Publications 2014

581 publications

The kidney transcriptome and proteome defined by transcriptomics and antibody-based profiling.
Habuka M, Fagerberg L, Hallström BM, ..., Uhlén M, Odeberg J
PLoS ONE 9 (12) e116125 [2014-12-31; online 2014-12-31]
Affiliated researcher
Genomic, proteomic, morphological, and phylogenetic analyses of vB_EcoP_SU10, a podoviridae phage with C3 morphology.
Khan Mirzaei M, Mirzaei MK, Eriksson H, ..., Haggård-Ljungquist E, Nilsson AS
PLoS ONE 9 (12) e116294 [2014-12-31; online 2014-12-31]
Affiliated researcher
Prehistoric genomes reveal the genetic foundation and cost of horse domestication.
Schubert M, Jónsson H, Chang D, ..., Shapiro B, Orlando L
Proc. Natl. Acad. Sci. U.S.A. 111 (52) E5661-E5669 [2014-12-30; online 2014-12-15]
Affiliated researcher
The human pancreas proteome defined by transcriptomics and antibody-based profiling.
Danielsson A, Pontén F, Fagerberg L, ..., Korsgren O, Lindskog C
PLoS ONE 9 (12) e115421 [2014-12-29; online 2014-12-29]
Affiliated researcher
The transcriptomic and proteomic landscapes of bone marrow and secondary lymphoid tissues.
Andersson S, Nilsson K, Fagerberg L, ..., Uhlen M, Asplund A
PLoS ONE 9 (12) e115911 [2014-12-26; online 2014-12-26]
Affiliated researcher
Mechanical stress downregulates MHC class I expression on human cancer cell membrane.
La Rocca R, Tallerico R, Talib Hassan A, ..., Di Fabrizio E, Carbone E
PLoS ONE 9 (12) e111758 [2014-12-26; online 2014-12-26]
Affiliated researcher
Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence.
Genovese G, Kähler AK, Handsaker RE, ..., Hultman CM, McCarroll SA
N. Engl. J. Med. 371 (26) 2477-2487 [2014-12-25; online 2014-11-26]
Affiliated researcher
Therapeutic vaccination against fibronectin ED-A attenuates progression of metastatic breast cancer.
Femel J, Huijbers EJ, Saupe F, ..., Hellman L, Olsson AK
Oncotarget 5 (23) 12418-12427 [2014-12-15; online 2014-11-02]
Affiliated researcher
The scaffold protein WRAP53β orchestrates the ubiquitin response critical for DNA double-strand break repair.
Henriksson S, Rassoolzadeh H, Hedström E, ..., Helleday T, Farnebo M
Genes Dev. 28 (24) 2726-2738 [2014-12-15; online 2014-12-17]
Affiliated researcher
Rapid pulsed whole genome sequencing for comprehensive acute diagnostics of inborn errors of metabolism.
Stranneheim H, Engvall M, Naess K, ..., von Döbeln U, Wedell A
BMC Genomics 15 (-) 1090 [2014-12-11; online 2014-12-11]
Affiliated researcher
Diagnostics of primary immunodeficiency diseases: a sequencing capture approach.
Moens LN, Falk-Sörqvist E, Asplund AC, ..., Smith CI, Nilsson M
PLoS ONE 9 (12) e114901 [2014-12-11; online 2014-12-11]
Affiliated researcher
Sensitive detection of aggregated prion protein via proximity ligation.
Hammond M, Wik L, Deslys JP, ..., Landegren U, Kamali-Moghaddam M
Prion 8 (3) 261-265 [2014-12-09; online 2014-12-09]
Affiliated researcher
TGFβ receptor 1: an immune susceptibility gene in HPV-associated cancer.
Levovitz C, Chen D, Ivansson E, ..., Boffetta P, Sikora AG
Cancer Res. 74 (23) 6833-6844 [2014-12-01; online 2014-10-01]
Affiliated researcher
Toxicogenomics directory of chemically exposed human hepatocytes
Grinberg M, Stöber RM, Edlund K, ..., Rahnenführer J, Hengstler JG
Arch Toxicol 88 (12) 2261-2287 [2014-12-00; online 2014-11-16]
Adil Mardinoglu Affiliated researcher SciLifeLab Fellow
The lung-specific proteome defined by integration of transcriptomics and antibody-based profiling.
Lindskog C, Fagerberg L, Hallström B, ..., Pontén F, Micke P
FASEB J. 28 (12) 5184-5196 [2014-12-00; online 2014-08-28]
Affiliated researcher
Large-scale metabolomic profiling identifies novel biomarkers for incident coronary heart disease.
Ganna A, Salihovic S, Sundström J, ..., Fall T, Ingelsson E
PLoS Genet 10 (12) e1004801 [2014-12-00; online 2014-12-11]
Affiliated researcher
Inhibition of Insulin-Regulated Aminopeptidase (IRAP) by Arylsulfonamides.
Borhade SR, Rosenström U, Sävmarker J, ..., Larhed M, Hallberg M
ChemistryOpen 3 (6) 256-263 [2014-12-00; online 2014-11-21]
Affiliated researcher
Efficient application of next-generation sequencing for the diagnosis of rare genetic syndromes.
Madrigal I, Alvarez-Mora MI, Karlberg O, ..., Syvänen AC, Milà M
J. Clin. Pathol. 67 (12) 1099-1103 [2014-12-00; online 2014-09-30]
Affiliated researcher
Classification aided domain reduction for high dimensional optimization
Singh P, Ferranti F, Deschrijver D, Couckuyt I, Dhaene T
- - (-) - [2014-12-00; online 2014-12-00]
Prashant Singh SciLifeLab Fellow
Community-driven development for computational biology at Sprints, Hackathons and Codefests.
Möller S, Afgan E, Banck M, ..., Katayama T, Chapman BA
BMC Bioinformatics 15 Suppl 14 (-) S7 [2014-11-27; online 2014-11-27]
Affiliated researcher
1p36 deletion is a marker for tumour dissemination in microsatellite stable stage II-III colon cancer.
Mayrhofer M, Kultima HG, Birgisson H, ..., Glimelius B, Isaksson A
BMC Cancer 14 (-) 872 [2014-11-24; online 2014-11-24]
Affiliated researcher
Microwave Heated Flow Synthesis of Spiro-oxindole Dihydroquinazolinone Based IRAP Inhibitors
Engen K, Sävmarker J, Rosenström U, ..., Jenmalm-Jensen A, Larhed M
Org. Process Res. Dev. 18 (11) 1582-1588 [2014-11-21; online 2014-10-16]
Affiliated researcher
Constitutive activation of the ERK pathway in melanoma and skin melanocytes in Grey horses.
Jiang L, Campagne C, Sundström E, ..., Andersson L, Golovko A
BMC Cancer 14 (-) 857 [2014-11-21; online 2014-11-21]
Affiliated researcher
Single-cell transcriptomics for microbial eukaryotes.
Kolisko M, Boscaro V, Burki F, Lynn DH, Keeling PJ
Curr. Biol. 24 (22) R1081-R1082 [2014-11-17; online 2014-11-17]
Fabien Burki SciLifeLab Fellow
Structure of the large ribosomal subunit from human mitochondria
Brown A, Amunts A, Bai Xc, ..., Scheres SHW, Ramakrishnan V
Science 346 (6210) 718-722 [2014-11-07; online 2014-10-02]
Alexey Amunts SciLifeLab Fellow
Analysis of autoantibody profiles in osteoarthritis using comprehensive protein array concepts.
Henjes F, Lourido L, Ruiz-Romero C, ..., Nilsson P, Fuentes M
J. Proteome Res. 13 (11) 5218-5229 [2014-11-07; online 2014-10-09]
Affiliated researcher
Affinity proteomic profiling of plasma, cerebrospinal fluid, and brain tissue within multiple sclerosis.
Byström S, Ayoglu B, Häggmark A, ..., Nilsson P, Schwenk JM
J. Proteome Res. 13 (11) 4607-4619 [2014-11-07; online 2014-10-01]
Affiliated researcher
Detection of rotavirus using padlock probes and rolling circle amplification.
Mezger A, Öhrmalm C, Herthnek D, Blomberg J, Nilsson M
PLoS ONE 9 (11) e111874 [2014-11-04; online 2014-11-04]
Affiliated researcher
Gallium-68-labeled affibody molecule for PET imaging of PDGFRβ expression in vivo.
Strand J, Varasteh Z, Eriksson O, ..., Orlova A, Tolmachev V
Mol. Pharm. 11 (11) 3957-3964 [2014-11-03; online 2014-07-23]
Olof Eriksson SciLifeLab Fellow
Study of protein and RNA in dendritic spines using multi-isotope imaging mass spectrometry (MIMS).
Brismar H, Aperia A, Westin L, ..., Poczatek C, Lechene C
Surf Interface Anal 46 (Suppl 1) 158-160 [2014-11-01; online 2015-09-18]
Affiliated researcher
Systemic lupus erythematosus prevalence in Sweden in 2010: what do national registers say?
Simard JF, Sjöwall C, Rönnblom L, Jönsen A, Svenungsson E
Arthritis Care Res (Hoboken) 66 (11) 1710-1717 [2014-11-00; online 2014-04-24]
Affiliated researcher
Silenced B-cell receptor response to autoantigen in a poor-prognostic subset of chronic lymphocytic leukemia.
Bergh AC, Evaldsson C, Pedersen LB, ..., Rosenquist R, Rosén A
Haematologica 99 (11) 1722-1730 [2014-11-00; online 2014-08-01]
Affiliated researcher
Polymeric Smart Coating Strategy for Titanium Implants
Berts I, Ossipov D, Fragneto G, Frisk A, Rennie AR
Adv. Eng. Mater. 16 (11) 1340-1350 [2014-11-00; online 2014-04-01]
Affiliated researcher
Parallel barcoding of antibodies for DNA-assisted proteomics.
Dezfouli M, Vickovic S, Iglesias MJ, Schwenk JM, Ahmadian A
Proteomics 14 (21-22) 2432-2436 [2014-11-00; online 2014-09-30]
Affiliated researcher Sanja Vickovic SciLifeLab Fellow
Influence of persistent organic pollutants on oxidative stress in population-based samples.
Kumar J, Monica Lind P, Salihovic S, ..., Lind L, Ingelsson E
Chemosphere 114 (-) 303-309 [2014-11-00; online 2014-06-02]
Affiliated researcher
Evolution reveals a glutathione-dependent mechanism of 3-hydroxypropionic acid tolerance.
Kildegaard KR, Hallström BM, Blicher TH, ..., Nielsen J, Borodina I
Metab. Eng. 26 (-) 57-66 [2014-11-00; online 2014-09-28]
Affiliated researcher
Defining the role of common variation in the genomic and biological architecture of adult human height.
Wood AR, Esko T, Yang J, ..., Hirschhorn JN, Frayling TM
Nat. Genet. 46 (11) 1173-1186 [2014-11-00; online 2014-10-05]
Affiliated researcher
Challenges in computational studies of enzyme structure, function and dynamics.
Carvalho AT, Barrozo A, Doron D, ..., Major DT, Kamerlin SC
J. Mol. Graph. Model. 54 (-) 62-79 [2014-11-00; online 2014-09-28]
Affiliated researcher
Binning metagenomic contigs by coverage and composition.
Alneberg J, Bjarnason BS, de Bruijn I, ..., Andersson AF, Quince C
Nat. Methods 11 (11) 1144-1146 [2014-11-00; online 2014-09-14]
Affiliated researcher
Abolished InsP3R2 function inhibits sweat secretion in both humans and mice.
Klar J, Hisatsune C, Baig SM, ..., Mikoshiba K, Dahl N
J. Clin. Invest. 124 (11) 4773-4780 [2014-11-00; online 2014-10-20]
Affiliated researcher
Designing a multimer allergen for diagnosis and immunotherapy of dog allergic patients.
Nilsson OB, Neimert-Andersson T, Bronge M, ..., van Hage M, Grönlund H
PLoS ONE 9 (10) e111041 [2014-10-29; online 2014-10-29]
Affiliated researcher
Ligand-based target prediction with signature fingerprints.
Alvarsson J, Eklund M, Engkvist O, ..., Wikberg JE, Noeske T
J Chem Inf Model 54 (10) 2647-2653 [2014-10-27; online 2014-10-03]
Affiliated researcher
Structure and mechanism of Zn2+-transporting P-type ATPases.
Wang K, Sitsel O, Meloni G, ..., Nissen P, Gourdon P
Nature 514 (7523) 518-522 [2014-10-23; online 2014-08-17]
Affiliated researcher
Allelic expression mapping across cellular lineages to establish impact of non-coding SNPs.
Adoue V, Schiavi A, Light N, ..., Syvänen AC, Pastinen T
Mol Syst Biol 10 (-) 754 [2014-10-16; online 2014-10-16]
Affiliated researcher
Crux: rapid open source protein tandem mass spectrometry analysis.
McIlwain S, Tamura K, Kertesz-Farkas A, ..., MacCoss MJ, Noble WS
J. Proteome Res. 13 (10) 4488-4491 [2014-10-03; online 2014-09-09]
Affiliated researcher
Biofuels. Altered sterol composition renders yeast thermotolerant.
Caspeta L, Chen Y, Ghiaci P, ..., Petranovic D, Nielsen J
Science 346 (6205) 75-78 [2014-10-03; online 2014-10-02]
Affiliated researcher
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.
Perry JR, Day F, Elks CE, ..., Murabito JM, Ong KK
Nature 514 (7520) 92-97 [2014-10-02; online 2014-07-23]
Affiliated researcher
Specific targeting of human caspases using designed ankyrin repeat proteins.
Flütsch A, Schroeder T, Barandun J, ..., Bühlmann M, Grütter MG
Biol. Chem. 395 (10) 1243-1252 [2014-10-00; online 2014-08-26]
Jonas Barandun SciLifeLab Fellow
Phenotype standardization for statin-induced myotoxicity.
Alfirevic A, Neely D, Armitage J, ..., Palmer CN, Pirmohamed M
Clin. Pharmacol. Ther. 96 (4) 470-476 [2014-10-00; online 2014-06-04]
Affiliated researcher
Effect of cardiovascular drugs on mortality in atrial fibrillation and chronic heart failure.
Wändell P, Carlsson AC, Sundquist J, ..., Bottai M, Sundquist K
Scand. Cardiovasc. J. 48 (5) 291-298 [2014-10-00; online 2014-08-06]
Affiliated researcher
Design of a general-purpose European compound screening library for EU-OPENSCREEN.
Horvath D, Lisurek M, Rupp B, ..., Quintana J, Frank R
ChemMedChem 9 (10) 2309-2326 [2014-10-00; online 2014-07-15]
Affiliated researcher
BRCA2 and RAD51 promote double-strand break formation and cell death in response to gemcitabine.
Jones RM, Kotsantis P, Stewart GS, Groth P, Petermann E
Mol. Cancer Ther. 13 (10) 2412-2421 [2014-10-00; online 2014-07-22]
Affiliated researcher
The Chironomus tentans genome sequence and the organization of the Balbiani ring genes.
Kutsenko A, Svensson T, Nystedt B, ..., Visa N, Wieslander L
BMC Genomics 15 (-) 819 [2014-09-27; online 2014-09-27]
Affiliated researcher
Glial origin of mesenchymal stem cells in a tooth model system.
Kaukua N, Shahidi MK, Konstantinidou C, ..., Fried K, Adameyko I
Nature 513 (7519) 551-554 [2014-09-25; online 2014-07-27]
Affiliated researcher
The genomic substrate for adaptive radiation in African cichlid fish.
Brawand D, Wagner CE, Li YI, ..., Seehausen O, Di Palma F
Nature 513 (7518) 375-381 [2014-09-18; online 2014-09-03]
Affiliated researcher
A universal approach to prepare reagents for DNA-assisted protein analysis.
Yan J, Gu GJ, Jost C, ..., Landegren U, Kamali-Moghaddam M
PLoS ONE 9 (9) e108061 [2014-09-18; online 2014-09-18]
Affiliated researcher
Spontaneous transmembrane helix insertion thermodynamically mimics translocon-guided insertion.
Ulmschneider MB, Ulmschneider JP, Schiller N, ..., von Heijne G, White SH
Nat Commun 5 (-) 4863 [2014-09-10; online 2014-09-10]
Affiliated researcher
The prognostic value and therapeutic target role of stathmin-1 in urinary bladder cancer.
Hemdan T, Lindén M, Lind SB, ..., Malmström PU, Segersten U
Br. J. Cancer 111 (6) 1180-1187 [2014-09-09; online 2014-07-29]
Affiliated researcher
Antibiotic treatment selects for cooperative virulence of Salmonella typhimurium.
Diard M, Sellin ME, Dolowschiak T, ..., Ackermann M, Hardt WD
Curr. Biol. 24 (17) 2000-2005 [2014-09-08; online 2014-08-14]
Mikael Sellin SciLifeLab Fellow
Proteomics of neuropathic pain: proteins and signaling pathways affected in a rat model.
Sui P, Watanabe H, Ossipov MH, ..., Artemenko K, Bergquist J
J. Proteome Res. 13 (9) 3957-3965 [2014-09-05; online 2014-07-28]
Affiliated researcher
PconsFold: improved contact predictions improve protein models.
Michel M, Hayat S, Skwark MJ, ..., Marks DS, Elofsson A
Bioinformatics 30 (17) i482-i488 [2014-09-01; online 2014-08-28]
Affiliated researcher
High frequency of cytolytic 21-hydroxylase-specific CD8+ T cells in autoimmune Addison's disease patients.
Dawoodji A, Chen JL, Shepherd D, ..., Kämpe O, Cerundolo V
J. Immunol. 193 (5) 2118-2126 [2014-09-01; online 2014-07-25]
Affiliated researcher
Archaeal MBF1 binds to 30S and 70S ribosomes via its helix-turn-helix domain.
Blombach F, Launay H, Snijders AP, ..., Christodoulou J, van der Oost J
Biochem. J. 462 (2) 373-384 [2014-09-01; online 2014-05-16]
Affiliated researcher
Whole ARX gene duplication is compatible with normal intellectual development.
Popovici C, Busa T, Boute O, ..., Moncla A, Philip N
Am. J. Med. Genet. A 164A (9) 2324-2327 [2014-09-00; online 2014-07-07]
Affiliated researcher
The cellular thermal shift assay for evaluating drug target interactions in cells.
Jafari R, Almqvist H, Axelsson H, ..., Nordlund P, Martinez Molina D
Nat Protoc 9 (9) 2100-2122 [2014-09-00; online 2014-08-07]
Affiliated researcher
Point-of-care vertical flow allergen microarray assay: proof of concept.
Chinnasamy T, Segerink LI, Nystrand M, Gantelius J, Andersson Svahn H
Clin. Chem. 60 (9) 1209-1216 [2014-09-00; online 2014-07-08]
Affiliated researcher
Picocyanobacteria containing a novel pigment gene cluster dominate the brackish water Baltic Sea.
Larsson J, Celepli N, Ininbergs K, ..., Bergman B, Ekman M
ISME J 8 (9) 1892-1903 [2014-09-00; online 2014-03-13]
Affiliated researcher
Mechanisms underlying mutational signatures in human cancers.
Helleday T, Eshtad S, Nik-Zainal S
Nat. Rev. Genet. 15 (9) 585-598 [2014-09-00; online 2014-07-01]
Affiliated researcher
Investigating population history using temporal genetic differentiation.
Skoglund P, Sjödin P, Skoglund T, Lascoux M, Jakobsson M
Mol. Biol. Evol. 31 (9) 2516-2527 [2014-09-00; online 2014-06-17]
Affiliated researcher
Genome of the avirulent human-infective trypanosome--Trypanosoma rangeli.
Stoco PH, Wagner G, Talavera-Lopez C, ..., de Vasconcelos AT, Grisard EC
PLoS Negl Trop Dis 8 (9) e3176 [2014-09-00; online 2014-09-18]
Affiliated researcher
Diabetes and psychiatric illness in the total population of Stockholm.
Wändell P, Ljunggren G, Wahlström L, Carlsson AC
J Psychosom Res 77 (3) 169-173 [2014-09-00; online 2014-06-28]
Affiliated researcher
Bacterial nanoscale cultures for phenotypic multiplexed antibiotic susceptibility testing.
Weibull E, Antypas H, Kjäll P, ..., Andersson-Svahn H, Richter-Dahlfors A
J. Clin. Microbiol. 52 (9) 3310-3317 [2014-09-00; online 2014-07-02]
Affiliated researcher
Splicing in the human brain.
Zaghlool A, Ameur A, Cavelier L, Feuk L
Int. Rev. Neurobiol. 116 (-) 95-125 [2014-08-31; online 2014-08-31]
Affiliated researcher
Rabbit genome analysis reveals a polygenic basis for phenotypic change during domestication.
Carneiro M, Rubin CJ, Di Palma F, ..., Lindblad-Toh K, Andersson L
Science 345 (6200) 1074-1079 [2014-08-29; online 2014-08-30]
Affiliated researcher
Inhibition of glutamine synthetase: a potential drug target in Mycobacterium tuberculosis.
Mowbray SL, Kathiravan MK, Pandey AA, Odell LR
Molecules 19 (9) 13161-13176 [2014-08-26; online 2014-08-26]
Affiliated researcher
Lack of evidence for a role of islet autoimmunity in the aetiology of canine diabetes mellitus.
Ahlgren KM, Fall T, Landegren N, ..., Lernmark Å, Kämpe O
PLoS ONE 9 (8) e105473 [2014-08-25; online 2014-08-25]
Affiliated researcher
Winter bloom of a rare betaproteobacterium in the Arctic Ocean.
Alonso-Sáez L, Zeder M, Harding T, ..., Bertilsson S, Pedrós-Alió C
Front Microbiol 5 (-) 425 [2014-08-20; online 2014-08-20]
Affiliated researcher
Understanding functional miRNA-target interactions in vivo by site-specific genome engineering.
Bassett AR, Azzam G, Wheatley L, ..., Sauka-Spengler T, Fulga TA
Nat Commun 5 (-) 4640 [2014-08-19; online 2014-08-19]
Affiliated researcher
Meta-analysis in more than 17,900 cases of ischemic stroke reveals a novel association at 12q24.12.
Kilarski LL, Achterberg S, Devan WJ, ..., Bevan S, GARNET Collaborative Research Group, Wellcome Trust Case Control Consortium 2, Australian Stroke Genetic Collaborative, the METASTROKE Consortium, and the International Stroke Genetics Consortium
Neurology 83 (8) 678-685 [2014-08-19; online 2014-07-16]
Affiliated researcher
Evaluation of exome sequencing to estimate tumor burden in plasma.
Klevebring D, Neiman M, Sundling S, ..., Grönberg H, Lindberg J
PLoS ONE 9 (8) e104417 [2014-08-18; online 2014-08-18]
Affiliated researcher
Immunogenetic studies of chronic lymphocytic leukemia: revelations and speculations about ontogeny and clinical evolution.
Vardi A, Agathangelidis A, Sutton LA, ..., Rosenquist R, Stamatopoulos K
Cancer Res. 74 (16) 4211-4216 [2014-08-15; online 2014-07-29]
Affiliated researcher
The positive inside rule is stronger when followed by a transmembrane helix.
Virkki MT, Peters C, Nilsson D, ..., Wallner B, Elofsson A
J. Mol. Biol. 426 (16) 2982-2991 [2014-08-12; online 2014-06-10]
Affiliated researcher
Eye movements in ephedrone-induced parkinsonism.
Bonnet C, Rusz J, Megrelishvili M, ..., Gaymard B, Růžička E
PLoS ONE 9 (8) e104784 [2014-08-12; online 2014-08-12]
Affiliated researcher
A simple repeat polymorphism in the MITF-M promoter is a key regulator of white spotting in dogs.
Baranowska Körberg I, Sundström E, Meadows JR, ..., Andersson G, Andersson L
PLoS ONE 9 (8) e104363 [2014-08-12; online 2014-08-12]
Affiliated researcher
Urinary kidney injury molecule-1 and the risk of cardiovascular mortality in elderly men.
Carlsson AC, Larsson A, Helmersson-Karlqvist J, ..., Sundström J, Ärnlöv J
Clin J Am Soc Nephrol 9 (8) 1393-1401 [2014-08-07; online 2014-06-12]
Affiliated researcher
A whole-brain atlas of inputs to serotonergic neurons of the dorsal and median raphe nuclei.
Pollak Dorocic I, Fürth D, Xuan Y, ..., Carlén M, Meletis K
Neuron 83 (3) 663-678 [2014-08-06; online 2014-08-08]
Iskra Pollak Dorocic SciLifeLab Fellow
Differences in gene expression between mouse and human for dynamically regulated genes in early embryo.
Madissoon E, Töhönen V, Vesterlund L, ..., Hovatta O, Kere J
PLoS ONE 9 (8) e102949 [2014-08-04; online 2014-08-04]
Affiliated researcher
HAS2 and CD44 in breast tumorigenesis.
Heldin P, Basu K, Kozlova I, Porsch H
Adv. Cancer Res. 123 (-) 211-229 [2014-08-02; online 2014-08-02]
Affiliated researcher
High- and low-throughput scoring of fat mass and body fat distribution in C. elegans.
Wählby C, Conery AL, Bray MA, ..., Carpenter AE, O'Rourke EJ
Methods 68 (3) 492-499 [2014-08-01; online 2014-04-28]
Affiliated researcher
Analysis of candidate genes for lineage-specific expression changes in humans and primates.
Lindskog C, Kuhlwilm M, Davierwala A, ..., Pääbo S, Pontén F
J. Proteome Res. 13 (8) 3596-3606 [2014-08-01; online 2014-07-15]
Affiliated researcher
Treatment of osteogenesis imperfecta in adults.
Lindahl K, Langdahl B, Ljunggren Ö, Kindmark A
Eur. J. Endocrinol. 171 (2) R79-R90 [2014-08-00; online 2014-04-23]
Affiliated researcher
The PARP inhibitor Olaparib disrupts base excision repair of 5-aza-2'-deoxycytidine lesions.
Orta ML, Höglund A, Calderón-Montaño JM, ..., López-lázaro M, Helleday T
Nucleic Acids Res. 42 (14) 9108-9120 [2014-08-00; online 2014-07-29]
Affiliated researcher
Spatial control of membrane receptor function using ligand nanocalipers.
Shaw A, Lundin V, Petrova E, ..., Högberg B, Teixeira AI
Nat. Methods 11 (8) 841-846 [2014-08-00; online 2014-07-06]
Erik Benson SciLifeLab Fellow
Self-healing hybrid nanocomposites consisting of bisphosphonated hyaluronan and calcium phosphate nanoparticles.
Nejadnik MR, Yang X, Bongio M, ..., Ossipov D, Leeuwenburgh SC
Biomaterials 35 (25) 6918-6929 [2014-08-00; online 2014-05-24]
Affiliated researcher
Plasma profiling reveals three proteins associated to amyotrophic lateral sclerosis.
Häggmark A, Mikus M, Mohsenchian A, ..., Kuźma-Kozakiewicz M, Nilsson P
Ann Clin Transl Neurol 1 (8) 544-553 [2014-08-00; online 2014-07-14]
Affiliated researcher
MDM2 promotor polymorphism and disease characteristics in chronic lymphocytic leukemia: results of an individual patient data-based meta-analysis.
Benner A, Mansouri L, Rossi D, ..., Zenz T, European Research Initiative on CLL (ERIC)
Haematologica 99 (8) 1285-1291 [2014-08-00; online 2014-08-02]
Affiliated researcher
Influence of coronary artery disease-associated genetic variants on risk of venous thromboembolism.
Bruzelius M, Strawbridge RJ, Trégouët DA, ..., Odeberg J, Hamsten A
Thromb. Res. 134 (2) 426-432 [2014-08-00; online 2014-04-04]
Affiliated researcher
Identification of novel sphingolipid-binding motifs in mammalian membrane proteins.
Björkholm P, Ernst AM, Hacke M, ..., Brügger B, von Heijne G
Biochim. Biophys. Acta 1838 (8) 2066-2070 [2014-08-00; online 2014-05-02]
Affiliated researcher
A cis-regulatory mutation of PDSS2 causes silky-feather in chickens.
Feng C, Gao Y, Dorshorst B, ..., Hu X, Li N
PLoS Genet 10 (8) e1004576 [2014-08-00; online 2014-08-28]
Affiliated researcher
Nuclease-assisted suppression of human DNA background in sepsis.
Song Y, Giske CG, Gille-Johnson P, ..., Lundeberg J, Gyarmati P
PLoS ONE 9 (7) e103610 [2014-07-30; online 2014-07-30]
Affiliated researcher
On-chip detection of rolling circle amplified DNA molecules from Bacillus globigii spores and Vibrio cholerae.
Østerberg FW, Rizzi G, Donolato M, ..., Svedlindh P, Hansen MF
Small 10 (14) 2877-2882 [2014-07-23; online 2014-03-10]
Affiliated researcher
The molecular mode of action of the active component of chili pepper
Elokely K, Palovcak E, Delemotte L, Carnevale V, Klein M
Planta Med 80 (10) - [2014-07-14; online 2014-07-14]
Lucie Delemotte SciLifeLab Fellow
Proline N-oxides: modulators of the 3D conformation of linear peptides through "NO-turns".
Farahani MD, Honarparvar B, Albericio F, ..., Arvidsson PI, Kruger HG
Org. Biomol. Chem. 12 (25) 4479-4490 [2014-07-07; online 2014-05-23]
Affiliated researcher
Increased C-telopeptide cross-linking of tendon type I collagen in fibromodulin-deficient mice.
Kalamajski S, Liu C, Tillgren V, ..., Weis M, Eyre DR
J. Biol. Chem. 289 (27) 18873-18879 [2014-07-04; online 2014-05-21]
Affiliated researcher
Transcriptome analysis reveals signature of adaptation to landscape fragmentation.
Somervuo P, Kvist J, Ikonen S, ..., Ahola V, Hanski I
PLoS ONE 9 (7) e101467 [2014-07-02; online 2014-07-02]
Affiliated researcher
Peptide-independent stabilization of MHC class I molecules breaches cellular quality control.
Hein Z, Uchtenhagen H, Abualrous ET, ..., Springer S, Boulanger D
J. Cell. Sci. 127 (Pt 13) 2885-2897 [2014-07-01; online 2014-05-07]
Affiliated researcher
l-Proline organocatalyzed Michael synthesis of monobactam and carbapenem β-lactam cores
Khanyase S, Naicker T, Maguire GEM, ..., Arvidsson PI, Govender T
Tetrahedron: Asymmetry 25 (13-14) 969-973 [2014-07-00; online 2014-07-00]
Affiliated researcher
SIRT1 promoter polymorphisms as clinical modifiers on systemic lupus erythematosus.
Consiglio CR, Juliana da Silveira S, Monticielo OA, ..., Brenol JC, Chies JA
Mol. Biol. Rep. 41 (7) 4233-4239 [2014-07-00; online 2014-02-26]
Camila Consiglio DDLS Fellow
Pre-clinical evaluation of [(68)Ga]Ga-DO3A-VS-Cys(40)-Exendin-4 for imaging of insulinoma.
Selvaraju RK, Velikyan I, Asplund V, ..., Korsgren O, Eriksson O
Nucl. Med. Biol. 41 (6) 471-476 [2014-07-00; online 2014-03-29]
Olof Eriksson SciLifeLab Fellow
Microfluidics for nano-pathophysiology.
Sato K, Sasaki N, Svahn HA, Sato K
Adv. Drug Deliv. Rev. 74 (-) 115-121 [2014-07-00; online 2013-08-31]
Affiliated researcher
Improving ITS sequence data for identification of plant pathogenic fungi
Nilsson RH, Hyde KD, Pawłowska J, ..., Kõljalg U, Abarenkov K
Fungal Diversity 67 (1) 11-19 [2014-07-00; online 2014-05-15]
DDLS Fellow Johan Bengtsson-Palme
Hijacking of host calreticulin is required for the white spot syndrome virus replication cycle.
Watthanasurorot A, Guo E, Tharntada S, ..., Söderhäll K, Söderhäll I
J. Virol. 88 (14) 8116-8128 [2014-07-00; online 2014-05-07]
Affiliated researcher
Genome-wide association analysis identifies six new loci associated with forced vital capacity.
Loth DW, Soler Artigas M, Gharib SA, ..., Tobin MD, London SJ
Nat. Genet. 46 (7) 669-677 [2014-07-00; online 2014-06-15]
Affiliated researcher
Forensic informativity of ~3000 bp of coding sequence of domestic dog mtDNA.
Angleby H, Oskarsson M, Pang J, ..., Webb KM, Savolainen P
J. Forensic Sci. 59 (4) 898-908 [2014-07-00; online 2014-05-11]
Affiliated researcher
Folding of Aquaporin 1: multiple evidence that helix 3 can shift out of the membrane core.
Virkki MT, Agrawal N, Edsbäcker E, ..., Elofsson A, Kauko A
Protein Sci. 23 (7) 981-992 [2014-07-00; online 2014-05-14]
Affiliated researcher
Deleterious mutation in FDX1L gene is associated with a novel mitochondrial muscle myopathy.
Spiegel R, Saada A, Halvardson J, ..., Feuk L, Elpeleg O
Eur. J. Hum. Genet. 22 (7) 902-906 [2014-07-00; online 2013-11-27]
Affiliated researcher
CXCR4 Antagonists: A Screening Strategy for Identification of Functionally Selective Ligands.
Castaldo C, Benicchi T, Otrocka M, ..., Varrone M, Porcari V
J Biomol Screen 19 (6) 859-869 [2014-07-00; online 2014-03-14]
Affiliated researcher
Affinity proteomics within rare diseases: a BIO-NMD study for blood biomarkers of muscular dystrophies.
Ayoglu B, Chaouch A, Lochmüller H, ..., Nilsson P, Al-Khalili Szigyarto C
EMBO Mol Med 6 (7) 918-936 [2014-07-00; online 2014-06-13]
Affiliated researcher
A constrained multi-objective surrogate-based optimization algorithm
Singh P, Couckuyt I, Ferranti F, Dhaene T
- - (-) - [2014-07-00; online 2014-07-00]
Prashant Singh SciLifeLab Fellow
A universal genomic coordinate translator for comparative genomics.
Zamani N, Sundström G, Meadows JR, ..., Haas BJ, Grabherr MG
BMC Bioinformatics 15 (-) 227 [2014-06-30; online 2014-06-30]
Affiliated researcher
Large tilts in transmembrane helices can be induced during tertiary structure formation.
Virkki M, Boekel C, Illergård K, ..., von Heijne G, Nilsson I
J. Mol. Biol. 426 (13) 2529-2538 [2014-06-26; online 2014-04-30]
Affiliated researcher
Fabrication and functionalization of PCB gold electrodes suitable for DNA-based electrochemical sensing.
Salvo P, Henry OY, Dhaenens K, ..., O'Sullivan CK, Vanfleteren J
Biomed Mater Eng 24 (4) 1705-1714 [2014-06-21; online 2014-06-21]
Affiliated researcher
The genomic landscape underlying phenotypic integrity in the face of gene flow in crows.
Poelstra JW, Vijay N, Bossu CM, ..., Grabherr MG, Wolf JB
Science 344 (6190) 1410-1414 [2014-06-20; online 2014-06-21]
Affiliated researcher
Rational design and validation of a Tip60 histone acetyltransferase inhibitor.
Gao C, Bourke E, Scobie M, ..., Lowndes NF, Brown JA
Sci Rep 4 (-) 5372 [2014-06-20; online 2014-06-20]
Affiliated researcher
Functional association networks as priors for gene regulatory network inference.
Studham ME, Tjärnberg A, Nordling TE, Nelander S, Sonnhammer EL
Bioinformatics 30 (12) i130-i138 [2014-06-15; online 2014-06-17]
Affiliated researcher
Boosting of HIV-1 neutralizing antibody responses by a distally related retroviral envelope protein.
Uchtenhagen H, Schiffner T, Bowles E, ..., Stewart-Jones G, Spetz AL
J. Immunol. 192 (12) 5802-5812 [2014-06-15; online 2014-05-14]
Affiliated researcher
Tyrosine phosphorylation profiling via in situ proximity ligation assay.
Elfineh L, Classon C, Asplund A, ..., Kamali-Moghaddam M, Lind SB
BMC Cancer 14 (-) 435 [2014-06-13; online 2014-06-13]
Affiliated researcher
Analysis of structural diversity in wolf-like canids reveals post-domestication variants.
Ramirez O, Olalde I, Berglund J, ..., Vilà C, Marques-Bonet T
BMC Genomics 15 (-) 465 [2014-06-12; online 2014-06-12]
Affiliated researcher
QUANTIFICATION OF THE 3D MORPHOLOGY OF THE BONE CELL NETWORK FROM SYNCHROTRON MICRO-CT IMAGES
Dong P, Pacureanu A, Zuluaga MA, ..., Grimal Q, Peyrin F
Image Anal Stereol 33 (2) 157 [2014-06-07; online 2014-06-07]
Affiliated researcher
Role of Na,K-ATPase α1 and α2 isoforms in the support of astrocyte glutamate uptake.
Illarionova NB, Illarionava NB, Brismar H, Aperia A, Gunnarson E
PLoS ONE 9 (6) e98469 [2014-06-05; online 2014-06-05]
Affiliated researcher
Early B cell factor 1 regulates adipocyte morphology and lipolysis in white adipose tissue.
Gao H, Mejhert N, Fretz JA, ..., Horowitz MC, Arner P
Cell Metab. 19 (6) 981-992 [2014-06-03; online 2014-05-22]
Affiliated researcher
Scanning inverse fluorescence correlation spectroscopy.
Bergstrand J, Rönnlund D, Widengren J, Wennmalm S
Opt Express 22 (11) 13073-13090 [2014-06-02; online 2014-06-13]
Affiliated researcher
The human testis-specific proteome defined by transcriptomics and antibody-based profiling.
Djureinovic D, Fagerberg L, Hallström B, ..., Uhlén M, Pontén F
Mol. Hum. Reprod. 20 (6) 476-488 [2014-06-00; online 2014-03-05]
Affiliated researcher
The age and genomic integrity of neurons after cortical stroke in humans.
Huttner HB, Bergmann O, Salehpour M, ..., Lundeberg J, Frisén J
Nat. Neurosci. 17 (6) 801-803 [2014-06-00; online 2014-04-20]
Affiliated researcher
SpliceVista, a tool for splice variant identification and visualization in shotgun proteomics data.
Zhu Y, Hultin-Rosenberg L, Forshed J, ..., Orre LM, Lehtiö J
Mol. Cell Proteomics 13 (6) 1552-1562 [2014-06-00; online 2014-04-01]
Affiliated researcher
Soluble TNF receptors and kidney dysfunction in the elderly.
Carlsson AC, Larsson TE, Helmersson-Karlqvist J, ..., Lind L, Ärnlöv J
J. Am. Soc. Nephrol. 25 (6) 1313-1320 [2014-06-00; online 2014-02-07]
Affiliated researcher
Nucleosome regulatory dynamics in response to TGFβ.
Enroth S, Andersson R, Bysani M, ..., Komorowski J, Wadelius C
Nucleic Acids Res. 42 (11) 6921-6934 [2014-06-00; online 2014-04-25]
Affiliated researcher
Molecular evolution of GPCRs: Somatostatin/urotensin II receptors.
Tostivint H, Ocampo Daza D, Bergqvist CA, ..., Lihrmann I, Larhammar D
J. Mol. Endocrinol. 52 (3) T61-T86 [2014-06-00; online 2014-04-16]
Affiliated researcher
Low gut microbiota diversity in early infancy precedes asthma at school age.
Abrahamsson TR, Jakobsson HE, Andersson AF, ..., Engstrand L, Jenmalm MC
Clin. Exp. Allergy 44 (6) 842-850 [2014-06-00; online 2013-12-18]
Affiliated researcher
Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity.
Dimas AS, Lagou V, Barker A, ..., Prokopenko I, MAGIC Investigators
Diabetes 63 (6) 2158-2171 [2014-06-00; online 2013-12-02]
Affiliated researcher
DNA methylation and body-mass index: a genome-wide analysis
Dick KJ, Nelson CP, Tsaprouni L, ..., Deloukas P, Samani NJ
The Lancet 383 (9933) 1990-1998 [2014-06-00; online 2014-06-00]
Affiliated researcher
Characterization of Leukocyte Formin FMNL1 Expression in Human Tissues.
Gardberg M, Heuser VD, Iljin K, ..., Uhlen M, Carpén O
J. Histochem. Cytochem. 62 (6) 460-470 [2014-06-00; online 2014-04-03]
Affiliated researcher
Why have small multidrug resistance proteins not evolved into fused, internally duplicated structures?
Lloris-Garcerá P, Seppälä S, Slusky JS, Rapp M, von Heijne G
J. Mol. Biol. 426 (11) 2246-2254 [2014-05-29; online 2014-03-30]
Affiliated researcher
Trait-based approaches for understanding microbial biodiversity and ecosystem functioning.
Krause S, Le Roux X, Niklaus PA, ..., Philippot L, Bodelier PL
Front Microbiol 5 (-) 251 [2014-05-27; online 2014-05-27]
Affiliated researcher
Private haplotypes can reveal local adaptation.
Sjöstrand AE, Sjödin P, Jakobsson M
BMC Genet. 15 (-) 61 [2014-05-22; online 2014-05-22]
Affiliated researcher
A lateral flow paper microarray for rapid allergy point of care diagnostics.
Chinnasamy T, Segerink LI, Nystrand M, Gantelius J, Svahn HA
Analyst 139 (10) 2348-2354 [2014-05-21; online 2014-04-03]
Affiliated researcher
Genomic diversity and admixture differs for Stone-Age Scandinavian foragers and farmers.
Skoglund P, Malmström H, Omrak A, ..., Götherström A, Jakobsson M
Science 344 (6185) 747-750 [2014-05-16; online 2014-04-24]
Affiliated researcher
Proteomics analysis of melanoma metastases: association between S100A13 expression and chemotherapy resistance.
Azimi A, Pernemalm M, Frostvik Stolt M, ..., Egyházi Brage S, Hertzman Johansson C
Br. J. Cancer 110 (10) 2489-2495 [2014-05-13; online 2014-04-10]
Affiliated researcher
Chemical strategies for development of ATR inhibitors.
Llona-Minguez S, Höglund A, Jacques SA, Koolmeister T, Helleday T
Expert Rev Mol Med 16 (-) e10 [2014-05-09; online 2014-05-09]
Affiliated researcher
Uterine leiomyoma-linked MED12 mutations disrupt mediator-associated CDK activity.
Turunen M, Spaeth JM, Keskitalo S, ..., Taipale J, Boyer TG
Cell Reports 7 (3) 654-660 [2014-05-08; online 2014-04-18]
Affiliated researcher
DNA mismatch repair gene MSH6 implicated in determining age at natural menopause.
Perry JR, Hsu YH, Chasman DI, ..., Karasik D, Murray A
Hum. Mol. Genet. 23 (9) 2490-2497 [2014-05-01; online 2013-12-19]
Affiliated researcher
Quality control and conduct of genome-wide association meta-analyses.
Winkler TW, Day FR, Croteau-Chonka DC, ..., Loos RJ, Genetic Investigation of Anthropometric Traits (GIANT) Consortium
Nat Protoc 9 (5) 1192-1212 [2014-05-00; online 2014-04-24]
Affiliated researcher
Protein biomarker validation via proximity ligation assays.
Blokzijl A, Nong R, Darmanis S, ..., Landegren U, Kamali-Moghaddam M
Biochim. Biophys. Acta 1844 (5) 933-939 [2014-05-00; online 2013-08-07]
Affiliated researcher
Pharmacokinetics for topically applied caffeine in the rat.
Kronschläger M, Forsman E, Yu Z, ..., Bergquist J, Söderberg P
Exp. Eye Res. 122 (-) 94-101 [2014-05-00; online 2014-04-01]
Affiliated researcher
Inflammatory biomarker pentraxin 3 (PTX3) in relation to obesity, body fat depots and weight loss.
Witasp A, Carrero JJ, Michaëlsson K, ..., Stenvinkel P, Arnlöv J
Obesity (Silver Spring) 22 (5) 1373-1379 [2014-05-00; online 2014-01-25]
Affiliated researcher
Increased urinary cystatin C indicated higher risk of cardiovascular death in a community cohort.
Helmersson-Karlqvist J, Ärnlöv J, Carlsson AC, Härmä J, Larsson A
Atherosclerosis 234 (1) 108-113 [2014-05-00; online 2014-02-28]
Affiliated researcher
GRM1 is upregulated through gene fusion and promoter swapping in chondromyxoid fibroma.
Nord KH, Lilljebjörn H, Vezzi F, ..., Hogendoorn PC, Szuhai K
Nat. Genet. 46 (5) 474-477 [2014-05-00; online 2014-03-23]
Affiliated researcher
Engineering synergy in biotechnology.
Nielsen J, Fussenegger M, Keasling J, ..., Prather K, Palsson B
Nat. Chem. Biol. 10 (5) 319-322 [2014-05-00; online 2014-04-20]
Affiliated researcher
Dean flow-coupled inertial focusing in curved channels.
Ramachandraiah H, Ardabili S, Faridi AM, ..., Mårtensson G, Russom A
Biomicrofluidics 8 (3) 034117 [2014-05-00; online 2014-06-24]
Affiliated researcher
CCL2 mediates anti-fibrotic effects in human fibroblasts independently of CCR2.
Kalderén C, Stadler C, Forsgren M, ..., Sydow-Bäckman M, Svensson Gelius S
Int. Immunopharmacol. 20 (1) 66-73 [2014-05-00; online 2014-02-26]
Affiliated researcher
Assessing the maximum contribution from ancient populations.
Sjödin P, Skoglund P, Jakobsson M
Mol. Biol. Evol. 31 (5) 1248-1260 [2014-05-00; online 2014-02-03]
Affiliated researcher
A Bayesian method for analyzing lateral gene transfer.
Sjöstrand J, Tofigh A, Daubin V, ..., Sennblad B, Lagergren J
Syst. Biol. 63 (3) 409-420 [2014-05-00; online 2014-02-20]
Affiliated researcher
Mutation analysis of components of the Mediator kinase module in MED12 mutation-negative uterine leiomyomas.
Mäkinen N, Heinonen HR, Sjöberg J, ..., Vahteristo P, Aaltonen LA
Br. J. Cancer 110 (9) 2246-2249 [2014-04-29; online 2014-03-18]
Affiliated researcher
Lactase persistence alleles reveal partial East African ancestry of southern African Khoe pastoralists.
Breton G, Schlebusch CM, Lombard M, ..., Soodyall H, Jakobsson M
Curr. Biol. 24 (8) 852-858 [2014-04-14; online 2014-04-03]
Affiliated researcher
Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy.
Huber KV, Salah E, Radic B, ..., Knapp S, Superti-Furga G
Nature 508 (7495) 222-227 [2014-04-10; online 2014-04-02]
Affiliated researcher
MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool.
Gad H, Koolmeister T, Jemth AS, ..., Berglund UW, Helleday T
Nature 508 (7495) 215-221 [2014-04-10; online 2014-04-02]
Affiliated researcher
ZBED6 modulates the transcription of myogenic genes in mouse myoblast cells.
Jiang L, Wallerman O, Younis S, ..., Andersson G, Andersson L
PLoS ONE 9 (4) e94187 [2014-04-08; online 2014-04-08]
Affiliated researcher
Evidence for the biogenesis of more than 1,000 novel human microRNAs.
Friedländer MR, Lizano E, Houben AJ, ..., Martí E, Estivill X
Genome Biol. 15 (4) R57 [2014-04-07; online 2014-04-07]
Marc Friedländer SciLifeLab Fellow
RNA- and antibody-based profiling of the human proteome with focus on chromosome 19.
Stadler C, Fagerberg L, Sivertsson Å, ..., Lundberg E, Uhlén M
J. Proteome Res. 13 (4) 2019-2027 [2014-04-04; online 2014-03-12]
Affiliated researcher
WNT5A-mediated β-catenin-independent signalling is a novel regulator of cancer cell metabolism.
Sherwood V, Chaurasiya SK, Ekström EJ, ..., James P, Andersson T
Carcinogenesis 35 (4) 784-794 [2014-04-00; online 2013-11-30]
Affiliated researcher
Telomere length in circulating leukocytes is associated with lung function and disease.
Albrecht E, Sillanpää E, Karrasch S, ..., Jarvelin MR, Schulz H
Eur. Respir. J. 43 (4) 983-992 [2014-04-00; online 2013-12-05]
Affiliated researcher
Organocatalytic Mannich Reactions on a Carbapenem Core - Synthesis of Mannich Bases and Bicyclic Diazanonanes
Cele ZED, Pawar SA, Naicker T, ..., Kruger HG, Govender T
Eur. J. Org. Chem. 2014 (11) 2253-2260 [2014-04-00; online 2014-02-06]
Affiliated researcher
Loss-of-function mutations in SLC30A8 protect against type 2 diabetes.
Flannick J, Thorleifsson G, Beer NL, ..., Stefansson K, Altshuler D
Nat. Genet. 46 (4) 357-363 [2014-04-00; online 2014-03-02]
Affiliated researcher
Intracellular concentration of the tyrosine kinase inhibitor imatinib in gastrointestinal stromal tumor cells.
Berglund E, Ubhayasekera SJ, Karlsson F, ..., Bergquist J, Bränström R
Anticancer Drugs 25 (4) 415-422 [2014-04-00; online 2013-12-24]
Affiliated researcher
Interplay of overweight and insulin resistance on hypertension development.
Lytsy P, Ingelsson E, Lind L, Arnlöv J, Sundström J
J. Hypertens. 32 (4) 834-839 [2014-04-00; online 2013-12-29]
Affiliated researcher
Cell line profiling to improve monoclonal antibody production.
Kang S, Ren D, Xiao G, ..., Bondarenko PV, Deshpande R
Biotechnol. Bioeng. 111 (4) 748-760 [2014-04-00; online 2013-11-19]
Affiliated researcher
Caspase-1-like regulation of the proPO-system and role of ppA and caspase-1-like cleaved peptides from proPO in innate immunity.
Jearaphunt M, Noonin C, Jiravanichpaisal P, ..., Söderhäll I, Söderhäll K
PLoS Pathog 10 (4) e1004059 [2014-04-00; online 2014-04-10]
Affiliated researcher
Affinity proteomics reveals elevated muscle proteins in plasma of children with cerebral malaria.
Bachmann J, Burté F, Pramana S, ..., Fernandez-Reyes D, Nilsson P
PLoS Pathog 10 (4) e1004038 [2014-04-00; online 2014-04-17]
Affiliated researcher
A central role for GRB10 in regulation of islet function in man.
Prokopenko I, Poon W, Mägi R, ..., Groop L, Lyssenko V
PLoS Genet 10 (4) e1004235 [2014-04-00; online 2014-04-03]
Affiliated researcher
Structure of the Yeast Mitochondrial Large Ribosomal Subunit
Amunts A, Brown A, Bai Xc, ..., Scheres SHW, Ramakrishnan V
Science 343 (6178) 1485-1489 [2014-03-28; online 2014-03-27]
Alexey Amunts SciLifeLab Fellow
A promoter-level mammalian expression atlas.
FANTOM Consortium and the RIKEN PMI and CLST (DGT) , Forrest AR, Kawaji H, ..., Carninci P, Hayashizaki Y
Nature 507 (7493) 462-470 [2014-03-27; online 2014-03-29]
Affiliated researcher
Nanoscopic spine localization of Norbin, an mGluR5 accessory protein.
Westin L, Reuss M, Lindskog M, Aperia A, Brismar H
BMC Neurosci 15 (-) 45 [2014-03-26; online 2014-03-26]
Affiliated researcher
Arabidopsis replacement histone variant H3.3 occupies promoters of regulated genes.
Shu H, Nakamura M, Siretskiy A, ..., Gruissem W, Hennig L
Genome Biol. 15 (4) R62 [2014-03-21; online 2014-03-21]
Affiliated researcher
Two-Color RESOLFT Nanoscopy with Green and Red Fluorescent Photochromic Proteins
Lavoie-Cardinal F, Jensen NA, Westphal V, ..., Jakobs S, Hell SW
ChemPhysChem 15 (4) 655-663 [2014-03-17; online 2014-01-21]
Ilaria Testa SciLifeLab Fellow
Sequencing degraded RNA addressed by 3' tag counting.
Sigurgeirsson B, Emanuelsson O, Lundeberg J
PLoS ONE 9 (3) e91851 [2014-03-14; online 2014-03-14]
Affiliated researcher
Production of squalene in Synechocystis sp. PCC 6803.
Englund E, Pattanaik B, Ubhayasekera SJ, ..., Bergquist J, Lindberg P
PLoS ONE 9 (3) e90270 [2014-03-13; online 2014-03-13]
Affiliated researcher
An improved canine genome and a comprehensive catalogue of coding genes and non-coding transcripts.
Hoeppner MP, Lundquist A, Pirun M, ..., Lindblad-Toh K, Grabherr MG
PLoS ONE 9 (3) e91172 [2014-03-13; online 2014-03-13]
Affiliated researcher
Probing physical properties of a DNA-protein complex using nanofluidic channels.
Frykholm K, Alizadehheidari M, Fritzsche J, ..., Persson F, Westerlund F
Small 10 (5) 884-887 [2014-03-12; online 2014-01-02]
Affiliated researcher
A Generic Method for Design of Oligomer-Specific Antibodies
Brännström K, Lindhagen-Persson M, Gharibyan AL, ..., Forsgren L, Olofsson A
PLoS ONE 9 (3) e90857 [2014-03-11; online 2014-03-11]
Mikael Sellin SciLifeLab Fellow
Distinct Migration and Contact Dynamics of Resting and IL-2-Activated Human Natural Killer Cells.
Olofsson PE, Forslund E, Vanherberghen B, ..., Everhorn T, Onfelt B
Front Immunol 5 (-) 80 [2014-03-07; online 2014-03-07]
Affiliated researcher
Automated analysis of dynamic behavior of single cells in picoliter droplets.
Khorshidi MA, Rajeswari PK, Wählby C, Joensson HN, Andersson Svahn H
Lab Chip 14 (5) 931-937 [2014-03-07; online 2014-01-05]
Affiliated researcher
A chromosome-centric analysis of antibodies directed toward the human proteome using Antibodypedia.
Alm T, von Feilitzen K, Lundberg E, Sivertsson Å, Uhlén M
J. Proteome Res. 13 (3) 1669-1676 [2014-03-07; online 2014-02-17]
Affiliated researcher
Priors for X-ray in-line phase tomography of heterogeneous objects.
Langer M, Cloetens P, Hesse B, ..., Raum K, Peyrin F
Philos Trans A Math Phys Eng Sci 372 (2010) 20130129 [2014-03-06; online 2014-01-27]
Affiliated researcher
A mutation interfering with 5-lipoxygenase domain interaction leads to increased enzyme activity.
Rakonjac Ryge M, Tanabe M, Provost P, ..., Samuelsson B, Rådmark O
Arch. Biochem. Biophys. 545 (-) 179-185 [2014-03-01; online 2014-01-28]
Affiliated researcher
Melanocortin 1 Receptor-derived peptides are efficiently recognized by cytotoxic T lymphocytes from melanoma patients.
González FE, Ramírez M, Allerbring EB, ..., Achour A, Salazar-Onfray F
Immunobiology 219 (3) 189-197 [2014-03-00; online 2013-10-12]
Affiliated researcher
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium , Asian Genetic Epidemiology Network Type 2 Diabetes (AGEN-T2D) Consortium , South Asian Type 2 Diabetes (SAT2D) Consortium , ..., McCarthy MI, Morris AP
Nat. Genet. 46 (3) 234-244 [2014-03-00; online 2014-02-09]
Affiliated researcher
Differentially methylated regions in maternal and paternal uniparental disomy for chromosome 7.
Hannula-Jouppi K, Muurinen M, Lipsanen-Nyman M, ..., Greco D, Kere J
Epigenetics 9 (3) 351-365 [2014-03-00; online 2013-11-18]
Affiliated researcher
Antibody performance in western blot applications is context-dependent.
Algenäs C, Agaton C, Fagerberg L, ..., Ottosson Takanen J, Hober S
Biotechnol J 9 (3) 435-445 [2014-03-00; online 2014-01-29]
Affiliated researcher
Functional tradeoffs underpin salinity-driven divergence in microbial community composition.
Dupont CL, Larsson J, Yooseph S, ..., Venter JC, Bergman B
PLoS ONE 9 (2) e89549 [2014-02-27; online 2014-02-27]
Affiliated researcher
Gold nanowire based electrical DNA detection using rolling circle amplification.
Russell C, Welch K, Jarvius J, ..., Svedlindh P, Nilsson M
ACS Nano 8 (2) 1147-1153 [2014-02-25; online 2014-01-23]
Affiliated researcher
High-throughput screening for industrial enzyme production hosts by droplet microfluidics.
Sjostrom SL, Bai Y, Huang M, ..., Joensson HN, Andersson Svahn H
Lab Chip 14 (4) 806-813 [2014-02-21; online 2013-12-25]
Affiliated researcher
BET bromodomain inhibition of MYC-amplified medulloblastoma.
Bandopadhayay P, Bergthold G, Nguyen B, ..., Beroukhim R, Cho YJ
Clin. Cancer Res. 20 (4) 912-925 [2014-02-15; online 2013-12-02]
Affiliated researcher
The genome of a Late Pleistocene human from a Clovis burial site in western Montana.
Rasmussen M, Anzick SL, Waters MR, ..., Nielsen R, Willerslev E
Nature 506 (7487) 225-229 [2014-02-13; online 2014-02-14]
Affiliated researcher
Thiamin function, metabolism, uptake, and transport.
Manzetti S, Zhang J, van der Spoel D
Biochemistry 53 (5) 821-835 [2014-02-11; online 2014-01-31]
Affiliated researcher
Structural and functional insights into peptidoglycan access for the lytic amidase LytA of Streptococcus pneumoniae.
Mellroth P, Sandalova T, Kikhney A, ..., Henriques-Normark B, Achour A
MBio 5 (1) e01120-e01113 [2014-02-11; online 2014-02-11]
Affiliated researcher
Separating endogenous ancient DNA from modern day contamination in a Siberian Neandertal.
Skoglund P, Northoff BH, Shunkov MV, ..., Krause J, Jakobsson M
Proc. Natl. Acad. Sci. U.S.A. 111 (6) 2229-2234 [2014-02-11; online 2014-01-27]
Affiliated researcher
Prognostic polypeptide blood plasma biomarkers of Alzheimer's disease progression.
Yang H, Lyutvinskiy Y, Herukka SK, ..., Rutishauser D, Zubarev RA
J. Alzheimers Dis. 40 (3) 659-666 [2014-02-08; online 2014-02-08]
Affiliated researcher
Fast and accurate database searches with MS-GF+Percolator.
Granholm V, Kim S, Navarro JC, ..., Smith RD, Käll L
J. Proteome Res. 13 (2) 890-897 [2014-02-07; online 2013-12-23]
Affiliated researcher
Variation in the MC4R gene is associated with bone phenotypes in elderly Swedish women.
Garg G, Kumar J, McGuigan FE, ..., Luthman H, Åkesson K
PLoS ONE 9 (2) e88565 [2014-02-06; online 2014-02-06]
Affiliated researcher
Visual detection of DNA on paper chips.
Song Y, Gyarmati P, Araújo AC, ..., Brumer H, Ståhl PL
Anal. Chem. 86 (3) 1575-1582 [2014-02-04; online 2014-01-17]
Affiliated researcher
Removal of total organic carbon from sewage wastewater using poly(ethylenimine)-functionalized magnetic nanoparticles.
Lakshmanan R, Sanchez-Dominguez M, Matutes-Aquino JA, Wennmalm S, Kuttuva Rajarao G
Langmuir 30 (4) 1036-1044 [2014-02-04; online 2014-01-24]
Affiliated researcher
Rhizaria.
Burki F, Keeling PJ
Curr. Biol. 24 (3) R103-R107 [2014-02-03; online 2014-02-08]
Fabien Burki SciLifeLab Fellow
Differentially expressed proteins in malignant and benign adrenocortical tumors.
Kjellin H, Johansson H, Höög A, ..., Jakobsson PJ, Kjellman M
PLoS ONE 9 (2) e87951 [2014-02-03; online 2014-02-03]
Affiliated researcher
The genome of Spironucleus salmonicida highlights a fish pathogen adapted to fluctuating environments.
Xu F, Jerlström-Hultqvist J, Einarsson E, ..., Svärd SG, Andersson JO
PLoS Genet 10 (2) e1004053 [2014-02-00; online 2014-02-06]
Affiliated researcher
Subtyping of gliomas of various WHO grades by the application of immunohistochemistry.
Popova SN, Bergqvist M, Dimberg A, ..., Sooman L, Alafuzoff I
Histopathology 64 (3) 365-379 [2014-02-00; online 2013-11-05]
Affiliated researcher
Evolutionary imprint of activation: The design principles of VSDs
Palovcak E, Delemotte L, Klein ML, Carnevale V
J Gen Physiol 143 (2) 145-156 [2014-02-00; online 2014-01-27]
Lucie Delemotte SciLifeLab Fellow
Endosymbiotic Gene Transfer in Tertiary Plastid-Containing Dinoflagellates
Burki F, Imanian B, Hehenberger E, ..., Maruyama S, Keeling PJ
Eukaryotic Cell 13 (2) 246-255 [2014-02-00; online 2013-12-02]
Fabien Burki SciLifeLab Fellow
Androgen levels during adjuvant endocrine therapy in postmenopausal breast cancer patients.
Baumgart J, Nilsson K, Stavreus Evers A, ..., Bergquist J, Sundström Poromaa I
Climacteric 17 (1) 48-54 [2014-02-00; online 2013-06-28]
Affiliated researcher
An efficient and extensible format, library, and API for binary trajectory data from molecular simulations.
Lundborg M, Apostolov R, Spångberg D, ..., van der Spoel D, Lindahl E
J Comput Chem 35 (3) 260-269 [2014-01-30; online 2013-11-20]
Affiliated researcher
Silencing motifs in the Clr2 protein from fission yeast, Schizosaccharomyces pombe.
Steinhauf D, Rodriguez A, Vlachakis D, ..., Bongcam-Rudloff E, Bjerling P
PLoS ONE 9 (1) e86948 [2014-01-27; online 2014-01-27]
Affiliated researcher
Host-specificity and dynamics in bacterial communities associated with Bloom-forming freshwater phytoplankton.
Bagatini IL, Eiler A, Bertilsson S, ..., Tessarolli LP, Vieira AA
PLoS ONE 9 (1) e85950 [2014-01-20; online 2014-01-20]
Affiliated researcher
Inefficient SRP interaction with a nascent chain triggers a mRNA quality control pathway.
Karamyshev AL, Patrick AE, Karamysheva ZN, ..., Johnson AE, Thomas PJ
Cell 156 (1-2) 146-157 [2014-01-16; online 2014-01-21]
Affiliated researcher
HSF1 at a glance.
Vihervaara A, Sistonen L
J. Cell. Sci. 127 (Pt 2) 261-266 [2014-01-15; online 2014-01-15]
Anniina Vihervaara SciLifeLab Fellow
Kinks, loops, and protein folding, with protein A as an example.
Krokhotin A, Liwo A, Maisuradze GG, Niemi AJ, Scheraga HA
J Chem Phys 140 (2) 025101 [2014-01-14; online 2014-01-21]
Affiliated researcher
High rates of gene flow by pollen and seed in oak populations across Europe.
Gerber S, Chadœuf J, Gugerli F, ..., Vendramin GG, Kremer A
PLoS ONE 9 (1) e85130 [2014-01-13; online 2014-01-13]
Affiliated researcher
Assessment of whole genome amplification for sequence capture and massively parallel sequencing.
Hasmats J, Gréen H, Orear C, ..., Käller M, Lundeberg J
PLoS ONE 9 (1) e84785 [2014-01-07; online 2014-01-07]
Affiliated researcher
Upper Palaeolithic Siberian genome reveals dual ancestry of Native Americans.
Raghavan M, Skoglund P, Graf KE, ..., Jakobsson M, Willerslev E
Nature 505 (7481) 87-91 [2014-01-02; online 2013-11-20]
Affiliated researcher
Dominant mutations in GRHL3 cause Van der Woude Syndrome and disrupt oral periderm development.
Peyrard-Janvid M, Leslie EJ, Kousa YA, ..., Kere J, Schutte BC
Am. J. Hum. Genet. 94 (1) 23-32 [2014-01-02; online 2013-12-19]
Affiliated researcher
The Database of Genomic Variants: a curated collection of structural variation in the human genome.
MacDonald JR, Ziman R, Yuen RK, Feuk L, Scherer SW
Nucleic Acids Res. 42 (Database issue) D986-D992 [2014-01-00; online 2013-10-29]
Affiliated researcher
Protein biomarkers in vernix with potential to predict the development of atopic eczema in early childhood.
Holm T, Rutishauser D, Kai-Larsen Y, ..., Alm J, Scheynius A
Allergy 69 (1) 104-112 [2014-01-00; online 2013-11-11]
Affiliated researcher
Plasma autoantibodies against apolipoprotein B-100 peptide 210 in subclinical atherosclerosis.
McLeod O, Silveira A, Fredrikson GN, ..., Nilsson J, Hamsten A
Atherosclerosis 232 (1) 242-248 [2014-01-00; online 2013-11-23]
Affiliated researcher
Pfam: the protein families database.
Finn RD, Bateman A, Clements J, ..., Tate J, Punta M
Nucleic Acids Res. 42 (Database issue) D222-D230 [2014-01-00; online 2013-11-27]
Affiliated researcher
Magnetic bead assisted labeling of antibodies at nanogram scale.
Dezfouli M, Vickovic S, Iglesias MJ, ..., Schwenk JM, Ahmadian A
Proteomics 14 (1) 14-18 [2014-01-00; online 2013-12-04]
Affiliated researcher Sanja Vickovic SciLifeLab Fellow
HiRIEF LC-MS enables deep proteome coverage and unbiased proteogenomics.
Branca RM, Orre LM, Johansson HJ, ..., Käll L, Lehtiö J
Nat. Methods 11 (1) 59-62 [2014-01-00; online 2013-11-17]
Affiliated researcher
FuseFISH: Robust Detection of Transcribed Gene Fusions in Single Cells
Semrau S, Crosetto N, Bienko M, ..., Chiarle R, van Oudenaarden A
Cell Reports 6 (1) 18-23 [2014-01-00; online 2014-01-00]
Magda Bienko SciLifeLab Fellow
FunCoup 3.0: database of genome-wide functional coupling networks.
Schmitt T, Ogris C, Sonnhammer EL
Nucleic Acids Res. 42 (Database issue) D380-D388 [2014-01-00; online 2013-10-31]
Affiliated researcher
Establishment and characterization of a primary and a metastatic melanoma cell line from Grey horses.
Seltenhammer MH, Sundström E, Meisslitzer-Ruppitsch C, ..., Vetterlein M, Golovko A
In Vitro Cell. Dev. Biol. Anim. 50 (1) 56-65 [2014-01-00; online 2013-08-28]
Affiliated researcher
Different mutations in PDE4D associated with developmental disorders with mirror phenotypes.
Lindstrand A, Grigelioniene G, Nilsson D, ..., Mäkitie O, Nordgren A
J. Med. Genet. 51 (1) 45-54 [2014-01-00; online 2013-11-07]
Affiliated researcher
BacMet: antibacterial biocide and metal resistance genes database.
Pal C, Bengtsson-Palme J, Rensing C, Kristiansson E, Larsson DG
Nucleic Acids Res. 42 (Database issue) D737-D743 [2014-01-00; online 2013-12-03]
DDLS Fellow Johan Bengtsson-Palme
A systematic analysis of commonly used antibodies in cancer diagnostics.
Gremel G, Bergman J, Djureinovic D, ..., Micke P, Pontén F
Histopathology 64 (2) 293-305 [2014-01-00; online 2013-11-05]
Affiliated researcher
Thermodynamics of hydronium and hydroxide surface solvation
Hub JS, Wolf MG, Caleman C, ..., Groenhof G, van der Spoel D
Chem Sci 5 (5) 1745 [2014-00-00; online 2014-00-00]
Affiliated researcher
Sensitive detection of C. parvum using near infrared emitting Ag2S@silica core–shell nanospheres
Srinivasan K, Thiruppathiraja C, Subramanian K, Dinakaran K
RSC Adv. 4 (107) 62399-62403 [2014-00-00; online 2014-00-00]
Affiliated researcher
Native and functionalized micrometre-sized cellulose capsules prepared by microfluidic flow focusing
Carrick C, Larsson PA, Brismar H, Aidun C, Wågberg L
RSC Adv. 4 (37) 19061-19067 [2014-00-00; online 2014-00-00]
Affiliated researcher
Metaxa, Overview
Bengtsson-Palme J, Hartmann M, Eriksson KM, Nilsson RH
Encyclopedia of Metagenomics - (-) 1-5 [2014-00-00; online 2014-04-16]
DDLS Fellow Johan Bengtsson-Palme

Publications 9.5.0