de Vega M

Nucleobase catalysts for the enzymatic activation of 8-oxoguanine DNA glycosylase 1.

Hank EC, D'Arcy-Evans ND, Scaletti ER, ..., Helleday T, Michel M

RSC Chem Biol 7 (1) 169-181 [2026-01-14; online 2025-10-28]

Giving an Enzyme Scissors: Serotonin Derivatives as Potent Organocatalytic Switches for DNA Repair Enzyme OGG1.

Varga M, Ortis F, Del Prado A, ..., Watson AJB, Michel M

J Med Chem 68 (21) 22455-22483 [2025-11-13; online 2025-10-15]

Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function.

Michel M, Benítez-Buelga C, Calvo PA, ..., de Vega M, Helleday T

Science (New York, N.Y.) 376 (6600) 1471-1476 [2022-06-24; online 2022-06-23]