{"entity": "researcher", "timestamp": "2026-09-26T10:50:59.122Z", "family": "Botnen", "given": "Helene", "initials": "H", "orcid": "0009-0008-1027-0676", "affiliations": ["Department of Communicable Disease Control and Health Protection, Public Health Agency of Sweden, Solna, Sweden."], "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/researcher/db3daea2906b417ea9711fb265d69fe0.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/researcher/db3daea2906b417ea9711fb265d69fe0"}}, "publications": [{"entity": "publication", "iuid": "5337a44be73f498b8a344ca81cc3be3b", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/5337a44be73f498b8a344ca81cc3be3b.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/5337a44be73f498b8a344ca81cc3be3b"}}, "title": "Wastewater surveillance of SARS-CoV-2 from aircraft to citywide monitoring.", "authors": [{"family": "Perez-Zabaleta", "given": "Mariel", "initials": "M"}, {"family": "Berg", "given": "Carlo", "initials": "C", "orcid": "0000-0001-7815-1077", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/3b3513d1aca744b89e15d05dfc5498e7.json"}}, {"family": "Latorre-Margalef", "given": "Neus", "initials": "N"}, {"family": "Owusu-Agyeman", "given": "Isaac", "initials": "I"}, {"family": "Kiyar", "given": "Ayda", "initials": "A"}, {"family": "Botnen", "given": "Helene", "initials": "H", "orcid": "0009-0008-1027-0676", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/db3daea2906b417ea9711fb265d69fe0.json"}}, {"family": "Sch\u00f6nning", "given": "Caroline", "initials": "C"}, {"family": "Hugerth", "given": "Luisa W", "initials": "LW", "orcid": "0000-0001-5432-1764", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/246ed7b405dd4c3f9ec5e7ff9f1d3ade.json"}}, {"family": "Cetecioglu", "given": "Zeynep", "initials": "Z", "orcid": "0000-0002-8170-379X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/7cd2bf37c08b4c88a62e48130c066c61.json"}}], "type": "journal article", "published": "2025-06-02", "journal": {"title": "Nat Commun", "issn": "2041-1723", "volume": "16", "issue": "1", "pages": "5125", "issn-l": "2041-1723"}, "abstract": "Wastewater monitoring is highly efficient in SARS-CoV-2 surveillance for tracking virus spread through travel, surpassing traditional airport passenger testing. This study explored the links between SARS-CoV-2 contents and variants from aircraft to city, assessing the impact of detected variants from international travellers versus the local population. A total of 969 variants using next-generation sequencing (NGS) were examined to understand the links between-aircraft, Arlanda airport, wastewater treatment plants (WWTPs), and Stockholm city-and compared these to variants detected in Stockholm hospitals from January to May 2023. SARS-CoV-2 contents in WWTPs reflected local infection rates, requiring analysis from multiple plants for an accurate city-wide infection assessment. Variants initially detected in aircraft arriving from China did not spread widely during the study period. RT-qPCR is adequate for the detection of specific variants in wastewater, including Variants Under Monitoring. However, NGS remains a powerful method for identifying novel variants. Wastewater monitoring was more effective than clinical testing in the early detection of specific variants, with notable delays observed in clinical surveillance. Furthermore, a broad range of variants are detected in wastewater that surpasses clinical tests. This underscores the vital role of wastewater-based epidemiology in managing future outbreaks and enhancing global health security.", "doi": "10.1038/s41467-025-60490-1", "pmid": "40456842", "labels": {"DDLS Fellow": "", "Luisa Hugerth": ""}, "xrefs": [{"db": "pmc", "key": "PMC12130461"}, {"db": "pii", "key": "10.1038/s41467-025-60490-1"}], "notes": [], "created": "2026-09-23T09:09:28.911Z", "modified": "2026-09-23T09:09:29.084Z"}]}