Langenberg C

The genetic landscape of neuro-related proteins in human plasma.

Repetto L, Chen J, Yang Z, ..., Navarro P, Shen X

Nat Hum Behav 8 (11) 2222-2234 [2024-11-00; online 2024-08-29]

Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits.

Keaton JM, Kamali Z, Xie T, ..., Snieder H, Warren HR

Nat. Genet. 56 (5) 778-791 [2024-05-00; online 2024-04-30]

Author Correction: Elevated plasma complement factor H related 5 protein is associated with venous thromboembolism.

Iglesias MJ, Sanchez-Rivera L, Ibrahim-Kosta M, ..., Trégouët DA, Odeberg J

Nat Commun 14 (1) 7752 [2023-11-27; online 2023-11-27]

DDLS Fellow Fredrik Edfors

Large-scale exome array summary statistics resources for glycemic traits to aid effector gene prioritization.

Willems SM, Ng NHJ, Fernandez J, ..., Gloyn AL, Barroso I

Wellcome Open Res 8 (-) 483 [2023-10-20; online 2023-10-20]

GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification.

Lagou V, Jiang L, Ulrich A, ..., Prokopenko I, Meta-Analysis of Glucose and Insulin-Related Traits Consortium (MAGIC)

Nat. Genet. 55 (9) 1448-1461 [2023-09-00; online 2023-09-07]

Elevated plasma complement factor H related 5 protein is associated with venous thromboembolism.

Iglesias MJ, Sanchez-Rivera L, Ibrahim-Kosta M, ..., Trégouët DA, Odeberg J

Nat Commun 14 (1) 3280 [2023-06-07; online 2023-06-07]

DDLS Fellow Fredrik Edfors

Genome-wide analysis identifies genetic effects on reproductive success and ongoing natural selection at the FADS locus.

Mathieson I, Day FR, Barban N, ..., Mills MC, Perry JRB

Nat Hum Behav 7 (5) 790-801 [2023-05-00; online 2023-03-02]

An atlas of genetic scores to predict multi-omic traits.

Xu Y, Ritchie SC, Liang Y, ..., Butterworth AS, Inouye M

Nature 616 (7955) 123-131 [2023-04-00; online 2023-03-29]

Unraveling Neuro-Proteogenomic Landscape and Therapeutic Implications for Human Behaviors and Psychiatric Disorders.

Repetto L, Chen J, Yang Z, ..., Navarro P, Shen X

Res Sq - (-) - [2023-03-31; online 2023-03-31]

Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention.

Wang Z, Emmerich A, Pillon NJ, ..., Loos RJF, Hoed MD

Nat. Genet. 54 (9) 1332-1344 [2022-09-00; online 2022-09-07]

Genetic Landscape of the ACE2 Coronavirus Receptor.

Yang Z, Macdonald-Dunlop E, Chen J, ..., Wilson JF, Shen X

Circulation 145 (18) 1398-1411 [2022-05-03; online 2022-04-07]

Physical activity and sedentary behavior; mechanistic insights and role in disease prevention

Hoed Md, Wang Z, Emmerich A, ..., Thomis M, Loos R

- - (-) - [2021-12-16; online 2021-12-16]

Implicating genes, pleiotropy and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis

Kanoni S, Graham SE, Wang Y, ..., Assimes TL, Peloso GM

- - (-) - [2021-12-16; online 2021-12-16]

A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids

Ramdas S, Judd J, Graham SE, ..., Zhu X, Brown CD

- - (-) - [2021-12-08; online 2021-12-08]

The trans-ancestral genomic architecture of glycemic traits.

Chen J, Spracklen CN, Marenne G, ..., Barroso I, Meta-Analysis of Glucose and Insulin-related Traits Consortium (MAGIC)

Nat. Genet. 53 (6) 840-860 [2021-06-00; online 2021-05-31]

Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.

Lagou V, Mägi R, Hottenga JJ, ..., Prokopenko I, Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC)

Nat Commun 12 (1) 995 [2021-02-08; online 2021-02-08]

Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.

Lagou V, Mägi R, Hottenga JJ, ..., Prokopenko I, Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC)

Nat Commun 12 (1) 24 [2021-01-05; online 2021-01-05]

Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

Mahajan A, Spracklen CN, Zhang W, ..., McCarthy MI, Morris AP

- - (-) - [2020-09-23; online 2020-09-23]

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure.

Shah S, Henry A, Roselli C, ..., Swerdlow DI, Lumbers RT

Nat Commun 11 (1) 163 [2020-01-09; online 2020-01-09]

Associations of autozygosity with a broad range of human phenotypes.

Clark DW, Okada Y, Moore KHS, ..., Kubo M, Wilson JF

Nat Commun 10 (1) 4957 [2019-10-31; online 2019-10-31]

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.

Justice AE, Karaderi T, Highland HM, ..., T2D-Genes Consortium , MAGIC Investigators

Nat. Genet. 51 (3) 452-469 [2019-03-00; online 2019-02-18]

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.

Wheeler E, Leong A, Liu CT, ..., Barroso I, Meigs JB

PLoS Med. 14 (9) e1002383 [2017-09-00; online 2017-09-12]