Karsten S

Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function.

Michel M, Benítez-Buelga C, Calvo PA, ..., de Vega M, Helleday T

Science (New York, N.Y.) 376 (6600) 1471-1476 [2022-06-24; online 2022-06-23]

MutT Homolog 1 Inhibitor Karonudib Attenuates Autoimmune Hepatitis by Inhibiting DNA Repair in Activated T Cells.

Chen Y, Hua X, Huang B, ..., Helleday T, Ma X

Hepatol Commun 6 (5) 1016-1031 [2022-05-00; online 2021-12-10]

MTH1 as a target to alleviate T cell driven diseases by selective suppression of activated T cells.

Karsten S, Fiskesund R, Zhang XM, ..., Helleday T, Warpman Berglund U

Cell Death Differ. 29 (1) 246-261 [2022-01-00; online 2021-08-29]