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Protective Non-neutralizing anti-N-terminal Domain mAb Maintains Fc-mediated Function against SARS-COV-2 Variants up to BA.2.86-JN.1 with Superfluous In Vivo Protection against JN.1 Due to Attenuated Virulence.

Izadi A, Godzwon M, Söderlund Strand A, ..., Ohlin M, Nordenfelt P

J. Immunol. 213 (5) 678-689 [2024-09-01; online 2024-07-17]

Mammalian cell display with automated oligo design and library assembly allows for rapid residue level conformational epitope mapping.

Thalén NB, Karlander M, Lundqvist M, ..., Ohlin M, Rockberg J

Commun Biol 7 (1) 805 [2024-07-03; online 2024-07-03]

Design, structure and plasma binding of ancestral β-CoV scaffold antigens.

Hueting D, Schriever K, Sun R, ..., Andréll J, Syrén PO

Nat Commun 14 (1) 6527 [2023-10-16; online 2023-10-16]

Protective non-neutralizing mAbs Ab94 and Ab81 retain high-affinity and potent Fc-mediated function against SARS-CoV-2 variants from Omicron to XBB1.5

Izadi A, Godzwon M, Ohlin M, Nordenfelt P

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Reply to Pandey: IgG3 allotypes, modulation of antigen binding by constant domain changes, and therapeutic applications of Fc engineering.

Izadi A, Bahnan W, Ohlin M, Nordenfelt P

Proc. Natl. Acad. Sci. U.S.A. 120 (22) e2306562120 [2023-05-30; online 2023-05-22]

Subclass-switched anti-spike IgG3 oligoclonal cocktails strongly enhance Fc-mediated opsonization.

Izadi A, Hailu A, Godzwon M, ..., Bahnan W, Nordenfelt P

Proc. Natl. Acad. Sci. U.S.A. 120 (15) e2217590120 [2023-04-11; online 2023-04-03]

Design, structure and plasma binding of ancestral β-CoV scaffold antigens

Syren PO, Hueting D, Schriever K, ..., Pan-Hammarstrom Q, Andrell J

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