Lambert NA

Pathway selectivity in Frizzleds is achieved by conserved micro-switches defining pathway-determining, active conformations.

Grätz L, Kowalski-Jahn M, Scharf MM, ..., Gloriam DE, Schulte G

Nat Commun 14 (1) 4573 [2023-07-29; online 2023-07-29]

A conserved molecular switch in Class F receptors regulates receptor activation and pathway selection.

Wright SC, Kozielewicz P, Kowalski-Jahn M, ..., Carlsson J, Schulte G

Nat Commun 10 (1) 667 [2019-02-08; online 2019-02-08]

Jens Carlsson SciLifeLab Fellow