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Doloczki S, Kern C, Holmberg KO, Swartling FJ, Streuff J, Dyrager C
Chemistry 29 (51) e202300864 [2023-09-12; online 2023-08-09]
The study of a fluorescent indolin-3-one derivative is reported that, as opposed to its previously described congeners, selectively undergoes photoactivated ring-opening in apolar solvents. The excited state involved in this photoisomerization was partially deactivated by the formation of singlet oxygen. Cell studies revealed lipid droplet accumulation and efficient light-induced cytotoxicity.
PubMed 37332083
DOI 10.1002/chem.202300864
Crossref 10.1002/chem.202300864