{"entity": "researcher", "timestamp": "2026-08-22T08:30:13.277Z", "family": "Lee", "given": "Jun-Hoe", "initials": "JH", "orcid": "0000-0002-6331-3472", "affiliations": ["Department of Cell- and Molecular Biology, Science for Life Laboratory, Uppsala University, SE-75123, Uppsala, Sweden."], "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/researcher/f20577fa77f1449a8a2e1360bf7c4f6b.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/researcher/f20577fa77f1449a8a2e1360bf7c4f6b"}}, "publications": [{"entity": "publication", "iuid": "36e5a0fe599d4469883e7645206a4782", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/36e5a0fe599d4469883e7645206a4782.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/36e5a0fe599d4469883e7645206a4782"}}, "title": "Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.", "authors": [{"family": "Dombrowski", "given": "Nina", "initials": "N", "orcid": "0000-0003-1917-2577", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/4cf6f4f25d5f451fa9e7677c5a699df9.json"}}, {"family": "Williams", "given": "Tom A", "initials": "TA", "orcid": "0000-0003-1072-0223", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/e04da3526c024149866bf6f24edc2d64.json"}}, {"family": "Sun", "given": "Jiarui", "initials": "J"}, {"family": "Woodcroft", "given": "Benjamin J", "initials": "BJ", "orcid": "0000-0003-0670-7480", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/d9354f0e11d746e9ac16ca276a594963.json"}}, {"family": "Lee", "given": "Jun-Hoe", "initials": "JH", "orcid": "0000-0002-6331-3472", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/f20577fa77f1449a8a2e1360bf7c4f6b.json"}}, {"family": "Minh", "given": "Bui Quang", "initials": "BQ", "orcid": "0000-0002-5535-6560", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/e410aeb274c244cebec7c2aac20a4050.json"}}, {"family": "Rinke", "given": "Christian", "initials": "C", "orcid": "0000-0003-4632-1187", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/4b7aa7d810634210a9dfe2f13dc00032.json"}}, {"family": "Spang", "given": "Anja", "initials": "A", "orcid": "0000-0002-6518-8556", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/ee19a6765cb847caac5c440aeb15b509.json"}}], "type": "journal article", "published": "2020-08-07", "journal": {"title": "Nat Commun", "issn": "2041-1723", "volume": "11", "issue": "1", "pages": "3939", "issn-l": "2041-1723"}, "abstract": "The recently discovered DPANN archaea are a potentially deep-branching, monophyletic radiation of organisms with small cells and genomes. However, the monophyly and early emergence of the various DPANN clades and their role in life's evolution are debated. Here, we reconstructed and analysed genomes of an uncharacterized archaeal phylum (Candidatus Undinarchaeota), revealing that its members have small genomes and, while potentially being able to conserve energy through fermentation, likely depend on partner organisms for the acquisition of certain metabolites. Our phylogenomic analyses robustly place Undinarchaeota as an independent lineage between two highly supported 'DPANN' clans. Further, our analyses suggest that DPANN have exchanged core genes with their hosts, adding to the difficulty of placing DPANN in the tree of life. This pattern can be sufficiently dominant to allow identifying known symbiont-host clades based on routes of gene transfer. Together, our work provides insights into the origins and evolution of DPANN and their hosts.", "doi": "10.1038/s41467-020-17408-w", "pmid": "32770105", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC7414124"}, {"db": "pii", "key": "10.1038/s41467-020-17408-w"}], "notes": [], "created": "2026-08-21T11:48:36.355Z", "modified": "2026-08-21T11:48:36.511Z"}, {"entity": "publication", "iuid": "787afabeab7b405f8adc7616dc6768ac", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/787afabeab7b405f8adc7616dc6768ac.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/787afabeab7b405f8adc7616dc6768ac"}}, "title": "Molecular parallelism in fast-twitch muscle proteins in echolocating mammals.", "authors": [{"family": "Lee", "given": "Jun-Hoe", "initials": "JH", "orcid": "0000-0002-6331-3472", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/f20577fa77f1449a8a2e1360bf7c4f6b.json"}}, {"family": "Lewis", "given": "Kevin M", "initials": "KM"}, {"family": "Moural", "given": "Timothy W", "initials": "TW"}, {"family": "Kirilenko", "given": "Bogdan", "initials": "B"}, {"family": "Borgonovo", "given": "Barbara", "initials": "B"}, {"family": "Prange", "given": "Gisa", "initials": "G"}, {"family": "Koessl", "given": "Manfred", "initials": "M"}, {"family": "Huggenberger", "given": "Stefan", "initials": "S"}, {"family": "Kang", "given": "ChulHee", "initials": "C", "orcid": "0000-0002-0693-7860", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/f5d7b8c72e0c449c98892804f78444a4.json"}}, {"family": "Hiller", "given": "Michael", "initials": "M", "orcid": "0000-0003-3024-1449", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/1005d0d1f4264b46b1cfe214c7aca246.json"}}], "type": "journal article", "published": "2018-09-00", "journal": {"title": "Sci Adv", "issn": "2375-2548", "volume": "4", "issue": "9", "pages": "eaat9660", "issn-l": "2375-2548"}, "abstract": "Detecting associations between genomic changes and phenotypic differences is fundamental to understanding how phenotypes evolved. By systematically screening for parallel amino acid substitutions, we detected known as well as novel cases (Strc, Tecta, and Cabp2) of parallelism between echolocating bats and toothed whales in proteins that could contribute to high-frequency hearing adaptations. Our screen also showed that echolocating mammals exhibit an unusually high number of parallel substitutions in fast-twitch muscle fiber proteins. Both echolocating bats and toothed whales produce an extremely rapid call rate when homing in on their prey, which was shown in bats to be powered by specialized superfast muscles. We show that these genes with parallel substitutions (Casq1, Atp2a1, Myh2, and Myl1) are expressed in the superfast sound-producing muscle of bats. Furthermore, we found that the calcium storage protein calsequestrin 1 of the little brown bat and the bottlenose dolphin functionally converged in its ability to form calcium-sequestering polymers at lower calcium concentrations, which may contribute to rapid calcium transients required for superfast muscle physiology. The proteins that our genomic screen detected could be involved in the convergent evolution of vocalization in echolocating mammals by potentially contributing to both rapid Ca2+ transients and increased shortening velocities in superfast muscles.", "doi": "10.1126/sciadv.aat9660", "pmid": "30263960", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC6157964"}, {"db": "pii", "key": "aat9660"}], "notes": [], "created": "2026-08-21T12:22:14.828Z", "modified": "2026-08-21T12:22:14.928Z"}]}