{"entity": "researcher", "timestamp": "2026-08-20T21:19:55.380Z", "family": "Capella-Gutierrez", "given": "Salvador", "initials": "S", "orcid": "0000-0002-0309-604X", "affiliations": ["Barcelona Supercomputing Centre (BSC), Barcelona, Spain."], "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/researcher/c76a6ff4986b42f58a0be702993eef42.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/researcher/c76a6ff4986b42f58a0be702993eef42"}}, "publications": [{"entity": "publication", "iuid": "5e29e009d86b4cb781d38abaee53167a", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/5e29e009d86b4cb781d38abaee53167a.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/5e29e009d86b4cb781d38abaee53167a"}}, "title": "New developments for the Quest for Orthologs benchmark service.", "authors": [{"family": "Altenhoff", "given": "Adrian", "initials": "A"}, {"family": "Nevers", "given": "Yannis", "initials": "Y", "orcid": "0000-0002-8604-2943", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/7e5e2aea9cc2433c880a3d650d4d0d5b.json"}}, {"family": "Tran", "given": "Vinh", "initials": "V"}, {"family": "Jyothi", "given": "Dushyanth", "initials": "D"}, {"family": "Martin", "given": "Maria", "initials": "M"}, {"family": "Cosentino", "given": "Salvatore", "initials": "S"}, {"family": "Majidian", "given": "Sina", "initials": "S", "orcid": "0000-0001-5345-6982", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/a14f17e8c2dc470dae5250c36d32cb27.json"}}, {"family": "Marcet-Houben", "given": "Marina", "initials": "M"}, {"family": "Fuentes-Palacios", "given": "Diego", "initials": "D"}, {"family": "Persson", "given": "Emma", "initials": "E"}, {"family": "Walsh", "given": "Thomas", "initials": "T"}, {"family": "Lecompte", "given": "Odile", "initials": "O"}, {"family": "Gabald\u00f3n", "given": "Toni", "initials": "T"}, {"family": "Kelly", "given": "Steven", "initials": "S"}, {"family": "Hu", "given": "Yanhui", "initials": "Y", "orcid": "0000-0003-1494-1402", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/d048ac84bf934c9d87774c6cab7430c6.json"}}, {"family": "Iwasaki", "given": "Wataru", "initials": "W"}, {"family": "Capella-Gutierrez", "given": "Salvador", "initials": "S", "orcid": "0000-0002-0309-604X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/c76a6ff4986b42f58a0be702993eef42.json"}}, {"family": "Dessimoz", "given": "Christophe", "initials": "C", "orcid": "0000-0002-2170-853X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/8d9dc970f3da45a4a46ecfdf4ab0893f.json"}}, {"family": "Thomas", "given": "Paul D", "initials": "PD", "orcid": "0000-0002-9074-3507", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/4af1f8a10ced487196829d162e22d314.json"}}, {"family": "Ebersberger", "given": "Ingo", "initials": "I", "orcid": "0000-0001-8187-9253", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/946c40da21e441d196dd8b88ea126df0.json"}}, {"family": "Sonnhammer", "given": "Erik", "initials": "E", "orcid": "0000-0002-9015-5588", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/8c4fb5f5a50a4dbb91bbea3cc6861ffa.json"}}], "type": "journal article", "published": "2024-12-00", "journal": {"title": "NAR Genomics and Bioinformatics", "issn": "2631-9268", "volume": "6", "issue": "4", "pages": "lqae167", "issn-l": null}, "abstract": "The Quest for Orthologs (QfO) orthology benchmark service (https://orthology.benchmarkservice.org) hosts a wide range of standardized benchmarks for orthology inference evaluation. It is supported and maintained by the QfO consortium, and is used to gather ortholog predictions and to examine strengths and weaknesses of newly developed and existing orthology inference methods. The web server allows different inference methods to be compared in a standardized way using the same proteome data. The benchmark results are useful for developing new methods and can help researchers to guide their choice of orthology method for applications in comparative genomics and phylogenetic analysis. We here present a new release of the Orthology Benchmark Service with a new benchmark based on feature architecture similarity as well as updated reference proteomes. We further provide a meta-analysis of the public predictions from 18 different orthology assignment methods to reveal how they relate in terms of ortholog predictions and benchmark performance. These results can guide users of orthologs to the best suited method for their purpose.", "doi": "10.1093/nargab/lqae167", "pmid": "39664814", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC11632614"}, {"db": "pii", "key": "lqae167"}], "notes": [], "created": "2026-08-20T09:43:00.453Z", "modified": "2026-08-20T09:43:00.602Z"}, {"entity": "publication", "iuid": "1bccc890845d45b7a227e7ac98ac8a0e", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/1bccc890845d45b7a227e7ac98ac8a0e.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/1bccc890845d45b7a227e7ac98ac8a0e"}}, "title": "Community-driven ELIXIR activities in single-cell omics", "authors": [{"family": "Czarnewski", "given": "Paulo", "initials": "P", "orcid": "0000-0001-8150-4021", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/501677a1262c438aa4077b205bb39a72.json"}}, {"family": "Mahfouz", "given": "Ahmed", "initials": "A", 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{"family": "Szomolay", "given": "Barbara", "initials": "B"}, {"family": "Videm", "given": "Pavankumar", "initials": "P", "orcid": "0000-0002-5192-126X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/6d1ca3572e2a48ae8da637fb437853a7.json"}}, {"family": "Hotz", "given": "Hans Rudolf", "initials": "HR", "orcid": "0000-0002-2799-424X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/18bfbd6dad26494b800a0f5547e867a0.json"}}, {"family": "Papatheodorou", "given": "Irene", "initials": "I", "orcid": "0000-0001-7270-5470", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/1875a08cb9cc435fb55b88d846d70cb2.json"}}, {"family": "Hancock", "given": "John M", "initials": "JM"}, {"family": "Gr\u00fcning", "given": "Bj\u00f6rn", "initials": "B", "orcid": "0000-0002-3079-6586", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b2539c92f7e2437782cf04c0c9a23fc8.json"}}, {"family": "Haerty", "given": "Wilfried", "initials": "W"}, {"family": "Krause", "given": "Roland", "initials": "R", "orcid": "0000-0001-9938-7126", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/ce39b6a8ab614d989c38b1731bd2f613.json"}}, {"family": "Capella-Gutierrez", "given": "Salvador", "initials": "S", "orcid": "0000-0002-0309-604X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/c76a6ff4986b42f58a0be702993eef42.json"}}, {"family": "Lesko\u0161ek", "given": "Brane", "initials": "B"}, {"family": "Alessandri", "given": "Luca", "initials": "L"}, {"family": "Arigoni", "given": "Maddalena", "initials": "M"}, {"family": "Rezen", "given": "Tadeja", "initials": "T"}, {"family": "Botzki", "given": "Alexander", "initials": "A", "orcid": "0000-0001-6691-4233", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/8fa68e29c93f4ac590c075d2d74ae829.json"}}, {"family": "Ferk", "given": "Polonca", "initials": "P"}, {"family": "Lindvall", "given": "Jessica", "initials": "J"}, {"family": "Heil", "given": "Katharina F", "initials": "KF", "orcid": "0000-0003-3341-3736", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/6e4f6f6e63c84436a18db5f749eb1bce.json"}}, {"family": "Ishaque", "given": "Naveed", "initials": "N", "orcid": "0000-0002-8426-901X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b4d61d936b2d419d84f072808b4c09f2.json"}}, {"family": "Korpelainen", "given": "Eija", "initials": "E", "orcid": "0000-0002-4406-5602", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/7cd073ca51564b4eb9827a1ef59a6aff.json"}}], "type": "journal-article", "published": "2022-07-29", "journal": {"title": "F1000Res", "issn": "2046-1402", "volume": "11", "pages": "869", "issn-l": "2046-1402"}, "abstract": null, "doi": "10.12688/f1000research.122312.1", "pmid": null, "labels": [], "xrefs": [], "notes": [], "created": "2026-08-20T12:41:29.082Z", "modified": "2026-08-20T12:41:29.476Z"}, {"entity": "publication", "iuid": "9a81cb729e1c42df987c6cc4b52e6bba", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/9a81cb729e1c42df987c6cc4b52e6bba.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/9a81cb729e1c42df987c6cc4b52e6bba"}}, "title": "The Quest for Orthologs orthology benchmark service in 2022.", "authors": [{"family": "Nevers", "given": "Yannis", "initials": "Y", "orcid": "0000-0002-8604-2943", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/7e5e2aea9cc2433c880a3d650d4d0d5b.json"}}, {"family": "Jones", "given": "Tamsin E M", "initials": "TEM", "orcid": "0000-0002-0027-0858", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/966feebf7e9a43aea11edf9a4b531c90.json"}}, {"family": "Jyothi", "given": "Dushyanth", "initials": "D"}, {"family": "Yates", "given": "Bethan", "initials": "B", "orcid": "0000-0003-1658-1762", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/410431d70e2c41fea12f78f38aa58402.json"}}, {"family": "Ferret", "given": "Meritxell", "initials": "M"}, {"family": "Portell-Silva", "given": "Laura", "initials": "L"}, {"family": "Codo", "given": "Laia", "initials": "L", "orcid": "0000-0002-6797-8746", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/878c386adc4a4384bdea1e9f7a999832.json"}}, {"family": "Cosentino", "given": "Salvatore", "initials": "S"}, {"family": "Marcet-Houben", "given": "Marina", "initials": "M"}, {"family": "Vlasova", "given": "Anna", "initials": "A"}, {"family": "Poidevin", "given": "Laetitia", "initials": "L"}, {"family": "Kress", "given": "Arnaud", "initials": "A"}, {"family": "Hickman", "given": "Mark", "initials": "M"}, {"family": "Persson", "given": "Emma", "initials": "E"}, {"family": "Pili\u017eota", "given": "Ivana", "initials": "I"}, {"family": "Guijarro-Clarke", "given": "Cristina", "initials": "C"}, {"family": "OpenEBench team the Quest for Orthologs Consortium", "given": "", "initials": ""}, {"family": "Iwasaki", "given": "Wataru", "initials": "W", "orcid": "0000-0002-9169-9245", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/77399cc41820467ba6e32dd3ee6eaaec.json"}}, {"family": "Lecompte", "given": "Odile", "initials": "O"}, {"family": "Sonnhammer", "given": "Erik", "initials": "E", "orcid": "0000-0002-9015-5588", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/8c4fb5f5a50a4dbb91bbea3cc6861ffa.json"}}, {"family": "Roos", "given": "David S", "initials": "DS"}, {"family": "Gabald\u00f3n", "given": "Toni", "initials": "T"}, {"family": "Thybert", "given": "David", "initials": "D"}, {"family": "Thomas", "given": "Paul D", "initials": "PD", "orcid": "0000-0002-9074-3507", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/4af1f8a10ced487196829d162e22d314.json"}}, {"family": "Hu", "given": "Yanhui", "initials": "Y", "orcid": "0000-0003-1494-1402", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/d048ac84bf934c9d87774c6cab7430c6.json"}}, {"family": "Emms", "given": "David M", "initials": "DM"}, {"family": "Bruford", "given": "Elspeth", "initials": "E", "orcid": "0000-0002-8380-5247", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/3202468144774f85b3b80bd1cba9c84e.json"}}, {"family": "Capella-Gutierrez", "given": "Salvador", "initials": "S", "orcid": "0000-0002-0309-604X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/c76a6ff4986b42f58a0be702993eef42.json"}}, {"family": "Martin", "given": "Maria J", "initials": "MJ"}, {"family": "Dessimoz", "given": "Christophe", "initials": "C", "orcid": "0000-0002-2170-853X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/8d9dc970f3da45a4a46ecfdf4ab0893f.json"}}, {"family": "Altenhoff", "given": "Adrian", "initials": "A"}], "type": "meta-analysis", "published": "2022-07-05", "journal": {"title": "Nucleic Acids Res.", "issn": "1362-4962", "volume": "50", "issue": "W1", "pages": "W623-W632", "issn-l": "0305-1048"}, "abstract": "The Orthology Benchmark Service (https://orthology.benchmarkservice.org) is the gold standard for orthology inference evaluation, supported and maintained by the Quest for Orthologs consortium. It is an essential resource to compare existing and new methods of orthology inference (the bedrock for many comparative genomics and phylogenetic analysis) over a standard dataset and through common procedures. The Quest for Orthologs Consortium is dedicated to maintaining the resource up to date, through regular updates of the Reference Proteomes and increasingly accessible data through the OpenEBench platform. For this update, we have added a new benchmark based on curated orthology assertion from the Vertebrate Gene Nomenclature Committee, and provided an example meta-analysis of the public predictions present on the platform.", "doi": "10.1093/nar/gkac330", "pmid": "35552456", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC9252809"}, {"db": "pii", "key": "6584783"}], "notes": [], "created": "2026-08-20T09:49:48.053Z", "modified": "2026-08-20T09:49:48.299Z"}, {"entity": "publication", "iuid": "c2ed2a1f06b44dfcbb9852fd23014f05", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/c2ed2a1f06b44dfcbb9852fd23014f05.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/c2ed2a1f06b44dfcbb9852fd23014f05"}}, "title": "Author Correction: Leveraging European infrastructures to access 1 million human genomes by 2022.", "authors": [{"family": "Saunders", "given": "Gary", "initials": "G"}, {"family": "Baudis", "given": "Michael", "initials": "M"}, {"family": "Becker", "given": "Regina", "initials": "R", "orcid": "0000-0002-6711-8375", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/22936797d2c048d8aad8dff7f3c0513a.json"}}, {"family": "Beltran", "given": "Sergi", "initials": "S"}, {"family": "B\u00e9roud", "given": "Christophe", "initials": "C"}, {"family": "Birney", "given": "Ewan", "initials": "E"}, {"family": "Brooksbank", "given": "Cath", "initials": "C"}, {"family": "Brunak", "given": "S\u00f8ren", "initials": "S"}, {"family": "Van den Bulcke", "given": "Marc", "initials": "M"}, {"family": "Drysdale", "given": "Rachel", "initials": "R"}, {"family": "Capella-Gutierrez", "given": "Salvador", "initials": "S", "orcid": "0000-0002-0309-604X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/c76a6ff4986b42f58a0be702993eef42.json"}}, {"family": "Flicek", "given": "Paul", "initials": "P", "orcid": "0000-0002-3897-7955", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/82bb154b15a149a8b520e3943b3d5124.json"}}, {"family": "Florindi", "given": "Francesco", "initials": "F"}, {"family": "Goodhand", "given": "Peter", "initials": "P"}, {"family": "Gut", "given": "Ivo", "initials": "I"}, {"family": "Heringa", "given": "Jaap", "initials": "J"}, {"family": "Holub", "given": "Petr", "initials": "P", "orcid": "0000-0002-5358-616X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/f9ac554a034349f49a738a372ef849a2.json"}}, {"family": "Hooyberghs", "given": "Jef", "initials": "J"}, {"family": "Juty", "given": "Nick", "initials": "N"}, {"family": "Keane", "given": "Thomas M", "initials": "TM"}, {"family": "Korbel", "given": "Jan O", "initials": "JO"}, {"family": "Lappalainen", "given": "Ilkka", "initials": "I", "orcid": "0000-0001-5762-893X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/faa33524f1fb44e4b33f81cdce5dcfda.json"}}, {"family": "Leskosek", "given": "Brane", "initials": "B"}, {"family": "Matthijs", "given": "Gert", "initials": "G"}, {"family": "Mayrhofer", "given": "Michaela Th", "initials": "MT", "orcid": "0000-0001-6932-0473", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/3f21c093576c43679f69e4b3bcff86bf.json"}}, {"family": "Metspalu", "given": "Andres", "initials": "A"}, {"family": "Navarro", "given": "Arcadi", "initials": "A"}, {"family": "Newhouse", "given": "Steven", "initials": "S"}, {"family": "Nyr\u00f6nen", "given": "Tommi", "initials": "T"}, {"family": "Page", "given": "Angela", "initials": "A"}, {"family": "Persson", "given": "Bengt", "initials": "B"}, {"family": "Palotie", "given": "Aarno", "initials": "A"}, {"family": "Parkinson", "given": "Helen", "initials": "H"}, {"family": "Rambla", "given": "Jordi", "initials": "J"}, {"family": "Salgado", "given": "David", "initials": "D"}, {"family": "Steinfelder", "given": "Erik", "initials": "E"}, {"family": "Swertz", "given": "Morris A", "initials": "MA"}, {"family": "Valencia", "given": "Alfonso", "initials": "A"}, {"family": "Varma", "given": "Susheel", "initials": "S", "orcid": "0000-0003-1687-2754", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/e696015f301c4cff96a17cca3256dbd4.json"}}, {"family": "Blomberg", "given": "Niklas", "initials": "N"}, {"family": "Scollen", "given": "Serena", "initials": "S", "orcid": "0000-0002-9311-1337", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/754b8c996f6844f79fcf78be05efa72c.json"}}], "type": "published erratum", "published": "2019-11-00", "journal": {"title": "Nat. Rev. Genet.", "issn": "1471-0064", "volume": "20", "issue": "11", "pages": "702", "issn-l": "1471-0056"}, "abstract": "An amendment to this paper has been published and can be accessed via a link at the top of the paper.", "doi": "10.1038/s41576-019-0178-3", "pmid": "31520075", "labels": [], "xrefs": [{"db": "pii", "key": "10.1038/s41576-019-0178-3"}], "notes": [], "created": "2026-08-20T08:55:42.135Z", "modified": "2026-08-20T08:55:42.534Z"}, {"entity": "publication", "iuid": "740e1cc8cc814157a7284bda1a857b55", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/740e1cc8cc814157a7284bda1a857b55.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/740e1cc8cc814157a7284bda1a857b55"}}, "title": "An intrinsically disordered proteins community for ELIXIR.", "authors": [{"family": "Davey", "given": "Norman E", "initials": "NE"}, {"family": "Babu", "given": "M Madan", "initials": "MM"}, {"family": "Blackledge", "given": "Martin", "initials": "M"}, {"family": "Bridge", "given": "Alan", "initials": "A"}, {"family": "Capella-Gutierrez", "given": "Salvador", "initials": "S", "orcid": "0000-0002-0309-604X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/c76a6ff4986b42f58a0be702993eef42.json"}}, {"family": "Dosztanyi", "given": "Zsuzsanna", "initials": "Z"}, {"family": "Drysdale", "given": "Rachel", "initials": "R"}, {"family": "Edwards", "given": "Richard J", "initials": "RJ"}, {"family": "Elofsson", "given": "Arne", "initials": "A", "orcid": "0000-0002-7115-9751", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/248e70e81bd64f31a5f83e6e329bba95.json"}}, {"family": "Felli", "given": "Isabella C", "initials": "IC"}, {"family": "Gibson", "given": "Toby J", "initials": "TJ"}, {"family": "Gutmanas", "given": "Aleksandras", "initials": "A", "orcid": "0000-0001-6311-0176", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/47708ac9f7ee4c569349120dd2db2cc1.json"}}, {"family": "Hancock", "given": "John M", "initials": "JM", "orcid": "0000-0003-2991-2217", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/fc4a5d59b2d44f1bb0c166fa7fe3ec36.json"}}, {"family": "Harrow", "given": "Jen", "initials": "J"}, {"family": "Higgins", "given": "Desmond", "initials": "D"}, {"family": "Jeffries", "given": "Cy M", "initials": "CM"}, {"family": "Le Mercier", "given": "Philippe", "initials": "P", "orcid": "0000-0001-8528-090X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/5aff6c12999c426ea8867f6e345adac6.json"}}, {"family": "M\u00e9sz\u00e1ros", "given": "Balint", "initials": "B"}, {"family": "Necci", "given": "Marco", "initials": "M"}, {"family": "Notredame", "given": "Cedric", "initials": "C"}, {"family": "Orchard", "given": "Sandra", "initials": "S", "orcid": "0000-0002-8878-3972", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/869478a873ea4465ab43ecef5aee865c.json"}}, {"family": "Ouzounis", "given": "Christos A", "initials": "CA"}, {"family": "Pancsa", "given": "Rita", "initials": "R"}, {"family": "Papaleo", "given": "Elena", "initials": "E"}, {"family": "Pierattelli", "given": "Roberta", "initials": "R", "orcid": "0000-0001-7755-0885", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/76fb4aa8c0824df09a4d8af9bfd2990f.json"}}, {"family": "Piovesan", "given": "Damiano", "initials": "D"}, {"family": "Promponas", "given": "Vasilis J", "initials": "VJ", "orcid": "0000-0003-3352-4831", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/814e650453b44d0c99b86091ee27669a.json"}}, {"family": "Ruch", "given": "Patrick", "initials": "P"}, {"family": "Rustici", "given": "Gabriella", "initials": "G"}, {"family": "Romero", "given": "Pedro", "initials": "P", "orcid": "0000-0002-6995-5193", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/5b6be817efdc4e1fb23cc30dd2a1f6ba.json"}}, {"family": "Sarntivijai", "given": "Sirarat", "initials": "S"}, {"family": "Saunders", "given": "Gary", "initials": "G"}, {"family": "Schuler", "given": "Benjamin", "initials": "B"}, {"family": "Sharan", "given": "Malvika", "initials": "M"}, {"family": "Shields", "given": "Denis C", "initials": "DC"}, {"family": "Sussman", "given": "Joel L", "initials": "JL"}, {"family": "Tedds", "given": "Jonathan A", "initials": "JA"}, {"family": "Tompa", "given": "Peter", "initials": "P"}, {"family": "Turewicz", "given": "Michael", "initials": "M", "orcid": "0000-0003-0737-1114", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/d6f5ef7ecd8f429f8a1a19026ae254b0.json"}}, {"family": "Vondrasek", "given": "Jiri", "initials": "J"}, {"family": "Vranken", "given": "Wim F", "initials": "WF"}, {"family": "Wallace", "given": "Bonnie Ann", "initials": "BA"}, {"family": "Wichapong", "given": "Kanin", "initials": "K"}, {"family": "Tosatto", "given": "Silvio C E", "initials": "SCE"}], "type": "journal article", "published": "2019-10-15", "journal": {"title": "F1000Res", "issn": "2046-1402", "volume": "8", "issn-l": "2046-1402"}, "abstract": "Intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs) are now recognised as major determinants in cellular regulation. This white paper presents a roadmap for future e-infrastructure developments in the field of IDP research within the ELIXIR framework. The goal of these developments is to drive the creation of high-quality tools and resources to support the identification, analysis and functional characterisation of IDPs. The roadmap is the result of a workshop titled \"An intrinsically disordered protein user community proposal for ELIXIR\" held at the University of Padua. The workshop, and further consultation with the members of the wider IDP community, identified the key priority areas for the roadmap including the development of standards for data annotation, storage and dissemination; integration of IDP data into the ELIXIR Core Data Resources; and the creation of benchmarking criteria for IDP-related software. Here, we discuss these areas of priority, how they can be implemented in cooperation with the ELIXIR platforms, and their connections to existing ELIXIR Communities and international consortia. The article provides a preliminary blueprint for an IDP Community in ELIXIR and is an appeal to identify and involve new stakeholders.", "doi": "10.12688/f1000research.20136.1", "pmid": "31824649", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC6880265"}, {"db": "pii", "key": "ELIXIR-1753"}], "notes": [], "created": "2026-08-20T12:41:35.065Z", "modified": "2026-08-20T12:41:35.308Z"}]}