., Heinzelmann-Schwarz V, Jacob F
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DOI Crossref
Resolution of ribosomal stalling by ABCF ATPases YfmR and YkpA/YbiT
Takada H, Fujiwara K, Atkinson GC, Shinobu C, Hauryliuk V
- - (-) - [2024-01-26; online 2024-01-26]
DOI Crossref
Divergent mechanisms of steroid inhibition in the human ρ1 GABA A receptor
Fan C, Cowgill J, Howard RJ, Lindahl E
- - (-) - [2024-01-26; online 2024-01-26]
DOI Crossref
Continental scientific drilling and microbiology: (extremely) low biomass in bedrock of central Sweden
Westmeijer G, Escudero C, Bergin C, ..., Bertilsson S, Dopson M
Biogeosciences 21 (2) 591-604 [2024-01-26; online 2024-01-26]
PubMed DOI Crossref
Comparative genomic analyses provide new insights into evolutionary history and conservation genomics of gorillas.
van der Valk T, Jensen A, Caillaud D, Guschanski K
BMC Ecol Evol 24 (1) 14 [2024-01-26; online 2024-01-26]
PubMed DOI Crossref
Association of genetic variation in COL11A1 with adolescent idiopathic scoliosis.
Yu H, Khanshour AM, Ushiki A, ..., Ahituv N, Wise CA
Elife 12 (-) - [2024-01-26; online 2024-01-26]
PubMed DOI Crossref
tRNA shape is an identity element for an archaeal pyrrolysyl-tRNA synthetase from the human gut.
Krahn N, Zhang J, Melnikov SV, ..., Puglisi J, Söll D
Nucleic Acids Res. 52 (2) 513-524 [2024-01-25; online 2023-12-15]
DOI Crossref
High-parametric protein maps reveal the spatial organization in early-developing human lung
Sariyar S, Sountoulidis A, Hansen JN, ..., Lundberg E, Ayoglu B
- - (-) - [2024-01-25; online 2024-01-25]
PubMed DOI Crossref
Escherichia coli CadB is capable of promiscuously transporting muropeptides and contributing to peptidoglycan recycling.
Simpson BW, Gilmore MC, McLean AB, Cava F, Trent MS
J. Bacteriol. 206 (1) e0036923 [2024-01-25; online 2024-01-03]
DOI Crossref
Personalized oral care (Precaries): an intervention study customized according to genetic cause and risk
Westerlund A, Khalifa H, Yousif R, ..., Larsson P, Strömberg N
- - (-) - [2024-01-24; online 2024-01-24]
PubMed DOI Crossref
Integration of multiple flexible electrodes for real-time detection of barrier formation with spatial resolution in a gut-on-chip system.
Lucchetti M, Werr G, Johansson S, ..., Wilmes P, Tenje M
Microsyst. Nanoeng. 10 (-) 18 [2024-01-24; online 2024-01-24]
DOI Crossref
Comparison of the performance of multiple whole-genome sequence-based tools for the identification of Bacillus cereus sensu stricto biovar Thuringiensis
Chung T, Salazar A, Harm G, ..., Carroll LM, Kovac J
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DOI Crossref
READv2: Advanced and user-friendly detection of biological relatedness in archaeogenomics
Alaçamlı E, Naidoo T, Aktürk Ş, ..., Malmström H, Günther T
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PubMed DOI Crossref
Immunomodulatory Nanoparticles for Modulating Arthritis Flares.
Johnson WT, McBride D, Kerr M, ..., Bottini N, Shah NJ
ACS Nano 18 (3) 1892-1906 [2024-01-23; online 2023-11-28]
PubMed DOI Crossref
Cancer Diagnoses After Recent Weight Loss.
Wang QL, Babic A, Rosenthal MH, ..., Yuan C, Wolpin BM
JAMA 331 (4) 318-328 [2024-01-23; online 2024-01-23]
DDLS Fellow Qiaoli Wang
PubMed DOI Crossref
A New Synthesized Dicarboxylated Oxy-Heparin Efficiently Attenuates Tumor Growth and Metastasis.
Li L, Barash U, Ilan N, ..., Vlodavsky I, Li JP
Cells 13 (3) - [2024-01-23; online 2024-01-23]
PubMed DOI Crossref
Benchmarking enrichment analysis methods with the disease pathway network.
Buzzao D, Castresana-Aguirre M, Guala D, Sonnhammer ELL
Brief. Bioinformatics 25 (2) - [2024-01-22; online 2024-03-04]
PubMed DOI Crossref
Soluble and multivalent Jag1 DNA origami nanopatterns activate Notch without pulling force.
Smyrlaki I, Fördős F, Rocamonde-Lago I, ..., Teixeira AI, Högberg B
Nat Commun 15 (1) 465 [2024-01-18; online 2024-01-18]
Antonio Lentini DDLS Fellow
PubMed DOI Crossref
Interactive computational and experimental approaches improve the sensitivity of periplasmic binding protein-based nicotine biosensors for measurements in biofluids.
Haloi N, Huang S, Nichols AL, ..., Mayo SL, Lester HA
bioRxiv - (-) - [2024-01-18; online 2024-01-18]
PubMed DOI Crossref
Response by Sayols-Baixeras et al to Letter Regarding Article, "Streptococcus Species Abundance in the Gut Is Linked to Subclinical Coronary Atherosclerosis in 8973 Participants From the SCAPIS Cohort".
Sayols-Baixeras S, Dekkers KF, Orho-Melander M, Fall T
Circulation 149 (3) 276 [2024-01-16; online 2024-01-16]
PubMed DOI Crossref
A structurally precise mechanism links an epilepsy-associated KCNC2 potassium channel mutation to interneuron dysfunction.
Clatot J, Currin CB, Liang Q, ..., Covarrubias M, Goldberg EM
Proc. Natl. Acad. Sci. U.S.A. 121 (3) e2307776121 [2024-01-16; online 2024-01-09]
Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Impaired spermatogenesis and associated endocrine effects of azole fungicides in peripubertal Xenopus tropicalis.
Svanholm S, Brouard V, Roza M, ..., Karlsson O, Berg C
Ecotoxicology and Environmental Safety 270 (-) 115876 [2024-01-15; online 2023-12-27]
DOI Crossref
Bridging the Gap: Integrating Cutting-edge Techniques into Biological Imaging with deepImageJ
Fuster-Barceló C, García López de Haro C, Gómez-de-Mariscal E, ..., Sage D, Muñoz-Barrutia A
- - (-) - [2024-01-15; online 2024-01-15]
PubMed DOI Crossref
Observation of a single protein by ultrafast X-ray diffraction.
Ekeberg T, Assalauova D, Bielecki J, ..., Meyer M, Maia FRNC
Light Sci Appl 13 (1) 15 [2024-01-12; online 2024-01-12]
PubMed DOI Crossref
Universal Biomaterial-on-Chip: a versatile platform for evaluating cellular responses on diverse biomaterial substrates.
Atif AR, Aramesh M, Carter SS, Tenje M, Mestres G
J Mater Sci Mater Med 35 (1) 2 [2024-01-11; online 2024-01-11]
DOI Crossref
Sensitive and Specific Analyses of Colorectal Cancer Recurrence through Multiplex superRCA Mutation Detection in Blood Plasma
Sandberg E, Nunes L, Edqvist PH, ..., Landegren U, Sjöblom T
- - (-) - [2024-01-11; online 2024-01-11]
PubMed DOI Crossref
Precision microbial intervention improves social behavior but not autism severity: A pilot double-blind randomized placebo-controlled trial.
Mazzone L, Dooling SW, Volpe E, ..., Costa-Mattioli M, Hardan AY
Cell Host Microbe 32 (1) 106-116.e6 [2024-01-10; online 2023-12-18]
PubMed DOI Crossref
Introduction of a fatty acid chain modification to prolong circulatory half-life of a radioligand towards glucose-dependent insulinotropic polypeptide receptor.
Khalil A, Hakhverdyan S, Cheung P, ..., Eriksson O, Velikyan I
Nucl. Med. Biol. 128-129 (-) 108876 [2024-01-10; online 2024-01-10]
PubMed DOI Crossref
Viral proteins activate PARIS-mediated tRNA degradation and viral tRNAs rescue infection.
Burman N, Belukhina S, Depardieu F, ..., Wiedenheft B, Isaev A
bioRxiv - (-) - [2024-01-09; online 2024-01-09]
PubMed DOI Crossref
Multilayer DNA Origami with Terminal Interfaces That Are Flat and Wide-Area.
Kilwing L, Lill P, Nathwani B, ..., Liedl T, Shih WM
ACS Nano 18 (1) 885-893 [2024-01-09; online 2023-12-18]
Erik Benson SciLifeLab Fellow
DOI Crossref
High-Throughput DNA melt measurements enable improved models of DNA folding thermodynamics
Ke Y, Sharma E, Wayment-Steele HK, ..., Marklund E, Greenleaf WJ
- - (-) - [2024-01-09; online 2024-01-09]
PubMed DOI Crossref
All SNAP25 molecules in the vesicle-plasma membrane contact zone change conformation during vesicle priming.
Zhao Y, Fang Q, Sharma S, ..., Jahn R, Lindau M
Proc. Natl. Acad. Sci. U.S.A. 121 (2) e2309161121 [2024-01-09; online 2024-01-03]
PubMed DOI Crossref
Investigating chromosomal instability in long-term survivors with glioblastoma and grade 4 astrocytoma.
Spoor JKH, den Braber M, Dirven CMF, ..., Leenstra S, Venkatesan S
Front Oncol 13 (-) 1218297 [2024-01-08; online 2024-01-08]
PubMed DOI Crossref
Geographic population structure and distinct intra-population dynamics of globally abundant freshwater bacteria.
Hoetzinger M, Hahn MW, Andersson LY, ..., Puente-Sánchez F, Bertilsson S
ISME J 18 (1) - [2024-01-08; online 2024-07-04]
PubMed DOI Crossref
GDF15 Protects Insulin-Producing Beta Cells against Pro-Inflammatory Cytokines and Metabolic Stress via Increased Deamination of Intracellular Adenosine.
Ngamjariyawat A, Cen J, Wang X, Welsh N
Int J Mol Sci 25 (2) - [2024-01-08; online 2024-01-08]
DOI Crossref
Discovery of lipid binding sites in a ligand-gated ion channel by integrating simulations and cryo-EM
Bergh C, Rovšnik U, Howard RJ, Lindahl E
- - (-) - [2024-01-05; online 2024-01-05]
DOI Crossref
Author Response: Discovery of lipid binding sites in a ligand-gated ion channel by integrating simulations and cryo-EM
Bergh C, Rovšnik U, Howard RJ, Lindahl E
- - (-) - [2024-01-05; online 2024-01-05]
PubMed DOI Crossref
A cholesterol switch controls phospholipid scrambling by G protein-coupled receptors.
Menon I, Sych T, Son Y, ..., Levitz J, Menon AK
bioRxiv - (-) - [2024-01-05; online 2024-01-05]
PubMed DOI Crossref
Longevity interventions modulate mechanotransduction and extracellular matrix homeostasis in C. elegans.
Teuscher AC, Statzer C, Goyala A, ..., Aebersold R, Ewald CY
Nat Commun 15 (1) 276 [2024-01-04; online 2024-01-04]
Andrea Fossati DDLS Fellow
PubMed DOI Crossref
Interaction molecular QTL mapping discovers cellular and environmental modifiers of genetic regulatory effects.
Kasela S, Aguet F, Kim-Hellmuth S, ..., Barr RG, Lappalainen T
Am. J. Hum. Genet. 111 (1) 133-149 [2024-01-04; online 2024-01-06]
DOI Crossref
Deep learning insights into the architecture of the mammalian egg-sperm fusion synapse
Elofsson A, Han L, Bianchi E, Wright GJ, Jovine L
- - (-) - [2024-01-04; online 2024-01-04]
PubMed DOI Crossref
Compartmentalizing damaged DNA: A double-edged sword.
Georgiades E, Crosetto N, Bienko M
Mol. Cell 84 (1) 12-13 [2024-01-04; online 2024-01-06]
DOI Crossref
Bridging Generalization Gaps in High Content Imaging Through Online Self-Supervised Domain Adaptation
Haslum JF, Matsoukas C, Leuchowius KJ, Smith K
- - (-) 7723-7732 [2024-01-03; online 2024-01-03]
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Are Natural Domain Foundation Models Useful for Medical Image Classification?
Huix JP, Ganeshan AR, Haslum JF, ..., Matsoukas C, Smith K
- - (-) 7619-7628 [2024-01-03; online 2024-01-03]
PubMed DOI Crossref
Targeting MTHFD2 to Exploit Cancer-Specific Metabolism and the DNA Damage Response.
Ramos L, Henriksson M, Helleday T, Green AC
Cancer Res. 84 (1) 9-16 [2024-01-02; online 2023-11-03]
PubMed DOI Crossref
Pathway analysis through mutual information.
Jeuken GS, Käll L
Bioinformatics 40 (1) - [2024-01-02; online 2024-01-10]
PubMed DOI Crossref
M-Ionic: prediction of metal-ion-binding sites from sequence using residue embeddings.
Shenoy A, Kalakoti Y, Sundar D, Elofsson A
Bioinformatics 40 (1) - [2024-01-02; online 2024-01-04]
PubMed DOI Crossref
Clonal Hematopoiesis Risk Score and All-Cause and Cardiovascular Mortality in Older Adults.
Saadatagah S, Uddin MM, Weeks LD, ..., Natarajan P, Ballantyne CM
JAMA Netw Open 7 (1) e2351927 [2024-01-02; online 2024-01-02]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
Characterization and biological applications of gonadal extract of Paracentrotus lividus collected along the Mediterranean coast of Alexandria, Egypt.
Nagy NS, Essawy AE, Al-Sherif SS, ..., Alsawy ES, Helal M
PLoS ONE 19 (1) e0296312 [2024-01-02; online 2024-01-02]
PubMed DOI Crossref
Specifying cellular context of transcription factor regulons for exploring context-specific gene regulation programs.
Minaeva M, Domingo J, Rentzsch P, Lappalainen T
bioRxiv - (-) - [2024-01-01; online 2024-01-01]
PubMed DOI Crossref
Effect of mode of delivery of patient reported outcomes in patients with breast disease: a randomised controlled trial.
Pantiora E, Hedman LC, Aristokleous I, ..., Karakatsanis A, Schiza A
Int J Surg 110 (1) 176-182 [2024-01-01; online 2024-01-01]
PubMed DOI Crossref
Discovery and biological evaluation of novel dual PTP1B and ACP1 inhibitors for the treatment of insulin resistance.
Feng B, Zhang J, Liu Z, Xu Y, Hu H
Bioorg. Med. Chem. 97 (-) 117545 [2024-01-01; online 2023-12-06]
DOI Crossref
Beyond Basic Characterization and Omics: Immunomodulatory Roles of Platelet-Derived Extracellular Vesicles Unveiled by Functional Testing
Palviainen M, Puutio J, Østergaard RH, ..., Hayashi Y, Siljander PR
- - (-) - [2024-01-01; online 2024-01-01]
PubMed DOI Crossref
Tuning of CHO secretional machinery improve activity of secreted therapeutic sulfatase 150-fold.
Thalén NB, Barzadd MM, Lundqvist M, ..., Sandegren A, Rockberg J
Metab. Eng. 81 (-) 157-166 [2024-01-00; online 2023-12-09]
PubMed DOI Crossref
Treatment with a tissue-selective oestrogen complex does not affect disease pathology but reduces pre-BI cells in lupus-prone mice.
Drevinge C, Scheffler JM, Nordqvist J, ..., Carlsten H, Islander U
Scand J Rheumatol 53 (1) 49-58 [2024-01-00; online 2023-12-28]
PubMed DOI Crossref
Treatment utilization and effectiveness of neoadjuvant chemotherapy comparing men and women diagnosed with breast cancer: a Swedish retrospective cohort study.
Schiza A, Fredriksson I, Sund M, Valachis A
Breast Cancer Res. Treat. 203 (2) 235-243 [2024-01-00; online 2023-10-09]
PubMed DOI Crossref
The role of the 5' sensing function of ribonuclease E in cyanobacteria.
Hoffmann UA, Lichtenberg E, Rogh SN, ..., Hess WR, Wilde A
RNA Biol 21 (1) 1-18 [2024-01-00; online 2024-03-12]
DOI Crossref
One Year Weekly Size‐Resolved Air Sampling of SARS‐CoV‐2 in Hospital Corridors and Relations to the Indoor Environment
Thuresson S, Fraenkel CJ, Sasinovich S, ..., Alsved M, Löndahl J
Indoor Air 2024 (1) - [2024-01-00; online 2024-03-27]
PubMed DOI Crossref
Non-invasive imaging of sympathetic innervation of the pancreas in individuals with type 2 diabetes.
Vyakaranam AR, Mahamed MM, Hellman P, ..., Christoffersson G, Sundin A
Diabetologia 67 (1) 199-208 [2024-01-00; online 2023-11-07]
Daniel Espes Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
JDLL: a library to run deep learning models on Java bioimage informatics platforms.
García López de Haro C, Dallongeville S, Musset T, ..., Tinevez JY, Olivo-Marin JC
Nat. Methods 21 (1) 7-8 [2024-01-00; online 2024-01-09]
PubMed DOI Crossref
Gene expression of single cells mapped in tissue sections.
Ståhl PL
Nature 625 (7993) 38-39 [2024-01-00; online 2023-12-14]
PubMed DOI Crossref
Electroencephalography findings in menstrually-related mood disorders: A critical review.
Kaltsouni E, Schmidt F, Zsido RG, ..., Sumner RL, Comasco E
Front Neuroendocrinol 72 (-) 101120 [2024-01-00; online 2024-01-02]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Calcium-gated potassium channel blockade via membrane-facing fenestrations.
Fan C, Flood E, Sukomon N, ..., Allen TW, Nimigean CM
Nat. Chem. Biol. 20 (1) 52-61 [2024-01-00; online 2023-08-31]
PubMed DOI Crossref
Aberrant microbiomes are associated with increased antibiotic resistance gene load in hybrid mice.
Jarquín-Díaz VH, Ferreira SCM, Balard A, ..., Forslund-Startceva SK, Heitlinger E
ISME Commun 4 (1) ycae053 [2024-01-00; online 2024-04-15]
DDLS Fellow Johan Bengtsson-Palme
DOI Crossref
Transfer Learning-Assisted Inverse Modeling in Nanophotonics Based on Mixture Density Networks
Cheng L, Singh P, Ferranti F
IEEE Access 12 (-) 55218-55224 [2024-00-00; online 2024-00-00]
DOI Crossref
Toward safer and more sustainable by design biocatalytic amide-bond coupling
Söderberg E, von Borries K, Norinder U, ..., Fantke P, Syrén PO
Green Chem. 26 (22) 11147-11163 [2024-00-00; online 2024-00-00]
DOI Crossref
Spatial Transcriptomics Reveals an Unexpected Impact of Tau and Tau Pathology on the Expression of Transthyretin
Croteau DL, Navarro JF, Comptdaer T, ..., Lundeberg J, Galas MC
- - (-) - [2024-00-00; online 2024-00-00]
DOI Crossref
Semi-supervised Learning While Controlling the FDR with an Application to Tandem Mass Spectrometry Analysis
Freestone J, Käll L, Noble WS, Keich U
- - (-) 448-453 [2024-00-00; online 2024-05-17]
DOI Crossref
Privacy Protection in MRI Scans Using 3D Masked Autoencoders
Van der Goten LA, Smith K, the Alzheimer’s Disease Neuroimagin f
- - (-) 583-592 [2024-00-00; online 2024-10-03]
DOI Crossref
Optical Fiber-Based Module for Selection and Picking of Cells and Cell Clusters
Harish AV, Varela J, Gibbon T, ..., Russom A, Laurell F
EPJ Web Conf. 309 (-) 12007 [2024-00-00; online 2024-10-31]
DOI Crossref
Optical Fiber Based Cell Picking Module for Identification and Isolation of Single Cells or Clusters
Harish AV, Varela JC, Maniewski P, ..., Russom A, Laurell F
- - (-) ATh1B.2 [2024-00-00; online 2024-00-00]
DOI Crossref
Multi-Tissue Network Analysis Reveals the Effect of JNK Inhibition on Dietary Sucrose-Induced Metabolic Dysfunction in Rats
Yang H, Zhang C, Kim W, ..., Turkez H, Mardinoglu A
- - (-) - [2024-00-00; online 2024-00-00]
DOI Crossref
Integrative Proteo-Transcriptomic Characterization of Advanced Fibrosis in Chronic Liver Disease Across Etiologies
Yang H, Atak D, Yuan M, ..., Mardinoglu A, Zeybel M
- - (-) - [2024-00-00; online 2024-00-00]
DOI Crossref
Adaptive RESOLFT microscopy
Lin R, Testa I
- - (-) OW1F.1 [2024-00-00; online 2024-00-00]
SciLifeLab Data Centre
Publications 9.5.1