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Panas MD, Kedersha N, Schulte T, Branca RM, Ivanov P, Anderson P
J. Cell Biol. 218 (7) 2425-2432 [2019-07-01; online 2019-06-06]
Tourrière et al. (2013. J. Cell Biol. https://doi.org/10.1083/jcb.200212128) reported that G3BP1-S149 dephosphorylation promotes stress granule formation. We show that constructs used to establish this conclusion contain additional mutations causing these phenotypes, and that S149 phosphorylation status does not change upon stress.
PubMed 31171631
DOI 10.1083/jcb.201801214
Crossref 10.1083/jcb.201801214
pmc: PMC6605800
pii: jcb.201801214