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Hildebrandt F, Ankarklev J, Matuschewski K
Trends Parasitol. 39 (2) 80-82 [2023-02-00; online 2022-12-24]
The liver is a major entry point and gatekeeper for invasive pathogens. However, high-resolution, spatiotemporal transcriptomic analysis of host-pathogen interactions has remained challenging. Afriat et al. have deconvoluted Plasmodium berghei liver-stage maturation at an unprecedented scale and discovered molecular signatures of heterogeneity during pre-erythrocytic development of malarial parasites.
PubMed 36567188
DOI 10.1016/j.pt.2022.12.005
Crossref 10.1016/j.pt.2022.12.005
pii: S1471-4922(22)00310-5