Molecular tools to monitor health and disease - and lucky coincidences.

Landegren U

Ups. J. Med. Sci. 127 (-) - [2022-10-10; online 2022-10-10]

Improved methods for molecular analyses are obviously central for medical research. I will describe herein our work developing tools to reveal molecular states in health and disease. I will recount how I got started in this endeavor, and how our early work characterizing genetic variation led onto high-throughput protein measurements and to techniques for imaging the distribution of proteins and their activity states in tissues. I will also describe a more recent technique to measure even exceedingly rare genetic variants in order to monitor recurrence of disease for tumor patients.

PubMed 36337275

DOI 10.48101/ujms.v127.8987

Crossref 10.48101/ujms.v127.8987

pmc: PMC9602189
pii: 8987


Publications 9.5.1