Jemth AS

Kinetic and structural characterization of NUDT15 and NUDT18 as catalysts of isoprene pyrophosphate hydrolysis.

Scaletti ER, Unterlass JE, Almlöf I, ..., Stenmark P, Jemth AS

FEBS J. 291 (19) 4301-4322 [2024-10-00; online 2024-06-29]

Kinetic and structural characterization of human NUDIX hydrolases NUDT15 and NUDT18 as catalysts of isoprene pyrophosphate hydrolysis

Scaletti ER, Unterlass JE, Almlöf I, ..., Stenmark P, Jemth AS

- - (-) - [2023-11-29; online 2023-11-29]

Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function.

Michel M, Benítez-Buelga C, Calvo PA, ..., de Vega M, Helleday T

Science (New York, N.Y.) 376 (6600) 1471-1476 [2022-06-24; online 2022-06-23]

Crystal structures of human PAICS reveal substrate and product binding of an emerging cancer target.

Škerlová J, Unterlass J, Göttmann M, ..., Jemth AS, Stenmark P

J Biol Chem 295 (33) 11656-11668 [2020-08-14; online 2020-06-22]

MutT homologue 1 (MTH1) removes N6-methyl-dATP from the dNTP pool.

Scaletti ER, Vallin KS, Bräutigam L, ..., Stenmark P, Jemth AS

J Biol Chem 295 (15) 4761-4772 [2020-04-10; online 2020-03-06]

MTH1 promotes mitotic progression to avoid oxidative DNA damage in cancer cells

Gad H, Mortusewicz O, Rudd SG, ..., Berglund UW, Helleday T

- - (-) - [2019-03-12; online 2019-03-12]