Warpman Berglund U

Data from Inhibition of Oxidized Nucleotide Sanitation By TH1579 and Conventional Chemotherapy Cooperatively Enhance Oxidative DNA Damage and Survival in AML

Centio A, Estruch M, Reckzeh K, ..., Helleday T, Theilgaard-Mönch K

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Overexpressed c-Myc Sensitizes Cells to TH1579, a Mitotic Arrest and Oxidative DNA Damage Inducer.

Henriksson S, Calderón-Montaño JM, Solvie D, Warpman Berglund U, Helleday T

Biomolecules 12 (12) - [2022-11-29; online 2022-11-29]

Overexpressed C-Myc Sensitize Cells to TH1579, an Mitotic Arrest and Oxidative DNA Damage Inducer

Henriksson S, Calderón-Montaño JM, Solvie D, Warpman Berglund U, Helleday T

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Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function.

Michel M, Benítez-Buelga C, Calvo PA, ..., de Vega M, Helleday T

Science (New York, N.Y.) 376 (6600) 1471-1476 [2022-06-24; online 2022-06-23]

Inhibition of Oxidized Nucleotide Sanitation By TH1579 and Conventional Chemotherapy Cooperatively Enhance Oxidative DNA Damage and Survival in AML.

Centio A, Estruch M, Reckzeh K, ..., Helleday T, Theilgaard-Mönch K

Mol. Cancer Ther. 21 (5) 703-714 [2022-05-04; online 2022-03-06]

MTH1 Inhibitor TH1579 Induces Oxidative DNA Damage and Mitotic Arrest in Acute Myeloid Leukemia.

Sanjiv K, Calderón-Montaño JM, Pham TM, ..., Helleday T, Warpman Berglund U

Cancer Res. 81 (22) 5733-5744 [2021-11-15; online 2021-09-30]

Development of a chemical probe against NUDT15.

Zhang SM, Desroses M, Hagenkort A, ..., Stenmark P, Helleday T

Nat. Chem. Biol. 16 (10) 1120-1128 [2020-10-00; online 2020-07-20]

MTH1 Inhibitor TH588 Disturbs Mitotic Progression and Induces Mitosis-Dependent Accumulation of Genomic 8-oxodG.

Rudd SG, Gad H, Sanjiv K, ..., Berglund UW, Helleday T

Cancer Res. 80 (17) 3530-3541 [2020-09-01; online 2020-04-20]

AXL and CAV-1 play a role for MTH1 inhibitor TH1579 sensitivity in cutaneous malignant melanoma.

Das I, Gad H, Bräutigam L, ..., Egyházi Brage S, Warpman Berglund U

Cell Death Differ. 27 (7) 2081-2098 [2020-07-00; online 2020-01-09]

Karonudib is a promising anticancer therapy in hepatocellular carcinoma.

Hua X, Sanjiv K, Gad H, ..., Helleday T, Warpman Berglund U

Ther Adv Med Oncol 11 (-) 1758835919866960 [2019-08-23; online 2019-08-23]