Publications 2024

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1422 publications

PubMed DOI Crossref
Life Science 2.0: reframing the life science sector for 'the benefit on mankind'.
Vallin M, Tomson G, Kampmann B, ..., Wanyenze RK, Ottersen OP
Glob Health Action 17 (1) 2330758 [2024-12-31; online 2024-04-05]
DOI Crossref
Can we infer excitation-inhibition balance from the spectrum of population activity?
Chakravarty K, Roy S, Sinha A, Kumar A
- - (-) - [2024-12-30; online 2024-12-30]
PubMed DOI Crossref
The FunCoup Cytoscape App: multi-species network analysis and visualization.
Buzzao D, Steininger L, Guala D, Sonnhammer ELL
Bioinformatics 41 (1) - [2024-12-26; online 2024-12-19]
PubMed DOI Crossref
Correction for Wärnberg and Kumar, Feasibility of dopamine as a vector-valued feedback signal in the basal ganglia.
Proc. Natl. Acad. Sci. U.S.A. 121 (52) e2424183121 [2024-12-24; online 2024-12-16]
PubMed DOI Crossref
VLDLR mediates Semliki Forest virus neuroinvasion through the blood-cerebrospinal fluid barrier.
Martikainen M, Lugano R, Pietilä I, ..., Dimberg A, Essand M
Nat Commun 15 (1) 10718 [2024-12-23; online 2024-12-23]
DOI Crossref
The Federated European Genome-phenome Archive as a global network for sharing human genomics data
Freeberg M, D'Altri T, Keane T, ..., Parkinson H, Navarro A
- - (-) - [2024-12-23; online 2024-12-23]
DOI Crossref
Evolutionary rescue of spherical mreB deletion mutants of the rod-shape bacterium Pseudomonas fluorescens SBW25
Yulo PRJ, Desprat N, Gerth ML, ..., Rainey PB, Hendrickson HL
- - (-) - [2024-12-23; online 2024-12-23]
PubMed DOI Crossref
Click chemistry-based dual nanosystem for microRNA-122 detection with single-base specificity from tumour cells.
Robles-Remacho A, Martos-Jamai I, Tabraue-Chávez M, ..., Diaz-Mochon JJ, Sanchez-Martin RM
J Nanobiotechnology 22 (1) 791 [2024-12-23; online 2024-12-23]
PubMed DOI Crossref
A Collection of Useful Nuisance Compounds (CONS) for Interrogation of Bioassay Integrity.
Hu H, Yi X, Xue L, Baell JB
JACS Au 4 (12) 4883-4891 [2024-12-23; online 2024-11-25]
DOI Crossref
HAPP: High-Accuracy Pipeline for Processing deep metabarcoding data
Sundh J, Granqvist E, Iwaszkiewicz-Eggebrecht E, ..., Andersson AF, Ronquist F
- - (-) - [2024-12-22; online 2024-12-22]
PubMed DOI Crossref
Microbial Dynamics: Assessing Skincare Regimens' Impact on the Facial Skin Microbiome and Skin Health Parameters.
Wagner N, Valeriano VD, Diou-Hirtz S, ..., Schuppe-Koistinen I, Gillbro JM
Microorganisms 12 (12) - [2024-12-21; online 2024-12-21]
DOI Crossref
GenePioneer: A Comprehensive Python Package for Identification of Essential Genes and Modules in Cancer
Taheri G, Haerianardakani A
- - (-) - [2024-12-21; online 2024-12-21]
DDLS Fellow Golnaz Taheri
DOI Crossref
Ex Vivo Drug Responses and Molecular Profiles of 597 Pediatric Acute Lymphoblastic Leukemia Patients
Enblad AP, Krali O, Gezelius H, ..., Lönnerholm G, Nordlund J
- - (-) - [2024-12-20; online 2024-12-20]
PubMed DOI Crossref
Biologically inspired bioactive hydrogels for scarless corneal repair.
Huang J, Jiang T, Qie J, ..., Yao K, Han H
Sci Adv 10 (51) eadt1643 [2024-12-20; online 2024-12-18]
DOI Crossref
A delivered DNase toxin creates population heterogeneity through transient intoxication of siblings
Eriksson H, Schlegel S, Kjellin J, Koskiniemi S
- - (-) - [2024-12-20; online 2024-12-20]
PubMed DOI Crossref
Unraveling the ancient fungal DNA from the Iceman gut.
Oskolkov N, Sandionigi A, Götherström A, ..., Buzzini P, Borruso L
BMC Genomics 25 (1) 1225 [2024-12-19; online 2024-12-19]
PubMed DOI Crossref
Molecular and functional profiling of primary normal ovarian cells defines insights into cancer development and drug responses.
Piki E, Dini A, Rantanen F, ..., Murumägi A, Ungureanu D
Mol Ther Oncol 32 (4) 200903 [2024-12-19; online 2024-11-08]
DOI Crossref
Crystallographic and NMR Study of Streptococcus pneumonia LCP Protein PsrSp Indicate the Importance of Dynamics in Four Long Loops for Ligand Specificity
Sandalova T, Sala BM, Moche M, ..., Agback P, Achour A
Crystals 14 (12) 1094 [2024-12-19; online 2024-12-19]
PubMed DOI Crossref
Treatment of Periprosthetic Joint Infection with Intravenous Vancomycin: Do We Hit the Target?
Haglund R, Tornberg U, Claesson AC, Freyhult E, Hailer NP
Antibiotics (Basel) 13 (12) - [2024-12-18; online 2024-12-18]
PubMed DOI Crossref
Paracentrotus lividus sea urchin gonadal extract mitigates neurotoxicity and inflammatory signaling in a rat model of Parkinson's disease.
Nagy NS, Helal M, Alsawy ES, ..., Al-Sherif SS, Essawy AE
PLoS ONE 19 (12) e0315858 [2024-12-18; online 2024-12-18]
DOI Crossref
ABHD2 activity is not required for the non-genomic action of progesterone on human sperm
Edwards M, Amaral A, Carter EM, ..., Gileadi O, Tredup C
- - (-) - [2024-12-18; online 2024-12-18]
DOI Crossref
Non-linear transcriptional responses to gradual modulation of transcription factor dosage
Domingo J, Minaeva M, Morris JA, ..., Sanjana NE, Lappalainen T
- - (-) - [2024-12-17; online 2024-12-17]
PubMed DOI Crossref
Flexible and robust cell type annotation for highly multiplexed tissue images.
Sun H, Yu S, Casals AM, ..., Lundberg E, Murphy RF
bioRxiv - (-) - [2024-12-17; online 2024-12-17]
PubMed DOI Crossref
Gaps between Open Science activities and actual recognition systems: Insights from an international survey.
Grattarola F, Shmagun H, Erdmann C, ..., Kim J, Mabile L
PLoS ONE 19 (12) e0315632 [2024-12-16; online 2024-12-16]
DOI Crossref
AI-first structural identification of pathogenic protein targets
Saluri M, Landreh M, Bryant P
- - (-) - [2024-12-16; online 2024-12-16]
DDLS Fellow Patrick Bryant
PubMed DOI Crossref
Author Correction: AutoTransOP: translating omics signatures without orthologue requirements using deep learning.
Meimetis N, Pullen KM, Zhu DY, ..., Magliacane S, Lauffenburger DA
NPJ Syst Biol Appl 10 (1) 148 [2024-12-13; online 2024-12-13]
Avlant Nilsson DDLS Fellow
PubMed DOI Crossref
Neuropilin-1 controls vascular permeability through juxtacrine regulation of endothelial adherens junctions.
Pal S, Su Y, Nwadozi E, Claesson-Welsh L, Richards M
Angiogenesis 28 (1) 7 [2024-12-12; online 2024-12-12]
PubMed DOI Crossref
How to build the virtual cell with artificial intelligence: Priorities and opportunities.
Bunne C, Roohani Y, Rosen Y, ..., Leskovec J, Quake SR
Cell 187 (25) 7045-7063 [2024-12-12; online 2024-12-14]
PubMed DOI Crossref
Complete genome sequences of the prosthecate dimorphic bacteria Brevundimonas intermedia CB63T and Brevundimonas staleyi FWC43T.
Hallgren J, Daneby F, Jonas K
Microbiol Resour Announc 13 (12) e0105024 [2024-12-12; online 2024-11-20]
Kristina Jonas SciLifeLab Fellow
DOI Crossref
ColBuilder: Flexible structure generation of crosslinked collagen fibrils
Monego D, Brosz M, Buck J, ..., Sugita Y, Gräter F
- - (-) - [2024-12-12; online 2024-12-12]
PubMed DOI Crossref
CSF levels of brain-derived proteins correlate with brain ventricular volume in cognitively healthy 70-year-olds.
Bergström S, Mravinacová S, Lindberg O, ..., Skoog I, Månberg A
Clin Proteomics 21 (1) 65 [2024-12-12; online 2024-12-12]
PubMed DOI Crossref
scTrends: A living review of commercial single-cell and spatial 'omic technologies.
De Jonghe J, Opzoomer JW, Vilas-Zornoza A, ..., Cribbs AP, Taylor-King JP
Cell Genom 4 (12) 100723 [2024-12-11; online 2024-12-13]
DOI Crossref
The Role of BAZ2-dependent Chromatin Remodeling in Suppressing G4 DNA Structures and Associated Genomic Instability
Vandeuren AL, O’Dare K, Wilson RHC, ..., Reed SH, Day TA
- - (-) - [2024-12-11; online 2024-12-11]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
EchoTilt: An Acoustofluidic Method for the Capture and Enrichment of Nanoplastics Directed Toward Drinking Water Monitoring.
Costa M, van der Geer L, Joaquim M, ..., Wiklund M, Russom A
Micromachines (Basel) 15 (12) - [2024-12-11; online 2024-12-11]
DOI Crossref
Activation of the ChvG-ChvI pathway promotes multiple survival strategies during cell wall stress in Agrobacterium tumefaciens
Bouchier JM, Knebel E, Amstutz J, ..., Cava F, Brown PJB
- - (-) - [2024-12-11; online 2024-12-11]
PubMed DOI Crossref
The impact of Parkinson's disease on striatal network connectivity and corticostriatal drive: An in silico study.
Carannante I, Scolamiero M, Hjorth JJJ, ..., Chachólski W, Kotaleski JH
Netw Neurosci 8 (4) 1149-1172 [2024-12-10; online 2024-12-10]
DOI Crossref
XRN1 supplies free nucleotides to feed alphavirus replication
Ruscica V, Iselin L, Hull R, ..., Davis I, Castello A
- - (-) - [2024-12-09; online 2024-12-09]
SciLifeLab Fellow
DOI Crossref
Pooled overexpression screening identifies PIPPI as a novel microprotein involved in the ER stress response
Lafranchi L, Spinner A, Hornisch M, ..., Piazza I, Elsässer SJ
- - (-) - [2024-12-09; online 2024-12-09]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Naturally acquired IgG responses to Plasmodium falciparum do not target the conserved termini of the malaria vaccine candidate Merozoite Surface Protein 2.
Zerebinski J, Margerie L, Han NS, ..., Färnert A, Plaza DF
Front Immunol 15 (-) 1501700 [2024-12-09; online 2024-12-09]
PubMed DOI Crossref
From early methods for DNA diagnostics to genomes and epigenomes at high resolution during four decades - a personal perspective.
Syvänen AC
Ups. J. Med. Sci. 129 (-) - [2024-12-09; online 2024-12-09]
PubMed DOI Crossref
Elucidating acquired PARP inhibitor resistance in advanced prostate cancer.
Seed G, Beije N, Yuan W, ..., Carreira S, de Bono J
Cancer Cell 42 (12) 2113-2123.e4 [2024-12-09; online 2024-11-21]
Arian Lundberg DDLS Fellow
PubMed DOI Crossref
Cell membranes sustain phospholipid imbalance via cholesterol asymmetry.
Doktorova M, Symons JL, Zhang X, ..., Levental KR, Levental I
bioRxiv - (-) - [2024-12-09; online 2024-12-09]
DDLS Fellow Erdinc Sezgin Milka Doktorova SciLifeLab Fellow
DOI Crossref
Plasma proteomics for novel biomarker discovery in childhood tuberculosis
Fossati A, Wambi P, Jaganath D, ..., Zar HJ, Swaney DL
- - (-) - [2024-12-08; online 2024-12-08]
Andrea Fossati DDLS Fellow
PubMed DOI Crossref
The Circulating Proteome─Technological Developments, Current Challenges, and Future Trends.
Geyer PE, Hornburg D, Pernemalm M, ..., Deutsch EW, Schwenk JM
J. Proteome Res. 23 (12) 5279-5295 [2024-12-06; online 2024-10-31]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
Saltational Episodes of Reticulate Evolution in the Drosophila saltans Species Group.
Prediger C, Ferreira EA, Zorzato SV, ..., Yassin A, Madi-Ravazzi L
Mol. Biol. Evol. 41 (12) - [2024-12-06; online 2024-12-11]
PubMed DOI Crossref
Coupling cellular drug-target engagement to downstream pharmacology with CeTEAM.
Valerie NCK, Sanjiv K, Mortusewicz O, ..., Page BDG, Altun M
Nat Commun 15 (1) 10347 [2024-12-06; online 2024-12-06]
PubMed DOI Crossref
"Head-to-Toe" Lipid Properties Govern the Binding and Cargo Transfer of High-Density Lipoprotein.
Weber F, Axmann M, Sezgin E, ..., Stangl H, Plochberger B
Membranes (Basel) 14 (12) - [2024-12-06; online 2024-12-06]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
SARS-CoV-2 N protein recruits G3BP to double membrane vesicles to promote translation of viral mRNAs.
Long S, Guzyk M, Perez Vidakovics L, ..., Achour A, McInerney GM
Nat Commun 15 (1) 10607 [2024-12-05; online 2024-12-05]
PubMed DOI Crossref
Multi-omics analysis detail a submicroscopic inv(15)(q14q15) generating fusion transcripts and MEIS2 and NUSAP1 haploinsufficiency.
Ek M, Kvarnung M, Pettersson M, ..., Eisfeldt J, Lindstrand A
Sci Rep 14 (1) 30343 [2024-12-05; online 2024-12-05]
PubMed DOI Crossref
Dynamics of the blood plasma proteome during hyperacute HIV-1 infection.
Nazziwa J, Freyhult E, Hong MG, ..., Hassan AS, Esbjörnsson J
Nat Commun 15 (1) 10593 [2024-12-05; online 2024-12-05]
PubMed DOI Crossref
A landscape of X-inactivation during human T cell development.
Gylemo B, Bensberg M, Hennings V, ..., Ekwall O, Nestor CE
Nat Commun 15 (1) 10527 [2024-12-04; online 2024-12-04]
Antonio Lentini DDLS Fellow
PubMed DOI Crossref
One-Pot Time-Induced Proteome Integral Solubility Alteration Assay for Automated and Sensitive Drug-Target Identification.
Meng Z, Saei AA, Lyu H, Gaetani M, Zubarev RA
Anal. Chem. 96 (48) 18917-18921 [2024-12-03; online 2024-11-20]
PubMed DOI Crossref
MTSS1: beyond the integration of actin and membrane dynamics.
Matskova L, Zheng S, Kashuba E, Ernberg I, Aspenström P
Cell. Mol. Life Sci. 81 (1) 472 [2024-12-03; online 2024-12-03]
PubMed DOI Crossref
Improved Localization of Insulinomas Using 68Ga-NODAGA-Exendin-4 PET/CT.
Boss M, Eriksson O, Mikkola K, ..., Hermans J, Gotthardt M
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 65 (12) 1959-1964 [2024-12-03; online 2024-12-03]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Identification of SPP1 + macrophages as an immune suppressor in hepatocellular carcinoma using single-cell and bulk transcriptomics.
Jin H, Kim W, Yuan M, ..., Zhang C, Mardinoglu A
Front Immunol 15 (-) 1446453 [2024-12-03; online 2024-12-03]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Correction: Candidate serum protein biomarkers for active pulmonary tuberculosis diagnosis in tuberculosis endemic settings.
Ayalew S, Wegayehu T, Wondale B, ..., Fredolini C, Mihret A
BMC Infect Dis 24 (1) 1380 [2024-12-03; online 2024-12-03]
PubMed DOI Crossref
The paradox of predictability provides a bridge between micro- and macroevolution.
Tsuboi M, Sztepanacz J, De Lisle S, ..., Love AC, Houle D
J Evol Biol 37 (12) 1413-1432 [2024-12-02; online 2024-08-31]
DDLS Fellow Lisandro Milocco
PubMed DOI Crossref
Spc2 modulates substrate- and cleavage site-selection in the yeast signal peptidase complex.
Chung Y, Yim C, Pereira GP, ..., Souza PCT, Kim H
J. Cell Biol. 223 (12) - [2024-12-02; online 2024-11-20]
PubMed DOI Crossref
PET imaging of GABAA receptors in pancreatic islets by [11C]flumazenil.
Maloum-Rami F, Cheung P, Antoni G, ..., Eriksson O, Espes D
EJNMMI Res 14 (1) 122 [2024-12-02; online 2024-12-02]
Daniel Espes Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Correction: Longitudinal assessment of reactivity and affinity profile of anti-Jo1 autoantibodies to distinct HisRS domains and a splice variant in a cohort of patients with myositis and anti-synthetase syndrome.
Notarnicola A, Preger C, Lundström SL, ..., Lundberg IE, Fernandes-Cerqueira C
Arthritis Res Ther 26 (1) 206 [2024-12-02; online 2024-12-02]
DOI Crossref
Advanced Peptide Nanoparticles Enable Robust and Efficient delivery of gene editors across cell types
Gustafsson O, Krishna S, Borate S, ..., Nordin JZ, Andaloussi SE
- - (-) - [2024-12-02; online 2024-12-02]
PubMed DOI Crossref
Characterising and preventing the gut microbiota's inactivation of trifluridine, a colorectal cancer drug.
McCoubrey LE, Shen C, Mwasambu S, ..., Globisch D, Basit AW
Eur J Pharm Sci 203 (-) 106922 [2024-12-01; online 2024-10-03]
Daniel Globisch SciLifeLab Fellow
DOI Crossref
Visual classification of tau‐PET detects four subtypes with different long‐term outcomes
Boccalini C, Mathoux G, Hristovska I, ..., Vogel JW, Garibotto V
Alzheimers Dement 20 (S9) - [2024-12-00; online 2025-01-09]
DOI Crossref
Visual classification of tau‐PET detects four subtypes with different long‐term outcomes
Boccalini C, Mathoux G, Hristovska I, ..., Vogel JW, Garibotto V
Alzheimers Dement 20 (S2) - [2024-12-00; online 2025-01-09]
DOI Crossref
Unlocking Tau PET Accessibility: a Machine Learning‐Based Prediction of Tau Pathology from Plasma, MRI and Clinical Variables
Karlsson L, Vogel JW, Strandberg O, ..., Mattsson‐Carlgren N, Hansson O
Alzheimers Dement 20 (S2) - [2024-12-00; online 2025-01-09]
PubMed DOI Crossref
Ultra-processed food consumption, plasma metabolite profile, and risk of all-cause and cause-specific mortality in a population-based cohort.
Du Y, Zhang S, Schjølberg JS, ..., Sonestedt E, Borné Y
Clin Nutr 43 (12) 184-193 [2024-12-00; online 2024-10-20]
PubMed DOI Crossref
Transport mechanism of DgoT, a bacterial homolog of SLC17 organic anion transporters.
Dmitrieva N, Gholami S, Alleva C, ..., Alfonso-Prieto M, Fahlke C
EMBO J. 43 (24) 6740-6765 [2024-12-00; online 2024-10-25]
DOI Crossref
The mTOR‐4E‐BP1 axis controls microglia inflammatory and neurodegenerative responses
Bermudez S, Choi J, Kim S, ..., Healy LM, Sonenberg N
Alzheimers Dement 20 (S1) - [2024-12-00; online 2025-01-03]
PubMed DOI Crossref
The last of their kind: Is the genus Scutiger (Anura: Megophryidae) a relict element of the paleo-Transhimalaya biota?
Hofmann S, Podsiadlowski L, Andermann T, ..., Jablonski D, Schmidt J
Mol. Phylogenet. Evol. 201 (-) 108166 [2024-12-00; online 2024-08-09]
DDLS Fellow Tobias Andermann
PubMed DOI Crossref
The evolutionary history of metastatic pancreatic neuroendocrine tumours reveals a therapy driven route to high-grade transformation.
Backman S, Botling J, Nord H, ..., Åkerström T, Crona J
J. Pathol. 264 (4) 357-370 [2024-12-00; online 2024-10-03]
DOI Crossref
The effect of basic body awareness therapy on awareness, stress and anxiety in pregnant women
Yüce H, Gökmen GY, Akçay B, Keçelioğlu Ş, Mart EM
Advances in Integrative Medicine 11 (4) 280-284 [2024-12-00; online 2024-12-00]
DOI Crossref
Targeting Alzheimer's disease with novel dual-function 3,5-diaryl-4,5-dihydro-1H-pyrazole-1-carbothioamide derivatives
Katsogiannou A, Karta D, Di Stefano A, ..., Vassiliou S, Cacciatore I
European Journal of Medicinal Chemistry Reports 12 (-) 100235 [2024-12-00; online 2024-12-00]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Structural basis of LRPPRC-SLIRP-dependent translation by the mitoribosome.
Singh V, Moran JC, Itoh Y, ..., Barrientos A, Amunts A
Nat. Struct. Mol. Biol. 31 (12) 1838-1847 [2024-12-00; online 2024-08-12]
Alexey Amunts SciLifeLab Fellow
PubMed DOI Crossref
Single-molecule states link transcription factor binding to gene expression.
Doughty BR, Hinks MM, Schaepe JM, ..., Bintu L, Greenleaf WJ
Nature 636 (8043) 745-754 [2024-12-00; online 2024-11-20]
Emil Marklund SciLifeLab Fellow
PubMed DOI Crossref
SenNet recommendations for detecting senescent cells in different tissues.
Suryadevara V, Hudgins AD, Rajesh A, ..., Dou Z, Neretti N
Nat. Rev. Mol. Cell Biol. 25 (12) 1001-1023 [2024-12-00; online 2024-06-03]
Sanja Vickovic SciLifeLab Fellow
PubMed DOI Crossref
Scifer: An R/Bioconductor package for large-scale integration of Sanger sequencing and flow cytometry data of index-sorted single cells.
Cerveira RA, Lenart K, Martin M, ..., Ols S, Loré K
ImmunoInformatics 16 (-) 100046 [2024-12-00; online 2024-10-29]
PubMed DOI Crossref
Role of human plasma metabolites in prediabetes and type 2 diabetes from the IMI-DIRECT study.
Sharma S, Dong Q, Haid M, ..., Pearson ER, Grallert H
Diabetologia 67 (12) 2804-2818 [2024-12-00; online 2024-09-30]
PubMed DOI Crossref
Risk factors for Charcot foot development in individuals with diabetes mellitus.
Tsatsaris G, Rajamand Ekberg N, Fall T, Catrina SB
Diabetologia 67 (12) 2702-2710 [2024-12-00; online 2024-09-13]
PubMed DOI Crossref
Reviewability and supportability: New complementary principles to empower research software practices.
Zhang H, Maillo A, Khan SA, ..., Gomez-Cabrero D, Tegnér J
Comput Struct Biotechnol J 23 (-) 3989-3998 [2024-12-00; online 2024-11-06]
DOI Crossref
Regional Amyloid Load Predicts Tau and Atrophy Dynamics
Chaggar P, Vogel JW, Binette AP, ..., Hansson O, Goriely A
Alzheimers Dement 20 (S2) - [2024-12-00; online 2025-01-09]
DOI Crossref
Proteomics analysis characterizing new markers related to Aβ plaques and tau tangles pathologies
Binette AP, Wennström M, Strandberg O, ..., Vogel JW, Hansson O
Alzheimers Dement 20 (S2) - [2024-12-00; online 2025-01-09]
PubMed DOI Crossref
Probe set selection for targeted spatial transcriptomics.
Kuemmerle LB, Luecken MD, Firsova AB, ..., Samakovlis C, Theis FJ
Nat. Methods 21 (12) 2260-2270 [2024-12-00; online 2024-11-18]
PubMed DOI Crossref
Preferences and attitudes regarding early intervention in multiple sclerosis: A systematic literature review.
Martin S, Kihlbom U, Pasquini G, ..., Aloni R, Schölin Bywall K
Mult Scler Relat Disord 92 (-) 106143 [2024-12-00; online 2024-10-28]
PubMed DOI Crossref
Orthopteran Neo-Sex Chromosomes Reveal Dynamics of Recombination Suppression and Evolution of Supergenes.
Jayaprasad S, Peona V, Ellerstrand SJ, ..., Schielzeth H, Palacios-Gimenez OM
Mol. Ecol. 33 (23) e17567 [2024-12-00; online 2024-10-30]
PubMed DOI Crossref
Optimising in-cell NMR acquisition for nucleic acids.
Annecke HTP, Eidelpes R, Feyrer H, ..., Dasgupta R, Petzold K
J Biomol NMR 78 (4) 249-264 [2024-12-00; online 2024-08-20]
PubMed DOI Crossref
Novel tetrahydronaphthalen-1-yl-phenethyl ureas: synthesis and dual antibacterial-anticancer activities.
Akbaba Y, Kacı FN, Arslan ME, ..., Mardinoğlu A, Türkez H
J Enzyme Inhib Med Chem 39 (1) 2286925 [2024-12-00; online 2023-12-07]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
No association between celiac disease and female infertility: evidence from Mendelian randomization analysis.
Yuan S, Chen J, Li X, ..., Larsson SC, Ludvigsson JF
Fertil. Steril. 122 (6) 1144-1146 [2024-12-00; online 2024-07-06]
PubMed DOI Crossref
New developments for the Quest for Orthologs benchmark service.
Altenhoff A, Nevers Y, Tran V, ..., Ebersberger I, Sonnhammer E
NAR Genomics and Bioinformatics 6 (4) lqae167 [2024-12-00; online 2024-12-11]
DDLS Fellow Sina Majidian
DOI Crossref
Multiplex detection of meningitis pathogens by a vertical flow paper microarray and signal enhancement suitable for low-resource settings: Proof of concept
Réu P, Gaudenzi G, Nanjebe D, ..., Boum II Y, Russom A
Talanta Open 10 (-) 100357 [2024-12-00; online 2024-12-00]
DOI Crossref
Individual variation in proteomic cascades along the Alzheimer’s disease spectrum
Vogel JW, Vilkaite G, Binette AP, ..., Mattsson‐Carlgren N, Hansson O
Alzheimers Dement 20 (S2) - [2024-12-00; online 2025-01-09]
DOI Crossref
Improved precision of Alzheimer’s disease fluid biomarkers when using Amyloid‐β40 or non‐phosphorylated tau as a reference
Karlsson L, Janelidze S, Horie K, ..., Mattsson‐Carlgren N, Hansson O
Alzheimers Dement 20 (S2) - [2024-12-00; online 2025-01-09]
DOI Crossref
Impact of regional MAPT, APOE, and Aβ on tau propagation in Alzheimer’s disease: Insights from a connectome‐based simulation model
Xiao Y, Strandberg O, Bazinet V, ..., Hansson O, Vogel JW
Alzheimers Dement 20 (S8) - [2024-12-00; online 2025-01-09]
PubMed DOI Crossref
Exploratory insights from the immuno-oncology hollow fiber assay: A pilot approach bridging In Vitro and In Vivo models.
Selvin T, Berglund M, Åkerström A, ..., Andersson CR, Fryknäs M
SLAS Technol 29 (6) 100232 [2024-12-00; online 2024-12-03]
PubMed DOI Crossref
Emerging mutation in SARS-CoV-2 facilitates escape from NK cell recognition and associates with enhanced viral fitness.
Bilev E, Wild N, Momayyezi P, ..., Achour A, Hammer Q
PLoS Pathog 20 (12) e1012755 [2024-12-00; online 2024-12-09]
PubMed DOI Crossref
Effect of an endothelial regulatory module on plasma proteomics in exercising horses.
Amiri Roudbar M, Rosengren MK, Mousavi SF, ..., Meadows JRS, Lindgren G
Comp Biochem Physiol Part D Genomics Proteomics 52 (-) 101265 [2024-12-00; online 2024-06-06]
PubMed DOI Crossref
Early detection of pancreatic cancer: Study design and analytical considerations in biomarker discovery and early phase validation studies.
Smith LM, Mahoney DW, Bamlet WR, ..., Koay EJ, Oberg AL
Pancreatology 24 (8) 1265-1279 [2024-12-00; online 2024-10-29]
DDLS Fellow Qiaoli Wang
PubMed DOI Crossref
Diagnosing Monogenic Stroke at Younger Age.
Ilinca A, Kafantari E, Wallenius J, ..., Puschmann A, Lindgren AG
Stroke 55 (12) 2846-2855 [2024-12-00; online 2024-11-05]
DOI Crossref
Designing from biobased to closed-loop circularity: Flexible dynamic polyimine-amide networks
Subramaniyan S, Zhang B, Syrén PO, Hakkarainen M
Chem Eng J 501 (-) 157632 [2024-12-00; online 2024-12-00]
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Data‐driven progression patterns of Aβ, tau, α‐synuclein and vascular pathology in a clinical population
Mastenbroek SE, Collij LE, Vogel JW, ..., Ossenkoppele R, Hansson O
Alzheimers Dement 20 (S9) - [2024-12-00; online 2025-01-09]
DOI Crossref
Data‐driven progression patterns of Aβ, tau, α‐synuclein and vascular pathology in a clinical population
Mastenbroek SE, Collij LE, Vogel JW, ..., Ossenkoppele R, Hansson O
Alzheimers Dement 20 (S2) - [2024-12-00; online 2025-01-09]
PubMed DOI Crossref
Cyclophilin D plays a critical role in the survival of senescent cells.
Protasoni M, López-Polo V, Stephan-Otto Attolini C, ..., Kovatcheva M, Serrano M
EMBO J. 43 (23) 5972-6000 [2024-12-00; online 2024-10-24]
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CopyMix: Mixture model based single-cell clustering and copy number profiling using variational inference.
Safinianaini N, De Souza CPE, Roth A, ..., Toosi H, Lagergren J
Comput Biol Chem 113 (-) 108257 [2024-12-00; online 2024-10-23]
PubMed DOI Crossref
Congenital Hypothyroidism and School Achievement in Adolescence: A Population-Based Sibling Control Study.
Gunnerbeck A, Lundholm C, von Döbeln U, ..., Almqvist C, Nordenström A
J Pediatr 275 (-) 114240 [2024-12-00; online 2024-08-14]
DOI Crossref
Blood‐based biomarkers of Alzheimer’s disease and 15‐year rate of olfactory decline in an elderly population
Ekström I, Vetrano DL, Ruane R, ..., Fratiglioni L, Laukka EJ
Alzheimers Dement 20 (S2) - [2024-12-00; online 2025-01-09]
DOI Crossref
Benzylhydroxamic acids as inhibitors of insulin regulated aminopeptidase (IRAP)
Beveridge J, Söderström M, Prieto-Díaz R, ..., Larhed M, Gising J
European Journal of Medicinal Chemistry Reports 12 (-) 100215 [2024-12-00; online 2024-12-00]
PubMed DOI Crossref
Autoantibodies against a subunit of mitochondrial respiratory chain complex I in inclusion body myositis.
Notarnicola A, Hellstrom C, Horuluoglu B, ..., Nilsson P, Lundberg IE
J. Autoimmun. 149 (-) 103332 [2024-12-00; online 2024-11-18]
PubMed DOI Crossref
Author Correction: A virally encoded tRNA neutralizes the PARIS antiviral defence system.
Burman N, Belukhina S, Depardieu F, ..., Wiedenheft B, Isaev A
Nature 636 (8043) E8 [2024-12-00; online 2024-12-05]
DOI Crossref
Associations between blood‐based biomarkers of Alzheimer’s disease and rate of global and domain‐specific cognitive decline in an elderly population with 15 years of follow‐up
Laukka EJ, Ekström I, Grande G, ..., Fratiglioni L, Vetrano DL
Alzheimers Dement 20 (S3) - [2024-12-00; online 2025-01-03]
PubMed DOI Crossref
A transcriptome atlas of zygotic and somatic embryogenesis in Norway spruce.
Stojkovič K, Canovi C, Le KC, ..., Egertsdotter U, Street NR
Plant J. 120 (5) 2238-2252 [2024-12-00; online 2024-10-27]
PubMed DOI Crossref
A framework for sharing of clinical and genetic data for precision medicine applications.
Elhussein A, Baymuradov U, NYGC ALS Consortium , ..., Natarajan K, Gürsoy G
Nat. Med. 30 (12) 3578-3589 [2024-12-00; online 2024-09-03]
PubMed DOI Crossref
Spatial profiling of the mouse colonic immune landscape associated with colitis and sex.
Holm M, Stepanauskaitė L, Bäckström A, ..., Stadler C, Williams C
Commun Biol 7 (1) 1595 [2024-11-29; online 2024-11-29]
DOI Crossref
Deteriorated mechanics of left ventricular diastolic filling one year after coronary artery bypass grafting
Norderfeldt J, Sundqvist MG, Maret E, ..., Eriksson MJ, Ugander M
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PubMed DOI Crossref
Aquaporin-4 as a cerebrospinal fluid biomarker of Alzheimer's disease.
Gómez de San José N, Halbgebauer S, Steinacker P, ..., Parnetti L, Otto M
Transl Neurodegener 13 (1) 57 [2024-11-29; online 2024-11-29]
PubMed DOI Crossref
The ROCK-1/2 inhibitor RKI-1447 blocks N-MYC, promotes cell death, and emerges as a synergistic partner for BET inhibitors in neuroblastoma.
Pepich A, Tümmler C, Abu Ajamieh S, ..., Johnsen JI, Wickström M
Cancer Lett. 605 (-) 217261 [2024-11-28; online 2024-09-20]
PubMed DOI Crossref
Sparse Neighbor Joining: rapid phylogenetic inference using a sparse distance matrix.
Kurt S, Bouchard-Côté A, Lagergren J
Bioinformatics 40 (12) - [2024-11-28; online 2024-11-21]
PubMed DOI Crossref
Author Correction: Integration of whole-body [18F]FDG PET/MRI with non-targeted metabolomics can provide new insights on tissue-specific insulin resistance in type 2 diabetes.
Diamanti K, Visvanathar R, Pereira MJ, ..., Wadelius C, Ahlström H
Sci Rep 14 (1) 29632 [2024-11-28; online 2024-11-28]
PubMed DOI Crossref
A Swedish dietary guideline index, gut microbial α-diversity and prevalence of metabolic syndrome - observations in the Swedish CArdioPulmonary bioImage Study (SCAPIS).
Ericson U, Hellstrand S, Larsson A, ..., Fall T, Orho-Melander M
Food Nutr Res 68 (-) - [2024-11-28; online 2024-11-28]
PubMed DOI Crossref
Maintenance of cell wall remodeling and vesicle production are connected in Mycobacterium tuberculosis.
Salgueiro V, Bertol J, Gutierrez C, ..., Sanz J, Prados-Rosales R
bioRxiv - (-) - [2024-11-27; online 2024-11-27]
PubMed DOI Crossref
Cryo-EM structure of single-layered nucleoprotein-RNA complex from Marburg virus.
Zinzula L, Beck F, Camasta M, ..., Plitzko JM, Baumeister W
Nat Commun 15 (1) 10307 [2024-11-27; online 2024-11-27]
PubMed DOI Crossref
Contemporary menopausal hormone therapy and risk of cardiovascular disease: Swedish nationwide register based emulated target trial.
Johansson T, Karlsson T, Bliuc D, ..., Center JR, Johansson Å
BMJ 387 (-) e078784 [2024-11-27; online 2024-11-27]
DOI Crossref
Recommendations for Bioinformatics in Clinical Practice
Lavrichenko K, Engdal ES, Marvig RL, ..., Wirta V, Bagger FO
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PubMed DOI Crossref
The association between novel urinary kidney damage biomarkers and coronary atherosclerosis in an apparently healthy population.
Lin YT, Wuopio J, Larsson A, ..., Fall T, Ärnlöv J
Sci Rep 14 (1) 29215 [2024-11-25; online 2024-11-25]
PubMed DOI Crossref
Streptolysin O accelerates the conversion of plasminogen to plasmin.
Tang D, Khakzad H, Hjortswang E, ..., Happonen L, Malmström J
Nat Commun 15 (1) 10212 [2024-11-25; online 2024-11-25]
DOI Crossref
Microneedles loaded with lipid nanocarriers for local treatment of vulvovaginal candidiasis
Udayakumar P, Škalko-Basnet N, Salas Cotaquispe CF, ..., Du J, Teleki A
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Alexandra Teleki SciLifeLab Fellow
PubMed DOI Crossref
Co-occurring mutations identify prognostic subgroups of microsatellite stable colorectal cancer.
Nunes L, Stenersen JM, Kryeziu K, ..., Lothe RA, Sveen A
Mol Cancer 23 (1) 264 [2024-11-25; online 2024-11-25]
PubMed DOI Crossref
Naltrexone blocks alcohol-induced effects on kappa-opioid receptors in the plasma membrane.
Oasa S, Sezgin E, Ma Y, ..., Vukojević V, Terenius L
Transl Psychiatry 14 (1) 477 [2024-11-24; online 2024-11-24]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
The early transcriptional and post-transcriptional responses to fluconazole in sensitive and resistant Candida albicans.
Stevens I, Silao FG, Huch S, ..., Ljungdahl PO, Pelechano V
Sci Rep 14 (1) 29012 [2024-11-22; online 2024-11-22]
SciLifeLab Fellow
PubMed DOI Crossref
Response to Letter to Editor by A. Derbalah et al.: the role of automation in enhancing reproducibility and interoperability of PBPK models.
Domínguez-Romero E, Mazurenko S, Scheringer M, ..., Županič A, Suarez-Diez M
Brief. Bioinformatics 26 (1) - [2024-11-22; online 2025-02-10]
PubMed DOI Crossref
Bridging the gap: Integrating cutting-edge techniques into biological imaging with deepImageJ.
Fuster-Barceló C, García-López-de-Haro C, Gómez-de-Mariscal E, ..., Sage D, Muñoz-Barrutia A
Biol Imaging 4 (-) e14 [2024-11-22; online 2024-11-22]
DDLS Fellow Wei Ouyang
DOI Crossref
Unravelling the molecular activation of the reparative cardiac fibroblasts after myocardial infarction
Hernández SC, Ainciburu M, Sudupe L, ..., Ruiz-Villalba A, Gómez-Cabrero D
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PubMed DOI Crossref
Flipping a switch on BRD4: How to control the do-it-all.
van Hout FAH, Vihervaara A
Mol. Cell 84 (22) 4257-4259 [2024-11-21; online 2024-11-23]
Anniina Vihervaara SciLifeLab Fellow
PubMed DOI Crossref
Candidate serum protein biomarkers for active pulmonary tuberculosis diagnosis in tuberculosis endemic settings.
Ayalew S, Wegayehu T, Wondale B, ..., Fredolini C, Mihret A
BMC Infect Dis 24 (1) 1329 [2024-11-21; online 2024-11-21]
PubMed DOI Crossref
Visualization and analysis of medically relevant tandem repeats in nanopore sequencing of control cohorts with pathSTR.
De Coster W, Höijer I, Bruggeman I, ..., Ameur A, Rademakers R
Genome Res 34 (11) 2074-2080 [2024-11-20; online 2024-11-20]
PubMed DOI Crossref
SARS-CoV-2 and HSV-1 Induce Amyloid Aggregation in Human CSF Resulting in Drastic Soluble Protein Depletion.
Christ W, Kapell S, Sobkowiak MJ, ..., El Andaloussi S, Ezzat K
ACS Chem Neurosci 15 (22) 4095-4104 [2024-11-20; online 2024-11-07]
PubMed DOI Crossref
Resolving complex duplication variants in autism spectrum disorder using long-read genome sequencing.
Eisfeldt J, Higginbotham EJ, Lenner F, ..., Scherer SW, Feuk L
Genome Res 34 (11) 1763-1773 [2024-11-20; online 2024-11-20]
PubMed DOI Crossref
Leveraging the T2T assembly to resolve rare and pathogenic inversions in reference genome gaps.
Bilgrav Saether K, Eisfeldt J, Bengtsson JD, ..., Carvalho CMB, Lindstrand A
Genome Res 34 (11) 1785-1797 [2024-11-20; online 2024-11-20]
PubMed DOI Crossref
A national long-read sequencing study on chromosomal rearrangements uncovers hidden complexities.
Eisfeldt J, Ameur A, Lenner F, ..., Feuk L, Lindstrand A
Genome Res 34 (11) 1774-1784 [2024-11-20; online 2024-11-20]
DOI Crossref
A Phylogenomic Analysis of Genipa (Rubiaceae) Using Target Sequence Capture Data
Ridley R, Persson C, Oxelman B, Andermann T, Bacon CD
Systematic Botany 49 (3) 617-625 [2024-11-19; online 2024-11-19]
DDLS Fellow Tobias Andermann
PubMed DOI Crossref
The Role of Water Networks in Phosphodiesterase Inhibitor Dissociation and Kinetic Selectivity.
Blaazer AR, Singh AK, Zara L, ..., Brown DG, de Esch IJP
ChemMedChem 19 (22) e202400417 [2024-11-18; online 2024-09-12]
DOI Crossref
Host-specific adaptation of Legionella pneumophila to single and multiple hosts
Moreno AB, Paranjape K, Cederblom M, ..., Andersson DI, Guy L
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PubMed DOI Crossref
Enterotoxigenic Escherichia coli in Blantyre, Malawi.
Ashton PM, Katuah ZJ, Botomani A, ..., Msefula C, Jere KC
Access Microbiol 6 (11) - [2024-11-18; online 2024-11-18]
Astrid von Mentzer DDLS Fellow
PubMed DOI Crossref
Cooperative role of LSD1 and CHD7 in regulating differentiation of mouse embryonic stem cells.
Malla S, Martinez-Gamero C, Kumari K, ..., Roman AC, Aguilo F
Sci Rep 14 (1) 28495 [2024-11-18; online 2024-11-18]
PubMed DOI Crossref
Arthritis progressors have a decreased frequency of circulating autoreactive T cells during the at-risk phase of rheumatoid arthritis.
Turcinov S, Sharma RK, De Vries C, ..., Malmström V, Hensvold A
RMD Open 10 (4) - [2024-11-18; online 2024-11-18]
PubMed DOI Crossref
A dispensable SepIVA orthologue in Streptomyces venezuelae is associated with polar growth and not cell division.
Sen BC, Mavi PS, Irazoki O, ..., Cava F, Flärdh K
BMC Microbiol. 24 (1) 481 [2024-11-18; online 2024-11-18]
PubMed DOI Crossref
tRNA regulation and amino acid usage bias reflect a coordinated metabolic adaptation in Plasmodium falciparum.
Li Q, Vetter L, Veith Y, ..., Larsson O, Chun-Leung Chan S
iScience 27 (11) 111167 [2024-11-15; online 2024-10-12]
PubMed DOI Crossref
Design, synthesis, and in vitro biological evaluation of meta-sulfonamidobenzamide-based antibacterial LpxH inhibitors.
Benediktsdottir A, Sooriyaarachchi S, Cao S, ..., Sandström A, Karlén A
Eur J Med Chem 278 (-) 116790 [2024-11-15; online 2024-08-22]
PubMed DOI Crossref
A comparative analysis of blastoid models through single-cell transcriptomics.
Balubaid A, Alsolami S, Kiani NA, ..., Li M, Tegner J
iScience 27 (11) 111122 [2024-11-15; online 2024-10-11]
DOI Crossref
Sox9 and Nfi transcription factors regulate the timing of neurogenesis and ependymal maturation in dopamine progenitors
Lahti L, Volakakis N, Gillberg L, ..., Gronostajski R, Perlmann T
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PubMed DOI Crossref
Passive immunization of mice with IgY anti-H5N1 protects against experimental influenza virus infection and allows development of protective immunity.
Eriksson M, Nylén S, Grönvik KO
Vaccine 42 (25) 126133 [2024-11-14; online 2024-07-16]
PubMed DOI Crossref
JAK2-mutant clonal hematopoiesis is associated with venous thromboembolism.
Zon RL, Sekar A, Clapham K, ..., Natarajan P, Ebert BL
Blood 144 (20) 2149-2154 [2024-11-14; online 2024-08-05]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
From Virtual Screens to Cellular Target Engagement: New Small Molecule Ligands for the Immune Checkpoint LAG-3.
Fuchs N, Calvo-Barreiro L, Talagayev V, ..., Wolber G, Gabr MT
ACS Med. Chem. Lett. 15 (11) 1884-1890 [2024-11-14; online 2024-10-15]
PubMed DOI Crossref
Colchicine prevents accelerated atherosclerosis in TET2-mutant clonal haematopoiesis.
Zuriaga MA, Yu Z, Matesanz N, ..., Natarajan P, Fuster JJ
Eur. Heart J. 45 (43) 4601-4615 [2024-11-14; online 2024-09-01]
Abhishek Niroula DDLS Fellow
DOI Crossref
Abstract PR002: Hypoxia-induced epigenetic changes coordinate transcription start site selection and translational control through remodeling of 5’UTRs
Watt K, Dauber B, Szkop KJ, ..., Larsson O, Postovit LM
Mol. Cancer Ther. 23 (11_Supplement) PR002-PR002 [2024-11-14; online 2024-11-14]
PubMed DOI Crossref
Tertiary Lymphoid Structures in Central Nervous System Disorders.
Vaccaro A, de Alves Pereira B, van de Walle T, Dimberg A
Methods in molecular biology (Clifton, N.J.) 2864 (-) 21-42 [2024-11-13; online 2024-11-13]
PubMed DOI Crossref
Prospective Screening of Cancer Syndromes in Patients with Mesenchymal Tumors.
Öfverholm I, Lin Y, Mondini J, ..., Haglund de Flon F, Wallander K
Cancers (Basel) 16 (22) - [2024-11-13; online 2024-11-13]
DOI Crossref
Diagnosing the role of atmospheric variability on the extreme summer monsoon precipitation events over India
kaagita V, Thandlam V, Sakirevu Palli VR, Muriki SK, Mathew M
Discov Atmos 2 (1) - [2024-11-13; online 2024-11-13]
PubMed DOI Crossref
Simultaneous detection of membrane contact dynamics and associated Ca2+ signals by reversible chemogenetic reporters.
García Casas P, Rossini M, Påvénius L, ..., Pizzo P, Filadi R
Nat Commun 15 (1) 9775 [2024-11-12; online 2024-11-12]
PubMed DOI Crossref
Annotated genome sequences of Salmonella Haifa, Salmonella Bangkok, and Salmonella Reading, isolated from chicken meat in South Africa.
Mathole M, Carroll L, Khabo-Mmekoa C, Mabogoane N, Matle I
Microbiol Resour Announc 13 (11) e0028424 [2024-11-12; online 2024-10-09]
DDLS Fellow Laura Carroll
PubMed DOI Crossref
Single cell long read whole genome sequencing reveals somatic transposon activity in human brain.
Izydorczyk MB, Kalef-Ezra E, Horner DW, ..., Sedlazeck FJ, Proukakis C
medRxiv - (-) - [2024-11-11; online 2024-11-11]
DOI Crossref
Comprehensive multi-omics profiling of a healthy human cohort
de Visser C, Niehues A, Najdekr L, ..., Hajdúch M, Hoen PAC’
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CNSC-11. INVESTIGATION OF GLIOBLASTOMA NEURON-TUMOR NETWORKS WITH RABIES-BASED RETROGRADE TRACING
Tetzlaff SK, Reyhan E, Bengtson CP, ..., Saez-Rodriguez J, Venkataramani V
Neuro-oncology 26 (Supplement_8) viii42-viii42 [2024-11-11; online 2024-11-11]
PubMed DOI Crossref
A genome resource for the marine annelid Platynereis dumerilii.
Mutemi KN, Simakov O, Pan L, ..., Özpolat BD, Arendt D
bioRxiv - (-) - [2024-11-11; online 2024-11-11]
PubMed DOI Crossref
Patient-derived organoids in precision cancer medicine.
Tong L, Cui W, Zhang B, ..., Si L, Lundqvist A
Med 5 (11) 1351-1377 [2024-11-08; online 2024-09-27]
PubMed DOI Crossref
Multisystem health comorbidity networks of metabolic dysfunction-associated steatotic liver disease.
Jiang F, Wang L, Ying H, ..., Ding Y, Li X
Med 5 (11) 1413-1423.e3 [2024-11-08; online 2024-08-07]
PubMed DOI Crossref
Latent space arithmetic on data embeddings from healthy multi-tissue human RNA-seq decodes disease modules.
de Weerd HA, Guala D, Gustafsson M, ..., Lubovac-Pilav Z, Magnusson R
Patterns (N Y) 5 (11) 101093 [2024-11-08; online 2024-10-31]
PubMed DOI Crossref
Inhibition of IRAP Enhances the Expression of Pro-Cognitive Markers Drebrin and MAP2 in Rat Primary Neuronal Cells.
Stam F, Bjurling S, Nylander E, ..., Grönbladh A, Hallberg M
Int J Mol Sci 25 (22) - [2024-11-08; online 2024-11-08]
PubMed DOI Crossref
AlphaFold with conformational sampling reveals the structural landscape of homorepeats.
Bonet DF, Ranyai S, Aswad L, ..., Landreh M, Lama D
Structure 32 (11) 2160-2167.e2 [2024-11-07; online 2024-09-18]
PubMed DOI Crossref
Unraveling the Bivalent and Rapid Interactions Between a Multivalent RNA Recognition Motif and RNA: A Kinetic Approach.
Pérez-Ropero G, Pérez-Ràfols A, Martelli T, Danielson UH, Buijs J
Biochemistry 63 (21) 2816-2829 [2024-11-05; online 2024-10-14]
PubMed DOI Crossref
Three-dimensional localization and tracking of chromosomal loci throughout the Escherichia coli cell cycle.
Karempudi P, Gras K, Amselem E, ..., Schirman D, Elf J
Commun Biol 7 (1) 1443 [2024-11-05; online 2024-11-05]
DOI Crossref
Targeting the SWI/SNF Chromatin Remodeling Complex Subunit SMARCA4 in ALL
Ayyadevara VSSA, Paik A, Perencsik R, ..., Geng H, Hurtz C
Blood 144 (Supplement 1) 4216-4216 [2024-11-05; online 2024-11-05]
PubMed DOI Crossref
Standalone single- and bi-layered human skin 3D models supported by recombinant silk feature native spatial organization.
Gkouma S, Bhalla N, Frapard S, ..., Widhe M, Hedhammar M
Biofabrication 17 (1) - [2024-11-05; online 2024-11-05]
DOI Crossref
Resistance to FLT3 Inhibitors in FLT3-Mutated AML Is Associated with CD45RA+CD200- leukemic Cells and Can be Overcome By Combination with SMAC Mimetics
Struyf N, Gezelius H, Lundmark A, ..., Kallioniemi O, Erkers T
Blood 144 (Supplement 1) 1565-1565 [2024-11-05; online 2024-11-05]
DOI Crossref
Plasma Proteomics Differentiates between Patients with B-Cell Lymphomas
Babačić H, Chowdhury NM, Berglund M, ..., Pernemalm M, Hellström M
Blood 144 (Supplement 1) 4370-4370 [2024-11-05; online 2024-11-05]
PubMed DOI Crossref
On the Versatility of the sp-, sp 2-, and sp 3-Hybridized Chalcogen-Bearing Molecules To Engage in Type I Chalcogen···Chalcogen Interactions: A Quantum Mechanical Investigation of Like···Like and Unlike Complexes.
Ibrahim MAA, Saeed RRA, Shehata MNI, ..., El-Tayeb MA, Shoeib T
ACS Omega 9 (44) 44448-44456 [2024-11-05; online 2024-10-23]
DOI Crossref
Mutations in BCORCCND2NRAS and XPO1 Predict Clinical Outcomes upon MRD-Guided Venetoclax Plus Ibrutinib in Relapsed and Refractory Chronic Lymphocytic Leukemia
Brieghel C, Dubois J, Buhl IK, ..., Kater AP, Niemann CU
Blood 144 (Supplement 1) 586-586 [2024-11-05; online 2024-11-05]
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Mutation-Specific Differences in the Relationship between Obesity and Clonal Hematopoiesis, with a Focus on JAK2V617F and MPN Prevention
Rolles B, Sekar A, Serrano-Ron L, ..., Hormoz S, Mullally A
Blood 144 (Supplement 1) 872-872 [2024-11-05; online 2024-11-05]
DOI Crossref
Mapping the Spatial Proteome of Individual Leukemia Cells Undergoing Fludarabine Treatment
Nordlund J, Globisch M, Gezelius H, ..., Raine A, Andersson C
Blood 144 (Supplement 1) 2212-2212 [2024-11-05; online 2024-11-05]
DOI Crossref
Differential Response to ATR/Chk1 Inhibition in Preleukemia and Transformed Leukemia in an MLL-ENL Model of Leukemogenesis Reflects Enrichment for Myc-Transcriptional Program
Chaloupkova P, Janotka L, Gursky J, ..., Bartek J, Divoky V
Blood 144 (Supplement 1) 5725-5725 [2024-11-05; online 2024-11-05]
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Deciphering the Heterogeneity of Acute Myeloid Leukemia through Chromatin Accessibility Profiling
Ochi Y, Liew-Littorin M, Nannya Y, ..., Lehmann S, Ogawa S
Blood 144 (Supplement 1) 639-639 [2024-11-05; online 2024-11-05]
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Clinical Relevance of the Integrative Analysis of Gut Microbiome and Metabolomics in Myeloid Neoplasms: Correlations with Genomic Profiles, Treatment Response/Complications and Clinical Outcome
Campagna A, Clasen F, Portlock T, ..., Della Porta MG, Shoaie S
Blood 144 (Supplement 1) 104-104 [2024-11-05; online 2024-11-05]
Saeed Shoaie SciLifeLab Fellow
PubMed DOI Crossref
CCDC28A deficiency causes head-tail coupling defects and immotility in murine spermatozoa.
Stojanovic N, Hernández RO, Ramírez NT, ..., Hernández AH, Shibuya H
Sci Rep 14 (1) 26808 [2024-11-05; online 2024-11-05]
PubMed DOI Crossref
BMI trajectories from birth to young adulthood associate with distinct cardiometabolic profiles.
Wang G, Wei D, Kebede Merid S, ..., Bergström A, Melén E
BMC Med 22 (1) 510 [2024-11-05; online 2024-11-05]
PubMed DOI Crossref
A bispecific CD40 agonistic antibody allowing for antibody-peptide conjugate formation to enable cancer-specific peptide delivery, resulting in improved T proliferation and anti-tumor immunity in mice.
Mebrahtu A, Laurén I, Veerman R, ..., Rockberg J, Mangsbo S
Nat Commun 15 (1) 9542 [2024-11-05; online 2024-11-05]
PubMed DOI Crossref
Perturbations in eIF3 subunit stoichiometry alter expression of ribosomal proteins and key components of the MAPK signaling pathways.
Herrmannová A, Jelínek J, Pospíšilová K, ..., Topisirovic I, Valášek LS
Elife 13 (-) - [2024-11-04; online 2024-11-04]
DOI Crossref
Perturbations in eIF3 subunit stoichiometry alter expression of ribosomal proteins and key components of the MAPK signaling pathways
Herrmannová A, Jelínek J, Pospíšilová K, ..., Topisirovic I, Valášek LS
Elife 13 (-) - [2024-11-04; online 2024-11-04]
PubMed DOI Crossref
Incontinentia pigmenti underlies thymic dysplasia, autoantibodies to type I IFNs, and viral diseases.
Rosain J, Le Voyer T, Liu X, ..., Anderson MS, Casanova JL
J. Exp. Med. 221 (11) - [2024-11-04; online 2024-10-01]
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A PERTURBATION CELL ATLAS OF HUMAN INDUCED PLURIPOTENT STEM CELLS.
Nourreddine S, Doctor Y, Dailamy A, ..., Krogan N, Mali P
bioRxiv - (-) - [2024-11-04; online 2024-11-04]
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Revised diffusion law permits quantitative nanoscale characterization of membrane organization
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Molecular Profiling Defines Three Subtypes of Synovial Sarcoma.
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MassiveFold: unveiling AlphaFold's hidden potential with optimized and parallelized massive sampling.
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Massive parallel sequencing-based non-invasive prenatal test (NIPT) identifies aberrations on chromosome 13.
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Loss of heterozygosity of CYP2D6 enhances the sensitivity of hepatocellular carcinomas to talazoparib.
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Daniel Globisch SciLifeLab Fellow
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Integration across biophysical scales identifies molecular and cellular correlates of person-to-person variability in human brain connectivity.
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GCKIII kinases control hepatocellular lipid homeostasis via shared mode of action.
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Epigenetic regulation by polycomb repressive complex 1 promotes cerebral cavernous malformations.
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Dynamic process simulation for life cycle inventory data acquisition – Environmental assessment of biological and chemical phosphorus removal
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Detach-ROCKET: sequential feature selection for time series classification with random convolutional kernels
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Depth-specific distribution of bacterial MAGs in permafrost active layer in Ny Ålesund, Svalbard (79°N).
Sipes K, Buongiorno J, Steen AD, ..., Vishnivetskaya TA, Lloyd KG
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Sarahi Garcia SciLifeLab Fellow
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Nat. Methods 21 (11) 2008-2012 [2024-11-00; online 2024-10-21]
DDLS Fellow Kaisa Thorell
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Boric Acid and Borax Protect Human Lymphocytes from Oxidative Stress and Genotoxicity Induced by 3-Monochloropropane-1,2-diol.
Turkez H, Tozlu OO, Arslan ME, ..., Tatar A, Mardinoglu A
Biol Trace Elem Res 202 (11) 5006-5016 [2024-11-00; online 2024-01-13]
Adil Mardinoglu SciLifeLab Fellow
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Automated multiplexed affinity-based enrichment of peptides for LC-MS/MS plasma proteomics.
Junior SM, Levander F
Proteomics 24 (21-22) e2400049 [2024-11-00; online 2024-08-27]
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Author Correction: Androgen receptor pathway inhibitors and taxanes in metastatic prostate cancer: an outcome-adaptive randomized platform trial.
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Antibody-displaying extracellular vesicles for targeted cancer therapy.
Wiklander OPB, Mamand DR, Mohammad DK, ..., Görgens A, El Andaloussi S
Nat Biomed Eng 8 (11) 1453-1468 [2024-11-00; online 2024-05-20]
Erdinc Sezgin SciLifeLab Fellow
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Androgen receptor pathway inhibitors and taxanes in metastatic prostate cancer: an outcome-adaptive randomized platform trial.
De Laere B, Crippa A, Discacciati A, ..., Grönberg H, Lindberg J
Nat. Med. 30 (11) 3291-3302 [2024-11-00; online 2024-08-20]
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An ancient ecospecies of Helicobacter pylori.
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Nature 635 (8037) 178-185 [2024-11-00; online 2024-10-16]
DDLS Fellow Kaisa Thorell
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Advances and controversies in meningeal biology.
Betsholtz C, Engelhardt B, Koh GY, ..., Proulx ST, Siegenthaler J
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Aberrant overexpression of myosin 1b in glioblastoma promotes angiogenesis via VEGF-myc-myosin 1b-Piezo1 axis.
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Adil Mardinoglu SciLifeLab Fellow
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Multi-omics characterization of lymphedema-induced adipose tissue resulting from breast cancer-related surgery.
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Adil Mardinoglu SciLifeLab Fellow
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Genomic codes governing enhancer RNA fate
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Magda Bienko SciLifeLab Fellow
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Time-resolved scattering methods for biological samples at the CoSAXS beamline, MAX IV Laboratory.
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Protumoral lipid droplet-loaded macrophages are enriched in human glioblastoma and can be therapeutically targeted.
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PKLR-modulating compounds show promising effects for the treatment of hepatocellular carcinoma
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Adil Mardinoglu SciLifeLab Fellow
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Mechanisms conferring bacterial cell wall variability and adaptivity.
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Biochem. Soc. Trans. 52 (5) 1981-1993 [2024-10-30; online 2024-09-26]
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High-parametric protein maps reveal the spatial organization in early-developing human lung.
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Sexual Dimorphism in the Immunometabolic Role of Gpr183 in Mice.
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Integrative spatial and genomic analysis of tumor heterogeneity with Tumoroscope.
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Nat Commun 15 (1) 9343 [2024-10-29; online 2024-10-29]
Camilla Engblom SciLifeLab Fellow
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Adil Mardinoglu SciLifeLab Fellow
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The ABCF ATPase New1 resolves translation termination defects associated with specific tRNAArg and tRNALys isoacceptors in the P site.
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Nucleic Acids Res. 52 (19) 12005-12020 [2024-10-28; online 2024-09-01]
SciLifeLab Fellow Vicente Pelechano
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Elucidating microRNA-34a organisation within human Argonaute-2 by dynamic nuclear polarisation-enhanced magic angle spinning NMR.
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Nucleic Acids Res. 52 (19) 11995-12004 [2024-10-28; online 2024-09-04]
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Data of the Insect Biome Atlas: a metabarcoding survey of the terrestrial arthropods of Sweden and Madagascar
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Smartphone-driven centrifugal microfluidics for diagnostics in resource limited settings.
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Biomed Microdevices 26 (4) 43 [2024-10-26; online 2024-10-26]
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Optimized method for fluorine-18 radiolabeling of Affibody molecules using RESCA.
Lechi F, Eriksson J, Odell LR, ..., Zhang B, Eriksson O
EJNMMI Radiopharm Chem 9 (1) 73 [2024-10-26; online 2024-10-26]
Olof Eriksson SciLifeLab Fellow
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Sequence-dependent scale for translocon-mediated insertion of interfacial helices in membranes
Grau B, Kormos R, Bañó-Polo M, ..., DeGrado WF, Mingarro I
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Novel Approach for Lifetime-Proportional Luminescence Imaging Using Frame Straddling.
Ahmerkamp S, Pacherres CO, Mosshammer M, ..., Koren K, Kühl M
ACS Sens 9 (10) 5531-5540 [2024-10-25; online 2024-10-14]
Lars Behrendt SciLifeLab Fellow
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Mitochondrial ETF insufficiency drives neoplastic growth by selectively optimizing cancer bioenergetics
Papadopoli D, Palia R, Jovanovic P, ..., Pollak M, Topisirovic I
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High-throughput biodiversity surveying sheds new light on the brightest of insect taxa
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Discovery of a Series of Macrocycles as Potent Inhibitors of Leishmania Infantum.
Riu F, Ruppitsch LA, Duy Vo D, ..., Sjö P, Kihlberg J
J Med Chem 67 (20) 18170-18193 [2024-10-24; online 2024-10-08]
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The energy metabolism of Cupriavidus necator in different trophic conditions.
Jahn M, Crang N, Gynnå AH, ..., Charpentier E, Hudson EP
Applied and environmental microbiology 90 (10) e0074824 [2024-10-23; online 2024-09-25]
Paul Hudson SciLifeLab Fellow
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Homologous Peptide Foldamer Promotes FUS Aggregation and Triggers Cancer Cell Death.
Wang MD, Yi L, Li Y, ..., Liu C, Wang H
Journal of the American Chemical Society 146 (42) 28669-28676 [2024-10-23; online 2024-10-15]
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Epigenome-wide analysis across the development span of pediatric acute lymphoblastic leukemia: backtracking to birth.
Ghantous A, Nusslé SG, Nassar FJ, ..., Munthe-Kaas MC, Herceg Z
Mol Cancer 23 (1) 238 [2024-10-23; online 2024-10-23]
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A unique metabolic gene cluster regulates lactose and galactose metabolism in the yeast Candida intermedia.
Peri KVR, Yuan L, Faria Oliveira F, ..., Kerkhoven EJ, Geijer C
Applied and environmental microbiology 90 (10) e0113524 [2024-10-23; online 2024-09-06]
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Quantitative proteomics of patient fibroblasts reveal biomarkers and diagnostic signatures of mitochondrial disease.
Correia SP, Moedas MF, Taylor LS, ..., Wedell A, Wredenberg A
JCI Insight 9 (20) - [2024-10-22; online 2024-10-22]
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Proteome-wide CETSA reveals diverse apoptosis-inducing mechanisms converging on an initial apoptosis effector stage at the nuclear periphery.
Ramos AD, Liang YY, Surova O, ..., Lööf S, Nordlund P
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Fish are poor sentinels for surveillance of riverine AMR
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DDLS Fellow Johan Bengtsson-Palme
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Bacterial spore surface nanoenvironment requires a AAA+ ATPase to promote MurG function.
Delerue T, Updegrove TB, Chareyre S, ..., Aravind L, Ramamurthi KS
Proc. Natl. Acad. Sci. U.S.A. 121 (43) e2414737121 [2024-10-22; online 2024-10-15]
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The DoGA consortium expression atlas of promoters and genes in 100 canine tissues.
Hörtenhuber M, Hytönen MK, Mukarram AK, ..., Kere J, Lohi H
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Crystallographic and NMR studies of Streptococcus pneumonia LCP protein Psr Sp indicate the importance of dynamics in four long loops for ligand specificity
Sandalova T, Sala BM, Moche M, ..., Agback P, Achour A
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Synthesis, Characterization, Theoretical Studies and in Vitro Embriyotoxic, Genotoxic and Anticancer Effects of Novel Phenyl(1,4,6-Triphenyl-2-Thioxo-1,2,3,4-Tetrahydropyrimidin-5-yl)Methanone
Akbas E, Othman KA, Çelikezen FÇ, ..., Yapca OE, Mardinoglu A
Polycyclic Aromatic Compounds 44 (9) 6284-6301 [2024-10-20; online 2023-11-03]
Adil Mardinoglu SciLifeLab Fellow
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Distinct molecular profiles and shared drug vulnerabilities in pancreatic metastases of renal cell carcinoma.
Roos-Mattila M, Kallio P, Luck TJ, ..., Pietiäinen VM, Seppänen HE
Commun Biol 7 (1) 1355 [2024-10-20; online 2024-10-20]
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Symmetry-adapted Markov state models of closing, opening, and desensitizing in α 7 nicotinic acetylcholine receptors.
Zhuang Y, Howard RJ, Lindahl E
Nat Commun 15 (1) 9022 [2024-10-18; online 2024-10-18]
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Perturbations in eIF3 subunit stoichiometry alter expression of ribosomal proteins and key components of the MAPK signaling pathways
Herrmannová A, Jelínek J, Pospíšilová K, ..., Topisirovic I, Valášek LS
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Autoantibodies to protein S may explain rare cases of coagulopathy following COVID-19 vaccination.
Yalcinkaya A, Cavalli M, Aranda-Guillén M, ..., Hallberg P, Landegren N
Sci Rep 14 (1) 24512 [2024-10-18; online 2024-10-18]
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Author response: Perturbations in eIF3 subunit stoichiometry alter expression of ribosomal proteins and key components of the MAPK signaling pathways
Herrmannová A, Jelínek J, Pospíšilová K, ..., Topisirovic I, Valášek LS
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Prevalent and persistent new-onset autoantibodies in mild to severe COVID-19.
Jernbom AF, Skoglund L, Pin E, ..., Månberg A, Nilsson P
Nat Commun 15 (1) 8941 [2024-10-17; online 2024-10-17]
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OS09.5.A UNEXPECTED FUNCTIONAL ROLE OF GLYCOCALYX ENCAPSULATION DURING GBM METABOLIC ADAPTATION OPENS AVENUES FOR NEW TREATMENT CONCEPTS
Bång-Rudenstam A, Cerezo-Magaña M, Gonçalves de Oliveira K, ..., Bengzon J, Belting M
Neuro-oncology 26 (Supplement_5) v26-v26 [2024-10-17; online 2024-10-17]
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Microbially Produced Bile Acids are Associated with High Levels of IgG Autoantibodies and Worse Mental Well-being in Fibromyalgia Subjects
Jakobsson JE, Carlsson H, Erngren I, ..., Svensson CI, Kultima K
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snPATHO-seq, a versatile FFPE single-nucleus RNA sequencing method to unlock pathology archives.
Wang T, Roach MJ, Harvey K, ..., Swarbrick A, Martelotto LG
Commun Biol 7 (1) 1340 [2024-10-16; online 2024-10-16]
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Temperature, sediment resuspension, and salinity drive the prevalence of Vibrio vulnificus in the coastal Baltic Sea.
Fernández-Juárez V, Riedinger DJ, Gusmao JB, ..., Labrenz M, Riemann L
MBio 15 (10) e0156924 [2024-10-16; online 2024-09-19]
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ESPressoscope: A small and powerful approach for in situ microscopy.
Li E, Saggiomo V, Ouyang W, Prakash M, Diederich B
PLoS ONE 19 (10) e0306654 [2024-10-16; online 2024-10-16]
DDLS Fellow Wei Ouyang
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Contributions of DNA Sequencing Technologies to the Integrative Monitoring of Karstic Caves
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Applied Sciences 14 (20) 9438 [2024-10-16; online 2024-10-16]
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VISION - an open-source software for automated multi-dimensional image analysis of cellular biophysics.
Weber F, Iskrak S, Ragaller F, ..., Sezgin E, Andronico LA
J. Cell. Sci. 137 (20) - [2024-10-15; online 2024-10-23]
Erdinc Sezgin SciLifeLab Fellow
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The crucial role of bioimage analysts in scientific research and publication.
Cimini BA, Bankhead P, D'Antuono R, ..., Wiggins L, Eliceiri KW
J. Cell. Sci. 137 (20) - [2024-10-15; online 2024-10-30]
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Machine learning in microscopy - insights, opportunities and challenges.
Cunha I, Latron E, Bauer S, Sage D, Griffié J
J. Cell. Sci. 137 (20) - [2024-10-15; online 2024-10-28]
DDLS Fellow Juliette Griffie
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IN VIVO APPLICATION OF LOCAL DRUG DELIVERY SYSTEMS AGAINST MEDULLOBLASTOMA GROUP 3 AND ATYPICAL/TERATOID/RHABOID TUMOURS
Moloney DC, McCrorie DP, ElSherbeny MA, ..., Smith DS, Rahman DR
Neuro-oncology 26 (Supplement_7) vii3-vii4 [2024-10-15; online 2024-10-15]
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Autoinflammation in patients with leukocytic CBL loss of heterozygosity is caused by constitutive ERK-mediated monocyte activation.
Bohlen J, Bagarić I, Vatovec T, ..., Casanova JL, Bustamante J
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Author Correction: The European Reference Genome Atlas: piloting a decentralised approach to equitable biodiversity genomics.
Mc Cartney AM, Formenti G, Mouton A, ..., Waterhouse RM, Mazzoni CJ
NPJ Biodivers 3 (1) 31 [2024-10-15; online 2024-10-15]
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Secondary Binding Site of CYP17A1 in Enhanced Sampling Simulations.
Wróbel TM, Bartuzi D, Kaczor AA
J Chem Inf Model 64 (19) 7679-7686 [2024-10-14; online 2024-09-26]
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Resilience of genetic diversity in forest trees over the Quaternary.
Milesi P, Kastally C, Dauphin B, ..., Pyhäjärvi T, GenTree Consortium
Nat Commun 15 (1) 8538 [2024-10-14; online 2024-10-14]
Pascal Milesi SciLifeLab Fellow
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Peer Review Report For: A research data management (RDM) community for ELIXIR [version 2; peer review: 2 approved]
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Metagenomic assemblies tend to break around antibiotic resistance genes.
Abramova A, Karkman A, Bengtsson-Palme J
BMC Genomics 25 (1) 959 [2024-10-14; online 2024-10-14]
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PubMed DOI Crossref
LRPPRC and SLIRP synergize to maintain sufficient and orderly mammalian mitochondrial translation.
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Nucleic Acids Res. 52 (18) 11266-11282 [2024-10-14; online 2024-08-01]
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Combining Data-Driven and Structure-Based Approaches in Designing Dual PARP1-BRD4 Inhibitors for Breast Cancer Treatment.
Feng B, Yu H, Dong X, ..., Antolin AA, Hu H
J Chem Inf Model 64 (19) 7725-7742 [2024-10-14; online 2024-09-18]
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Coagulation factor X promotes resistance to androgen-deprivation therapy in prostate cancer.
Calì B, Troiani M, Bressan S, ..., de Bono J, Alimonti A
Cancer Cell 42 (10) 1676-1692.e11 [2024-10-14; online 2024-09-19]
Arian Lundberg DDLS Fellow
PubMed DOI Crossref
Characterization of Nuclear Mitochondrial Insertions in Canine Genome Assemblies.
Schall PZ, Meadows JRS, Ramos-Almodovar F, Kidd JM
Genes (Basel) 15 (10) - [2024-10-14; online 2024-10-14]
PubMed DOI Crossref
Smart variant filtering - A blueprint solution for massively parallel sequencing-based variant analysis.
Brahimllari O, Eloranta S, Georgii-Hemming P, ..., Wästerlid T, Boman M
Health Informatics J 30 (4) 14604582241290725 [2024-10-12; online 2024-10-12]
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Fibromyalgia patients have altered lipid concentrations associated with disease symptom severity and anti-satellite glial cell IgG antibodies
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PubMed DOI Crossref
Methotrexate promotes the release of granulocyte-macrophage colony-stimulating factor from rheumatoid arthritis fibroblast-like synoviocytes via autocrine interleukin-1 signaling.
Bergström B, Selldén T, Bollmann M, Svensson MND, Ekwall AH
Arthritis Res Ther 26 (1) 178 [2024-10-11; online 2024-10-11]
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Maintenance of cell wall remodeling and vesicle production are connected in Mycobacterium tuberculosis
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Isotope Encoded chemical Imaging Identifies Amyloid Plaque Age Dependent Structural Maturation, Synaptic Loss, and Increased Toxicity.
Wood JI, Dulewicz M, Ge J, ..., Edwards FA, Hanrieder J
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Affibody-Drug Conjugates Targeting the Human Epidermal Growth Factor Receptor-3 Demonstrate Therapeutic Efficacy in Mice Bearing Low Expressing Xenografts.
Zhang J, Rinne SS, Yin W, ..., Gräslund T, Vorobyeva A
ACS pharmacology & translational science 7 (10) 3228-3240 [2024-10-11; online 2024-09-12]
DOI Crossref
Properties and limitations of eDNA substrates for terrestrial animal monitoring
Zhao B, Andermann T
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DDLS Fellow Tobias Andermann
PubMed DOI Crossref
New connections of medication use and polypharmacy with the gut microbiota composition and functional potential in a large population.
Larsson A, Ericson U, Jönsson D, ..., Maziarz M, Orho-Melander M
Sci Rep 14 (1) 23723 [2024-10-10; online 2024-10-10]
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Deep plasma proteomics identifies and validates an eight-protein biomarker panel that separate benign from malignant tumors in ovarian cancer
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Unmasking AlphaFold to integrate experiments and predictions in multimeric complexes.
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Nat Commun 15 (1) 8724 [2024-10-09; online 2024-10-09]
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SlipO2Chip - single-cell respiration under tuneable environments.
Cui Y, Moreira MA, Whalen KE, ..., Tenje M, Behrendt L
Lab Chip 24 (20) 4786-4797 [2024-10-09; online 2024-10-09]
Lars Behrendt SciLifeLab Fellow
PubMed DOI Crossref
Quest for Orthologs in the Era of Biodiversity Genomics.
Langschied F, Bordin N, Cosentino S, ..., Dessimoz C, Ebersberger I
Genome Biol Evol 16 (10) - [2024-10-09; online 2024-10-15]
DDLS Fellow Sina Majidian
PubMed DOI Crossref
In Situ Functionalization of Polar Polythiophene-Based Organic Electrochemical Transistor to Interface In Vitro Models.
Buchmann S, Stoop P, Roekevisch K, ..., Zeglio E, Herland A
ACS Appl Mater Interfaces 16 (40) 54292-54303 [2024-10-09; online 2024-09-27]
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Peripartum depression symptom trajectories, telomere length and genotype, and adverse childhood experiences.
Vrettou M, Lager S, Toffoletto S, ..., Skalkidou A, Comasco E
BMC Psychiatry 24 (1) 661 [2024-10-08; online 2024-10-08]
Erika Comasco SciLifeLab Fellow
PubMed DOI Crossref
Identification of novel and potent inhibitors of SARS-CoV-2 main protease from DNA-encoded chemical libraries.
Akaberi D, Pourghasemi Lati M, Krambrich J, ..., Verho O, Lennerstrand J
Antimicrob. Agents Chemother. 68 (10) e0090924 [2024-10-08; online 2024-08-28]
PubMed DOI Crossref
Estradiol-mediated enhancement of the human ectocervical epithelial barrier correlates with desmoglein-1 expression in the follicular menstrual phase.
Bradley F, Stern A, Franzén Boger M, ..., Fowke KR, Broliden K
Front Endocrinol (Lausanne) 15 (-) 1454006 [2024-10-08; online 2024-10-08]
PubMed DOI Crossref
Chemical Exposomics in Human Plasma by Lipid Removal and Large-Volume Injection Gas Chromatography-High-Resolution Mass Spectrometry.
Xie H, Sdougkou K, Bonnefille B, ..., Rantakokko P, Martin JW
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Call for Papers for a Special Issue on “Ocean Health”
Dachs J, Boehm A, Sunderland E, ..., Schlenk D, Brooks B
Environ Sci Technol Lett 11 (10) 1016-1016 [2024-10-08; online 2024-10-08]
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Call for Papers for a Special Issue on “Ocean Health”
Dachs J, Boehm A, Sunderland E, ..., Schlenk D, Brooks B
Environ. Sci. Technol. 58 (40) 17523-17523 [2024-10-08; online 2024-10-08]
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The molecular infrastructure of glutamatergic synapses in the mammalian forebrain
Peukes J, Lovatt C, Leistner C, ..., Grant SG, Frank RA
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LOW COST, PORTABLE DNA NANOBALL AMPLIFICATION KIT TO INTEGRATE WITH AND PERFORM LAMP REACTION IN A POINT-OF-CARE DIGITAL ASSAY FOR RAPID ELECTRONIC QUANTIFICATION OF CLINICAL PATHOGENS USING DNA NANOBALLS
Karimi K, Barrett D, Chille E, ..., Pelechano V, Javanmard M
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SciLifeLab Fellow
PubMed DOI Crossref
Characteristics of gene expression in epicardial adipose tissue and subcutaneous adipose tissue in patients at risk for heart failure undergoing coronary artery bypass grafting.
Frisk C, Ekström M, Eriksson MJ, ..., Linde C, Persson B
BMC Genomics 25 (1) 938 [2024-10-07; online 2024-10-07]
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A topographic lung cell atlas reveals regional variation in cell-type specific gene programs and identifies healthy and diseased cellular neighborhoods
Samakovlis C, Firsova A, Salas SM, ..., Nilsson M, Nawijn M
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Genetic Adaptation to Amoxicillin inEscherichia coli: The Limited Role ofdinBandkatE
Teichmann L, Wenne M, Luitwieler S, ..., Bengtsson-Palme J, Kuile Bt
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DDLS Fellow Johan Bengtsson-Palme
PubMed DOI Crossref
Pesticide-induced transgenerational alterations of genome-wide DNA methylation patterns in the pancreas of Xenopus tropicalis correlate with metabolic phenotypes.
Roza M, Eriksson ANM, Svanholm S, Berg C, Karlsson O
J Hazard Mater 478 (-) 135455 [2024-10-05; online 2024-08-09]
Oskar Karlsson SciLifeLab Fellow
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Beyond Tumors: Reduced survival linked to pathogenic PIK3CA and TP53 post-zygotic variants in the uninvolved breast tissue of recurrent cancer patients
Andreou M, Chojnowska K, Filipowicz N, ..., Dumanski JP, Piotrowski A
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A genotype-first approach identifies variants for orofacial clefts and other phenotypes in dogs
Buckley RM, Bilgen N, Harris AC, ..., Boyko AR, Ostrander EA
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PubMed DOI Crossref
Quantification of Anisotropy in Exchange and Dispersion Interactions: A Simple Model for Physics-Based Force Fields.
Kříž K, van der Spoel D
J Phys Chem Lett 15 (39) 9974-9978 [2024-10-03; online 2024-09-24]
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Peer Review Report For: A research data management (RDM) community for ELIXIR [version 2; peer review: 2 approved]
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PubMed DOI Crossref
Genetics of immune response to Epstein-Barr virus: prospects for multiple sclerosis pathogenesis.
Huang J, Tengvall K, Lima IB, ..., Olsson T, Kockum I
Brain 147 (10) 3573-3582 [2024-10-03; online 2024-04-17]
DOI Crossref
A thermoplastic chip for correlative assays combining screening and high-resolution imaging of immune cell responses
van Ooijen H, Verron Q, Zhang H, ..., Sandström N, Önfelt B
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Patrick Sandoz SciLifeLab Fellow
PubMed DOI Crossref
Multi-omics analysis reveals the key factors involved in the severity of the Alzheimer's disease.
Meng L, Jin H, Yulug B, ..., Uhlén M, Mardinoglu A
Alzheimers Res Ther 16 (1) 213 [2024-10-02; online 2024-10-02]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
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Dimensionality Reduction of Genetic Data using Contrastive Learning
Thor F, Nettelblad C
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PubMed DOI Crossref
Unveiling the Molecular Mechanisms of Glioblastoma through an Integrated Network-Based Approach.
Kaynar A, Kim W, Ceyhan AB, ..., Shoaie S, Mardinoglu A
Biomedicines 12 (10) - [2024-10-01; online 2024-10-01]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
DOI Crossref
Spatial multiomic insights into acute cocaine exposure
Nezhyva M, Shahen-Zoabi S, Kabirova M, ..., Margulis K, Jansson ET
PNAS Nexus 3 (10) - [2024-10-01; online 2024-10-10]
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Spatial Transcriptome Mapping of the Desmoplastic Growth Pattern of Colorectal Liver Metastases by In Situ Sequencing Reveals a Biologically Relevant Zonation of the Desmoplastic Rim.
Andersson A, Escriva Conde M, Surova O, ..., Nilsson M, Nyström H
Clin. Cancer Res. 30 (19) 4517-4529 [2024-10-01; online 2024-07-26]
PubMed DOI Crossref
RNA sequencing reveals molecular mechanisms of endometriosis lesion development in mice.
Panir K, Schjenken JE, Breen J, ..., Robertson SA, Hull ML
Dis Model Mech 17 (10) - [2024-10-01; online 2024-10-23]
DOI Crossref
Lamins regulate nuclear mechanics and shape to control glioblastoma cell proliferation, migration and invasion
Wang X, Pereira D, Perfettini I, ..., Etienne-Manneville S, Manneville JB
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PubMed DOI Crossref
IL-7-dependent and -independent lineages of IL-7R-dependent human T cells.
Arango-Franco CA, Ogishi M, Unger S, ..., Casanova JL, Puel A
J. Clin. Invest. 134 (19) - [2024-10-01; online 2024-10-01]
PubMed DOI Crossref
Gene expression-phenotype association study reveals the dual role of TNF-α/TNFR1 signaling axis in confined breast cancer cell migration.
Cruceriu D, Balacescu L, Baldasici O, ..., Irimia D, Tudoran O
Life Sci 354 (-) 122982 [2024-10-01; online 2024-08-14]
PubMed DOI Crossref
Evaluation of Nontargeted Mass Spectral Data Acquisition Strategies for Water Analysis and Toxicity-Based Feature Prioritization by MS2Tox.
Peets P, Rian MB, Martin JW, Kruve A
Environ. Sci. Technol. 58 (39) 17406-17418 [2024-10-01; online 2024-09-19]
PubMed DOI Crossref
Engineered modular neuronal networks-on-chip represent structure-function relationship.
Habibey R, Striebel J, Meinert M, ..., Nasiri R, Latifi S
Biosens Bioelectron 261 (-) 116518 [2024-10-01; online 2024-06-22]
PubMed DOI Crossref
DockQ v2: improved automatic quality measure for protein multimers, nucleic acids, and small molecules.
Mirabello C, Wallner B
Bioinformatics 40 (10) - [2024-10-01; online 2024-09-30]
PubMed DOI Crossref
Determining Marine Biodegradation Kinetics of Chemicals Discharged from Offshore Oil Platforms─Whole Mixture Testing at High Dilutions Increases Environmental Relevance.
Møller MT, Birch H, Sjøholm KK, ..., Papazian S, Mayer P
Environ. Sci. Technol. 58 (39) 17454-17463 [2024-10-01; online 2024-09-18]
PubMed DOI Crossref
Chloroplastic ascorbate modifies plant metabolism and may act as a metabolite signal regardless of oxidative stress.
Tóth D, Tengölics R, Aarabi F, ..., Papp B, Tóth SZ
Plant Physiol. 196 (2) 1691-1711 [2024-10-01; online 2024-08-06]
Paul Hudson SciLifeLab Fellow
PubMed DOI Crossref
Association between neighborhood socioeconomic status and healthcare utilization among individuals with a first diagnosis of major depressive disorder in primary care in the Stockholm region.
Gannedahl A, Björkholm C, Leval A, ..., Hellner C, Lundberg J
J Affect Disord 362 (-) 96-103 [2024-10-01; online 2024-06-22]
PubMed DOI Crossref
Yeast9: a consensus genome-scale metabolic model for S. cerevisiae curated by the community.
Zhang C, Sánchez BJ, Li F, ..., Lu H, Kerkhoven EJ
Mol Syst Biol 20 (10) 1134-1150 [2024-10-00; online 2024-08-12]
PubMed DOI Crossref
The genomes of all lungfish inform on genome expansion and tetrapod evolution.
Schartl M, Woltering JM, Irisarri I, ..., Schneider I, Meyer A
Nature 634 (8032) 96-103 [2024-10-00; online 2024-08-14]
PubMed DOI Crossref
The genetic architecture of repeated local adaptation to climate in distantly related plants.
Whiting JR, Booker TR, Rougeux C, ..., Zhou L, Yeaman S
Nat Ecol Evol 8 (10) 1933-1947 [2024-10-00; online 2024-08-26]
Pascal Milesi SciLifeLab Fellow
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The ACROBAT 2022 challenge: Automatic registration of breast cancer tissue.
Weitz P, Valkonen M, Solorzano L, ..., Ruusuvuori P, Rantalainen M
Med Image Anal 97 (-) 103257 [2024-10-00; online 2024-07-01]
DDLS Fellow Kimmo Kartasalo
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The 'queen of the Andes' (Puya raimondii) is genetically fragile and fragmented: a consequence of long generation time and semelparity?
Liu L, James J, Zhang YQ, ..., Lascoux M, Ge XJ
New Phytol. 244 (1) 277-291 [2024-10-00; online 2024-08-12]
DDLS Fellow Jennifer James
PubMed DOI Crossref
Structure prediction analysis of human core TIM23 complex reveals conservation of the protein translocation mechanism.
Maruszczak KK, Draczkowski P, Wnorowski A, Chacinska A
FEBS Open Bio 14 (10) 1656-1667 [2024-10-00; online 2024-06-04]
DOI Crossref
Sex bias in FGFR3 somatic mutations in bladder cancer
Meng X, Wang Q
Oncol Transl Med 10 (5) 252-256 [2024-10-00; online 2024-08-12]
DDLS Fellow Qiaoli Wang
PubMed DOI Crossref
Proteomic changes in Alzheimer's disease associated with progressive Aβ plaque and tau tangle pathologies.
Pichet Binette A, Gaiteri C, Wennström M, ..., Vogel JW, Hansson O
Nat. Neurosci. 27 (10) 1880-1891 [2024-10-00; online 2024-08-26]
DDLS Fellow Jacob W Vogel
PubMed DOI Crossref
Production of stable and pure ZC3H11A - An extensively disordered RNA binding protein.
Fekry M, Stenberg G, Dobritzsch D, Danielson UH
Protein Expr. Purif. 222 (-) 106542 [2024-10-00; online 2024-07-04]
PubMed DOI Crossref
Personalized mixture toxicity testing: A proof-of-principle in vitro study evaluating the steroidogenic effects of reconstructed contaminant mixtures measured in blood of individual adults.
Strand D, Lundgren B, Bergdahl IA, Martin JW, Karlsson O
Environ Int 192 (-) 108991 [2024-10-00; online 2024-08-30]
Oskar Karlsson SciLifeLab Fellow
PubMed DOI Crossref
PDGF-induced internalisation promotes proteolytic cleavage of PDGFRβ in mesenchymal cells.
Rubin Sander M, Tsiatsiou AK, Wang K, ..., Heldin CH, Lennartsson J
Growth Factors 42 (4) 147-160 [2024-10-00; online 2024-10-10]
PubMed DOI Crossref
Multiplex plasma protein assays as a diagnostic tool for lung cancer.
Ahamed MT, Forshed J, Levitsky A, ..., Eriksson LE, Andersson B
Cancer Sci. 115 (10) 3439-3454 [2024-10-00; online 2024-07-30]
PubMed DOI Crossref
Multifaceted Proteome Analysis at Solubility, Redox, and Expression Dimensions for Target Identification.
Saei AA, Lundin A, Lyu H, ..., Gygi SP, Zubarev RA
Adv Sci (Weinh) 11 (38) e2401502 [2024-10-00; online 2024-08-09]
PubMed DOI Crossref
Lipidome changes due to improved dietary fat quality inform cardiometabolic risk reduction and precision nutrition.
Eichelmann F, Prada M, Sellem L, ..., Schulze MB, Wittenbecher C
Nat. Med. 30 (10) 2867-2877 [2024-10-00; online 2024-07-11]
Clemens Wittenbecher DDLS Fellow
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Leveraging zebrafish to investigate pancreatic development, regeneration, and diabetes.
Mi J, Ren L, Andersson O
Trends in molecular medicine 30 (10) 932-949 [2024-10-00; online 2024-06-01]
PubMed DOI Crossref
LD-transpeptidation is crucial for fitness and polar growth in Agrobacterium tumefaciens.
Aliashkevich A, Guest T, Alvarez L, ..., Brown PJB, Cava F
PLoS Genet 20 (10) e1011449 [2024-10-00; online 2024-10-21]
PubMed DOI Crossref
Kinetic and structural characterization of NUDT15 and NUDT18 as catalysts of isoprene pyrophosphate hydrolysis.
Scaletti ER, Unterlass JE, Almlöf I, ..., Stenmark P, Jemth AS
FEBS J. 291 (19) 4301-4322 [2024-10-00; online 2024-06-29]
PubMed DOI Crossref
Iron deficiency in new onset heart failure: association with clinical factors and quality of life.
Cabrera CC, Ekström M, Tornvall P, ..., Persson B, Lyngå P
ESC Heart Fail 11 (5) 2661-2671 [2024-10-00; online 2024-05-27]
DOI Crossref
Heparin and heparan sulfate—The essence of sequence
Kjellén L, Lindahl U
Proteoglycan Research 2 (4) - [2024-10-00; online 2024-11-05]
PubMed DOI Crossref
Genetic Stock Identification Reveals Mismatches Between Management Areas and Population Genetic Structure in a Migratory Pelagic Fish.
Seljestad GW, Quintela M, Bekkevold D, ..., Glover KA, Berg F
Evol Appl 17 (10) e70030 [2024-10-00; online 2024-10-24]
PubMed DOI Crossref
Generation of a ZEB2 deficient human iPSC line (KICRi002A-4).
Schuster J, Fatima A, Papadopoulos N, ..., Sobol M, Dahl N
Stem Cell Res 80 (-) 103521 [2024-10-00; online 2024-07-31]
PubMed DOI Crossref
Emerging methods and applications in 3D genomics.
Pedrotti S, Castiglioni I, Perez-Estrada C, ..., Crosetto N, Bienko M
Curr Opin Cell Biol 90 (-) 102409 [2024-10-00; online 2024-08-22]
Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
Design and evaluation of novel inhibitors for the treatment of clear cell renal cell carcinoma.
Bouzian Y, El Hafi M, Parvizi N, ..., Turkez H, Mardinoglu A
Bioorg Chem 151 (-) 107597 [2024-10-00; online 2024-07-06]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Blood lipid profiling indicates that dietary fat quality is associated with cardiometabolic risk.
Nat. Med. 30 (10) 2735-2736 [2024-10-00; online 2024-08-31]
Clemens Wittenbecher DDLS Fellow
PubMed DOI Crossref
Beyond basic characterization and omics: Immunomodulatory roles of platelet-derived extracellular vesicles unveiled by functional testing.
Palviainen M, Puutio J, Østergaard RH, ..., Hayashi Y, Siljander PR
J Extracell Vesicles 13 (10) e12513 [2024-10-00; online 2024-09-27]
PubMed DOI Crossref
Bayesian polynomial neural networks and polynomial neural ordinary differential equations.
Fronk C, Yun J, Singh P, Petzold L
PLoS Comput Biol 20 (10) e1012414 [2024-10-00; online 2024-10-10]
Prashant Singh SciLifeLab Fellow
PubMed DOI Crossref
Author Correction: Immune system adaptation during gender-affirming testosterone treatment.
Lakshmikanth T, Consiglio C, Sardh F, ..., Landegren N, Brodin P
Nature 634 (8033) E5 [2024-10-00; online 2024-09-25]
Camila Consiglio DDLS Fellow
PubMed DOI Crossref
Associations between epigenetic aging and diabetes mellitus in a Swedish longitudinal study.
Wikström Shemer D, Mostafaei S, Tang B, ..., Fall T, Hägg S
Geroscience 46 (5) 5003-5014 [2024-10-00; online 2024-06-27]
PubMed DOI Crossref
Assessment of the exposure to cytotoxic Bacillus cereus group genotypes through high-temperature, short-time milk consumption.
Su J, Chandross-Cohen T, Qian C, ..., Wiedmann M, Kovac J
J Dairy Sci 107 (10) 7631-7647 [2024-10-00; online 2024-06-06]
DDLS Fellow Laura Carroll
DOI Crossref
Accurate determination of body composition of patients with breast cancer through MRI image analysis
De Giulio MM, Abeltino A, Riente A, ..., De Spirito M, Maulucci GM
Clinical Nutrition ESPEN 63 (-) 996 [2024-10-00; online 2024-10-00]
PubMed DOI Crossref
A virally encoded tRNA neutralizes the PARIS antiviral defence system.
Burman N, Belukhina S, Depardieu F, ..., Wiedenheft B, Isaev A
Nature 634 (8033) 424-431 [2024-10-00; online 2024-08-07]
PubMed DOI Crossref
A versatile tissue-rolling technique for spatial-omics analyses of the entire murine gastrointestinal tract.
Monasterio G, Morales RA, Bejarano DA, ..., Das S, Villablanca EJ
Nat Protoc 19 (10) 3085-3137 [2024-10-00; online 2024-06-21]
PubMed DOI Crossref
A cocktail of histidine, carnosine, cysteine and serine reduces adiposity and improves metabolic health and adipose tissue immunometabolic function in ovariectomized rats.
Baudin J, Hernandez-Baixauli J, Romero-Giménez J, ..., Arola L, Caimari A
Biomed. Pharmacother. 179 (-) 117326 [2024-10-00; online 2024-08-28]
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376 (PB364): Targeting TGF-β signaling components to ameliorate Palbociclib resistance in breast cancer
Ali M, Itoh Y, Heldin CH, Moustakas A
Eur. J. Cancer 211 (-) 114889 [2024-10-00; online 2024-10-00]
PubMed DOI Crossref
Calling for allied efforts to strengthen digital health literacy in Sweden: perspectives of policy makers.
Bywall KS, Norgren T, Avagnina B, ..., Andersson SW, IDEAHL consortium
BMC Public Health 24 (1) 2666 [2024-09-30; online 2024-09-30]
PubMed DOI Crossref
SETD8 inhibition targets cancer cells with increased rates of ribosome biogenesis.
Murga M, Lopez-Pernas G, Soliva R, ..., Orozco M, Fernández-Capetillo O
Cell Death Dis 15 (9) 694 [2024-09-28; online 2024-09-28]
DOI Crossref
MirGeneDB 3.0: Improved taxonomic sampling, uniform nomenclature of novel conserved microRNA families, and updated covariance models
Clarke AW, Høye E, Hembrom AA, ..., Peterson KJ, Fromm B
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Marc Friedländer SciLifeLab Fellow
PubMed DOI Crossref
Association of corticosteroid therapy with reduced acute kidney injury and lower NET markers in severe COVID-19: an observational study.
Bülow Anderberg S, Huckriede J, Hultström M, ..., Nicolaes GAF, Frithiof R
Intensive Care Med Exp 12 (1) 85 [2024-09-28; online 2024-09-28]
PubMed DOI Crossref
The regulatory landscape of interacting RNA and protein pools in cellular homeostasis and cancer.
Gallardo-Dodd CJ, Kutter C
Hum Genomics 18 (1) 109 [2024-09-27; online 2024-09-27]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Syngap1 Promotes Cognitive Function through Regulation of Cortical Sensorimotor Dynamics.
Vaissiere T, Michaelson SD, Creson T, ..., Fontolan L, Rumbaugh G
bioRxiv - (-) - [2024-09-27; online 2024-09-27]
Daniel Fürth SciLifeLab Fellow
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SpLitteR: diploid genome assembly using TELL-Seq linked-reads and assembly graphs.
Tolstoganov I, Chen Z, Pevzner P, Korobeynikov A
PeerJ 12 (-) e18050 [2024-09-27; online 2024-09-27]
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Peer Review Report For: Facilitating accessible, rapid, and appropriate processing of ancient metagenomic data with AMDirT [version 2; peer review: 1 approved, 3 approved with reservations]
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Multiomic biomarkers after cardiac arrest.
Stopa V, Lileikyte G, Bakochi A, ..., Nielsen N, Devaux Y
Intensive Care Med Exp 12 (1) 83 [2024-09-27; online 2024-09-27]
PubMed DOI Crossref
Merging multi-omics with proteome integral solubility alteration unveils antibiotic mode of action.
Maity R, Zhang X, Liberati FR, ..., Aínsa JA, Sancho J
Elife 13 (-) - [2024-09-27; online 2024-09-27]
DOI Crossref
Merging multi-omics with proteome integral solubility alteration unveils antibiotic mode of action
Maity R, Zhang X, Liberati FR, ..., Aínsa JA, Sancho J
Elife 13 (-) - [2024-09-27; online 2024-09-27]
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Introducing synthetic thermostable RNase inhibitors to single-cell RNA-seq.
Noble JC, Lentini A, Hagemann-Jensen M, Sandberg R, Reinius B
Nat Commun 15 (1) 8373 [2024-09-27; online 2024-09-27]
Antonio Lentini DDLS Fellow
PubMed DOI Crossref
Antimicrobial Dihydroflavonols and Isoflavans Isolated from the Root Bark of Dalbergia gloveri.
Kiganda I, Wieske LHE, Nchiozem-Ngnitedem VA, ..., Yenesew A, Erdelyi M
J Nat Prod 87 (9) 2263-2271 [2024-09-27; online 2024-09-10]
Ruisheng Xiong SciLifeLab Fellow
DOI Crossref
Targeting mutant p53: Evaluation of novel anti-p53 R175H monoclonal antibodies as diagnostic tools
Spiegelberg D, Hwang LA, Pua KH, ..., Nestor M, Lane DP
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DOI Crossref
Naturally acquired IgG responses to Plasmodium falciparum do not target the conserved termini of the malaria vaccine candidate merozoite surface protein 2
Zerebinski J, Margerie L, Han NS, ..., Färnert A, Plaza D
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DOI Crossref
FROG Analysis Ensures the Reproducibility of Genome Scale Metabolic Models
Raman K, Kratochvíl M, Olivier BG, ..., Dräger A, Malik-Sheriff RS
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Discovery of 2-Aryl-4-aminoquinazolin-Based LSD1 Inhibitors to Activate Immune Response in Gastric Cancer.
Wang B, Wang SW, Zhou Y, ..., Chen XB, Dai XJ
J Med Chem 67 (18) 16165-16184 [2024-09-26; online 2024-09-12]
Adil Mardinoglu SciLifeLab Fellow
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varCADD: large sets of standing genetic variation enable genome-wide pathogenicity prediction
Nazaretyan L, Rentzsch P, Kircher M
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PubMed DOI Crossref
Single-cell dissection of the human blood-brain barrier and glioma blood-tumor barrier.
Xie Y, Yang F, He L, ..., Wang L, Zhang L
Neuron 112 (18) 3089-3105.e7 [2024-09-25; online 2024-08-26]
PubMed DOI Crossref
Gastrin-releasing peptide receptor as theranostic target in estrogen-receptor positive breast cancer: A preclinical study of the theranostic pair [55Co]Co- and [177Lu]Lu-DOTA-RM26.
Baun C, Olsen BB, Alves CML, ..., Dam JH, Thisgaard H
Nucl. Med. Biol. 138-139 (-) 108961 [2024-09-25; online 2024-09-25]
PubMed DOI Crossref
Enhancing T-cell recruitment in renal cell carcinoma with cytokine-armed adenoviruses.
Feodoroff M, Hamdan F, Antignani G, ..., Grönholm M, Cerullo V
Oncoimmunology 13 (1) 2407532 [2024-09-25; online 2024-09-25]
PubMed DOI Crossref
A resource of identified and annotated lincRNAs expressed during somatic embryogenesis development in Norway spruce.
Canovi C, Stojkovič K, Benítez AA, ..., Egertsdotter U, Street NR
Physiol Plant 176 (5) e14537 [2024-09-25; online 2024-09-25]
DOI Crossref
The Organelle in the Ointment: improved detection of cryptic mitochondrial reads resolves many unknown sequences in cross-species microbiome analyses
Sonett D, Brown T, Bengtsson-Palme J, Padilla-Gamiño JL, Zaneveld JR
ISME Commun - (-) - [2024-09-24; online 2024-09-24]
DDLS Fellow Johan Bengtsson-Palme
DOI Crossref
Longitudinal analysis of genetic and environmental interplay in human metabolic profiles and the implication for metabolic health
Wang J, Zenere A, Wang X, ..., Uhlén M, Zhong W
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DDLS Fellow Fredrik Edfors
DOI Crossref
Mouse PAW: reverse-translating the FINGER multimodal lifestyle intervention enhances synaptic plasticity and cognition in adult wild type female mice
Alanko V, Eroli F, Végvári Á, ..., Maioli S, Matton A
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PubMed DOI Crossref
Making PBPK models more reproducible in practice.
Domínguez-Romero E, Mazurenko S, Scheringer M, ..., Županič A, Suarez-Diez M
Brief. Bioinformatics 25 (6) - [2024-09-23; online 2024-11-04]
PubMed DOI Crossref
Improved sub-genomic RNA prediction with the ARTIC protocol.
Baudeau T, Sahlin K
Nucleic Acids Res. 52 (17) e82 [2024-09-23; online 2024-08-16]
Kristoffer Sahlin SciLifeLab Fellow
PubMed DOI Crossref
A machine learning-based prediction of tau load and distribution in Alzheimer's disease using plasma, MRI and clinical variables.
Karlsson L, Vogel J, Arvidsson I, ..., Mattsson-Carlgren N, Hansson O
medRxiv - (-) - [2024-09-23; online 2024-09-23]
PubMed DOI Crossref
Microgravity Effect on Pancreatic Islets.
Zeger L, Barasa P, Han Y, ..., Christoffersson G, Kozlova EN
Cells 13 (18) - [2024-09-21; online 2024-09-21]
Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
Multi-omics analysis of aggregative multicellularity.
Edelbroek B, Westholm JO, Bergquist J, Söderbom F
iScience 27 (9) 110659 [2024-09-20; online 2024-08-03]
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Flow – SPPS towards greener and more efficient peptide manufacturing
Kracker O, Sachs EF
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PubMed DOI Crossref
Cancer associated variant enrichment CAVE, a gene agnostic approach to identify low burden variants in chronic lymphocytic leukemia.
Yaacov A, Lazarian G, Pandzic T, ..., Rosenberg S, Soussi T
Sci Rep 14 (1) 21962 [2024-09-20; online 2024-09-20]
DOI Crossref
FunCoup 6: advancing functional association networks across species with directed links and improved user experience
Buzzao D, Persson E, Guala D, Sonnhammer ELL
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PubMed DOI Crossref
Claustrum and dorsal endopiriform cortex complex cell-identity is determined by Nurr1 and regulates hallucinogenic-like states in mice.
Mantas I, Flais I, Masarapu Y, ..., Perlmann T, Svenningsson P
Nat Commun 15 (1) 8176 [2024-09-18; online 2024-09-18]
DOI Crossref
Characterization of nuclear mitochondrial insertions in canine genome assemblies
Schall PZ, Meadows JRS, Ramos-Almodovar F, Kidd JM
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PubMed DOI Crossref
Biodiversity of microorganisms in the Baltic Sea: the power of novel methods in the identification of marine microbes.
Mazur-Marzec H, Andersson AF, Błaszczyk A, ..., Witkowski A, Węgrzyn A
FEMS Microbiol Rev 48 (5) - [2024-09-18; online 2024-10-06]
PubMed DOI Crossref
The European Reference Genome Atlas: piloting a decentralised approach to equitable biodiversity genomics.
Mc Cartney AM, Formenti G, Mouton A, ..., Waterhouse RM, Mazzoni CJ
NPJ Biodivers 3 (1) 28 [2024-09-17; online 2024-09-17]
PubMed DOI Crossref
Proteo-metabolomics and patient tumor slice experiments point to amino acid centrality for rewired mitochondria in fibrolamellar carcinoma.
Long D, Chan M, Han M, ..., Gujral TS, Sethupathy P
Cell Rep Med 5 (9) 101699 [2024-09-17; online 2024-08-28]
PubMed DOI Crossref
Monitoring SARS-CoV-2 IgA, IgM and IgG antibodies in dried blood and saliva samples using antibody proximity extension assays (AbPEA).
Wang M, Kamali-Moghaddam M, Löf L, ..., Landegren U, Zhao H
Sci Rep 14 (1) 21655 [2024-09-17; online 2024-09-17]
PubMed DOI Crossref
Longitudinal Exposomics in a Multiomic Wellness Cohort Reveals Distinctive and Dynamic Environmental Chemical Mixtures in Blood.
Sdougkou K, Papazian S, Bonnefille B, ..., Martin LJ, Martin JW
Environ. Sci. Technol. 58 (37) 16302-16315 [2024-09-17; online 2024-09-05]
DDLS Fellow Fredrik Edfors
PubMed DOI Crossref
Integrating amyloid and tau imaging with proteomics and genomics in Alzheimer's disease.
Vilkaite G, Vogel J, Mattsson-Carlgren N
Cell Rep Med 5 (9) 101735 [2024-09-17; online 2024-09-19]
PubMed DOI Crossref
Contextualising samples: supporting reference genomes of European biodiversity through sample and associated metadata collection.
Böhne A, Fernández R, Leonard JA, ..., Vinnere Pettersson O, Struck TH
NPJ Biodivers 3 (1) 26 [2024-09-17; online 2024-09-17]
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Conserved Evolutionary Response to Whole Genome Duplication in Angiosperms Revealed Using High Resolution Gene Expression Profiling
Leal JL, Hodková E, Billhardt A, ..., Salojärvi J, Lascoux M
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Pascal Milesi SciLifeLab Fellow
PubMed DOI Crossref
BCL2 expression is enriched in advanced prostate cancer with features of lineage plasticity.
Westaby D, Jiménez-Vacas JM, Figueiredo I, ..., de Bono J, Sharp A
J. Clin. Invest. 134 (18) - [2024-09-17; online 2024-09-17]
Arian Lundberg DDLS Fellow
PubMed DOI Crossref
Aurora B and Aurora C pools at two chromosomal regions collaboratively maintain chromosome alignment and prevent aneuploidy at the second meiotic division in mammalian oocytes.
Kouznetsova A, Valentiniene S, Liu JG, ..., Brismar H, Höög C
Front Cell Dev Biol 12 (-) 1470981 [2024-09-17; online 2024-09-17]
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An Improved Chromosome-scale Genome Assembly and Population Genetics resource for Populus tremula.
Robinson KM, Schiffthaler B, Liu H, ..., Ingvarsson PK, Street NR
Physiol Plant 176 (5) e14511 [2024-09-16; online 2024-09-16]
PubMed DOI Crossref
An Atlas of Accessible Chromatin in Advanced Prostate Cancer Reveals the Epigenetic Evolution during Tumor Progression.
Shrestha R, Chesner LN, Zhang M, ..., Quigley DA, Feng FY
Cancer Res. 84 (18) 3086-3100 [2024-09-16; online 2024-07-11]
Arian Lundberg DDLS Fellow
PubMed DOI Crossref
Maternal pre-pregnancy BMI influences the associations between bisphenol and phthalate exposures and maternal weight changes and fat accumulation.
Irvine N, Bell RC, Subhan FB, ..., England-Mason G, APrON Study Team
Environ. Res. 257 (-) 119276 [2024-09-15; online 2024-06-01]
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The CHCHD2-CHCHD10 protein complex is modulated by mitochondrial dysfunction and alters lipid homeostasis in the mouse brain
Gerlach J, Pireddu P, Zhang X, ..., Svenningsson P, Filograna R
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Single cell transcriptome sequencing of fresh and cryopreserved bronchoalveolar lavage cells
Kolosenko I, Bonatti M, Wagner N, ..., Runold M, Wheelock ÅM
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Sequence variants influencing the regulation of serum IgG subclass levels.
Olafsdottir TA, Thorleifsson G, Lopez de Lapuente Portilla A, ..., Nilsson B, Stefansson K
Nat Commun 15 (1) 8054 [2024-09-14; online 2024-09-14]
Abhishek Niroula DDLS Fellow
DOI Crossref
Nasal transcriptomic profiling reveals distinct patterns in Type 2 Asthma
Merid SK, Hernandez-Pacheco N, Björkander S, ..., Koppelman GH, Melén E
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Feasibility of miRNA Detection in Particles in Exhaled Air (PExA) using a multiplexed RT-PCR Method
Bonatti M, Ezerskyte M, Lindberg P, Kolosenko I, Wheelock ÅM
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Cigarette smoking, but not snuff usage, is associated with a systemic inflammatory profile in young adults
Björkander S, Klevebro S, Hernandez-Pacheco N, ..., Bergström A, Melén E
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Characteristics of U-BIOPRED endotypes from multi-omics integration of 24 high-dimensional/throughput data
Zounemat-Kermani N, Li CX, Bonatti M, ..., Chung KF, Wheelock ÅM
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Biomarkers in ICU-treated Covid-19 patients 4 and 10 months after discharge: evidence for persistent inflammation and remodeling
Kalafatis D, Björnson M, Kistner A, ..., Westergren-Thorsson G, Sköld M
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PubMed DOI Crossref
Microbial dietary preference and interactions affect the export of lipids to the deep ocean.
Behrendt L, Alcolombri U, Hunter JE, ..., Stocker R, Van Mooy BAS
Science (New York, N.Y.) 385 (6714) eaab2661 [2024-09-13; online 2024-09-13]
Lars Behrendt SciLifeLab Fellow
PubMed DOI Crossref
Exposure of Colon-Derived Epithelial Monolayers to Fecal Luminal Factors from Patients with Colon Cancer and Ulcerative Colitis Results in Distinct Gene Expression Patterns.
Magnusson MK, Bas Forsberg A, Verveda A, ..., Simrén M, Öhman L
Int J Mol Sci 25 (18) - [2024-09-13; online 2024-09-13]
PubMed DOI Crossref
Discovery of a 6-Aminobenzo[b]thiophene 1,1-Dioxide Derivative (K2071) with a Signal Transducer and Activator of Transcription 3 Inhibitory, Antimitotic, and Senotherapeutic Activities.
Oleksak P, Rysanek D, Vancurova M, ..., Musilek K, Hodny Z
ACS pharmacology & translational science 7 (9) 2755-2783 [2024-09-13; online 2024-08-12]
DOI Crossref
Multi-tissue network analysis reveals the effect of JNK inhibition on dietary sucrose-induced metabolic dysfunction in rats
Yang H, Zhang C, Kim W, ..., Turkez H, Mardinoglu A
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Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Chromosome-level genome assembly of the morabine grasshopper Vandiemenella viatica19.
Li X, Jayaprasad S, Einarsdottir E, ..., Kawakami T, Palacios-Gimenez OM
Sci Data 11 (1) 997 [2024-09-12; online 2024-09-12]
PubMed DOI Crossref
Degradation of PET microplastic particles to monomers in human serum by PETase.
Lopez-Lorenzo X, Hueting D, Bosshard E, Syrén PO
Faraday Discuss 252 (0) 387-402 [2024-09-11; online 2024-09-11]
PubMed DOI Crossref
Control of bacterial cell wall autolysins by peptidoglycan crosslinking mode.
Alvarez L, Hernandez SB, Torrens G, ..., Dörr T, Cava F
Nat Commun 15 (1) 7937 [2024-09-11; online 2024-09-11]
PubMed DOI Crossref
Aging is associated with functional and molecular changes in distinct hematopoietic stem cell subsets.
Su TY, Hauenstein J, Somuncular E, ..., Månsson R, Luc S
Nat Commun 15 (1) 7966 [2024-09-11; online 2024-09-11]
DOI Crossref
Peer Review Report For: Facilitating accessible, rapid, and appropriate processing of ancient metagenomic data with AMDirT [version 2; peer review: 1 approved, 3 approved with reservations]
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Inherited human RelB deficiency impairs innate and adaptive immunity to infection.
Le Voyer T, Maglorius Renkilaraj MRL, Moriya K, ..., Tangye SG, Puel A
Proc. Natl. Acad. Sci. U.S.A. 121 (37) e2321794121 [2024-09-10; online 2024-09-04]
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Epigenetic regulation of cell state by H2AFY governs immunogenicity in high-risk neuroblastoma.
Nagarajan D, Parracho RT, Corujo D, ..., Buschbeck M, Mao Y
J. Clin. Invest. 134 (21) - [2024-09-10; online 2024-09-10]
SciLifeLab Fellow Yumeng Mao
PubMed DOI Crossref
Automated Image-Based Fluorescence Screening of Mitochondrial Membrane Potential in Daphnia magna: An Advanced Ecotoxicological Testing Tool.
Abele C, Perez A, Höglund A, ..., Breitholtz M, Karlsson O
Environ. Sci. Technol. 58 (36) 15926-15937 [2024-09-10; online 2024-08-27]
Oskar Karlsson SciLifeLab Fellow
PubMed DOI Crossref
Resolution of ribosomal stalling by EF-P and ABCF ATPases YfmR and YkpA/YbiT.
Takada H, Fujiwara K, Atkinson GC, Chiba S, Hauryliuk V
Nucleic Acids Res. 52 (16) 9854-9866 [2024-09-09; online 2024-06-29]
PubMed DOI Crossref
Loss of Lamin A leads to the nuclear translocation of AGO2 and compromised RNA interference.
Lobo V, Nowak I, Fernandez C, ..., Angeletti D, Sarshad AA
Nucleic Acids Res. 52 (16) 9917-9935 [2024-09-09; online 2024-07-12]
PubMed DOI Crossref
Long-term longitudinal analysis of 4,187 participants reveals insights into determinants of clonal hematopoiesis.
Uddin MM, Saadatagah S, Niroula A, ..., Ballantyne CM, Natarajan P
Nat Commun 15 (1) 7858 [2024-09-09; online 2024-09-09]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
Transient colonizing microbes promote gut dysbiosis and functional impairment.
Lee S, Meslier V, Bidkhori G, ..., Uhlen M, Shoaie S
NPJ Biofilms Microbiomes 10 (1) 80 [2024-09-08; online 2024-09-08]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
DOI Crossref
Bacterial transcriptional repressor NrdR – a flexible multifactorial nucleotide sensor
Rozman Grinberg I, Bimaï O, Shahid S, ..., Sjöberg BM, Logan DT
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DOI Crossref
Resolving the conformational ensemble of a membrane protein by integrating small-angle scattering with AlphaFold
Lidbrink SE, Howard R, Haloi N, Lindahl E
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DOI Crossref
The protein domains of vertebrate species in which selection is more effective have greater intrinsic structural disorder
Weibel CA, Wheeler AL, James JE, ..., McShea H, Masel J
Elife 12 (-) - [2024-09-06; online 2024-09-06]
DDLS Fellow Jennifer James
PubMed DOI Crossref
Hyper-recombination in ribosomal DNA is driven by long-range resection-independent RAD51 accumulation.
Gál Z, Boukoura S, Oxe KC, ..., Luo Y, Larsen DH
Nat Commun 15 (1) 7797 [2024-09-06; online 2024-09-06]
PubMed DOI Crossref
Divergent mechanisms of steroid inhibition in the human ρ1 GABAA receptor.
Fan C, Cowgill J, Howard RJ, Lindahl E
Nat Commun 15 (1) 7795 [2024-09-06; online 2024-09-06]
PubMed DOI Crossref
Defining the Soluble and Extracellular Vesicle Protein Compartments of Plasma Using In-Depth Mass Spectrometry-Based Proteomics.
Sharma N, Angori S, Sandberg A, ..., Eriksson H, Pernemalm M
J. Proteome Res. 23 (9) 4114-4127 [2024-09-06; online 2024-08-14]
DOI Crossref
Comprehensive analysis of the RBP regulome reveals functional modules and drug candidates in liver cancer
Garbulowski M, Mosca R, Gallardo-Dodd CJ, Kutter C, Sonnhammer ELL
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Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Genetic ablation of adhesion ligands mitigates rejection of allogeneic cellular immunotherapies.
Hammer Q, Perica K, Mbofung RM, ..., Sadelain M, Malmberg KJ
Cell Stem Cell 31 (9) 1376-1386.e8 [2024-09-05; online 2024-07-08]
PubMed DOI Crossref
Exploring the structural landscape of DNA maintenance proteins.
Schou KB, Mandacaru S, Tahir M, ..., Papaleo E, Bartek J
Nat Commun 15 (1) 7748 [2024-09-05; online 2024-09-05]
PubMed DOI Crossref
Development of a three-dimensional scoring model for the assessment of continuous glucose monitoring data in type 1 diabetes.
Dawnbringer J, Hill H, Lundgren M, ..., Carlsson PO, Espes D
BMJ Open Diabetes Res Care 12 (4) - [2024-09-05; online 2024-09-05]
Daniel Espes SciLifeLab Fellow
DOI Crossref
Deep learning segmentation model produces accurate biodiversity predictions at 10 m spatial resolution
Andermann T, Häggmark J, Olsson P, Högström A
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DDLS Fellow Tobias Andermann
PubMed DOI Crossref
Diversity in Recombination Hotspot Characteristics and Gene Structure Shape Fine-Scale Recombination Patterns in Plant Genomes.
Brazier T, Glémin S
Mol. Biol. Evol. 41 (9) - [2024-09-04; online 2024-09-20]
PubMed DOI Crossref
Discovery of a novel inhibitor of macropinocytosis with antiviral activity.
Porebski B, Christ W, Corman A, ..., Hühn D, Fernandez-Capetillo O
Mol. Ther. 32 (9) 3012-3024 [2024-09-04; online 2024-07-02]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Caveolin assemblies displace one bilayer leaflet to organize and bend membranes.
Doktorova M, Daum S, Ebenhan J, ..., Kenworthy AK, Levental I
bioRxiv - (-) - [2024-09-04; online 2024-09-04]
DDLS Fellow Milka Doktorova
PubMed DOI Crossref
The Oxidation of Electron-Rich Arenes Using a H2O2-Proline System.
Chetty LC, Kruger HG, Arvidsson PI, ..., Govender T, Naicker T
ACS Omega 9 (35) 37155-37162 [2024-09-03; online 2024-08-22]
PubMed DOI Crossref
Regional distribution of mechanical strain and macrophage-associated lung inflammation after ventilator-induced lung injury: an experimental study.
Liggieri F, Chiodaroli E, Pellegrini M, ..., Eriksson O, Perchiazzi G
Intensive Care Med Exp 12 (1) 77 [2024-09-03; online 2024-09-03]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
Nationwide prospective audit for the evaluation of appendicitis risk prediction models in adults: right iliac fossa treatment (RIFT)-Turkey.
Yalcinkaya A, Yalcinkaya A, Balci B, ..., Leventoglu S, RIFT TURKEY Study Collaboration
BJS Open 8 (5) - [2024-09-03; online 2024-10-09]
PubMed DOI Crossref
Multi-ancestry polygenic risk scores for venous thromboembolism.
Jee YH, Thibord F, Dominguez A, ..., Kraft P, INVENT Consortium
Hum. Mol. Genet. 33 (18) 1584-1591 [2024-09-03; online 2024-06-16]
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Cryo-EM images of phase-separated lipid bilayer vesicles analyzed with a machine-learning approach.
Sharma KD, Doktorova M, Waxham MN, Heberle FA
Biophys. J. 123 (17) 2877-2891 [2024-09-03; online 2024-04-30]
DDLS Fellow Milka Doktorova
PubMed DOI Crossref
Protective Non-neutralizing anti-N-terminal Domain mAb Maintains Fc-mediated Function against SARS-COV-2 Variants up to BA.2.86-JN.1 with Superfluous In Vivo Protection against JN.1 Due to Attenuated Virulence.
Izadi A, Godzwon M, Söderlund Strand A, ..., Ohlin M, Nordenfelt P
J. Immunol. 213 (5) 678-689 [2024-09-01; online 2024-07-17]
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Novel Calcium Phosphate Promotes Interbody Bony Fusion in a Porcine Anterior Cervical Discectomy and Fusion Model.
Östman M, Försth P, Hedenqvist P, ..., Höglund O, Forterre F
Spine (Phila Pa 1976) 49 (17) 1179-1186 [2024-09-01; online 2024-01-12]
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ECCB2024: The 23rd European Conference on Computational Biology.
Kukkonen-Macchi A, Hautaniemi S, Heil KF, ..., Nyrönen TH, Elo LL
Bioinformatics 40 (Suppl 2) ii1-ii3 [2024-09-01; online 2024-09-04]
DOI Crossref
Convergent and lineage-specific genomic changes shape adaptations in sugar-consuming birds
Osipova E, Ko MC, Petricek KM, ..., Hiller M, Sackton TB
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PubMed DOI Crossref
quantms: a cloud-based pipeline for quantitative proteomics enables the reanalysis of public proteomics data.
Dai C, Pfeuffer J, Wang H, ..., Kohlbacher O, Perez-Riverol Y
Nat. Methods 21 (9) 1603-1607 [2024-09-00; online 2024-07-04]
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Unveiling structural features, chemical reactivity, and bioactivity of a newly synthesized purine derivative through crystallography and computational approaches
Abad N, Buhlak S, Hajji M, ..., Turkez H, Mardinoglu A
Journal of Molecular Structure 1311 (-) 138400 [2024-09-00; online 2024-09-00]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
The one-carbon metabolic enzyme MTHFD2 promotes resection and homologous recombination after ionizing radiation.
Marttila P, Bonagas N, Chalkiadaki C, ..., Mortusewicz O, Helleday T
Mol Oncol 18 (9) 2179-2195 [2024-09-00; online 2024-03-27]
PubMed DOI Crossref
Systems genetic analysis of lignin biosynthesis in Populus tremula.
Luomaranta M, Grones C, Choudhary S, ..., Street NR, Tuominen H
New Phytol. 243 (6) 2157-2174 [2024-09-00; online 2024-07-28]
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Synthesis, spectroscopic characterization, DFT and molecular docking of N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl) naphthalene-1-sulfonamide derivatives
Ashraf S, Iqbal S, Sebhaoui J, ..., Turkez H, Mardinoglu A
Journal of Molecular Structure 1312 (-) 138470 [2024-09-00; online 2024-09-00]
Adil Mardinoglu SciLifeLab Fellow
PubMed DOI Crossref
Spinocerebellar ataxia type 4 is caused by a GGC expansion in the ZFHX3 gene and is associated with prominent dysautonomia and motor neuron signs.
Paucar M, Nilsson D, Engvall M, ..., Wedell A, Svenningsson P
J. Intern. Med. 296 (3) 234-248 [2024-09-00; online 2024-07-07]
PubMed DOI Crossref
Spatial metatranscriptomics resolves host-bacteria-fungi interactomes.
Saarenpää S, Shalev O, Ashkenazy H, ..., Weigel D, Giacomello S
Nat. Biotechnol. 42 (9) 1384-1393 [2024-09-00; online 2023-11-20]
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Spatial landscapes of cancers: insights and opportunities.
Chen J, Larsson L, Swarbrick A, Lundeberg J
Nat Rev Clin Oncol 21 (9) 660-674 [2024-09-00; online 2024-07-23]
PubMed DOI Crossref
Spatial host-microbiome sequencing reveals niches in the mouse gut.
Lötstedt B, Stražar M, Xavier R, Regev A, Vickovic S
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Oskar Karlsson SciLifeLab Fellow
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Theodoropoulou E, Pierozan P, Höglund A, Karlsson O
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Oskar Karlsson SciLifeLab Fellow
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OC01.04: *AI‐driven ultrasound detection of ovarian cancer that generalises: an international multicentre validation study
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Ultrasound in Obstet & Gyne 64 (S1) 2-2 [2024-09-00; online 2024-09-09]
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Microsecond time-resolved X-ray scattering by utilizing MHz repetition rate at second-generation XFELs.
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Major cardiovascular events and death in parents of children with type 1 diabetes: a register-based matched cohort study in Sweden.
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Location matters: mapping antigen receptors within tissues.
Lin Q, Thrane K, Engblom C
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Ironing out protein synthesis: METTL17 is an Fe-S cluster checkpoint for mitochondrial translation
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Biochim Biophys Acta Bioenerg 1865 (-) 149421 [2024-09-00; online 2024-09-00]
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Increased levels of thymidine kinase 1 in malignant cell-derived extracellular vesicles.
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Immune system adaptation during gender-affirming testosterone treatment.
Lakshmikanth T, Consiglio C, Sardh F, ..., Landegren N, Brodin P
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Camila Consiglio DDLS Fellow
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HL7 Fast Healthcare Interoperability Resources (HL7 FHIR) in digital healthcare ecosystems for chronic disease management: Scoping review.
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GeneSPIDER2: large scale GRN simulation and benchmarking with perturbed single-cell data.
Garbulowski M, Hillerton T, Morgan D, ..., Nordling TEM, Sonnhammer ELL
NAR Genomics and Bioinformatics 6 (3) lqae121 [2024-09-00; online 2024-09-18]
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GPX4 transcriptionally promotes liver cancer metastasis via GRHL3/PTEN/PI3K/AKT axis.
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Estrogen receptor beta expression and role in cancers.
Monteiro FL, Stepanauskaite L, Archer A, Williams C
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Dantrolene corrects cellular disease features of Darier disease and may be a novel treatment.
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EMBO Mol Med 16 (9) 1986-2001 [2024-09-00; online 2024-07-26]
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Contemporary intergeneric hybridization and backcrossing among birds-of-paradise.
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Consistency of a clinical decision support system with molecular tumour board recommendations for tumour sequencing-guided treatment of pancreatic cancer.
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ESMO Gastrointestinal Oncology 5 (-) 100070 [2024-09-00; online 2024-06-19]
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Zheng T, Kotol D, Sjöberg R, ..., Edfors F, Mulder J
Glia 72 (9) 1590-1603 [2024-09-00; online 2024-06-10]
DDLS Fellow Fredrik Edfors
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Cancer Med 13 (18) e70255 [2024-09-00; online 2024-09-24]
Oskar Karlsson SciLifeLab Fellow
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Sajkowska JJ, Tsang CH, Kozielewicz P
SLAS Discov 29 (6) 100174 [2024-09-00; online 2024-07-29]
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AI-based selection of individuals for supplemental MRI in population-based breast cancer screening: the randomized ScreenTrustMRI trial.
Salim M, Liu Y, Sorkhei M, ..., Smith K, Strand F
Nat. Med. 30 (9) 2623-2630 [2024-09-00; online 2024-07-08]
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A challenge to the expected: Lack of longitudinal associations between the early caregiving environment, executive functions in toddlerhood, and self-regulation at 6 years.
Jónsdóttir LK, Forslund T, Frick MA, ..., Heeman EJ, Brocki KC
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989O Novel gene therapy in advanced solid malignancies: A phase I/II clinical trial
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Ann Oncol 35 (-) S674 [2024-09-00; online 2024-09-00]
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Making Multiplexed Imaging Flexible: Combining Essential Markers With Established Antibody Panels.
Deen AJ, Thorsson J, O'Roberts EM, ..., Oses C, Stadler C
J. Histochem. Cytochem. 72 (8-9) 517-544 [2024-08-31; online 2024-08-31]
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Olsen TK, Otte J, Mei S, ..., Kharchenko PV, Baryawno N
Mol Cancer 23 (1) 180 [2024-08-31; online 2024-08-31]
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Tiemann JKS, Szczuka M, Bouarroudj L, ..., Chavent M, Poulain P
Elife 12 (-) - [2024-08-30; online 2024-08-30]
Lucie Delemotte SciLifeLab Fellow
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MDverse, shedding light on the dark matter of molecular dynamics simulations
Tiemann JK, Szczuka M, Bouarroudj L, ..., Chavent M, Poulain P
Elife 12 (-) - [2024-08-30; online 2024-08-30]
Lucie Delemotte SciLifeLab Fellow
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Rodríguez-Varela R, Yaka R, Pochon Z, ..., Azkarate A, Götherström A
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Author response: MDverse, shedding light on the dark matter of molecular dynamics simulations
Tiemann JK, Szczuka M, Bouarroudj L, ..., Chavent M, Poulain P
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Lucie Delemotte SciLifeLab Fellow
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Rubin CJ, Hodge M, Naboulsi R, ..., Lindgren G, Andersson L
Nat Commun 15 (1) 7510 [2024-08-29; online 2024-08-29]
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A charged tail on anti-α-Synuclein antibodies does not enhance their affinity to α-Synuclein fibrils.
Petersen I, Godec A, Ranjbarian F, ..., Mirabello C, Hultqvist G
PLoS ONE 19 (8) e0308521 [2024-08-29; online 2024-08-29]
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Özel F, Stratmann M, Papadopoulos FC, Rüegg J, Bornehag CG
PLoS ONE 19 (8) e0308605 [2024-08-28; online 2024-08-28]
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Nagy Á, Abouzayed A, Kanellopoulos P, ..., Orlova A, Eriksson Karlström A
ACS Omega 9 (34) 36122-36133 [2024-08-27; online 2024-08-15]
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Epigenetic insights into GABAergic development in Dravet Syndrome iPSC and therapeutic implications.
Schuster J, Lu X, Dang Y, ..., Dahl N, Chen X
Elife 12 (-) - [2024-08-27; online 2024-08-27]
DOI Crossref
Epigenetic insights into GABAergic development in Dravet Syndrome iPSC and therapeutic implications
Schuster J, Lu X, Dang Y, ..., Dahl N, Chen X
Elife 12 (-) - [2024-08-27; online 2024-08-27]
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Disentangling the riddle of systemic lupus erythematosus with antiphospholipid syndrome: blood transcriptome analysis reveals a less-pronounced IFN-signature and distinct molecular profiles in venous versus arterial events.
Nikolopoulos D, Loukogiannaki C, Sentis G, ..., Filia A, Boumpas DT
Ann. Rheum. Dis. 83 (9) 1132-1143 [2024-08-27; online 2024-08-27]
PubMed DOI Crossref
Structure prediction of alternative protein conformations.
Bryant P, Noé F
Nat Commun 15 (1) 7328 [2024-08-26; online 2024-08-26]
DDLS Fellow Patrick Bryant
PubMed DOI Crossref
Single-cell transcriptomics reveal transcriptional programs underlying male and female cell fate during Plasmodium falciparum gametocytogenesis.
Mohammed M, Dziedziech A, Macedo D, ..., Henriksson J, Ankarklev J
Nat Commun 15 (1) 7177 [2024-08-26; online 2024-08-26]
SciLifeLab Fellow Tanja Slotte
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SHP-1 Variants Broaden the Understanding of pH-Dependent Activities in Protein Tyrosine Phosphatases.
Shen R, Brownless AR, Alansson N, ..., Kamerlin SCL, Hengge AC
JACS Au 4 (8) 2874-2885 [2024-08-26; online 2024-07-17]
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Mechanistic modeling of cell viability assays with in silico lineage tracing.
Mutsuddy A, Huggins JR, Amrit A, ..., Calhoun JC, Birtwistle MR
bioRxiv - (-) - [2024-08-26; online 2024-08-26]
Cemal Erdem DDLS Fellow
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BaTwa populations from Zambia retain ancestry of past hunter-gatherer groups.
Breton G, Barham L, Mudenda G, ..., Schlebusch CM, Jakobsson M
Nat Commun 15 (1) 7307 [2024-08-24; online 2024-08-24]
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ΔNp63 bookmarks and creates an accessible epigenetic environment for TGFβ-induced cancer cell stemness and invasiveness.
Vasilaki E, Bai Y, Ali MM, ..., Moustakas A, Heldin CH
Cell Commun. Signal 22 (1) 411 [2024-08-23; online 2024-08-23]
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Massively parallel analysis of single-molecule dynamics on next-generation sequencing chips.
Aguirre Rivera J, Mao G, Sabantsev A, ..., Jinek M, Deindl S
Science (New York, N.Y.) 385 (6711) 892-898 [2024-08-23; online 2024-08-22]
SciLifeLab Fellow Sebastian Deindl
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Comparing Lipinskis Rule of 5 and Machine Learning Based Prediction of Fraction Absorbed for Assessing Oral Absorption in Humans
Fagerholm U, Hellberg S, Alvarsson J, Ekmefjord M, Spjuth O
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Hydrazide-based reactive matrices for the sensitive detection of aldehydes and ketones by MALDI mass spectrometry imaging.
Lodén H, Schembri LS, Nilsson A, ..., Odell LR, Andrén PE
Chem. Commun. (Camb.) 60 (69) 9238-9241 [2024-08-22; online 2024-08-22]
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Shabestary K, Klamt S, Link H, ..., Steuer R, Hudson EP
Nat Rev Bioeng 2 (12) 1039-1055 [2024-08-22; online 2024-08-22]
Paul Hudson SciLifeLab Fellow
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Zfp697 is an RNA-binding protein that regulates skeletal muscle inflammation and remodeling.
Correia JC, Jannig PR, Gosztyla ML, ..., Yeo GW, Ruas JL
Proc. Natl. Acad. Sci. U.S.A. 121 (34) e2319724121 [2024-08-20; online 2024-08-14]
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The involvement of cyclotides in the heavy metal tolerance of Viola spp.
Sychta K, Słomka A, Shariatgorji R, ..., Göransson U, Slazak B
Sci Rep 14 (1) 19306 [2024-08-20; online 2024-08-20]
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Size-related variability of oxygen consumption rates in individual human hepatic cells.
Botte E, Cui Y, Magliaro C, ..., Behrendt L, Ahluwalia A
Lab Chip 24 (17) 4128-4137 [2024-08-20; online 2024-08-20]
Lars Behrendt SciLifeLab Fellow
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Pardo-Avila F, Kudva R, Levitt M, von Heijne G
bioRxiv - (-) - [2024-08-20; online 2024-08-20]
PubMed DOI Crossref
Quantification of membrane fluidity in bacteria using TIR-FCS.
Barbotin A, Billaudeau C, Sezgin E, Carballido-López R
Biophys. J. 123 (16) 2484-2495 [2024-08-20; online 2024-06-13]
Erdinc Sezgin SciLifeLab Fellow
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Multi-layered dosage compensation of the avian Z chromosome
Papanicolaou N, Lentini A, Wettersten S, ..., Wright D, Reinius B
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Antonio Lentini DDLS Fellow
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Gel-Assisted Proteome Position Integral Shift Assay Returns Molecular Weight to Shotgun Proteomics and Identifies Caspase 3 Substrates.
Meng Z, Saei AA, Gharibi H, ..., Gaetani M, Zubarev RA
Anal. Chem. 96 (33) 13533-13541 [2024-08-20; online 2024-08-07]
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Bartels M, Chibaudel B, Dienstmann R, ..., O'Kane G, Pruneri G
Cancers (Basel) 16 (16) - [2024-08-20; online 2024-08-20]
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Detection of protein-protein interactions by bio-orthogonal fluorogenic proximity probes
Torell A, Larsson NA, Phillipson S, Odell LR, Fürth D
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Daniel Fürth SciLifeLab Fellow
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DNA methylation patterns contribute to changes of cellular differentiation pathways in leukocytes with LOY from patients with Alzheimer’s disease
Jąkalski M, Bruhn-Olszewska B, Rychlicka-Buniowska E, ..., Ingelsson M, Dumanski JP
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Therapeutic application of extracellular vesicular EGFR isoform D as a co-drug to target squamous cell cancers with tyrosine kinase inhibitors.
Toh SY, Leong HS, Chong FT, ..., Tan DSW, Iyer NG
Dev. Cell 59 (16) 2189-2202.e8 [2024-08-19; online 2024-07-31]
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Sleep maintains excitatory synapse diversity in the cortex and hippocampus.
Koukaroudi D, Qiu Z, Fransén E, ..., Seibt J, Grant SGN
Curr. Biol. 34 (16) 3836-3843.e5 [2024-08-19; online 2024-08-02]
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Improved Detection of Drug-Induced Liver Injury by Integrating Predicted In Vivo and In Vitro Data.
Seal S, Williams D, Hosseini-Gerami L, ..., Spjuth O, Bender A
Chem. Res. Toxicol. 37 (8) 1290-1305 [2024-08-19; online 2024-07-09]
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Host-pathogen interactions in the Plasmodium-infected mouse liver at spatial and single-cell resolution.
Hildebrandt F, Iturritza MU, Zwicker C, ..., Lundeberg J, Ankarklev J
Nat Commun 15 (1) 7105 [2024-08-19; online 2024-08-19]
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Defining Vaginal Community Dynamics: daily microbiome transitions, the role of menstruation, bacteriophages, and bacterial genes.
Hugerth LW, Krog MC, Vomstein K, ..., Nielsen HS, Schuppe-Koistinen I
Microbiome 12 (1) 153 [2024-08-19; online 2024-08-19]
DDLS Fellow Luisa Hugerth
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A roadmap to the molecular human linking multiomics with population traits and diabetes subtypes.
Halama A, Zaghlool S, Thareja G, ..., Schmidt F, Suhre K
Nat Commun 15 (1) 7111 [2024-08-19; online 2024-08-19]
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CDK12 controls transcription at damaged genes and prevents MYC-induced transcription-replication conflicts.
Curti L, Rohban S, Bianchi N, ..., Parazzoli D, Campaner S
Nat Commun 15 (1) 7100 [2024-08-18; online 2024-08-18]
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Origin, structure, and composition of the spider major ampullate silk fiber revealed by genomics, proteomics, and single-cell and spatial transcriptomics.
Sonavane S, Hassan S, Chatterjee U, ..., Reimegård J, Rising A
Sci Adv 10 (33) eadn0597 [2024-08-16; online 2024-08-14]
PubMed DOI Crossref
Open-source, high-throughput targeted in situ transcriptomics for developmental and tissue biology.
Lee H, Langseth CM, Salas SM, ..., Grillo M, Nilsson M
Development 151 (16) - [2024-08-15; online 2024-08-29]
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In sickness and health - a questionnaire based study regarding immune mediated diseases and neoplasia in Swedish Nova Scotia Duck Tolling Retrievers.
Nilsson M, Kozyrev SV, Lindblad-Toh K, Rönnberg H, Hansson-Hamlin H
Acta Vet Scand 66 (1) 39 [2024-08-15; online 2024-08-15]
DOI Crossref
EMhub: a web platform for data management and on-the-fly processing in scientific facilities
De la Rosa-Trevin JM, Sharov G, Fleischmann S, ..., Fernandez IS, Carroni M
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Chemical exposomics in plasma from Swedish women and associations with breast cancer risk factors
Edlund J, Sdougkou K, Papazian S, ..., Martin J, Harlid S
ISEE Conference Abstracts 2024 (1) - [2024-08-15; online 2024-08-15]
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Erb IK, Suarez C, Frank EM, ..., Lindberg E, Paul CJ
FEMS Microbes 5 (-) xtae024 [2024-08-14; online 2024-08-14]
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Distinct bacterial and protist plankton diversity dynamics uncovered through DNA-based monitoring in the Baltic Sea area
Jurdzinski KT, Latz MA, Torstensson A, ..., Karlson B, Andersson AF
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Sun W-S, Torrens G, Ter Beek J, Cava F, Berntsson RP-A
MBio 15 (8) e0048824 [2024-08-14; online 2024-06-28]
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The Association of Cardiometabolic, Diet and Lifestyle Parameters With Plasma Glucagon-like Peptide-1: An IMI DIRECT Study.
Eriksen R, White MC, Dawed AY, ..., Frost G, Pearson ER
J. Clin. Endocrinol. Metab. 109 (9) e1697-e1707 [2024-08-13; online 2024-04-30]
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Screening persistent organic pollutants for effects on testosterone and estrogen synthesis at human-relevant concentrations using H295R cells in 96-well plates.
Strand D, Nylander E, Höglund A, ..., Martin JW, Karlsson O
Cell Biol Toxicol 40 (1) 69 [2024-08-13; online 2024-08-13]
Oskar Karlsson SciLifeLab Fellow
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Reviewer #2 (Public Review): Epigenetic insights into GABAergic development in Dravet Syndrome iPSC and therapeutic implications
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DOI Crossref
One-Pot Time-Induced Proteome Integral Solubility Alteration (OPTI-PISA) assay for automated and sensitive drug target identification
Meng Z, Saei AA, Lyu H, Gaetani M, Zubarev RA
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Merging Multi-OMICs with Proteome Integral Solubility Alteration Unveils Antibiotic Mode of Action
Maity R, Zhang X, Liberati FR, ..., Aínsa JA, Sancho J
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PubMed DOI Crossref
Genomic and transcriptomic features of androgen receptor signaling inhibitor resistance in metastatic castration-resistant prostate cancer.
Zhu X, Farsh T, Vis D, ..., van der Heijden MS, Feng FY
J. Clin. Invest. 134 (19) - [2024-08-13; online 2024-08-13]
Arian Lundberg DDLS Fellow
DOI Crossref
Epigenetic insights into GABAergic development in Dravet Syndrome iPSC and therapeutic implications
Schuster J, Lu X, Dang Y, ..., Dahl N, Chen X
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DOI Crossref
Author response: Merging Multi-OMICs with Proteome Integral Solubility Alteration Unveils Antibiotic Mode of Action
Maity R, Zhang X, Liberati FR, ..., Aínsa JA, Sancho J
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DOI Crossref
Author response: Epigenetic insights into GABAergic development in Dravet Syndrome iPSC and therapeutic implications
Schuster J, Lu X, Dang Y, ..., Dahl N, Chen X
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READv2: advanced and user-friendly detection of biological relatedness in archaeogenomics.
Alaçamlı E, Naidoo T, Güler MN, ..., Malmström H, Günther T
Genome Biol. 25 (1) 216 [2024-08-12; online 2024-08-12]
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Four decades of research on Viktor Mutt’s neuropeptides with focus on galanin
Hökfelt T, Barde S, Zhong W, Xu ZQD, Alberts P
PEAS 73 (3) 170-192 [2024-08-12; online 2024-08-12]
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Bacterial ecology and evolution converge on seasonal and decadal scales.
Rohwer RR, Kirkpatrick M, Garcia SL, ..., McMahon KD, Baker BJ
bioRxiv - (-) - [2024-08-12; online 2024-08-12]
Sarahi Garcia SciLifeLab Fellow
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A role for the S4-domain containing protein YlmH in ribosome-associated quality control in Bacillus subtilis.
Takada H, Paternoga H, Fujiwara K, ..., Wilson DN, Hauryliuk V
Nucleic Acids Res. 52 (14) 8483-8499 [2024-08-12; online 2024-05-30]
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Sex-Specific Associations between Prenatal Exposure to Bisphenols and Phthalates and Infant Epigenetic Age Acceleration.
England-Mason G, Merrill SM, Liu J, ..., Kobor MS, Dewey D
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Extensively acquired antimicrobial resistant bacteria restructure the individual microbial community in post-antibiotic conditions
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Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
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Association of polygenic scores for autism with volumetric MRI phenotypes in cerebellum and brainstem in adults.
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Applying Spatial Metabolomics To Investigate Age- and Drug-Induced Neurochemical Changes.
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β-Carboline-based light and pH dual stimuli-responsive ion transporters induce cancer cell death.
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ThermoTargetMiner as a proteome integral solubility alteration target database for prospective drugs against lung cancer
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Systematic review and feasibility study on pre-analytical factors and genomic analyses on archival formalin-fixed paraffin-embedded breast cancer tissue.
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Hydrogen production by a fully de novo enzyme.
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Allosteric inhibition of CFTR gating by CFTRinh-172 binding in the pore.
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Integrating Natural and Engineered Genetic Variation to Decode Regulatory Influence on Blood Traits
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Deciphering the genetics and mechanisms of predisposition to multiple myeloma.
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Nat Commun 15 (1) 6644 [2024-08-05; online 2024-08-05]
Abhishek Niroula DDLS Fellow
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A multiscale model of striatum microcircuit dynamics
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A multiscale model of striatum microcircuit dynamics
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Multiplexed mapping of the interactome of GPCRs with receptor activity-modifying proteins.
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A genome-wide genetic screen identified targets for destabilizing the parasitophorous vacuole of Chlamydia trachomatis
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Understanding the interplay between dNTP metabolism and genome stability in cancer.
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Oral administration of CXCL12-expressing Limosilactobacillus reuteri improves colitis by local immunomodulatory actions in preclinical models.
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GPCR Function in Autophagy Control: A Systematic Approach of Chemical Intervention.
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Effects of oral contraceptives and menopausal hormone therapy on the risk of rheumatoid arthritis: a prospective cohort study.
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Rheumatology (Oxford) 63 (8) 2101-2108 [2024-08-01; online 2023-09-29]
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Ecological genomics in the Northern krill uncovers loci for local adaptation across ocean basins.
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The brittle star genome illuminates the genetic basis of animal appendage regeneration.
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Structure-based virtual screening of vast chemical space as a starting point for drug discovery.
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Andreas Luttens DDLS Fellow Jens Carlsson SciLifeLab Fellow
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SMYD5 methylation of rpL40 links ribosomal output to gastric cancer.
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Nature 632 (8025) 656-663 [2024-08-00; online 2024-07-24]
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Role of estrogen signaling in fibroblastic reticular cells for innate and adaptive immune responses in antigen-induced arthritis.
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Mechanistic screening of reproductive toxicity in a novel 3D testicular co-culture model shows significant impairments following exposure to low-dibutyl phthalate concentrations.
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Oskar Karlsson SciLifeLab Fellow
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Maternal exposure to bisphenols, phthalates, perfluoroalkyl acids, and trace elements and their associations with gestational diabetes mellitus in the APrON cohort.
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Mapping the Multiscale Proteomic Organization of Cellular and Disease Phenotypes.
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Mapping spatially resolved transcriptomes in human and mouse pulmonary fibrosis.
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Maculopathy and adult-onset ataxia in patients with biallelic MFSD8 variants.
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Integrated analyses highlight interactions between the three-dimensional genome and DNA, RNA and epigenomic alterations in metastatic prostate cancer.
Zhao SG, Bootsma M, Zhou S, ..., Lupien M, Feng FY
Nat. Genet. 56 (8) 1689-1700 [2024-08-00; online 2024-07-17]
Arian Lundberg DDLS Fellow
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Genotyping oral contraceptive users for venous thromboembolism risk.
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Am J Obstet Gynecol 231 (2) e80 [2024-08-00; online 2024-05-01]
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Exploring Paleogene Tibet's warm temperate environments through target enrichment and phylogenetic niche modelling of Himalayan spiny frogs (Paini, Dicroglossidae).
Hofmann S, Rödder D, Andermann T, ..., Schmidt J, Podsiadlowski L
Mol. Ecol. 33 (15) e17446 [2024-08-00; online 2024-07-01]
DDLS Fellow Tobias Andermann
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Epidemiological and environmental investigation of the 'big four' Vibrio species, 1994 to 2021: a Baltic Sea retrospective study.
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Euro Surveill 29 (32) - [2024-08-00; online 2024-08-09]
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Dominance between self-incompatibility alleles determines the mating system of Capsella allopolyploids.
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Direct presentation of inflammation-associated self-antigens by thymic innate-like T cells induces elimination of autoreactive CD8+ thymocytes.
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Nat. Immunol. 25 (8) 1367-1382 [2024-08-00; online 2024-07-11]
Patrick Sandoz SciLifeLab Fellow
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Development and implementation of assays to monitor human adenovirus F40/41 in wastewater: Trends preceding, during, and following the non-A-to-E hepatitis outbreak in Stockholm.
Perez-Zabaleta M, Williams C, Cetecioglu Z
Environ Int 190 (-) 108937 [2024-08-00; online 2024-08-05]
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Detection of transcriptome-wide microRNA-target interactions in single cells with agoTRIBE.
Sekar V, Mármol-Sánchez E, Kalogeropoulos P, ..., Biryukova I, Friedländer MR
Nat. Biotechnol. 42 (8) 1296-1302 [2024-08-00; online 2023-09-21]
Marc Friedländer SciLifeLab Fellow
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Combining VPS34 inhibitors with STING agonists enhances type I interferon signaling and anti-tumor efficacy.
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Mol Oncol 18 (8) 1904-1922 [2024-08-00; online 2024-03-20]
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BioImage.IO Chatbot: a community-driven AI assistant for integrative computational bioimaging.
Lei W, Fuster-Barceló C, Reder G, Muñoz-Barrutia A, Ouyang W
Nat. Methods 21 (8) 1368-1370 [2024-08-00; online 2024-08-10]
DDLS Fellow Wei Ouyang
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Artificial intelligence for high content imaging in drug discovery.
Carreras-Puigvert J, Spjuth O
Curr. Opin. Struct. Biol. 87 (-) 102842 [2024-08-00; online 2024-05-25]
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A suicidal and extensively disordered luciferase with a bright luminescence.
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Protein Sci. 33 (8) e5115 [2024-08-00; online 2024-07-18]
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A second space age spanning omics, platforms and medicine across orbits.
Mason CE, Green J, Adamopoulos KI, ..., Mateus J, Beheshti A
Nature 632 (8027) 995-1008 [2024-08-00; online 2024-06-11]
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A multiomic characterization of the leukemia cell line REH using short- and long-read sequencing.
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Life Sci. Alliance 7 (8) - [2024-08-00; online 2024-05-22]
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A Visual Environment for Data Driven Protein Modeling and Validation.
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IEEE Trans Vis Comput Graph 30 (8) 5063-5073 [2024-08-00; online 2024-07-01]
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Inhibition of IRAP Enhance the Expression of Pro-cognitive Markers Drebrin and MAP2 in Rat Primary Neuronal Cells
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Bacteria combine polar- and dispersed-growth to power cell elongation and wall width dynamics
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Genome-wide expression analysis in a Fabry disease human podocyte cell line.
Snanoudj S, Derambure C, Zhang C, ..., Bekri S, Tebani A
Heliyon 10 (14) e34357 [2024-07-30; online 2024-07-09]
Adil Mardinoglu SciLifeLab Fellow
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Enhancers regulate genes linked to severe and mild childhood asthma.
Akhter T, Mileti E, Kere MM, ..., Melén E, Daub CO
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Cryo-EM structures of ρ1 GABA A receptors with antagonist and agonist drugs
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Blood glucose outcomes of anti-retroviral therapy naïve Ugandan people with HIV with pre-diabetes mellitus initiated on dolutegravir for 48 weeks.
Mulindwa F, Schwarz JM, Brusselaers N, ..., Kiguba R, Castelnuovo B
BMC Infect Dis 24 (1) 746 [2024-07-29; online 2024-07-29]
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Helical superstructures between amyloid and collagen in cardiac fibrils from a patient with AL amyloidosis.
Schulte T, Chaves-Sanjuan A, Speranzini V, ..., Palladini G, Ricagno S
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Selective lysis of acute myeloid leukemia cells by CD34/CD3 bispecific antibody through the activation of γδ T-cells.
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Oncoimmunology 13 (1) 2379063 [2024-07-27; online 2024-07-27]
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OCT1 (SLC22A1) transporter kinetics and regulation in primary human hepatocyte 3D spheroids.
Mickols E, Meyer A, Handin N, ..., Karlgren M, Artursson P
Sci Rep 14 (1) 17334 [2024-07-27; online 2024-07-27]
Mikael Sellin SciLifeLab Fellow
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Large-scale proteomics reveals precise biomarkers for detection of ovarian cancer in symptomatic women.
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Sci Rep 14 (1) 17288 [2024-07-27; online 2024-07-27]
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Disparate and shared transcriptomic signatures associated with cortical atrophy in genetic bvFTD.
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Complex Polyploids: Origins, Genomic Composition, and Role of Introgressed Alleles.
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DDLS Fellow Jennifer James Pascal Milesi SciLifeLab Fellow
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Autoantibodies towards HFE and SYT5 in anti-neutrophil cytoplasm antibody-associated vasculitis relapse
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Adaptive Robust Learning using Latent Bernoulli Variables
Karakulev A, Zachariah D, Singh P
Proceedings of the 41st International Conference on Machine Learning, PMLR 235 (-) 23105-23122 [2024-07-27; online 2023-12-04]
Prashant Singh SciLifeLab Fellow
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Loss of the tumour suppressor LKB1/STK11 uncovers a leptin-mediated sensitivity mechanism to mitochondrial uncouplers for targeted cancer therapy.
Angelopoulou A, Theocharous G, Valakos D, ..., Papaspyropoulos A, Gorgoulis VG
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Distinct Plasma Protein Profiles Distinguish Faster from Slower Disease Progression in HIV-1 and HIV-2 infections
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Using RNAseq to Uncover Transcriptional and Splicing Differences in Host Cells During Rift Valley Fever Virus Infection.
White LA, Havranek KE, Lodmell JS
Methods in molecular biology (Clifton, N.J.) 2824 (-) 373-383 [2024-07-23; online 2024-07-23]
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MpANT regulates meristem development in Marchantia polymorpha.
Liu W, Yang Z, Cai G, ..., Willemsen V, Xu L
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High-Resolution Mass Spectrometry for Human Exposomics: Expanding Chemical Space Coverage.
Lai Y, Koelmel JP, Walker DI, ..., Jones DP, Miller GW
Environ. Sci. Technol. 58 (29) 12784-12822 [2024-07-23; online 2024-07-10]
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Global compositional and functional states of the human gut microbiome in health and disease.
Lee S, Portlock T, Le Chatelier E, ..., Uhlen M, Shoaie S
Genome Res 34 (6) 967-978 [2024-07-23; online 2024-07-23]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
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Protective alleles and precision healthcare in crewed spaceflight.
Rutter LA, MacKay MJ, Cope H, ..., Giacomello S, Mason CE
Nat Commun 15 (1) 6158 [2024-07-22; online 2024-07-22]
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Nematocida displodere mechanosensitive ion channel of small conductance 2 assembles into a unique 6-channel super-structure in vitro.
Berg A, Berntsson RP, Barandun J
PLoS ONE 19 (7) e0301951 [2024-07-22; online 2024-07-22]
Jonas Barandun SciLifeLab Fellow
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Interneuron diversity in the human dorsal striatum.
Garma LD, Harder L, Barba-Reyes JM, ..., Hyman BT, Muñoz-Manchado AB
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Glutamine-addiction in cisplatin resistant cancer cells is mediated by SLC7A11 and can be targeted with asparaginase therapy
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Discovery of Cell-Permeable Allosteric Inhibitors of Liver Pyruvate Kinase: Design and Synthesis of Sulfone-Based Urolithins.
Iqbal S, Islam MZ, Ashraf S, ..., Turkez H, Mardinoglu A
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Adil Mardinoglu SciLifeLab Fellow
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Biallelic pathogenic variants in TRMT1 disrupt tRNA modification and induce a syndromic neurodevelopmental disorder
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Multiscale photocatalytic proximity labeling reveals cell surface neighbors on and between cells.
Lin Z, Schaefer K, Lui I, ..., Sali A, Wells JA
Science (New York, N.Y.) 385 (6706) eadl5763 [2024-07-19; online 2024-07-19]
Andrea Fossati DDLS Fellow
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Hybridization in birds-of-paradise: Widespread ancestral gene flow despite strong sexual selection in a lek-mating system.
Blom MPK, Peona V, Prost S, ..., Suh A, Irestedt M
iScience 27 (7) 110300 [2024-07-19; online 2024-06-19]
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Discovery of a Therapeutic Agent for Glioblastoma Using a Systems Biology-Based Drug Repositioning Approach.
Kaynar A, Ozcan M, Li X, ..., Shoaie S, Mardinoglu A
Int J Mol Sci 25 (14) - [2024-07-18; online 2024-07-18]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
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The Escherichia coli chromosome moves to the replisome.
Gras K, Fange D, Elf J
Nat Commun 15 (1) 6018 [2024-07-17; online 2024-07-17]
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Study on the temporal and spatial distribution of Culex mosquitoes in Hanoi, Vietnam.
Krambrich J, Nguyen-Tien T, Pham-Thanh L, ..., Lindahl JF, Lundkvist Å
Sci Rep 14 (1) 16573 [2024-07-17; online 2024-07-17]
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Electromigrated Gold Nanogap Tunnel Junction Arrays: Fabrication and Electrical Behavior in Liquid and Gaseous Media.
Raja SN, Jain S, Kipen J, ..., Herland A, Niklaus F
ACS Appl Mater Interfaces 16 (28) 37131-37146 [2024-07-17; online 2024-07-02]
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A potential space-making role in cell wall biogenesis for SltB1and DacB revealed by a beta-lactamase induction phenotype in Pseudomonas aeruginosa.
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Waves of transcription drive erythroid differentiation and launch the NRF2-activated antioxidant program
Karppi I, Pessa JC, Rabenius A, ..., Sistonen L, Vihervaara A
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Anniina Vihervaara SciLifeLab Fellow
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Mapping the contribution of the C-linker domain to gating polarity in CNBD channels.
Lin JL, Chang Y, Tewari D, Cowgill J, Chanda B
Biophys. J. 123 (14) 2176-2184 [2024-07-16; online 2024-04-27]
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Insights into mechanisms of MALT1 allostery from NMR and AlphaFold dynamic analyses.
Wallerstein J, Han X, Levkovets M, ..., Agback T, Orekhov V
Commun Biol 7 (1) 868 [2024-07-16; online 2024-07-16]
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Enhancing Molecular Characterization of Dissolved Organic Matter by Integrative Direct Infusion and Liquid Chromatography Nontargeted Workflows.
Patrone J, Vila-Costa M, Dachs J, ..., Gago-Ferrero P, Gil-Solsona R
Environ. Sci. Technol. 58 (28) 12454-12466 [2024-07-16; online 2024-07-03]
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Divergent evolution of male-determining loci on proto-Y chromosomes of the housefly.
Li X, Visser S, Son JH, ..., Bopp D, Beukeboom LW
Nat Commun 15 (1) 5984 [2024-07-16; online 2024-07-16]
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Ancient tree-topologies and gene-flow processes among human lineages in Africa
Breton G, Sjödin P, Zervakis PI, ..., Jakobsson M, Verdu P
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An intracellular hydrophobic nexus critical for hERG1 channel slow deactivation.
Stevens-Sostre WA, Flores-Aldama L, Bustos D, ..., Delemotte L, Robertson GA
Biophys. J. 123 (14) 2024-2037 [2024-07-16; online 2024-01-12]
Lucie Delemotte SciLifeLab Fellow
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TMEM16F scramblase regulates angiogenesis via endothelial intracellular signaling.
Shan KZ, Le T, Liang P, ..., Claesson-Welsh L, Yang H
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Retraction notice to "Combined metabolic activators improve metabolic functions in the animal models of neurodegenerative diseases" [Life Sci. 314 (2023) 121325].
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Life Sci 349 (-) 122712 [2024-07-15; online 2024-05-18]
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Discovery and in vitro Evaluation of Novel Serotonin 5-HT2A Receptor Ligands Identified Through Virtual Screening.
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Maturation of Human Intestinal Epithelial Cell Layers Fortifies the Apical Surface against Salmonella Attack
van Rijn JM, Lopes ACC, Ceylan M, ..., Di Martino ML, Sellin ME
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Advances in development of biomarkers for brain damage and ischemia.
Karimova D, Rostami E, Chubarev VN, ..., Schiöth HB, Rask-Andersen M
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SignalP: The Evolution of a Web Server.
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Microeukaryote community coalescence strengthens community stability and elevates diversity.
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How sex and gender shape functional brain networks.
Matte Bon G, Kraft D, Kaufmann T
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The Left-Right Side-Specific Neuroendocrine Signaling from Injured Brain: An Organizational Principle.
Watanabe H, Kobikov Y, Nosova O, ..., Zhang M, Bakalkin G
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Temporal dynamics of woolly mammoth genome erosion prior to extinction.
Dehasque M, Morales HE, Díez-Del-Molino D, ..., Vartanyan S, Dalén L
Cell 187 (14) 3531-3540.e13 [2024-07-11; online 2024-06-27]
DDLS Fellow Tom van der Valk
PubMed DOI Crossref
Seroepidemiological assessment of the spread of SARS-CoV-2 among 25 and 28 year-old adult women in Finland between March 2020-June 2022.
Gray P, Eriksson T, Skoglund L, ..., Dillner J, Lehtinen M
PLoS ONE 19 (7) e0305285 [2024-07-11; online 2024-07-11]
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Peer Review Report For: Systems Biology in ELIXIR: modelling in the spotlight [version 2; peer review: 2 approved, 1 approved with reservations]
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Molecular Dynamics Simulations in Protein-Protein Docking.
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Cardiomyocyte antisense transcription regulates exon usage in the elastic spring region of Titin to modulate sarcomere function
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Regional Changes in Brain Biomolecular Markers in a Collagen-Induced Arthritis Rat Model.
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Nasal tissue-resident memory CD4 + T cells persist after influenza A virus infection and provide heterosubtypic protection
Mathew NR, Gailleton R, Scharf L, ..., Tang KW, Angeletti D
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Mechanism of phage sensing and restriction by toxin-antitoxin-chaperone systems.
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Cell Host Microbe 32 (7) 1059-1073.e8 [2024-07-10; online 2024-05-30]
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Evolutionary rescue of spherical mreB deletion mutants of the rod-shape bacterium Pseudomonas fluorescens SBW25
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Characterization of a lipid-based jumbo phage compartment as a hub for early phage infection.
Mozumdar D, Fossati A, Stevenson E, ..., Swaney DL, Bondy-Denomy J
Cell Host Microbe 32 (7) 1050-1058.e7 [2024-07-10; online 2024-06-12]
Andrea Fossati DDLS Fellow
DOI Crossref
Cerebrospinal fluid levels of NfM in relation to NfL and pNfH as prognostic markers in amyotrophic lateral sclerosis
Olofsson J, Bergström S, Mravinacová S, ..., Nilsson P, Månberg A
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Associations between Microglia and Astrocytic Proteins and Tau Biomarkers across the Continuum of Alzheimer's Disease.
Doroszkiewicz J, Kulczyńska-Przybik A, Dulewicz M, ..., Blennow K, Mroczko B
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Advancing drug discovery through assay development: a survey of tool compounds within the human solute carrier superfamily.
Digles D, Ingles-Prieto A, Dvorak V, ..., Wiedmer T, Superti-Furga G
Front. Pharmacol. 15 (-) 1401599 [2024-07-09; online 2024-07-09]
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Simulating the Skin Permeation Process of Ionizable Molecules.
Lundborg M, Wennberg C, Lindahl E, Norlén L
J Chem Inf Model 64 (13) 5295-5302 [2024-07-08; online 2024-06-25]
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Genome-scale metabolic network of human carotid plaque reveals the pivotal role of glutamine/glutamate metabolism in macrophage modulating plaque inflammation and vulnerability.
Jin H, Zhang C, Nagenborg J, ..., Mardinoglu A, Biessen EAL
Cardiovasc Diabetol 23 (1) 240 [2024-07-08; online 2024-07-08]
Adil Mardinoglu SciLifeLab Fellow
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Broadcasters, receivers, functional groups of metabolites, and the link to heart failure by revealing metabolomic network connectivity.
Yazdani A, Mendez-Giraldez R, Yazdani A, ..., Larson MG, Elsea SH
Metabolomics 20 (4) 71 [2024-07-07; online 2024-07-07]
Clemens Wittenbecher DDLS Fellow
DOI Crossref
SOX21 Suppresses Glioblastoma Growth by Repressing AP-1 Activity
Rrapaj E, Yuan J, Kurtsdotter I, ..., Bergsland M, Muhr J
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Cellular and molecular events organizing the assembly of tertiary lymphoid structures in glioblastoma
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ADAR-Mediated A>I(G) RNA Editing in the Genotoxic Drug Response of Breast Cancer.
Bernal YA, Durán E, Solar I, Sagredo EA, Armisén R
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Nucleotide binding to the ATP-cone in anaerobic ribonucleotide reductases allosterically regulates activity by modulating substrate binding.
Bimai O, Banerjee I, Rozman Grinberg I, ..., Sjöberg BM, Logan DT
Elife 12 (-) - [2024-07-05; online 2024-07-05]
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Nucleotide binding to the ATP-cone in anaerobic ribonucleotide reductases allosterically regulates activity by modulating substrate binding
Bimai O, Banerjee I, Rozman Grinberg I, ..., Sjöberg BM, Logan DT
Elife 12 (-) - [2024-07-05; online 2024-07-05]
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A generalizable data-driven model of atrophy heterogeneity and progression in memory clinic settings.
Baumeister H, Vogel JW, Insel PS, ..., Hansson O, Berron D
Brain 147 (7) 2400-2413 [2024-07-05; online 2024-04-24]
DDLS Fellow Jacob W Vogel
PubMed DOI Crossref
Rapid genome sequencing for critically ill infants: an inaugural pilot study from Turkey.
Guner Yilmaz B, Akgun-Dogan O, Ozdemir O, ..., Ozbek U, Alanay Y
Front Pediatr 12 (-) 1412880 [2024-07-04; online 2024-07-04]
Adil Mardinoglu SciLifeLab Fellow
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Immunoglobulin A Nephropathy: Population Characteristics, Humanistic Burden, and Kidney Outcomes According to Albuminuria
Csomor P, Szklarzewicz J, Faucon AL
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A single-cell transcriptomic study of heterogeneity in human embryonic tanycytes.
Bai Y, Chen Q, Li Y
Sci Rep 14 (1) 15384 [2024-07-04; online 2024-07-04]
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P-159 Single-cell high-throughput methylation and transcriptomic analysis indicates variations in sensitivity to Folate-mediated one-carbon metabolism in mouse preimplantation embryos
Reyes Palomares A, Vincelle-Nieto A, Tavares Barroso M, ..., Reyes-Palomares A, Rodriguez-Wallberg K
Hum. Reprod. 39 (Supplement_1) - [2024-07-03; online 2024-07-03]
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Mammalian cell display with automated oligo design and library assembly allows for rapid residue level conformational epitope mapping.
Thalén NB, Karlander M, Lundqvist M, ..., Ohlin M, Rockberg J
Commun Biol 7 (1) 805 [2024-07-03; online 2024-07-03]
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Limited Parallelism in Genetic Adaptation to Brackish Water Bodies in European Sprat and Atlantic Herring.
Pettersson ME, Quintela M, Besnier F, ..., Glover KA, Andersson L
Genome Biol Evol 16 (7) - [2024-07-03; online 2024-06-26]
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Historic dog Furs Unravel the Origin and Artificial Selection of Modern Nordic Lapphund and Elkhound dog Breeds.
Wang SZ, Yan Y, Widlund M, ..., Savolainen P, Wang GD
Mol. Biol. Evol. 41 (7) - [2024-07-03; online 2024-06-06]
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High Caveolin-1 mRNA expression in triple-negative breast cancer is associated with an aggressive tumor microenvironment, chemoresistance, and poor clinical outcome.
Godina C, Khazaei S, Belting M, ..., Bosch A, Jernström H
PLoS ONE 19 (7) e0305222 [2024-07-03; online 2024-07-03]
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Flotillin-mediated stabilization of unfolded proteins in bacterial membrane microdomains.
Ukleja M, Kricks L, Torrens G, ..., Cava F, Lopez D
Nat Commun 15 (1) 5583 [2024-07-03; online 2024-07-03]
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Investigations of microbiota composition and neuroactive pathways in association with symptoms of stress and depression in a cohort of healthy women.
Bashir Z, Hugerth LW, Krog MC, ..., Fransson E, Nielsen HS
Front. Cell. Infect. Microbiol. 14 (-) 1324794 [2024-07-02; online 2024-07-02]
DDLS Fellow Luisa Hugerth
PubMed DOI Crossref
CRISPR-Cas9 Knockout Screens Identify DNA Damage Response Pathways and BTK as Essential for Cisplatin Response in Diffuse Large B-Cell Lymphoma.
Issa II, Due H, Brøndum RF, ..., Schmierer B, Dybkær K
Cancers (Basel) 16 (13) - [2024-07-02; online 2024-07-02]
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Vaginal Microbiota Transplantation (VMT) for treatment of vaginal dysbiosis without the use of antibiotics – A Double-Blinded Randomized Controlled Trial in healthy women with vaginal dysbiosis
Wrønding T, Vomstein K, DeLong K, ..., Ensign LM, Nielsen HS
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DDLS Fellow Luisa Hugerth
PubMed DOI Crossref
Unravelling reference bias in ancient DNA datasets.
Dolenz S, van der Valk T, Jin C, ..., Dalén L, Heintzman PD
Bioinformatics 40 (7) - [2024-07-01; online 2024-07-04]
DDLS Fellow Tom van der Valk
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The role of prepulse inhibition in predicting new-onset postpartum depression
Eriksson A, Björvang RD, Ancker E, ..., Fransson E, Skalkidou A
Nat. Mental Health 2 (8) 901-908 [2024-07-01; online 2024-07-01]
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MDverse: Shedding Light on the Dark Matter of Molecular Dynamics Simulations
Tiemann JKS, Szczuka M, Bouarroudj L, ..., Chavent M, Poulain P
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Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
High-bandwidth low-current measurement system for automated and scalable probing of tunnel junctions in liquids.
Raja SN, Jain S, Kipen J, ..., Herland A, Niklaus F
Rev Sci Instrum 95 (7) - [2024-07-01; online 2024-07-22]
PubMed DOI Crossref
Deletion of CD44 promotes adipogenesis by regulating PPARγ and cell cycle-related pathways.
Weng X, Jiang H, Walker DJ, ..., Wang J, Kang L
J Endocrinol 262 (1) - [2024-07-01; online 2024-05-20]
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Carboxyl-group compounds activate voltage-gated potassium channels via a distinct mechanism.
Rönnelid O, Elinder F
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Cancer Core Europe: Leveraging Institutional Synergies to Advance Oncology Research and Care Globally.
Carmona J, Chavarria E, Donoghue K, ..., Zwart W, Tabernero J
Cancer Discov 14 (7) 1147-1153 [2024-07-01; online 2024-06-13]
PubMed DOI Crossref
CCG-1423-derived compounds reduce global RNA synthesis and inhibit transcriptional responses.
Prajapati B, Sokolova M, Sidorenko E, ..., Vihervaara A, Vartiainen MK
J. Cell. Sci. 137 (13) - [2024-07-01; online 2024-07-15]
Anniina Vihervaara SciLifeLab Fellow
PubMed DOI Crossref
BirthSeq, a new method to isolate and analyze dated cells in different vertebrates.
Rueda-Alaña E, Grillo M, Vázquez E, ..., Nilsson M, García-Moreno F
Development 151 (13) - [2024-07-01; online 2024-07-10]
DOI Crossref
Author response: MDverse: Shedding Light on the Dark Matter of Molecular Dynamics Simulations
Tiemann JKS, Szczuka M, Bouarroudj L, ..., Chavent M, Poulain P
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Lucie Delemotte SciLifeLab Fellow
PubMed DOI Crossref
Special issue: TGF-β and epithelial-mesenchymal transition in cancer.
Ten Dijke P, Miyazono K, Heldin CH, Moustakas A
Semin. Cancer Biol. 102-103 (-) 1-3 [2024-07-00; online 2024-06-27]
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Spatial multimodal analysis of transcriptomes and metabolomes in tissues.
Vicari M, Mirzazadeh R, Nilsson A, ..., Andrén PE, Lundeberg J
Nat. Biotechnol. 42 (7) 1046-1050 [2024-07-00; online 2023-09-04]
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Smad7 palmitoylation by the S-acyltransferase zDHHC17 enhances its inhibitory effect on TGF-β/Smad signaling.
Voytyuk O, Ohata Y, Moustakas A, Ten Dijke P, Heldin CH
J Biol Chem 300 (7) 107462 [2024-07-00; online 2024-06-12]
PubMed DOI Crossref
SGLT2 inhibitors in clinical practice.
Rydén L, Norhammar A
The Lancet Diabetes & Endocrinology 12 (7) 434-435 [2024-07-00; online 2024-05-17]
PubMed DOI Crossref
Precision Diagnostics in Myeloid Malignancies: Development and Validation of a National Capture-Based Gene Panel.
Orsmark-Pietras C, Lyander A, Ladenvall C, ..., Fioretos T, SciLifeLab Clinical Genomics Platform and Genomic Medicine Sweden
Genes Chromosomes Cancer 63 (7) e23257 [2024-07-00; online 2024-07-20]
PubMed DOI Crossref
On-Chip Neural Induction Boosts Neural Stem Cell Commitment: Toward a Pipeline for iPSC-Based Therapies.
Jain S, Voulgaris D, Thongkorn S, ..., Falk A, Herland A
Adv Sci (Weinh) 11 (25) e2401859 [2024-07-00; online 2024-04-24]
PubMed DOI Crossref
Novel drug targets and molecular mechanisms for sarcopenia based on systems biology.
Ceyhan AB, Ozcan M, Kim W, ..., Zhang C, Mardinoglu A
Biomed. Pharmacother. 176 (-) 116920 [2024-07-00; online 2024-06-13]
PubMed DOI Crossref
Lipid imaging of Alzheimer's disease pathology.
Hanrieder J
J. Neurochem. 168 (7) 1175-1178 [2024-07-00; online 2024-02-19]
PubMed DOI Crossref
Integrative analysis of ultra-deep RNA-seq reveals alternative promoter usage as a mechanism of activating oncogenic programmes during prostate cancer progression.
Zhang M, Sjöström M, Cui X, ..., Feng FY, Quigley DA
Nat. Cell Biol. 26 (7) 1176-1186 [2024-07-00; online 2024-06-13]
Arian Lundberg DDLS Fellow
PubMed DOI Crossref
Improved protein complex prediction with AlphaFold-multimer by denoising the MSA profile.
Bryant P, Noé F
PLoS Comput Biol 20 (7) e1012253 [2024-07-00; online 2024-07-25]
DDLS Fellow Patrick Bryant
DOI Crossref
Identification of Gene‐Therapy Responsive Blood Biomarkers in mdx Mouse Model
Johansson C, Boehler JF, Brown KJ, ..., Spitali P, Al‐Khalili Szigyarto C
JCSM Communications 7 (2) 187-198 [2024-07-00; online 2024-12-17]
PubMed DOI Crossref
GABA-mediated inhibition of human CD4+ T cell functions is enhanced by insulin but impaired by high glucose levels.
Jin Z, Hammoud H, Bhandage AK, ..., Kamali-Moghaddam M, Birnir B
EBioMedicine 105 (-) 105217 [2024-07-00; online 2024-06-28]
Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
Exploring BPA alternatives - Environmental levels and toxicity review.
Adamovsky O, Groh KJ, Białk-Bielińska A, ..., Blaha L, Kyriakopoulou K
Environ Int 189 (-) 108728 [2024-07-00; online 2024-05-23]
Lars Behrendt SciLifeLab Fellow
DOI Crossref
Evaluation of activated sludge settling characteristics from microscopy images with deep convolutional neural networks and transfer learning
Borzooei S, Scabini L, Miranda G, ..., Nopens I, Torfs E
Journal of Water Process Engineering 64 (-) 105692 [2024-07-00; online 2024-07-00]
Gisele Miranda SciLifeLab Fellow
PubMed DOI Crossref
Eosinophilic esophagitis and risk of incident major adverse cardiovascular events: a nationwide matched cohort study.
Forss A, Uchida AM, Roelstraete B, ..., Sundström J, Ludvigsson JF
Esophagus 21 (3) 365-373 [2024-07-00; online 2024-05-29]
PubMed DOI Crossref
Enhancing Neuronal Cell Uptake of Therapeutic Nucleic Acids with Tetrahedral DNA Nanostructures.
Martins ASG, Reis SD, Benson E, ..., Pêgo AP, Moreno PMD
Small 20 (29) e2309140 [2024-07-00; online 2024-02-11]
Erik Benson SciLifeLab Fellow
DOI Crossref
Enhanced Cellular Uptake through Nanotopography‐Induced Macropinocytosis (Adv. Funct. Mater. 28/2024)
Aramesh M, Yu D, Essand M, Persson C
Adv. Funct. Mater. 34 (28) - [2024-07-00; online 2024-07-10]
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Enhanced Cellular Uptake through Nanotopography‐Induced Macropinocytosis
Aramesh M, Yu D, Essand M, Persson C
Adv. Funct. Mater. 34 (28) - [2024-07-00; online 2024-03-13]
PubMed DOI Crossref
Engineering of Saccharomyces cerevisiae for enhanced metabolic robustness and L-lactic acid production from lignocellulosic biomass.
Choi B, Tafur Rangel A, Kerkhoven EJ, Nygård Y
Metab. Eng. 84 (-) 23-33 [2024-07-00; online 2024-05-23]
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Effects and avoidance of photoconversion-induced artifacts in confocal and STED microscopy.
Dasgupta A, Koerfer A, Kokot B, ..., Eggeling C, Carravilla P
Nat. Methods 21 (7) 1171-1174 [2024-07-00; online 2024-06-04]
PubMed DOI Crossref
Dietary fatty acids and incident hip fractures in cohorts of women and men. A relative validation and follow-up study.
Warensjö Lemming E, Byberg L, Höijer J, ..., Wolk A, Michaëlsson K
J Nutr Health Aging 28 (7) 100247 [2024-07-00; online 2024-04-25]
PubMed DOI Crossref
Detection and quantification of Na,K-ATPase dimers in the plasma membrane of living cells by FRET-FCS.
Nordahl L, Akkuratov EE, Heimgärtner J, ..., Wennmalm S, Brismar H
Biochim Biophys Acta Gen Subj 1868 (7) 130619 [2024-07-00; online 2024-04-20]
SciLifeLab Fellow Simon Elsässer
PubMed DOI Crossref
Deconwolf enables high-performance deconvolution of widefield fluorescence microscopy images.
Wernersson E, Gelali E, Girelli G, ..., Crosetto N, Bienko M
Nat. Methods 21 (7) 1245-1256 [2024-07-00; online 2024-06-06]
Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
Corrigendum to "Discovery of therapeutic agents targeting PKLR for NAFLD using drug repositioning" [eBioMedicine, 2022;83:104214].
Zhang C, Shi M, Kim W, ..., Boren J, Mardinoglu A
EBioMedicine 105 (-) 105224 [2024-07-00; online 2024-06-28]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
PubMed DOI Crossref
Comparison of Xrn1 and Rat1 5' → 3' exoribonucleases in budding yeast supports the specific role of Xrn1 in cotranslational mRNA decay.
Pérez-Ortín JE, Jordán-Pla A, Zhang Y, ..., Pelechano V, García-Martínez J
Yeast 41 (7) 458-472 [2024-07-00; online 2024-06-14]
SciLifeLab Fellow
PubMed DOI Crossref
Cleanroom-Free Direct Laser Micropatterning of Polymers for Organic Electrochemical Transistors in Logic Circuits and Glucose Biosensors.
Enrico A, Buchmann S, De Ferrari F, ..., Herland A, Zeglio E
Adv Sci (Weinh) 11 (27) e2307042 [2024-07-00; online 2024-01-15]
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Cactus: A user-friendly and reproducible ATAC-Seq and mRNA-Seq analysis pipeline for data preprocessing, differential analysis, and enrichment analysis.
Salignon J, Millan-Ariño L, Garcia MU, Riedel CG
Genomics 116 (4) 110858 [2024-07-00; online 2024-05-11]
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Being Breastfed in Infancy and Risk of Colorectal Cancer and Precursor Lesions.
Yuan C, Wang QL, Kim H, ..., Giovannucci EL, Ng K
Clin Gastroenterol Hepatol 22 (7) 1508-1517.e11 [2024-07-00; online 2023-09-06]
DDLS Fellow Qiaoli Wang
PubMed DOI Crossref
A community effort to track commercial single-cell and spatial 'omic technologies and business trends.
De Jonghe J, Opzoomer JW, Vilas-Zornoza A, ..., Cribbs AP, Taylor-King JP
Nat. Biotechnol. 42 (7) 1017-1023 [2024-07-00; online 2024-07-18]
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The quantification of zebrafish ocular-associated proteins provides hints for sex-biased visual impairments and perception.
Niksirat H, Siino V, Steinbach C, Levander F
Heliyon 10 (12) e33057 [2024-06-30; online 2024-06-13]
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Membrane topography and the overestimation of protein clustering in single molecule localisation microscopy - identification and correction.
Adler J, Bernhem K, Parmryd I
Commun Biol 7 (1) 791 [2024-06-29; online 2024-06-29]
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Population History and Admixture of the Fulani People from the Sahel
Fortes-Lima CA, Diallo MY, Janoušek V, Černý V, Schlebusch CM
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CPSign: conformal prediction for cheminformatics modeling.
Arvidsson McShane S, Norinder U, Alvarsson J, ..., Carlsson L, Spjuth O
J Cheminform 16 (1) 75 [2024-06-28; online 2024-06-28]
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A combination of long- and short-read genomics reveals frequent p-arm breakpoints within chromosome 21 complex genomic rearrangements.
Schuy J, Sæther KB, Lisfeld J, ..., Eisfeldt J, Lindstrand A
Genetics in Medicine Open 2 (-) 101863 [2024-06-28; online 2024-06-28]
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Predicting type 2 diabetes via machine learning integration of multiple omics from human pancreatic islets.
Rönn T, Perfilyev A, Oskolkov N, Ling C
Sci Rep 14 (1) 14637 [2024-06-25; online 2024-06-25]
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Implementing AI in Advanced Recycling of Perovskite Solar Cells
Sprague CI, de la Asunción-Nadal V, García-Fernández A
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PubMed DOI Crossref
Elasto-inertial focusing and particle migration in high aspect ratio microchannels for high-throughput separation.
Tanriverdi S, Cruz J, Habibi S, ..., Tammisola O, Russom A
Microsyst. Nanoeng. 10 (-) 87 [2024-06-25; online 2024-06-25]
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Decrypting lysine deacetylase inhibitor action and protein modifications by dose-resolved proteomics.
Chang YC, Gnann C, Steimbach RR, ..., Miller AK, Kuster B
Cell Reports 43 (6) 114272 [2024-06-25; online 2024-05-24]
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The future of data integration – Shaping ELIXIR’s interoperability platform with <i>real-world</i> use cases
Nyberg Åkerström W, Hermoso Pulido A, Welter D, ..., Kheng Teh W, Gundersen S
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Design of linear and cyclic peptide binders of different lengths from protein sequence information
Li Q, Vlachos EN, Bryant P
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DDLS Fellow Patrick Bryant
PubMed DOI Crossref
Quantification and Profiling of Early and Late Differentiation Stage T Cells in Mantle Cell Lymphoma Reveals Immunotherapeutic Targets in Subsets of Patients.
Lokhande L, Nilsson D, de Matos Rodrigues J, ..., Jerkeman M, Ek S
Cancers (Basel) 16 (13) - [2024-06-21; online 2024-06-21]
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Mass Spectrometry Proteomics Characterization of Plasma Biomarkers for Colorectal Cancer Associated With Inflammation.
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Turnbull K, Paternoga H, von der Weth E, ..., Wilson DN, Hauryliuk V
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Bryant P, Kelkar A, Guljas A, Clementi C, Noé F
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DDLS Fellow Patrick Bryant
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Sci Rep 14 (1) 12177 [2024-05-28; online 2024-05-28]
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Bacillamide D produced by Bacillus cereus from the mouse intestinal bacterial collection (miBC) is a potent cytotoxin in vitro.
Hohmann M, Brunner V, Johannes W, ..., Janßen KP, Gulder TAM
Commun Biol 7 (1) 655 [2024-05-28; online 2024-05-28]
DDLS Fellow Laura Carroll
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An Automated Versatile Diagnostic Workflow for Infectious Disease Detection in Low-Resource Settings.
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2-Aryladenine Derivatives as a Potent Scaffold for Adenosine Receptor Antagonists: The 6-Morpholino Derivatives.
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Molecules 29 (11) - [2024-05-28; online 2024-05-28]
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Polycyclic Aromatic Compounds 44 (5) 3061-3078 [2024-05-27; online 2023-07-16]
Adil Mardinoglu SciLifeLab Fellow
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Self-Supervised Learning for Genetically Relevant Domain Identification in Morphological Images
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Cheng L, Correia MSP, Higdon SM, ..., Globisch D, Du J
Gut Microbes 16 (1) 2356275 [2024-05-26; online 2024-05-26]
Daniel Globisch SciLifeLab Fellow
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Structure of the II2-III2-IV2 mitochondrial supercomplex from the parasite Perkinsus marinus
Wú F, Mühleip A, Gruhl T, ..., Maréchal A, Amunts A
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Alexey Amunts SciLifeLab Fellow
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Mitotic MTH1 inhibitor TH1579 induces PD-L1 expression and inflammatory response through the cGAS-STING pathway.
Shen J, Guillén Mancina E, Chen S, ..., Sanjiv K, Helleday T
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Deep Texture Feature Aggregation on Leaf Microscopy Images for Brazilian Plant Species Recognition
Scabini L, Zielinski K, Fares R, ..., Ribas L, Bruno O
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Gisele Miranda SciLifeLab Fellow
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Illuminating the function of the orphan transporter, SLC22A10, in humans and other primates.
Yee SW, Ferrández-Peral L, Alentorn-Moron P, ..., Marquès-Bonet T, Giacomini KM
Nat Commun 15 (1) 4380 [2024-05-23; online 2024-05-23]
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FLT3L governs the development of partially overlapping hematopoietic lineages in humans and mice.
Momenilandi M, Lévy R, Sobrino S, ..., Casanova JL, Béziat V
Cell 187 (11) 2817-2837.e31 [2024-05-23; online 2024-05-03]
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Effectiveness and Cost-effectiveness of Artificial Intelligence-assisted Pathology for Prostate Cancer Diagnosis in Sweden: A Microsimulation Study.
Du X, Hao S, Olsson H, ..., Eklund M, Clements M
Eur Urol Oncol - (-) - [2024-05-23; online 2024-05-23]
DDLS Fellow Kimmo Kartasalo
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Allosteric Cholesterol Site in Glycine Receptors Characterized through Molecular Simulations.
Jalalypour F, Howard RJ, Lindahl E
J Phys Chem B 128 (20) 4996-5007 [2024-05-23; online 2024-05-15]
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#983 Identification of gut microbiome signatures associated with albuminuria in diabetes mellitus
Lin YT, Sayols-Baixeras S, Dekkers K, ..., Fall T, Ärnlöv J
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Elevated levels of IL-12/IL-23p40 in Nova Scotia Duck Tolling Retrievers with autoimmune disease and lymphoma.
Nilsson M, Kozyrev SV, Saellström S, ..., Hansson-Hamlin H, Rönnberg H
Sci Rep 14 (1) 11624 [2024-05-21; online 2024-05-21]
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Diagnosis of Cancer After Recent Weight Loss-Reply.
Wang QL, Yuan C, Wolpin BM
JAMA 331 (19) 1678-1679 [2024-05-21; online 2024-04-24]
DDLS Fellow Qiaoli Wang
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Mitoribosome structure with cofactors and modifications reveals mechanism of ligand binding and interactions with L1 stalk.
Singh V, Itoh Y, Del'Olio S, ..., Taoka M, Amunts A
Nat Commun 15 (1) 4272 [2024-05-20; online 2024-05-20]
Alexey Amunts SciLifeLab Fellow
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MDM2 amplification in rod-shaped chromosomes provides clues to early stages of circularized gene amplification in liposarcoma.
Sydow S, Piccinelli P, Mitra S, ..., Spierings D, Mertens F
Commun Biol 7 (1) 606 [2024-05-20; online 2024-05-20]
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Non-invasive PET imaging of liver fibrogenesis using a RESCA-conjugated Affibody molecule.
Wegrzyniak O, Lechi F, Mitran B, ..., Zhang B, Eriksson O
iScience 27 (5) 109688 [2024-05-17; online 2024-04-10]
Olof Eriksson SciLifeLab Fellow
DOI Crossref
Gaps between Open Science activities and actual recognition systems: Insights from an international survey
Grattarola F, Shmagun H, Erdmann C, ..., Kim J, Mabile L
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An atlas of protein-protein associations of human tissues prioritizes candidate disease genes
Laman Trip DS, van Oostrum M, Memon D, ..., Wollscheid B, Beltrao P
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Andrea Fossati DDLS Fellow
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The full spectrum of SLC22 OCT1 mutations illuminates the bridge between drug transporter biophysics and pharmacogenomics.
Yee SW, Macdonald CB, Mitrovic D, ..., Giacomini KM, Coyote-Maestas W
Mol. Cell 84 (10) 1932-1947.e10 [2024-05-16; online 2024-05-03]
Lucie Delemotte SciLifeLab Fellow
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Streptolysin O Accelerates the Conversion of Plasminogen to Plasmin
Tang D, Khakzad H, Hjortswang E, ..., Happonen L, Malmström J
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Microfluidic Cartridge for Bead-Based Affinity Assays.
Pinto IF, Chotteau V, Russom A
Methods in molecular biology (Clifton, N.J.) 2804 (-) 127-138 [2024-05-16; online 2024-05-16]
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Compositional and functional differences of the vaginal microbiota of women with and without cervical dysplasia.
Norenhag J, Edfeldt G, Stålberg K, ..., Schuppe-Koistinen I, Olovsson M
Sci Rep 14 (1) 11183 [2024-05-16; online 2024-05-16]
DDLS Fellow Luisa Hugerth
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Novel findings in a Swedish primary familial brain calcification cohort.
Sennfält S, Gustavsson P, Malmgren H, ..., Svenningsson P, Paucar M
J. Neurol. Sci. 460 (-) 123020 [2024-05-15; online 2024-04-18]
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Modeling brain sex in the limbic system as phenotype for female-prevalent mental disorders.
Matte Bon G, Kraft D, Comasco E, Derntl B, Kaufmann T
Biol Sex Differ 15 (1) 42 [2024-05-15; online 2024-05-15]
Erika Comasco SciLifeLab Fellow
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Hypersensitive blood vessels in Clarkson disease.
Nwadozi E, Claesson-Welsh L
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Clear effects on root system architecture of winter wheat cultivars (Triticum aestivum L.) from cultivation environment and practices.
Cope JE, Berckx F, Lundmark J, ..., Karlsson I, Weih M
Sci Rep 14 (1) 11099 [2024-05-15; online 2024-05-15]
DOI Crossref
Spatial Coherence in DNA Barcode Networks
Bonet DF, Blumenthal JI, Lang S, Dahlberg SK, Hoffecker IT
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Empowering bioinformatics communities with Nextflow and nf-core
Langer BE, Amaral A, Baudement MO, ..., Espinosa-Carrasco J, Notredame C
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Nucleobase catalysts for the enzymatic activation of 8-oxoguanine DNA glycosylase 1
Hank EC, D'Arcy-Evans N, Scaletti ER, ..., Helleday T, Michel M
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Iron oxide nanoparticles for treatment and diagnosis of chronic inflammatory diseases: A systematic review.
Ansari SR, Mahajan J, Teleki A
Wiley Interdiscip Rev Nanomed Nanobiotechnol 16 (3) e1963 [2024-05-10; online 2024-05-10]
Alexandra Teleki SciLifeLab Fellow
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TPP1 is associated with risk of advanced precursors and cervical cancer survival.
Wang QL, Gong C, Meng XY, ..., Wu Q, Zhou Y
PLoS ONE 19 (5) e0298118 [2024-05-09; online 2024-05-09]
DDLS Fellow Qiaoli Wang
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Chromatin damage generated by DNA intercalators leads to degradation of RNA Polymerase II.
Espinoza JA, Kanellis DC, Saproo S, ..., Bartek J, Lindström MS
Nucleic Acids Res. 52 (8) 4151-4166 [2024-05-08; online 2024-02-10]
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Longitudinal molecular profiling elucidates immunometabolism dynamics in breast cancer.
Wang K, Zerdes I, Johansson HJ, ..., Matikas A, Foukakis T
Nat Commun 15 (1) 3837 [2024-05-07; online 2024-05-07]
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A Decade in a Systematic Review: The Evolution and Impact of Cell Painting.
Seal S, Trapotsi MA, Spjuth O, ..., Bender A, Carpenter AE
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Induced Formation of Plasma Membrane Protrusions with Porous Materials as Instructive Surfaces.
Aramesh M, Persson C
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High Resolution Crystal Structure of the Pyruvate Kinase Tetramer in Complex with the Allosteric Activator Mitapivat/AG-348
Han X, Sandalova T, Zhang C, ..., Achour A, Sun R
Crystals 14 (5) 441 [2024-05-05; online 2024-05-05]
Adil Mardinoglu SciLifeLab Fellow
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GROMACS on AMD GPU-Based HPC Platforms: Using SYCL for Performance and Portability
Alekseenko A, Páll S, Lindahl E
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Adaptive sampling-based structural prediction reveals opening of a GABA receptor through the αβ interface
Haloi N, Howard RJ, Lindahl E
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MDverse: Shedding Light on the Dark Matter of Molecular Dynamics Simulations.
Tiemann JKS, Szczuka M, Bouarroudj L, ..., Chavent M, Poulain P
bioRxiv - (-) - [2024-05-03; online 2024-05-03]
Lucie Delemotte SciLifeLab Fellow
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Genetic Causes and Genomic Consequences of Breakdown of Distyly in Linum trigynum.
Gutiérrez-Valencia J, Zervakis PI, Postel Z, ..., Arroyo J, Slotte T
Mol. Biol. Evol. 41 (5) - [2024-05-03; online 2024-05-06]
SciLifeLab Fellow Tanja Slotte
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Differential expression of plasma proteins in pregnant women exposed to Plasmodium falciparum malaria
Kanoi BN, Waweru H, Kobia FM, ..., Gitaka J, Kamali-Moghaddam M
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Determinants of the Divergent Salmonella and Shigella Epithelial Colonization Strategies Resolved in Human Enteroids and Colonoids
Geiser P, Martino MLD, Lopes ACC, ..., Eriksson J, Sellin ME
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Mikael Sellin SciLifeLab Fellow
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Comparative genomics of Ascetosporea gives new insight into the evolutionary basis for animal parasitism in Rhizaria.
Hiltunen Thorén M, Onuț-Brännström I, Alfjorden A, ..., Bass D, Burki F
BMC Biol. 22 (1) 103 [2024-05-03; online 2024-05-03]
Fabien Burki SciLifeLab Fellow
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Artificial intelligence for omics data analysis
Ahmed Z, Wan S, Zhang F, Zhong W
BMC Methods 1 (1) - [2024-05-03; online 2024-05-03]
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Ancestral terpene cyclases: From fundamental science to applications in biosynthesis.
Syrén PO
Meth. Enzymol. 699 (-) 311-341 [2024-05-03; online 2024-05-03]
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Stereoselective Synthesis of the Gal-α-(1→3)-Gal-β-(1→3)-GlcNAc Trisaccharide: a new Ligand for DCAR and Mincle C-Type Lectin Receptors.
Tricomi J, Aoun M, Xu B, Holmdahl R, Richichi B
Chembiochem 25 (9) e202400026 [2024-05-02; online 2024-04-08]
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Spatial transcriptomics Visium data for mouse bleomycin model of lung fibrosis
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Removing scanner effects with a multivariate latent approach: A RELIEF for the ABCD imaging data?
Kraft D, Bon GM, Breton É, Seidel P, Kaufmann T
Imaging Neurosci (Camb) 2 (-) - [2024-05-02; online 2024-05-02]
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Experimental Evaluation of a Direct Fitness Effect of the De Novo Evolved Mouse Gene Pldi.
Linnenbrink M, Breton G, Misra P, ..., Dutheil JY, Tautz D
Genome Biol Evol 16 (5) - [2024-05-02; online 2024-05-14]
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Evolutionary convergence of sensory circuits in the pallium of amniotes
Rueda-Alaña E, Senovilla-Ganzo R, Grillo M, ..., De Pitta M, García-Moreno F
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CopyVAE: a variational autoencoder-based approach for copy number variation inference using single-cell transcriptomics.
Kurt S, Chen M, Toosi H, ..., Hartman J, Lagergren J
Bioinformatics 40 (5) - [2024-05-02; online 2024-04-28]
Camilla Engblom SciLifeLab Fellow
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Abstract PO5-13-02: BRCA mutational profiles of endocrine-resistant breast cancer
Karlsson E, Schagerholm C, Robertson S, ..., Sifakis E, Hartman J
Cancer Res. 84 (9_Supplement) PO5-13-02-PO5-13-02 [2024-05-02; online 2024-05-02]
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Abstract PO3-25-07: Characterization of tertiary lymphoid structures and its association with response to immune checkpoint inhibitors in triple negative breast cancer using spatial transcriptomics
Wang X, Venet D, Lifrange F, ..., Rothé F, Sotiriou C
Cancer Res. 84 (9_Supplement) PO3-25-07-PO3-25-07 [2024-05-02; online 2024-05-02]
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Transcriptomic analysis of cellular hypoxia response pathways in human endothelial cells
Lindqvist E, Bergström A, Johansson L, Andersson S
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Multiple cis-regulatory elements control prox1a expression in distinct lymphatic vascular beds.
Panara V, Yu H, Peng D, ..., Hogan BM, Koltowska K
Development 151 (9) - [2024-05-01; online 2024-05-09]
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Male-transmitted transgenerational effects of the herbicide linuron on DNA methylation profiles in Xenopus tropicalis brain and testis.
Roza M, Eriksson ANM, Svanholm S, Berg C, Karlsson O
Sci. Total Environ. 923 (-) 170949 [2024-05-01; online 2024-02-15]
Oskar Karlsson SciLifeLab Fellow
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Dynamics of the blood plasma proteome during hyperacute HIV-1 infection
Nazziwa J, Freyhult E, Hong MG, ..., Hassan AS, Esbjörnsson J
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Cerebrospinal fluid reference proteins increase accuracy and interpretability of biomarkers for brain diseases.
Karlsson L, Vogel J, Arvidsson I, ..., Mattsson-Carlgren N, Hansson O
Nat Commun 15 (1) 3676 [2024-05-01; online 2024-05-01]
DDLS Fellow Jacob W Vogel
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Acquired Multidrug Resistance in AML Is Caused by Low Apoptotic Priming in Relapsed Myeloblasts.
Olesinski EA, Bhatia KS, Wang C, ..., Letai A, Bhatt S
Blood Cancer Discov 5 (3) 180-201 [2024-05-01; online 2024-03-05]
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White matter volume and treatment with selective progesterone receptor modulator in patients with premenstrual dysphoric disorder.
Kaltsouni E, Wikström J, Lanzenberger R, Sundström-Poromaa I, Comasco E
Psychoneuroendocrinology 163 (-) 106977 [2024-05-00; online 2024-01-22]
Erika Comasco SciLifeLab Fellow
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The decanoate esters of nandrolone, testosterone, and trenbolone induce steroid specific memory impairment and somatic effects in the male rat.
Zelleroth S, Stam F, Nylander E, ..., Grönbladh A, Hallberg M
Horm Behav 161 (-) 105501 [2024-05-00; online 2024-02-17]
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The anti-leprosy drug clofazimine reduces polyQ toxicity through activation of PPARγ.
Li X, Hernandez I, Koyuncu S, ..., Vilchez D, Fernandez-Capetillo O
EBioMedicine 103 (-) 105124 [2024-05-00; online 2024-05-02]
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Super-sectioning with multi-sheet reversible saturable optical fluorescence transitions (RESOLFT) microscopy.
Bodén A, Ollech D, York AG, Millett-Sikking A, Testa I
Nat. Methods 21 (5) 882-888 [2024-05-00; online 2024-02-23]
Ilaria Testa SciLifeLab Fellow
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Scuphr: A probabilistic framework for cell lineage tree reconstruction.
Koptagel H, Jun SH, Hård J, Lagergren J
PLoS Comput Biol 20 (5) e1012094 [2024-05-00; online 2024-05-09]
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Plasma proteomics for prediction of subclinical coronary artery calcifications in primary prevention.
Royer P, Björnson E, Adiels M, ..., Gummesson A, Bergström G
Am Heart J 271 (-) 55-67 [2024-05-00; online 2024-02-05]
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Ouabain modulates collective cell migration via a Na,K-ATPase activated Ca2+ signal pathway
Brismar H, Senftleben M, Latron E, ..., Edwards S, Ogazon A
Physiology 39 (S1) - [2024-05-00; online 2024-05-00]
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Lessons learned from a multi-data source research collaboration: The mirabegron post-authorization safety study program.
de Vogel S, Seeger JD, Arana A, ..., Appenteng K, Robinson NJ
Pharmacoepidemiol Drug Saf 33 (5) e5799 [2024-05-00; online 2024-04-29]
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Human-aided dispersal and population bottlenecks facilitate parasitism escape in the most invasive mosquito species.
Girard M, Martin E, Vallon L, ..., Valiente Moro C, Minard G
PNAS Nexus 3 (5) pgae175 [2024-05-00; online 2024-04-30]
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Genomic basis of seed colour in quinoa inferred from variant patterns using extreme gradient boosting.
Sandell FL, Holzweber T, Street NR, Dohm JC, Himmelbauer H
Plant Biotechnol J 22 (5) 1312-1324 [2024-05-00; online 2024-01-11]
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Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits.
Keaton JM, Kamali Z, Xie T, ..., Snieder H, Warren HR
Nat. Genet. 56 (5) 778-791 [2024-05-00; online 2024-04-30]
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Generation of Anterior Segment of the Eye Cells from hiPSCs in Microfluidic Platforms.
Koçak G, Uyulgan S, Polatlı E, ..., Utine CA, Güven S
Adv Biol (Weinh) 8 (5) e2400018 [2024-05-00; online 2024-04-19]
Adil Mardinoglu SciLifeLab Fellow
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Gastrointestinal cancer precursor risk and mortality in pancreatic intraductal papillary mucinous neoplasms: a nationwide cohort study.
Vujasinovic M, Elbe P, Ekheden I, ..., Löhr JM, Ludvigsson JF
Scand. J. Gastroenterol. 59 (5) 600-607 [2024-05-00; online 2024-02-13]
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Fluorescently labeled prey surrogates in combination with fluorescence‐activated cell sorting successfully discriminate actively feeding mixotrophs in a lake water sample
Florenza J, Divne A, Bertilsson S
Limnol. Oceanogr. 69 (5) 1030-1044 [2024-05-00; online 2024-03-13]
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FEV 1 and FVC as Robust Risk Factors for Cardiovascular Disease and Mortality: Insights From a Large Population Study
Rydell A, Janson C, Lisspers K, Lin YT, Ärnlöv J
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Disease staging of Alzheimer's disease using a CSF-based biomarker model.
Salvadó G, Horie K, Barthélemy NR, ..., Bateman RJ, Hansson O
Nat Aging 4 (5) 694-708 [2024-05-00; online 2024-03-21]
DDLS Fellow Jacob W Vogel
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Cost-effectiveness of therapist-assisted internet-delivered psychological therapies for PTSD differing in trauma focus in England: an economic evaluation based on the STOP-PTSD trial.
Penington E, Wild J, Warnock-Parkes E, ..., Tsiachristas A, Ehlers A
Lancet Psychiatry 11 (5) 339-347 [2024-05-00; online 2024-03-27]
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Colonization factors of human and animal-specific enterotoxigenic Escherichia coli (ETEC).
von Mentzer A, Svennerholm AM
Trends Microbiol. 32 (5) 448-464 [2024-05-00; online 2023-12-04]
Astrid von Mentzer DDLS Fellow
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Cellular energy regulates mRNA degradation in a codon-specific manner.
Tomaz da Silva P, Zhang Y, Theodorakis E, ..., Pelechano V, Gagneur J
Mol Syst Biol 20 (5) 506-520 [2024-05-00; online 2024-03-15]
SciLifeLab Fellow Vicente Pelechano
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COVID-19 vaccine uptake among young adults: Influence of asthma and sociodemographic factors.
Ödling M, Andersson N, Ekström S, ..., Melén E, Kull I
J Allergy Clin Immunol Glob 3 (2) 100231 [2024-05-00; online 2024-02-20]
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Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.
Shrine N, Guyatt AL, Erzurumluoglu AM, ..., Tobin MD, Wain LV
Nat. Genet. 56 (5) 1032-1033 [2024-05-00; online 2024-04-20]
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Arachidonic acid and docosahexaenoic acid levels correlate with the inflammation proteome in extremely preterm infants.
Klevebro S, Kebede Merid S, Sjöbom U, ..., Hellström A, Nilsson AK
Clin Nutr 43 (5) 1162-1170 [2024-05-00; online 2024-04-03]
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Abstract 2079: Single-cell And Spatially Resolved Transcriptome Analysis Reveals A Novel Lncrna Regulator Of Human Atherosclerosis
Pauli J, Schanda S, Wu Z, ..., Eckstein HH, Maegdefessel L
Arterioscler. Thromb. Vasc. Biol. 44 (Suppl_1) - [2024-05-00; online 2024-05-00]
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MassiveFold: unveiling AlphaFold’s hidden potential with optimized and parallelized massive sampling
Raouraoua N, Mirabello C, Véry T, ..., Lensink M, Brysbaert G
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Drivers Underlying Metastasis and Relapse in Medulloblastoma and Targeting Strategies.
Holmberg KO, Borgenvik A, Zhao M, Giraud G, Swartling FJ
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Clonal Hematopoiesis of Indeterminate Potential With Loss of Tet2 Enhances Risk for Atrial Fibrillation Through Nlrp3 Inflammasome Activation.
Lin AE, Bapat AC, Xiao L, ..., Ellinor PT, Ebert BL
Circulation 149 (18) 1419-1434 [2024-04-30; online 2024-02-15]
Abhishek Niroula DDLS Fellow
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PARKIN is not required to sustain OXPHOS function in adult mammalian tissues.
Filograna R, Gerlach J, Choi HN, ..., Svenningsson P, Larsson NG
NPJ Parkinsons Dis 10 (1) 93 [2024-04-29; online 2024-04-29]
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Mapping Lesions that Cause Psychosis to a Human Brain Circuit and Proposed Stimulation Target
Pines AR, Frandsen SB, Drew W, ..., Silbersweig D, Siddiqi SH
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Local Immune Activation and Age Impact on Humoral Immunity in Mice, with a Focus on IgG Sialylation.
Gupta P, Sághy T, Bollmann M, ..., Corciulo C, Engdahl C
Vaccines (Basel) 12 (5) - [2024-04-29; online 2024-04-29]
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Loss of NEDD8 in cancer cells causes vulnerability to immune checkpoint blockade in triple-negative breast cancer.
Papakyriacou I, Kutkaite G, Rúbies Bedós M, ..., Menden MP, Mao Y
Nat Commun 15 (1) 3581 [2024-04-27; online 2024-04-27]
SciLifeLab Fellow Yumeng Mao
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Tissue and cellular spatiotemporal dynamics in colon aging.
Daly AC, Cambuli F, Äijö T, ..., Regev A, Vickovic S
bioRxiv - (-) - [2024-04-26; online 2024-04-26]
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Front Plant Sci 15 (-) 1358490 [2024-04-26; online 2024-04-26]
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Deep learning insights into the architecture of the mammalian egg-sperm fusion synapse.
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Elife 13 (-) - [2024-04-26; online 2024-04-26]
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Nat Commun 15 (1) 3475 [2024-04-24; online 2024-04-24]
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Proc. Natl. Acad. Sci. U.S.A. 121 (17) e2317680121 [2024-04-23; online 2024-04-18]
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Combined Metabolic Activators with Different NAD+ Precursors Improve Metabolic Functions in the Animal Models of Neurodegenerative Diseases.
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Biomedicines 12 (4) - [2024-04-22; online 2024-04-22]
Adil Mardinoglu Saeed Shoaie SciLifeLab Fellow
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iScience 27 (4) 109509 [2024-04-19; online 2024-03-14]
Avlant Nilsson DDLS Fellow
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iScience 27 (4) 109344 [2024-04-19; online 2024-02-28]
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Durinova A, Smutna L, Barta P, ..., Pavek P, Trejtnar F
EJNMMI Radiopharm Chem 9 (1) 32 [2024-04-18; online 2024-04-18]
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Chung T, Salazar A, Harm G, ..., Carroll LM, Kovac J
Applied and environmental microbiology 90 (4) e0177823 [2024-04-17; online 2024-03-12]
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Edelbroek B, Kjellin J, Biryukova I, ..., Friedländer MR, Söderbom F
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J Immunother Cancer 12 (4) - [2024-04-11; online 2024-04-11]
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Kukanja P, Langseth CM, Rubio Rodríguez-Kirby LA, ..., Nilsson M, Castelo-Branco G
Cell 187 (8) 1990-2009.e19 [2024-04-11; online 2024-03-20]
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Reviewer #2 (Public Review): Deep learning insights into the architecture of the mammalian egg-sperm fusion synapse
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Rentzsch P, Kollotzek A, Mohammadi P, Lappalainen T
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Postel Z, Van Rossum F, Godé C, Schmitt E, Touzet P
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Deep learning insights into the architecture of the mammalian egg-sperm fusion synapse
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Author response: Deep learning insights into the architecture of the mammalian egg-sperm fusion synapse
Elofsson A, Han L, Bianchi E, Wright GJ, Jovine L
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Huseby DL, Cao S, Zamaratski E, ..., Hughes D, Karlén A
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J. Exp. Clin. Cancer Res. 43 (1) 107 [2024-04-09; online 2024-04-09]
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Pharmaceutics 16 (4) - [2024-04-08; online 2024-04-08]
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Int J Mol Sci 25 (7) - [2024-04-06; online 2024-04-06]
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Adil Mardinoglu SciLifeLab Fellow
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Int J Mol Sci 25 (7) - [2024-04-05; online 2024-04-05]
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Activity modulation in anaerobic ribonucleotide reductases: nucleotide binding to the ATP-cone allosterically mediates substrate binding to the active site
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Res Sq - (-) - [2024-04-04; online 2024-04-04]
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Proc. Natl. Acad. Sci. U.S.A. 121 (14) e2320413121 [2024-04-02; online 2024-03-26]
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Angewandte Chemie 136 (14) - [2024-04-02; online 2024-02-29]
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Rapid and Bifunctional Chemoselective Metabolome Analysis of Liver Disease Plasma Using the Reagent 4‐Nitrophenyl‐2‐azirine
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Ekvall M, Bergenstråhle L, Andersson A, ..., Käll L, Lundeberg J
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Conserv Genet 25 (2) 513-531 [2024-04-00; online 2024-01-20]
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Prieto-Díaz R, Fojo-Carballo H, Majellaro M, ..., Gutiérrez-de-Terán H, Sotelo E
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Estrogen receptor activation remodels TEAD1 gene expression to alleviate hepatic steatosis.
Sommerauer C, Gallardo-Dodd CJ, Savva C, ..., Williams C, Kutter C
Mol Syst Biol 20 (4) 374-402 [2024-04-00; online 2024-03-08]
Claudia Kutter Erdinc Sezgin SciLifeLab Fellow
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Effective data-driven collective variables for free energy calculations from metadynamics of paths.
Müllender L, Rizzi A, Parrinello M, Carloni P, Mandelli D
PNAS Nexus 3 (4) pgae159 [2024-04-00; online 2024-04-12]
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Diverse mechanisms control amino acid-dependent environmental alkalization by Candida albicans.
Silao FGS, Valeriano VD, Uddström E, Falconer E, Ljungdahl PO
Mol. Microbiol. 121 (4) 696-716 [2024-04-00; online 2024-01-04]
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Direct Salmonella injection into enteroid cells allows the study of host-pathogen interactions in the cytosol with high spatiotemporal resolution.
Ernst C, Andreassen PR, Giger GH, ..., Hardt WD, Vorholt JA
PLoS Biol. 22 (4) e3002597 [2024-04-00; online 2024-04-29]
Mikael Sellin SciLifeLab Fellow
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Tesi B, Robinson KL, Abel F, ..., Taylan F, Nordgren A
Lancet Reg Health Eur 39 (-) 100881 [2024-04-00; online 2024-03-19]
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Despite structural identity, ace-1 heterogenous duplication resistance alleles are quite diverse in Anopheles mosquitoes.
Claret JL, Di-Liegro M, Namias A, ..., Milesi P, Labbé P
Heredity (Edinb) 132 (4) 179-191 [2024-04-00; online 2024-01-27]
Pascal Milesi SciLifeLab Fellow
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Frommelt F, Fossati A, Uliana F, ..., Ciuffa R, Gstaiger M
Nat. Methods 21 (4) 635-647 [2024-04-00; online 2024-03-26]
Andrea Fossati DDLS Fellow
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Edsjö A, Gisselsson D, Staaf J, ..., Cavelier L, Rosenquist R
Mol. Aspects Med. 96 (-) 101250 [2024-04-00; online 2024-02-07]
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Sakakibara S, Pazzagli L, Linder M
Pharmacoepidemiol Drug Saf 33 (4) e5780 [2024-04-00; online 2024-03-21]
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Compound Absorption in Polymer Devices Impairs the Translatability of Preclinical Safety Assessments.
Kemas AM, Zandi Shafagh R, Taebnia N, ..., Hofmann U, Lauschke VM
Adv Healthc Mater 13 (11) e2303561 [2024-04-00; online 2023-12-10]
PubMed DOI Crossref
Cancer-associated fibroblasts rewire the estrogen receptor response in luminal breast cancer, enabling estrogen independence.
Reid SE, Pantaleo J, Bolivar P, ..., Seashore-Ludlow B, Pietras K
Oncogene 43 (15) 1113-1126 [2024-04-00; online 2024-02-22]
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CD40 stimulation via CD40 ligand enhances adenovirus-mediated tumour immunogenicity including 'find-me', 'eat-me', and 'kill-me' signalling.
Naseri S, Cordova MM, Wenthe J, ..., Loskog A, Ullenhag GJ
J. Cell. Mol. Med. 28 (7) e18162 [2024-04-00; online 2024-03-18]
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Biomarker-based staging of Alzheimer disease: rationale and clinical applications.
Therriault J, Schindler SE, Salvadó G, ..., Jack CR, Rosa-Neto P
Nat Rev Neurol 20 (4) 232-244 [2024-04-00; online 2024-03-01]
DDLS Fellow Jacob W Vogel
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Automated model building and protein identification in cryo-EM maps.
Jamali K, Käll L, Zhang R, ..., Kimanius D, Scheres SHW
Nature 628 (8007) 450-457 [2024-04-00; online 2024-02-26]
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A pan-genomic approach reveals novel Sulfurimonas clade in the ferruginous meromictic Lake Pavin.
Biderre-Petit C, Courtine D, Hennequin C, ..., Divne AM, Hochart C
Mol Ecol Resour 24 (3) e13923 [2024-04-00; online 2024-01-08]
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Modulator of TMB-associated immune infiltration (MOTIF) predicts immunotherapy response and guides combination therapy.
Qian ZY, Pan YQ, Li XX, ..., Wang ZX, Xu RH
Sci Bull (Beijing) 69 (6) 803-822 [2024-03-30; online 2024-01-19]
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Two Different Strategies for Stabilization of Brain Tissue and Extraction of Neuropeptides.
Fridjonsdottir E, Nilsson A, Fricker LD, Andrén PE
Methods in molecular biology (Clifton, N.J.) 2758 (-) 49-60 [2024-03-29; online 2024-03-29]
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Gene-expression memory-based prediction of cell lineages from scRNA-seq datasets.
Eisele AS, Tarbier M, Dormann AA, Pelechano V, Suter DM
Nat Commun 15 (1) 2744 [2024-03-29; online 2024-03-29]
DDLS Fellow Marcel Tarbier SciLifeLab Fellow
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Karami M, Soltani Mohammadi A, Martin M, ..., Patro R, Sahlin K
Bioinformatics 40 (4) - [2024-03-29; online 2024-04-05]
Kristoffer Sahlin SciLifeLab Fellow
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Characterizing exposure-outcome associations to identify biologically relevant cutoffs.
Huang J, Olsson T, Kockum I
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Best practices for the execution, analysis, and data storage of plant single-cell/nucleus transcriptomics.
Grones C, Eekhout T, Shi D, ..., Libault M, De Rybel B
Plant Cell 36 (4) 812-828 [2024-03-29; online 2024-01-17]
PubMed DOI Crossref
Refining risk prediction in pediatric acute lymphoblastic leukemia through DNA methylation profiling.
Mosquera Orgueira A, Krali O, Pérez Míguez C, ..., Schmiegelow K, Nordlund J
Clin Epigenetics 16 (1) 49 [2024-03-28; online 2024-03-28]
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Perspective of Creating a Low-Cost Medical Assistant Robot Based on the WafflePI4 Platform with a Palm Vein Pattern Scanner
Anufriiev V, Kravchuk O, Levchenko Y, ..., Linnyk E, Glukhov O
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DOI Crossref
Nematocida displodere Mechanosensitive Ion Channel of Small Conductance 2 assembles into a unique 6-channel super-structure in vitro
Berg A, Berntsson RPA, Barandun J
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Jonas Barandun SciLifeLab Fellow
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Low coverage of species constrains the use of DNA barcoding to assess mosquito biodiversity.
Moraes Zenker M, Portella TP, Pessoa FAC, Bengtsson-Palme J, Galetti PM
Sci Rep 14 (1) 7432 [2024-03-28; online 2024-03-28]
DDLS Fellow
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Long-Term Survival and Immune Response Dynamics in Melanoma Patients Undergoing TAPCells-Based Vaccination Therapy.
Tittarelli A, Pereda C, Gleisner MA, ..., Larrondo M, Salazar-Onfray F
Vaccines (Basel) 12 (4) - [2024-03-27; online 2024-03-27]
DOI Crossref
Landscape of microRNA and target expression variation and covariation in single mouse embryonic stem cells
Tarbier M, Mackowiak SD, Sekar V, ..., Biryukova I, Friedländer MR
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DDLS Fellow Marc Friedländer Marcel Tarbier SciLifeLab Fellow
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A research data management (RDM) community for ELIXIR
D'Anna F, Jareborg N, Jetten M, ..., Vondrasek J, Andrabi M
F1000Res 13 (-) 230 [2024-03-27; online 2024-03-27]
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Unboxing the network among long non-coding RNAs and TGF-β signaling in cancer.
Rodrigues-Junior DM, Moustakas A
Ups. J. Med. Sci. 129 (-) - [2024-03-26; online 2024-03-26]
PubMed DOI Crossref
Salmonella T3SS-2 virulence enhances gut-luminal colonization by enabling chemotaxis-dependent exploitation of intestinal inflammation.
Gül E, Huuskonen J, Abi Younes A, ..., Bakkeren E, Hardt WD
Cell Reports 43 (3) 113925 [2024-03-26; online 2024-03-07]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
ProQ-dependent activation of Salmonella virulence genes mediated by post-transcriptional control of PhoP synthesis.
Bergman S, Andresen L, Kjellin J, ..., Sellin ME, Holmqvist E
mSphere 9 (3) e0001824 [2024-03-26; online 2024-02-27]
Mikael Sellin SciLifeLab Fellow
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Mosaic deletion of claudin-5 reveals rapid non-cell-autonomous consequences of blood-brain barrier leakage.
Vázquez-Liébanas E, Mocci G, Li W, ..., Betsholtz C, Mäe MA
Cell Reports 43 (3) 113911 [2024-03-26; online 2024-03-05]
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Assessing the Fate of Benzophenone-Type UV Filters and Transformation Products during Soil Aquifer Treatment: The Biofilm Compartment as Bioaccumulator and Biodegrader in Porous Media.
Jou-Claus S, Rodríguez-Escales P, Martínez-Landa L, ..., Quintana G, Valhondo C
Environ. Sci. Technol. 58 (12) 5472-5482 [2024-03-26; online 2024-03-11]
DOI Crossref
Perturbations in eIF3 subunit stoichiometry alter expression of ribosomal proteins and key components of the MAPK signaling pathway
Herrmannová A, Jelínek J, Pospíšilová K, ..., Topisirovic I, Valášek LS
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PubMed DOI Crossref
Novel Synonymous and Deep Intronic Variants Causing Primary and Secondary Pyruvate Dehydrogenase Complex Deficiency.
Bruhn H, Naess K, Ygberg S, ..., Wedell A, Wredenberg A
Hum. Mutat. 2024 (-) 1611838 [2024-03-25; online 2024-03-25]
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NEDD8 loss causes cancer vulnerability to immune checkpoint blockade in triple-negative breast cancer
Mao Y, Papakyriacou I, Kutkaite G, ..., Alford L, Menden M
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SciLifeLab Fellow Yumeng Mao
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Braeuning A, Balaguer P, Bourguet W, ..., Wewer N, Zalko D
Front Toxicol 6 (-) 1394396 [2024-03-25; online 2024-03-25]
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Author Response: Perturbations in eIF3 subunit stoichiometry alter expression of ribosomal proteins and key components of the MAPK signaling pathway
Herrmannová A, Jelínek J, Pospíšilová K, ..., Topisirovic I, Valášek LS
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A Comprehensive Analysis of the Effect of A>I(G) RNA-Editing Sites on Genotoxic Drug Response and Progression in Breast Cancer.
Bernal YA, Blanco A, Sagredo EA, ..., Marcelain K, Armisén R
Biomedicines 12 (4) - [2024-03-25; online 2024-03-25]
PubMed DOI Crossref
Influence of Molecular Design on the Tumor Targeting and Biodistribution of PSMA-Binding Tracers Labeled with Technetium-99m.
Bezverkhniaia E, Kanellopoulos P, Rosenström U, Tolmachev V, Orlova A
Int J Mol Sci 25 (7) - [2024-03-23; online 2024-03-23]
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Abstract 7287: High-grade serous ovarian carcinoma detected with TP53 mutation panel and SiMSen-Seq
Widjaja AO, Micallef P, Ulfenborg B, ..., Linder A, Sundfeldt K
Cancer Res. 84 (6_Supplement) 7287-7287 [2024-03-22; online 2024-03-22]
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Abstract 3100: Interactive analysis of drug testing data for functional precision oncology with Breeze 2.0
Potdar S, Ianevski F, Ianevski A, ..., Aittokallio T, Saarela J
Cancer Res. 84 (6_Supplement) 3100-3100 [2024-03-22; online 2024-03-22]
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Enhanced EMC-Advantages of partially known orientations in x-ray single particle imaging.
Wollter A, De Santis E, Ekeberg T, Marklund EG, Caleman C
J Chem Phys 160 (11) - [2024-03-21; online 2024-03-20]
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Contrasting segregation patterns among endogenous retroviruses across the koala population.
Lillie M, Pettersson M, Jern P
Commun Biol 7 (1) 350 [2024-03-21; online 2024-03-21]
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Epigenetic modulators link mitochondrial redox homeostasis to cardiac function in a sex-dependent manner.
ElBeck Z, Hossain MB, Siga H, ..., Végvári Á, Betsholtz C
Nat Commun 15 (1) 2358 [2024-03-20; online 2024-03-20]
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Cluster-free annotation of single cells using Earth mover’s distance-based classification
Forlin R, Tajvar P, Wang N, Dimarogonas D, Brodin P
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DDLS-WASP
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Caveolin-1 gene expression provides additional prognostic information combined with PAM50 risk of recurrence (ROR) score in breast cancer.
Godina C, Belting M, Vallon-Christersson J, ..., Bosch A, Jernström H
Sci Rep 14 (1) 6675 [2024-03-20; online 2024-03-20]
PubMed DOI Crossref
Neural network informed photon filtering reduces fluorescence correlation spectroscopy artifacts.
Seltmann A, Carravilla P, Reglinski K, Eggeling C, Waithe D
Biophys. J. 123 (6) 745-755 [2024-03-19; online 2024-02-20]
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Near-wall depletion and layering affect contact line friction of multicomponent liquids
Pellegrino M, Hess B
Phys. Rev. Fluids 9 (3) - [2024-03-19; online 2024-03-19]
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Multi-omics analysis of aggregative multicellularity
Edelbroek B, Orzechowski Westholm J, Bergquist J, Söderbom F
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MicroRNA-155 mediates multiple gene regulations pertinent to the role of human adipose-derived mesenchymal stem cells in skin regeneration.
Shahin H, Belcastro L, Das J, ..., Elmasry M, El-Serafi AT
Front Bioeng Biotechnol 12 (-) 1328504 [2024-03-18; online 2024-03-18]
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Identification of novel and potent inhibitors of SARS-CoV-2 main protease from DNA-encoded chemical libraries
Akaberi D, Pourghasemi Lati M, Krambrich J, ..., Verho O, Lennerstrand J
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DOI Crossref
Chloroplastic ascorbate acts as a regulatory hub in plant metabolism regardless of oxidative stress
Tóth D, Tengölics R, Aarabi F, ..., Papp B, Tóth SZ
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Paul Hudson SciLifeLab Fellow
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Glutamine deprivation alters TGF-β signaling in hepatocellular carcinoma
Gélabert C, Campisano S, Golán IC, ..., Moustakas A, Caja L
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PubMed DOI Crossref
Is GBA1 T369M not a risk factor for Parkinson's disease in the Swedish population?
Brolin KA, Bäckström D, Wallenius J, ..., Hansson O, Swanberg M
medRxiv - (-) - [2024-03-16; online 2024-03-16]
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Maintenance of cell wall remodeling and vesicle production are connected in Mycobacterium tuberculosis
Salgueiro V, Bertol J, Gutierrez C, ..., Sanz J, Prados-Rosales R
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PubMed DOI Crossref
Influence of divalent cations on the extraction of organic acids in coffee determined by GC-MS and NMR.
Bratthäll T, Figueira J, Nording ML
Heliyon 10 (5) e26625 [2024-03-15; online 2024-02-17]
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Genetic liability for anxiety associates with treatment response to the monoamine stabilizer OSU6162 in alcohol dependence
Hong MG, Khemiri L, Guterstam J, ..., Jayaram-Lindström N, Melas PA
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PubMed DOI Crossref
Folded Alpha Helical Putative New Proteins from Apilactobacillus kunkeei.
Ye W, Krishna Behra PR, Dyrhage K, ..., Andersson SGE, Jemth P
J. Mol. Biol. 436 (6) 168490 [2024-03-15; online 2024-02-13]
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Comparison of SARS-CoV-2 spike-specific IgA and IgG in nasal secretions, saliva and serum.
Bladh O, Aguilera K, Marking U, ..., Thålin C, Åberg M
Front Immunol 15 (-) 1346749 [2024-03-15; online 2024-03-15]
PubMed DOI Crossref
Boundary cap neural crest stem cells promote angiogenesis after transplantation to avulsed dorsal roots in mice and induce migration of endothelial cells in 3D printed scaffolds.
Trolle C, Han Y, Mutt SJ, Christoffersson G, Kozlova EN
Neurosci. Lett. 826 (-) 137724 [2024-03-15; online 2024-03-11]
Gustaf Christoffersson SciLifeLab Fellow
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Author Response: Maintenance of cell wall remodeling and vesicle production are connected in Mycobacterium tuberculosis
Salgueiro V, Bertol J, Gutierrez C, ..., Sanz J, Prados-Rosales R
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DOI Crossref
A distinctive tumor compartment in pancreatic lobules defined by nascent stroma and classical tumor cell phenotype
Söderqvist S, Viljamaa A, Geyer N, ..., Moro CF, Gerling M
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PubMed DOI Crossref
ZP2 cleavage blocks polyspermy by modulating the architecture of the egg coat.
Nishio S, Emori C, Wiseman B, ..., Ikawa M, Jovine L
Cell 187 (6) 1440-1459.e24 [2024-03-14; online 2024-03-16]
DOI Crossref
Spatial Dynamics of the Developing Human Heart
Lázár E, Mauron R, Andrusivová Ž, ..., Adameyko I, Lundeberg J
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PubMed DOI Crossref
Regulation of meiotic telomere dynamics through membrane fluidity promoted by AdipoR2-ELOVL2.
Zhang J, Ruiz M, Bergh PO, ..., Pilon M, Shibuya H
Nat Commun 15 (1) 2315 [2024-03-14; online 2024-03-14]
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Medically relevant tandem repeats in nanopore sequencing of control cohorts
De Coster W, Höijer I, Bruggeman I, ..., Ameur A, Rademakers R
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PubMed DOI Crossref
Transcriptomic and proteomic profiles of fetal versus adult mesenchymal stromal cells and mesenchymal stromal cell-derived extracellular vesicles.
Gençer EB, Lor YK, Abomaray F, ..., Walther-Jallow L, Götherström C
Stem Cell Res Ther 15 (1) 77 [2024-03-13; online 2024-03-13]
PubMed DOI Crossref
The impact of genetically controlled splicing on exon inclusion and protein structure.
Einson J, Minaeva M, Rafi F, Lappalainen T
PLoS ONE 19 (3) e0291960 [2024-03-13; online 2024-03-13]
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Structural constraints on the emergence of oscillations in multi-population neural networks.
Zang J, Liu S, Helson P, Kumar A
Elife 12 (-) - [2024-03-13; online 2024-03-13]
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Structural constraints on the emergence of oscillations in multi-population neural networks
Zang J, Liu S, Helson P, Kumar A
Elife 12 (-) - [2024-03-13; online 2024-03-13]
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Identification of a new gregarine parasite associated with mass mortality events of freshwater pearl mussels (Margaritifera margaritifera) in Sweden.
Alfjorden A, Onut-Brännström I, Wengström N, ..., Persson BD, Burki F
J. Eukaryot. Microbiol. 71 (3) e13021 [2024-03-13; online 2024-03-13]
Fabien Burki SciLifeLab Fellow
PubMed DOI Crossref
Genome wide association study in Swedish Labrador retrievers identifies genetic loci associated with hip dysplasia and body weight.
Kieler IN, Persson SM, Hagman R, ..., Lindblad-Toh K, Arendt ML
Sci Rep 14 (1) 6090 [2024-03-13; online 2024-03-13]
PubMed DOI Crossref
Transcriptome Analysis Reveals Distinct Patterns Between the Invasive and Noninvasive Pituitary Neuroendocrine Tumors.
Jotanovic J, Tebani A, Hekmati N, ..., Pontén F, Casar-Borota O
J Endocr Soc 8 (5) bvae040 [2024-03-12; online 2024-03-01]
DOI Crossref
Ribosomes modulate transcriptome abundance via generalized frameshift and out-of-frame mRNA decay
Zhang Y, Nersisyan L, Fürst E, ..., Piazza I, Pelechano V
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SciLifeLab Fellow
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Neutralizing IFN-γ autoantibodies are rare and pathogenic in HLA-DRB1*15:02 or 16:02 individuals.
Peel JN, Yang R, Le Voyer T, ..., Ku CL, Casanova JL
J. Clin. Invest. 134 (8) - [2024-03-12; online 2024-03-12]
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Vascular characterization reveals immunomodulatory targets for brain metastases.
Lugano R, Dimberg A
Cancer Cell 42 (3) 328-330 [2024-03-11; online 2024-02-15]
DOI Crossref
U-FISH: a universal deep learning approach for accurate FISH spot detection across diverse datasets
Xu W, Cai H, Zhang Q, ..., Ouyang W, Cao G
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DDLS Fellow Wei Ouyang
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Gut Eggerthella lenta promotes the efficacy of resveratrol through reductive metabolism
Dong Z, Yu P, Zhou H, ..., Gu Y, Jiang W
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PubMed DOI Crossref
An efficient protocol for extracting thylakoid membranes and total leaf proteins from Posidonia oceanica and other polyphenol-rich plants.
Charras Q, Rey P, Guillemain D, ..., Rayon C, Jungas C
Plant Methods 20 (1) 38 [2024-03-11; online 2024-03-11]
PubMed DOI Crossref
Cardiac biopsies reveal differences in transcriptomics between left and right ventricle in patients with or without diagnostic signs of heart failure.
Frisk C, Das S, Eriksson MJ, ..., Linde C, Persson B
Sci Rep 14 (1) 5811 [2024-03-09; online 2024-03-09]
PubMed DOI Crossref
Plasma metabolites of a healthy lifestyle in relation to mortality and longevity: Four prospective US cohort studies.
Tessier AJ, Wang F, Liang L, ..., Hu FB, Guasch-Ferré M
Med 5 (3) 224-238.e5 [2024-03-08; online 2024-02-15]
Clemens Wittenbecher DDLS Fellow
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Midbrain Dopaminergic Neuron Development is Regulated by Two Molecularly Distinct Subtypes of Radial Glia Cells
Ásgrímsdóttir ES, Bassini LF, di Val Cervo PR, ..., Toledo EM, Arenas E
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PubMed DOI Crossref
Twenty years on from Developmental Plasticity and Evolution: middle-range theories and how to test them.
Uller T, Milocco L, Isanta-Navarro J, Cornwallis CK, Feiner N
J. Exp. Biol. 227 (Suppl_1) - [2024-03-07; online 2024-03-07]
DDLS Fellow Lisandro Milocco
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Quantifying Fluorescence Lifetime Responsiveness of Environment-Sensitive Probes for Membrane Fluidity Measurements.
Ragaller F, Sjule E, Urem YB, ..., Blom H, Sezgin E
J Phys Chem B 128 (9) 2154-2167 [2024-03-07; online 2024-02-28]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
Protein biomarkers and alternatively methylated cell-free DNA detect early stage pancreatic cancer.
Ben-Ami R, Wang QL, Zhang J, ..., Dor Y, Wolpin BM
Gut 73 (4) 639-648 [2024-03-07; online 2024-03-07]
DDLS Fellow Qiaoli Wang
DOI Crossref
Nuclear RNAi Modulates Influenza A Virus Infectivity By Downregulating Type-I Interferon Response
Huang HC, Nowak I, Lobo V, ..., Angeletti D, Sarshad AA
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PubMed DOI Crossref
Identification of microbial pathogens in Neolithic Scandinavian humans.
Bergfeldt N, Kırdök E, Oskolkov N, ..., Storå J, Götherström A
Sci Rep 14 (1) 5630 [2024-03-07; online 2024-03-07]
PubMed DOI Crossref
Essential role of local antibody distribution in mediating bone-resorbing effects.
Nurkkala-Karlsson M, Lagerquist MK, Gupta P, ..., Mellström D, Engdahl C
Sci Rep 14 (1) 5684 [2024-03-07; online 2024-03-07]
PubMed DOI Crossref
Clonal haematopoiesis of indeterminate potential predicts incident cardiac arrhythmias.
Schuermans A, Vlasschaert C, Nauffal V, ..., Natarajan P, Honigberg MC
Eur. Heart J. 45 (10) 791-805 [2024-03-07; online 2023-11-12]
Abhishek Niroula DDLS Fellow
DOI Crossref
Multi-Omics Profiling Reveals Gene Signatures and Therapeutic Targets in HER2- Guided Gastric Cardia Adenocarcinoma Patients
Wang LD, Xing P, Zhao XK, ..., Gao SG, Chen X
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PubMed DOI Crossref
Investigating the efficacy of green solvents and solvent-free conditions in hydrogen-bonding mediated organocatalyzed model reactions.
Chetty LC, Kruger HG, Arvidsson PI, Naicker T, Govender T
RSC Adv. 14 (12) 7992-7998 [2024-03-06; online 2024-03-07]
PubMed DOI Crossref
AutonoMS: Automated Ion Mobility Metabolomic Fingerprinting.
Reder GK, Bjurström EY, Brunnsåker D, ..., McLean JA, King RD
J. Am. Soc. Mass Spectrom. 35 (3) 542-550 [2024-03-06; online 2024-02-04]
DOI Crossref
An Allosteric Cholesterol Site in Glycine Receptors Characterized Through Molecular Simulations
Jalalypour F, Howard RJ, Lindahl E
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PubMed DOI Crossref
Loss of chromosome Y in regulatory T cells.
Mattisson J, Halvardson J, Davies H, ..., Dumanski JP, Forsberg LA
BMC Genomics 25 (1) 243 [2024-03-05; online 2024-03-05]
PubMed DOI Crossref
Linear epitopes of bony fish β-parvalbumins.
Franciskovic E, Thörnqvist L, Greiff L, Gasset M, Ohlin M
Front Immunol 15 (-) 1293793 [2024-03-05; online 2024-03-05]
PubMed DOI Crossref
Immuno-oncological effects of standard anticancer agents and commonly used concomitant drugs: an in vitro assessment.
Selvin T, Berglund M, Lenhammar L, ..., Fryknäs M, Andersson CR
BMC Pharmacol Toxicol 25 (1) 25 [2024-03-05; online 2024-03-05]
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Guselkumab in Patients with Scalp Psoriasis: A post hoc Analysis of the VOYAGE 2 Phase III Randomized Clinical Trial.
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Conformal prediction enables disease course prediction and allows individualized diagnostic uncertainty in multiple sclerosis
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The Calvin Benson cycle in bacteria: New insights from systems biology.
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Patient-Centric Quantitative Microsampling for Accurate Determination of Urine Albumin to Creatinine Ratio (UACR) in a Clinical Setting.
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Asymmetric T-cell division: insights from cutting-edge experimental techniques and implications for immunotherapy.
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VE-cadherin junction dynamics in initial lymphatic vessels promotes lymph node metastasis.
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Uncovering driver genes in breast cancer through an innovative machine learning mutational analysis method.
Taheri G, Habibi M
Comput Biol Med 171 (-) 108234 [2024-03-00; online 2024-02-29]
DDLS Fellow Golnaz Taheri
PubMed DOI Crossref
The risk of venous thromboembolism in oral contraceptive users: the role of genetic factors-a prospective cohort study of 240,000 women in the UK Biobank.
Lo Faro V, Johansson T, Johansson Å
Am J Obstet Gynecol 230 (3) 360.e1-360.e13 [2024-03-00; online 2023-09-19]
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The regulation of methylation on the Z chromosome and the identification of multiple novel Male Hyper-Methylated regions in the chicken.
Höglund A, Henriksen R, Churcher AM, ..., Jensen P, Wright D
PLoS Genet 20 (3) e1010719 [2024-03-00; online 2024-03-08]
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The impact of circulating protein levels identified by affinity proteomics on short-term, overall breast cancer risk.
Grassmann F, Mälarstig A, Dahl L, ..., Schwenk JM, Czene K
Br. J. Cancer 130 (4) 620-627 [2024-03-00; online 2023-12-22]
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The immunopathological landscape of human pre-TCRα deficiency: From rare to common variants.
Materna M, Delmonte OM, Bosticardo M, ..., Casanova JL, Béziat V
Science (New York, N.Y.) 383 (6686) eadh4059 [2024-03-00; online 2024-03-01]
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The exon-junction complex helicase eIF4A3 holds therapeutic potential in acute myeloid leukemia.
Miliara S, Cozzi E, Zhong X, ..., Bartek J, Kanellis DC
Leukemia 38 (3) 663-666 [2024-03-00; online 2023-11-30]
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The association of the RSC remodeler complex with chromatin is influenced by the prefoldin-like Bud27 and determines nucleosome positioning and polyadenylation sites usage in Saccharomyces cerevisiae.
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Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1867 (1) 194995 [2024-03-00; online 2023-11-13]
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The airway microbiota in siblings with primary ciliary dyskinesia: Related factors and correlation with clinical characteristics.
Ademhan Tural D, Kasikci M, Eryilmaz Polat S, ..., Diker KS, Ozcelik U
Pediatr Pulmonol 59 (3) 695-706 [2024-03-00; online 2023-12-13]
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Ten simple rules for pushing boundaries of inclusion at academic events.
Hall SM, Kochin D, Carne C, ..., Thompson R, Sharan M
PLoS Comput Biol 20 (3) e1011797 [2024-03-00; online 2024-03-01]
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Reconstruction, simulation and analysis of enzyme-constrained metabolic models using GECKO Toolbox 3.0.
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Nat Protoc 19 (3) 629-667 [2024-03-00; online 2024-01-18]
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Prevalence of SARS-CoV-2 infections among Swedish healthcare workers on duty in December 2023.
Aguilera K, Bladh O, Marking U, ..., Alm JJ, Thålin C
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Predicting the future of our oceans-Evaluating genomic forecasting approaches in marine species.
Layton KKS, Brieuc MSO, Castilho R, ..., Vasemägi A, Bradbury IR
Glob Chang Biol 30 (3) e17236 [2024-03-00; online 2024-03-23]
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Population genetics for insect conservation and control
Beaurepaire AL, Webster MT, Neumann P
Conservat Sci and Prac 6 (3) - [2024-03-00; online 2024-02-27]
PubMed DOI Crossref
PACMan: A software package for automated single-cell chlorophyll fluorometry.
Pontén O, Xiao L, Kutter J, ..., Wählby C, Behrendt L
Cytometry A 105 (3) 203-213 [2024-03-00; online 2023-10-20]
Lars Behrendt SciLifeLab Fellow
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P13 Acquired ficolin-3 deficiency in patients with systemic lupus erythematosus
Lindelöf L, Rantapää-Dahlqvist S, Lundtoft C, ..., Svenungsson E, Eriksson O
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O16 pQTL analysis of ficolin-3 activity reveals a link between the lectin pathway of complement and hematological disease manifestations in systemic lupus erythematosus
Lindelöf L, Rantapää-Dahlqvist S, Lundtoft C, ..., Svenungsson E, Eriksson O
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Neurophysiological treatment effects of mesdopetam, pimavanserin and clozapine in a rodent model of Parkinson's disease psychosis.
Stan TL, Ronaghi A, Barrientos SA, ..., Sahlholm K, Petersson P
Neurotherapeutics 21 (2) e00334 [2024-03-00; online 2024-02-16]
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Kupffer cells dictate hepatic responses to the atherogenic dyslipidemic insult.
Di Nunzio G, Hellberg S, Zhang Y, ..., Olofsson PS, Malin SG
Nat Cardiovasc Res 3 (3) 356-371 [2024-03-00; online 2024-03-11]
PubMed DOI Crossref
Genetic drivers of heterogeneity in type 2 diabetes pathophysiology.
Suzuki K, Hatzikotoulas K, Southam L, ..., Morris AP, Zeggini E
Nature 627 (8003) 347-357 [2024-03-00; online 2024-02-19]
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Genetic constraints in genes exhibiting splicing plasticity in facultative diapause.
Steward RA, Pruisscher P, Roberts KT, Wheat CW
Heredity (Edinb) 132 (3) 142-155 [2024-03-00; online 2024-01-30]
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Enhancer mutations modulate the severity of chemotherapy-induced myelosuppression.
Zhigulev A, Norberg Z, Cordier J, ..., Gréen H, Sahlén P
Life Sci. Alliance 7 (3) - [2024-03-00; online 2024-01-16]
PubMed DOI Crossref
Effect of Aerobic Exercise and Time-Restricted Feeding on Metabolic Markers and Circadian Rhythm in Mice Fed with the High-Fat Diet.
Raza GS, Kaya Y, Stenbäck V, ..., Herzig KH, Mäkelä KA
Mol Nutr Food Res 68 (5) e2300465 [2024-03-00; online 2024-02-22]
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Drug repurposing platform for deciphering the druggable SARS-CoV-2 interactome.
Bogacheva MS, Kuivanen S, Potdar S, ..., Pietiäinen V, Vapalahti O
Antiviral Res. 223 (-) 105813 [2024-03-00; online 2024-01-24]
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Delayed treatment effect predicting (DTEP) model for guiding immuno-oncology trial designs
Qian ZY, Duan CY, Cao PH, ..., Xu RH, Wang ZX
Medicine Plus 1 (1) 100006 [2024-03-00; online 2024-03-00]
PubMed DOI Crossref
DEPICTER: Deep representation clustering for histology annotation.
Chelebian E, Avenel C, Ciompi F, Wählby C
Comput Biol Med 170 (-) 108026 [2024-03-00; online 2024-01-26]
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Comparison of high-throughput single-cell RNA-seq methods for ex vivo drug screening.
Gezelius H, Enblad AP, Lundmark A, ..., Andersson C, Nordlund J
NAR Genomics and Bioinformatics 6 (1) lqae001 [2024-03-00; online 2024-01-29]
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Association of Somatic TET2 Mutations With Giant Cell Arteritis.
Robinette ML, Weeks LD, Kramer RJ, ..., Rao DA, Ebert BL
Arthritis & rheumatology (Hoboken, N.J.) 76 (3) 438-443 [2024-03-00; online 2024-02-02]
Abhishek Niroula DDLS Fellow
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Antibiotic use during pregnancy in Sweden: A nationwide utilization study covering 2007-2019.
Nakitanda AO, Odsbu I, Pasternak B, Karlsson P, Pazzagli L
Acta Obstet Gynecol Scand 103 (3) 531-539 [2024-03-00; online 2023-12-18]
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Amyloid-β deposits in human astrocytes contain truncated and highly resistant proteoforms.
Beretta C, Svensson E, Dakhel A, ..., Michno W, Erlandsson A
Mol Cell Neurosci 128 (-) 103916 [2024-03-00; online 2024-01-19]
SciLifeLab Fellow Wojciech Michno
PubMed DOI Crossref
A D-Y Shaped Neuropeptide Y Mimetic Peptide-Dye Self-Assembly with Maximal Emission Beyond 1300 nm and Glioma Mitochondrial Activity Modulation.
Li Y, He X, Wang P, ..., Wu A, Li J
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PubMed DOI Crossref
Whole genome case-control study of central nervous system toxicity due to antimicrobial drugs.
Ås J, Bertulyte I, Norgren N, ..., Wadelius M, Hallberg P
PLoS ONE 19 (2) e0299075 [2024-02-29; online 2024-02-29]
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The clinical spectrum of ataxia telangiectasia in a cohort in Sweden.
Lindahl H, Svensson E, Danielsson A, ..., Tesi B, Paucar M
Heliyon 10 (4) e26073 [2024-02-29; online 2024-02-15]
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Population genomic analyses reveal that salinity and geographic isolation drive diversification in a free-living protist.
Rengefors K, Annenkova N, Wallenius J, ..., Kremp A, Ahrén D
Sci Rep 14 (1) 4986 [2024-02-29; online 2024-02-29]
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New insights into complex formation by SARS-CoV-2 nsp10 and nsp14.
Sele C, Krupinska E, Andersson Rasmussen A, ..., Fisher SZ, Knecht W
Nucleosides Nucleotides Nucleic Acids 43 (8) 798-812 [2024-02-29; online 2024-02-29]
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Genetic and molecular architecture of complex traits.
Lappalainen T, Li YI, Ramachandran S, Gusev A
Cell 187 (5) 1059-1075 [2024-02-29; online 2024-03-02]
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From genomic threat assessment to conservation action.
van der Valk T, Dalèn L
Cell 187 (5) 1038-1041 [2024-02-29; online 2024-03-02]
DDLS Fellow Tom van der Valk
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scCircle-seq unveils the diversity and complexity of extrachromosomal circular DNAs in single cells.
Chen JP, Diekmann C, Wu H, ..., Bienko M, Crosetto N
Nat Commun 15 (1) 1768 [2024-02-27; online 2024-02-27]
Magda Bienko SciLifeLab Fellow
PubMed DOI Crossref
Tumor Predisposing Post-Zygotic Chromosomal Alterations in Bladder Cancer-Insights from Histologically Normal Urothelium.
Stańkowska W, Sarkisyan D, Bruhn-Olszewska B, ..., Filipowicz N, Dumanski JP
Cancers (Basel) 16 (5) - [2024-02-27; online 2024-02-27]
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Risk factors for clonal hematopoiesis of indeterminate potential in people with HIV: a report from the REPRIEVE trial.
Bhattacharya R, Uddin MM, Patel AP, ..., Grinspoon SK, Natarajan P
Blood Adv 8 (4) 959-967 [2024-02-27; online 2024-01-10]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
Predictive biomarkers of rapidly developing insulin deficiency in children with type 1 diabetes.
Lundkvist P, Grönberg A, Carlsson PO, Ludvigsson J, Espes D
BMJ Open Diabetes Res Care 12 (1) - [2024-02-27; online 2024-02-27]
Daniel Espes SciLifeLab Fellow
PubMed DOI Crossref
Equine enteroid-derived monolayers recapitulate key features of parasitic intestinal nematode infection.
Hellman S, Martin F, Tydén E, ..., Svedberg P, Fossum C
Vet Res 55 (1) 25 [2024-02-27; online 2024-02-27]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Decoding of the surfaceome and endocytome in primary glioblastoma cells identifies potential target antigens in the hypoxic tumor niche.
de Oliveira KG, Bång-Rudenstam A, Beyer S, ..., Welinder C, Belting M
Acta Neuropathol Commun 12 (1) 35 [2024-02-27; online 2024-02-27]
DOI Crossref
The energy metabolism of Cupriavidus necator in different trophic conditions
Jahn M, Crang N, Gynnå AH, ..., Charpentier E, Hudson EP
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Paul Hudson SciLifeLab Fellow
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Intestinal stroma guides monocyte differentiation to macrophages through GM-CSF.
Kvedaraite E, Lourda M, Mouratidou N, ..., Henter JI, Svensson M
Nat Commun 15 (1) 1752 [2024-02-26; online 2024-02-26]
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Insights into Drug Cardiotoxicity from Biological and Chemical Data: The First Public Classifiers for FDA Drug-Induced Cardiotoxicity Rank.
Seal S, Spjuth O, Hosseini-Gerami L, ..., Bender A, Carpenter AE
J Chem Inf Model 64 (4) 1172-1186 [2024-02-26; online 2024-02-01]
PubMed DOI Crossref
Computational analysis of human medium-chain dehydrogenases/reductases revealing substrate- and coenzyme-binding characteristics.
Östberg LJ, Höög JO, Persson B
Chem. Biol. Interact. 390 (-) 110876 [2024-02-25; online 2024-01-22]
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Mechanism of phage sensing and abortion by toxin-antitoxin-chaperone systems
Mets T, Kurata T, Ernits K, ..., Atkinson GC, Hauryliuk V
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MALT1 inhibition suppresses antigen-specific T cell responses.
Kerzeli IK, Nasi A, Fletcher E, ..., Öberg F, Mangsbo SM
Cell Immunol 397-398 (-) 104814 [2024-02-24; online 2024-02-24]
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No link between type I interferon autoantibody positivity and adverse reactions to COVID-19 vaccines.
Yalcinkaya A, Cavalli M, Cederholm A, ..., Wadelius M, Landegren N
NPJ Vaccines 9 (1) 42 [2024-02-22; online 2024-02-22]
PubMed DOI Crossref
CAGI, the Critical Assessment of Genome Interpretation, establishes progress and prospects for computational genetic variant interpretation methods.
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Genome Biol. 25 (1) 53 [2024-02-22; online 2024-02-22]
Abhishek Niroula DDLS Fellow
PubMed DOI Crossref
'It wasn't what I was suited for': regretful mothers negotiating their reproductive decision and mother role.
Bodin M
Med Humanit 50 (1) 70-76 [2024-02-22; online 2024-02-22]
PubMed DOI Crossref
Spatial Neurolipidomics at the Single Amyloid-β Plaque Level in Postmortem Human Alzheimer's Disease Brain.
Michno W, Bowman A, Jha D, ..., Heeren RMA, Hanrieder J
ACS Chem Neurosci 15 (4) 877-888 [2024-02-21; online 2024-02-01]
SciLifeLab Fellow Wojciech Michno
PubMed DOI Crossref
MIGRENE: The Toolbox for Microbial and Individualized GEMs, Reactobiome and Community Network Modelling.
Bidkhori G, Shoaie S
Metabolites 14 (3) - [2024-02-21; online 2024-02-21]
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Inhibition of Insulin-Regulated Aminopeptidase by Imidazo [1,5-α]pyridines-Synthesis and Evaluation.
Engen K, Lundbäck T, Yadav A, ..., Hallberg M, Larhed M
Int J Mol Sci 25 (5) - [2024-02-21; online 2024-02-21]
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Clonally heritable gene expression imparts a layer of diversity within cell types.
Mold JE, Weissman MH, Ratz M, ..., Michaëlsson J, Frisén J
Cell Syst 15 (2) 149-165.e10 [2024-02-21; online 2024-02-09]
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Applying a modified systematic review and integrated assessment framework (SYRINA) - a case study on triphenyl phosphate.
Bui TT, Aasa J, Abass K, ..., Yost E, Rudén C
Environ Sci Process Impacts 26 (2) 380-399 [2024-02-21; online 2024-02-21]
Oskar Karlsson SciLifeLab Fellow
PubMed DOI Crossref
Stochastic and deterministic assembly processes of microbial communities in relation to natural attenuation of black stains in Lascaux Cave.
Bontemps Z, Moënne-Loccoz Y, Hugoni M
mSystems 9 (2) e0123323 [2024-02-20; online 2024-01-30]
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SAG1.3-derived Frizzled-targeting negative allosteric modulators
Schulte G, Grätz L, Turku A, ..., Löber S, Gmeiner P
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Novel ancestry-specific primary open-angle glaucoma loci and shared biology with vascular mechanisms and cell proliferation.
Lo Faro V, Bhattacharya A, Zhou W, ..., Cox NJ, Hirbo J
Cell Rep Med 5 (2) 101430 [2024-02-20; online 2024-02-22]
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Exposure assessment suggests some cytotoxic Bacillus cereus group genotypes can grow over 3 logs in HTST milk throughout the shelf life at temperature abuse conditions
Su J, Chandross-Cohen T, Qian C, ..., Wiedmann M, Kovac J
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DDLS Fellow Laura Carroll
DOI Crossref
Exploring the interplay between antiretroviral therapy and the gut-oral microbiome axis in people living with HIV
Narayanan A, Kieri O, Vesterbacka J, ..., Ray S, Nowak P
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Delineating functional and molecular impact of ex vivo sample handling in precision medicine.
Struyf N, Österroos A, Vesterlund M, ..., Seashore-Ludlow B, Erkers T
NPJ Precis Oncol 8 (1) 38 [2024-02-19; online 2024-02-19]
PubMed DOI Crossref
Targeting autophagy as a therapeutic strategy in pediatric acute lymphoblastic leukemia.
Bwanika HC, Leo IR, Struyf N, ..., Jafari R, Pokrovskaja Tamm K
Sci Rep 14 (1) 4000 [2024-02-18; online 2024-02-18]
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Limited parallelism in genetic adaptation to brackish water bodies in European sprat and Atlantic herring
Pettersson ME, Quintela M, Besnier F, ..., Glover KA, Andersson L
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PubMed DOI Crossref
Targeting OGG1 and PARG radiosensitises head and neck cancer cells to high-LET protons through complex DNA damage persistence.
Fabbrizi MR, Nickson CM, Hughes JR, ..., Helleday T, Parsons JL
Cell Death Dis 15 (2) 150 [2024-02-17; online 2024-02-17]
PubMed DOI Crossref
Toward ovarian cancer screening with protein biomarkers using dried, self-sampled cervico-vaginal fluid.
Hedlund Lindberg J, Widgren A, Ivansson E, ..., Bergquist J, Enroth S
iScience 27 (2) 109001 [2024-02-16; online 2024-01-24]
PubMed DOI Crossref
Targeting the Main Protease (Mpro, nsp5) by Growth of Fragment Scaffolds Exploiting Structure-Based Methodologies.
Altincekic N, Jores N, Löhr F, ..., Sreeramulu S, Schwalbe H
ACS chemical biology 19 (2) 563-574 [2024-02-16; online 2024-01-17]
PubMed DOI Crossref
Preclinical evaluation of new GRPR-antagonists with improved metabolic stability for radiotheranostic use in oncology.
Kanellopoulos P, Mattsson A, Abouzayed A, ..., Maina T, Orlova A
EJNMMI Radiopharm Chem 9 (1) 13 [2024-02-16; online 2024-02-16]
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Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel.
Zhang SM, Paulin CBJ, Shu H, ..., Helleday T, Rudd SG
iScience 27 (2) 108907 [2024-02-16; online 2024-01-13]
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Community stability increases the predictability of microeukaryote community coalescence outcomes
Vass M, Székely A, Carlsson-Graner U, Wikner J, Andersson A
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PubMed DOI Crossref
A regulatory element associated to NAFLD in the promoter of DIO1 controls LDL-C, HDL-C and triglycerides in hepatic cells.
Castillejo-López C, Bárcenas-Walls JR, Cavalli M, Larsson A, Wadelius C
Lipids Health Dis 23 (1) 48 [2024-02-16; online 2024-02-16]
PubMed DOI Crossref
RhoB expression associated with chemotherapy response and prognosis in colorectal cancer.
Kopsida M, Liu N, Kotti A, ..., Pathak S, Sun XF
Cancer Cell Int 24 (1) 75 [2024-02-15; online 2024-02-15]
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Prevalent and persistent new-onset autoantibodies in mild to severe COVID-19
Jernbom Falk A, Skoglund L, Pin E, ..., Månberg A, Nilsson P
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Gel-Assisted Proteome Position Integral Shift (GAPPIS) Assay Returns Molecular Weight to Shotgun Proteomics and Identifies Novel Caspase 3 Substrates
Meng Z, Saei AA, Zhang X, ..., Gaetani M, Zubarev RA
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Chp1 is a dedicated chaperone at the ribosome that safeguards eEF1A biogenesis.
Minoia M, Quintana-Cordero J, Jetzinger K, ..., Kramer G, Andréasson C
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Breaking Barriers: pCF10 Type 4 Secretion System relies on a self-regulating muramidase to modulate the cell wall
Sun WS, Torrens G, Beek Jt, Cava F, Berntsson RPA
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A human stomach cell type transcriptome atlas.
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The N-terminal helix of MarA as a key element in the mechanism of DNA binding
Corbella M, Moreira C, Bello-Madruga R, ..., Blair JMA, Sancho-Vaello E
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Targeting MYC induces lipid droplet accumulation by upregulation of HILPDA in clear cell renal cell carcinoma.
Sainero-Alcolado L, Garde-Lapido E, Snaebjörnsson MT, ..., Schulze A, Arsenian-Henriksson M
Proc. Natl. Acad. Sci. U.S.A. 121 (7) e2310479121 [2024-02-13; online 2024-02-09]
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PubMed DOI Crossref
Most axonal mitochondria in cortical pyramidal neurons lack mitochondrial DNA and consume ATP.
Hirabayashi Y, Lewis TL, Du Y, ..., Testa I, Polleux F
bioRxiv - (-) - [2024-02-13; online 2024-02-13]
Ilaria Testa SciLifeLab Fellow
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Do light eaters live shorter lives? The case of ultralight Caenorhabditis elegans
Zhang X, Gharibi H, Beusch CM, ..., Gaetani M, Zubarev RA
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CSF protein ratios with enhanced potential to reflect Alzheimer's disease pathology and neurodegeneration.
Mravinacová S, Alanko V, Bergström S, ..., Matton A, Månberg A
Mol Neurodegener 19 (1) 15 [2024-02-13; online 2024-02-13]
PubMed DOI Crossref
A distinctive family of L,D-transpeptidases catalyzing L-Ala-mDAP crosslinks in Alpha- and Betaproteobacteria.
Espaillat A, Alvarez L, Torrens G, ..., Berntsson RP, Cava F
Nat Commun 15 (1) 1343 [2024-02-13; online 2024-02-13]
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phbuilder: A Tool for Efficiently Setting up Constant pH Molecular Dynamics Simulations in GROMACS.
Jansen A, Aho N, Groenhof G, Buslaev P, Hess B
J Chem Inf Model 64 (3) 567-574 [2024-02-12; online 2024-01-12]
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Identification of a gene network driving the attenuated response to lipopolysaccharide of monocytes from hypertensive coronary artery disease patients.
Lu C, Donners MMPC, de Baaij JBJ, ..., Goossens P, Biessen EAL
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AIRR-C IG Reference Sets: curated sets of immunoglobulin heavy and light chain germline genes.
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A high-resolution spatial map of cilia-associated proteins based on characterization of the human fallopian tube-specific proteome
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Transport mechanism of DgoT, a bacterial homolog of SLC17 organic anion transporters
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Tandem gene clusters as phylogenetic anchors reveal the hidden history of vertebrate visual opsins
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Prelude to Malignancy: A Gene Expression Signature in Normal Mammary Gland from Breast Cancer Patients Suggests Pre-tumorous Alterations and Is Associated with Adverse Outcomes
Andreou M, Jąkalski M, Duzowska K, ..., Mieczkowski J, Piotrowski A
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Covalent bicyclization of protein complexes yields durable quaternary structures.
Hutchins GH, Kiehstaller S, Poc P, ..., Hennig S, Grossmann TN
Chem 10 (2) 615-627 [2024-02-08; online 2024-02-08]
DDLS Fellow Nicholas Pearce
PubMed DOI Crossref
2D MXene electrochemical transistors.
Shakya J, Kang MA, Li J, ..., Zeglio E, Hamedi MM
Nanoscale 16 (6) 2883-2893 [2024-02-08; online 2024-02-08]
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Structural basis for the oligomerization-facilitated NLRP3 activation.
Yu X, Matico RE, Miller R, ..., Van Opdenbosch N, Sharma S
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PKSmart: An Open-Source Computational Model to Predict in vivo Pharmacokinetics of Small Molecules
Seal S, Trapotsi MA, Subramanian V, ..., Greene N, Bender A
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Immune mapping of human tuberculosis and sarcoidosis lung granulomas.
Carow B, Muliadi V, Skålén K, ..., Levin M, Rottenberg ME
Front Immunol 14 (-) 1332733 [2024-02-07; online 2024-02-07]
PubMed DOI Crossref
Author Correction: Direct RNA targeted in situ sequencing for transcriptomic profiling in tissue.
Lee H, Marco Salas S, Gyllborg D, Nilsson M
Sci Rep 14 (1) 3153 [2024-02-07; online 2024-02-07]
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A chromosome-level assembly of the seed beetle Callosobruchus maculatus genome with annotation of its repetitive elements.
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Editorial: Footprints of immune cells in the type 1 diabetic pancreas, volume II.
Christoffersson G, Fousteri G
Front Endocrinol (Lausanne) 15 (-) 1367245 [2024-02-06; online 2024-02-06]
Gustaf Christoffersson SciLifeLab Fellow
PubMed DOI Crossref
Sociodemographic characteristics and COVID-19 testing rates: spatiotemporal patterns and impact of test accessibility in Sweden.
Kennedy B, Varotsis G, Hammar U, ..., Björk J, Fall T
Eur J Public Health 34 (1) 14-21 [2024-02-05; online 2023-11-28]
PubMed DOI Crossref
Nigral transcriptomic profiles in Engrailed-1 hemizygous mouse models of Parkinson's disease reveal upregulation of oxidative phosphorylation-related genes associated with delayed dopaminergic neurodegeneration.
Belfiori LF, Dueñas Rey A, Ralbovszki DM, ..., Brolin KA, Swanberg M
Front Aging Neurosci 16 (-) 1337365 [2024-02-05; online 2024-02-05]
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N-(Heteroaryl)thiophene sulfonamides as angiotensin AT2 receptor ligands.
Wannberg J, Gising J, Henriksson M, ..., Hallberg M, Larhed M
Eur J Med Chem 265 (-) 116122 [2024-02-05; online 2024-01-03]
PubMed DOI Crossref
Single-molecule chromatin configurations link transcription factor binding to expression in human cells.
Doughty BR, Hinks MM, Schaepe JM, ..., Bintu L, Greenleaf WJ
bioRxiv - (-) - [2024-02-04; online 2024-02-04]
Emil Marklund SciLifeLab Fellow
PubMed DOI Crossref
Microfluidics and Organ-on-a-Chip for Disease Modeling and Drug Screening.
Nasiri R, Zhu Y, de Barros NR
Biosensors (Basel) 14 (2) - [2024-02-04; online 2024-02-04]
PubMed DOI Crossref
Asymmetric nucleosome PARylation at DNA breaks mediates directional nucleosome sliding by ALC1.
Bacic L, Gaullier G, Mohapatra J, ..., Sabantsev A, Deindl S
Nat Commun 15 (1) 1000 [2024-02-02; online 2024-02-02]
SciLifeLab Fellow Sebastian Deindl
PubMed DOI Crossref
Xist ribonucleoproteins promote female sex-biased autoimmunity.
Dou DR, Zhao Y, Belk JA, ..., Utz PJ, Chang HY
Cell 187 (3) 733-749.e16 [2024-02-01; online 2024-02-03]
DOI Crossref
Towards understanding of allostery in MALT1: a possible role of interdomain motions as revealed by NMR and AlphaFold
Wallerstein J, Han X, Levkovets M, ..., Agback T, Orekhov V
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PubMed DOI Crossref
Systemic and mucosal adaptive immunity to SARS-CoV-2 during the Omicron wave in patients with chronic lymphocytic leukemia.
Ingelman-Sundberg HM, Blixt L, Wullimann D, ..., Buggert M, Österborg A
Haematologica 109 (2) 646-651 [2024-02-01; online 2024-02-01]
PubMed DOI Crossref
PVT1 interacts with polycomb repressive complex 2 to suppress genomic regions with pro-apoptotic and tumour suppressor functions in multiple myeloma.
Nylund P, Garrido-Zabala B, Párraga AA, ..., Kalushkova A, Wiklund HJ
Haematologica 109 (2) 567-577 [2024-02-01; online 2024-02-01]
PubMed DOI Crossref
Noninvasive PET Detection of CD69-Positive Immune Cells Before Signs of Clinical Disease in Inflammatory Arthritis.
Puuvuori E, Shen Y, Hulsart-Billström G, ..., Wermeling F, Eriksson O
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 65 (2) 294-299 [2024-02-01; online 2024-02-01]
Olof Eriksson SciLifeLab Fellow
PubMed DOI Crossref
How do opioids control pain circuits in the brainstem during opioid-induced disorders and in chronic pain? Implications for the treatment of chronic pain.
Costa AR, Tavares I, Martins I
Pain 165 (2) 324-336 [2024-02-01; online 2023-08-11]
PubMed DOI Crossref
ClusTrast: a short read de novo transcript isoform assembler guided by clustered contigs.
Westrin KJ, Kretzschmar WW, Emanuelsson O
BMC Bioinformatics 25 (1) 54 [2024-02-01; online 2024-02-01]
PubMed DOI Crossref
A Chromosome-Level Genome Assembly and Annotation for the Clouded Apollo Butterfly (Parnassius mnemosyne): A Species of Global Conservation Concern.
Höglund J, Dias G, Olsen RA, ..., Talla V, Backström N
Genome Biol Evol 16 (2) - [2024-02-01; online 2024-02-18]
PubMed DOI Crossref
Wildlife endogenous retroviruses: colonization, consequences, and cooption.
Jern P, Greenwood AD
Trends in Genetics 40 (2) 149-159 [2024-02-00; online 2023-11-19]
PubMed DOI Crossref
Whole-genome resequencing facilitates the development of a 50K single nucleotide polymorphism genotyping array for Scots pine (Pinus sylvestris L.) and its transferability to other pine species.
Estravis Barcala M, van der Valk T, Chen Z, ..., Nilsson O, Wu HX
Plant J. 117 (3) 944-955 [2024-02-00; online 2023-11-10]
DDLS Fellow Tom van der Valk
PubMed DOI Crossref
Vaginal candida infection is associated with host molecular signatures of neutrophil activation in the adjacent ectocervical mucosa in Kenyan sex workers.
Hasselrot T, Boger MF, Kaldhusdal V, ..., Czarnewski P, Broliden K
Am. J. Reprod. Immunol. 91 (2) e13814 [2024-02-00; online 2024-02-01]
PubMed DOI Crossref
Ultrastructural insights into the microsporidian infection apparatus reveal the kinetics and morphological transitions of polar tube and cargo during host cell invasion.
Sharma H, Jespersen N, Ehrenbolger K, Carlson LA, Barandun J
PLoS Biol. 22 (2) e3002533 [2024-02-00; online 2024-02-29]
Jonas Barandun SciLifeLab Fellow
PubMed DOI Crossref
The Pseudomonas aeruginosa lectin LecB modulates intracellular reactive oxygen species production in human neutrophils.
Sanchez Klose FP, Dahlstrand Rudin A, Bergqvist L, ..., Bylund J, Venkatakrishnan V
Eur. J. Immunol. 54 (2) e2350623 [2024-02-00; online 2023-11-27]
PubMed DOI Crossref
Stress biology: Complexity and multifariousness in health and disease.
Mayer MP, Blair L, Blatch GL, ..., Wang SXY, Zininga T
Cell Stress Chaperones 29 (1) 143-157 [2024-02-00; online 2024-02-03]
Anniina Vihervaara SciLifeLab Fellow
PubMed DOI Crossref
Strategies to decrease inequalities in cancer therapeutics, care and prevention: Proceedings on a conference organized by the Pontifical Academy of Sciences and the European Academy of Cancer Sciences, Vatican City, February 23-24, 2023.
Ringborg U, von Braun J, Celis J, ..., Weiderpass E, Yang H
Mol Oncol 18 (2) 245-279 [2024-02-00; online 2024-01-22]
PubMed DOI Crossref
Sfrp1 inhibits lung fibroblast invasion during transition to injury-induced myofibroblasts.
Mayr CH, Sengupta A, Asgharpour S, ..., Burgstaller G, Schiller HB
Eur. Respir. J. 63 (2) - [2024-02-00; online 2024-02-08]
DOI Crossref
Reconstruction of genome-scale metabolic models of non-conventional yeasts: current state, challenges, and perspectives
de Almeida ELM, Kerkhoven EJ, da Silveira WB
Biotechnol Bioproc E 29 (1) 35-67 [2024-02-00; online 2024-02-13]
PubMed DOI Crossref
Predicting COVID-19 hospitalizations: The importance of healthcare hotlines, test positivity rates and vaccination coverage.
van Zoest V, Lindberg K, Varotsis G, Osei FB, Fall T
Spat Spatiotemporal Epidemiol 48 (-) 100636 [2024-02-00; online 2024-01-17]
PubMed DOI Crossref
Porcine circovirus type 2 infection promotes the SUMOylation of nucleophosmin-1 to facilitate the viral circular single-stranded DNA replication.
Du Q, Zhu L, Zhong J, ..., Tong D, Huang Y
PLoS Pathog 20 (2) e1012014 [2024-02-00; online 2024-02-23]
PubMed DOI Crossref
Plasma metabolite predictors of metabolic syndrome incidence and reversion.
Semnani-Azad Z, Toledo E, Babio N, ..., Hu FB, Guasch-Ferré M
Metabolism 151 (-) 155742 [2024-02-00; online 2023-11-24]
Clemens Wittenbecher DDLS Fellow
PubMed DOI Crossref
Pharmacokinetics and Metabolism of Melflufen, an Alkylating Peptide-Drug Conjugate, in Patients with Relapsed Refractory Multiple Myeloma.
Huledal G, Ruiz-Garcia A, Kawakatsu S, ..., Norin S, Jerling M
J Clin Pharmacol 64 (2) 240-252 [2024-02-00; online 2023-10-20]
PubMed DOI Crossref
Pathogenic DDX41 variants, possible response predictors to low-dose melphalan in hypo- and normocellular MDS and AML.
Nyquist OE, Dalgaard J, Spetalen S, ..., Baliakas P, Dybedal I
Br. J. Haematol. 204 (2) 724-729 [2024-02-00; online 2023-11-28]
DOI Crossref
On proving that an unsafe controller is not proven safe
Selvaraj Y, Krook J, Ahrendt W, Fabian M
Journal of Logical and Algebraic Methods in Programming 137 (-) 100939 [2024-02-00; online 2024-02-00]
PubMed DOI Crossref
Nutritional control of bacterial DNA replication.
Hallgren J, Jonas K
Curr Opin Microbiol 77 (-) 102403 [2024-02-00; online 2023-11-30]
Kristina Jonas SciLifeLab Fellow
PubMed DOI Crossref
Multivalent insulin receptor activation using insulin-DNA origami nanostructures.
Spratt J, Dias JM, Kolonelou C, ..., Ruas JL, Teixeira AI
Nat Nanotechnol 19 (2) 237-245 [2024-02-00; online 2023-10-09]
Antonio Lentini DDLS Fellow
PubMed DOI Crossref
Multimodal Single-Cell Sequencing of B Cells in Primary Sjögren's Syndrome.
Arvidsson G, Czarnewski P, Johansson A, ..., Nordmark G, Syvänen AC
Arthritis & rheumatology (Hoboken, N.J.) 76 (2) 255-267 [2024-02-00; online 2023-12-18]
DOI Crossref
Measuring lipid dynamics and packing with minflux microscopy
Koerfer AM, Eggeling C, Carravilla P
Biophysical Journal 123 (3) 30a [2024-02-00; online 2024-02-00]
PubMed DOI Crossref
Markers of imminent myocardial infarction.
Gustafsson S, Lampa E, Jensevik Eriksson K, ..., Fall T, Sundström J
Nat Cardiovasc Res 3 (2) 130-139 [2024-02-00; online 2024-02-12]
PubMed DOI Crossref
Ion and lipid orchestration of secondary active transport.
Drew D, Boudker O
Nature 626 (8001) 963-974 [2024-02-00; online 2024-02-28]
PubMed DOI Crossref
Intrinsic deletion at 10q23.31, including the PTEN gene locus, is aggravated upon CRISPR-Cas9-mediated genome engineering in HAP1 cells mimicking cancer profiles.
Geng K, Merino LG, Veiga RG, ..., Brinkman EK, Kutter C
Life Sci. Alliance 7 (2) - [2024-02-00; online 2023-11-20]
Claudia Kutter SciLifeLab Fellow
PubMed DOI Crossref
Inhibition of high level E2F in a RB1 proficient MYCN overexpressing chicken retinoblastoma model normalizes neoplastic behaviour.
Zhang H, Konjusha D, Rafati N, Tararuk T, Hallböök F
Cell Oncol (Dordr) 47 (1) 209-227 [2024-02-00; online 2023-08-22]
PubMed DOI Crossref
Increased Incidence and Mortality of Civilian Penetrating Traumatic Brain Injury in Sweden: A Single-Center Registry-Based Study.
Lilford RD, Hossain I, Dahlberg M, ..., Bartek J, Rostami E
World Neurosurg 182 (-) e493-e505 [2024-02-00; online 2023-11-29]
PubMed DOI Crossref
Humoral immune responses to the monovalent XBB.1.5-adapted BNT162b2 mRNA booster in Sweden.
Marking U, Bladh O, Aguilera K, ..., Sheward DJ, Thålin C
Lancet Infect Dis 24 (2) e80-e81 [2024-02-00; online 2024-01-05]
DOI Crossref
High-throughput and multi-parametric biophysical cell phenotyping with smart probes
Gurdap C, Andronico L, Cowgill J, Sezgin E
Biophysical Journal 123 (3) 449a-450a [2024-02-00; online 2024-02-00]
Erdinc Sezgin SciLifeLab Fellow
PubMed DOI Crossref
High-content screening of drug combinations of an mPGES-1 inhibitor in multicellular tumor spheroids leads to mechanistic insights into neuroblastoma chemoresistance.
Zaghmi A, Aybay E, Jiang L, ..., Seashore-Ludlow B, Larsson K
Mol Oncol 18 (2) 317-335 [2024-02-00; online 2023-08-21]
PubMed DOI Crossref
Genomic variation in montane bumblebees in Scandinavia: High levels of intraspecific diversity despite population vulnerability.
Liu Y, Olsson A, Larva T, ..., Cederberg B, Webster MT
Mol. Ecol. 33 (4) e17251 [2024-02-00; online 2023-12-19]
PubMed DOI Crossref
Evidence from Finland and Sweden on the relationship between early-life diseases and lifetime childlessness in men and women.
Liu A, Akimova ET, Ding X, ..., Mills MC, Ganna A
Nat Hum Behav 8 (2) 276-287 [2024-02-00; online 2023-12-18]
DOI Crossref
Electroporation of bacteria in microfluidic device
Volkov IL, Khaji Z, Johansson M, Tenje M
Biophysical Journal 123 (3) 436a [2024-02-00; online 2024-02-00]
PubMed DOI Crossref
Effects of exercise on whole-blood transcriptome profile in children with overweight/obesity.
Altmäe S, Plaza-Florido A, Esteban FJ, ..., Radom-Aizik S, Ortega FB
Am J Hum Biol 36 (2) e23983 [2024-02-00; online 2023-09-16]
PubMed DOI Crossref
Editorial overview: Computational neuroscience as a bridge between artificial intelligence, modeling and data.
Verzelli P, Tchumatchenko T, Kotaleski JH
Curr Opin Neurobiol 84 (-) 102835 [2024-02-00; online 2024-01-06]
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Determining protein conformational ensembles by combining machine learning and small-angle scattering
Lidbrink SE, Nandan Haloi , Howard RJ, Lindahl ER
Biophysical Journal 123 (3) 431a [2024-02-00; online 2024-02-00]
PubMed DOI Crossref
Antisecretory factor in breastmilk is associated with reduced incidence of sepsis in preterm infants.
Gustafsson A, Johansson E, Henckel E, ..., Lange S, Bohlin K
Pediatr. Res. 95 (3) 762-769 [2024-02-00; online 2023-11-24]
PubMed DOI Crossref
ATG12-ATG5-TECPR1: an alternative E3-like complex utilized during the cellular response to lysosomal membrane damage.
Corkery DP, Wu YW
Autophagy 20 (2) 443-444 [2024-02-00; online 2024-01-25]
PubMed DOI Crossref
A survey of ficolin-3 activity in Systemic Lupus Erythematosus reveals a link to hematological disease manifestations and autoantibody profile.
Lindelöf L, Rantapää-Dahlqvist S, Lundtoft C, ..., Svenungsson E, Eriksson O
J. Autoimmun. 143 (-) 103166 [2024-02-00; online 2024-01-13]
PubMed DOI Crossref
A peptidoglycan N-deacetylase specific for anhydroMurNAc chain termini in Agrobacterium tumefaciens.
Gilmore MC, Yadav AK, Espaillat A, ..., Brown PJB, Cava F
J Biol Chem 300 (2) 105611 [2024-02-00; online 2023-12-28]
PubMed DOI Crossref
A cholesterol switch controls phospholipid scrambling by G protein-coupled receptors.
Menon I, Sych T, Son Y, ..., Levitz J, Menon AK
J Biol Chem 300 (2) 105649 [2024-02-00; online 2024-01-16]
Erdinc Sezgin SciLifeLab Fellow
DOI Crossref
A Perfusable Multi‐Hydrogel Vasculature On‐Chip Engineered by 2‐Photon 3D Printing and Scaffold Molding to Improve Microfabrication Fidelity in Hydrogels
Cantoni F, Barbe L, Pohlit H, Tenje M
Adv Materials Technologies 9 (4) - [2024-02-00; online 2024-01-04]
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ESPressoscope: a small and powerful platform for in situ microscopy
Li E, Saggiomo V, Ouyang W, Prakash M, Diederich B
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DDLS Fellow Wei Ouyang
PubMed DOI Crossref
Discovery of lipid binding sites in a ligand-gated ion channel by integrating simulations and cryo-EM.
Bergh C, Rovšnik U, Howard R, Lindahl E
Elife 12 (-) - [2024-01-30; online 2024-01-30]
DOI Crossref
Discovery of lipid binding sites in a ligand-gated ion channel by integrating simulations and cryo-EM
Bergh C, Rovšnik U, Howard R, Lindahl E
Elife 12 (-) - [2024-01-30; online 2024-01-30]
PubMed DOI Crossref
A two-step activation mechanism enables mast cells to differentiate their response between extracellular and invasive enterobacterial infection.
von Beek C, Fahlgren A, Geiser P, ..., Pejler G, Sellin ME
Nat Commun 15 (1) 904 [2024-01-30; online 2024-01-30]
Mikael Sellin SciLifeLab Fellow
PubMed DOI Crossref
Interactive computational and experimental approaches improve the sensitivity of periplasmic binding protein-based nicotine biosensors for measurements in biofluids.
Haloi N, Huang S, Nichols AL, ..., Mayo SL, Lester HA
Protein Eng. Des. Sel. 37 (-) - [2024-01-29; online 2024-02-02]
PubMed DOI Crossref
AutoTransOP: translating omics signatures without orthologue requirements using deep learning.
Meimetis N, Pullen KM, Zhu DY, ..., Magliacane S, Lauffenburger DA
NPJ Syst Biol Appl 10 (1) 13 [2024-01-29; online 2024-01-29]
Avlant Nilsson DDLS Fellow
PubMed DOI Crossref
Sensitive and Specific Analyses of Colorectal Cancer Recurrence through Multiplex superRCA Mutation Detection in Blood Plasma.
Sandberg E, Nunes L, Edqvist PH, ..., Landegren U, Sjöblom T
Cancers (Basel) 16 (3) - [2024-01-27; online 2024-01-27]
PubMed DOI Crossref
Sex-Specific Associations between Prenatal Exposure to Di(2-ethylhexyl) Phthalate, Epigenetic Age Acceleration, and Susceptibility to Early Childhood Upper Respiratory Infections.
Merrill SM, Letourneau N, Giesbrecht GF, ..., Dewey D, England-Mason G
Epigenomes 8 (1) - [2024-01-26; online 2024-01-26]
DOI Crossref
SMAC mimetics overcome apoptotic resistance in ovarian cancer through MSLN-TNF alpha axis
Coelho R, Seashore-Ludlow B, Schütz S, ..., Heinzelmann-Schwarz V, Jacob F
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DOI Crossref
Resolution of ribosomal stalling by ABCF ATPases YfmR and YkpA/YbiT
Takada H, Fujiwara K, Atkinson GC, Shinobu C, Hauryliuk V
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DOI Crossref
Divergent mechanisms of steroid inhibition in the human ρ1 GABA A receptor
Fan C, Cowgill J, Howard RJ, Lindahl E
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DOI Crossref
Continental scientific drilling and microbiology: (extremely) low biomass in bedrock of central Sweden
Westmeijer G, Escudero C, Bergin C, ..., Bertilsson S, Dopson M
Biogeosciences 21 (2) 591-604 [2024-01-26; online 2024-01-26]
PubMed DOI Crossref
Comparative genomic analyses provide new insights into evolutionary history and conservation genomics of gorillas.
van der Valk T, Jensen A, Caillaud D, Guschanski K
BMC Ecol Evol 24 (1) 14 [2024-01-26; online 2024-01-26]
DDLS Fellow Tom van der Valk
PubMed DOI Crossref
Association of genetic variation in COL11A1 with adolescent idiopathic scoliosis.
Yu H, Khanshour AM, Ushiki A, ..., Ahituv N, Wise CA
Elife 12 (-) - [2024-01-26; online 2024-01-26]
DOI Crossref
Association of genetic variation in COL11A1 with adolescent idiopathic scoliosis
Yu H, Khanshour AM, Ushiki A, ..., Ahituv N, Wise CA
Elife 12 (-) - [2024-01-26; online 2024-01-26]
PubMed DOI Crossref
tRNA shape is an identity element for an archaeal pyrrolysyl-tRNA synthetase from the human gut.
Krahn N, Zhang J, Melnikov SV, ..., Puglisi J, Söll D
Nucleic Acids Res. 52 (2) 513-524 [2024-01-25; online 2023-12-15]
DOI Crossref
Unravelling the ancient fungal DNA from the Iceman’s gut
Oskolkov N, Sandionigi A, Göterström A, ..., Buzzini P, Borruso L
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DOI Crossref
High-parametric protein maps reveal the spatial organization in early-developing human lung
Sariyar S, Sountoulidis A, Hansen JN, ..., Lundberg E, Ayoglu B
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PubMed DOI Crossref
Escherichia coli CadB is capable of promiscuously transporting muropeptides and contributing to peptidoglycan recycling.
Simpson BW, Gilmore MC, McLean AB, Cava F, Trent MS
J. Bacteriol. 206 (1) e0036923 [2024-01-25; online 2024-01-03]
PubMed DOI Crossref
The potential of liquid biopsy for detection of the KIAA1549-BRAF fusion in circulating tumor DNA from children with pilocytic astrocytoma.
Krynina O, de Ståhl TD, Jylhä C, ..., Tham E, Sandvik U
Neurooncol Adv 6 (1) vdae008 [2024-01-24; online 2024-01-24]
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Personalized oral care (Precaries): an intervention study customized according to genetic cause and risk
Westerlund A, Khalifa H, Yousif R, ..., Larsson P, Strömberg N
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DDLS Fellow Laura Carroll
DOI Crossref
Neuropilin-1 controls vascular permeability through juxtacrine regulation of endothelial adherens junctions
Pal S, Su Y, Nwadozi E, Claesson-Welsh L, Richards M
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PubMed DOI Crossref
Integration of multiple flexible electrodes for real-time detection of barrier formation with spatial resolution in a gut-on-chip system.
Lucchetti M, Werr G, Johansson S, ..., Wilmes P, Tenje M
Microsyst. Nanoeng. 10 (-) 18 [2024-01-24; online 2024-01-24]
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Comparison of the performance of multiple whole-genome sequence-based tools for the identification of Bacillus cereus sensu stricto biovar Thuringiensis
Chung T, Salazar A, Harm G, ..., Carroll LM, Kovac J
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DDLS Fellow Laura Carroll
DOI Crossref
READv2: Advanced and user-friendly detection of biological relatedness in archaeogenomics
Alaçamlı E, Naidoo T, Aktürk Ş, ..., Malmström H, Günther T
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PubMed DOI Crossref
Immunomodulatory Nanoparticles for Modulating Arthritis Flares.
Johnson WT, McBride D, Kerr M, ..., Bottini N, Shah NJ
ACS Nano 18 (3) 1892-1906 [2024-01-23; online 2023-11-28]
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Engineering multivalent Fc display for FcγR blockade
Petrova E, Kiriako G, Rebetz J, ..., Semple JW, Teixeira AI
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PubMed DOI Crossref
Cancer Diagnoses After Recent Weight Loss.
Wang QL, Babic A, Rosenthal MH, ..., Yuan C, Wolpin BM
JAMA 331 (4) 318-328 [2024-01-23; online 2024-01-23]
DDLS Fellow Qiaoli Wang
PubMed DOI Crossref
A New Synthesized Dicarboxylated Oxy-Heparin Efficiently Attenuates Tumor Growth and Metastasis.
Li L, Barash U, Ilan N, ..., Vlodavsky I, Li JP
Cells 13 (3) - [2024-01-23; online 2024-01-23]
PubMed DOI Crossref
Benchmarking enrichment analysis methods with the disease pathway network.
Buzzao D, Castresana-Aguirre M, Guala D, Sonnhammer ELL
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METTL17 is an Fe-S cluster checkpoint for mitochondrial translation.
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A structurally precise mechanism links an epilepsy-associated KCNC2 potassium channel mutation to interneuron dysfunction.
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Ultralight Ultrafast Enzymes.
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Impaired spermatogenesis and associated endocrine effects of azole fungicides in peripubertal Xenopus tropicalis.
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Oskar Karlsson SciLifeLab Fellow
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Exploring different methodological approaches to unlock paleobiodiversity in peat profiles using ancient DNA.
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Experimental evaluation of a direct fitness effect of the de novo evolved mouse gene Pldi
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Apoptosis-mediated ADAM10 activation removes a mucin barrier promoting T cell efferocytosis.
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Three cases with chronic obsessive compulsive disorder report gains in wellbeing and function following rituximab treatment
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Profiling of Surface Protein Epitopes on Viral Particles by Multiplex Dual-Reporter Strategy.
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Observation of a single protein by ultrafast X-ray diffraction.
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Universal Biomaterial-on-Chip: a versatile platform for evaluating cellular responses on diverse biomaterial substrates.
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Sensitive and Specific Analyses of Colorectal Cancer Recurrence through Multiplex superRCA Mutation Detection in Blood Plasma
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Precision microbial intervention improves social behavior but not autism severity: A pilot double-blind randomized placebo-controlled trial.
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Multi-ancestry polygenic risk scores for venous thromboembolism.
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Introduction of a fatty acid chain modification to prolong circulatory half-life of a radioligand towards glucose-dependent insulinotropic polypeptide receptor.
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Viral proteins activate PARIS-mediated tRNA degradation and viral tRNAs rescue infection.
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Multilayer DNA Origami with Terminal Interfaces That Are Flat and Wide-Area.
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Erik Benson SciLifeLab Fellow
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High-Throughput DNA melt measurements enable improved models of DNA folding thermodynamics
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Emil Marklund SciLifeLab Fellow
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All SNAP25 molecules in the vesicle-plasma membrane contact zone change conformation during vesicle priming.
Zhao Y, Fang Q, Sharma S, ..., Jahn R, Lindau M
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Single-cell genomics of a bloom-forming phytoplankton species reveals population genetic structure across continents.
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Separating phases of allopolyploid evolution with resynthesized and natural Capsella bursa-pastoris.
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Separating phases of allopolyploid evolution with resynthesized and natural Capsella bursa-pastoris
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Investigating chromosomal instability in long-term survivors with glioblastoma and grade 4 astrocytoma.
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Geographic population structure and distinct intra-population dynamics of globally abundant freshwater bacteria.
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Sarahi Garcia SciLifeLab Fellow
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GDF15 Protects Insulin-Producing Beta Cells against Pro-Inflammatory Cytokines and Metabolic Stress via Increased Deamination of Intracellular Adenosine.
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A cholesterol switch controls phospholipid scrambling by G protein-coupled receptors.
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Erdinc Sezgin SciLifeLab Fellow
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Reviewer #3 (Public Review): Deep learning insights into the architecture of the mammalian egg-sperm fusion synapse
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Longevity interventions modulate mechanotransduction and extracellular matrix homeostasis in C. elegans.
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Andrea Fossati DDLS Fellow
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Interaction molecular QTL mapping discovers cellular and environmental modifiers of genetic regulatory effects.
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Exonic trinucleotide repeat expansions in ZFHX3 cause spinocerebellar ataxia type 4: A poly-glycine disease.
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Magda Bienko SciLifeLab Fellow
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Mutation of the cyclooxygenase 2 gene promoter and anastomotic leakage in colorectal cancer patients: retrospective cohort study.
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Bridging Generalization Gaps in High Content Imaging Through Online Self-Supervised Domain Adaptation
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Are Natural Domain Foundation Models Useful for Medical Image Classification?
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A Conserved Ribosomal Protein Has Entirely Dissimilar Structures in Different Organisms.
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Mol. Biol. Evol. 41 (1) - [2024-01-03; online 2023-11-21]
Jonas Barandun SciLifeLab Fellow
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Tissue-specific RNA Polymerase II promoter-proximal pause release and burst kinetics in a Drosophila embryonic patterning network.
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The Surface of Ionic Liquids in Water: From an Ionic Tug of War to a Quasi-Ordered Two-Dimensional Layer.
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Targeting MTHFD2 to Exploit Cancer-Specific Metabolism and the DNA Damage Response.
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Pathway analysis through mutual information.
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M-Ionic: prediction of metal-ion-binding sites from sequence using residue embeddings.
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Functional annotation of a divergent genome using sequence and structure-based similarity.
Svedberg D, Winiger RR, Berg A, ..., Vossbrinck CR, Barandun J
BMC Genomics 25 (1) 6 [2024-01-02; online 2024-01-02]
Jonas Barandun SciLifeLab Fellow
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Clonal Hematopoiesis Risk Score and All-Cause and Cardiovascular Mortality in Older Adults.
Saadatagah S, Uddin MM, Weeks LD, ..., Natarajan P, Ballantyne CM
JAMA Netw Open 7 (1) e2351927 [2024-01-02; online 2024-01-02]
Abhishek Niroula DDLS Fellow
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Characterization and biological applications of gonadal extract of Paracentrotus lividus collected along the Mediterranean coast of Alexandria, Egypt.
Nagy NS, Essawy AE, Al-Sherif SS, ..., Alsawy ES, Helal M
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A comprehensive dataset on spatiotemporal variation of microbial plankton communities in the Baltic Sea.
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Specifying cellular context of transcription factor regulons for exploring context-specific gene regulation programs.
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Global Transcriptome Analysis Reveals Distinct Phases of the Endothelial Response to TNF.
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Effect of mode of delivery of patient reported outcomes in patients with breast disease: a randomised controlled trial.
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Discovery and biological evaluation of novel dual PTP1B and ACP1 inhibitors for the treatment of insulin resistance.
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Detection of Antibodies Against the African Parasite Trypanosoma brucei Using Synthetic glycosylphosphatidylinositol oligosaccharide fragments
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Beyond Basic Characterization and Omics: Immunomodulatory Roles of Platelet-Derived Extracellular Vesicles Unveiled by Functional Testing
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Use and perceived utility of [18 F]FDG PET/CT in neuroendocrine neoplasms: A consensus report from the European Neuroendocrine Tumor Society (ENETS) Advisory Board Meeting 2022.
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Adil Mardinoglu SciLifeLab Fellow
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Treatment with a tissue-selective oestrogen complex does not affect disease pathology but reduces pre-BI cells in lupus-prone mice.
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Transfer of cetirizine/levocetirizine into human breast milk and estimation of drug exposure to infants through breastfeeding: A human lactation study from the ConcePTION project.
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The role of the 5' sensing function of ribonuclease E in cyanobacteria.
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RNA Biol 21 (1) 1-18 [2024-01-00; online 2024-03-12]
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The genetic legacy of the expansion of Bantu-speaking peoples in Africa.
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Nature 625 (7995) 540-547 [2024-01-00; online 2023-11-29]
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The cascade of care for patients with chronic hepatitis delta in Southern Stockholm, Sweden for the past 30 years.
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Substance P, NPY, CCK and their receptors in five brain regions in major depressive disorder with transcriptomic analysis of locus coeruleus neurons.
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Pulmonary function and atherosclerosis in the general population: causal associations and clinical implications.
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One Year Weekly Size‐Resolved Air Sampling of SARS‐CoV‐2 in Hospital Corridors and Relations to the Indoor Environment
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Indoor Air 2024 (1) - [2024-01-00; online 2024-03-27]
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Novel PNKP mutations associated with reduced DNA single-strand break repair and severe microcephaly, seizures, and developmental delay.
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Mol Genet Genomic Med 12 (1) e2295 [2024-01-00; online 2023-11-02]
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Non-invasive imaging of sympathetic innervation of the pancreas in individuals with type 2 diabetes.
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Diabetologia 67 (1) 199-208 [2024-01-00; online 2023-11-07]
Daniel Espes Gustaf Christoffersson Olof Eriksson SciLifeLab Fellow
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New chemical and microbial perspectives on vitamin B1 and vitamer dynamics of a coastal system.
Bittner MJ, Bannon CC, Rowland E, ..., Paerl RW, Riemann L
ISME Commun 4 (1) ycad016 [2024-01-00; online 2024-01-10]
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Multiplexed experimental strategies for fragment library screening against challenging drug targets using SPR biosensors.
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SLAS Discov 29 (1) 40-51 [2024-01-00; online 2023-09-14]
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Molecular profiling of high-level athlete skeletal muscle after acute endurance or resistance exercise - A systems biology approach.
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Mol Metab 79 (-) 101857 [2024-01-00; online 2023-12-21]
Adil Mardinoglu DDLS Fellow Muhammad Arif SciLifeLab Fellow
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JDLL: a library to run deep learning models on Java bioimage informatics platforms.
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Nat. Methods 21 (1) 7-8 [2024-01-00; online 2024-01-09]
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Enrichment of different taxa of the enigmatic candidate phyla radiation bacteria using a novel picolitre droplet technique.
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ISME Commun 4 (1) ycae080 [2024-01-00; online 2024-06-21]
Sarahi Garcia SciLifeLab Fellow
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Electroencephalography findings in menstrually-related mood disorders: A critical review.
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Front Neuroendocrinol 72 (-) 101120 [2024-01-00; online 2024-01-02]
Erika Comasco SciLifeLab Fellow
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Distinct molecular targets of ProEGCG from EGCG and superior inhibition of angiogenesis signaling pathways for treatment of endometriosis.
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Clinical and genetic analyses of a Swedish patient series diagnosed with ataxia.
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Calcium-gated potassium channel blockade via membrane-facing fenestrations.
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Aberrant microbiomes are associated with increased antibiotic resistance gene load in hybrid mice.
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ISME Commun 4 (1) ycae053 [2024-01-00; online 2024-04-15]
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Transfer Learning-Assisted Inverse Modeling in Nanophotonics Based on Mixture Density Networks
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IEEE Access 12 (-) 55218-55224 [2024-00-00; online 2024-00-00]
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Toward safer and more sustainable by design biocatalytic amide-bond coupling
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Specificity and Dynamics of H2o2 Detoxification by the Cytosolic Redox Regulatory Network as Revealed by in Vitro Reconstitution
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Spatial Transcriptomics Reveals an Unexpected Impact of Tau and Tau Pathology on the Expression of Transthyretin
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Semi-supervised Learning While Controlling the FDR with an Application to Tandem Mass Spectrometry Analysis
Freestone J, Käll L, Noble WS, Keich U
- - (-) 448-453 [2024-00-00; online 2024-05-17]
DOI Crossref
Screening of Biological Samples with HRMS to Evaluate the External Human Chemical Exposome
Sunyer-Caldú A, Marquès M, Gil-Solsona R, Gago-Ferrero P
- - (-) 143-175 [2024-00-00; online 2024-06-15]
DOI Crossref
Pulp Wastewater Treatment Using Anaerobic Moving Bed Biofilm Reactors: A Case-Study
Bard S, Jacobsson S, Pizzul L, ..., Morgan-Sagastume F, Delgado LF
- - (-) 234-239 [2024-00-00; online 2024-06-18]
DOI Crossref
Privacy Protection in MRI Scans Using 3D Masked Autoencoders
Van der Goten LA, Smith K, the Alzheimer’s Disease Neuroimagin f
- - (-) 583-592 [2024-00-00; online 2024-10-03]
DOI Crossref
Optical Fiber-Based Module for Selection and Picking of Cells and Cell Clusters
Harish AV, Varela J, Gibbon T, ..., Russom A, Laurell F
EPJ Web Conf. 309 (-) 12007 [2024-00-00; online 2024-10-31]
DOI Crossref
Optical Fiber Based Cell Picking Module for Identification and Isolation of Single Cells or Clusters
Harish AV, Varela JC, Maniewski P, ..., Russom A, Laurell F
- - (-) ATh1B.2 [2024-00-00; online 2024-00-00]
DOI Crossref
Multi-Tissue Network Analysis Reveals the Effect of JNK Inhibition on Dietary Sucrose-Induced Metabolic Dysfunction in Rats
Yang H, Zhang C, Kim W, ..., Turkez H, Mardinoglu A
- - (-) - [2024-00-00; online 2024-00-00]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Integrative Proteo-Transcriptomic Characterization of Advanced Fibrosis in Chronic Liver Disease Across Etiologies
Yang H, Atak D, Yuan M, ..., Mardinoglu A, Zeybel M
- - (-) - [2024-00-00; online 2024-00-00]
Adil Mardinoglu SciLifeLab Fellow
DOI Crossref
Herbs, Spices and Alcoholic Beverages May Elicit Cephalic Phase Responses, Involving Innate Reflexes, which Modulate Digestive Activity
MK M
JJGH 10 (08) 01-08 [2024-00-00; online 2024-00-00]
DOI Crossref
BehavioUral profiling predicts vulnerability and resilience to stress exposure
Marsili F, Bon GM, Viglione A, ..., Poggini S, Branchi I
Neuroscience Applied 3 (-) 104016 [2024-00-00; online 2024-00-00]
DOI Crossref
Adaptive RESOLFT microscopy
Lin R, Testa I
- - (-) OW1F.1 [2024-00-00; online 2024-00-00]
Ilaria Testa SciLifeLab Fellow
SciLifeLab Data Centre
Publications 9.5.1