Loos RJF

Family name	Loos
Given name	Ruth J F
Initials	RJF
ORCID	ORCID 0000-0002-8532-5087
Affiliations	The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Science, University of Copenhagen, Copenhagen, Denmark.

29 publications

PubMed DOI Crossref

Common genetic variants near SLC2A2 and glycemic response to glimepiride in the GRADE comparative effectiveness clinical trial.

Li JH, Szczerbinski L, Tripputi M, ..., Mercader JM, Florez JC

medRxiv - (-) - [2025-10-08; online 2025-10-08]

PubMed DOI Crossref

Precision nutrition for cardiometabolic diseases.

Guasch-Ferré M, Wittenbecher C, Palmnäs M, ..., Sargent JL, Merino J

Nat. Med. 31 (5) 1444-1453 [2025-05-00; online 2025-04-30]

Clemens Wittenbecher DDLS Fellow

PubMed DOI Crossref

Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits.

Keaton JM, Kamali Z, Xie T, ..., Snieder H, Warren HR

Nat. Genet. 56 (5) 778-791 [2024-05-00; online 2024-04-30]

PubMed DOI Crossref

Large-scale exome array summary statistics resources for glycemic traits to aid effector gene prioritization.

Willems SM, Ng NHJ, Fernandez J, ..., Gloyn AL, Barroso I

Wellcome Open Res 8 (-) 483 [2023-10-20; online 2023-10-20]

PubMed DOI Crossref

Precision medicine in complex diseases-Molecular subgrouping for improved prediction and treatment stratification.

Johansson Å, Andreassen OA, Brunak S, ..., Wheelock CE, Jacobsson B

J. Intern. Med. 294 (4) 378-396 [2023-10-00; online 2023-04-24]

PubMed DOI Crossref

Genetic insights into resting heart rate and its role in cardiovascular disease.

van de Vegte YJ, Eppinga RN, van der Ende MY, ..., Verweij N, van der Harst P

Nat Commun 14 (1) 4646 [2023-08-02; online 2023-08-02]

PubMed DOI Crossref

Author Correction: The power of genetic diversity in genome-wide association studies of lipids.

Graham SE, Clarke SL, Wu KH, ..., Sun YV, Willer CJ

Nature 618 (7965) E19-E20 [2023-06-00; online 2023-05-27]

PubMed DOI Crossref

Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention.

Wang Z, Emmerich A, Pillon NJ, ..., Loos RJF, Hoed MD

Nat. Genet. 54 (9) 1332-1344 [2022-09-00; online 2022-09-07]

PubMed DOI Crossref

Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential.

Nakao T, Bick AG, Taub MA, ..., NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium , Natarajan P

Sci Adv 8 (14) eabl6579 [2022-04-08; online 2022-04-06]

Abhishek Niroula DDLS Fellow

PubMed DOI Crossref

Dysregulation of macrophage PEPD in obesity determines adipose tissue fibro-inflammation and insulin resistance.

Pellegrinelli V, Rodriguez-Cuenca S, Rouault C, ..., Clément K, Vidal-Puig A

Nat Metab 4 (4) 476-494 [2022-04-00; online 2022-04-25]

Physical activity and sedentary behavior; mechanistic insights and role in disease prevention

Hoed Md, Wang Z, Emmerich A, ..., Thomis M, Loos R

- - (-) - [2021-12-16; online 2021-12-16]

PubMed DOI Crossref

The power of genetic diversity in genome-wide association studies of lipids.

Graham SE, Clarke SL, Wu KH, ..., Sun YV, Willer CJ

Nature 600 (7890) 675-679 [2021-12-00; online 2021-12-09]

PubMed DOI Crossref

Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.

Lagou V, Mägi R, Hottenga JJ, ..., Prokopenko I, Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC)

Nat Commun 12 (1) 995 [2021-02-08; online 2021-02-08]

PubMed DOI Crossref

Genome-wide discovery of genetic loci that uncouple excess adiposity from its comorbidities.

Huang LO, Rauch A, Mazzaferro E, ..., Kilpeläinen TO, Loos RJF

Nat Metab 3 (2) 228-243 [2021-02-00; online 2021-02-22]

PubMed DOI Crossref

Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.

Lagou V, Mägi R, Hottenga JJ, ..., Prokopenko I, Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC)

Nat Commun 12 (1) 24 [2021-01-05; online 2021-01-05]

Dysregulation of macrophage PEPD in obesity determines adipose tissue fibro-inflammation and insulin resistance

Pellegrinelli V, Rodriguez-Cuenca S, Rouault C, ..., Clément K, Vidal-Puig A

- - (-) - [2020-08-24; online 2020-08-24]

PubMed DOI Crossref

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction.

Ntalla I, Weng LC, Cartwright JH, ..., Lubitz SA, Munroe PB

Nat Commun 11 (1) 2542 [2020-05-21; online 2020-05-21]

PubMed DOI Crossref

Associations of autozygosity with a broad range of human phenotypes.

Clark DW, Okada Y, Moore KHS, ..., Kubo M, Wilson JF

Nat Commun 10 (1) 4957 [2019-10-31; online 2019-10-31]

PubMed DOI Crossref

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels.

Tin A, Marten J, Halperin Kuhns VL, ..., Vitart V, Köttgen A

Nat. Genet. 51 (10) 1459-1474 [2019-10-00; online 2019-10-02]

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 210 loci underlying cardiac conduction

Ntalla I, Weng LC, Cartwright JH, ..., Lubitz SA, Munroe PB

- - (-) - [2019-07-24; online 2019-07-24]

PubMed DOI Crossref

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

Turcot V, Lu Y, Highland HM, ..., Hirschhorn JN, Loos RJF

Nat. Genet. 51 (7) 1191-1192 [2019-07-00; online 2019-06-05]

PubMed DOI Crossref

A catalog of genetic loci associated with kidney function from analyses of a million individuals.

Wuttke M, Li Y, Li M, ..., Köttgen A, Pattaro C

Nat. Genet. 51 (6) 957-972 [2019-06-00; online 2019-05-31]

PubMed DOI Crossref

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.

Justice AE, Karaderi T, Highland HM, ..., T2D-Genes Consortium , MAGIC Investigators

Nat. Genet. 51 (3) 452-469 [2019-03-00; online 2019-02-18]

PubMed DOI Crossref

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.

Evangelou E, Warren HR, Mosen-Ansorena D, ..., Elliott P, Caulfield MJ

Nat. Genet. 50 (12) 1755 [2018-12-00; online 2018-11-16]

PubMed DOI Crossref

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.

Evangelou E, Warren HR, Mosen-Ansorena D, ..., Caulfield MJ, Million Veteran Program

Nat. Genet. 50 (10) 1412-1425 [2018-10-00; online 2018-09-17]

PubMed DOI Crossref

PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity.

van Setten J, Brody JA, Jamshidi Y, ..., Arking DE, Sotoodehnia N

Nat Commun 9 (1) 2904 [2018-07-25; online 2018-07-25]

PubMed DOI Crossref

Multi-ethnic genome-wide association study for atrial fibrillation.

Roselli C, Chaffin MD, Weng LC, ..., Lunetta KL, Ellinor PT

Nat. Genet. 50 (9) 1225-1233 [2018-06-11; online 2018-06-11]

PubMed DOI Crossref

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.

Flannick J, Fuchsberger C, Mahajan A, ..., Boehnke M, McCarthy MI

Sci Data 4 (-) 170179 [2017-12-19; online 2017-12-19]

PubMed DOI Crossref

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.

Winkler TW, Justice AE, Graff M, ..., Kutalik Z, Loos RJ

PLoS Genet 11 (10) e1005378 [2015-10-00; online 2015-10-01]

SciLifeLab Data Centre

Publications 9.5.1