Fagerholm U

Family name	Fagerholm
Given name	Urban
Initials	U
ORCID	ORCID 0000-0001-6300-359X
Affiliations	Prosilico AB, Huddinge, Sweden.

14 publications

DOI Crossref

Comparing Lipinskis Rule of 5 and Machine Learning Based Prediction of Fraction Absorbed for Assessing Oral Absorption in Humans

Fagerholm U, Hellberg S, Alvarsson J, Ekmefjord M, Spjuth O

- - (-) - [2024-08-23; online 2024-08-23]

DOI Crossref

Prediction of the Human Pharmacokinetics of 30 Modern Antibiotics Using the ANDROMEDA Software

Fagerholm U, Hellberg S, Alvarsson J, Spjuth O

- - (-) - [2023-03-29; online 2023-03-29]

DOI Crossref

Application of the ANDROMEDA Software for Prediction of the Human Pharmacokinetics of Modern Anticancer Drugs

Fagerholm U, Hellberg S, Alvarsson J, Spjuth O

- - (-) - [2023-03-21; online 2023-03-21]

PubMed DOI Crossref

In Silico Prediction of Human Clinical Pharmacokinetics with ANDROMEDA by Prosilico: Predictions for an Established Benchmarking Data Set, a Modern Small Drug Data Set, and a Comparison with Laboratory Methods.

Fagerholm U, Hellberg S, Alvarsson J, Spjuth O

Altern Lab Anim 51 (1) 39-54 [2023-01-00; online 2022-12-26]

DOI Crossref

Predicting the Influence of Fat Food Intake on the Absorption and Systemic Exposure of Small Drugs using ANDROMEDA by Prosilico Software

Fagerholm U, Hellberg S, Alvarsson J, Spjuth O

- - (-) - [2022-12-08; online 2022-12-08]

DOI Crossref

Predicting Gastrointestinal Absorption of Prodrugs and their Drugs with the ANDROMEDA by Prosilico Software

Fagerholm U, Hellberg S, Alvarsson J, Spjuth O

- - (-) - [2022-11-25; online 2022-11-25]

DOI Crossref

Validation of predicted conformal intervals for prediction of human clinical pharmacokinetics

Fagerholm U, Alvarsson J, Hellberg S, Spjuth O

- - (-) - [2022-11-13; online 2022-11-13]

DOI Crossref

ANDROMEDA by Prosilico Software Successfully Predicts Human Clinical Pharmacokinetics of 300 Drugs Out of Reach for In Vitro Methods

Fagerholm U, Hellberg S, Alvarsson J, Spjuth O

- - (-) - [2022-10-07; online 2022-10-07]

DOI Crossref

Prediction and Classification of the Uptake and Disposition of Antidepressants and New CNS-Active Drugs in the Human Brain using the ANDROMEDA by Prosilico Software and Brainavailability-Matrix

Fagerholm U, Hellberg S, Alvarsson J, Spjuth O

- - (-) - [2022-09-30; online 2022-09-30]

DOI Crossref

Prediction of Biopharmaceutical Characteristics of PROTACs using the ANDROMEDA by Prosilico Software

Fagerholm U, Hellberg S, Alvarsson J, Spjuth O

- - (-) - [2022-09-23; online 2022-09-23]

DOI Crossref

Using the ANDROMEDA by Prosilico Software for Prediction of the Human Pharmacokinetics of 4 Compounds of Natural Origin - Colistin, Curucumin, UCN-01 and Voclosporin

Fagerholm U, Hellberg S, Alvarsson J, Spjuth O

- - (-) - [2022-08-17; online 2022-08-17]

PubMed DOI Crossref

In silico predictions of the human pharmacokinetics/toxicokinetics of 65 chemicals from various classes using conformal prediction methodology.

Fagerholm U, Hellberg S, Alvarsson J, Spjuth O

Xenobiotica 52 (2) 113-118 [2022-02-00; online 2022-03-16]

PubMed DOI Crossref

In silico prediction of volume of distribution of drugs in man using conformal prediction performs on par with animal data-based models.

Fagerholm U, Hellberg S, Alvarsson J, Arvidsson McShane S, Spjuth O

Xenobiotica 51 (12) 1366-1371 [2021-12-00; online 2021-12-08]

PubMed DOI Crossref

Comparison between lab variability and in silico prediction errors for the unbound fraction of drugs in human plasma.

Fagerholm U, Spjuth O, Hellberg S

Xenobiotica 51 (10) 1095-1100 [2021-10-00; online 2021-08-13]