{"entity": "researcher", "timestamp": "2026-09-23T14:43:01.344Z", "family": "Ryman", "given": "Nils", "initials": "N", "orcid": "0000-0003-3342-8479", "affiliations": ["Division of Population Genetics Department of Zoology Stockholm University Stockholm Sweden."], "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/researcher/ce90ead3a9814f96be154ca7bbf6dcef.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/researcher/ce90ead3a9814f96be154ca7bbf6dcef"}}, "publications": [{"entity": "publication", "iuid": "6739398e96f84aafad1323ebe489d33b", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/6739398e96f84aafad1323ebe489d33b.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/6739398e96f84aafad1323ebe489d33b"}}, "title": "Monitoring genome-wide diversity over contemporary time with new indicators applied to Arctic charr populations", "authors": [{"family": "Saha", "given": "Atal", "initials": "A", "orcid": "0000-0003-1334-928X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/426576a1e5294833b030d98677b2594a.json"}}, {"family": "Kurland", "given": "Sara", "initials": "S", "orcid": "0000-0002-5370-1236", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/5cac912971b04f868a64af23e24cd5d0.json"}}, {"family": "Kutschera", "given": "Verena E", "initials": "VE", "orcid": "0000-0002-8930-534X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/c7185df2f7d44872960d604e9c70c551.json"}}, {"family": "D\u00edez-del-Molino", "given": "David", "initials": "D", "orcid": "0000-0002-9701-5940", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/ffd5992faedc45e1bfe19fd498485400.json"}}, {"family": "Ekman", "given": "Diana", "initials": "D"}, {"family": "Ryman", "given": "Nils", "initials": "N", "orcid": "0000-0003-3342-8479", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/ce90ead3a9814f96be154ca7bbf6dcef.json"}}, {"family": "Laikre", "given": "Linda", "initials": "L", "orcid": "0000-0001-9286-3361", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/1c0754b748c94ea7ab46fee02ca139c5.json"}}], "type": "journal-article", "published": "2024-04-00", "journal": {"title": "Conserv Genet", "issn": "1566-0621", "volume": "25", "issue": "2", "pages": "513-531", "issn-l": null}, "abstract": null, "doi": "10.1007/s10592-023-01586-3", "pmid": null, "labels": [], "xrefs": [], "notes": [], "created": "2026-09-23T11:27:20.508Z", "modified": "2026-09-23T11:27:20.620Z"}, {"entity": "publication", "iuid": "d0b9b1fa649741f39cef453e1fbc1c6d", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/d0b9b1fa649741f39cef453e1fbc1c6d.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/d0b9b1fa649741f39cef453e1fbc1c6d"}}, "title": "Genomic dynamics of brown trout populations released to a novel environment.", "authors": [{"family": "Kurland", "given": "Sara", "initials": "S", "orcid": "0000-0002-5370-1236", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/5cac912971b04f868a64af23e24cd5d0.json"}}, {"family": "Rafati", "given": "Nima", "initials": "N", "orcid": "0000-0002-3687-9745", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/0210ddd9d2c74696ae194924182e09d7.json"}}, {"family": "Ryman", "given": "Nils", "initials": "N", "orcid": "0000-0003-3342-8479", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/ce90ead3a9814f96be154ca7bbf6dcef.json"}}, {"family": "Laikre", "given": "Linda", "initials": "L", "orcid": "0000-0001-9286-3361", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/1c0754b748c94ea7ab46fee02ca139c5.json"}}], "type": "journal article", "published": "2022-07-00", "journal": {"title": "Ecol Evol", "issn": "2045-7758", "volume": "12", "issue": "7", "pages": "e9050", "issn-l": "2045-7758"}, "abstract": "Population translocations occur for a variety of reasons, from displacement due to climate change to human-induced transfers. Such actions have adverse effects on genetic variation and understanding their microevolutionary consequences requires monitoring. Here, we return to an experimental release of brown trout (Salmo trutta) in order to monitor the genomic effects of population translocations. In 1979, fish from each of two genetically (F ST = 0.16) and ecologically separate populations were simultaneously released, at one point in time, to a lake system previously void of brown trout. Here, whole-genome sequencing of pooled DNA (Pool-seq) is used to characterize diversity within and divergence between the introduced populations and fish inhabiting two lakes downstream of the release sites, sampled 30 years later (c. 5 generations). Present results suggest that while extensive hybridization has occurred, the two introduced populations are unequally represented in the lakes downstream of the release sites. One population, which is ecologically resident in its original habitat, mainly contributes to the lake closest to the release site. The other population, migratory in its natal habitat, is genetically more represented in the lake further downstream. Genomic regions putatively under directional selection in the new habitat are identified, where allele frequencies in both established populations are more similar to the introduced population stemming from a resident population than the migratory one. Results suggest that the microevolutionary consequences of population translocations, for example, hybridization and adaptation, can be rapid and that Pool-seq can be used as an initial tool to monitor genome-wide effects.", "doi": "10.1002/ece3.9050", "pmid": "35813906", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC9251865"}, {"db": "pii", "key": "ECE39050"}], "notes": [], "created": "2026-09-23T13:09:43.147Z", "modified": "2026-09-23T13:09:43.185Z"}, {"entity": "publication", "iuid": "77b8b0fe4aaf41b2a4f72e1fb935b969", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/77b8b0fe4aaf41b2a4f72e1fb935b969.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/77b8b0fe4aaf41b2a4f72e1fb935b969"}}, "title": "Whole-genome resequencing confirms reproductive isolation between sympatric demes of brown trout (Salmo trutta) detected with allozymes.", "authors": [{"family": "Saha", "given": "Atal", "initials": "A", "orcid": "0000-0003-1334-928X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/426576a1e5294833b030d98677b2594a.json"}}, {"family": "Andersson", "given": "Anastasia", "initials": "A", "orcid": "0000-0002-5698-4948", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/8ec66b48446d40b2bfb1a8f02feb2126.json"}}, {"family": "Kurland", "given": "Sara", "initials": "S", "orcid": "0000-0002-5370-1236", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/5cac912971b04f868a64af23e24cd5d0.json"}}, {"family": "Keehnen", "given": "Naomi L P", "initials": "NLP", "orcid": "0000-0002-8782-3477", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/fdc642ac7fe6414d809b4dda9742fce3.json"}}, {"family": "Kutschera", "given": "Verena E", "initials": "VE", "orcid": "0000-0002-8930-534X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/c7185df2f7d44872960d604e9c70c551.json"}}, {"family": "H\u00f6ssjer", "given": "Ola", "initials": "O", "orcid": "0000-0003-2767-8818", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b738df43c3b348bb8821f5c0bb1f46f7.json"}}, {"family": "Ekman", "given": "Diana", "initials": "D"}, {"family": "Karlsson", "given": "Sten", "initials": "S"}, {"family": "Kardos", "given": "Marty", "initials": "M"}, {"family": "St\u00e5hl", "given": "Gunnar", "initials": "G"}, {"family": "Allendorf", "given": "Fred W", "initials": "FW", "orcid": "0000-0003-3663-6425", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/032e5bc9b8d74ede82306ee9a64a0268.json"}}, {"family": "Ryman", "given": "Nils", "initials": "N", "orcid": "0000-0003-3342-8479", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/ce90ead3a9814f96be154ca7bbf6dcef.json"}}, {"family": "Laikre", "given": "Linda", "initials": "L", "orcid": "0000-0001-9286-3361", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/1c0754b748c94ea7ab46fee02ca139c5.json"}}], "type": "journal article", "published": "2022-01-00", "journal": {"title": "Mol. Ecol.", "issn": "1365-294X", "volume": "31", "issue": "2", "pages": "498-511", "issn-l": "0962-1083"}, "abstract": "The sympatric existence of genetically distinguishable populations of the same species remains a puzzle in ecology. Coexisting salmonid fish populations are known from over 100 freshwater lakes. Most studies of sympatric populations have used limited numbers of genetic markers making it unclear if genetic divergence involves certain parts of the genome. We returned to the first reported case of salmonid sympatry, initially detected through contrasting homozygosity at a single allozyme locus (coding for lactate dehydrogenase A) in brown trout in the small Lakes Bunnersj\u00f6arna, Sweden. First, we verified the existence of the two coexisting demes using a 96-SNP fluidigm array. We then applied whole-genome resequencing of pooled DNA to explore genome-wide diversity within and between these demes; nucleotide diversity was higher in deme I than in deme II. Strong genetic divergence is observed with genome-wide FST \u2248 0.2. Compared with data from populations of similar small lakes, this divergence is of similar magnitude as that between reproductively isolated populations. Individual whole-genome resequencing of two individuals per deme suggests higher inbreeding in deme II versus deme I, indicating different degree of isolation. We located two gene-copies for LDH-A and found divergence between demes in a regulatory section of one of these genes. However, we did not find a perfect fit between the sequence data and previous allozyme results, and this will require further research. Our data demonstrates genome-wide divergence governed mostly by genetic drift but also by diversifying selection in coexisting populations. This type of hidden biodiversity needs consideration in conservation management.", "doi": "10.1111/mec.16252", "pmid": "34699656", "labels": [], "xrefs": [{"db": "RefSeq", "key": "GCA_901001165.1"}], "notes": [], "created": "2026-09-23T11:03:15.498Z", "modified": "2026-09-23T11:03:15.831Z"}, {"entity": "publication", "iuid": "a476e5ac8d9c4412a40bb3af696f8f14", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/a476e5ac8d9c4412a40bb3af696f8f14.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/a476e5ac8d9c4412a40bb3af696f8f14"}}, "title": "Whole-genome resequencing confirms reproductive isolation between sympatric demes of brown trout (Salmo trutta) detected with allozymes", "authors": [{"family": "Saha", "given": "Atal", "initials": "A", "orcid": "0000-0003-1334-928X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/426576a1e5294833b030d98677b2594a.json"}}, {"family": "Andersson", "given": "Anastasia", "initials": "A"}, {"family": "Kurland", "given": "Sara", "initials": "S"}, {"family": "Keehnen", "given": "Naomi", "initials": "N"}, {"family": "Kutschera", "given": "Verena Esther", "initials": "VE"}, {"family": "Ekman", "given": "Diana", "initials": "D"}, {"family": "Karlsson", "given": "Sten", "initials": "S"}, {"family": "Kardos", "given": "Marty", "initials": "M"}, {"family": "H\u00f6ssjer", "given": "Ola", "initials": "O"}, {"family": "St\u00e5hl", "given": "Gunnar", "initials": "G"}, {"family": "Allendorf", "given": "Fred", "initials": "F", "orcid": "0000-0003-3663-6425", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/032e5bc9b8d74ede82306ee9a64a0268.json"}}, {"family": "Ryman", "given": "Nils", "initials": "N", "orcid": "0000-0003-3342-8479", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/ce90ead3a9814f96be154ca7bbf6dcef.json"}}, {"family": "Laikre", "given": "Linda", "initials": "L", "orcid": "0000-0001-9286-3361", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/1c0754b748c94ea7ab46fee02ca139c5.json"}}], "type": "posted-content", "published": "2021-01-11", "journal": {"issn-l": null}, "abstract": null, "doi": "10.22541/au.161035029.98155231/v1", "pmid": null, "labels": [], "xrefs": [], "notes": [], "created": "2026-09-23T14:31:28.130Z", "modified": "2026-09-23T14:31:28.214Z"}, {"entity": "publication", "iuid": "c57957d4415a488596762a209f41a216", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/c57957d4415a488596762a209f41a216.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/c57957d4415a488596762a209f41a216"}}, "title": "Exploring a Pool-seq-only approach for gaining population genomic insights in nonmodel species.", "authors": [{"family": "Kurland", "given": "Sara", "initials": "S", "orcid": "0000-0002-5370-1236", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/5cac912971b04f868a64af23e24cd5d0.json"}}, {"family": "Wheat", "given": "Christopher W", "initials": "CW"}, {"family": "de la Paz Celorio Mancera", "given": "Maria", "initials": "M", "orcid": "0000-0003-0296-0577", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/309ef007cfc249e69905c8b23b05bc03.json"}}, {"family": "Kutschera", "given": "Verena E", "initials": "VE", "orcid": "0000-0002-8930-534X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/c7185df2f7d44872960d604e9c70c551.json"}}, {"family": "Hill", "given": "Jason", "initials": "J"}, {"family": "Andersson", "given": "Anastasia", "initials": "A"}, {"family": "Rubin", "given": "Carl-Johan", "initials": "CJ"}, {"family": "Andersson", "given": "Leif", "initials": "L", "orcid": "0000-0002-4085-6968", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/7c8202937eda401fa0d07f583589359d.json"}}, {"family": "Ryman", "given": "Nils", "initials": "N", "orcid": "0000-0003-3342-8479", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/ce90ead3a9814f96be154ca7bbf6dcef.json"}}, {"family": "Laikre", "given": "Linda", "initials": "L", "orcid": "0000-0001-9286-3361", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/1c0754b748c94ea7ab46fee02ca139c5.json"}}], "type": "journal article", "published": "2019-10-00", "journal": {"title": "Ecol Evol", "issn": "2045-7758", "volume": "9", "issue": "19", "pages": "11448-11463", "issn-l": "2045-7758"}, "abstract": "Developing genomic insights is challenging in nonmodel species for which resources are often scarce and prohibitively costly. Here, we explore the potential of a recently established approach using Pool-seq data to generate a de novo genome assembly for mining exons, upon which Pool-seq data are used to estimate population divergence and diversity. We do this for two pairs of sympatric populations of brown trout (Salmo trutta): one naturally sympatric set of populations and another pair of populations introduced to a common environment. We validate our approach by comparing the results to those from markers previously used to describe the populations (allozymes and individual-based single nucleotide polymorphisms [SNPs]) and from mapping the Pool-seq data to a reference genome of the closely related Atlantic salmon (Salmo salar). We find that genomic differentiation (F ST) between the two introduced populations exceeds that of the naturally sympatric populations (F ST = 0.13 and 0.03 between the introduced and the naturally sympatric populations, respectively), in concordance with estimates from the previously used SNPs. The same level of population divergence is found for the two genome assemblies, but estimates of average nucleotide diversity differ ( \u2248 0.002 and \u03c0 \u00af \u2248 0.001 when mapping to \u03c0 \u00afS. trutta and S. salar, respectively), although the relationships between population values are largely consistent. This discrepancy might be attributed to biases when mapping to a haploid condensed assembly made of highly fragmented read data compared to using a high-quality reference assembly from a divergent species. We conclude that the Pool-seq-only approach can be suitable for detecting and quantifying genome-wide population differentiation, and for comparing genomic diversity in populations of nonmodel species where reference genomes are lacking.", "doi": "10.1002/ece3.5646", "pmid": "31641485", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC6802065"}, {"db": "pii", "key": "ECE35646"}, {"db": "Dryad", "key": "10.5061/dryad.q1h4k0n"}], "notes": [], "created": "2026-09-23T09:28:07.216Z", "modified": "2026-09-23T09:28:07.448Z"}]}