Vascular characterization reveals immunomodulatory targets for brain metastases.

Lugano R, Dimberg A

Cancer Cell 42 (3) 328-330 [2024-03-11; online 2024-02-15]

Brain metastases are clinically challenging due to the unique brain microenvironment. In this issue of Cancer Cell, Bejarano et al. use transcriptional profiling and data integration to shed light on the molecular and cellular composition of the vasculature in brain metastases, identifying CD276 as an immunomodulatory target for therapy.

PubMed 38366590

DOI 10.1016/j.ccell.2024.01.011

Crossref 10.1016/j.ccell.2024.01.011

pii: S1535-6108(24)00035-7


Publications 9.5.1