{"entity": "researcher", "timestamp": "2026-08-29T04:16:10.582Z", "family": "Rindsj\u00f6", "given": "Erika", "initials": "E", "orcid": "0000-0001-9963-3243", "affiliations": ["Department of Laboratory Medicine, Division of Pathology, Section of Perinatal Pathology, Karolinska Institutet and Karolinska University Hospital Huddinge, Stockholm, Sweden.", "Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden."], "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/researcher/d6a6b79846ee4cf3ad7fb8c2a014e2ec.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/researcher/d6a6b79846ee4cf3ad7fb8c2a014e2ec"}}, "publications": [{"entity": "publication", "iuid": "496d2d7fe95d4d529230b2c9208556e1", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/496d2d7fe95d4d529230b2c9208556e1.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/496d2d7fe95d4d529230b2c9208556e1"}}, "title": "Placental inflammation, lifestyle, maternal and early child sensitisation to allergens - the assessment of lifestyle and allergic disease during infancy birth cohort.", "authors": [{"family": "Papadogiannakis", "given": "Nikos", "initials": "N"}, {"family": "Joerink", "given": "Maaike", "initials": "M"}, {"family": "Rindsj\u00f6", "given": "Erika", "initials": "E", "orcid": "0000-0001-9963-3243", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/d6a6b79846ee4cf3ad7fb8c2a014e2ec.json"}}, {"family": "Scheynius", "given": "Annika", "initials": "A"}, {"family": "Alm", "given": "Johan", "initials": "J"}], "type": "journal article", "published": "2019-05-00", "journal": {"title": "Acta Paediatr", "issn": "1651-2227", "volume": "108", "issue": "5", "pages": "927-932", "issn-l": null}, "abstract": "To investigate (i) whether maternal sensitisation to allergens, and lifestyle can influence the risk of acute and chronic inflammation of the placenta, in the forms of chorioamnionitis and villitis, respectively, and (ii) whether these placental inflammations are associated with the outcome of sensitisation for the child during preschool age.\n\nPlacentas from term uncomplicated pregnancies (n = 275) in the assessment of lifestyle and allergic disease during infancy study were analysed for the presence of acute chorioamnionitis and chronic villitis. Stepwise logistic regression was performed to estimate the relative risk of placental inflammation in relation to maternal allergic sensitisation and lifestyle, and the association between placental inflammation and sensitisation of the child up to five years of age.\n\nParity and delivery at home were independently associated with chorioamnionitis, home delivery only with the low grade. Maternal allergic sensitisation was associated with increased risk of villitis in the bivariable model, however, not in the multivariable model. No significant associations were detected between placental inflammation and the outcome of sensitisation to allergens at five years of age.\n\nOur data do not support the hypothesis that the increased risk for sensitisation of a child when the mother is allergic is mediated via placental inflammation.", "doi": "10.1111/apa.14618", "pmid": "30338564", "labels": [], "xrefs": [], "notes": [], "created": "2026-08-21T12:17:06.169Z", "modified": "2026-08-21T12:17:06.246Z"}]}