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"https://publications-affiliated.scilifelab.se/researcher/29699b2527c145fd91d53ce77d3ba590.json"}}, {"family": "Quigley", "given": "David A", "initials": "DA", "orcid": "0000-0002-4726-1473", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/a7672a24a905407c8b5f9d1e28deea02.json"}}, {"family": "Gilbert", "given": "Luke A", "initials": "LA", "orcid": "0000-0001-5854-0825", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/cc47a939f85b4a668bb091d77e2e330c.json"}}, {"family": "Feng", "given": "Felix Y", "initials": "FY", "orcid": "0000-0002-0963-7687", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/c5af5c0e774941ac97890f17640a339e.json"}}, {"family": "Moran", "given": "Amy E", "initials": "AE", "orcid": "0000-0003-1952-7737", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/724dca05212a4607acb6151bc9884efe.json"}}], "type": "journal article", "published": "2025-03-03", "journal": {"title": "Cancer Discov", "issn": "2159-8290", "issn-l": "2159-8274", "volume": "15", "issue": "3", "pages": "481-494"}, "abstract": "Immunotherapy options for immune cold tumors, like prostate cancer, are limited. We show that AR downregulates MHCI expression/antigen presentation and that AR inhibition improves T-cell responses and tumor control. This suggests that treatments combining AR inhibitors and checkpoint blockade may improve tumor immune surveillance and antitumor immunity in patients.", "doi": "10.1158/2159-8290.CD-24-0559", "pmid": "39652470", "labels": {"Arian Lundberg": null, "DDLS Fellow": null}, "xrefs": [{"db": "pmc", "key": "PMC11873725"}, {"db": "pii", "key": "750492"}], "notes": [], "created": "2025-03-20T14:05:18.677Z", "modified": "2025-11-14T07:49:59.126Z"}]}