{"entity": "researcher", "timestamp": "2026-08-20T20:50:15.852Z", "family": "Thomas", "given": "Rachael", "initials": "R", "orcid": "0000-0002-3029-8798", "affiliations": [], "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/researcher/d7613e07c9b242748a912e2ab73a5542.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/researcher/d7613e07c9b242748a912e2ab73a5542"}}, "publications": [{"entity": "publication", "iuid": "9b6c299c3be9475c925b30a7b62e0588", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/9b6c299c3be9475c925b30a7b62e0588.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/9b6c299c3be9475c925b30a7b62e0588"}}, "title": "Data from Genomically Complex Human Angiosarcoma and Canine Hemangiosarcoma Establish Convergent Angiogenic Transcriptional Programs Driven by Novel Gene Fusions", "authors": [{"family": "Kim", "given": "Jong Hyuk", "initials": "JH", "orcid": "0000-0002-1645-0036", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/3553b69d2420463ca6a24d52696a7da7.json"}}, {"family": "Megquier", "given": "Kate", "initials": "K", "orcid": "0000-0002-1458-0865", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/d84d6a467fac40d5a926885732eca967.json"}}, {"family": "Thomas", "given": "Rachael", "initials": "R", "orcid": "0000-0002-3029-8798", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/d7613e07c9b242748a912e2ab73a5542.json"}}, {"family": "Sarver", "given": "Aaron L", "initials": "AL"}, {"family": "Song", "given": "Jung Min", "initials": "JM"}, {"family": "Kim", "given": "Yoon Tae", "initials": "YT"}, {"family": "Cheng", "given": "Nuojin", "initials": "N"}, {"family": "Schulte", "given": "Ashley J", "initials": "AJ"}, {"family": "Linden", "given": "Michael A", "initials": "MA"}, {"family": "Murugan", "given": "Paari", "initials": "P", "orcid": "0000-0003-4706-213X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b6bf0a99d52e4f5abed4fad7da3c8e02.json"}}, {"family": "Oseth", "given": "LeAnn", "initials": "L"}, {"family": "Forster", "given": "Colleen L", "initials": "CL"}, {"family": "Elvers", "given": "Ingegerd", "initials": "I"}, {"family": "Swofford", "given": "Ross", "initials": "R", "orcid": "0000-0003-3676-8479", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/85b0174c633b417b933092763175bb1c.json"}}, {"family": "Turner-Maier", "given": "Jason", "initials": "J"}, {"family": "Karlsson", "given": "Elinor K", "initials": "EK", "orcid": "0000-0002-4343-3776", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/81b5c82fcb904394b6a6b1d811863fa0.json"}}, {"family": "Breen", "given": "Matthew", "initials": "M"}, {"family": "Lindblad-Toh", "given": "Kerstin", "initials": "K"}, {"family": "Modiano", "given": "Jaime F", "initials": "JF", "orcid": "0000-0001-6398-7648", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/7ba4bb579a21472dab716ebf61874801.json"}}], "type": "posted-content", "published": "2023-04-03", "journal": {"issn-l": null}, "abstract": null, "doi": "10.1158/1541-7786.c.6545168.v1", "pmid": null, "labels": [], "xrefs": [], "notes": [], "created": "2026-08-20T12:14:04.142Z", "modified": "2026-08-20T12:14:04.329Z"}, {"entity": "publication", "iuid": "0d6c57232f734850b20ccda3e909d4ad", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/0d6c57232f734850b20ccda3e909d4ad.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/0d6c57232f734850b20ccda3e909d4ad"}}, "title": "Data from <i>SETD2</i> Is Recurrently Mutated in Whole-Exome Sequenced Canine Osteosarcoma", "authors": [{"family": "Sakthikumar", "given": "Sharadha", "initials": "S"}, {"family": "Elvers", "given": "Ingegerd", "initials": "I"}, {"family": "Kim", "given": "Jaegil", "initials": "J"}, {"family": "Arendt", "given": "Maja L", "initials": "ML"}, {"family": "Thomas", "given": "Rachael", "initials": "R", "orcid": "0000-0002-3029-8798", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/d7613e07c9b242748a912e2ab73a5542.json"}}, {"family": "Turner-Maier", "given": "Jason", "initials": "J"}, {"family": "Swofford", "given": "Ross", "initials": "R"}, {"family": "Johnson", "given": "Jeremy", "initials": "J"}, {"family": "Schumacher", "given": "Steven E", "initials": "SE"}, {"family": "Alf\u00f6ldi", "given": "Jessica", "initials": "J"}, {"family": "Axelsson", "given": "Erik", "initials": "E"}, {"family": "Couto", "given": "C Guillermo", "initials": "CG"}, {"family": "Kisseberth", "given": "William C", "initials": "WC"}, {"family": "Pettersson", "given": "Mats E", "initials": "ME"}, {"family": "Getz", "given": "Gad", "initials": "G"}, {"family": "Meadows", "given": "Jennifer R S", "initials": "JRS", "orcid": "0000-0002-0850-230X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/9f363e8d74594ffeb0d68aa6d774b242.json"}}, {"family": "Modiano", "given": "Jaime F", "initials": "JF"}, {"family": "Breen", "given": "Matthew", "initials": "M"}, {"family": "Kierczak", "given": "Marcin", "initials": "M"}, {"family": "Forsberg-Nilsson", "given": "Karin", "initials": "K"}, {"family": "Marinescu", "given": "Voichita D", "initials": "VD"}, {"family": "Lindblad-Toh", "given": "Kerstin", "initials": "K"}], "type": "posted-content", "published": "2023-03-31", "journal": {"issn-l": null}, "abstract": null, "doi": "10.1158/0008-5472.c.6510633", "pmid": null, "labels": [], "xrefs": [], "notes": [], "created": "2026-08-20T12:03:29.875Z", "modified": "2026-08-20T12:03:29.975Z"}, {"entity": "publication", "iuid": "f7270a6b130547a1b1ff831ee95f58f7", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/f7270a6b130547a1b1ff831ee95f58f7.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/f7270a6b130547a1b1ff831ee95f58f7"}}, "title": "Data from <i>SETD2</i> Is Recurrently Mutated in Whole-Exome Sequenced Canine Osteosarcoma", "authors": [{"family": "Sakthikumar", "given": "Sharadha", "initials": "S"}, {"family": "Elvers", "given": "Ingegerd", "initials": "I"}, {"family": "Kim", "given": "Jaegil", "initials": "J"}, {"family": "Arendt", "given": "Maja L", "initials": "ML"}, {"family": "Thomas", "given": "Rachael", "initials": "R", "orcid": "0000-0002-3029-8798", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/d7613e07c9b242748a912e2ab73a5542.json"}}, {"family": "Turner-Maier", "given": "Jason", "initials": "J"}, {"family": "Swofford", "given": "Ross", "initials": "R"}, {"family": "Johnson", "given": "Jeremy", "initials": "J"}, {"family": "Schumacher", "given": "Steven E", "initials": "SE"}, {"family": "Alf\u00f6ldi", "given": "Jessica", "initials": "J"}, {"family": "Axelsson", "given": "Erik", "initials": "E"}, {"family": "Couto", "given": "C Guillermo", "initials": "CG"}, {"family": "Kisseberth", "given": "William C", "initials": "WC"}, {"family": "Pettersson", "given": "Mats E", "initials": "ME"}, {"family": "Getz", "given": "Gad", "initials": "G"}, {"family": "Meadows", "given": "Jennifer R S", "initials": "JRS", "orcid": "0000-0002-0850-230X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/9f363e8d74594ffeb0d68aa6d774b242.json"}}, {"family": "Modiano", "given": "Jaime F", "initials": "JF"}, {"family": "Breen", "given": "Matthew", "initials": "M"}, {"family": "Kierczak", "given": "Marcin", "initials": "M"}, {"family": "Forsberg-Nilsson", "given": "Karin", "initials": "K"}, {"family": "Marinescu", "given": "Voichita D", "initials": "VD"}, {"family": "Lindblad-Toh", "given": "Kerstin", "initials": "K"}], "type": "posted-content", "published": "2023-03-31", "journal": {"issn-l": null}, "abstract": null, "doi": "10.1158/0008-5472.c.6510633.v1", "pmid": null, "labels": [], "xrefs": [], "notes": [], "created": "2026-08-20T12:10:26.411Z", "modified": "2026-08-20T12:10:26.430Z"}, {"entity": "publication", "iuid": "d05f4aeea1d543a6818bf3faaf86357e", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/d05f4aeea1d543a6818bf3faaf86357e.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/d05f4aeea1d543a6818bf3faaf86357e"}}, "title": "Genomically Complex Human Angiosarcoma and Canine Hemangiosarcoma Establish Convergent Angiogenic Transcriptional Programs Driven by Novel Gene Fusions.", "authors": [{"family": "Kim", "given": "Jong Hyuk", "initials": "JH", "orcid": "0000-0002-1645-0036", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/3553b69d2420463ca6a24d52696a7da7.json"}}, {"family": "Megquier", "given": "Kate", "initials": "K", "orcid": "0000-0002-1458-0865", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/d84d6a467fac40d5a926885732eca967.json"}}, {"family": "Thomas", "given": "Rachael", "initials": "R", "orcid": "0000-0002-3029-8798", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/d7613e07c9b242748a912e2ab73a5542.json"}}, {"family": "Sarver", "given": "Aaron L", "initials": "AL"}, {"family": "Song", "given": "Jung Min", "initials": "JM"}, {"family": "Kim", "given": "Yoon Tae", "initials": "YT"}, {"family": "Cheng", "given": "Nuojin", "initials": "N"}, {"family": "Schulte", "given": "Ashley J", "initials": "AJ"}, {"family": "Linden", "given": "Michael A", "initials": "MA"}, {"family": "Murugan", "given": "Paari", "initials": "P", "orcid": "0000-0003-4706-213X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b6bf0a99d52e4f5abed4fad7da3c8e02.json"}}, {"family": "Oseth", "given": "LeAnn", "initials": "L"}, {"family": "Forster", "given": "Colleen L", "initials": "CL"}, {"family": "Elvers", "given": "Ingegerd", "initials": "I"}, {"family": "Swofford", "given": "Ross", "initials": "R", "orcid": "0000-0003-3676-8479", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/85b0174c633b417b933092763175bb1c.json"}}, {"family": "Turner-Maier", "given": "Jason", "initials": "J"}, {"family": "Karlsson", "given": "Elinor K", "initials": "EK", "orcid": "0000-0002-4343-3776", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/81b5c82fcb904394b6a6b1d811863fa0.json"}}, {"family": "Breen", "given": "Matthew", "initials": "M"}, {"family": "Lindblad-Toh", "given": "Kerstin", "initials": "K"}, {"family": "Modiano", "given": "Jaime F", "initials": "JF", "orcid": "0000-0001-6398-7648", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/7ba4bb579a21472dab716ebf61874801.json"}}], "type": "journal article", "published": "2021-05-00", "journal": {"title": "Mol. Cancer Res.", "issn": "1557-3125", "volume": "19", "issue": "5", "pages": "847-861", "issn-l": "1541-7786"}, "abstract": "Sporadic angiosarcomas are aggressive vascular sarcomas whose rarity and genomic complexity present significant obstacles in deciphering the pathogenic significance of individual genetic alterations. Numerous fusion genes have been identified across multiple types of cancers, but their existence and significance remain unclear in sporadic angiosarcomas. In this study, we leveraged RNA-sequencing data from 13 human angiosarcomas and 76 spontaneous canine hemangiosarcomas to identify fusion genes associated with spontaneous vascular malignancies. Ten novel protein-coding fusion genes, including TEX2-PECAM1 and ATP8A2-FLT1, were identified in seven of the 13 human tumors, with two tumors showing mutations of TP53. HRAS and NRAS mutations were found in angiosarcomas without fusions or TP53 mutations. We found 15 novel protein-coding fusion genes including MYO16-PTK2, GABRA3-FLT1, and AKT3-XPNPEP1 in 11 of the 76 canine hemangiosarcomas; these fusion genes were seen exclusively in tumors of the angiogenic molecular subtype that contained recurrent mutations in TP53, PIK3CA, PIK3R1, and NRAS. In particular, fusion genes and mutations of TP53 cooccurred in tumors with higher frequency than expected by random chance, and they enriched gene signatures predicting activation of angiogenic pathways. Comparative transcriptomic analysis of human angiosarcomas and canine hemangiosarcomas identified shared molecular signatures associated with activation of PI3K/AKT/mTOR pathways. Our data suggest that genome instability induced by TP53 mutations might create a predisposition for fusion events that may contribute to tumor progression by promoting selection and/or enhancing fitness through activation of convergent angiogenic pathways in this vascular malignancy. IMPLICATIONS: This study shows that, while drive events of malignant vasoformative tumors of humans and dogs include diverse mutations and stochastic rearrangements that create novel fusion genes, convergent transcriptional programs govern the highly conserved morphologic organization and biological behavior of these tumors in both species.", "doi": "10.1158/1541-7786.MCR-20-0937", "pmid": "33649193", "labels": [], "xrefs": [{"db": "mid", "key": "NIHMS1675846"}, {"db": "pmc", "key": "PMC8137578"}, {"db": "pii", "key": "1541-7786.MCR-20-0937"}], "notes": [], "created": "2026-08-20T12:14:23.333Z", "modified": "2026-08-20T12:14:23.423Z"}, {"entity": "publication", "iuid": "d365ac0a2fe941bbb47a27b146d888b1", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/d365ac0a2fe941bbb47a27b146d888b1.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/d365ac0a2fe941bbb47a27b146d888b1"}}, "title": "Comparative Genomics Reveals Shared Mutational Landscape in Canine Hemangiosarcoma and Human Angiosarcoma.", "authors": [{"family": "Megquier", "given": "Kate", "initials": "K", "orcid": "0000-0002-1458-0865", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/d84d6a467fac40d5a926885732eca967.json"}}, {"family": "Turner-Maier", "given": "Jason", "initials": "J"}, {"family": "Swofford", "given": "Ross", "initials": "R"}, {"family": "Kim", "given": "Jong-Hyuk", "initials": "JH", "orcid": "0000-0002-1645-0036", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/3553b69d2420463ca6a24d52696a7da7.json"}}, {"family": "Sarver", "given": "Aaron L", "initials": "AL"}, {"family": "Wang", "given": "Chao", "initials": "C"}, {"family": "Sakthikumar", "given": "Sharadha", "initials": "S", "orcid": "0000-0002-7746-8264", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/38967e663cdc4351ae2c0c090ab8c39e.json"}}, {"family": "Johnson", "given": "Jeremy", "initials": "J"}, {"family": "Koltookian", "given": "Michele", "initials": "M"}, {"family": "Lewellen", "given": "Mitzi", "initials": "M"}, {"family": "Scott", "given": "Milcah C", "initials": "MC"}, {"family": "Schulte", "given": "Ashley J", "initials": "AJ"}, {"family": "Borst", "given": "Luke", "initials": "L"}, {"family": "Tonomura", "given": "Noriko", "initials": "N"}, {"family": "Alfoldi", "given": "Jessica", "initials": "J"}, {"family": "Painter", "given": "Corrie", "initials": "C"}, {"family": "Thomas", "given": "Rachael", "initials": "R", "orcid": "0000-0002-3029-8798", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/d7613e07c9b242748a912e2ab73a5542.json"}}, {"family": "Karlsson", "given": "Elinor K", "initials": "EK", "orcid": "0000-0002-4343-3776", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/81b5c82fcb904394b6a6b1d811863fa0.json"}}, {"family": "Breen", "given": "Matthew", "initials": "M"}, {"family": "Modiano", "given": "Jaime F", "initials": "JF", "orcid": "0000-0001-6398-7648", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/7ba4bb579a21472dab716ebf61874801.json"}}, {"family": "Elvers", "given": "Ingegerd", "initials": "I"}, {"family": "Lindblad-Toh", "given": "Kerstin", "initials": "K"}], "type": "journal article", "published": "2019-12-00", "journal": {"title": "Mol. Cancer Res.", "issn": "1557-3125", "volume": "17", "issue": "12", "pages": "2410-2421", "issn-l": "1541-7786"}, "abstract": "Angiosarcoma is a highly aggressive cancer of blood vessel-forming cells with few effective treatment options and high patient mortality. It is both rare and heterogenous, making large, well-powered genomic studies nearly impossible. Dogs commonly suffer from a similar cancer, called hemangiosarcoma, with breeds like the golden retriever carrying heritable genetic factors that put them at high risk. If the clinical similarity of canine hemangiosarcoma and human angiosarcoma reflects shared genomic etiology, dogs could be a critically needed model for advancing angiosarcoma research. We assessed the genomic landscape of canine hemangiosarcoma via whole-exome sequencing (47 golden retriever hemangiosarcomas) and RNA sequencing (74 hemangiosarcomas from multiple breeds). Somatic coding mutations occurred most frequently in the tumor suppressor TP53 (59.6% of cases) as well as two genes in the PI3K pathway: the oncogene PIK3CA (29.8%) and its regulatory subunit PIK3R1 (8.5%). The predominant mutational signature was the age-associated deamination of cytosine to thymine. As reported in human angiosarcoma, CDKN2A/B was recurrently deleted and VEGFA, KDR, and KIT recurrently gained. We compared the canine data to human data recently released by The Angiosarcoma Project, and found many of the same genes and pathways significantly enriched for somatic mutations, particularly in breast and visceral angiosarcomas. Canine hemangiosarcoma closely models the genomic landscape of human angiosarcoma of the breast and viscera, and is a powerful tool for investigating the pathogenesis of this devastating disease. IMPLICATIONS: We characterize the genomic landscape of canine hemangiosarcoma and demonstrate its similarity to human angiosarcoma.", "doi": "10.1158/1541-7786.MCR-19-0221", "pmid": "31570656", "labels": [], "xrefs": [{"db": "mid", "key": "NIHMS1540746"}, {"db": "pmc", "key": "PMC7067513"}, {"db": "pii", "key": "1541-7786.MCR-19-0221"}], "notes": [], "created": "2026-08-20T12:14:09.684Z", "modified": "2026-08-20T12:14:09.813Z"}, {"entity": "publication", "iuid": "56f3be882400460986acb3afc127902e", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/56f3be882400460986acb3afc127902e.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/56f3be882400460986acb3afc127902e"}}, "title": "SETD2 Is Recurrently Mutated in Whole-Exome Sequenced Canine Osteosarcoma.", "authors": [{"family": "Sakthikumar", "given": "Sharadha", "initials": "S"}, {"family": "Elvers", "given": "Ingegerd", "initials": "I"}, {"family": "Kim", "given": "Jaegil", "initials": "J"}, {"family": "Arendt", "given": "Maja L", "initials": "ML"}, {"family": "Thomas", "given": "Rachael", "initials": "R", "orcid": "0000-0002-3029-8798", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/d7613e07c9b242748a912e2ab73a5542.json"}}, {"family": "Turner-Maier", "given": "Jason", "initials": "J"}, {"family": "Swofford", "given": "Ross", "initials": "R"}, {"family": "Johnson", "given": "Jeremy", "initials": "J"}, {"family": "Schumacher", "given": "Steven E", "initials": "SE"}, {"family": "Alf\u00f6ldi", "given": "Jessica", "initials": "J"}, {"family": "Axelsson", "given": "Erik", "initials": "E"}, {"family": "Couto", "given": "C Guillermo", "initials": "CG"}, {"family": "Kisseberth", "given": "William C", "initials": "WC"}, {"family": "Pettersson", "given": "Mats E", "initials": "ME"}, {"family": "Getz", "given": "Gad", "initials": "G"}, {"family": "Meadows", "given": "Jennifer R S", "initials": "JRS", "orcid": "0000-0002-0850-230X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/9f363e8d74594ffeb0d68aa6d774b242.json"}}, {"family": "Modiano", "given": "Jaime F", "initials": "JF"}, {"family": "Breen", "given": "Matthew", "initials": "M"}, {"family": "Kierczak", "given": "Marcin", "initials": "M"}, {"family": "Forsberg-Nilsson", "given": "Karin", "initials": "K"}, {"family": "Marinescu", "given": "Voichita D", "initials": "VD"}, {"family": "Lindblad-Toh", "given": "Kerstin", "initials": "K"}], "type": "journal article", "published": "2018-07-01", "journal": {"title": "Cancer Res.", "issn": "1538-7445", "volume": "78", "issue": "13", "pages": "3421-3431", "issn-l": "0008-5472"}, "abstract": "Osteosarcoma is a debilitating bone cancer that affects humans, especially children and adolescents. A homologous form of osteosarcoma spontaneously occurs in dogs, and its differential incidence observed across breeds allows for the investigation of tumor mutations in the context of multiple genetic backgrounds. Using whole-exome sequencing and dogs from three susceptible breeds (22 golden retrievers, 21 Rottweilers, and 23 greyhounds), we found that osteosarcoma tumors show a high frequency of somatic copy-number alterations (SCNA), affecting key oncogenes and tumor-suppressor genes. The across-breed results are similar to what has been observed for human osteosarcoma, but the disease frequency and somatic mutation counts vary in the three breeds. For all breeds, three mutational signatures (one of which has not been previously reported) and 11 significantly mutated genes were identified. TP53 was the most frequently altered gene (83% of dogs have either mutations or SCNA in TP53), recapitulating observations in human osteosarcoma. The second most frequently mutated gene, histone methyltransferase SETD2, has known roles in multiple cancers, but has not previously been strongly implicated in osteosarcoma. This study points to the likely importance of histone modifications in osteosarcoma and highlights the strong genetic similarities between human and dog osteosarcoma, suggesting that canine osteosarcoma may serve as an excellent model for developing treatment strategies in both species.Significance: Canine osteosarcoma genomics identify SETD2 as a possible oncogenic driver of osteosarcoma, and findings establish the canine model as a useful comparative model for the corresponding human disease. Cancer Res; 78(13); 3421-31. \u00a92018 AACR.", "doi": "10.1158/0008-5472.CAN-17-3558", "pmid": "29724721", "labels": {"Affiliated researcher": null}, "xrefs": [{"db": "pii", "key": "0008-5472.CAN-17-3558"}], "notes": [], "created": "2019-01-17T13:52:33.893Z", "modified": "2026-08-20T12:10:44.996Z"}]}