{"entity": "researcher", "timestamp": "2026-08-20T20:49:08.142Z", "family": "Lyng\u00e5", "given": "Patrik", "initials": "P", "orcid": "0000-0002-5093-7358", "affiliations": ["Department of Clinical Science and Education, S\u00f6dersjukhuset, Sjukhusbacken 10, SE-118 83 Stockholm, Sweden.", "Department of Cardiology, Karolinska Institutet, S\u00f6dersjukhuset, Sjukhusbacken 10, SE-118 83 Stockholm, Sweden."], "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/researcher/d7f0055bcc8542b8a2cadd4d0706ec46.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/researcher/d7f0055bcc8542b8a2cadd4d0706ec46"}}, "publications": [{"entity": "publication", "iuid": "d51981f4ff6d47d888705b8b6a316b83", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/d51981f4ff6d47d888705b8b6a316b83.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/d51981f4ff6d47d888705b8b6a316b83"}}, "title": "Baseline characteristics and 1-year outcome by left ventricular function in the CABG PREFERS.", "authors": [{"family": "L\u00f6fstr\u00f6m", "given": "Ulrika", "initials": "U", "orcid": "0009-0009-3972-0172", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/82615d2ee1ef421eb50f64ef7eac2590.json"}}, {"family": "Linde", "given": "Cecilia", "initials": "C", "orcid": "0000-0002-9039-6023", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/c045c55e5e4541eeb1fcd7408041927f.json"}}, {"family": "Eriksson", "given": "Maria J", "initials": "MJ"}, {"family": "Maret", "given": "Eva", "initials": "E"}, {"family": "Corbascio", "given": "Matthias", "initials": "M"}, {"family": "Ekstr\u00f6m", "given": "Mattias", "initials": "M"}, {"family": "Lyng\u00e5", "given": "Patrik", "initials": "P", "orcid": "0000-0002-5093-7358", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/d7f0055bcc8542b8a2cadd4d0706ec46.json"}}, {"family": "Wall\u00e9n", "given": "H\u00e5kan", "initials": "H"}, {"family": "Persson", "given": "Bengt", "initials": "B"}, {"family": "Persson", "given": "Hans", "initials": "H"}, {"family": "Hage", "given": "Camilla", "initials": "C", "orcid": "0000-0002-4142-2416", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/c3801769a2924359ade1ffd30e46d879.json"}}], "type": "journal article", "published": "2025-03-00", "journal": {"title": "Eur Heart J Open", "issn": "2752-4191", "volume": "5", "issue": "2", "pages": "oeaf014", "issn-l": null}, "abstract": "The aim of this study is to describe patients undergoing elective coronary artery bypass grafting (CABG) surgery by left ventricular (LV) function at baseline and 1-year follow-up.\n\nIn the single-centre CABG PREFERS cohort prospective study, we classified patients planned for elective CABG by LV function assessed by echocardiography and N-terminal pro-B-type natriuretic peptide (NT-proBNP) into three phenotype groups: preserved ejection fraction (EF; pEF), reduced EF (rEF), and normal, irrespective of signs or symptoms of heart failure (HF). At baseline and 1-year follow-up, electrocardiogram, echocardiography, cardiac magnetic resonance imaging, laboratory tests, and quality of life were assessed. Sixty-one of a total of 136 patients (45%) had systolic and/or diastolic LV dysfunction (25% pEF, 20% rEF, and the rest 55% none: the normal group). Median EF was 59% (pEF), 40% (rEF), and 59% (normal). Most patients had multivessel coronary artery disease without left main stem stenosis (60%). At 1-year follow-up, some improvements in echo parameters were seen in pEF and rEF. But in the normal group compared to baseline, there were deteriorations in the following: E/\u00e9: 7.8-8.9, P < 0.001; NT-proBNP 150-182 ng/L, P = 0.015; and estimated glomerular filtration rate (eGFR) 82.5-78.9 mL/min/1.73 m\u00b2, P = 0.003. During a median follow-up time of 2.9 years, eight patients (5.8%) died and eight (5.8%) were hospitalized for HF.\n\nIn patients undergoing elective CABG, signs of LV dysfunction were common and found in 45%. Patients with normal LV function showed signs of worsening systolic and diastolic LV function, eGFR, and NT-pro-BNP at 1-year follow-up.\n\nClinicaltrials.gov identifier: NCT03671122.", "doi": "10.1093/ehjopen/oeaf014", "pmid": "40177505", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC11962374"}, {"db": "pii", "key": "oeaf014"}, {"db": "ClinicalTrials.gov", "key": "NCT03671122"}], "notes": [], "created": "2026-08-20T09:40:41.236Z", "modified": "2026-08-20T09:40:41.434Z"}, {"entity": "publication", "iuid": "346c37e20f45410c8f71d825e8c17504", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/346c37e20f45410c8f71d825e8c17504.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/346c37e20f45410c8f71d825e8c17504"}}, "title": "Deteriorated mechanics of left ventricular diastolic filling one year after coronary artery bypass grafting", "authors": [{"family": "Norderfeldt", "given": "Joakim", "initials": "J", "orcid": "0000-0002-1425-1674", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/c8df67065aab41fbacf12efee41f6d6b.json"}}, {"family": "Sundqvist", "given": "Martin G", "initials": "MG", "orcid": "0000-0003-0934-761X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/adcf228fc6044ec0849f68054786d499.json"}}, {"family": "Maret", "given": "Eva", "initials": "E", "orcid": "0000-0003-2281-8340", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/6bdaabc2d4e644c3b2b284720dde560b.json"}}, {"family": "L\u00f6fstr\u00f6m", "given": "Ulrika", "initials": "U", "orcid": "0009-0009-3972-0172", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/82615d2ee1ef421eb50f64ef7eac2590.json"}}, {"family": "Corbascio", "given": "Matthias", "initials": "M", "orcid": "0000-0003-3544-6689", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/9328417812e44e8b8314dd53d3e51ae5.json"}}, {"family": "Hage", "given": "Camilla", "initials": "C", "orcid": "0000-0002-4142-2416", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/c3801769a2924359ade1ffd30e46d879.json"}}, {"family": "Ekstr\u00f6m", "given": "Mattias", "initials": "M", "orcid": "0000-0001-9448-8403", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/f405f60211aa40b589cbf154f1bae9f9.json"}}, {"family": "Wall\u00e9n", "given": "H\u00e5kan", "initials": "H"}, {"family": "Lyng\u00e5", "given": "Patrik", "initials": "P", "orcid": "0000-0002-5093-7358", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/d7f0055bcc8542b8a2cadd4d0706ec46.json"}}, {"family": "Persson", "given": "Bengt", "initials": "B"}, {"family": "Persson", "given": "Hans E", "initials": "HE", "orcid": "0000-0001-6329-8295", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/041c83f77f6b4dc7bafa85d3f684fc70.json"}}, {"family": "Linde", "given": "Cecilia", "initials": "C", "orcid": "0000-0002-9039-6023", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/c045c55e5e4541eeb1fcd7408041927f.json"}}, {"family": "Marlevi", "given": "David", "initials": "D", "orcid": "0000-0003-1002-2070", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b976ea76c522430c9483513e474b83df.json"}}, {"family": "Eriksson", "given": "Maria J", "initials": "MJ", "orcid": "0000-0003-3233-2862", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/ca91b20ea167492782df045b75372caa.json"}}, {"family": "Ugander", "given": "Martin", "initials": "M", "orcid": "0000-0003-3665-2038", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/a7f431bebb934e41824c2ea2b7f04d60.json"}}], "type": "posted-content", "published": "2024-11-29", "journal": {"issn-l": null}, "abstract": null, "doi": "10.1101/2024.11.28.24318125", "pmid": null, "labels": [], "xrefs": [], "notes": [], "created": "2026-08-20T10:59:17.356Z", "modified": "2026-08-20T10:59:17.766Z"}]}